carvedilol has been researched along with metoprolol in 448 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (0.89) | 18.7374 |
| 1990's | 36 (8.04) | 18.2507 |
| 2000's | 274 (61.16) | 29.6817 |
| 2010's | 108 (24.11) | 24.3611 |
| 2020's | 26 (5.80) | 2.80 |
| Authors | Studies |
|---|---|
| Carrupt, PA; Gaillard, P; Schambel, P; Testa, B | 1 |
| Amend, A; Candelore, MR; Cascieri, MA; Deng, L; Guan, XM; Liu, Y; Newbold, R; Tota, L; Weber, AE | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Funakoshi, J; Kakumoto, M; Okumura, K; Sakaeda, T; Takara, K; Tanigawara, Y | 1 |
| Baker, JG | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Carrupt, PA; Guillarme, D; Henchoz, Y; Rudaz, S; Veuthey, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
| Bard, B; Carrupt, PA; Martel, S | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Back, TG; Chen, SR; Smith, CD; Vembaiyan, K; Wang, A; Wu, G; Xie, C; Zhang, J; Zhou, Q | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Chang, Q; Chen, Z; Hu, G; Hu, L; Li, Q; Long, J | 1 |
| Agrawal, B; Franz, IW; Ketelhut, R; Wiewel, D | 1 |
| Bristow, MR; Handwerger, D; Klein, J; Larrabee, P; Minobe, W; Müller-Beckmann, B; Port, JD; Roden, R; Skerl, L | 1 |
| Kolbeck-Rühmkorff, C; Lankat-Buttgereit, B; Nagano, T; Zierhut, W; Zimmer, HG | 1 |
| Adam, W; Anderson, A; Cripps, J; Morgan, TO | 1 |
| Distler, A; Gotzen, R; Meyer-Sabellek, W; Schulte, KL | 2 |
| Butcher, L; Morgan, T; Snowden, R | 1 |
| Behr, M; Franz, IW; Ketelhut, R; Wiewel, D | 1 |
| Degaute, JP; Leeman, M; Uytdenhoef, M; Vereerstraeten, P | 1 |
| Belz, GG; Breithaupt-Grögler, K; De Mey, C; Palm, D; Schloos, J | 1 |
| Irlbeck, M; Zimmer, HG | 1 |
| Thon, H | 1 |
| Slinning, H | 1 |
| Agrawal, B; Augustin, HJ; Dietze, GJ; Jacob, S; Rett, K; Wicklmayr, M | 1 |
| Bohmeke, T; Taylor, SH; van der Does, R; Weber, K | 2 |
| Abraham, WT; Bristow, MR; Gilbert, EM; Hattler, B; Larrabee, P; Mealy, P; Olsen, S; White, M | 1 |
| Fyhrquist, F; Metsärinne, K; Saijonmaa, O | 1 |
| Doughty, RN; MacMahon, S; Rodgers, A; Sharpe, N | 1 |
| Abraham, WT; Bristow, MR; Crisman, TS; Gilbert, EM; Hattler, BG; Larrabee, P; Lowes, BD; Robertson, AD; White, M; Yoshikawa, T | 1 |
| Fowler, MB | 1 |
| Boccanelli, A; Camerini, F; Gavazzi, A; Gronda, E; Maggioni, AP; Opasich, C; Rapezzi, C; Scherillo, M; Sinagra, G; Tavazzi, L | 1 |
| Arch, JR; Cheng, HY; Feuerstein, G; Hieble, JP; Liu, GL; Ma, XL; Ruffolo, RR; Yue, TL | 1 |
| Bril, A; Khandoudi, N; Percevault-Albadine, J | 1 |
| Kakihana, M; Ohtsuka, S; Sugishita, Y; Watanabe, H | 1 |
| Griffiths, M; Hauf-Zachariou, U; Holtbrügge, W; König, S; Lahiri, A; Pfarr, E; van der Does, R | 1 |
| Buchholz-Varley, C; Charney, RH; Eng, C; Kalman, J; Kukin, ML; Levy, DK; Ocampo, ON | 1 |
| Camerini, F; Ciani, F; Di Lenarda, A; Gregori, D; Klugmann, S; Mestroni, L; Muzzi, A; Pinamonti, B; Sabbadini, G; Salvatore, L; Sinagra, G | 1 |
| Carson, PE | 1 |
| Bäumer, AT; Böhm, M; Cremers, B; Flesch, M; Maack, C; Südkamp, M | 1 |
| Eichhorn, EJ; Fesmire, SI; Kennedy, HL; Lyyski, DS; Marcoux, LG; Sprague, MK | 1 |
| Sasse, A; Schotten, U; vom Dahl, J | 1 |
| Chan, KW; Chan, SK; Raymond, K; Sanderson, JE; Woo, KS; Yeung, LY; Yip, G | 1 |
| Beller, KD; Diedrich, F; Sponer, G | 1 |
| McMurray, JJ | 1 |
| Witkowska, M | 1 |
| Song, J; White, CM | 1 |
| Bristow, MR | 2 |
| Daniel, WG; Garlichs, C | 1 |
| Intengan, HD; Schiffrin, EL | 1 |
| Dunn, AB; Reddy, P | 1 |
| Böhm, M; Cremers, B; Flesch, M; Höper, A; Maack, C; Südkamp, M | 1 |
| Chow, LT; Sanderson, JE; Wei, S | 1 |
| Bristow, MR; Ferguson, D; Lindenfeld, J; Lowes, BD; Noori, A; Wolfel, E | 1 |
| Goldstein, S; Gottlieb, SS | 1 |
| Boldi, E; Dei Cas, L; Giubbini, R; Metra, M; Modena, MG; Nodari, S | 1 |
| Carek, PJ; Dickerson, LM | 1 |
| Cleland, JG | 2 |
| Gu, JL; Lysko, PG; Ohlstein, EH; Ruffolo, RR; Webb, CL; Yue, TL | 1 |
| Denbow, CE | 1 |
| Hjalmarson, A | 1 |
| Kukin, ML | 1 |
| Gilbert, EM; Port, JD | 1 |
| Boldi, E; Dei Cas, L; Metra, M; Nodari, S | 1 |
| Frantz, RP | 1 |
| Krum, H; Whorlow, SL | 1 |
| Spinar, J; Vítovec, J | 1 |
| Movahed, A | 1 |
| Chavey, WE | 1 |
| Hart, SM | 1 |
| Arumanayagam, M; Chan, S; Sanderson, JE; Tong, S | 1 |
| Böhm, M; Cremers, B; Ettelbrück, S; Flesch, M; Maack, C; Rosenkranz, S; Schlüter, KD; Zolk, O | 1 |
| Fredersdorf, S; Grimm, D; Huber, M; Jabusch, HC; Kromer, EP; Paul, M; Riegger, GA; Shakibaei, M | 1 |
| Arrocha, A; Calzada, N; Motta, J; Nuñez, P; Pichel, D; Rodríguez, A | 1 |
| Gregory, D; Konstam, MA; Udelson, JE | 1 |
| Antonopoulos, GV; Berlin, JA; Chittams, J; Konstam, MA; Packer, M; Udelson, JE | 1 |
| Fruhwald, FM; Klein, W; Koshucharova, G; Maier, R; Stoschitzky, K; Watzinger, N; Zweiker, R | 1 |
| Lee, S; Spencer, A | 1 |
| De Boer, RA; Van Veldhuisen, DJ | 1 |
| Coutinho, J | 1 |
| Bloch, W; Bölck, B; Brixius, K; Bundkirchen, A; Mehlhorn, U; Schwinger, RH | 1 |
| Bölck, B; Brixius, K; Bundkirchen, A; Mehlhorn, U; Schwinger, RH | 1 |
| Briggs, AH; Demers, C; Levy, AR; O'Brien, BJ | 1 |
| Czuriga, I; Edes, I | 1 |
| Böhm, M; Crivaro, M; Elter, T; LaRosee, K; Maack, C; Nickenig, G; Stäblein, A; Wuttke, H | 1 |
| Al-Hesayen, A; Allan, R; Azevedo, ER; Floras, JS; Kelly, S; Kubo, T; Mak, S; Newton, GE; Parker, JD; Schofield, A | 1 |
| Azevedo, ER; Floras, JS; Kubo, T; Newton, GE; Parker, JD | 1 |
| Hanatani, A; Hirooka, K; Hori, M; Ishida, Y; Komamura, K; Miyatake, K; Nakatani, S; Yamagishi, M; Yasumura, Y | 1 |
| Ghanem, WM; Murin, J; Sleiman, OI | 1 |
| Stoschitzky, K | 1 |
| Maehara, K; Maruyama, Y; Sakabe, A; Yaoita, H | 1 |
| Antell, LA; Chang, LL; Luzier, AB; Roth, DA; Xuan, J | 1 |
| Hamada, M; Hara, Y; Hiasa, Go; Hiwada, K; Ogimoto, A; Ohtsuka, T; Saeki, H; Shigematsu, Y | 1 |
| Adler, S; Kraatz, E; Kurz, T; Nötzold, A; Richardt, D; Richardt, G | 1 |
| Abraham, WT; Bristow, MR; Ferguson, D; Gilbert, EM; Larrabee, P; Lindenfeld, J; Lowes, BD; Minobe, WA; Quaife, RA; Robertson, AD; Tsvetkova, T; Wolfel, EE | 1 |
| Hauptman, PJ; Prirzker, MR; Woods, D | 1 |
| Cleland, JG; Di Lenarda, A; Hanrath, P; J Remme, W; Komajda, M; Metra, M; Poole-Wilson, PA; Swedberg, K; Torp-Pedersen, C | 1 |
| Shaddy, RE; Tani, LY; Williams, RV | 1 |
| Bobadilla, RV | 1 |
| Chan, SK; Fung, JW; Sanderson, JE; Yeung, LY | 1 |
| Cherubini, A; Di Lenarda, A; Perkan, A; Salvatore, L; Sinagra, G | 1 |
| Anguita Sánchez, M | 1 |
| Bristow, MR; D'Aloia, A; Dei Cas, L; Metra, M; Muneretto, C; Nodari, S; Robertson, AD | 1 |
| Di Carlo, S; Lionetti, M; Marigliano, V; Moisè, A; Naso, C; Nocco, M; Piccirillo, G; Quaglione, R | 1 |
| Bruns, LA; Canter, CE | 1 |
| Hamada, M; Hara, Y; Matsunaka, T; Nakata, S; Ogimoto, A; Ohtsuka, T; Saeki, H; Shigematsu, Y; Suzuki, J | 1 |
| Abraham, WT; Bristow, MR; Dutcher, D; Ferguson, D; Gilbert, EM; Larrabee, P; Lindenfeld, JA; Linseman, JV; Lowes, BD; Minobe, WA; Quaife, RA; Robertson, AD; Roden, RL; Sederberg, J; Shakar, SF; Volkman, K; Wolfel, EE | 1 |
| Adams, KF; Felker, GM; Gattis, WA; Gheorghiade, M; Leimberger, JD; O'Connor, CM | 1 |
| Matsumori, A; Nishio, R; Sasayama, S; Shioi, T | 1 |
| Jorde, UP; Katz, SD; Lang, CC; Mancini, DM; Packer, M; Vittorio, TJ | 1 |
| Balli, E; Geraci, E; Gorini, M; Gronda, E; Lucci, D; Maggioni, AP; Opasich, C; Sinagra, G; Tavazzi, L; Tognoni, G | 1 |
| Dei Cas, L; Giubbini, R; Manca, C; Metra, M; Nodari, S; Parrinello, G | 1 |
| Andersson, B; Bollano, E; Hjalmarson, A; Täng, MS; Waagstein, F | 1 |
| Inoko, M; Nohara, R | 1 |
| Bouzamondo, A; Hulot, JS; Lechat, P; Sanchez, P | 1 |
| Etheridge, SP; Shaddy, RE | 1 |
| Goldstein, S; Sallach, JA | 1 |
| Dargie, HJ | 1 |
| Cleland, JG; Di Lenarda, A; Hanrath, P; Komajda, M; Lubsen, J; Lutiger, B; Metra, M; Poole-Wilson, PA; Remme, WJ; Scherhag, A; Skene, A; Swedberg, K; Torp-Pedersen, C | 1 |
| Davenport, JD; Gnanasekeram, H; Gopalan, R; Gracely, EJ; Narula, J; Rajput, FS; Satwani, S | 1 |
| Jiang, WP; Liu, ZH; Shen, B; Song, JP | 1 |
| Hamada, M; Hara, Y; Higaki, J; Ogimoto, A; Ohtsuka, T; Shigematsu, Y | 1 |
| Chen, JL; Chen, ZJ; Gao, RL; Lu, SQ; Ruan, YM; Sun, RC; Tang, YD; Wang, PH; Yang, YJ; Zhang, P | 1 |
| Androne, AS; Hryniewicz, K; Hudaihed, A; Katz, SD | 2 |
| Chan, S; Fung, JW; Nicholls, MG; Richards, AM; Sanderson, JE; Yandle, TG; Yip, G; Yu, CM | 1 |
| Clark, AL; Cleland, JG; Coletta, AP; Seymour, AM | 1 |
| Blanchet, M; Ducharme, A; Fortier, A; Juneau, M; Larivée, L; Marquis, J; Nigam, A; Racine, N; Rouleau, JL; Tardif, JC; White, M | 1 |
| Hammer, D; Merritt, JC; Mills, RM; Niebauer, M; Tarakji, K | 1 |
| Blanchet, M; Boucher, JM; Ducharme, A; Juneau, M; Marquis, J; Racine, N; White, M | 1 |
| Buller, GK; Coca, SG | 1 |
| Hjalmarson, A; Waagstein, F | 1 |
| Heinzl, S | 1 |
| Adachi, H; Hoshizaki, H; Isobe, N; Naito, S; Oshima, S; Seki, R; Taniguchi, K; Toyama, T | 1 |
| Swedberg, K | 1 |
| Andreev, DA; Aref'eva, AB; Konova, IA; Kukes, VG; Poltavskaia, MG; Rykova, MS; Syrkin, AL; Teplonogova, EV | 1 |
| Al-Nasser, F; Bolger, AP | 1 |
| Liebson, PR | 1 |
| Aberg, J; Johnsson, G | 1 |
| Goldstein, S | 1 |
| Hanrath, P | 1 |
| Schneider, CA | 1 |
| Ahmed, A | 1 |
| Doggrell, SA | 1 |
| Kihara, Y; Kishimoto, C; Onozawa, Y; Shioji, K; Takenaka, H; Yuan, Z | 1 |
| Francis, GS; Militello, M; Tang, WH | 1 |
| Gupta, R; Tang, WH; Young, JB | 1 |
| van Gilst, WH; van Veldhuisen, DJ; Voors, AA | 1 |
| Iida, H; Iwasawa, K; Jo, T; Ma, J; Nagai, R; Nakajima, T; Omata, M | 1 |
| Chen, J; Chen, Z; Gao, R; Ruan, Y; Tang, Y; Wang, Y; Yang, Y | 1 |
| Paul, S; Trupp, RJ | 1 |
| Gattis, W; Patel, MR | 1 |
| Massie, BM | 1 |
| Packer, M | 1 |
| Adams, KF; Bristow, MR; Feldman, AM; Goldstein, S | 1 |
| Shepherd, AM | 1 |
| Cohn, JN | 1 |
| Inoue, A; Yamashina, S; Yamazaki, J | 1 |
| von Haehling, S | 1 |
| Böger, RH; Fahlbusch, SA; Frölich, JC; Gutzki, FM; Mehls, C; Stichtenoth, DO; Tsikas, D | 1 |
| Ertl, G; Nitschmann, S | 1 |
| Eschenhagen, T; Rau, T; Wuttke, H | 1 |
| Durand, JB; Giesler, G; Lenihan, DJ | 1 |
| Kishimoto, C; Nimata, M; Shioji, K; Yuan, Z | 1 |
| Noutsias, M; Pauschinger, M; Rutschow, S; Schultheiss, HP; Schwimmbeck, PL; Steendijk, P; Tschöpe, C; Weitz, A; Westermann, D | 1 |
| Poole-Wilson, PA | 1 |
| Udelson, JE | 1 |
| Bell, DS | 1 |
| Charlesworth, A; Cleland, JG; Di Lenarda, A; Erhardt, L; Goode, K; Hanrath, P; Komajda, M; Metra, M; Poole-Wilson, PA; Remme, WJ; Swedberg, K; Torp-Pedersen, C | 1 |
| Böhm, M; Finkler, N; Kindermann, M; Läer, S; Maack, C; Schäfers, HJ; Schaller, S; Schmidt, KI; Wuttke, H | 1 |
| Abdulla, J; Køber, L; Torp-Pedersen, C | 1 |
| Coffey, CS; Curtis, JP; Foody, JM; Hebert, PR; Ko, DT; Krumholz, HM; Sedrakyan, A | 1 |
| Smith, KM | 1 |
| Di Lenarda, A; Sabbadini, G; Sinagra, G | 1 |
| Bauman, JL; Talbert, RL | 1 |
| Baba, A; Iwanaga, S; Mitamura, H; Moritani, K; Nakamura, I; Ogawa, S; Satoh, T; Suzuki, M; Yoshikawa, T; Yoshizawa, A | 1 |
| Ahmed, A; Dell'Italia, LJ | 1 |
| Torp-Pedersen, CT | 1 |
| Kaufmann, PA; Klainguti, M; Koepfli, P; Lüscher, TF; Namdar, M; von Schulthess, GK; Wyss, CA | 1 |
| Bozhko, AA; Kanopskiĭ, SG; Staritskiĭ, AG | 1 |
| Jafri, SM | 1 |
| Talbert, RL | 1 |
| Anh, D; Marine, JE | 1 |
| Nordling, MK | 1 |
| Anderson, KM; Bakris, GL; Bell, DS; Fonseca, V; Katholi, RE; Lukas, MA; McGill, JB; Messerli, FH; Oakes, R; Phillips, RA; Raskin, P; Wright, JT | 1 |
