carvedilol has been researched along with propranolol in 156 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (3.21) | 18.7374 |
| 1990's | 27 (17.31) | 18.2507 |
| 2000's | 51 (32.69) | 29.6817 |
| 2010's | 56 (35.90) | 24.3611 |
| 2020's | 17 (10.90) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Baker, JG | 1 |
| Carrupt, PA; Guillarme, D; Henchoz, Y; Rudaz, S; Veuthey, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
| Faller, B; Trunzer, M; Zimmerlin, A | 1 |
| Bard, B; Carrupt, PA; Martel, S | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Bednarski, M; Filipek, B; Groszek, G; Nowak-Król, A; Otto, M; Swierczyński, D; Walczak, M; Wdowik, T | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Cegła, M; Filipek, B; Marona, H; Pytka, K; Rapacz, A; Siwek, A; Szkaradek, N | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Filipek, B; Gryboś, A; Kubacka, M; Marona, H; Mogilski, S; Pańczyk, K; Siwek, A; Szkaradek, N; Waszkielewicz, AM; Żmudzki, P | 1 |
| Cantillon, DM; Derudas, M; Huckvale, R; Kenyon, EJ; Kirkwood, NK; Kros, CJ; O'Reilly, M; Richardson, GP; Waddell, SJ; Ward, SE | 1 |
| Chang, Q; Chen, Z; Hu, G; Hu, L; Li, Q; Long, J | 1 |
| Wendt, T | 1 |
| Bril, A; DiMartino, MJ; Feuerstein, GZ; Linee, P; Poyser, RH; Ruffolo, RR; Slivjak, M; Smith, EF | 1 |
| Gagnon, R; Slivjak, MJ; Smith, EF | 1 |
| Nahrendorf, W; Rading, A; Schlote, A; Steinig, G; van der Does, R | 1 |
| Bril, A; Feuerstein, GZ; Hamburger, SA; Ruffolo, RR; Smith, EF | 1 |
| James, IM; McLaughlin, K; Munro, C; Yogendran, L | 1 |
| Bristow, MR; Handwerger, D; Klein, J; Larrabee, P; Minobe, W; Müller-Beckmann, B; Port, JD; Roden, R; Skerl, L | 1 |
| Frey, G; Kaltenbach, M; Kober, G; Schmidt, T; Schräder, R; Sievert, H; van der Does, R | 2 |
| Imai, S; Ishibashi, T; Kawada, T; Nakazawa, M; Satoh, S | 1 |
| Betterridge, DJ; Gasser, JA | 1 |
| Hirohashi, M; Iwasaki, S; Maekawa, K; Nomura, M; Taguchi, K; Takasuna, K; Tamura, K; Yamada, S; Yamaguchi, K; Yoshida, M | 1 |
| Kober, G; Landgraf, H; Schräder, R; van der Does, R; Wendt, T | 1 |
| Cronin, CJ; Graham, BR; Prichard, BN; Tomlinson, B | 1 |
| Hoffmeister, HM; Ickrath, O; Karsch, KR; Mauser, M; Voelker, W | 1 |
| Bompart, F; Graham, BR; Liu, JB; Prichard, BN; Tomlinson, B | 1 |
| Eggertsen, R | 1 |
| Nagano, T; O'Harrow, S; Sponer, G; Zimmer, HG | 1 |
| Belz, GG; Breithaupt-Grögler, K; De Mey, C; Palm, D; Schloos, J | 1 |
| Belz, GG; Breithaupt, K; de Mey, C; Neugebauer, G; Palm, D; Schloos, J | 1 |
| Bril, A; Feuerstein, GZ; Ruffolo, RR | 1 |
| Berge, RK; Brunvand, H; Grong, K; Kvitting, PM; Rynning, SE | 1 |
| Barone, FC; Campbell, WG; Feuerstein, GZ; Laragh, JH; Nelson, AH; Ohlstein, EH; Sealey, JE; Willette, RN | 1 |
| Bijou, R; Demopoulos, L; Gentilucci, M; Jones, M; Katz, SD; LeJemtel, TH; Mancini, D; Testa, M; Yeh, M | 1 |
| Fyhrquist, F; Metsärinne, K; Saijonmaa, O | 1 |
| Hashimoto, H; Matsuda, K; Nakamura, A; Sekiguchi, F; Shibutani, T; Shimamura, K; Sunano, S; Tanaka, M; Yamamoto, K | 1 |
| De Mey, C | 1 |
| Gabriels, M; Vamecq, J; Van den Branden, C; Vanden Houte, K; Verbeelen, D | 1 |
| Arch, JR; Cheng, HY; Feuerstein, G; Hieble, JP; Liu, GL; Ma, XL; Ruffolo, RR; Yue, TL | 1 |
| Lercher, P; Liebmann, P; Lindner, W; Maier, R; Sakotnik, A; Stoschitzky, K; Zweiker, R | 1 |
| Bañares, R; Bosch, J; Casado, M; de Diego, A; García-Pagán, JC; Moitinho, E; Piqueras, B | 1 |
| Carson, PE | 1 |
| Forrest, E; Hayes, P; Stanley, A | 1 |
| Ikeda, U; Kurosaki, K; Maeda, Y; Shimada, K | 1 |
| Blendis, L; Wong, F | 1 |
| Bristow, MR; Ferguson, D; Lindenfeld, J; Lowes, BD; Noori, A; Wolfel, E | 1 |
| Bernocchi, P; Boraso, A; Cargnoni, A; Ceconi, C; Curello, S; Ferrari, R; Parrinello, G | 1 |
| Boldi, E; Dei Cas, L; Metra, M; Nodari, S | 1 |
| Ijiri, H; Ishihara, T; Kohno, I; Komori, S; Matsumura, K; Osada, M; Sawanobori, T; Takusagawa, M; Tamura, K; Umetani, K | 1 |
| Aoyama, M; Fukutomi, T; Horio, T; Ito, S; Itoh, M; Nakata, K; Suzuki, S; Suzumura, H; Takeda, Y; Yamada, Y | 1 |
| D'Agostino, B; Falciani, M; Filippelli, A; Mazzeo, F; Nobili, B; Rinaldi, B; Rossi, F; Rossi, S | 1 |
| Doze, P; Elsinga, PH; Maas, B; Vaalburg, W; Van Waarde, A; Wegman, T | 1 |
| Gorbunova, TIu; Mal'tseva, IA; Strel'tsova, NN; Vasil'ev, AP; Zykova, EL | 1 |
| Dubova, TV; Gorbunova, TIu; Strel'tsova, NN; Vasil'ev, AP | 1 |
| Maehara, K; Maruyama, Y; Sakabe, A; Yaoita, H | 1 |
| Biswas, PK; Das, D; De, BK; Maity, AK; Majumdar, D; Mandal, SK; Sen, S | 1 |
| Sarukhanian, OV; Sisakian, AS; Torgomian, TG | 1 |
| Lee, YC | 1 |
| Bruns, LA; Canter, CE | 1 |
| Abraldes, JG; Albillos, A; Bañares, R; Bosch, J; De Diego, A; García-Pagán, JC; Lampreave, JL; Matilla, A; Moitinho, E; Piera, C | 1 |
| Danihelová, E; Jancinová, V; Májeková, M; Nosál, R; Petríková, M | 1 |
| Gorbunova, TIu; Strel'tsova, NN; Vasil'ev, AP | 2 |
| Matsumori, A; Nishio, R; Sasayama, S; Shioi, T | 1 |
| Castro, VJ | 1 |
| Kihara, Y; Kishimoto, C; Onozawa, Y; Shioji, K; Takenaka, H; Yuan, Z | 1 |
| Hemstreet, BA | 1 |
| Asada, A; Maeda, K; Nakamura, M; Watanabe, T; Yasunari, K; Yoshikawa, J | 1 |
| Kishimoto, C; Nimata, M; Shioji, K; Yuan, Z | 1 |
| Asakura, M; Asano, Y; Asanuma, H; Hori, M; Kim, J; Kitakaze, M; Kitamura, S; Liao, Y; Minamino, T; Mori, H; Node, K; Ogai, A; Ogita, H; Sanada, S; Shinozaki, Y; Shintani, Y; Takashima, S; Tomoike, H | 1 |
| Hou, MC; Huang, YT; Lee, FY; Lee, SD; Lin, HC; Yang, YY | 1 |
| Gonçalves, L; Monteiro, P; Moreno, AJ; Oliveira, PJ; Palmeira, CM; Providência, LA; Rolo, AP; Sardão, VA | 1 |
| Fabryova, V; Jancinova, V; Majekova, M; Nosal, R; Petrikova, M | 1 |
| Kähönen, M; Kööbi, T; Nieminen, T; Ylitalo, P; Ylitalo, R | 1 |
| Christ, T; Kaumann, A; Molenaar, P; Ravens, U | 1 |
| Abe, H; Anson, BD; Delisle, BP; January, CT; Kawakami, K; Kikuchi, K; Nagatomo, T; Nakashima, Y; Takemasa, H | 1 |
| Fonarow, GC | 1 |
| Auge, D; Bachmakov, I; Endress, B; Fromm, MF; Werner, U | 1 |
| Goyagi, T; Kimura, T; Masaki, Y; Nishikawa, T; Tobe, Y | 1 |
