carvedilol and nifedipine

carvedilol has been researched along with nifedipine in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.23)18.7374
1990's9 (29.03)18.2507
2000's14 (45.16)29.6817
2010's7 (22.58)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Keserü, GM1
Du, LP; Li, MY; Tsai, KC; Xia, L; You, QD1
Nagashima, R; Nishikawa, T; Tobita, M1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Jia, L; Sun, H1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Sen, S; Sinha, N1
Bakmiwewa, SM; Ball, HJ; Fatokun, AA; Hunt, NH; Payne, RJ; Tran, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bennis, K; Ducki, S; Lesage, F; Vivier, D1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Derr, I; Eberhardt, R; Ehmer, B; van der Does, R1
de Vries Robles, P; Juttmann, JR; Venuti, RP1
Adezati, L; Albergati, F; Boeri, D; Lombardo, I; Paternó, E; Semino, S; Venuti, RP; Viviani, GL1
Ball, SG; Dixon, S; Hall, S; Hallman, RJ; Harvey, RE; Prescott, RI1
Derr, I; Eberhardt, R; Ehmer, B; Rudorf, J; Uberbacher, HJ; van der Does, R1
Hoffmeister, HM; Ickrath, O; Karsch, KR; Mauser, M; Voelker, W1
Dantas, M; Freitas, AF; Furtado, MR; Kohlmann, NE; Kohlmann, O; Plavnik, FL; Portela, JE; Spritzer, N; Spritzer, T1
Arleth, AJ; Ohlstein, EH; Sung, CP1
Sullivan, JM1
Feuerstein, GZ; Fisher, M; Nunnart, J; Ruffolo, RR1
Hobara, N; Hokama, N; Kameya, H; Ohshiro, S; Sakai, M; Sakanashi, M1
Antonello, A; Calò, L; Davis, PA; Giacon, B; Huber, W; Pagnin, E; Piccin, A; Riegler, P; Semplicini, A1
Iida, H; Iwasawa, K; Jo, T; Ma, J; Nagai, R; Nakajima, T; Omata, M1
Angeli, P; Boccagni, P; Burra, P; Carraro, A; Cillo, U; Fagiuoli, S; Fasolato, S; Galioto, A; Gatta, A; Guarda, S; Sartori, M; Semplicini, A; Sticca, A; Zanus, G1
Angeli, P; Boccagni, P; Cillo, U; Fasolato, S; Frigo, AC; Galioto, A; Gatta, A; Semplicini, A; Sticca, A; Zanus, G1

Reviews

3 review(s) available for carvedilol and nifedipine

ArticleYear
Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target?
    Journal of medicinal chemistry, 2016, 06-09, Volume: 59, Issue:11

    Topics: Arrhythmias, Cardiac; Depression; Epilepsy; Humans; Inflammation; Models, Molecular; Molecular Structure; Neuroprotective Agents; Pain; Potassium Channels, Tandem Pore Domain; Structure-Activity Relationship

2016
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
A 1996 update on antihypertensive agents.
    Current opinion in cardiology, 1996, Volume: 11, Issue:5

    Topics: Angiotensin Receptor Antagonists; Antihypertensive Agents; Calcium Channel Blockers; Carbazoles; Carvedilol; Diuretics; Endothelins; Humans; Hypertension; Neprilysin; Nifedipine; Propanolamines

1996

Trials

10 trial(s) available for carvedilol and nifedipine

ArticleYear
Efficacy and safety of carvedilol in comparison with nifedipine sustained-release in chronic stable angina.
    Journal of cardiovascular pharmacology, 1992, Volume: 19 Suppl 1

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Antihypertensive Agents; Carbazoles; Carvedilol; Delayed-Action Preparations; Double-Blind Method; Exercise Test; Humans; Male; Middle Aged; Nifedipine; Nitroglycerin; Propanolamines; Vasodilator Agents

1992
Safety of the coadministration of carvedilol and nifedipine sustained-release in the treatment of essential hypertension.
    Journal of cardiovascular pharmacology, 1992, Volume: 19 Suppl 1

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Carbazoles; Carvedilol; Delayed-Action Preparations; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Propanolamines

1992
Comparison of the effects of carvedilol and nifedipine in patients with essential hypertension and non-insulin-dependent diabetes mellitus.
    Journal of cardiovascular pharmacology, 1992, Volume: 19 Suppl 1

    Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Blood Pressure; Carbazoles; Carvedilol; Diabetes Mellitus, Type 2; Female; Glucose Tolerance Test; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Propanolamines; Vasodilator Agents

1992
A comparative study of carvedilol, slow-release nifedipine, and atenolol in the management of essential hypertension.
    Journal of cardiovascular pharmacology, 1991, Volume: 18 Suppl 4

    Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Carbazoles; Carvedilol; Delayed-Action Preparations; Electrocardiography; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Propanolamines; Vasodilator Agents

1991
Treatment of chronic stable angina with carvedilol in comparison with nifedipine s.r.
    European heart journal, 1991, Volume: 12, Issue:1

    Topics: Adult; Aged; Angina Pectoris; Carbazoles; Carvedilol; Chronic Disease; Delayed-Action Preparations; Double-Blind Method; Exercise Test; Female; Humans; Male; Middle Aged; Nifedipine; Propanolamines; Vasodilator Agents