| McBride, BF; White, CM | 1 |
| Sica, DA | 1 |
| Bode, F; Bonnemeier, H; Ortak, J; Richardt, G; Schmidt, J; Schunkert, H; Tölg, R; Wiegand, UK; Witt, M | 2 |
| Delea, TE; Edelsberg, JS; Hagiwara, M; Oster, G; Stanford, R | 1 |
| Rone, T; Sauls, JL | 1 |
| Gonzalez-Feldman, E | 1 |
| Charlesworth, A; Cleland, J; Hanrath, P; Komajda, M; Metra, M; Olsson, LG; Poole-Wilson, P; Swedberg, K; Torp-Pedersen, C | 1 |
| Murakami, T | 1 |
| Cacciapuoti, F; D'Amico, M; Di Filippo, C; Esposito, K; Giugliano, D; Gualdiero, P; Marfella, R; Nappo, F; Rossi, F; Sasso, FC; Siniscalchi, M | 1 |
| Cinquegrana, G; D'Aniello, L; De Prisco, F; Grande, G; Landi, M; Petretta, M; Spinelli, L | 1 |
| Anshelevich, M; Burcham, JL; Green, P; Le Jemtel, TH; Ravi, SM; Shirani, J; Talreja, A | 1 |
| Cleland, JG; Di Lenarda, A; Hanrath, P; Komajda, M; Lutiger, B; Metra, M; Poole-Wilson, PA; Remme, WJ; Scherhag, A; Skene, A; Swedberg, K; Torp-Pedersen, C | 1 |
| Díez Manglano, J | 1 |
| Charlesworth, A; Cleland, JG; Ekman, I; Metra, M; Poole-Wilson, PA; Swedberg, K | 1 |
| Chandrasekharan, K; Li, J; Noutsias, M; Pauschinger, M; Peter Schwimmbeck, L; Poller, W; Rutschow, S; Schultheiss, HP; Tschope, C; Weitz, A; Westermann, D; Zeichhardt, H | 1 |
| Al-Hesayen, A; Azevedo, ER; Floras, JS; Hollingshead, S; Lopaschuk, GD; Parker, JD | 1 |
| Charlesworth, A; Cleland, JG; Di Lenarda, A; Komajda, M; Lutiger, B; Metra, M; Poole-Wilson, PA; Remme, WJ; Scherhag, A; Swedberg, K; Torp-Pedersen, C | 1 |
| Hara, Y; Higaki, J; Inoue, K; Nakata, S; Ogimoto, A; Ohtsuka, T; Shigematsu, Y | 1 |
| Allison, TG; Gau, GT; Johnson, BD; Olson, LJ; Somers, VK; Squires, RW; Wolk, R | 1 |
| Reiffel, JA | 1 |
| Kowey, PR | 1 |
| Adams, KF | 2 |
| Baruch, L; Kunamneni, P | 1 |
| Charlesworth, A; Cleland, JG; Di Lenarda, A; Komajda, M; Lukas, MA; Lutiger, B; Metra, M; Poole-Wilson, PA; Remme, WJ; Scherhag, A; Swedberg, K; Torp-Pedersen, C | 1 |
| Chan, SK; Fung, JW; Leung, LY; Sanderson, JE; Yip, GW; Yu, CM | 1 |
| Cohen-Solal, A; Dietz, R; Eichhorn, E; Erhardt, L; Hobbs, FD; Krum, H; Maggioni, A; McKelvie, RS; McMurray, J; Piña, IL; Soler-Soler, J; Swedberg, K | 1 |
| Atchison, DJ; Azevedo, ER; Floras, JS; Kubo, T; Newton, GE; Parker, JD; Picton, P | 1 |
| Andrews, M; Brodine, WN; Daubert, JP; Hall, WJ; Hockstad, ES; Lee, JK; McNitt, S; Moss, AJ; Tung, RT; Zareba, W | 1 |
| Andersson, G; Boman, K; Charlesworth, A; Cleland, JG; Ekman, I; Poole-Wilson, P; Swedberg, K | 1 |
| Hu, SJ; Hu, Y; Sun, YL; Wang, LH; Zhou, JY | 1 |
| Diep, TP; Grohmann, B; Gupta, R; Kostin, S; Nowak, B; Schaper, J; Schwarz, ER; Uretsky, BF | 1 |
| Christ, T; Kaumann, A; Molenaar, P; Ravens, U | 1 |
| Williams, RE | 1 |
| Anderson, KM; Bakris, GL; Bell, DS; Fonseca, V; Katholi, RE; Lukas, MA; McGill, JB; Messerli, F; Phillips, RA; Raskin, P; Waterhouse, B; Wright, JT | 1 |
| Abe, H; Anson, BD; Delisle, BP; January, CT; Kawakami, K; Kikuchi, K; Nagatomo, T; Nakashima, Y; Takemasa, H | 1 |
| Makarova, SV; Praskurnichiĭ, EA; Shevchenko, OP; Zhukova, VA | 1 |
| Bader, FM; Crompton, JA; Gilbert, EM; Hagan, ME | 1 |
| Anzai, T; Kohno, T; Nakamura, I; Ogawa, S; Satoh, T; Yoshikawa, T; Yoshizawa, A | 1 |
| Fukagawa, Y; Harada, N; Kametani, R; Kawamura, S; Matsuzaki, M; Miura, T; Shibuya, M; Tan, H; Wang, R | 1 |
| Altimir, S; Coll, R; Díez, C; González, B; Herreros, J; Lupón, J; Rey-Joly, C; Urrutia, A; Valle, V | 1 |
| Geist, V; Hartmann, F; Kurowski, V; Kurz, T; Richardt, G; Schwarz, B; Tölg, R; Witt, M | 1 |
| Altuntas, Y; Basat, O; Oztekin, E; Seber, S; Ucak, S | 1 |
| Filipiak, KJ; Opolski, G | 1 |
| Cleland, JG; Dei Cas, L; Metra, M | 1 |
| Charlesworth, A; Cleland, JG; Di Lenarda, A; Erhardt, L; Komajda, M; Lubsen, J; Metra, M; Poole-Wilson, PA; Remme, WJ; Swedberg, K; Torp-Pedersen, C | 1 |
| Lewis, E; Stevenson, LW | 1 |
| Magovern, M; Nikolaidis, LA; Parikh, P; Poornima, I; Shannon, RP; Shen, YT | 1 |
| Batenburg, WW; Danser, AH; Dekkers, DH; Garrelds, IM; Jorde, U; Kellett, E; Lamers, JM; Milligan, G; van Esch, JH; van Kats, JP; Walther, T | 1 |
| Hayashi, Y; Kamei, M; Kanmura, Y; Kuro, M; Morita, S | 1 |
| Champagne, J; Connolly, SJ; Dorian, P; Fain, E; Gent, M; Hohnloser, SH; Israel, CW; Roberts, R | 1 |
| Berlowitz, DR; Cunningham, F; Gomez-Caminero, A; Miller, DR; Oliveria, SA; Rothendler, JA | 1 |
| Machavariani, PT; Nakashidze, NM | 1 |
| Christiansen, B; Kveiborg, B; Major-Petersen, A; Torp-Pedersen, C | 2 |
| Cai, Y; Jia, J; Li, S; Liu, G; Liu, Y; Pan, C; Ren, J; Yu, C | 1 |
| Acikel, M; Arslan, S; Atesal, S; Bozkurt, E; Erol, MK; Gundogdu, F; Senocak, H | 1 |
| Doughty, RN; White, HD | 1 |
| Köhnlein, T; Welte, T | 1 |
| Charlesworth, A; Cleland, JG; Di Lenarda, A; Lukas, MA; Metra, M; Poole-Wilson, PA; Remme, WJ; Scherhag, A; Spark, P; Swedberg, K; Torp-Pedersen, C | 1 |
| Book, WM; Doughan, AR; McConnell, ME | 1 |
| De Freitas, O; Fornoni, A; Lenz, O; Materson, BJ | 1 |
| Cleland, JG; Di Lenarda, A; Komajda, M; Lukas, MA; Metra, M; Moullet, C; Poole-Wilson, PA; Remme, WJ; Scherhag, A; Spark, P; Swedberg, K; Torp-Pedersen, C | 1 |
| Chizyński, K; Goch, JH; Maciejewski, M; Ptaszyński, P; Ruta, J | 1 |
| Guan, YY; Hua, SM; Lu, HH; Sheng, ZQ; Tao, GH; Yang, QC; Ye, BH; Zhang, L | 1 |
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| Bloch, W; Boelck, B; Brixius, K; Grafweg, S; Hoyer, F; Lu, R; Mehlhorn, U; Pott, C; Schwinger, RH | 1 |
| Chen, GW; Jiang, ZF; Lin, Y; Wang, LX; Wu, TG; Zhao, Q | 1 |
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| Earl, GL; Fitzpatrick, JM; Narula, J; Verbos-Kazanas, MA | 1 |
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| Bank, AJ; Gonzalez-Campoy, JM; Kaiser, DR; Kelly, AS; Thelen, AM | 1 |
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| Cleland, JG; Di Lenarda, A; Komajda, M; Lukas, MA; Metra, M; Moullet, C; Poole-Wilson, PA; Remme, W; Scherhag, A; Spark, P; Swedberg, K; Torp-Pedersen, C | 1 |
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| Go, AS; Gurwitz, JH; Hsu, J; Lane, K; Platt, R; Yang, J | 1 |
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| Hayashi, T; Ishii, T; Nishioka, T; Nose, K; Saitou, Y; Uemura, H | 1 |
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| Detry, MA; Johnson, MR; Moran, JJ; Sweitzer, NK; Vardeny, O | 1 |
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| Chen, H; Guo, CY; Li, HW; Li, ZZ; Shen, LH; Sun, T; Tang, CS | 1 |
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| Anzai, T; Ito, H; Kohno, T; Meguro, T; Nagatomo, Y; Ogawa, S; Yoshikawa, T | 1 |
| Remme, WJ | 1 |
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| Brum, PC; Mady, C; Medeiros, A; Salemi, VM; Sirvente, Rde A; Vanzelli, AS | 1 |
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| Azevedo, ER; Floras, JS; Kubo, T; Newton, GE; Parker, JD; Picton, P | 1 |
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| Kow, FP; Ong, HT | 1 |
| Christiansen, B; Dominguez, H; Falskov, B; Hermann, TS; Køber, L; Major-Pedersen, A; Rask-Madsen, C; Raunsø, J; Torp-Pedersen, C | 1 |
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| Aggarwal, V; Shore, S; Zolty, R | 1 |
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| Kaul, S; Le, DE; Leong-Poi, H; Micari, A; Pascotto, M; Sari, I | 1 |
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| Akpek, M; Kaya, EG; Kaya, MG; Lam, YY; Sarli, B; Topsakal, R; Yarlioglues, M | 1 |
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| Akcay, S; Ceyhan, BM; Dogan, A; Erdogan, D; Icli, A; Okutan, H; Ozaydin, M; Peker, O; Sutcu, R; Uysal, BA; Varol, E; Yucel, H | 1 |
| Akcay, S; Dogan, A; Erdogan, D; Icli, A; Okutan, H; Ozaydin, M; Peker, T; Uysal, BA; Varol, E; Yucel, H | 1 |
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| Abdelnoor, M; Arnesen, H; Enger, S; Gjesdal, K; Norseth, J; Pripp, AH; Tveit, A; Ulimoen, SR | 1 |
| Chen, C; Chen, Q; Chen, Y; Chu, M; Jiang, J; Pan, L; Qian, Y; Wang, D; Zhou, A | 1 |
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| Bocchi, EA; Böhm, M; Borer, JS; Ford, I; Komajda, M; Swedberg, K; Tavazzi, L | 1 |
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| Arnesen, H; Enger, S; Horjen, AW; Norseth, J; Seljeflot, I; Tveit, A; Ulimoen, SR | 1 |
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| Chen, CY; Huang, YB; Lin, TY | 1 |
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| Gislason, GH; Johansen, JB; Jøns, C; Nielsen, JC; Petersen, HH; Riahi, S; Ruwald, AC; Torp-Pedersen, C; Vinther, M | 1 |
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| Fujito, K; Kimura, K; Takayanagi, R; Yamada, Y | 1 |
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| Chen, CY; Huang, YB; Kuo, CC; Liao, KM; Lin, TY | 1 |
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| Tornvall, P; Y-Hassan, S | 1 |
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| Gislason, GH; Johansen, JB; Jøns, C; Nielsen, JC; Philbert, BT; Riahi, S; Ruwald, AC; Torp-Pedersen, C; Vinther, M | 1 |
| Cirillo, P; De Angelis, E; Esposito, G; Franzone, A; Gargiulo, G; Giugliano, G; Ilardi, F; Izzo, R; Menafra, G; Morisco, C; Paolillo, R; Perrino, C; Schiattarella, GG; Scudiero, L; Stabile, E; Trimarco, V | 1 |
| Casali, KR; Dartora, DR; Dias, LD; Eibel, B; Irigoyen, MC; Kalil, RAK; Kristochek, M; Lehnen, AM; Markoski, MM; Peres, TR | 1 |
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| Andrews, LM; Koch, BCP; van der Nagel, BCH; van Domburg, B | 1 |
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| Chen, YC; Du, CK; Edgley, AJ; Fujii, Y; Inagaki, T; Kelly, DJ; Ngo, JP; Ow, CPC; Pearson, JT; Shirai, M; Sonobe, T; Sukumaran, V; Thambyah, HP; Tsuchimochi, H; Umetani, K; Waddingham, MT; Zhan, DY | 1 |
| Fintel, DJ; Germano, JJ; Goldberger, JJ; Shani, J; Subacius, H; Zaatari, G | 1 |
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| Andersson, C; Gislason, GH; Kristensen, SL; Køber, L; Madelaire, C; Pierce, C; Schou, M; Schwartz, B; Torp-Pedersen, C | 1 |
| Biswas, A; Chen, X; Ghazi, L; Hanna, J; Li, F; Peixoto, AJ; Shah, T; Simonov, M; Wilson, FP; Yamamoto, Y | 1 |
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| Frey, N; Gampp, H; Hackbarth, J; Lugenbiel, P; Müller, ME; Petersenn, F; Pfeiffer, J; Rahm, AK; Rivinius, R; Thomas, D | 1 |
| Ashley, EA; Bernstein, D; Huang, Y; Kawana, M; Kirillova, A; Lane, KV; Parikh, VN; Perez, MV; Pruitt, BL; Seo, K; Wang, Q; Wheeler, MT; Wu, JC; Yadav, S; Yamamoto, Y | 1 |
| de Groot, LCPGM; Mathôt, RAA; Oliai Araghi, S; Ploegmakers, KJ; Seppala, LJ; Stricker, B; Swart, KMA; Uitterlinden, AG; van der Velde, N; van Dijk, SC; van Poelgeest, EP; van Schoor, NM | 1 |
83 review(s) available for carvedilol and metoprolol
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Effects of beta-blocker therapy on mortality in patients with heart failure. A systematic overview of randomized controlled trials.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Follow-Up Studies; Heart Failure; Humans; Metoprolol; Propanolamines; Randomized Controlled Trials as Topic; Survival Analysis; Treatment Outcome | 1997 |
[Beta blockers in heart failure. Experiences and recommendations for clinical use. ANMCO-Area Heart Failure].
