caryophyllene-oxide and beta-eudesmol

The chemical composition of essential oil obtained from the aerial parts of Ajuga comata Stapf. was analyzed by GC and GC/MS. Thirty-seven components were identified in the oil. (E)-β-caryophyllene (30.9%), caryophyllene oxide (24.9%), (E)-β-farnesene (12.6%), β-eudesmol (3.2%), δ-cadinene (3.1%) and germacrene D (3.0%) were the main compounds in the EOs. The chemical composition of A. comata Stapf. from the Southern Zagros of Iran is reported for the first time.

Topics: Ajuga; Gas Chromatography-Mass Spectrometry; Iran; Oils, Volatile; Polycyclic Sesquiterpenes; Sesquiterpenes; Sesquiterpenes, Eudesmane; Sesquiterpenes, Germacrane

Kaliphora madagascariensis is an evergreen shrub or small tree endemic to Madagascar where it is traditionally used for the treatment of persistent cephalalgia by a strong inhalation of its odour. In this work, we analysed for the first time the essential oil obtained from leaves by Gas Chromatography-Mass Spectrometry. The chemical composition was dominated by oxygenated sesquiterpenes (68.1%), with caryophyllene oxide (14.7%) and β-eudesmol (10.7%) as the most abundant constituents. These compounds are endowed with documented healthy effects such as analgesic, anti-inflammatory, neuritogenic, antiepileptic and hypotensive, and its abundance might explain the traditional use of the plant in Madagascar.

Topics: Gas Chromatography-Mass Spectrometry; Madagascar; Magnoliopsida; Oils, Volatile; Plant Leaves; Plant Oils; Polycyclic Sesquiterpenes; Sesquiterpenes; Sesquiterpenes, Eudesmane

The essential oil obtained by hydrodistillation from leaves of Anaxagorea brevipes was analysed by gas chromatography fitted with a flame ionisation detector (GC-FID) and coupled to mass spectrometry (GC-MS). Thirty one components were identified, representing around 75.7% of total oil. The major components were β-eudesmol (13.16%), α-eudesmol (13.05%), γ-eudesmol (7.54%), guaiol (5.12%), caryophyllene oxide (4.18%) and β-bisabolene (4.10%). The essential oil showed antimicrobial activity against Gram-positive bacteria and yeast with the MIC values between 25.0 and 100 μg/mL. The highest antiproliferative activity was observed for the oil against MCF-7 (breast, TGI = 12.8 μg/mL), NCI-H460 (lung, TGI = 13.0 μg/mL) and PC-3 (prostate, TGI = 9.6 μg/mL) cell lines, while against no cancer cell line HaCat (keratinocyte) the TGI was 38.8 μg/mL. The oil exhibited a small antioxidant activity assessed through ORAC-FL assay (517 μmol TE/g). This is the first report regarding the chemical composition and bioactivity of A. brevipes essential oil.

Topics: Annonaceae; Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Cell Line, Tumor; Flame Ionization; Free Radical Scavengers; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Monocyclic Sesquiterpenes; Oils, Volatile; Plant Leaves; Polycyclic Sesquiterpenes; Sesquiterpenes; Sesquiterpenes, Eudesmane; Sesquiterpenes, Guaiane; Yeasts

The chemical composition of volatile oil obtained from aerial parts of Pavonia odorata were investigated using gas chromatography-mass spectrometry (GC-MS). Its aroma-active compounds were identified using gas chromatography-olfactometry (GC-O) and aroma extraction dilution analysis (AEDA). In order to determine the relative contribution of each compound to the aroma of P. odorata, relative flavour activity (RFA) was calculated. The hydrodistillation of P. odorata afforded yellowish oil and the yield was 0.009% (w/w) with a spicy, sweet, and green odour. Eighty-five compounds were identified in the oil by GC-MS; the major constituents of the volatile oil were ageratochromene (11.95%), palmitic acid (9.95%), hexahydrofarnesyl acetone (5.96%), β-eudesmol (4.53%) and β-caryophyllene oxide (3.08%). The most characteristic aroma compounds in the volatile oil were identified for β-caryophyllene oxide (FD-factor = 128, spicy), (E)-pinocarveol (FD-factor = 64, sweet), 3-butylpyridine (FD-factor = 64, spicy), and 2-nonanone (FD-factor = 32, green) by GC-MS, GC-O and AEDA. It seems that these compounds are responsible for the spicy, sweet and green odour of the aerial parts of P. odorata. The antioxidant activity of the volatile oil was also investigated by the oxygen radical absorbance capacity (ORAC) assay using fluorescein (FL) as the fluorescent probe. The ORAC value of the oil was 594.2 ± 25.9 μM TE/g. The results indicated that the volatile oil from the aerial parts of P. odorata could be considered as a natural antioxidant effect agent.

Topics: Antioxidants; Benzopyrans; Bicyclic Monoterpenes; Distillation; Gas Chromatography-Mass Spectrometry; Indicator Dilution Techniques; Ketones; Malvaceae; Medicine, Ayurvedic; Monoterpenes; Odorants; Oils, Volatile; Olfactometry; Palmitic Acid; Plant Components, Aerial; Polycyclic Sesquiterpenes; Sesquiterpenes; Sesquiterpenes, Eudesmane; Terpenes

Composition of the essential oil obtained from dried flowering aerial parts of Teucrium scordium L. (Labiatae) was analyzed by GC and GC/MS. Fifty-six components were identified in the essential oil of T. scordium. The major constituents of the oil were beta-caryophyllene (22.8%), (E)-beta-farnesene (10.4%), caryophyllene oxide (8.6%), 1,8-cineole (6.1%) and beta-eudesmol (5.1%).

Topics: Chromatography, Gas; Cyclohexanols; Eucalyptol; Flowers; Gas Chromatography-Mass Spectrometry; Monoterpenes; Oils, Volatile; Plant Oils; Polycyclic Sesquiterpenes; Sesquiterpenes; Sesquiterpenes, Eudesmane; Teucrium