| Fujii, N; Igarashi, N; Igawa, A; Inoue, H; Matsuki, A; Nakadate, T; Nozawa, T; Suzuki, T | 1 |
| Cai, Y; Jia, J; Li, S; Liu, G; Liu, Y; Pan, C; Ren, J; Yu, C | 1 |
| Bhatt, P; Goyal, R; Makwana, D; Santani, D | 1 |
| Ajmo, CT; Collier, LA; Cuevas, J; Green, SM; Hall, AA; Leonardo, CC; Pennypacker, KR; Willing, AE; Womble, TA | 1 |
| Bankston, JR; Kass, RS | 1 |
| Bachmakov, I; Endress, B; Fromm, MF; Glaeser, H; König, J; Mörl, F | 1 |
| Hayes, PC; Tripathi, D | 1 |
| Castro, RB; Gallo, L; Maciel, BC; Marques, F; Nobre, F; Pintya, AO; Simões, MV | 1 |
| Cai, H; Chen, WQ; Ji, XP; Zhang, C; Zhang, Y | 1 |
| Lopes, CM; O-Uchi, J | 1 |
| Tzingounis, AV; von Zastrow, M; Yudowski, GA | 1 |
| Pisklak, DM; Wawer, I; Zielińska-Pisklak, MA | 1 |
| Ferlitsch, A; Homoncik, M; Payer, BA; Peck-Radosavljevic, M; Pinter, M; Reiberger, T | 1 |
| Bendtsen, F; Feldager Hansen, E; Grønbæk, H; Hobolth, L; Møller, S; Roelsgaard, K | 1 |
| Onay-Besikci, A; Ozcelikay, AT; Suzmecelik, E | 1 |
| Fujita, M; Hirano, E; Kimura, T; Kishimoto, C; Shimada, K | 1 |
| Bonefeld, K; Hobolth, L; Juul, A; Møller, S | 1 |
| Ferlitsch, A; Heinisch, BB; Kramer, L; Payer, BA; Peck-Radosavljevic, M; Pinter, M; Reiberger, T; Schwabl, P; Trauner, M; Ulbrich, G | 1 |
| Bendtsen, F; Hansen, EF; Hobolth, L; Møller, S | 1 |
| D'Amico, G; D'Amico, M; Perricone, G; Sinagra, E; Tinè, F | 1 |
| Augustin, S; Esteban, R; Ezkurdia, N; Genescà, J; Martell, M; Raurell, I; Rodríguez, S | 1 |
| Cao, JM; Chan, GC; Chan, S; Chen, MP; Cheung, YF | 1 |
| Szeląg, A; Szumny, D | 1 |
| Annaert, P; Augustijns, P; Stappaerts, J; Tack, J; Wuyts, B | 1 |
| Coelho, M; Correia, G; Medeiros, R; Moz, M; Ribeiro, L; Teixeira, A | 1 |
| Huang, B; Li, HH; Li, YX; Liu, X; Ma, L; Tao, YZ | 1 |
| Bond, RA; Bouvier, M; Forkuo, GS; Joshi, R; Knoll, BJ; Leff, P; Parra, S; Thanawala, VJ; Valdez, DJ | 1 |
| Farajzadeh, MA; Fazeli-Bakhtiyari, R; Jouyban, A; Somi, MH; Sorouraddin, MH | 1 |
| Al Dakhoul, S; Alabed, S; Bdaiwi, Y; Frobel-Mercier, AK; Sabouni, A | 1 |
| Fang, X; Li, N; Li, Z; Sun, Y; Wu, J; Yuan, J; Zhang, M; Zhang, Y; Zhao, R; Zhou, W | 1 |
| Belgaumkar, A; Chen, X; Huang, Y; Ke, W; Li, J; Li, T; Sun, P; Xian, W; Zheng, Q | 1 |
| Baik, SK; Jang, JY; Jeong, SW; Kim, DJ; Kim, MY; Kim, SG; Kim, TY; Kim, YS; Lee, B; Seo, YS; Sohn, JH; Suk, KT; Um, SH | 1 |
| Ballesteros-Esteban, T; Cárdenas, S; Lucena, R; Reyes-Gallardo, EM; Valcárcel, M | 1 |
| Gupta, V; Rawat, R; Saraya, A | 1 |
| Gerbes, AL; Steib, CJ | 1 |
| Lo, GH | 1 |
| Kim, SG; Sohn, JH | 1 |
| Fallowfield, JA; Hayes, PC; Jayaswal, ANA; Lachlan, NJ; Lilburn, DML; Macnaught, G; McDonald, N; Patel, D; Semple, SI | 1 |
| Hasan, W; Khan, F; Mudd, JO; Thornburg, KL; Toyooka, A; Tyrrell, C | 1 |
| Baumann-Durchschein, F; Bucsics, T; Datz, C; Dolak, W; Ferlitsch, A; Fickert, P; Finkenstedt, A; Graziadei, I; Hametner, S; Karnel, F; Krones, E; Maieron, A; Mandorfer, M; Peck-Radosavljevic, M; Püspök, A; Rainer, F; Reiberger, T; Schoder, M; Schöfl, R; Schwabl, P; Stadlbauer, V; Stauber, R; Tilg, H; Trauner, M; Zoller, H | 1 |
| Madias, JE | 1 |
| Tornvall, P; Y-Hassan, S | 1 |
| Abd ElRahim, AY; Elsharkawy, A; Fathalah, W; Fouad, R; Khairy, M; Khatamish, H; Khorshid, O; Moussa, M; Seyam, M | 1 |
| Baiges, A; Bosch, J; Hernández-Gea, V | 1 |
| Benten, D; Karkmann, K; Kluwe, J; Piecha, F; Rünzi, AC; Schulz, L; von Wulffen, M; Wege, H | 1 |
| Hayes, P; Robertson, M | 1 |
| Casali, KR; Dartora, DR; Dias, LD; Eibel, B; Irigoyen, MC; Kalil, RAK; Kristochek, M; Lehnen, AM; Markoski, MM; Peres, TR | 1 |
| Addison, D; Alam, M; Jneid, H; Kayani, W; Lakkis, N; Misra, A; Pham, D; Resar, J | 1 |
| Bendtsen, F; Gluud, LL; Hobolth, L; Jeyaraj, R; Morgan, MY; Zacharias, AP | 1 |
| Abdel-Kawy, HS | 1 |
| Abraldes, JG; Albillos, A; Alvarado, E; Aracil, C; Augustin, S; Bañares, R; Bosch, J; Calleja, JL; Garcia-Pagan, JC; Genescà, J; Morillas, RM; Peñas, B; Poca, M; Torres, F; Villanueva, C | 1 |
| Du, XJ; Hu, HY; Kiriazis, H; Lu, Q; Nguyen, MN; Puthalakath, H; Sadoshima, J; Su, Y; Wang, LN; Zhao, WB; Ziemann, M | 1 |
| Bunchorntavakul, C; Reddy, KR | 1 |
| Andrews, LM; Koch, BCP; van der Nagel, BCH; van Domburg, B | 1 |
| Dickerson, E; Duckett, MM; Dusenbery, K; Khammanivong, A; Lawrence, J; Nguyen, L; Phung, SK | 1 |
| Driessen, RJB; Logger, JGM; Olydam, JI | 1 |
| Al Dakhoul, S; Alabed, S; Bdaiwi, Y; Sabouni, A | 1 |
| Aggelis, N; Baltayiannis, G; Christaki, M; Christodoulou, D; Despotis, G; Fillipas-Ntekouan, S; Fotopoulos, A; Kalambokis, GN; Koustousi, C; Lakkas, L; Michalis, LK; Milionis, H; Pappas, K; Sergianiti, F; Tsiakas, I; Tsiouris, S; Xourgia, X | 1 |
| Jacobsen, SJ; Kalantar-Zadeh, K; Kovesdy, CP; Lee, MS; Neyer, JR; Shaw, SF; Shi, J; Sim, JJ; Zhou, H | 1 |
| Assadi, M; Dehdar, F; Esmaeeli, A; Keshavarz, Z; Seyedabadi, M | 1 |
| Cançado, GGL; Cardoso, JB; Couto, CA; de Abreu, ES; Faria, LC; Ferrari, TCA; Lima, AMC; Nardelli, MJ; Osório, FMF | 1 |
| Balcar, L; Bauer, D; Hartl, L; Hofer, B; Jachs, M; Mandorfer, M; Paternostro, R; Pfisterer, N; Pinter, M; Reiberger, T; Scheiner, B; Schwarz, M; Simbrunner, B; Stättermayer, AF; Trauner, M | 1 |
| Ahmad, EA; El-Naggar, ME; Ibrahim, IAAE; Mahmoud, MF; Mohamed, RMSM; Omran, BHF; Sakr, AT | 1 |
| Cheng, D; Fan, X; Liu, X; Ma, L; Wang, F; Wu, J; Yan, E | 1 |
| La Mura, V; Reiberger, T; Turco, L; Vitale, G | 1 |
| Bai, B; Chen, YP; Dai, EH; Gao, C; Gao, YF; Guo, XR; Hu, GQ; Hu, QG; Huan, H; Huang, MX; Huang, SD; Jin, SQ; Li, JH; Li, W; Liu, ZJ; Lu, MZ; Ma, QP; Meng, ZJ; Qi, XL; Song, YL; Tang, QY; Wang, JT; Wang, Y; Xu, Z; Yang, JH; Zeng, QL; Zhang, QH; Zheng, S; Zhu, Y; Zu, HM | 1 |
| Parikh, ND; Tapper, EB | 1 |
| Aneeza Ilyas, -; Khalid Mahmud Khan, -; Maria, -; Muhammad Adnan Iqbal, -; Muhammad Farooq Hanif, -; Nooman Gilani, -; Raja Omer Fiaz, - | 1 |
19 review(s) available for carvedilol and propranolol
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Inverse PK/PD: estimation and differentiation of bioavailability from effect kinetics--observations with beta-adrenoceptor antagonists.
