carvedilol has been researched along with prazosin in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (9.09) | 18.7374 |
| 1990's | 8 (24.24) | 18.2507 |
| 2000's | 11 (33.33) | 29.6817 |
| 2010's | 10 (30.30) | 24.3611 |
| 2020's | 1 (3.03) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Nagashima, R; Nishikawa, T; Tobita, M | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Ang, KK; Arkin, MR; Chen, S; Doyle, PS; Engel, JC; McKerrow, JH | 1 |
| Sen, S; Sinha, N | 1 |
| Giacomini, KM; Huang, Y; Khuri, N; Kido, Y; Kosaka, A; Morrissey, KM; Sali, A; Wittwer, MB; Zhang, X; Zur, AA | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Beermann, C; Belz, GG; Schloos, J | 1 |
| Gagnon, R; Slivjak, MJ; Smith, EF | 1 |
| Carugo, S; Cattaneo, BM; Giannattasio, C; Grassi, G; Mancia, G; Mangoni, AA; Seravalle, G; Zanchetti, A | 1 |
| Lund-Johansen, P; Omvik, P | 1 |
| Bartsch, W; Böhm, E; Hooper, RG; Sponer, G; Strein, K | 1 |
| Mikami, H; Ogihara, T | 1 |
| Akashi, A; Hashimoto, H; Kanda, A; Tanaka, M | 1 |
| Nagano, T; O'Harrow, S; Sponer, G; Zimmer, HG | 1 |
| Irlbeck, M; Zimmer, HG | 1 |
| Fyhrquist, F; Metsärinne, K; Saijonmaa, O | 1 |
| Heintz, B; Kirsten, D; Kirsten, R; Nelson, K | 1 |
| Aoyama, M; Fukutomi, T; Horio, T; Ito, S; Itoh, M; Nakata, K; Suzuki, S; Suzumura, H; Takeda, Y; Yamada, Y | 1 |
| Fredersdorf, S; Grimm, D; Huber, M; Jabusch, HC; Kromer, EP; Paul, M; Riegger, GA; Shakibaei, M | 1 |
| Bøkenes, J; Osnes, JB; Qvigstad, E; Sandnes, D; Schiander, I; Sjaastad, I; Skomedal, T | 1 |
| Harada, N; Isobe, H; Okajima, K; Uchiba, M | 1 |
| Bernaudin, JF; Buvry, A; Dhonneur, G; Favret, F; Fouillit, M; Germain, L; Guernier, C; Morel, OE; Richalet, JP; Tual, L | 1 |
| Onay-Besikci, A; Ozcelikay, AT; Suzmecelik, E | 1 |
| Ebe, R; Fukase, S; Horikoshi, Y; Inagawa, K; Osakabe, N; Saito, A; Shibata, M | 1 |
| Hamaguchi, S; Hasegawa, N; Ichige, S; Irie, M; Mochizuki, S; Namekata, I; Shimobayashi, M; Tanaka, H; Tanaka, Y; Tsuneoka, Y | 1 |
| DalirAkbari, N; Farshi, A; Khalili, M; Mahmoudinezhad, M; Zomorrodi, A | 1 |
2 review(s) available for carvedilol and prazosin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Clinical pharmacokinetics of vasodilators. Part II.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Alprostadil; Amrinone; Carbazoles; Carvedilol; Enoximone; Female; Humans; Iloprost; Imidazoles; Indoramin; Isosorbide Dinitrate; Labetalol; Milrinone; Molsidomine; Nitroglycerin; Nitroprusside; Oxyfedrine; Pentaerythritol Tetranitrate; Phosphodiesterase Inhibitors; Piperazines; Prazosin; Pregnancy; Propanolamines; Pyridones; Theophylline; Trapidil; Vasodilator Agents | 1998 |
3 trial(s) available for carvedilol and prazosin
| Article | Year |
|---|---|
Oral administration of carvedilol and prazosin inhibits the prostaglandin F2 alpha- and noradrenaline-induced contraction of human hand veins in vivo.