Topics: Adrenergic beta-Antagonists; Aged; Bisoprolol; Carbazoles; Carvedilol; Controlled Clinical Trials as Topic; Follow-Up Studies; Heart Failure; Humans; Metoprolol; Propanolamines; Prospective Studies; Randomized Controlled Trials as Topic; Time Factors; Vasodilator Agents | 1998 |
Beta-blocker therapy in heart failure: pathophysiology and clinical results.
Topics: Adrenergic beta-Antagonists; Aged; Bisoprolol; Carbazoles; Carvedilol; Clinical Trials as Topic; Exercise; Heart Failure; Heart Rate; Hemodynamics; Humans; Imidazoles; Male; Metoprolol; Middle Aged; Propanolamines; Propranolol; Quality of Life; Stroke Volume; Time Factors; Vasodilator Agents; Xamoterol | 1999 |
[Drug therapy of chronic heart failure: when are beta receptor blockers indicated?].
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Antihypertensive Agents; Bisoprolol; Carbazoles; Carvedilol; Chronic Disease; Heart Failure; Hemodynamics; Humans; Meta-Analysis as Topic; Metoprolol; Placebos; Propanolamines; Randomized Controlled Trials as Topic; Risk Factors; Time Factors | 1999 |
Major beta blocker mortality trials in chronic heart failure: a critical review.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Bisoprolol; Carbazoles; Carvedilol; Female; Heart Failure; Humans; Male; Metoprolol; Morbidity; Multicenter Studies as Topic; Propanolamines; Prospective Studies; Randomized Controlled Trials as Topic; Ventricular Dysfunction, Left | 1999 |
Beta-adrenoceptor blockers in heart failure.
Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Heart Failure; Humans; Metoprolol; Propanolamines; Treatment Outcome | 1999 |
beta-adrenergic receptor blockade in chronic heart failure.
Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Chronic Disease; Heart Failure; Heart Function Tests; Humans; Metoprolol; Propanolamines; Receptors, Adrenergic, beta; Signal Transduction | 2000 |
The effect of beta-blockers on health-related quality of life in patients with heart failure.
Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Clinical Trials as Topic; Health Status; Heart Failure; Humans; Metoprolol; Propanolamines; Quality of Life | 2000 |
The impact of beta-blockade on mortality rates in patients with congestive heart failure.
Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Heart Failure; Humans; Meta-Analysis as Topic; Metoprolol; Patient Selection; Propanolamines; Randomized Controlled Trials as Topic; Risk Factors; Survival Analysis; Treatment Outcome | 2000 |
What type of beta-blocker should be used to treat chronic heart failure?
Topics: Adrenergic beta-Antagonists; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Humans; Metoprolol; Propanolamines; Ventricular Function, Left | 2000 |
Beta-adrenergic blockade in the treatment of congestive heart failure.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Heart Failure; Humans; Metoprolol; Propanolamines | 2000 |
Beta-blockers and spironolactone in heart failure.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Heart Failure; Humans; Metoprolol; Mineralocorticoid Receptor Antagonists; Propanolamines; Randomized Controlled Trials as Topic; Spironolactone; Treatment Outcome | 2000 |
Deactivation of the sympathetic nervous system in patients with chronic congestive heart failure.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Heart Failure; Humans; Metoprolol; Propanolamines; Receptors, Adrenergic; Signal Transduction; Sympathetic Nervous System; Ventricular Function, Left | 2000 |
Beta blockade in patients with congestive heart failure. Why, who, and how.
Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Contraindications; Heart Failure; Humans; Metoprolol; Patient Selection; Propanolamines; Ventricular Dysfunction, Left | 2000 |
Meta-analysis of effect of beta-blocker therapy on mortality in patients with New York Heart Association class IV chronic congestive heart failure.
Topics: Adrenergic beta-Antagonists; Benzopyrans; Bisoprolol; Carbazoles; Carvedilol; Ethanolamines; Heart Failure; Humans; Metoprolol; Nebivolol; Propanolamines | 2000 |
Beta blockers and congestive heart failure.
Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Heart Failure; Humans; Meta-Analysis as Topic; Metoprolol; Propanolamines; Randomized Controlled Trials as Topic; Risk; Severity of Illness Index; Stroke Volume; Systole; Treatment Outcome | 2000 |
The importance of beta blockers in the treatment of heart failure.
Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Contraindications; Drug Administration Schedule; Female; Heart Failure; Humans; Male; Metoprolol; Patient Selection; Propanolamines; Randomized Controlled Trials as Topic; Severity of Illness Index | 2000 |
Influence of beta-blockers on mortality in chronic heart failure.
Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Chronic Disease; Heart Failure; Humans; Metoprolol; Morbidity; Propanolamines; Randomized Controlled Trials as Topic; Treatment Outcome | 2000 |
Economic impact of beta blockade in heart failure.
Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Clinical Trials as Topic; Cost-Benefit Analysis; Drug Costs; Heart Failure; Humans; Metoprolol; Models, Economic; Propanolamines; Sensitivity and Specificity; United States | 2001 |
Comparative effects of carvedilol and metoprolol on left ventricular ejection fraction in heart failure: results of a meta-analysis.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Heart Failure; Humans; Metoprolol; Propanolamines; Randomized Controlled Trials as Topic; Ventricular Function, Left | 2001 |
Beta-blockers to reduce mortality in patients with systolic dysfunction: a meta-analysis.
Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Heart Failure; Hemodynamics; Humans; Metoprolol; Propanolamines; Research Design; Risk Factors; Severity of Illness Index; Systole; Treatment Outcome | 2001 |
[Adrenergic beta inhibitors in heart insufficiency: which and when?].
Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Heart Failure; Humans; Metoprolol; Patient Selection; Propanolamines; Randomized Controlled Trials as Topic; Sympathetic Nervous System; Ventricular Dysfunction, Left | 2001 |
[Role of beta-blockers in the treatment of chronic heart heart failure].
Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Chronic Disease; Controlled Clinical Trials as Topic; Disease Progression; Drug Administration Schedule; Heart Failure; Humans; Metoprolol; Myocardial Contraction; Patient Selection; Propanolamines; Survival Rate; Ventricular Dysfunction, Left; Ventricular Function, Left | 2001 |
Beta-blockers in heart failure.
Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Heart Failure; Humans; Metoprolol; Propanolamines | 2001 |
[Treatment of heart failure: an update].
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antidiuretic Hormone Receptor Antagonists; Antihypertensive Agents; Benzazepines; Bosentan; Carbazoles; Carvedilol; Death, Sudden, Cardiac; Defibrillators, Implantable; Double-Blind Method; Heart Failure; Heart-Assist Devices; Humans; Metoprolol; Multicenter Studies as Topic; Placebos; Propanolamines; Prospective Studies; Pyridines; Quality of Life; Randomized Controlled Trials as Topic; Sulfonamides; Tetrazoles; Valine; Valsartan; Vasodilator Agents | 2002 |
[Prevention and treatment of congestive heart failure in diabetic patients].
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Carbazoles; Cardiotonic Agents; Carvedilol; Clinical Trials as Topic; Coronary Disease; Diabetes Complications; Diabetes Mellitus, Type 2; Female; Heart Failure; Humans; Hypertension; Hypertrophy, Left Ventricular; Lisinopril; Male; Meta-Analysis as Topic; Metoprolol; Prognosis; Propanolamines; Risk Factors; Time Factors | 2002 |
Should beta-blockers be used for the treatment of pediatric patients with chronic heart failure?
Topics: Adolescent; Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Child; Child, Preschool; Chronic Disease; Clinical Trials as Topic; Heart Failure; Humans; Infant; Infant, Newborn; Metoprolol; Propanolamines; Propranolol; Treatment Outcome | 2002 |
[Use of beta-blockers in heart failure].
Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Clinical Trials as Topic; Contraindications; Heart Failure; Humans; Metoprolol; Propanolamines | 2003 |
Beta-blocker benefit according to severity of heart failure.
Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Chronic Disease; Heart Failure; Hospitalization; Humans; Metoprolol; Propanolamines; Risk Assessment; Risk Factors; Severity of Illness Index; Stroke Volume; Survival Analysis; Treatment Outcome | 2003 |
Use of beta-blockers in congestive heart failure.
Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; Forecasting; Heart Failure; Humans; Metoprolol; Propanolamines; Randomized Controlled Trials as Topic | 2003 |
Choosing metoprolol or carvedilol in heart failure (a pre-COMET commentary).
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Clinical Trials as Topic; Exercise; Heart Failure; Hemodynamics; Humans; Metoprolol; Middle Aged; Outcome Assessment, Health Care; Patient Selection; Propanolamines; Rest; Retrospective Studies | 2003 |
Beta-blockers for chronic heart failure: surviving longer but feeling better?
Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Exercise Test; Exercise Tolerance; Heart Failure; Humans; Metoprolol; Propanolamines; Quality of Life | 2003 |
Myocardial beta-1 adrenoceptor down-regulation in aging and heart failure: implications for beta-blocker use in older adults with heart failure.
Topics: Adrenergic beta-Antagonists; Aging; Carbazoles; Carvedilol; Down-Regulation; Heart Failure; Hemodynamics; Humans; Metoprolol; Propanolamines; Receptors, Adrenergic, beta-1; Vasoconstriction | 2003 |
Do beta-blockers prolong survival in heart failure only by inhibiting the beta1-receptor? A perspective on the results of the COMET trial.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Chronic Disease; Controlled Clinical Trials as Topic; Europe; Heart Failure; Humans; Metoprolol; Propanolamines; Receptors, Adrenergic, beta-1; Risk Factors; Survival Analysis | 2003 |
Selective versus nonselective beta-blockade for heart failure therapy: are there lessons to be learned from the COMET trial?
Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; Europe; Heart Failure; Humans; Metoprolol; Propanolamines; Receptors, Adrenergic, beta-1; Risk Factors; Sympathetic Nervous System; Ventricular Dysfunction, Left | 2003 |
A clinical pharmacologist's response to Dr Milton Packer's perspective on the results of the COMET trial.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Europe; Heart Failure; Humans; Metoprolol; Multicenter Studies as Topic; Pharmacology, Clinical; Propanolamines; Randomized Controlled Trials as Topic; Treatment Outcome | 2003 |
[Genetic polymorphisms in drug metabolizing enzymes--impact on treatment with beta-blockers].
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alleles; Atenolol; Benzopyrans; Biotransformation; Bisoprolol; Carbazoles; Carvedilol; Clinical Trials as Topic; Cytochrome P-450 CYP2D6; Ethanolamines; Female; Genotype; Humans; Male; Metoprolol; Mutation; Nebivolol; Pharmacogenetics; Phenotype; Polymorphism, Genetic; Propanolamines; Risk Factors; Time Factors | 2004 |
The update on the rationale, use and selection of beta-blockers in heart failure.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Heart Failure; Humans; Metoprolol; Propanolamines; Treatment Outcome | 2004 |
Ventricular remodeling in heart failure and the effect of beta-blockade.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Heart Failure; Humans; Metoprolol; Propanolamines; Randomized Controlled Trials as Topic; Ventricular Dysfunction, Left; Ventricular Remodeling | 2004 |
Advantages of a third-generation beta-blocker in patients with diabetes mellitus.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Coronary Disease; Diabetes Complications; Humans; Metoprolol; Propanolamines; Randomized Controlled Trials as Topic | 2004 |
Methods of assessing the functional status of patients with left ventricular systolic dysfunction in interventional studies: can brain natriuretic peptide measurement be used as surrogate for the traditional methods?
Topics: Angiotensin-Converting Enzyme Inhibitors; Biomarkers; Carbazoles; Carvedilol; Clinical Trials as Topic; Data Collection; Drug Administration Schedule; Enalapril; Exercise Test; Exercise Tolerance; Health Status; Heart Failure; Humans; Imidazolidines; Meta-Analysis as Topic; Metoprolol; Natriuretic Peptide, Brain; Propanolamines; Quality of Life; Statistics as Topic; Treatment Outcome; Ventricular Dysfunction, Left | 2004 |
Pharmacodynamics of beta-blockers in heart failure: lessons from the carvedilol or metoprolol European trial.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Heart Failure; Humans; Metoprolol; Propanolamines; Research Design | 2004 |
Use of beta-blockers in older adults with chronic heart failure.
Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Carbazoles; Cardiovascular System; Carvedilol; Chronic Disease; Clinical Trials as Topic; Heart Failure; Hospitalization; Humans; Metoprolol; Myocardial Infarction; Propanolamines; Risk; Systole | 2004 |
The effects of beta blockers on morbidity and mortality in heart failure.
Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Heart Failure; Humans; Metoprolol; Morbidity; Multicenter Studies as Topic; Propanolamines; Randomized Controlled Trials as Topic; Survival Analysis; United States | 2004 |
Pharmacokinetics and pharmacodynamics of beta blockers in heart failure.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; Heart Failure; Humans; Metoprolol; Propanolamines; Randomized Controlled Trials as Topic; Ventricular Dysfunction, Left | 2004 |
Beta blockers as anti-arrhythmic agents.
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Carbazoles; Carvedilol; Heart Failure; Humans; Metoprolol; Propanolamines; Randomized Controlled Trials as Topic; United States | 2004 |
Critical differences among beta-adrenoreceptor antagonists in myocardial failure: debating the MERIT of COMET.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Heart Failure; Humans; Metoprolol; Propanolamines; Randomized Controlled Trials as Topic | 2005 |
Emerging trends in the management of heart failure: Beta blocker therapy.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Bisoprolol; Carbazoles; Carvedilol; Clinical Trials as Topic; Cost of Illness; Diuretics; Drug Costs; Drug Therapy, Combination; Heart Failure; Humans; Metoprolol; Morbidity; Natriuretic Peptides; Nurse's Role; Patient Selection; Practice Guidelines as Topic; Propanolamines; Quality of Life; Renin-Angiotensin System; Severity of Illness Index; Sympathetic Nervous System; Treatment Outcome | 2005 |
[Beta blockers for therapy of chronic heart failure].
Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Chronic Disease; Clinical Trials as Topic; Heart Failure; Humans; Metoprolol; Propanolamines | 2005 |
[Congestive heart failure in Spain: cost-effectiveness and cost-benefit analyses of treatment with beta-blockers].
Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Cost-Benefit Analysis; Heart Failure; Humans; Metoprolol; Propanolamines; Randomized Controlled Trials as Topic; Spain | 2005 |
Drug and drug-device therapy in heart failure patients in the post-COMET and SCD-HeFT era.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme 2; Anti-Arrhythmia Agents; Carbazoles; Carvedilol; Death, Sudden, Cardiac; Defibrillators, Implantable; Heart Failure; Humans; Metoprolol; Peptidyl-Dipeptidase A; Propanolamines; Ventricular Dysfunction, Left | 2005 |
A review of carvedilol arrhythmia data in clinical trials.
Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Bisoprolol; Carbazoles; Carvedilol; Death, Sudden, Cardiac; Digoxin; Heart Failure; Humans; Metoprolol; Myocardial Infarction; Propanolamines; Randomized Controlled Trials as Topic | 2005 |
Beta-blockers in heart failure: is more better?
Topics: Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; Heart Failure; Humans; Losartan; Metoprolol; Propanolamines; Prospective Studies; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Sympathetic Nervous System | 2004 |
Early initiation of beta blockade in heart failure: issues and evidence.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Heart Failure; Humans; Hypertension; Metoprolol; Propanolamines; Ventricular Function; Ventricular Remodeling | 2005 |
[Beta-adrenolytics in heart failure--are they all really equal?].
Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Heart Failure; Humans; Metoprolol; Propanolamines | 2005 |
Mapping the journey.
Topics: Adrenergic beta-Antagonists; Carbazoles; Cardiac Output, Low; Carvedilol; Humans; Metoprolol; Propanolamines; Quality of Life | 2006 |
Metabolic effects of beta-adrenoceptor antagonists with special emphasis on carvedilol.