Topics: Adrenergic beta-Antagonists; Adult; Binding, Competitive; Biological Availability; Carbazoles; Carvedilol; Clinical Trials as Topic; Dose-Response Relationship, Drug; Heart Rate; Humans; Male; Models, Biological; Propanolamines; Propranolol; Randomized Controlled Trials as Topic; Tachycardia | 1997 |
Beta-blocker therapy in heart failure: pathophysiology and clinical results.
Topics: Adrenergic beta-Antagonists; Aged; Bisoprolol; Carbazoles; Carvedilol; Clinical Trials as Topic; Exercise; Heart Failure; Heart Rate; Hemodynamics; Humans; Imidazoles; Male; Metoprolol; Middle Aged; Propanolamines; Propranolol; Quality of Life; Stroke Volume; Time Factors; Vasodilator Agents; Xamoterol | 1999 |
Should beta-blockers be used for the treatment of pediatric patients with chronic heart failure?
Topics: Adolescent; Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Child; Child, Preschool; Chronic Disease; Clinical Trials as Topic; Heart Failure; Humans; Infant; Infant, Newborn; Metoprolol; Propanolamines; Propranolol; Treatment Outcome | 2002 |
Evaluation of carvedilol for the treatment of portal hypertension.
Topics: Adrenergic Antagonists; Carbazoles; Carvedilol; Esophageal and Gastric Varices; Fibrosis; Humans; Hypertension, Portal; Meta-Analysis as Topic; Propanolamines; Propranolol | 2004 |
Beta-blockers for the post-myocardial infarction patient: current clinical evidence and practical considerations.
Topics: Adrenergic beta-Antagonists; Algorithms; Atenolol; Carbazoles; Carvedilol; Humans; Myocardial Infarction; Practice Guidelines as Topic; Propanolamines; Propranolol; Randomized Controlled Trials as Topic; Secondary Prevention; Timolol | 2006 |
The role of carvedilol in the management of portal hypertension.
Topics: Antihypertensive Agents; Ascites; Benzopyrans; Carbazoles; Carvedilol; Drug Therapy, Combination; Ethanolamines; Hemodynamics; Humans; Hypertension, Portal; Multicenter Studies as Topic; Nebivolol; Nitrates; Propanolamines; Propranolol; Randomized Controlled Trials as Topic | 2010 |
Systematic review with meta-analysis: the haemodynamic effects of carvedilol compared with propranolol for portal hypertension in cirrhosis.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Hemodynamics; Hepatic Veins; Humans; Hypertension, Portal; Liver Cirrhosis; Propanolamines; Propranolol | 2014 |
Beta-blockers for congestive heart failure in children.
Topics: Adolescent; Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Child; Child, Preschool; Heart Failure; Humans; Infant; Infant, Newborn; Metoprolol; Propanolamines; Propranolol; Randomized Controlled Trials as Topic | 2016 |
Carvedilol for portal hypertension in cirrhosis: systematic review with meta-analysis.
Topics: Antihypertensive Agents; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Hemodynamics; Humans; Hypertension, Portal; Liver Cirrhosis; Propanolamines; Propranolol; Treatment Outcome | 2016 |
Pharmacologic prevention of variceal bleeding and rebleeding.
Topics: Adrenergic beta-Antagonists; Atorvastatin; Carbazoles; Carvedilol; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Hemodynamics; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Portal; Incidence; Liver; Liver Cirrhosis; Nitric Oxide Synthase Type III; Portal Pressure; Propanolamines; Propranolol; Simvastatin; Splanchnic Circulation | 2018 |
[Management of compensated liver cirrhosis 2018 - Evidence based prophylactic measures].
Topics: Carvedilol; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Germany; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Propranolol | 2018 |
Outcomes of beta blocker use in cocaine-associated chest pain: a meta-analysis.
Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Atenolol; Bisoprolol; Carvedilol; Cocaine; Humans; Metoprolol; Propanolamines; Propranolol | 2018 |
Carvedilol versus traditional, non-selective beta-blockers for adults with cirrhosis and gastroesophageal varices.
Topics: Adrenergic beta-Antagonists; Adult; Carvedilol; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Liver Cirrhosis; Nadolol; Primary Prevention; Propranolol; Randomized Controlled Trials as Topic; Secondary Prevention | 2018 |
Pharmacologic Management of Portal Hypertension.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-Antagonists; Anticoagulants; Antihypertensive Agents; Carvedilol; Esophageal and Gastric Varices; Gastrointestinal Agents; Gastrointestinal Hemorrhage; Hemostasis, Endoscopic; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Portal; Nitrates; Octreotide; Propranolol; Somatostatin; Terlipressin; Vasodilator Agents | 2019 |
Use of beta-blockers for rosacea-associated facial erythema and flushing: A systematic review and update on proposed mode of action.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Bradycardia; Carvedilol; Dermatologic Agents; Drug Evaluation; Erythema; Facial Dermatoses; Flushing; Humans; Hypotension; Nadolol; Propranolol; Retrospective Studies; Rosacea; Treatment Outcome | 2020 |
Beta-blockers for congestive heart failure in children.
Topics: Adolescent; Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Child; Child, Preschool; Heart Failure; Heart Transplantation; Humans; Infant; Infant, Newborn; Metoprolol; Propanolamines; Propranolol; Randomized Controlled Trials as Topic; Stroke Volume | 2020 |
Carvedilol as the new non-selective beta-blocker of choice in patients with cirrhosis and portal hypertension.
Topics: Adrenergic beta-Antagonists; Ascites; Carvedilol; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal; Liver Cirrhosis; Propranolol | 2023 |
Diagnosis and Management of Cirrhosis and Its Complications: A Review.
Topics: Adult; Ascites; Carvedilol; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Hepatic Encephalopathy; Hepatorenal Syndrome; Humans; Lactulose; Liver Cirrhosis; Liver Neoplasms; Male; Muscle Cramp; Propranolol; Randomized Controlled Trials as Topic; Sodium Potassium Chloride Symporter Inhibitors; Terlipressin; United States | 2023 |
36 trial(s) available for carvedilol and propranolol
| Article | Year |
|---|---|
Acute hemodynamic effects of carvedilol in comparison with propranolol in patients with coronary heart disease.
Topics: Adrenergic beta-Antagonists; Adult; Angioplasty, Balloon, Coronary; Antihypertensive Agents; Carbazoles; Carvedilol; Combined Modality Therapy; Coronary Disease; Double-Blind Method; Exercise Test; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Propanolamines; Propranolol; Vasodilator Agents | 1992 |
A comparison of carvedilol with a combination of propranolol and isosorbide dinitrate in the chronic treatment of stable angina.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Antihypertensive Agents; Blood Pressure; Carbazoles; Carvedilol; Double-Blind Method; Drug Therapy, Combination; Exercise Test; Heart Rate; Humans; Isosorbide Dinitrate; Male; Propanolamines; Propranolol; Random Allocation | 1992 |
Myocardial protection with carvedilol.
Topics: Adrenergic beta-Antagonists; Animals; Carbazoles; Carvedilol; Coronary Disease; Dogs; Heart; Injections, Intravenous; Male; Myocardial Infarction; Myocardial Reperfusion; Propanolamines; Propranolol; Rats; Rats, Inbred Strains; Swine; Vasodilator Agents | 1992 |
Blood pressure lowering and cerebral blood flow: a comparison of the effects of carvedilol and propranolol on the cerebral circulation in hypertensive patients.
Topics: Adolescent; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Carbazoles; Carvedilol; Cerebrovascular Circulation; Double-Blind Method; Heart Rate; Humans; Hypertension; Middle Aged; Propanolamines; Propranolol | 1992 |
[Neither propranolol nor the vasodilating beta-blocker carvedilol have a direct effect on coronary resistance vessels].
Topics: Adrenergic beta-Antagonists; Blood Flow Velocity; Blood Pressure; Carbazoles; Carvedilol; Coronary Angiography; Coronary Circulation; Coronary Disease; Heart Rate; Humans; Propanolamines; Propranolol; Vascular Resistance; Vasodilator Agents | 1991 |
Influence of carvedilol and propranolol on coronary blood flow.
Topics: Adrenergic beta-Antagonists; Blood Pressure; Carbazoles; Carvedilol; Coronary Circulation; Coronary Disease; Double-Blind Method; Heart Rate; Humans; Male; Middle Aged; Myocardium; Oxygen Consumption; Propanolamines; Propranolol; Randomized Controlled Trials as Topic; Vascular Resistance | 1990 |
Acute hemodynamic effects of the vasodilating and beta-blocking agent carvedilol in comparison to propranolol.
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Carbazoles; Carvedilol; Coronary Disease; Double-Blind Method; Heart Rate; Hemodynamics; Humans; Leg; Male; Middle Aged; Physical Exertion; Propanolamines; Propranolol; Pulmonary Wedge Pressure; Random Allocation; Vascular Resistance | 1987 |
Haemodynamics of carvedilol in normal subjects compared with propranolol, pindolol, and labetalol.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Blood Pressure; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; Double-Blind Method; Heart Rate; Hemodynamics; Humans; Labetalol; Male; Physical Exertion; Pindolol; Propanolamines; Propranolol; Random Allocation | 1987 |
[The acute hemodynamic effects of the new vasodilating beta blocker carvedilol in comparison with combined administration of nifedipine and propranolol in patients with coronary heart disease].
Topics: Carbazoles; Carvedilol; Coronary Circulation; Coronary Disease; Drug Therapy, Combination; Female; Hemodynamics; Humans; Infusions, Intravenous; Male; Middle Aged; Myocardial Infarction; Nifedipine; Propanolamines; Propranolol; Vasodilator Agents | 1989 |
Vasodilating mechanism and response to physiological pressor stimuli of acute doses of carvedilol compared with labetalol, propranolol and hydralazine.