Topics: Administration, Oral; Adult; Animals; Antihypertensive Agents; Carbazoles; Carvedilol; Dinoprost; Dose-Response Relationship, Drug; Hand; Humans; Male; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Propanolamines; Radioligand Assay; Rats; Receptors, Adrenergic, alpha; Single-Blind Method; Vasoconstriction; Vasodilator Agents | 1992 |
Alpha 1-blocking properties of carvedilol during acute and chronic administration.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Blood Pressure; Carbazoles; Carvedilol; Double-Blind Method; Drug Interactions; Female; Heart Rate; Humans; Injections, Intravenous; Isoproterenol; Male; Middle Aged; Phenylephrine; Prazosin; Propanolamines; Random Allocation; Vasodilator Agents | 1992 |
A Randomized Crossover Pilot Study Examining the Effect of Carvedilol and Terazosin plus Enalapril on Urinary Symptoms of Patients with Hypertension and Benign Prostatic Hyperplasia.
Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Antihypertensive Agents; Carvedilol; Cross-Over Studies; Drug Therapy, Combination; Enalapril; Humans; Hypertension; Male; Middle Aged; Pilot Projects; Prazosin; Prostatic Hyperplasia; Single-Blind Method | 2021 |
28 other study(ies) available for carvedilol and prazosin
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Image-based high-throughput drug screening targeting the intracellular stage of Trypanosoma cruzi, the agent of Chagas' disease.
Topics: Animals; Cattle; Cell Line; Cell Line, Tumor; Chagas Disease; Drug Evaluation, Preclinical; Hepatocytes; High-Throughput Screening Assays; Humans; Image Processing, Computer-Assisted; Muscle, Skeletal; Parasitic Sensitivity Tests; Trypanocidal Agents; Trypanosoma cruzi | 2010 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling.
Topics: Computer Simulation; Fluorescent Dyes; Organic Cation Transport Proteins; Prescription Drugs | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Single and repeated doses of the vasodilator/beta-adrenergic antagonist, carvedilol, block cirazoline- and isoproterenol-mediated hemodynamic responses in the conscious rat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Carbazoles; Carvedilol; Hemodynamics; Imidazoles; Isoproterenol; Male; Prazosin; Propanolamines; Propranolol; Rats; Rats, Sprague-Dawley; Time Factors; Vasodilator Agents | 1992 |
The initial hemodynamic response to newer antihypertensive agents at rest and during exercise: review of visacor, doxazosin, nisoldipine, tiapamil, perindoprilat, pinacidil, dilevalol, and carvedilol.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzeneacetamides; Calcium Channel Blockers; Carbazoles; Carvedilol; Doxazosin; Female; Guanidines; Hemodynamics; Humans; Indoles; Labetalol; Male; Middle Aged; Nisoldipine; Pinacidil; Potassium Channels; Prazosin; Propanolamines; Propylamines; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Tiapamil Hydrochloride | 1990 |
Evaluation of the risk for drug-induced postural hypotension in an experimental model: investigations with carvedilol, prazosin, labetalol, and guanethidine.
Topics: Animals; Blood Pressure; Carbazoles; Carvedilol; Disease Models, Animal; Guanethidine; Hypotension, Orthostatic; Labetalol; Prazosin; Propanolamines; Rabbits; Risk; Vasodilator Agents | 1987 |
[Clinical application of adrenoceptor blockers in the treatment of hypertension].
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Humans; Hypertension; Labetalol; Prazosin; Propanolamines; Quinazolines | 1989 |
Analysis of the mechanism underlying the vasodilator action of carvedilol in pithed spontaneously hypertensive rats.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Carbazoles; Carvedilol; Decerebrate State; Dose-Response Relationship, Drug; Drug Interactions; Hydralazine; Hypertension; Labetalol; Prazosin; Propanolamines; Rats; Rats, Inbred SHR; Vasodilator Agents | 1988 |
Norepinephrine-induced changes in rat heart function, metabolism, and weight are antagonized by carvedilol.