Topics: Adrenergic beta-Antagonists; Animals; Carbazoles; Carvedilol; Diabetes Mellitus; Glucose; Humans; Insulin Resistance; Metoprolol; Propanolamines | 2006 |
Carvedilol: use in chronic heart failure.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Carbazoles; Carvedilol; Diabetic Angiopathies; Drug Therapy, Combination; Heart Failure; Heart Rate; Humans; Metoprolol; Myocardial Infarction; Propanolamines; Randomized Controlled Trials as Topic; Renal Insufficiency; Stroke Volume; Treatment Outcome; Ventricular Dysfunction, Left; Ventricular Function, Left | 2007 |
The use of metoprolol CR/XL in the treatment of patients with diabetes and chronic heart failure.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Chronic Disease; Delayed-Action Preparations; Diabetes Complications; Female; Heart Failure; Humans; Male; Metoprolol; Practice Guidelines as Topic; Propanolamines; Randomized Controlled Trials as Topic; Research Design; Treatment Outcome | 2006 |
Are there clinically important differences between beta-blockers in heart failure?
Topics: Adrenergic beta-Antagonists; Blood Pressure; Carbazoles; Carvedilol; Dosage Forms; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation; Heart; Heart Failure; Heart Rate; Humans; Metoprolol; Propanolamines; Survival Analysis; Treatment Outcome | 2005 |
[COMET: metoprolol].
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Heart Failure; Humans; Metoprolol; Propanolamines; Randomized Controlled Trials as Topic | 2007 |
[Beta blockers: characteristics, mechanisms of action, pharmacokinetics, indication, contraindication, clinical data, and side effects].
Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Clinical Trials as Topic; Contraindications; Heart Failure; Humans; Metoprolol; Propanolamines | 2007 |
Carvedilol in the treatment of chronic heart failure: lessons from the Carvedilol Or Metoprolol European Trial.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Europe; Heart Failure; Humans; Metoprolol; Propanolamines; Randomized Controlled Trials as Topic; Treatment Outcome | 2007 |
Resting heart rate in cardiovascular disease.
Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Carbazoles; Cardiac Output, Low; Cardiovascular Diseases; Carvedilol; Coronary Artery Disease; Coronary Disease; Exercise Test; Heart Rate; Humans; Metoprolol; Multivariate Analysis; Myocardial Infarction; Myocardial Ischemia; Prognosis; Propanolamines; Risk Assessment; Risk Factors; Timolol; Ventricular Dysfunction, Left | 2007 |
Switching to once-daily evidence-based [beta]-blockers in patients with systolic heart failure or left ventricular dysfunction after myocardial infarction.
Topics: Adrenergic beta-Antagonists; Algorithms; Carbazoles; Carvedilol; Delayed-Action Preparations; Evidence-Based Medicine; Heart Failure, Systolic; Humans; Metoprolol; Myocardial Infarction; Patient Compliance; Polypharmacy; Propanolamines; Therapeutic Equivalency; Ventricular Dysfunction, Left | 2007 |
Beta-blockers in heart failure: how far have we progressed?
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Bisoprolol; Carbazoles; Carvedilol; Contraindications; Heart Failure; Humans; Metoprolol; Propanolamines; Sympathetic Nervous System; Ventricular Dysfunction, Left | 2002 |
Consistency of ss-blocker effect across various subgroups with heart failure: insights from the MERIT-HF trial.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Carbazoles; Carvedilol; Heart Failure; Humans; Metoprolol; Propanolamines; Risk; Treatment Outcome; United States | 2002 |
Use of beta-blockers for heart failure in patients with diabetes mellitus.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Bisoprolol; Carbazoles; Carvedilol; Diabetes Complications; Diabetes Mellitus; Heart Failure; Humans; Metoprolol; Propanolamines; United States | 2002 |
Carvedilol: a third-generation β-blocker should be a first-choice β-blocker.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Atenolol; Biomarkers; Carbazoles; Carvedilol; Humans; Hypertension; Metoprolol; Myocardial Infarction; Propanolamines; Secondary Prevention; Sympathetic Nervous System; Vasodilator Agents | 2012 |
β-Blockers in heart failure: benefits of β-blockers according to varying male proportions of study patients.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Bisoprolol; Carbazoles; Carvedilol; China; Heart Failure; Hospitalization; Humans; Male; Metoprolol; Propanolamines; Statistics as Topic; Vasodilator Agents | 2012 |
Meta-analysis of carvedilol versus beta 1 selective beta-blockers (atenolol, bisoprolol, metoprolol, and nebivolol).
Topics: Adrenergic beta-1 Receptor Antagonists; Atenolol; Benzopyrans; Bisoprolol; Carbazoles; Carvedilol; Ethanolamines; Global Health; Humans; Metoprolol; Myocardial Infarction; Nebivolol; Platelet Aggregation Inhibitors; Propanolamines; Survival Rate; Treatment Outcome | 2013 |
Meta-analysis comparing carvedilol versus metoprolol for the prevention of postoperative atrial fibrillation following coronary artery bypass grafting.
Topics: Adrenergic alpha-1 Receptor Antagonists; Anti-Arrhythmia Agents; Atrial Fibrillation; Carbazoles; Carvedilol; Coronary Artery Bypass; Coronary Artery Disease; Humans; Metoprolol; Postoperative Period; Propanolamines; Treatment Outcome | 2014 |
β-blockers: a review of their pharmacological and physiological diversity in hypertension.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Atenolol; Benzopyrans; Blood Pressure; Carbazoles; Carvedilol; Ethanolamines; Humans; Hypertension; Metoprolol; Nebivolol; Propanolamines | 2014 |
Effects of beta-blockers for congestive heart failure in pediatric and congenital heart disease patients: a meta-analysis of published studies.
Topics: Adrenergic beta-Antagonists; Age Factors; Bisoprolol; Carbazoles; Carvedilol; Child; Heart Defects, Congenital; Heart Failure; Humans; Metoprolol; Propanolamines; Ventricular Dysfunction, Left | 2015 |
Meta-analysis of the effects of carvedilol versus metoprolol on all-cause mortality and hospitalizations in patients with heart failure.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Cause of Death; Global Health; Heart Failure; Hospitalization; Humans; Metoprolol; Prevalence; Prognosis; Propanolamines; Survival Rate | 2015 |
Impact of CYP2D6 Genetic Variation on the Response of the Cardiovascular Patient to Carvedilol and Metoprolol.
Topics: Adrenergic alpha-Antagonists; Animals; Carbazoles; Cardiovascular Diseases; Carvedilol; Cytochrome P-450 CYP2D6; Genetic Variation; Humans; Metoprolol; Pharmacogenetics; Propanolamines; Treatment Outcome | 2015 |
Beta-blockers for congestive heart failure in children.
Topics: Adolescent; Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Child; Child, Preschool; Heart Failure; Humans; Infant; Infant, Newborn; Metoprolol; Propanolamines; Propranolol; Randomized Controlled Trials as Topic | 2016 |
[The benefits of carvedilol therapy in the treatment of patients with high cardiovascular risk].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Antihypertensive Agents; Bisoprolol; Carbazoles; Cardiovascular Diseases; Carvedilol; Clinical Trials as Topic; Drug Prescriptions; Evidence-Based Medicine; Heart Failure; Hemodynamics; Humans; Hungary; Hypertension; Metoprolol; Multicenter Studies as Topic; Oxidative Stress; Primary Health Care; Propanolamines; Risk | 2016 |
Meta-Analysis Comparing Metoprolol and Carvedilol on Mortality Benefits in Patients With Acute Myocardial Infarction.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-1 Receptor Antagonists; Aged; Carbazoles; Carvedilol; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Propanolamines | 2017 |
Genetic Variation of Hepatic Enzymes Influence on β-Blocker Dose in Patients With Reduced Ejection Fraction Heart Failure.
Topics: Adrenergic beta-Antagonists; Bisoprolol; Carvedilol; Cytochrome P-450 CYP2D6; Genetic Variation; Heart Failure; Humans; Metoprolol; Research Design; Treatment Outcome | 2020 |
Outcomes of beta blocker use in cocaine-associated chest pain: a meta-analysis.
Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Atenolol; Bisoprolol; Carvedilol; Cocaine; Humans; Metoprolol; Propanolamines; Propranolol | 2018 |
Beta-blockers for congestive heart failure in children.
Topics: Adolescent; Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Child; Child, Preschool; Heart Failure; Heart Transplantation; Humans; Infant; Infant, Newborn; Metoprolol; Propanolamines; Propranolol; Randomized Controlled Trials as Topic; Stroke Volume | 2020 |
131 trial(s) available for carvedilol and metoprolol
| Article | Year |
|---|---|
Comparison of the antihypertensive effects of carvedilol and metoprolol on resting and exercise blood pressure.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Blood Pressure; Carbazoles; Carvedilol; Double-Blind Method; Exercise Test; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged; Propanolamines; Vasodilator Agents | 1992 |
The use of carvedilol in elderly hypertensive patients.
Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Aged, 80 and over; Blood Pressure; Carbazoles; Carvedilol; Female; Half-Life; Heart Rate; Humans; Hypertension; Lipids; Male; Metoprolol; Middle Aged; Multicenter Studies as Topic; Nitrendipine; Pindolol; Propanolamines; Random Allocation; Single-Blind Method | 1990 |
Circadian antihypertensive profile of carvedilol (BM 14190).
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Body Weight; Carbazoles; Carvedilol; Circadian Rhythm; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged; Physical Exertion; Propanolamines; Random Allocation | 1987 |
Effect of carvedilol and metoprolol on blood pressure, blood flow, and vascular resistance.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Flow Velocity; Blood Pressure; Carbazoles; Carvedilol; Double-Blind Method; Forearm; Hemodynamics; Humans; Hypertension; Metoprolol; Middle Aged; Plethysmography; Propanolamines; Random Allocation; Vascular Resistance | 1987 |
Follow-up of a method of twenty-four-hour indirect blood pressure monitoring: evaluation of carvedilol, a new antihypertensive agent.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Carbazoles; Carvedilol; Clinical Trials as Topic; Double-Blind Method; Drug Administration Schedule; Exercise Test; Female; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged; Monitoring, Physiologic; Propanolamines; Random Allocation | 1987 |
Systemic and renal hemodynamic responses to carvedilol and metoprolol in hypertensive renal transplant patients.
Topics: Adrenergic beta-Antagonists; Adult; Carbazoles; Carvedilol; Double-Blind Method; Female; Glomerular Filtration Rate; Hemodynamics; Humans; Hypertension, Renal; Kidney Transplantation; Male; Metoprolol; Middle Aged; Propanolamines | 1993 |
Reproducibility and consistency of the responses to supine bicycle ergometry; evaluation in conjunction with beta 1-adrenoceptor occupancies.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Blood Pressure; Carbazoles; Carvedilol; Celiprolol; Epinephrine; Exercise Test; Heart Rate; Humans; Male; Metoprolol; Norepinephrine; Propanolamines; Propranolol; Radioligand Assay; Receptors, Adrenergic, beta; Reproducibility of Results | 1994 |
Differential effect of chronic treatment with two beta-blocking agents on insulin sensitivity: the carvedilol-metoprolol study.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Carbazoles; Carvedilol; Double-Blind Method; Female; Heart Rate; Humans; Insulin; Insulin Resistance; Lipids; Male; Metoprolol; Middle Aged; Propanolamines | 1996 |
Comparison of the hemodynamic effects of metoprolol and carvedilol in hypertensive patients.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Blood Pressure; Carbazoles; Cardiac Output; Carvedilol; Female; Hemodynamics; Humans; Hypertension; Male; Metoprolol; Middle Aged; Propanolamines; Single-Blind Method; Vascular Resistance | 1996 |
Comparative hemodynamic, left ventricular functional, and antiadrenergic effects of chronic treatment with metoprolol versus carvedilol in the failing heart.
Topics: Adrenergic beta-Antagonists; Adult; Carbazoles; Cardiac Output, Low; Carvedilol; Electrocardiography, Ambulatory; Female; Heart Rate; Hemodynamics; Humans; Male; Metoprolol; Middle Aged; Physical Exertion; Propanolamines; Receptors, Adrenergic, beta; Ventricular Function, Left | 1996 |
Second- and third-generation beta-blocking drugs in chronic heart failure.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Carbazoles; Cardiac Output, Low; Cardiomyopathy, Dilated; Carvedilol; Chronic Disease; Exercise Test; Heart Ventricles; Hemodynamics; Humans; Metoprolol; Middle Aged; Myocardial Ischemia; Oxygen Consumption; Propanolamines; Ventricular Function, Left | 1997 |
Hemodynamic differences between metoprolol and carvedilol in hypertensive patients.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Carbazoles; Cardiac Output; Carvedilol; Dose-Response Relationship, Drug; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Metoprolol; Middle Aged; Propanolamines; Single-Blind Method; Vascular Resistance | 1998 |
Randomized, double-blind, placebo-controlled study of carvedilol on the prevention of nitrate tolerance in patients with chronic heart failure.
Topics: Adrenergic Antagonists; Aged; Blood Flow Velocity; Blood Platelets; Blood Pressure; Carbazoles; Carvedilol; Chronic Disease; Cyclic GMP; Double-Blind Method; Doxazosin; Drug Hypersensitivity; Drug Therapy, Combination; Female; Follow-Up Studies; Forearm; Heart Failure; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Nitroglycerin; Propanolamines; Vasodilator Agents | 1998 |
Comparison of safety and efficacy of carvedilol and metoprolol in stable angina pectoris.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Age Factors; Aged; Angina Pectoris; Antioxidants; Carbazoles; Carvedilol; Double-Blind Method; Electrocardiography; Exercise Test; Female; Follow-Up Studies; Humans; Male; Metoprolol; Middle Aged; Myocardial Ischemia; Placebos; Propanolamines; Risk Factors; Safety; Single-Blind Method; Time Factors; Vasodilator Agents | 1999 |
Prospective, randomized comparison of effect of long-term treatment with metoprolol or carvedilol on symptoms, exercise, ejection fraction, and oxidative stress in heart failure.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Carbazoles; Cardiac Output, Low; Carvedilol; Chronic Disease; Exercise; Female; Humans; Male; Metoprolol; Middle Aged; Oxidative Stress; Propanolamines; Prospective Studies; Stroke Volume; Thiobarbituric Acid Reactive Substances | 1999 |
Long-term effects of carvedilol in idiopathic dilated cardiomyopathy with persistent left ventricular dysfunction despite chronic metoprolol. The Heart-Muscle Disease Study Group.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Cross-Over Studies; Drug Therapy, Combination; Echocardiography, Doppler; Electrocardiography, Ambulatory; Exercise Test; Follow-Up Studies; Heart Ventricles; Humans; Metoprolol; Myocardial Contraction; Oxygen Consumption; Propanolamines; Quality of Life; Retrospective Studies; Treatment Outcome; Ventricular Dysfunction, Left | 1999 |
Beta-blockade in heart failure: a comparison of carvedilol with metoprolol.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Blood Pressure; Carbazoles; Carvedilol; Double-Blind Method; Exercise Test; Female; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Prospective Studies; Ventricular Function, Left | 1999 |
Differential effects of beta-blockers in patients with heart failure: A prospective, randomized, double-blind comparison of the long-term effects of metoprolol versus carvedilol.