Topics: Adrenergic beta-Antagonists; Adult; Angiotensin II; Antihypertensive Agents; Blood Pressure; Carbazoles; Carvedilol; Cold Temperature; Double-Blind Method; Exercise; Heart Rate; Hemodynamics; Humans; Hydralazine; Isoproterenol; Labetalol; Male; Middle Aged; Phenylephrine; Posture; Propanolamines; Propranolol; Vasodilator Agents | 1988 |
Beta-adrenoceptor blockade and vasodilatation in essential hypertension. Hemodynamic studies at rest and during exposure to stress.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Carbazoles; Carvedilol; Clinical Trials as Topic; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hydralazine; Hypertension; Male; Middle Aged; Noise; Propanolamines; Propranolol; Pyridazines; Stress, Physiological; Time Factors; Vasodilator Agents | 1984 |
Reproducibility and consistency of the responses to supine bicycle ergometry; evaluation in conjunction with beta 1-adrenoceptor occupancies.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Blood Pressure; Carbazoles; Carvedilol; Celiprolol; Epinephrine; Exercise Test; Heart Rate; Humans; Male; Metoprolol; Norepinephrine; Propanolamines; Propranolol; Radioligand Assay; Receptors, Adrenergic, beta; Reproducibility of Results | 1994 |
Dose-effect and pharmacokinetic-pharmacodynamic relationships of the beta 1-adrenergic receptor blocking properties of various doses of carvedilol in healthy humans.
Topics: Administration, Oral; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Analysis of Variance; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; Hemodynamics; Humans; Male; Propanolamines; Propranolol; Radioligand Assay; Receptors, Adrenergic; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta-1; Reference Values; Stereoisomerism; Time Factors | 1994 |
Nonselective beta-adrenergic blockade with carvedilol does not hinder the benefits of exercise training in patients with congestive heart failure.
Topics: Adaptation, Physiological; Adrenergic beta-Antagonists; Aerobiosis; Aged; Angiotensin-Converting Enzyme Inhibitors; Carbazoles; Cardiotonic Agents; Carvedilol; Digoxin; Diuretics; Drug Therapy, Combination; Exercise Therapy; Female; Forearm; Furosemide; Heart; Heart Failure; Humans; Hyperemia; Leg; Male; Middle Aged; Oxygen Consumption; Propanolamines; Propranolol; Receptors, Adrenergic, beta | 1997 |
Influence of beta-blockers on melatonin release.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Carbazoles; Carvedilol; Circadian Rhythm; Cross-Over Studies; Double-Blind Method; Hemodynamics; Humans; Male; Melatonin; Propanolamines; Propranolol; Stereoisomerism; Verapamil | 1999 |
Carvedilol, a new nonselective beta-blocker with intrinsic anti- Alpha1-adrenergic activity, has a greater portal hypotensive effect than propranolol in patients with cirrhosis.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Carbazoles; Carvedilol; Esophageal and Gastric Varices; Female; Heart Rate; Hemodynamics; Humans; Hypertension, Portal; Liver Cirrhosis; Male; Middle Aged; Placebos; Portal Pressure; Propanolamines; Propranolol; Vascular Resistance | 1999 |
[Antioxidant and antiarrhythmic activity of carvedilol in patients with ischemic heart disease. Comparison with anaprilin].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Anti-Arrhythmia Agents; Antioxidants; Arrhythmias, Cardiac; Carbazoles; Carvedilol; Electrocardiography; Heart Rate; Humans; Lipid Peroxidation; Male; Middle Aged; Myocardial Infarction; Placebos; Propanolamines; Propranolol; Sclerosis; Single-Blind Method; Ventricular Dysfunction, Left | 2001 |
[Clinical and hemodynamic effects of anaprilin and carvedilol in patients with coronary heart disease].
Topics: Carbazoles; Carvedilol; Cross-Over Studies; Hemodynamics; Humans; Myocardial Ischemia; Propanolamines; Propranolol; Vasodilator Agents | 2001 |
Acute and 7-day portal pressure response to carvedilol and propranolol in cirrhotics.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Carbazoles; Carvedilol; Double-Blind Method; Esophageal and Gastric Varices; Female; Hepatic Veins; Humans; Hypertension, Portal; Liver Cirrhosis; Male; Middle Aged; Portal Pressure; Propanolamines; Propranolol; Risk Factors; Venous Pressure | 2002 |
Randomized comparison of long-term carvedilol and propranolol administration in the treatment of portal hypertension in cirrhosis.
Topics: Antihypertensive Agents; Carbazoles; Carvedilol; Drug Therapy, Combination; Female; Humans; Hypertension, Portal; Kidney; Liver Circulation; Liver Cirrhosis; Male; Middle Aged; Propanolamines; Propranolol; Splanchnic Circulation | 2002 |
[Status of microcirculation and cardiodynamics in ischemic heart disease patients with decreased left ventricular fraction and their response to carvedilol].
Topics: Carbazoles; Carvedilol; Cross-Over Studies; Heart; Humans; Microcirculation; Myocardial Ischemia; Propanolamines; Propranolol; Skin; Ventricular Function, Left | 2002 |
[Contribution of antioxidant properties of carvedilol in its effect on cardiac remodeling in patients with ischemic heart disease with incipient heart failure].
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Antioxidants; Carbazoles; Carvedilol; Cross-Over Studies; Data Interpretation, Statistical; Echocardiography; Heart Failure; Hemodynamics; Humans; Lipid Peroxidation; Male; Middle Aged; Myocardial Ischemia; Placebos; Propanolamines; Propranolol; Time Factors | 2003 |
Effects of carvedilol on oxidative stress in polymorphonuclear and mononuclear cells in patients with essential hypertension.
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Biomarkers; Blood Pressure; C-Reactive Protein; Carbazoles; Carvedilol; Cholesterol, HDL; Cholesterol, LDL; Female; Glycated Hemoglobin; Humans; Hypertension; Insulin; Japan; Leukocytes, Mononuclear; Male; Middle Aged; Neutrophils; Oxidative Stress; Propanolamines; Propranolol; Risk Factors; Statistics as Topic; Treatment Outcome; Triglycerides | 2004 |
Acute administration of carvedilol is more effective than propranolol plus isosorbide-5-mononitrate in the reduction of portal pressure in patients with viral cirrhosis.
Topics: Antihypertensive Agents; Carbazoles; Carvedilol; Drug Therapy, Combination; Female; Humans; Hypertension, Portal; Isosorbide Dinitrate; Liver Cirrhosis; Male; Middle Aged; Propanolamines; Propranolol; Vasodilator Agents | 2004 |
Effects of adrenoceptor blocking drugs on cardiovascular responsiveness to passive orthostasis: a placebo-controlled double-blind study.
Topics: Adrenergic alpha-Antagonists; Adrenergic Antagonists; Adrenergic beta-Antagonists; Adult; Carbazoles; Carvedilol; Dizziness; Double-Blind Method; Female; Hemodynamics; Humans; Male; Propanolamines; Propranolol; Sulfonamides; Tamsulosin; Time Factors | 2005 |
Carvedilol or propranolol in portal hypertension? A randomized comparison.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Double-Blind Method; Female; Hepatic Veins; Humans; Hypertension, Portal; Liver Cirrhosis; Male; Middle Aged; Portal Pressure; Predictive Value of Tests; Propanolamines; Propranolol; Treatment Outcome; Venous Pressure | 2012 |
The insulin like growth factor system in cirrhosis. Relation to changes in body composition following adrenoreceptor blockade.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Body Composition; Bone Density; Carbazoles; Carvedilol; Cross-Sectional Studies; Female; Follow-Up Studies; Humans; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Liver; Liver Cirrhosis; Male; Middle Aged; Propanolamines; Propranolol; Prospective Studies | 2012 |
Carvedilol for primary prophylaxis of variceal bleeding in cirrhotic patients with haemodynamic non-response to propranolol.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; Esophageal and Gastric Varices; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; Hemodynamics; Humans; Kaplan-Meier Estimate; Ligation; Liver Cirrhosis; Male; Middle Aged; Propanolamines; Propranolol; Treatment Failure; Treatment Outcome | 2013 |
Effects of carvedilol and propranolol on circulatory regulation and oxygenation in cirrhosis: a randomised study.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-Antagonists; Arteries; Blood Pressure; Blood Volume; Carbazoles; Cardiac Output; Carvedilol; Compliance; Female; Heart Rate; Hemodynamics; Humans; Hypertension, Portal; Liver Circulation; Liver Cirrhosis; Male; Middle Aged; Oximetry; Plasma Volume; Portal Pressure; Propanolamines; Propranolol; Renin; Treatment Outcome; Vascular Resistance | 2014 |
A Randomized, Multi-Center, Open-Label Study to Evaluate the Efficacy of Carvedilol vs. Propranolol to Reduce Portal Pressure in Patients With Liver Cirrhosis.
Topics: Adult; Antihypertensive Agents; Ascites; Carbazoles; Carvedilol; End Stage Liver Disease; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Hemodynamics; Hepatic Veins; Humans; Hypertension, Portal; Liver Cirrhosis; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Portal Pressure; Propanolamines; Propranolol; Severity of Illness Index; Treatment Outcome | 2016 |
Carvedilol versus propranolol effect on hepatic venous pressure gradient at 1 month in patients with index variceal bleed: RCT.