Topics: Adrenergic beta-Antagonists; Animals; Body Weight; Carbazoles; Carvedilol; Female; Glucosephosphate Dehydrogenase; Heart; Heart Rate; Infusions, Intravenous; Myocardial Contraction; Myocardium; Norepinephrine; Prazosin; Propanolamines; Propranolol; Rats; Rats, Sprague-Dawley | 1993 |
Acute effects of catecholamines on function of the rat right heart.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Carbazoles; Carvedilol; Catecholamines; Female; Heart Rate; Isoproterenol; Metoprolol; Norepinephrine; Prazosin; Propanolamines; Rats; Rats, Sprague-Dawley; Ventricular Function, Right | 1993 |
Carvedilol and its metabolites suppress endothelin-1 production in human endothelial cell culture.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Ascorbic Acid; Calcium Channel Blockers; Carbazoles; Carvedilol; Cells, Cultured; Endothelin-1; Endothelium, Vascular; Humans; Metoprolol; Nicardipine; Prazosin; Probucol; Propanolamines; Propranolol; Umbilical Veins | 1997 |
Effect of carvedilol on atrioventricular conduction in the ischemic heart.
Topics: Action Potentials; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Bundle of His; Carbazoles; Carvedilol; Guinea Pigs; Male; Myocardial Ischemia; Papillary Muscles; Prazosin; Propanolamines; Propranolol; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2001 |
Extracellular matrix proteins in cardiac fibroblasts derived from rat hearts with chronic pressure overload: effects of beta-receptor blockade.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Blotting, Western; Carbazoles; Carvedilol; Cell Division; Cells, Cultured; Extracellular Matrix Proteins; Fibroblasts; Fluorescent Antibody Technique, Indirect; Heart Ventricles; Hemodynamics; Hypertrophy, Left Ventricular; Interferon-gamma; Male; Metoprolol; Myocardium; Prazosin; Propanolamines; Rats; Rats, Wistar; Ventricular Pressure | 2001 |
Carvedilol blockade of rat myocardial alpha1-adrenoceptors.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Binding, Competitive; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscle Contraction; Myocardial Contraction; Norepinephrine; Papillary Muscles; Phenylephrine; Prazosin; Propanolamines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta; Tritium | 2003 |
Activation of capsaicin-sensitive sensory neurons by carvedilol, a nonselective beta-blocker, in spontaneous hypertensive rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Bisoprolol; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Carbazoles; Carvedilol; Cells, Cultured; Drug Interactions; Female; Humans; Hypertension; Kidney; Male; Mice; Neurons, Afferent; Prazosin; Propanolamines; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Regional Blood Flow | 2004 |
Carvedilol inhibits right ventricular hypertrophy induced by chronic hypobaric hypoxia.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Carbazoles; Carvedilol; Chronic Disease; Hypertrophy, Right Ventricular; Hypoxia; Male; Prazosin; Pressure; Propanolamines; Rats; Rats, Wistar; Treatment Outcome | 2006 |
Carvedilol suppresses fatty acid oxidation and stimulates glycolysis in C2C12 cells.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Bisoprolol; Carbazoles; Carvedilol; Cell Line; Epinephrine; Fatty Acids; Glycolysis; Mice; Oxidation-Reduction; Palmitic Acid; Prazosin; Propanolamines; Propranolol; Sympathomimetics | 2012 |
Onset of a hypotensive effect following ingestion of flavan 3-ols involved in the activation of adrenergic receptors.
Topics: Adrenergic Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Butoxamine; Cacao; Carbazoles; Carvedilol; Catechin; Epinephrine; Flavonoids; Gene Expression Regulation; Heart Rate; Male; Nitric Oxide Synthase Type III; Phosphorylation; Prazosin; Propanolamines; Rats; Rats, Wistar; Receptors, Adrenergic; Yohimbine | 2016 |
Involvement of alpha- and beta-adrenoceptors in the automaticity of the isolated guinea pig pulmonary vein myocardium.
Topics: Animals; Atenolol; Atrial Fibrillation; Carbazoles; Carvedilol; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Myocardium; Norepinephrine; Prazosin; Propanolamines; Pulmonary Veins; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Vasoconstriction | 2017 |