Topics: Adrenergic beta-Antagonists; Blood Pressure; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Female; Heart Failure; Heart Rate; Hemodynamics; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Stroke Volume; Vascular Resistance; Ventricular Function, Left | 2000 |
Antioxidant properties of carvedilol and metoprolol in heart failure: a double-blind randomized controlled trial.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Analysis of Variance; Antioxidants; Carbazoles; Carvedilol; Double-Blind Method; Female; Glutathione Peroxidase; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Superoxide Dismutase | 2001 |
Differing beta-blocking effects of carvedilol and metoprolol.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Blood Pressure; Carbazoles; Carvedilol; Cross-Over Studies; Double-Blind Method; Exercise Test; Heart Failure; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Reference Values | 2001 |
Prospective crossover comparison of carvedilol and metoprolol in patients with chronic heart failure.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Chronic Disease; Cross-Over Studies; Female; Heart Failure; Hemodynamics; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Prospective Studies; Stroke Volume; Ventricular Function, Left | 2001 |
Nonselective versus selective beta-adrenergic receptor blockade in congestive heart failure: differential effects on sympathetic activity.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Blood Pressure; Carbazoles; Carvedilol; Chronic Disease; Double-Blind Method; Drug Administration Schedule; Heart Failure; Heart Rate; Humans; Metoprolol; Middle Aged; Muscle, Skeletal; Norepinephrine; Propanolamines; Receptors, Adrenergic, beta; Substrate Specificity; Sympathetic Nervous System | 2001 |
Lack of evidence for peripheral alpha(1)- adrenoceptor blockade during long-term treatment of heart failure with carvedilol.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adrenergic Fibers; Carbazoles; Carvedilol; Chronic Disease; Double-Blind Method; Drug Monitoring; Evidence-Based Medicine; Exercise Test; Female; Fourier Analysis; Hand Strength; Heart Failure; Hemodynamics; Humans; Isometric Contraction; Long-Term Care; Male; Metoprolol; Middle Aged; Muscle, Skeletal; Neuroeffector Junction; Prognosis; Propanolamines; Stroke Volume; Time Factors; Vasoconstriction; Vasodilator Agents | 2001 |
Comparative left ventricular functional and neurohumoral effects of chronic treatment with carvedilol versus metoprolol in patients with dilated cardiomyopathy.
Topics: 3-Iodobenzylguanidine; Adrenergic beta-Antagonists; Adult; Atrial Natriuretic Factor; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Chronic Disease; Female; Hemodynamics; Humans; Male; Metoprolol; Middle Aged; Natriuretic Peptide, Brain; Neurotransmitter Agents; Norepinephrine; Propanolamines; Therapeutic Equivalency; Tomography, Emission-Computed, Single-Photon; Ventricular Function, Left | 2001 |
Comparison of effects of carvedilol versus metoprolol on cytokine levels in patients with idiopathic dilated cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Cytokines; Female; Humans; Interleukin-6; Male; Metoprolol; Middle Aged; Propanolamines; Tumor Necrosis Factor-alpha | 2002 |
Myocardial gene expression in dilated cardiomyopathy treated with beta-blocking agents.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Calcium-Transporting ATPases; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Female; Gene Expression; Hemodynamics; Humans; Male; Metoprolol; Middle Aged; Myocardium; Myosin Heavy Chains; Propanolamines; Receptors, Adrenergic, beta; RNA, Messenger; Stroke Volume; Ventricular Myosins | 2002 |
Rationale and design of the carvedilol or metoprolol European trial in patients with chronic heart failure: COMET.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Double-Blind Method; Europe; Female; Heart Failure; Humans; Male; Metoprolol; Patient Selection; Propanolamines; Research Design | 2002 |
Is beta-blockade useful in heart failure patients with atrial fibrillation? An analysis of data from two previously completed prospective trials.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Atrial Fibrillation; Carbazoles; Carvedilol; Chronic Disease; Comorbidity; Double-Blind Method; Female; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Prospective Studies; Stroke Volume; Treatment Outcome; Ventricular Function, Left | 2002 |
Beta-blocker therapy influences the hemodynamic response to inotropic agents in patients with heart failure: a randomized comparison of dobutamine and enoximone before and after chronic treatment with metoprolol or carvedilol.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aged; Carbazoles; Cardiotonic Agents; Carvedilol; Chronic Disease; Dobutamine; Drug Interactions; Drug Therapy, Combination; Enoximone; Female; Heart Failure; Hemodynamics; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Radionuclide Angiography; Severity of Illness Index; Time Factors; Treatment Outcome | 2002 |
Effects of long-term beta-blocker (metoprolol or carvedilol) therapy on QT variability in subjects with chronic heart failure secondary to ischemic cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Carbazoles; Carvedilol; Female; Heart Failure; Humans; Italy; Male; Metoprolol; Middle Aged; Propanolamines; Risk Factors; Severity of Illness Index; Single-Blind Method; Tilt-Table Test; Treatment Outcome | 2002 |
Use of thallium-201 myocardial scintigraphy for the prediction of the response to beta-blocker therapy in patients with dilated cardiomyopathy.
Topics: 3-Iodobenzylguanidine; Adrenergic beta-Antagonists; Adult; Aged; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Female; Forecasting; Heart; Hemodynamics; Humans; Male; Metoprolol; Middle Aged; Multivariate Analysis; Probability; Propanolamines; Radionuclide Imaging; Radiopharmaceuticals; Thallium Radioisotopes; Treatment Outcome | 2002 |
Coordinate changes in Myosin heavy chain isoform gene expression are selectively associated with alterations in dilated cardiomyopathy phenotype.
Topics: Antihypertensive Agents; Atrial Natriuretic Factor; Biopsy; Calcium-Transporting ATPases; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Catecholamines; Disease Progression; Female; Gene Expression; Heart Ventricles; Humans; Male; Metoprolol; Middle Aged; Myocardium; Myosin Heavy Chains; Phenotype; Propanolamines; Protein Isoforms; Radionuclide Imaging; Receptors, Adrenergic, beta; RNA, Messenger; Sarcoplasmic Reticulum; Ventricular Function, Left | 2002 |
Clinical outcomes in patients on beta-blocker therapy admitted with worsening chronic heart failure.
Topics: Adrenergic beta-Antagonists; Aged; Carbazoles; Cardiotonic Agents; Carvedilol; Double-Blind Method; Drug Therapy, Combination; Female; Heart Failure; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Milrinone; Propanolamines; Stroke Volume; Treatment Outcome | 2003 |
Vasopressor response to angiotensin II infusion in patients with chronic heart failure receiving beta-blockers.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Carbazoles; Carvedilol; Chronic Disease; Diuretics; Dose-Response Relationship, Drug; Female; Heart Failure; Humans; Infusions, Intravenous; Male; Metoprolol; Middle Aged; Propanolamines | 2003 |
Different responses to dobutamine in the presence of carvedilol or metoprolol in patients with chronic heart failure.
Topics: Adrenergic beta-Antagonists; Carbazoles; Cardiotonic Agents; Carvedilol; Chronic Disease; Cross-Over Studies; Dobutamine; Dopamine; Echocardiography, Stress; Heart Failure; Humans; Metoprolol; Middle Aged; Propanolamines; Single-Blind Method; Treatment Outcome | 2003 |
Beta-blocker benefit according to severity of heart failure.
Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Chronic Disease; Heart Failure; Hospitalization; Humans; Metoprolol; Propanolamines; Risk Assessment; Risk Factors; Severity of Illness Index; Stroke Volume; Survival Analysis; Treatment Outcome | 2003 |
Comparison of carvedilol and metoprolol on clinical outcomes in patients with chronic heart failure in the Carvedilol Or Metoprolol European Trial (COMET): randomised controlled trial.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Cause of Death; Double-Blind Method; Female; Follow-Up Studies; Heart Failure; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Treatment Outcome | 2003 |
Effect of beta-blockers on insulin resistance in patients with dilated cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Echocardiography; Female; Hemodynamics; Humans; Insulin Resistance; Male; Metoprolol; Middle Aged; Osmolar Concentration; Propanolamines; Tumor Necrosis Factor-alpha | 2003 |
Comparative effects of carvedilol and metoprolol on regional vascular responses to adrenergic stimuli in normal subjects and patients with chronic heart failure.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Atrial Natriuretic Factor; Carbazoles; Carvedilol; Chronic Disease; Dose-Response Relationship, Drug; Drug Administration Schedule; Exercise; Female; Forearm; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Muscle, Skeletal; Natriuretic Peptide, Brain; Norepinephrine; Propanolamines; Prospective Studies; Reference Values; Regional Blood Flow; Vascular Resistance; Vasodilator Agents; Vasomotor System | 2003 |
Effect of beta blockade (carvedilol or metoprolol) on activation of the renin-angiotensin-aldosterone system and natriuretic peptides in chronic heart failure.
Topics: Adrenergic beta-Antagonists; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Atrial Natriuretic Factor; Carbazoles; Carvedilol; Drug Therapy, Combination; Heart Failure; Humans; Metoprolol; Natriuretic Peptide, Brain; Propanolamines; Renin; Ventricular Function, Left | 2003 |
Effects of cold exposure on submaximal exercise performance and adrenergic activation in patients with congestive heart failure and the effects of beta-adrenergic blockade (carvedilol or metoprolol).
Topics: Adrenergic beta-Antagonists; Aged; Blood Gas Analysis; Carbazoles; Carvedilol; Case-Control Studies; Cold Temperature; Dyspnea; Exercise Test; Exercise Tolerance; Female; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Norepinephrine; Physical Endurance; Propanolamines; Prospective Studies; Receptors, Adrenergic; Single-Blind Method; Stroke Volume | 2003 |
Efficacy of carvedilol treatment on cardiac function and cardiac sympathetic nerve activity in patients with dilated cardiomyopathy: comparison with metoprolol therapy.
Topics: 3-Iodobenzylguanidine; Adrenergic Antagonists; Adult; Aged; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Female; Heart Ventricles; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Radionuclide Imaging; Radiopharmaceuticals; Sympathetic Nervous System; Technetium Tc 99m Sestamibi; Treatment Outcome; Ventricular Dysfunction, Left | 2003 |
Effects of carvedilol on oxidative stress in human endothelial cells and healthy volunteers.
Topics: Adrenergic Antagonists; Adult; Antioxidants; Carbazoles; Carvedilol; Cells, Cultured; Cross-Over Studies; Dinoprost; Dinoprostone; Double-Blind Method; Endothelial Cells; Humans; Isoprostanes; Lipoproteins, LDL; Male; Metoprolol; Oxidative Stress; Propanolamines; Reactive Nitrogen Species; Reactive Oxygen Species; Thiobarbituric Acid Reactive Substances; Tyrosine | 2004 |
A description of the clinical characteristics at baseline of patients recruited into the Carvedilol or Metoprolol European Trial (COMET).
Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Body Mass Index; Carbazoles; Carvedilol; Comorbidity; Double-Blind Method; Female; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Patient Selection; Propanolamines; Randomized Controlled Trials as Topic; Severity of Illness Index; Sex Factors | 2004 |
Carvedilol but not metoprolol reduces beta-adrenergic responsiveness after complete elimination from plasma in vivo.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Alleles; Allosteric Site; Binding Sites; Carbazoles; Cardiac Output; Carvedilol; Cross-Over Studies; Cytochrome P-450 CYP2D6; Dobutamine; Echocardiography, Stress; Genotype; Heart Atria; Heart Rate; Humans; Inactivation, Metabolic; Isoproterenol; Male; Metoprolol; Propanolamines; Protein Binding; Receptors, Adrenergic, beta; Up-Regulation | 2004 |
Adverse effects of beta-blocker therapy for patients with heart failure: a quantitative overview of randomized trials.
Topics: Adrenergic beta-Antagonists; Aged; Bisoprolol; Bradycardia; Carbazoles; Carvedilol; Dizziness; Fatigue; Female; Follow-Up Studies; Heart Conduction System; Heart Failure; Humans; Hypotension; Male; Metoprolol; Middle Aged; Propanolamines; Risk Factors; Risk Reduction Behavior; Severity of Illness Index; Statistics as Topic; Treatment Failure; Ventricular Dysfunction, Left; Withholding Treatment | 2004 |
[A randomized comparison of carvedilol and metoprolol in patients with chronic heart failure. The Carvedilol Or Metoprolol European Trial (COMET) ].
Topics: Adrenergic beta-Antagonists; Aged; Carbazoles; Carvedilol; Double-Blind Method; Female; Follow-Up Studies; Heart Failure; Humans; Male; Metoprolol; Propanolamines; Survival Rate | 2004 |
Beta-adrenergic blockade and myocardial perfusion in coronary artery disease: differential effects in stenotic versus remote myocardial segments.
Topics: Adrenergic beta-Antagonists; Ammonia; Carbazoles; Carbon Isotopes; Carvedilol; Coronary Artery Disease; Coronary Circulation; Coronary Stenosis; Coronary Vessels; Female; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Radionuclide Imaging; Radiopharmaceuticals; Treatment Outcome | 2004 |
Metabolic effects of carvedilol vs metoprolol in patients with type 2 diabetes mellitus and hypertension: a randomized controlled trial.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Glucose; Carbazoles; Carvedilol; Diabetes Mellitus, Type 2; Double-Blind Method; Glycated Hemoglobin; Humans; Hypertension; Metoprolol; Middle Aged; Propanolamines; Renin-Angiotensin System | 2004 |
Current concepts of pharmacotherapy in hypertension. Carvedilol: new considerations for its use in the diabetic patient with hypertension.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Glucose; Carbazoles; Carvedilol; Diabetes Mellitus, Type 2; Double-Blind Method; Humans; Hypertension; Metoprolol; Propanolamines | 2005 |
Carvedilol versus metoprolol in patients undergoing direct percutaneous coronary interventions for myocardial infarction: effects on QT dynamicity.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angioplasty, Balloon, Coronary; Carbazoles; Carvedilol; Combined Modality Therapy; Electrocardiography; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Propanolamines; Prospective Studies | 2005 |
Carvedilol versus metoprolol in the acute phase of myocardial infarction:.
Topics: Adrenergic beta-Antagonists; Angioplasty, Balloon, Coronary; Carbazoles; Carvedilol; Female; Heart Rate; Hemodynamics; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Propanolamines; Prospective Studies | 2005 |
Prognostic relevance of atrial fibrillation in patients with chronic heart failure on long-term treatment with beta-blockers: results from COMET.
Topics: Adrenergic beta-Antagonists; Aged; Atrial Fibrillation; Carbazoles; Carvedilol; Double-Blind Method; Electrocardiography; Female; Heart Failure; Humans; Long-Term Care; Male; Metoprolol; Middle Aged; Prognosis; Propanolamines; Ventricular Dysfunction, Left | 2005 |
Regression of carotid atherosclerosis by control of morning blood pressure peak in newly diagnosed hypertensive patients.
Topics: Adult; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Carbazoles; Carotid Artery Diseases; Carvedilol; Circadian Rhythm; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Propanolamines; Risk Factors; Treatment Outcome; Ultrasonography | 2005 |
Effects of different degrees of sympathetic antagonism on cytokine network in patients with ischemic dilated cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Echocardiography; Female; Heart Failure; Humans; Interleukin-1; Interleukin-6; Male; Metoprolol; Middle Aged; Myocardial Ischemia; Propanolamines; Stroke Volume; Tumor Necrosis Factor-alpha; Ventricular Remodeling | 2005 |
Effects of metoprolol and carvedilol on cause-specific mortality and morbidity in patients with chronic heart failure--COMET.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Death, Sudden, Cardiac; Double-Blind Method; Female; Heart Failure; Hospitalization; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Propanolamines; Survival Analysis | 2005 |
Symptoms in patients with heart failure are prognostic predictors: insights from COMET.
Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Carbazoles; Carvedilol; Disease Progression; Double-Blind Method; Dyspnea; Fatigue; Female; Follow-Up Studies; Forecasting; Heart Failure; Hospitalization; Humans; Male; Metoprolol; Middle Aged; Prognosis; Propanolamines; Severity of Illness Index; Survival Rate | 2005 |
Selective versus nonselective beta-adrenergic receptor blockade in chronic heart failure: differential effects on myocardial energy substrate utilization.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbazoles; Carvedilol; Double-Blind Method; Energy Metabolism; Fatty Acids, Nonesterified; Heart Failure; Humans; Lactates; Metoprolol; Middle Aged; Myocardium; Oxygen Consumption; Propanolamines; Sympathetic Nervous System | 2005 |
Drug and drug-device therapy in heart failure patients in the post-COMET and SCD-HeFT era.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme 2; Anti-Arrhythmia Agents; Carbazoles; Carvedilol; Death, Sudden, Cardiac; Defibrillators, Implantable; Heart Failure; Humans; Metoprolol; Peptidyl-Dipeptidase A; Propanolamines; Ventricular Dysfunction, Left | 2005 |
How should COMET influence heart failure practice?
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Double-Blind Method; Drug Administration Schedule; Heart Failure; Humans; Metoprolol; Propanolamines; Research Design | 2004 |
Comprehensive adrenergic receptor blockade with carvedilol is superior to beta-1-selective blockade with metoprolol in patients with heart failure: COMET.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Heart Failure; Humans; Metoprolol; Morbidity; Multicenter Studies as Topic; Propanolamines; Time Factors; Ventricular Dysfunction, Left | 2004 |
Influence of heart rate, blood pressure, and beta-blocker dose on outcome and the differences in outcome between carvedilol and metoprolol tartrate in patients with chronic heart failure: results from the COMET trial.
