caryophyllene and isolongifolol

The chemical composition of the essential oil obtained from the aerial parts of Betonica grandiflora Willd., growing wild in Iran, was analysed by gas chromatography-mass spectrometry for the first time. Overall, 40 volatile components were identified on the basis of their mass spectra characteristics and retention indices in which ledol (21.8%), myrtenyl acetate (21.7%), eudesm-7(11)-en-4-ol (6.5%), trans-caryophyllene (5.5%), α-bisabolol (4.9%) and isolongifolol (4.5%) were the major constituents. Oxygenated sesquiterpenes, monoterpene hydrocarbons and sesquiterpene hydrocarbons were the main groups of compounds with 45.6%, 23.1% and 18.4%, respectively. The oil was moderately active against Bacillus subtilis and Staphylococcus aureus and inactive against Enterococcus faecalis and Klebsiella pneumoniae.

Topics: Anti-Bacterial Agents; Bacillus subtilis; Enterococcus faecalis; Gas Chromatography-Mass Spectrometry; Iran; Klebsiella pneumoniae; Microbial Sensitivity Tests; Monocyclic Sesquiterpenes; Monoterpenes; Oils, Volatile; Plant Components, Aerial; Polycyclic Sesquiterpenes; Sesquiterpenes; Stachys; Staphylococcus aureus