Topics: Adult; Antihypertensive Agents; Carbazoles; Carvedilol; Esophageal and Gastric Varices; Esophagoscopy; Female; Gastrointestinal Hemorrhage; Hepatic Veins; Humans; Male; Middle Aged; Portal Pressure; Propanolamines; Propranolol | 2017 |
Assessment of Haemodynamic Response to Nonselective Beta-Blockers in Portal Hypertension by Phase-Contrast Magnetic Resonance Angiography.
Topics: Adrenergic beta-Antagonists; Aged; Aorta, Abdominal; Carbazoles; Carvedilol; Contrast Media; Female; Hemodynamics; Humans; Hypertension, Portal; Magnetic Resonance Angiography; Male; Middle Aged; Propanolamines; Propranolol | 2017 |
Efficacy of carvedilol versus propranolol versus variceal band ligation for primary prevention of variceal bleeding.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Carbazoles; Carvedilol; Egypt; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Humans; Ligation; Male; Middle Aged; Propanolamines; Propranolol; Treatment Outcome | 2018 |
β blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aged; Ascites; Carvedilol; Double-Blind Method; Female; Gastrointestinal Hemorrhage; Hepatic Encephalopathy; Humans; Hypertension, Portal; Liver Cirrhosis; Male; Middle Aged; Proportional Hazards Models; Propranolol; Severity of Illness Index | 2019 |
Conversion of Propranolol to Carvedilol Improves Renal Perfusion and Outcome in Patients With Cirrhosis and Ascites.
Topics: Ascites; Carvedilol; Humans; Kidney; Liver Cirrhosis; Perfusion; Propranolol | 2021 |
Comparison of carvedilol and propranolol for primary prophylaxis of esophageal variceal bleed in cirrhotic patients.
Topics: Adrenergic beta-Antagonists; Carvedilol; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Liver Cirrhosis; Propranolol; Varicose Veins | 2023 |
101 other study(ies) available for carvedilol and propranolol
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors.
Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Algorithms; Animals; Cell Line; CHO Cells; Cricetinae; Dioxoles; Humans; Propanolamines; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3 | 2005 |
High-throughput log P determination by ultraperformance liquid chromatography: a convenient tool for medicinal chemists.
Topics: Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Chromatography, Liquid; Mathematics; Pharmaceutical Preparations; Software | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Metabolic soft spot identification and compound optimization in early discovery phases using MetaSite and LC-MS/MS validation.
Topics: Chromatography, Liquid; Drug Design; Humans; Likelihood Functions; Microsomes, Liver; Pharmacokinetics; Tandem Mass Spectrometry | 2009 |
Lipophilicity of basic drugs measured by hydrophilic interaction chromatography.
Topics: Chemistry, Pharmaceutical; Chromatography; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Pharmaceutical Preparations; Solubility; Technology, Pharmaceutical | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Synthesis and adrenolytic activity of 1-(1H-indol-4-yloxy)-3-(2-(2-methoxy phenoxy)ethylamino)propan-2-ol analogs and its enantiomers. Part 2.
Topics: 2-Propanol; Adrenergic Antagonists; Animals; Antihypertensive Agents; Carbazoles; Carvedilol; Ileum; Male; Molecular Structure; Propanolamines; Rabbits; Rats; Rats, Wistar; Stereoisomerism | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Synthesis and preliminary evaluation of pharmacological properties of some piperazine derivatives of xanthone.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Heart Rate; Male; Piperazine; Piperazines; Protein Binding; Rats; Rats, Wistar; Receptors, Adrenergic; Stereoisomerism; Xanthones | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Design, synthesis and cardiovascular evaluation of some aminoisopropanoloxy derivatives of xanthone.
Topics: Adrenergic Antagonists; Animals; Blood Pressure; Calcium Channel Blockers; Calcium Channels; Drug Design; Heart Rate; Inhibitory Concentration 50; Male; Platelet Aggregation; Radioligand Assay; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Structure-Activity Relationship; Verapamil; Xanthones | 2018 |
Design, Synthesis, and Biological Evaluation of a New Series of Carvedilol Derivatives That Protect Sensory Hair Cells from Aminoglycoside-Induced Damage by Blocking the Mechanoelectrical Transducer Channel.
Topics: Aminoglycosides; Animals; Carvedilol; Chemistry Techniques, Synthetic; Cytoprotection; Dose-Response Relationship, Drug; Drug Design; Electrophysiological Phenomena; Hair Cells, Auditory; Mechanotransduction, Cellular; Mice; Zebrafish | 2019 |
Drug repurposing and rediscovery: Design, synthesis and preliminary biological evaluation of 1-arylamino-3-aryloxypropan-2-ols as anti-melanoma agents.
Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Discovery; Drug Repositioning; Drug Screening Assays, Antitumor; Humans; Melanoma; Molecular Docking Simulation; Molecular Structure; Propanols; Skin Neoplasms; Structure-Activity Relationship; Tumor Cells, Cultured | 2020 |
Cardioprotective effects of carvedilol, a novel beta adrenoceptor antagonist with vasodilating properties, in anaesthetised minipigs: comparison with propranolol.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Carbazoles; Carvedilol; Disease Models, Animal; Heart Rate; Myocardial Infarction; Myocardium; Peroxidase; Propanolamines; Propranolol; Swine; Swine, Miniature; Vasodilator Agents | 1992 |
Single and repeated doses of the vasodilator/beta-adrenergic antagonist, carvedilol, block cirazoline- and isoproterenol-mediated hemodynamic responses in the conscious rat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Carbazoles; Carvedilol; Hemodynamics; Imidazoles; Isoproterenol; Male; Prazosin; Propanolamines; Propranolol; Rats; Rats, Sprague-Dawley; Time Factors; Vasodilator Agents | 1992 |
Receptor pharmacology of carvedilol in the human heart.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Binding, Competitive; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Cyclic AMP; Guanylyl Imidodiphosphate; Humans; Iodocyanopindolol; Metoprolol; Myocardium; Pindolol; Propanolamines; Propranolol; Receptors, Adrenergic, beta; Vasodilator Agents | 1992 |
Adrenoceptor-blocking activity and cardiohemodynamic effects of carvedilol in animals.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Aorta, Thoracic; Carbazoles; Carvedilol; Coronary Circulation; Dogs; Female; Guinea Pigs; Heart; Heart Rate; Hemodynamics; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Oxygen Consumption; Propanolamines; Propranolol; Rats; Trachea | 1990 |
Comparison of the effects of carvedilol, propranolol, and verapamil on in vitro platelet function in healthy volunteers.
Topics: Adrenergic beta-Antagonists; Blood Platelets; Carbazoles; Carvedilol; Coronary Disease; Cyclic AMP; Humans; In Vitro Techniques; Platelet Aggregation; Platelet Aggregation Inhibitors; Propanolamines; Propranolol; Thromboxane B2; Vasodilator Agents; Verapamil | 1991 |
General pharmacological profiles of the new beta-adrenoceptor antagonist carvedilol.
Topics: Adrenergic beta-Antagonists; Animals; Anticonvulsants; Autonomic Nervous System; Behavior, Animal; Body Temperature; Carbazoles; Carvedilol; Electroencephalography; Hemodynamics; Male; Mice; Mice, Inbred Strains; Muscle Contraction; Muscle, Smooth; Muscles; Propanolamines; Propranolol; Reflex; Respiration; Sleep | 1990 |
Norepinephrine-induced changes in rat heart function, metabolism, and weight are antagonized by carvedilol.
Topics: Adrenergic beta-Antagonists; Animals; Body Weight; Carbazoles; Carvedilol; Female; Glucosephosphate Dehydrogenase; Heart; Heart Rate; Infusions, Intravenous; Myocardial Contraction; Myocardium; Norepinephrine; Prazosin; Propanolamines; Propranolol; Rats; Rats, Sprague-Dawley | 1993 |
Cardioprotective potential of carvedilol.
Topics: Adrenergic beta-Antagonists; Animals; Carbazoles; Carvedilol; Diltiazem; Dogs; Free Radical Scavengers; Male; Myocardial Infarction; Propanolamines; Propranolol; Rats; Rats, Sprague-Dawley; Swine; Swine, Miniature; Vasodilator Agents | 1993 |
Carvedilol protects against lethal reperfusion injury through antiadrenergic mechanisms.
Topics: Adrenergic Antagonists; Animals; Carbazoles; Carvedilol; Cats; Doxazosin; Free Radical Scavengers; Glutathione; Heart; Hemodynamics; Male; Myocardial Reperfusion Injury; Myocardium; Propanolamines; Propranolol; Thiobarbituric Acid Reactive Substances | 1996 |
Chronic carvedilol reduces mortality and renal damage in hypertensive stroke-prone rats.
Topics: Adrenergic beta-Antagonists; Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Carbazoles; Carvedilol; Heart Rate; Hypertension; Kidney; Male; Propanolamines; Propranolol; Rabbits; Rats; Rats, Inbred SHR; Renin | 1996 |
Carvedilol and its metabolites suppress endothelin-1 production in human endothelial cell culture.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Ascorbic Acid; Calcium Channel Blockers; Carbazoles; Carvedilol; Cells, Cultured; Endothelin-1; Endothelium, Vascular; Humans; Metoprolol; Nicardipine; Prazosin; Probucol; Propanolamines; Propranolol; Umbilical Veins | 1997 |
Effects of chronic treatment with carvedilol on smooth muscle tone and endothelium-dependent relaxation of aorta in stroke-prone spontaneously hypertensive rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Carbazoles; Carvedilol; Endothelium, Vascular; Muscle Relaxation; Muscle Tonus; Muscle, Smooth, Vascular; Norepinephrine; Potassium; Propanolamines; Propranolol; Rats; Rats, Inbred SHR | 1997 |
Carvedilol protects against glomerulosclerosis in rat remnant kidney without general changes in antioxidant enzyme status. A comparative study of two beta-blocking drugs, carvedilol and propanolol.