Topics: Adrenergic beta-Antagonists; Blood Pressure; Carbazoles; Carvedilol; Chronic Disease; Dose-Response Relationship, Drug; Double-Blind Method; Female; Heart Failure; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Treatment Outcome | 2005 |
Effects of beta-blockers on implantable cardioverter defibrillator therapy and survival in the patients with ischemic cardiomyopathy (from the Multicenter Automatic Defibrillator Implantation Trial-II).
Topics: Adrenergic beta-Antagonists; Aged; Atenolol; Carbazoles; Carvedilol; Defibrillators, Implantable; Female; Follow-Up Studies; Humans; Male; Metoprolol; Myocardial Ischemia; Propanolamines; Prospective Studies; Stroke Volume; Survival Rate; Tachycardia; Treatment Outcome | 2005 |
Carvedilol improves myocardial contractility compared with metoprolol in patients with chronic hibernating myocardium after revascularization.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Apoptosis; Carbazoles; Carvedilol; Chronic Disease; Coronary Artery Bypass; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Contraction; Myocardial Stunning; Propanolamines; Ventricular Function, Left | 2005 |
Early initiation of beta blockade in heart failure: issues and evidence.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Heart Failure; Humans; Hypertension; Metoprolol; Propanolamines; Ventricular Function; Ventricular Remodeling | 2005 |
[Antihypertensive activity and effect on parameters of heart rate variability of beta-blockers carvedilol and metoprolol].
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Female; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged; Propanolamines; Severity of Illness Index | 2005 |
Carvedilol exerts more potent antiadrenergic effect than metoprolol in heart failure.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Exercise Test; Female; Heart Failure; Heart Function Tests; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Natriuretic Peptide, Brain; Norepinephrine; Propanolamines | 2005 |
Comparison of carvedilol and metoprolol in patients with acute myocardial infarction undergoing primary coronary intervention--the PASSAT Study.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Angioplasty, Balloon, Coronary; Carbazoles; Carvedilol; Chemotherapy, Adjuvant; Clinical Trials as Topic; Comorbidity; Female; Germany; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Prognosis; Propanolamines; Treatment Outcome; Ventricular Dysfunction, Left | 2006 |
After myocardial infarction carvedilol improves insulin resistance compared to metoprolol.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; C-Peptide; Carbazoles; Carvedilol; Cholesterol, LDL; Female; Glucose Clamp Technique; Humans; Insulin Resistance; Male; Metoprolol; Middle Aged; Myocardial Infarction; Propanolamines; Triglycerides | 2006 |
A comparison of the effects of carvedilol and metoprolol on well-being, morbidity, and mortality (the "patient journey") in patients with heart failure: a report from the Carvedilol Or Metoprolol European Trial (COMET).
Topics: Adrenergic beta-Antagonists; Aged; Carbazoles; Cardiac Output, Low; Carvedilol; Chronic Disease; Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Female; Hospitalization; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Quality of Life; Severity of Illness Index; Treatment Outcome | 2006 |
Carvedilol versus Metoprolol for the prevention of atrial fibrillation after off-pump coronary bypass surgery: rationale and design of the Carvedilol or Metoprolol Post-Revascularization Atrial Fibrillation Controlled Trial (COMPACT).
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Atrial Fibrillation; Carbazoles; Carvedilol; Coronary Artery Bypass, Off-Pump; Female; Humans; Male; Metoprolol; Middle Aged; Propanolamines | 2006 |
Effect of amiodarone and sotalol on ventricular defibrillation threshold: the optimal pharmacological therapy in cardioverter defibrillator patients (OPTIC) trial.
Topics: Adrenergic beta-Antagonists; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Bisoprolol; Carbazoles; Carvedilol; Combined Modality Therapy; Defibrillators, Implantable; Female; Heart Arrest; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Propanolamines; Sotalol; Ventricular Fibrillation; Ventricular Function, Left | 2006 |
[Estimation of effectiveness of the prevention of sudden cardiac death in patients with myocardial infarction].
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Death, Sudden, Cardiac; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Propanolamines; Treatment Outcome | 2006 |
Effect of beta-blocker therapy on left atrial function in patients with heart failure: comparison of metoprolol succinate with carvedilol.
Topics: Adrenergic beta-Antagonists; Aged; Atrial Function, Left; Carbazoles; Carvedilol; Echocardiography, Doppler; Female; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Natriuretic Peptide, Brain; Peptide Fragments; Propanolamines; Severity of Illness Index; Treatment Outcome; Ventricular Function, Left | 2007 |
Effects of metoprolol and carvedilol on pre-existing and new onset diabetes in patients with chronic heart failure: data from the Carvedilol Or Metoprolol European Trial (COMET).
Topics: Adrenergic beta-Antagonists; Aged; Blood Glucose; Carbazoles; Carvedilol; Chi-Square Distribution; Diabetes Mellitus; Double-Blind Method; Europe; Female; Heart Failure; Humans; Incidence; Male; Metoprolol; Middle Aged; Prevalence; Propanolamines; Prospective Studies; Retrospective Studies | 2007 |
Carvedilol protects better against vascular events than metoprolol in heart failure: results from COMET.
Topics: Adrenergic beta-Antagonists; Angina, Unstable; Carbazoles; Carvedilol; Death, Sudden, Cardiac; Double-Blind Method; Female; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Propanolamines; Stroke; Survival Analysis; Treatment Outcome | 2007 |
[Effect of low doses of metoprolol, bisoprolol and carvedilol on mortality in patients with left ventricular dysfunction after acute myocardial infarction].
Topics: Acute Disease; Adrenergic beta-Antagonists; Adult; Aged; Angioplasty, Balloon, Coronary; Bisoprolol; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Propanolamines; Retrospective Studies; Stroke Volume; Treatment Outcome; Ventricular Dysfunction, Left | 2006 |
beta-blocker use and diabetes symptom score: results from the GEMINI study.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbazoles; Carvedilol; Cognition; Diabetes Mellitus, Type 2; Double-Blind Method; Fatigue; Female; Humans; Hyperglycemia; Hypertension; Hypoglycemia; Male; Metoprolol; Middle Aged; Nervous System Diseases; Pain; Propanolamines; Renin-Angiotensin System; Treatment Outcome | 2007 |
Differential effect of beta-blocker therapy on insulin resistance as a function of insulin sensitizer use: results from GEMINI.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Glucose; Carbazoles; Carvedilol; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Insulin Resistance; Male; Metformin; Metoprolol; Middle Aged; Propanolamines; Thiazolidinediones; Treatment Outcome | 2007 |
Comparison of the efficacy of metoprolol and carvedilol for preventing atrial fibrillation after coronary bypass surgery.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Atrial Fibrillation; Carbazoles; Carvedilol; Coronary Artery Bypass; Female; Humans; Male; Metoprolol; Middle Aged; Postoperative Complications; Preoperative Care; Propanolamines; Prospective Studies | 2008 |
Clinical reminders attached to echocardiography reports of patients with reduced left ventricular ejection fraction increase use of beta-blockers: a randomized trial.
Topics: Adrenergic beta-Antagonists; Aged; Carbazoles; Carvedilol; Echocardiography; Electronic Mail; Humans; Kartagener Syndrome; Male; Metoprolol; Middle Aged; Propanolamines; Ventricular Dysfunction, Left; Ventricular Function, Left | 2007 |
Association of beta-blocker dose with serum procollagen concentrations and cardiac response to spironolactone in patients with heart failure.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Carbazoles; Carvedilol; Diuretics; Dose-Response Relationship, Drug; Female; Fibrosis; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Peptide Fragments; Procollagen; Propanolamines; Prospective Studies; Radioimmunoassay; Spironolactone | 2007 |
Should beta-blocker therapy be reduced or withdrawn after an episode of decompensated heart failure? Results from COMET.
Topics: Adrenergic beta-Antagonists; Aged; Carbazoles; Carvedilol; Female; Heart Failure; Hospitalization; Humans; Male; Metoprolol; Middle Aged; Prognosis; Propanolamines; Withholding Treatment | 2007 |
Randomized active-controlled study comparing effects of treatment with carvedilol versus metoprolol in patients with left ventricular dysfunction after acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Cause of Death; Disease-Free Survival; Female; Follow-Up Studies; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Propanolamines; Quality of Life; Survival Rate; Ventricular Dysfunction, Left | 2007 |
Effects of carvedilol versus metoprolol on endothelial function and oxidative stress in patients with type 2 diabetes mellitus.
Topics: Aged; Antihypertensive Agents; Carbazoles; Carvedilol; Diabetes Mellitus, Type 2; Double-Blind Method; Endothelium, Vascular; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Oxidative Stress; Propanolamines | 2007 |
Body weight changes with beta-blocker use: results from GEMINI.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Body Weight; Carbazoles; Carvedilol; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Propanolamines; Prospective Studies | 2007 |
The safety of amiodarone in patients with heart failure.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Carbazoles; Carvedilol; Death, Sudden, Cardiac; Female; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Multivariate Analysis; Propanolamines | 2007 |
Effects of beta-blocker therapy on high sensitivity c-reactive protein, oxidative stress, and cardiac function in patients with congestive heart failure.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Biomarkers; C-Reactive Protein; Carbazoles; Carvedilol; Exercise Tolerance; Female; Heart Failure; Humans; Interleukin-6; Lipid Peroxidation; Male; Metoprolol; Middle Aged; Natriuretic Peptide, Brain; Oxidative Stress; Oxygen Consumption; Propanolamines; Radionuclide Ventriculography; Single-Blind Method | 2007 |
Carvedilol increases copper-zinc superoxide dismutase activity in patients with acute myocardial infarction.
Topics: Adrenergic Antagonists; Carbazoles; Carvedilol; Drug Therapy, Combination; Erythrocytes; Female; Free Radical Scavengers; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Propanolamines; Streptokinase; Superoxide Dismutase | 2007 |
[The effects of beta-adrenoblocker therapy on the physical working capacity of patients with chronic heart failure of various origin].
Topics: Activities of Daily Living; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbazoles; Carbon Dioxide; Cardiac Output, Low; Cardiomyopathy, Dilated; Carvedilol; Chronic Disease; Drug Administration Schedule; Exercise Test; Female; Heart Failure; Humans; Lung; Male; Metoprolol; Middle Aged; Myocardial Infarction; Propanolamines; Pulmonary Gas Exchange; Pulmonary Ventilation; Severity of Illness Index; Surveys and Questionnaires; Treatment Outcome | 2007 |
Prognostic importance of plasma NT-pro BNP in chronic heart failure in patients treated with a beta-blocker: results from the Carvedilol Or Metoprolol European Trial (COMET) trial.
Topics: Adrenergic beta-Antagonists; Aged; Carbazoles; Carvedilol; Chronic Disease; Female; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Natriuretic Peptide, Brain; Peptide Fragments; Prognosis; Propanolamines | 2007 |
Effect of carvedilol and metoprolol on the mode of death in patients with heart failure.
Topics: Adrenergic beta-Antagonists; Aged; Carbazoles; Carvedilol; Cause of Death; Chi-Square Distribution; Double-Blind Method; Female; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Proportional Hazards Models; Survival Analysis; Treatment Outcome | 2007 |
Optimal beta-blocker for prevention of atrial fibrillation after on-pump coronary artery bypass graft surgery: carvedilol versus metoprolol.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Aged; Atrial Fibrillation; Carbazoles; Carvedilol; Coronary Artery Bypass; Double-Blind Method; Female; Humans; Kaplan-Meier Estimate; Male; Metoprolol; Middle Aged; Postoperative Complications; Propanolamines; Prospective Studies; Time Factors | 2007 |
Lowering blood pressure with beta-blockers in combination with other renin-angiotensin system blockers in patients with hypertension and type 2 diabetes: results from the GEMINI Trial.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Carbazoles; Carvedilol; Diabetes Mellitus, Type 2; Diuretics; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Middle Aged; Propanolamines; Renin-Angiotensin System | 2007 |
Differential effects of carvedilol and metoprolol succinate on plasma norepinephrine release and peak exercise heart rate in subjects with chronic heart failure.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Chronic Disease; Dose-Response Relationship, Drug; Exercise Test; Female; Heart Failure; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Norepinephrine; Propanolamines; Prospective Studies | 2008 |
Comparison of the effects of carvedilol and metoprolol on exercise ventilatory efficiency in patients with congestive heart failure.
Topics: Adrenergic beta-Antagonists; Aged; Blood Pressure; Carbazoles; Carbon Dioxide; Carvedilol; Dose-Response Relationship, Drug; Exercise; Female; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Natriuretic Peptide, Brain; Oxygen Consumption; Prognosis; Propanolamines; Pulmonary Ventilation; Stroke Volume | 2008 |
[Effect of antihypertensive agents from various pharmacological groups on blood pressure reaction during stress-testing. Part I. Comparative characteristics of medications, exerting effect of sympathoadrenal block].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Blood Pressure; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electrocardiography; Exercise Test; Exercise Tolerance; Follow-Up Studies; Humans; Hypertension; Imidazoles; Metoprolol; Middle Aged; Propanolamines; Sympathetic Nervous System; Sympatholytics; Time Factors; Treatment Outcome | 2008 |
Comparison of carvedilol and metoprolol on serum lipid concentration in diabetic hypertensive patients.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Double-Blind Method; Female; Humans; Hypertension; Lipids; Male; Metoprolol; Propanolamines; Prospective Studies | 2009 |
Demographic analyses of the effects of carvedilol vs metoprolol on glycemic control and insulin sensitivity in patients with type 2 diabetes and hypertension in the Glycemic Effects in Diabetes Mellitus: Carvedilol-Metoprolol Comparison in Hypertensives (
Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Aged, 80 and over; Blood Glucose; Blood Pressure; Carbazoles; Carvedilol; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Glycated Hemoglobin; Humans; Hypertension; Insulin Resistance; Male; Metoprolol; Middle Aged; Prevalence; Propanolamines; Racial Groups; Risk Factors; Sex Factors; Treatment Outcome; United States | 2008 |
Years-needed-to-treat to add 1 year of life: a new metric to estimate treatment effects in randomized trials.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Confidence Intervals; Follow-Up Studies; Heart Failure; Humans; Kaplan-Meier Estimate; Life Expectancy; Metoprolol; Odds Ratio; Propanolamines; Survival Rate; Time Factors; Treatment Outcome | 2009 |
A pilot study on the role of autoantibody targeting the beta1-adrenergic receptor in the response to beta-blocker therapy for congestive heart failure.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; Autoantibodies; Carbazoles; Carvedilol; Diastole; Enzyme-Linked Immunosorbent Assay; Female; Heart Failure; Heart Rate; Heart Ventricles; Humans; Male; Metoprolol; Middle Aged; Natriuretic Peptide, Brain; Norepinephrine; Pilot Projects; Propanolamines; Radiography; Receptors, Adrenergic, beta-1; Stroke Volume; Systole | 2009 |
Beta-receptor selectivity of carvedilol and metoprolol succinate in patients with heart failure (SELECT trial): a randomized dose-ranging trial.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Blood Glucose; Carbazoles; Carvedilol; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Interactions; Female; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Potassium; Propanolamines; Terbutaline | 2009 |
Effect of carvedilol on coronary flow reserve in patients with hypertensive left-ventricular hypertrophy.
