carvedilol and simvastatin

carvedilol has been researched along with simvastatin in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (50.00)29.6817
2010's5 (41.67)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Casciano, CN; Clement, RP; Johnson, WW; Wang, EJ1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Ahn, Y; Cho, JG; Hong, SN; Hong, YJ; Hwang, SH; Jeong, MH; Kang, JC; Kim, JH; Kim, KH; Lee, SR; Park, HW; Park, JC; Yun, NS1
Rifkin, SI1
Ingber, A; Moshe, S; Neumark, M; Slodownik, D1
Baiges, A; Bosch, J; Hernández-Gea, V1
Grohganz, H; Jensen, KT; Kasten, G; Meng-Lund, H; Pantsar, T; Poso, A; Rades, T; Rantanen, J1
Arora, V; Choudhary, A; Jindal, A; Kumar, G; Sarin, SK; Vijayaraghavan, R1

Reviews

2 review(s) available for carvedilol and simvastatin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Pharmacologic prevention of variceal bleeding and rebleeding.
    Hepatology international, 2018, Volume: 12, Issue:Suppl 1

    Topics: Adrenergic beta-Antagonists; Atorvastatin; Carbazoles; Carvedilol; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Hemodynamics; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Portal; Incidence; Liver; Liver Cirrhosis; Nitric Oxide Synthase Type III; Portal Pressure; Propanolamines; Propranolol; Simvastatin; Splanchnic Circulation

2018

Trials

1 trial(s) available for carvedilol and simvastatin

ArticleYear
Hemodynamic Effects of Adding Simvastatin to Carvedilol for Primary Prophylaxis of Variceal Bleeding: A Randomized Controlled Trial.
    The American journal of gastroenterology, 2020, Volume: 115, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Carvedilol; Drug Therapy, Combination; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Hemodynamics; Hepatic Veins; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver Cirrhosis; Male; Middle Aged; Portal Pressure; Primary Prevention; Simvastatin; Treatment Outcome; Venous Pressure

2020

Other Studies

9 other study(ies) available for carvedilol and simvastatin

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Active transport of fluorescent P-glycoprotein substrates: evaluation as markers and interaction with inhibitors.
    Biochemical and biophysical research communications, 2001, Nov-30, Volume: 289, Issue:2

    Topics: 3T3 Cells; Adrenergic Uptake Inhibitors; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Biological Transport, Active; Cell Line; Cell Separation; Cell Survival; Flow Cytometry; Fluorescent Dyes; Humans; Inhibitory Concentration 50; Mice; Protein Binding; Reserpine; Spectrometry, Fluorescence; Substrate Specificity; Time Factors

2001
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Effect of combination therapy with simvastatin and carvedilol in patients with left ventricular dysfunction complicated with acute myocardial infarction who underwent percutaneous coronary intervention.
    Circulation journal : official journal of the Japanese Circulation Society, 2006, Volume: 70, Issue:10

    Topics: Aged; Angioplasty, Balloon, Coronary; Carbazoles; Carvedilol; Death; Disease-Free Survival; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Myocardial Infarction; Propanolamines; Retrospective Studies; Simvastatin; Stroke Volume; Treatment Outcome; Ventricular Dysfunction, Left

2006
Multiple drug interactions in a renal transplant patient leading to simvastatin-induced rhabdomyolysis: a case report.
    Medscape journal of medicine, 2008, Volume: 10, Issue:11

    Topics: Acetanilides; Adrenergic alpha-Antagonists; Calcium Channel Blockers; Carbazoles; Carvedilol; Diltiazem; Drug Interactions; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney Transplantation; Male; Middle Aged; Piperazines; Propanolamines; Ranolazine; Rhabdomyolysis; Simvastatin

2008
Occupational airborne contact dermatitis to simvastatin, carvedilol, and zolpidem.
    Contact dermatitis, 2009, Volume: 61, Issue:1

    Topics: Adult; Air Pollutants, Occupational; Carbazoles; Cardiovascular Agents; Carvedilol; Dermatitis, Occupational; Humans; Hypnotics and Sedatives; Male; Propanolamines; Pyridines; Simvastatin; Zolpidem

2009
The use of molecular descriptors in the development of co-amorphous formulations.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2018, Jul-01, Volume: 119

    Topics: Amino Acids; Carbamazepine; Carbazoles; Carvedilol; Chemistry, Pharmaceutical; Discriminant Analysis; Drug Combinations; Drug Stability; Furosemide; Indomethacin; Least-Squares Analysis; Mebendazole; Models, Molecular; Pharmaceutical Preparations; Powder Diffraction; Propanolamines; Simvastatin; X-Ray Diffraction

2018