1991
[The acute hemodynamic effects of the new vasodilating beta blocker carvedilol in comparison with combined administration of nifedipine and propranolol in patients with coronary heart disease].
    Zeitschrift fur Kardiologie, 1989, Volume: 78, Issue:11

    Topics: Carbazoles; Carvedilol; Coronary Circulation; Coronary Disease; Drug Therapy, Combination; Female; Hemodynamics; Humans; Infusions, Intravenous; Male; Middle Aged; Myocardial Infarction; Nifedipine; Propanolamines; Propranolol; Vasodilator Agents

1989
[Use of carvedilol compared to nifedipine in the treatment of mild and moderate essential arterial hypertension].
    Arquivos brasileiros de cardiologia, 1994, Volume: 63, Issue:5

    Topics: Aged; Analysis of Variance; Antihypertensive Agents; Carbazoles; Carvedilol; Clinical Protocols; Delayed-Action Preparations; Double-Blind Method; Heart Rate; Humans; Hypertension; Middle Aged; Nifedipine; Propanolamines

1994
Oxidative stress and TGFbeta in kidney-transplanted patients with cyclosporin-induced hypertension. Effect of carvedilol and nifedipine.
    Clinical nephrology, 2002, Volume: 58, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Carbazoles; Carvedilol; Cyclosporine; Drug Evaluation; Female; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Hypertension; Immunosuppressive Agents; Kidney Transplantation; Male; Membrane Proteins; Middle Aged; Nifedipine; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxidative Stress; Postoperative Complications; Propanolamines; RNA, Messenger; Signal Transduction; Transforming Growth Factor beta; Treatment Outcome; Tyrosine

2002
Comparison between nifedipine and carvedilol in the treatment of de novo arterial hypertension after liver transplantation: preliminary results of a controlled clinical trial.
    Transplantation proceedings, 2005, Volume: 37, Issue:2

    Topics: Blood Pressure; Carbazoles; Carvedilol; Female; Heart Rate; Humans; Hypertension; Liver Transplantation; Male; Middle Aged; Nifedipine; Propanolamines; Treatment Outcome; Vasodilator Agents

2005
Nifedipine versus carvedilol in the treatment of de novo arterial hypertension after liver transplantation: results of a controlled clinical trial.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2008, Volume: 14, Issue:7

    Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Carbazoles; Carvedilol; Drug Therapy, Combination; Female; Humans; Hypertension; Immunosuppression Therapy; Kidney Function Tests; Liver Transplantation; Male; Middle Aged; Nifedipine; Propanolamines; Prospective Studies; Time Factors; Treatment Outcome

2008

Other Studies

18 other study(ies) available for carvedilol and nifedipine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2003
The pharmacophore hypotheses of I(Kr) potassium channel blockers: novel class III antiarrhythmic agents.
    Bioorganic & medicinal chemistry letters, 2004, Sep-20, Volume: 14, Issue:18

    Topics: Anti-Arrhythmia Agents; Models, Biological; Models, Molecular; Potassium Channel Blockers; Potassium Channels; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2004
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Support vector machines classification of hERG liabilities based on atom types.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve

2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Identification of selective inhibitors of indoleamine 2,3-dioxygenase 2.
    Bioorganic & medicinal chemistry letters, 2012, Dec-15, Volume: 22, Issue:24

    Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; HEK293 Cells; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Substrate Specificity

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Carvedilol inhibits vascular smooth muscle cell proliferation.
    Journal of cardiovascular pharmacology, 1993, Volume: 21, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Aorta, Thoracic; Carbazoles; Carvedilol; Cell Division; DNA; Endothelins; In Vitro Techniques; Male; Mitogens; Muscle, Smooth, Vascular; Nifedipine; Propanolamines; Prostaglandins F; Rats; Rats, Sprague-Dawley; Thymidine

1993
Carvedilol inhibits aortic lipid deposition in the hypercholesterolemic rat.
    Pharmacology, 1997, Volume: 54, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Aorta, Thoracic; Arteriosclerosis; Calcium Channel Blockers; Carbazoles; Carvedilol; Hypercholesterolemia; Lipid Metabolism; Male; Nifedipine; Propanolamines; Rats; Rats, Wistar; Vasodilator Agents

1997
Influence of nicardipine and nifedipine on plasma carvedilol disposition after oral administration in rats.
    The Journal of pharmacy and pharmacology, 2002, Volume: 54, Issue:6

    Topics: Administration, Oral; Animals; Area Under Curve; Calcium Channel Blockers; Carbazoles; Carvedilol; Chromatography, High Pressure Liquid; Drug Interactions; Male; Nicardipine; Nifedipine; Propanolamines; Rats; Rats, Sprague-Dawley; Time Factors

2002
Inhibitory effects of carvedilol on calcium channels in vascular smooth muscle cells.
    Japanese heart journal, 2003, Volume: 44, Issue:6

    Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Aorta; Calcium; Calcium Channels; Calcium Signaling; Carbazoles; Carvedilol; Cell Division; Endothelin-1; Metoprolol; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Propanolamines; Rats; Vasodilator Agents; Vasopressins

2003