Topics: Administration, Sublingual; Adrenergic beta-Antagonists; Aged; Blood Flow Velocity; Blood Pressure; Brachial Artery; Carbazoles; Carvedilol; Coronary Circulation; Diastole; Dipyridamole; Echocardiography, Transesophageal; Endothelin-1; Endothelium, Vascular; Female; Heart Rate; Humans; Hypertension; Hypertrophy, Left Ventricular; Injections, Intravenous; Male; Metoprolol; Middle Aged; Nitroglycerin; Propanolamines; Vasodilation; Vasodilator Agents | 2010 |
Differences between beta-blockers in patients with chronic heart failure and chronic obstructive pulmonary disease: a randomized crossover trial.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Bisoprolol; Carbazoles; Carvedilol; Chronic Disease; Cross-Over Studies; Echocardiography; Female; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Natriuretic Peptide, Brain; Propanolamines; Pulmonary Disease, Chronic Obstructive; Pulse; Respiratory Function Tests; Walking | 2010 |
Metoprolol compared to carvedilol deteriorates insulin-stimulated endothelial function in patients with type 2 diabetes - a randomized study.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Denmark; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Forearm; Humans; Hypoglycemic Agents; Infusions, Intra-Arterial; Insulin; Insulin Resistance; Male; Metoprolol; Middle Aged; Nitroprusside; Photoplethysmography; Propanolamines; Regional Blood Flow; Serotonin; Time Factors; Treatment Outcome; Vasodilation; Vasodilator Agents | 2010 |
Effects of cAMP and β-adrenergic receptor antagonists on the function of peripheral T helper lymphocytes in patients with heart failure.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Carbazoles; Carvedilol; Cell Separation; Cyclic AMP; Female; Flow Cytometry; Heart Failure; Humans; Interferon-gamma; Interleukin-10; Male; Metoprolol; Middle Aged; Propanolamines; Radioimmunoassay; T-Lymphocytes, Helper-Inducer | 2011 |
[Effects of carvedilol and metoprolol on expression of autoantibodies against cardiac adrenergic receptors in aged patients with chronic heart failure and ventricular arrhythmia].
Topics: Aged; Aged, 80 and over; Arrhythmias, Cardiac; Autoantibodies; Carbazoles; Carvedilol; Female; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Receptors, Adrenergic | 2010 |
β-blockade restores muscle sympathetic rhythmicity in human heart failure.
Topics: Adrenergic beta-1 Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Carbazoles; Carvedilol; Drug Therapy, Combination; Female; Heart Failure; Heart Rate; Humans; Linear Models; Male; Metoprolol; Middle Aged; Muscle, Skeletal; Ontario; Periodicity; Peroneal Nerve; Propanolamines; Signal Processing, Computer-Assisted; Stroke Volume; Sympathetic Nervous System; Time Factors; Treatment Outcome; Ventricular Function | 2011 |
[Effect of carvedilol and metoprolol R administered with or without atorvastatin on elastic properties of vascular wall and parameters of inflammation in patients with chronic heart failure of ischemic origin].
Topics: Adrenergic beta-1 Receptor Antagonists; Adult; Aged; Anticholesteremic Agents; Arterioles; Atorvastatin; Blood Pressure; C-Reactive Protein; Carbazoles; Carvedilol; Chronic Disease; Drug Therapy, Combination; Elasticity; Female; Heart Failure; Heptanoic Acids; Humans; Interleukin-6; Male; Metoprolol; Middle Aged; Myocardial Ischemia; Propanolamines; Pyrroles; Stroke Volume; Treatment Outcome; Tumor Necrosis Factor-alpha; Vascular Resistance | 2011 |
Endothelial function is unaffected by changing between carvedilol and metoprolol in patients with heart failure--a randomized study.
Topics: Aged; Aged, 80 and over; Carbazoles; Carvedilol; Drug Substitution; Endothelium, Vascular; Female; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Vasodilation | 2011 |
Carvedilol compared with metoprolol on left ventricular ejection fraction after coronary artery bypass graft.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Carbazoles; Carvedilol; Coronary Artery Bypass; Double-Blind Method; Female; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Prospective Studies; Stroke Volume | 2011 |
The impact of carvedilol and metoprolol on serum lipid concentrations and symptoms in patients with hyperthyroidism.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Carbazoles; Carvedilol; Heart Rate; Humans; Hypertension; Hyperthyroidism; Lipids; Metoprolol; Middle Aged; Propanolamines; Thyrotropin; Thyroxine | 2012 |
β-AR polymorphisms and glycemic and lipid parameters in hypertensive individuals receiving carvedilol or metoprolol.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Blood Glucose; Carbazoles; Carvedilol; Female; Humans; Insulin; Male; Metoprolol; Middle Aged; Polymorphism, Single Nucleotide; Propanolamines; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Triglycerides | 2012 |
Effect of β-blocker cessation on chronotropic incompetence and exercise tolerance in patients with advanced heart failure.
Topics: Adrenergic beta-Antagonists; Adult; Analysis of Variance; Biomarkers; Bisoprolol; Carbazoles; Carvedilol; Drug Administration Schedule; Exercise Test; Exercise Tolerance; Female; Heart Failure; Heart Rate; Humans; Male; Metoprolol; Middle Aged; New York City; Norepinephrine; Oxygen Consumption; Propanolamines; Prospective Studies; Respiration; Time Factors | 2012 |
Metoprolol vs. carvedilol or carvedilol plus N-acetyl cysteine on post-operative atrial fibrillation: a randomized, double-blind, placebo-controlled study.
Topics: Acetylcysteine; Adult; Aged; Analysis of Variance; Anti-Arrhythmia Agents; Atrial Fibrillation; Carbazoles; Carvedilol; Coronary Artery Bypass; Double-Blind Method; Drug Therapy, Combination; Humans; Length of Stay; Metoprolol; Middle Aged; Postoperative Complications; Propanolamines; Treatment Outcome; Young Adult | 2013 |
Effect of metoprolol versus carvedilol on outcomes in MADIT-CRT (multicenter automatic defibrillator implantation trial with cardiac resynchronization therapy).
Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Analysis of Variance; Carbazoles; Cardiac Resynchronization Therapy; Carvedilol; Combined Modality Therapy; Defibrillators, Implantable; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Heart Failure; Humans; Kaplan-Meier Estimate; Male; Metoprolol; Middle Aged; Multivariate Analysis; Prognosis; Propanolamines; Proportional Hazards Models; Prospective Studies; Risk Assessment; Severity of Illness Index; Stroke Volume; Survival Analysis; Treatment Outcome | 2013 |
Impact of carvedilol and metoprolol on inappropriate implantable cardioverter-defibrillator therapy: the MADIT-CRT trial (Multicenter Automatic Defibrillator Implantation With Cardiac Resynchronization Therapy).
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; Aged; Atrial Fibrillation; Carbazoles; Cardiac Resynchronization Therapy; Carvedilol; Combined Modality Therapy; Defibrillators, Implantable; Female; Heart Failure; Humans; Male; Metoprolol; Multivariate Analysis; Propanolamines; Regression Analysis | 2013 |
Differential effects of nonselective versus selective β-blockers on cardiac sympathetic activity and hemostasis in patients with heart failure.
Topics: 3-Iodobenzylguanidine; Adrenergic beta-Antagonists; Aged; Carbazoles; Carvedilol; Female; Haplotypes; Heart; Heart Failure; Hemostasis; Humans; Male; Metoprolol; Middle Aged; Patient Selection; Propanolamines; Radionuclide Imaging; Receptors, Adrenergic, beta-2; Sympathetic Nervous System; Treatment Outcome | 2013 |
The effect of low-dose carvedilol, nebivolol, and metoprolol on central arterial pressure and its determinants: a randomized clinical trial.
Topics: Adolescent; Adrenergic beta-1 Receptor Antagonists; Adult; Aged; Arterial Pressure; Benzopyrans; Carbazoles; Carvedilol; Ethanolamines; Female; Heart Rate; Humans; Hypertension; Male; Manometry; Metoprolol; Middle Aged; Nebivolol; Propanolamines; Prospective Studies; Treatment Outcome; Young Adult | 2013 |
Calcium channel blockers improve exercise capacity and reduce N-terminal Pro-B-type natriuretic peptide levels compared with beta-blockers in patients with permanent atrial fibrillation.
Topics: Adrenergic beta-Antagonists; Aged; Atrial Fibrillation; Calcium Channel Blockers; Carbazoles; Carvedilol; Cross-Over Studies; Delayed-Action Preparations; Diltiazem; Exercise Tolerance; Female; Humans; Male; Metoprolol; Natriuretic Peptide, Brain; Oxygen Consumption; Peptide Fragments; Propanolamines; Prospective Studies; Verapamil | 2014 |
Evaluation of beta-blockers on left ventricular dyssynchrony and reverse remodeling in idiopathic dilated cardiomyopathy: A randomized trial of carvedilol and metoprolol.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Aged; Biomarkers; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Double-Blind Method; Female; Humans; Male; Metoprolol; Middle Aged; Natriuretic Peptide, Brain; Peptide Fragments; Propanolamines; Prospective Studies; Recovery of Function; Stroke Volume; Time Factors; Treatment Outcome; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling | 2014 |
Oxidative status, inflammation, and postoperative atrial fibrillation with metoprolol vs carvedilol or carvedilol plus N-acetyl cysteine treatment.
Topics: Acetylcysteine; Aged; Antihypertensive Agents; Atrial Fibrillation; Carbazoles; Cardiac Surgical Procedures; Carvedilol; Double-Blind Method; Drug Therapy, Combination; Female; Free Radical Scavengers; Humans; Inflammation; Leukocyte Count; Male; Metoprolol; Middle Aged; Oxidative Stress; Postoperative Period; Propanolamines; Prospective Studies; Treatment Outcome | 2014 |
Addition of N-acetyl cysteine to carvedilol decreases the incidence of acute renal injury after cardiac surgery.
Topics: Acetylcysteine; Acute Kidney Injury; Adrenergic beta-1 Receptor Antagonists; Aged; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Carbazoles; Cardiac Surgical Procedures; Carvedilol; Creatinine; Double-Blind Method; Female; Humans; Incidence; Male; Metoprolol; Middle Aged; Propanolamines; Prospective Studies; Time Factors; Treatment Outcome; Turkey | 2014 |
Improved rate control reduces cardiac troponin T levels in permanent atrial fibrillation.
Topics: Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Biomarkers; Carbazoles; Carvedilol; Cross-Over Studies; Diltiazem; Down-Regulation; Female; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Norway; Propanolamines; Prospective Studies; Time Factors; Treatment Outcome; Troponin T; Verapamil | 2014 |
Rate-control drugs affect variability and irregularity measures of RR intervals in patients with permanent atrial fibrillation.
Topics: Adrenergic beta-1 Receptor Antagonists; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Calcium Channel Blockers; Carbazoles; Carvedilol; Cross-Over Studies; Diltiazem; Electrocardiography, Ambulatory; Female; Heart Conduction System; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Norway; Propanolamines; Time Factors; Treatment Outcome; Verapamil | 2015 |
Effect of Combining Ivabradine and β-Blockers: Focus on the Use of Carvedilol in the SHIFT Population.
Topics: Adrenergic beta-Antagonists; Aged; Benzazepines; Bisoprolol; Carbazoles; Cardiovascular Agents; Carvedilol; Double-Blind Method; Drug Therapy, Combination; Female; Heart Failure, Systolic; Hospitalization; Humans; Ivabradine; Male; Metoprolol; Middle Aged; Nebivolol; Propanolamines; Proportional Hazards Models; Treatment Outcome | 2015 |
Carvedilol Compared With Metoprolol Succinate in the Treatment and Prognosis of Patients With Stable Chronic Heart Failure: Carvedilol or Metoprolol Evaluation Study.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-1 Receptor Antagonists; Aged; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; Female; Germany; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Prognosis; Propanolamines; Propensity Score; Prospective Studies; Survival Rate; Treatment Outcome | 2015 |
Comparison of the effects of metoprolol or carvedilol on serum gamma-glutamyltransferase and uric acid levels among patients with acute coronary syndrome without ST segment elevation.
Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Aged; Carbazoles; Carvedilol; Female; gamma-Glutamyltransferase; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Prospective Studies; Treatment Outcome; Uric Acid | 2016 |
Impact of Carvedilol versus β1-selective β blockers (bisoprolol, metoprolol, and nebivolol) in patients with acute myocardial infarction undergoing percutaneous coronary intervention.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-1 Receptor Antagonists; Bisoprolol; Carbazoles; Carvedilol; Electrocardiography; Female; Follow-Up Studies; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Nebivolol; Percutaneous Coronary Intervention; Preoperative Care; Propanolamines; Prospective Studies; Registries; Republic of Korea; Retrospective Studies; Survival Rate; Treatment Outcome | 2015 |
Troponin I levels in permanent atrial fibrillation-impact of rate control and exercise testing.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Biomarkers; Calcium Channel Blockers; Carbazoles; Carvedilol; Cross-Over Studies; Diltiazem; Down-Regulation; Exercise Test; Female; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Norway; Predictive Value of Tests; Propanolamines; Treatment Outcome; Troponin I; Troponin T; Verapamil | 2016 |
Relationship between heart failure, concurrent chronic obstructive pulmonary disease and beta-blocker use: a Danish nationwide cohort study.
Topics: Adrenergic beta-1 Receptor Agonists; Aged; Bisoprolol; Carvedilol; Cause of Death; Comorbidity; Denmark; Drug Therapy, Combination; Female; Follow-Up Studies; Heart Failure; Humans; Male; Metoprolol; Nebivolol; Pulmonary Disease, Chronic Obstructive; Registries; Retrospective Studies; Time Factors; Treatment Outcome | 2018 |
237 other study(ies) available for carvedilol and metoprolol
| Article | Year |
|---|---|
Binding of arylpiperazines, (aryloxy)propanolamines, and tetrahydropyridylindoles to the 5-HT1A receptor: contribution of the molecular lipophilicity potential to three-dimensional quantitative structure-affinity relationship models.
Topics: Indoles; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Piperazines; Propanolamines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Structure-Activity Relationship; Tetrahydronaphthalenes | 1996 |
Potent and selective human beta(3)-adrenergic receptor antagonists.
Topics: Adipocytes; Adrenergic beta-Antagonists; Aminophenols; Animals; Binding, Competitive; CHO Cells; Cloning, Molecular; Cricetinae; Cyclic AMP; Humans; Ligands; Lipolysis; Macaca mulatta; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3; Structure-Activity Relationship; Sulfonamides | 1999 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Interaction of digoxin with antihypertensive drugs via MDR1.
Topics: Animals; Antihypertensive Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cells, Cultured; Digoxin; Drug Interactions; Humans; Time Factors | 2002 |
The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors.
Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Algorithms; Animals; Cell Line; CHO Cells; Cricetinae; Dioxoles; Humans; Propanolamines; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3 | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
High-throughput log P determination by ultraperformance liquid chromatography: a convenient tool for medicinal chemists.
Topics: Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Chromatography, Liquid; Mathematics; Pharmaceutical Preparations; Software | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Lipophilicity of basic drugs measured by hydrophilic interaction chromatography.
Topics: Chemistry, Pharmaceutical; Chromatography; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Pharmaceutical Preparations; Solubility; Technology, Pharmaceutical | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Novel carvedilol analogues that suppress store-overload-induced Ca2+ release.
Topics: Carbazoles; Carvedilol; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Molecular Structure; Propanolamines; Ryanodine Receptor Calcium Release Channel; Structure-Activity Relationship | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Drug repurposing and rediscovery: Design, synthesis and preliminary biological evaluation of 1-arylamino-3-aryloxypropan-2-ols as anti-melanoma agents.
Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Discovery; Drug Repositioning; Drug Screening Assays, Antitumor; Humans; Melanoma; Molecular Docking Simulation; Molecular Structure; Propanols; Skin Neoplasms; Structure-Activity Relationship; Tumor Cells, Cultured | 2020 |
Receptor pharmacology of carvedilol in the human heart.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Binding, Competitive; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Cyclic AMP; Guanylyl Imidodiphosphate; Humans; Iodocyanopindolol; Metoprolol; Myocardium; Pindolol; Propanolamines; Propranolol; Receptors, Adrenergic, beta; Vasodilator Agents | 1992 |
Effects of norepinephrine on the oxidative pentose phosphate pathway in the rat heart.
Topics: Adrenergic beta-Antagonists; Animals; Blotting, Northern; Carbazoles; Carvedilol; Female; Glucosephosphate Dehydrogenase; Heart; Heart Rate; In Vitro Techniques; Metoprolol; Myocardium; Norepinephrine; Nucleic Acid Hybridization; Pentose Phosphate Pathway; Propanolamines; Rats; Rats, Inbred Strains; RNA | 1992 |
[Regression of myocardial hypertrophy in hypertensives on chronic beta-receptor block].
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Carbazoles; Cardiomegaly; Carvedilol; Chronic Disease; Drug Evaluation; Echocardiography; Female; Gallopamil; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged; Physical Exertion; Propanolamines; Rest; Time Factors | 1986 |
Acute effects of catecholamines on function of the rat right heart.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Carbazoles; Carvedilol; Catecholamines; Female; Heart Rate; Isoproterenol; Metoprolol; Norepinephrine; Prazosin; Propanolamines; Rats; Rats, Sprague-Dawley; Ventricular Function, Right | 1993 |
[Carvedilol--2 companies introduce the same antihypertensive agent].