Topics: Adrenergic beta-Antagonists; Aldehydes; Animals; Antioxidants; Blood Pressure; Carbazoles; Carvedilol; Free Radical Scavengers; Glomerulosclerosis, Focal Segmental; Hydrogen Peroxide; Kidney Cortex; Kidney Failure, Chronic; Lipid Peroxidation; Male; Malondialdehyde; Nephrectomy; Propanolamines; Propranolol; Rats; Rats, Wistar | 1997 |
Comparison of metoprolol and carvedilol pharmacology and cardioprotection in rabbit ischemia and reperfusion model.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Antioxidants; Blood Pressure; Carbazoles; Carvedilol; Heart Rate; Male; Metoprolol; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Oxidation-Reduction; Peroxidase; Propanolamines; Propranolol; Rabbits; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Recombinant Proteins; Solubility; Ventricular Function, Left; Ventricular Pressure | 1998 |
Carvedilol--A new nonselective beta blocker.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Hemodynamics; Humans; Hypotension; Liver Cirrhosis; Propanolamines; Propranolol; Vasodilator Agents | 2000 |
Carvedilol stimulates nitric oxide synthesis in rat cardiac myocytes.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Animals, Newborn; Atenolol; Carbazoles; Carvedilol; Dactinomycin; Drug Synergism; Enzyme Induction; Enzyme Inhibitors; Guanidines; Heart; Interleukin-1; Isoproterenol; Muscle Proteins; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Nucleic Acid Synthesis Inhibitors; Propanolamines; Propranolol; Rats; Rats, Sprague-Dawley; Recombinant Proteins | 2000 |
An advance in the treatment of portal hypertension?
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Humans; Hypertension, Portal; Liver Cirrhosis; Propanolamines; Propranolol | 2000 |
Beta-blockade in adriamycin-induced cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antineoplastic Agents; Carbazoles; Cardiomyopathies; Cardiomyopathy, Dilated; Carvedilol; Doxorubicin; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Contraction; Neoplasms; Propanolamines; Propranolol; Retrospective Studies; Stroke Volume | 2000 |
Reduction of oxidative stress by carvedilol: role in maintenance of ischaemic myocardium viability.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Antioxidants; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; Male; Myocardial Reperfusion Injury; Myocardium; Oxidative Stress; Perfusion; Phosphocreatine; Propanolamines; Propranolol; Rabbits; Random Allocation | 2000 |
Selective or nonselective beta-adrenergic blockade in patients with congestive heart failure.
Topics: Adrenergic beta-Antagonists; Animals; Carbazoles; Carvedilol; Heart Failure; Hemodynamics; Humans; Metoprolol; Prognosis; Propanolamines; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Vasoconstriction | 2000 |
The inhibitory effects of carvedilol against arrhythmias induced by coronary reperfusion in anesthetized rats.
Topics: Adrenergic beta-Antagonists; Anesthesia, General; Animals; Arrhythmias, Cardiac; Carbazoles; Carvedilol; Catalase; Dose-Response Relationship, Drug; Male; Myocardial Reperfusion Injury; Propanolamines; Propranolol; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2000 |
Effect of carvedilol on atrioventricular conduction in the ischemic heart.
Topics: Action Potentials; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Bundle of His; Carbazoles; Carvedilol; Guinea Pigs; Male; Myocardial Ischemia; Papillary Muscles; Prazosin; Propanolamines; Propranolol; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2001 |
Effects of nebivolol on human platelet aggregation.
Topics: Adenosine Diphosphate; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Arginine; Benzopyrans; Blood Platelets; Carbazoles; Carvedilol; Collagen; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Ethanolamines; Humans; Male; Nebivolol; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Aggregation; Platelet Aggregation Inhibitors; Propanolamines; Propranolol; Vasodilator Agents | 2001 |
Synthesis and evaluation of radiolabeled antagonists for imaging of beta-adrenoceptors in the brain with PET.
Topics: Adrenergic beta-Antagonists; Animals; Brain; Bupranolol; Carbazoles; Carbon Radioisotopes; Carvedilol; Fluorine Radioisotopes; Male; Models, Animal; Organ Specificity; Pindolol; Propanolamines; Propranolol; Radioligand Assay; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Tissue Distribution; Tomography, Emission-Computed | 2002 |
Different effects of carvedilol, metoprolol, and propranolol on left ventricular remodeling after coronary stenosis or after permanent coronary occlusion in rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Ascorbic Acid; Carbazoles; Cardiac Catheterization; Carvedilol; Coronary Disease; Coronary Stenosis; Disease Models, Animal; Dose-Response Relationship, Drug; Echocardiography; Hemodynamics; Male; Metoprolol; Norepinephrine; Propanolamines; Propranolol; Quinazolines; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Stroke Volume; Survival Rate; Thiobarbituric Acid Reactive Substances; Ventricular Function, Left; Ventricular Remodeling | 2002 |
[A comparative study of anapriline and carvedilol effectiveness in patients with thyrotoxicosis in pre- and postoperative periods].
Topics: Adrenergic beta-Antagonists; Adult; Carbazoles; Carvedilol; Female; Humans; Hyperthyroidism; Hypertrophy, Left Ventricular; Male; Middle Aged; Postoperative Care; Preoperative Care; Propanolamines; Propranolol | 2002 |
Effect of beta blockers on new congestive heart failure in older persons with healed myocardial infarcts.
Topics: Adrenergic beta-Antagonists; Aged; Carbazoles; Carvedilol; Heart Failure; Humans; Myocardial Infarction; Propanolamines; Propranolol | 2002 |
Antiplatelet activity of carvedilol in comparison to propranolol.
Topics: Adenosine Diphosphate; Calcimycin; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; In Vitro Techniques; Platelet Aggregation; Platelet Aggregation Inhibitors; Propanolamines; Propranolol; Reference Values; Tetradecanoylphorbol Acetate | 2002 |
Carvedilol increases the production of interleukin-12 and interferon-gamma and improves the survival of mice infected with the encephalomyocarditis virus.
Topics: Adrenergic beta-Antagonists; Animals; Carbazoles; Cardiovirus Infections; Carvedilol; Dose-Response Relationship, Drug; Encephalomyocarditis virus; Interferon-gamma; Interleukin-12; Male; Metoprolol; Mice; Mice, Inbred DBA; Myocarditis; Propanolamines; Propranolol; Survival Rate | 2003 |
Management of drug and alcohol withdrawal.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Cocaine; Humans; Propanolamines; Propranolol; Substance Withdrawal Syndrome | 2003 |
Cardioprotective effects of carvedilol on acute autoimmune myocarditis: anti-inflammatory effects associated with antioxidant property.
Topics: Acute Disease; Adrenergic beta-Antagonists; Animals; Anti-Inflammatory Agents; Antioxidants; Autoimmune Diseases; Blood Pressure; Body Weight; Carbazoles; Cardiotonic Agents; Carvedilol; Heart Rate; Metoprolol; Myocarditis; Myocardium; Nuclease Protection Assays; Organ Size; Propanolamines; Propranolol; Rats; Ribonucleases; Thiobarbituric Acid Reactive Substances | 2004 |
Cardioprotective effects of carvedilol on acute autoimmune myocarditis.
Topics: Administration, Oral; Animals; Autoimmune Diseases; Carbazoles; Cardiotonic Agents; Carvedilol; Dose-Response Relationship, Drug; Metoprolol; Myocarditis; Myocardium; Myosins; Propanolamines; Propranolol; Proteins; Rats; Rats, Inbred Lew; Thiobarbituric Acid Reactive Substances | 2004 |
Beta-adrenoceptor blocker carvedilol provides cardioprotection via an adenosine-dependent mechanism in ischemic canine hearts.
Topics: 5'-Nucleotidase; Adenosine; Adrenergic beta-Antagonists; Animals; Carbazoles; Carvedilol; Cells, Cultured; Coronary Circulation; Dogs; Humans; Myocardial Infarction; Myocardial Ischemia; Myocardium; Oxidative Stress; Propanolamines; Propranolol | 2004 |
Advantages in the use of carvedilol versus propranolol for the protection of cardiac mitochondrial function.
Topics: Animals; Carbazoles; Carvedilol; Intracellular Membranes; Male; Mitochondria, Heart; Permeability; Propanolamines; Propranolol; Rats; Rats, Wistar | 2004 |
Carvedilol--a beta-blocker with considerable antiaggregatory effect on human blood platelets.
Topics: Adrenergic beta-Antagonists; Atenolol; Carbazoles; Carvedilol; Humans; In Vitro Techniques; Platelet Aggregation; Platelet Aggregation Inhibitors; Propanolamines; Propranolol; Thromboxane B2 | 2005 |
Carvedilol blocks beta2- more than beta1-adrenoceptors in human heart.
Topics: Adrenergic beta-Antagonists; Calcium Channels, L-Type; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; Epinephrine; Heart Atria; Heart Failure; Heart Ventricles; Humans; Imidazoles; In Vitro Techniques; Metoprolol; Myocardial Contraction; Myocardium; Norepinephrine; Patch-Clamp Techniques; Propanolamines; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2 | 2006 |
Comparison of HERG channel blocking effects of various beta-blockers-- implication for clinical strategy.
Topics: Adrenergic beta-Antagonists; Binding Sites; Carbazoles; Cardiovascular Diseases; Carvedilol; Cell Line; Dose-Response Relationship, Drug; Ether-A-Go-Go Potassium Channels; Humans; Long QT Syndrome; Membrane Potentials; Metoprolol; Mutation; Potassium Channel Blockers; Propanolamines; Propranolol; Protein Binding; Transfection | 2006 |
Characterization of beta-adrenoceptor antagonists as substrates and inhibitors of the drug transporter P-glycoprotein.
Topics: Adrenergic beta-Antagonists; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bisoprolol; Caco-2 Cells; Carbazoles; Carvedilol; Cyclosporins; Digoxin; Dose-Response Relationship, Drug; Drug Interactions; Humans; Propanolamines; Propranolol; Time Factors | 2006 |
Beta-adrenoreceptor antagonists attenuate brain injury after transient focal ischemia in rats.
Topics: Adrenergic beta-Antagonists; Anesthesia; Anesthetics, Inhalation; Animals; Brain; Carbazoles; Carvedilol; Halothane; Ischemic Attack, Transient; Male; Morpholines; Myocardial Infarction; Propanolamines; Propranolol; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Urea | 2006 |
Influence of beta-adrenoceptor blockade on the myocardial accumulation of fatty acid tracer and its intracellular metabolism in the heart after ischemia-reperfusion injury.
Topics: Adrenergic beta-Antagonists; Animals; Autoradiography; Carbazoles; Carvedilol; Fatty Acids; Iodobenzenes; Male; Myocardial Ischemia; Myocardium; Oxidation-Reduction; Propanolamines; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Reperfusion Injury | 2006 |
Simultaneous determination of ten antiarrhythic drugs and a metabolite in human plasma by liquid chromatography--tandem mass spectrometry.
Topics: Amiodarone; Anti-Arrhythmia Agents; Atenolol; Bisoprolol; Carbazoles; Carvedilol; Chromatography, Liquid; Diltiazem; Humans; Metoprolol; Mexiletine; Molecular Structure; Propanolamines; Propranolol; Reproducibility of Results; Sotalol; Tandem Mass Spectrometry; Verapamil | 2007 |
Comparative effectiveness of carvedilol and propranolol on glycemic control and insulin resistance associated with L-thyroxin-induced hyperthyroidism--an experimental study.
Topics: Adrenergic beta-Antagonists; Animals; Appetite; Blood Glucose; Blood Pressure; Body Mass Index; Body Temperature; Carbazoles; Carvedilol; Cholesterol; Fasting; Female; Heart Rate; Hyperglycemia; Hyperinsulinism; Hyperthyroidism; Insulin; Insulin Resistance; Propanolamines; Propranolol; Rats; Rats, Wistar; Thyrotropin; Thyroxine; Triglycerides; Triiodothyronine | 2007 |
Blockade of adrenoreceptors inhibits the splenic response to stroke.
Topics: Adrenergic alpha-Antagonists; Adrenergic Antagonists; Adrenergic beta-Antagonists; Animals; Carbazoles; Carvedilol; Cytokines; Denervation; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Fetal Blood; Flow Cytometry; Humans; Infarction, Middle Cerebral Artery; Male; Propanolamines; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Spleen; Tyrosine 3-Monooxygenase | 2009 |
Molecular determinants of local anesthetic action of beta-blocking drugs: Implications for therapeutic management of long QT syndrome variant 3.
Topics: Adrenergic beta-Antagonists; Anesthetics, Local; Carbazoles; Carvedilol; Cell Line; Electrophysiology; Heart; Humans; Long QT Syndrome; Metoprolol; Propanolamines; Propranolol; Sodium Channels | 2010 |
Interaction of beta-blockers with the renal uptake transporter OCT2.
Topics: Adrenergic beta-Antagonists; Biological Transport; Bisoprolol; Carbazoles; Carvedilol; Cell Line; Humans; Kidney; Metformin; Metoprolol; Organic Cation Transport Proteins; Organic Cation Transporter 2; Propanolamines; Propranolol | 2009 |
Replacement of carvedilol for propranolol in patients with heart failure.
Topics: Adrenergic beta-Antagonists; Adult; Carbazoles; Carvedilol; Drug Substitution; Echocardiography; Follow-Up Studies; Heart Failure; Humans; Male; Middle Aged; Propanolamines; Propranolol; Prospective Studies; Treatment Outcome; Ventricular Function, Left | 2010 |
Is overall blockade superior to selective blockade of adrenergic receptor subtypes in suppressing left ventricular remodeling in spontaneously hypertensive rats?
Topics: Adrenergic Antagonists; Animals; Apoptosis; Bisoprolol; Blood Pressure; Carbazoles; Carvedilol; Disease Models, Animal; Heart Rate; Humans; Hypertension; Myocytes, Cardiac; Propanolamines; Propranolol; Rats; Rats, Inbred SHR; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta; Ventricular Remodeling | 2010 |
Combined blockade of β- and α₁-adrenoceptors in left ventricular remodeling induced by hypertension: beneficial or not?
Topics: Adrenergic Antagonists; Animals; Bisoprolol; Carbazoles; Carvedilol; Disease Models, Animal; Humans; Hypertension; Propanolamines; Propranolol; Rats; Rats, Inbred SHR; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta; Ventricular Remodeling | 2010 |
{Beta}-blocker drugs mediate calcium signaling in native central nervous system neurons by {beta}-arrestin-biased agonism.
Topics: Adrenergic beta-Antagonists; Animals; Arrestins; beta-Arrestin 2; beta-Arrestins; Calcium Signaling; Carbazoles; Carvedilol; Central Nervous System; Hippocampus; Mitogen-Activated Protein Kinase 3; Neurons; Propanolamines; Propranolol; Rats; Receptors, G-Protein-Coupled | 2010 |
1H and 13C NMR characteristics of β-blockers.
Topics: Acebutolol; Acids; Adrenergic beta-Antagonists; Alkalies; Alprenolol; Atenolol; Carbazoles; Carbon Isotopes; Carvedilol; Nuclear Magnetic Resonance, Biomolecular; Pindolol; Propanolamines; Propranolol; Protons; Timolol | 2011 |
Non-selective β-blockers improve the correlation of liver stiffness and portal pressure in advanced cirrhosis.
Topics: Adrenergic beta-Antagonists; Adult; Carbazoles; Carvedilol; Elasticity; Elasticity Imaging Techniques; Esophageal and Gastric Varices; Feasibility Studies; Female; Gastrointestinal Hemorrhage; Hemodynamics; Humans; Hypertension, Portal; Liver; Liver Cirrhosis; Male; Middle Aged; Portal Pressure; Propanolamines; Propranolol; Prospective Studies | 2012 |
Carvedilol suppresses fatty acid oxidation and stimulates glycolysis in C2C12 cells.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Bisoprolol; Carbazoles; Carvedilol; Cell Line; Epinephrine; Fatty Acids; Glycolysis; Mice; Oxidation-Reduction; Palmitic Acid; Prazosin; Propanolamines; Propranolol; Sympathomimetics | 2012 |
Carvedilol reduces the severity of atherosclerosis in apolipoprotein E-deficient mice via reducing superoxide production.
Topics: Adrenergic beta-Antagonists; Animals; Aorta; Apolipoproteins E; Atherosclerosis; Blood Pressure; Carbazoles; Carvedilol; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cholesterol, Dietary; Free Radicals; Heart Rate; Lipids; Macrophages; Male; Metoprolol; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Plaque, Atherosclerotic; Propanolamines; Propranolol; Superoxides | 2012 |
The renal effects of droxidopa are maintained in propranolol treated cirrhotic rats.
Topics: Adrenergic beta-Antagonists; Animals; Atorvastatin; Bilirubin; Carbazoles; Carvedilol; Creatinine; Droxidopa; Drug Evaluation, Preclinical; Drug Therapy, Combination; Hemodynamics; Heptanoic Acids; Liver Cirrhosis, Experimental; Mesenteric Artery, Superior; Osmolar Concentration; Portal Pressure; Potassium; Propanolamines; Propranolol; Pyrroles; Rats; Serum Albumin; Sodium; Vascular Resistance | 2015 |
Carvedilol protects against iron-induced microparticle generation and apoptosis of endothelial cells.
Topics: Adrenergic beta-Antagonists; Annexin A5; Apoptosis; Carbazoles; Carvedilol; Caspase 3; Cell-Derived Microparticles; Chlorides; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Ferric Compounds; Flow Cytometry; Human Umbilical Vein Endothelial Cells; Humans; Iron Chelating Agents; Iron Overload; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Oxidative Stress; Propanolamines; Propranolol; Reactive Oxygen Species | 2014 |
The influence of new beta-adrenolytics nebivolol and carvedilol on intraocular pressure and iris blood flow in rabbits.
Topics: Administration, Oral; Administration, Topical; Adrenergic beta-1 Receptor Antagonists; Animals; Antihypertensive Agents; Benzopyrans; Blood Flow Velocity; Carbazoles; Carvedilol; Ethanolamines; Female; Intraocular Pressure; Iris; Male; Nebivolol; Ophthalmic Solutions; Propanolamines; Propranolol; Rabbits; Regional Blood Flow; Tonometry, Ocular | 2014 |
Human and simulated intestinal fluids as solvent systems to explore food effects on intestinal solubility and permeability.
Topics: Animals; Atenolol; Body Fluids; Carbazoles; Carvedilol; Humans; Intestinal Secretions; Male; Metoprolol; Permeability; Propanolamines; Propranolol; Rats; Rats, Sprague-Dawley; Solubility; Solvents | 2014 |
Antiproliferative effects of β-blockers on human colorectal cancer cells.
Topics: Adenocarcinoma; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Atenolol; Carbazoles; Carvedilol; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Epinephrine; HT29 Cells; Humans; Isoproterenol; Norepinephrine; Propanolamines; Propranolol; Receptors, Adrenergic, beta; Signal Transduction | 2015 |
β-Arrestin-biased signaling mediates memory reconsolidation.
Topics: Alprenolol; Animals; Arrestins; beta-Arrestin 2; beta-Arrestins; Brain; Brain Mapping; Carbazoles; Carvedilol; Cocaine; Cyclic AMP-Dependent Protein Kinases; Extracellular Signal-Regulated MAP Kinases; Male; Maze Learning; Memory; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphorylation; Propanolamines; Propranolol; Receptors, Adrenergic, beta-1; Signal Transduction; Time Factors | 2015 |
β-Blockers have differential effects on the murine asthma phenotype.
Topics: Adrenergic beta-Antagonists; Allergens; Alprenolol; Animals; Asthma; Bronchoalveolar Lavage Fluid; Carbazoles; Carvedilol; Cell Count; Epinephrine; Female; Male; Mice, Knockout; Models, Biological; Mucins; Nadolol; Ovalbumin; Phenotype; Propanolamines; Propranolol | 2015 |
Vortex-assisted liquid-liquid extraction combined with field-amplified sample injection and sweeping micellar electrokinetic chromatography for improved determination of β-blockers in human urine.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Carbazoles; Carvedilol; Chromatography, Micellar Electrokinetic Capillary; Female; Humans; Liquid-Liquid Extraction; Propanolamines; Propranolol | 2016 |
Single-molecule imaging reveals the stoichiometry change of β2-adrenergic receptors by a pharmacological biased ligand.
Topics: Carbazoles; Carvedilol; Green Fluorescent Proteins; HEK293 Cells; Humans; Isoproterenol; Ligands; Microscopy, Fluorescence; Optical Imaging; Propanolamines; Propranolol; Receptors, Adrenergic, beta-2; Stereoisomerism | 2016 |
Determination of propranolol and carvedilol in urine samples using a magnetic polyamide composite and LC-MS/MS.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Limit of Detection; Magnetics; Microscopy, Electron, Scanning; Nylons; Osmolar Concentration; Propanolamines; Propranolol; Solid Phase Extraction; Tandem Mass Spectrometry; Urinalysis | 2016 |
Secondary prophylaxis for variceal bleeding: carvedilol vs. propranolol.
Topics: Adrenergic beta-Antagonists; Blood Pressure; Carbazoles; Carvedilol; Drug Monitoring; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal; Hypotension; Liver Cirrhosis; Outcome Assessment, Health Care; Propanolamines; Propranolol; Randomized Controlled Trials as Topic; Risk Assessment | 2017 |
Did Carvedilol Really Have More Severe Adverse Events than Propranolol in Cirrhotic Patients?
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Humans; Liver Cirrhosis; Propanolamines; Propranolol | 2017 |
Response to Lo et al.
Topics: Carbazoles; Carvedilol; Humans; Liver Cirrhosis; Propanolamines; Propranolol | 2017 |
The neuropeptide galanin promotes an anti-thrombotic phenotype on endocardial endothelial cells from heart failure patients.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Antithrombins; Carbazoles; Carvedilol; Cells, Cultured; Endothelial Cells; Galanin; Heart Failure; Heart Ventricles; Humans; Isoproterenol; Male; Middle Aged; Neuropeptide Y; Phenotype; Propanolamines; Propranolol; Protein Multimerization; Thrombin | 2017 |
Austrian consensus guidelines on the management and treatment of portal hypertension (Billroth III).
Topics: Austria; Carbazoles; Carvedilol; Comorbidity; Early Medical Intervention; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal; Liver Cirrhosis; Mass Screening; Propanolamines; Propranolol; Randomized Controlled Trials as Topic; Timolol | 2017 |
Metoprolol, propranolol, carvedilol, or labetalol for patients with Takotsubo syndrome?
Topics: Carvedilol; Humans; Labetalol; Metoprolol; Propranolol; Takotsubo Cardiomyopathy | 2018 |
Reply to: metoprolol, or propranolol, or carvedilol, or labetalol, for patients with takotsubo syndrome?
Topics: Carvedilol; Humans; Labetalol; Metoprolol; Propranolol; Takotsubo Cardiomyopathy | 2018 |
Primary prophylaxis of variceal bleeding.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Endoscopy; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Liver Cirrhosis; Nadolol; Propanolamines; Propranolol | 2018 |
β-blockers interfere with cell homing receptors and regulatory proteins in a model of spontaneously hypertensive rats.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Atenolol; beta-Arrestin 1; beta-Arrestin 2; Carbazoles; Carvedilol; Cell Movement; Chemokine CXCL12; Disease Models, Animal; G-Protein-Coupled Receptor Kinase 2; Hypertension; Kidney; Liver; Lung; Metoprolol; Myocardium; NF-kappa B; Propanolamines; Propranolol; Rats, Inbred SHR; Receptors, CXCR; Receptors, CXCR4; Signal Transduction | 2018 |
Effect of carvedilol versus propranolol on acute and chronic liver toxicity in rats.
Topics: Acetaminophen; Adrenergic beta-Antagonists; Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomarkers; Carbon Tetrachloride; Carvedilol; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Glutathione; Hepatic Stellate Cells; Liver; Liver Cirrhosis, Experimental; Male; Malondialdehyde; Oxidative Stress; Propranolol; Rats, Wistar; Tumor Necrosis Factor-alpha | 2021 |
Stimulation of β-adrenoceptors up-regulates cardiac expression of galectin-3 and BIM through the Hippo signalling pathway.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Bcl-2-Like Protein 11; Cardiovascular Diseases; Carvedilol; Cell Line; Dose-Response Relationship, Drug; Galectin 3; Isoproterenol; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Propanolamines; Propranolol; Rats; Receptors, Adrenergic, beta-3; Signal Transduction; Up-Regulation | 2019 |
High-throughput quantification of ten antiarrhythmic drugs in human plasma using UPLC-MS/MS.
Topics: Anti-Arrhythmia Agents; Atenolol; Bisoprolol; Carvedilol; Chromatography, High Pressure Liquid; Diltiazem; Flecainide; High-Throughput Screening Assays; Humans; Lidocaine; Metoprolol; Propranolol; Reproducibility of Results; Sotalol; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Verapamil | 2019 |
The adrenergic receptor antagonists propranolol and carvedilol decrease bone sarcoma cell viability and sustained carvedilol reduces clonogenic survival and increases radiosensitivity in canine osteosarcoma cells.
Topics: Adrenergic beta-Antagonists; Animals; Bone Neoplasms; Carvedilol; Cell Line, Tumor; Dog Diseases; Dogs; Humans; Osteosarcoma; Propranolol; Radiation Tolerance; Sarcoma, Ewing | 2020 |
KASL clinical practice guidelines for liver cirrhosis: Varices, hepatic encephalopathy, and related complications.
Topics: Adrenergic beta-Antagonists; Ammonia; Anti-Bacterial Agents; Carvedilol; Disaccharides; Endoscopy, Gastrointestinal; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Hepatic Encephalopathy; Humans; Hypertension, Portal; Liver Cirrhosis; Propranolol; Quality of Life; Vasoconstrictor Agents | 2020 |
β-Blocker Use and Risk of Mortality in Heart Failure Patients Initiating Maintenance Dialysis.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Atenolol; Bisoprolol; Carvedilol; Cause of Death; Cohort Studies; Female; Heart Failure; Hospitalization; Humans; Kidney Failure, Chronic; Labetalol; Logistic Models; Male; Metoprolol; Middle Aged; Mortality; Nadolol; Proportional Hazards Models; Propranolol; Protective Factors; Renal Dialysis; Retrospective Studies; Risk; Risk Factors | 2021 |
The effects of carvedilol, metoprolol and propranolol on cisplatin-induced kidney injury.
Topics: Adrenergic beta-Antagonists; Animals; Carvedilol; Cisplatin; Creatinine; Kidney; Metoprolol; Propranolol; Rats; Technetium Tc 99m Dimercaptosuccinic Acid | 2022 |
Carvedilol as secondary prophylaxis for variceal bleeding in hepatosplenic schistosomiasis.
Topics: Carvedilol; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Ligation; Propranolol; Retrospective Studies; Schistosomiasis | 2022 |
Carvedilol Achieves Higher Hemodynamic Response and Lower Rebleeding Rates Than Propranolol in Secondary Prophylaxis.
Topics: Adrenergic beta-Antagonists; Carvedilol; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Hemodynamics; Humans; Liver Cirrhosis; Propranolol; Retrospective Studies; Varicose Veins | 2023 |
Carvedilol ameliorates dexamethasone-induced myocardial injury in rats independent of its action on the α1-adrenergic receptor.
Topics: Adrenergic beta-Antagonists; Animals; Carbazoles; Cardiotoxicity; Carvedilol; Dexamethasone; Phenylephrine; Propanolamines; Propranolol; Rats | 2022 |
Noradrenergic consolidation of social recognition memory is mediated by β-arrestin-biased signaling in the mouse prefrontal cortex.
Topics: Animals; beta-Arrestins; Carvedilol; Mice; Norepinephrine; Prefrontal Cortex; Propranolol; Receptors, Adrenergic, beta; Signal Transduction | 2022 |
[Investigate of the etiology and prevention status of liver cirrhosis].
Topics: Carvedilol; Hepatitis B, Chronic; Hepatitis C, Chronic; Humans; Liver Cirrhosis; Liver Diseases, Alcoholic; Propranolol; Retrospective Studies | 2023 |