Topics: Antihypertensive Agents; Carbazoles; Carvedilol; Drug Industry; Humans; Metoprolol; Norway; Propanolamines | 1994 |
[Carvedilol--2 companies introduce the same antihypertensive agent].
Topics: Antihypertensive Agents; Carbazoles; Carvedilol; Drug Costs; Drug Industry; Humans; Metoprolol; Norway; Propanolamines | 1994 |
Carvedilol and its metabolites suppress endothelin-1 production in human endothelial cell culture.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Ascorbic Acid; Calcium Channel Blockers; Carbazoles; Carvedilol; Cells, Cultured; Endothelin-1; Endothelium, Vascular; Humans; Metoprolol; Nicardipine; Prazosin; Probucol; Propanolamines; Propranolol; Umbilical Veins | 1997 |
Effects of beta blockers on symptoms and functional capacity in heart failure.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Exercise Tolerance; Heart Failure; Hospitalization; Humans; Metoprolol; Morbidity; Propanolamines; Randomized Controlled Trials as Topic | 1997 |
Comparison of metoprolol and carvedilol pharmacology and cardioprotection in rabbit ischemia and reperfusion model.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Antioxidants; Blood Pressure; Carbazoles; Carvedilol; Heart Rate; Male; Metoprolol; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Oxidation-Reduction; Peroxidase; Propanolamines; Propranolol; Rabbits; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Recombinant Proteins; Solubility; Ventricular Function, Left; Ventricular Pressure | 1998 |
Comparative effects of carvedilol and metoprolol on cardiac ischemia-reperfusion injury.
Topics: Adrenergic beta-Antagonists; Animals; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; L-Lactate Dehydrogenase; Metoprolol; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Propanolamines; Rabbits; Ventricular Function, Left | 1998 |
Effect of beta-blockers on free radical-induced cardiac contractile dysfunction.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Calcium; Calcium-Transporting ATPases; Carbazoles; Carvedilol; Electric Stimulation; Female; Humans; Hydroxyl Radical; In Vitro Techniques; Male; Metoprolol; Middle Aged; Myocardial Contraction; Propanolamines; Receptors, Adrenergic, beta; Sarcoplasmic Reticulum | 1999 |
Effect of selective versus nonselective beta blockade on QT dispersion in patients with nonischemic dilated cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Death, Sudden, Cardiac; Electrocardiography; Female; Heart Conduction System; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Retrospective Studies; Stroke Volume; Treatment Outcome | 1999 |
[The effect of carvedilol on contrast echocardiography in comparison to metoprolol in conscious dogs].
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Carbazoles; Carvedilol; Contrast Media; Coronary Circulation; Dogs; Echocardiography; Heart; Heart Rate; Image Processing, Computer-Assisted; Metoprolol; Phosphatidylcholines; Propanolamines | 1999 |
[The role of beta-adrenergic blocking agents in treatment of heart failure].
Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Heart Failure; Humans; Metoprolol; Propanolamines | 1999 |
[New milestones in the therapy of chronic heart failure with beta blockers].
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Bisoprolol; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Controlled Clinical Trials as Topic; Double-Blind Method; Heart Failure; Humans; Metoprolol; Placebos; Prognosis; Propanolamines; Quality of Life; Randomized Controlled Trials as Topic | 2000 |
Disparate effects of carvedilol versus metoprolol treatment of stroke-prone spontaneously hypertensive rats on endothelial function of resistance arteries.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Carbazoles; Carvedilol; Endothelium, Vascular; Humans; Hypertension; Male; Mesenteric Arteries; Metoprolol; Propanolamines; Rats; Rats, Inbred SHR; Stroke; Vascular Resistance; Vasodilation | 2000 |
Beta-blockers for heart failure.
Topics: Adrenergic beta-Antagonists; Bisoprolol; Bradycardia; Carbazoles; Carvedilol; Heart Failure; Humans; Hypotension; Metoprolol; Propanolamines | 2000 |
Different intrinsic activities of bucindolol, carvedilol and metoprolol in human failing myocardium.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Carbazoles; Carvedilol; Catecholamines; Female; Guanylyl Imidodiphosphate; Heart Failure; Humans; In Vitro Techniques; Iodocyanopindolol; Male; Metoprolol; Middle Aged; Myocardial Contraction; Propanolamines | 2000 |
Effect of carvedilol in comparison with metoprolol on myocardial collagen postinfarction.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Carbazoles; Carvedilol; Collagen; Heart Rate; Heart Ventricles; Hydroxyproline; Male; Metoprolol; Myocardial Infarction; Organ Size; Propanolamines; Rats; Rats, Sprague-Dawley; Treatment Outcome; Ventricular Remodeling | 2000 |
Beta-blockade in adriamycin-induced cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antineoplastic Agents; Carbazoles; Cardiomyopathies; Cardiomyopathy, Dilated; Carvedilol; Doxorubicin; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Contraction; Neoplasms; Propanolamines; Propranolol; Retrospective Studies; Stroke Volume | 2000 |
Are there differences between vasodilating and nonvasodilating beta-blockers in patients with heart failure? Do patients with ischemic heart disease benefit to the same degree?
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Female; Heart Failure; Hospitalization; Humans; Male; Meta-Analysis as Topic; Metoprolol; Myocardial Ischemia; Propanolamines; Reproducibility of Results; Vasodilator Agents | 2000 |
Are all beta-blockers for heart failure the same?
Topics: Adrenergic beta-Antagonists; Antioxidants; Carbazoles; Cardiac Output, Low; Carvedilol; Humans; Metoprolol; Propanolamines; Randomized Controlled Trials as Topic | 2000 |
A comparison of carvedilol and metoprolol antioxidant activities in vitro.
Topics: Adrenergic beta-Antagonists; Animals; Antioxidants; Carbazoles; Carvedilol; Cell Membrane; Cells, Cultured; Free Radicals; Heart; Lipid Peroxidation; Metoprolol; Neurons; Oxidative Stress; Propanolamines; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances | 2000 |
[Beta blockers: the end of controversy].
Topics: Adrenergic beta-Antagonists; Carbazoles; Cardiac Output, Low; Carvedilol; Cause of Death; Clinical Trials as Topic; Female; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Survival Rate | 2000 |
Selective or nonselective beta-adrenergic blockade in patients with congestive heart failure.
Topics: Adrenergic beta-Antagonists; Animals; Carbazoles; Carvedilol; Heart Failure; Hemodynamics; Humans; Metoprolol; Prognosis; Propanolamines; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Vasoconstriction | 2000 |
[Beta-blockers in the treatment of chronic heart failure. How should results of clinical studies be introduced into clinical practice].
Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Heart Failure; Humans; Metoprolol; Propanolamines | 2000 |
Differential effects of carvedilol and metoprolol on isoprenaline-induced changes in beta-adrenoceptor density and systolic function in rat cardiac myocytes.
Topics: Adrenergic beta-Antagonists; Analysis of Variance; Animals; Carbazoles; Carvedilol; Cell Size; Cells, Cultured; Electric Stimulation; Guanylyl Imidodiphosphate; Isoproterenol; Male; Metoprolol; Microscopy, Phase-Contrast; Myocardium; Propanolamines; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Regression Analysis | 2001 |
Extracellular matrix proteins in cardiac fibroblasts derived from rat hearts with chronic pressure overload: effects of beta-receptor blockade.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Blotting, Western; Carbazoles; Carvedilol; Cell Division; Cells, Cultured; Extracellular Matrix Proteins; Fibroblasts; Fluorescent Antibody Technique, Indirect; Heart Ventricles; Hemodynamics; Hypertrophy, Left Ventricular; Interferon-gamma; Male; Metoprolol; Myocardium; Prazosin; Propanolamines; Rats; Rats, Wistar; Ventricular Pressure | 2001 |
[Cardiac insufficiency and B-blockers].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbazoles; Carvedilol; Female; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Propanolamines | 1998 |
Beta-blockade in chronic heart failure.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Heart Failure; Humans; Metoprolol; Oxygen Consumption; Predictive Value of Tests; Prognosis; Propanolamines; Stroke Volume; Treatment Outcome | 2001 |
Nebivolol, carvedilol and metoprolol do not influence cardiac Ca(2+) sensitivity.
Topics: Adrenergic beta-Antagonists; Benzopyrans; Calcium; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; Ethanolamines; Female; Heart Ventricles; Humans; In Vitro Techniques; Male; Metoprolol; Middle Aged; Myocardial Contraction; Nebivolol; Propanolamines; Ventricular Function | 2001 |
Nebivolol, bucindolol, metoprolol and carvedilol are devoid of intrinsic sympathomimetic activity in human myocardium.
Topics: Adrenergic beta-Antagonists; Benzopyrans; Binding, Competitive; Bisoprolol; Carbazoles; Carvedilol; Ethanolamines; Female; Guanylyl Imidodiphosphate; Heart Ventricles; Humans; Imidazoles; In Vitro Techniques; Inhibitory Concentration 50; Isoproterenol; Male; Metoprolol; Middle Aged; Myocardial Contraction; Myocardium; Nebivolol; Propanolamines; Substrate Specificity; Sympathetic Nervous System; Sympathomimetics; Thermodynamics | 2001 |
Cost-effectiveness of beta-blocker therapy with metoprolol or with carvedilol for treatment of heart failure in Canada.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Canada; Carbazoles; Carvedilol; Cost-Benefit Analysis; Diuretics; Drug Therapy, Combination; Female; Furosemide; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Propanolamines | 2001 |
Beta-blockers in chronic heart failure.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Heart Failure; Humans; Metoprolol; Propanolamines | 2002 |
Different effects of carvedilol, metoprolol, and propranolol on left ventricular remodeling after coronary stenosis or after permanent coronary occlusion in rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Ascorbic Acid; Carbazoles; Cardiac Catheterization; Carvedilol; Coronary Disease; Coronary Stenosis; Disease Models, Animal; Dose-Response Relationship, Drug; Echocardiography; Hemodynamics; Male; Metoprolol; Norepinephrine; Propanolamines; Propranolol; Quinazolines; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Stroke Volume; Survival Rate; Thiobarbituric Acid Reactive Substances; Ventricular Function, Left; Ventricular Remodeling | 2002 |
Reimbursement claims analysis of outcomes with carvedilol and metoprolol.
Topics: Adrenergic beta-Antagonists; Carbazoles; Cardiac Output, Low; Carvedilol; Comorbidity; Fees, Pharmaceutical; Female; Health Services; Hospitalization; Humans; Insurance, Health; Logistic Models; Male; Metoprolol; Middle Aged; Propanolamines; Retrospective Studies | 2002 |
Unique effects of carvedilol on noradrenaline release in the human heart.
Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; Heart; Heart Failure; Humans; Metoprolol; Myocardium; Norepinephrine; Propanolamines; Treatment Outcome | 2002 |
Novel use of a short-acting intravenous beta blocker in combination with inotropic therapy as a bridge to chronic oral beta blockade in patients with advanced heart failure.
Topics: Adrenergic beta-Antagonists; Carbazoles; Cardiotonic Agents; Carvedilol; Drug Therapy, Combination; Heart Failure; Humans; Infusions, Intravenous; Metoprolol; Milrinone; Propanolamines; Treatment Outcome | 2002 |
Intermediate effects of treatment with metoprolol or carvedilol in children with left ventricular systolic dysfunction.
Topics: Adolescent; Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Child; Child, Preschool; Echocardiography, Doppler; Female; Humans; Infant; Male; Metoprolol; Propanolamines; Systole; Treatment Outcome; Ventricular Dysfunction, Left | 2002 |
Current research on carvedilol in heart failure.
Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Heart Failure; Humans; Metoprolol; Propanolamines | 2002 |
Carvedilol increases the production of interleukin-12 and interferon-gamma and improves the survival of mice infected with the encephalomyocarditis virus.
Topics: Adrenergic beta-Antagonists; Animals; Carbazoles; Cardiovirus Infections; Carvedilol; Dose-Response Relationship, Drug; Encephalomyocarditis virus; Interferon-gamma; Interleukin-12; Male; Metoprolol; Mice; Mice, Inbred DBA; Myocarditis; Propanolamines; Propranolol; Survival Rate | 2003 |
Treatment of chronic heart failure with beta adrenergic blockade beyond controlled clinical trials: the BRING-UP experience.
Topics: Adrenergic beta-Antagonists; Aged; Bisoprolol; Carbazoles; Cardiac Output, Low; Carvedilol; Chronic Disease; Contraindications; Female; Follow-Up Studies; Humans; Male; Metoprolol; Middle Aged; Multivariate Analysis; Professional Practice; Propanolamines; Treatment Outcome | 2003 |
Marked improvement in left ventricular ejection fraction during long-term beta-blockade in patients with chronic heart failure: clinical correlates and prognostic significance.
Topics: Adrenergic beta-Antagonists; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Female; Follow-Up Studies; Heart Failure; Heart Function Tests; Humans; Male; Metoprolol; Middle Aged; Multivariate Analysis; Odds Ratio; Prognosis; Propanolamines; Stroke Volume; Ventricular Dysfunction, Left; Ventricular Function, Left | 2003 |
QT dispersion after beta-blocker therapy (carvedilol or metoprolol) in children with heart failure.
Topics: Adolescent; Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Child; Child Welfare; Child, Preschool; Electrocardiography; Heart Failure; Humans; Infant; Infant Welfare; Long QT Syndrome; Metoprolol; Propanolamines; Retrospective Studies; Stroke Volume; Treatment Outcome; Ventricular Dysfunction, Left | 2003 |
Beta blockers in heart failure.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Clinical Trials as Topic; Heart Failure; Humans; Metoprolol; Propanolamines | 2003 |
[The changes of plasma levels of brain natriuretic peptides in evaluation of treatment responses in chronic heart failure].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Atrial Natriuretic Factor; Carbazoles; Carvedilol; Female; Heart Failure; Humans; Immunoradiometric Assay; Male; Metoprolol; Middle Aged; Natriuretic Peptide, Brain; Propanolamines; Radioimmunoassay | 2003 |
[Comparative effects of carvedilol and metoprolol in preventing from left ventricular remodeling after acute myocardial infarction in rats].
Topics: Adrenergic beta-Antagonists; Animals; Carbazoles; Carvedilol; Female; Metoprolol; Myocardial Infarction; Propanolamines; Rats; Rats, Sprague-Dawley; Ventricular Remodeling | 2001 |
Clinical trials update from the European Society of Cardiology Heart Failure meeting: COMET, COMPANION, Tezosentan and SHAPE.
Topics: Adrenergic beta-Antagonists; Carbazoles; Cardiac Pacing, Artificial; Carvedilol; Defibrillators, Implantable; Endpoint Determination; Health Education; Heart Failure; Hemodynamics; Humans; Metoprolol; Propanolamines; Pyridines; Randomized Controlled Trials as Topic; Tetrazoles; Treatment Outcome; Vasodilator Agents | 2003 |
Comparison of effectiveness of carvedilol versus metoprolol or atenolol for atrial fibrillation appearing after coronary artery bypass grafting or cardiac valve operation.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Atenolol; Atrial Fibrillation; Carbazoles; Carvedilol; Coronary Artery Bypass; Coronary Artery Disease; Female; Heart Valve Diseases; Heart Valve Prosthesis Implantation; Humans; Male; Metoprolol; Middle Aged; Outcome Assessment, Health Care; Postoperative Complications; Propanolamines; Retrospective Studies; Vasodilator Agents | 2003 |
Decreased heart rate recovery after exercise in patients with congestive heart failure: effect of beta-blocker therapy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Carbazoles; Carvedilol; Diastole; Exercise; Exercise Test; Female; Heart Failure; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Oxygen Consumption; Predictive Value of Tests; Propanolamines; Recovery of Function; Stroke Volume; Systole; Time Factors; Treatment Outcome | 2003 |
COMET: a proposed mechanism of action to explain the results and concerns about dose.
Topics: Adenosine Triphosphatases; Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Carbazoles; Carvedilol; Cation Transport Proteins; Clinical Trials as Topic; Death, Sudden, Cardiac; Dose-Response Relationship, Drug; Heart Failure; Humans; Hypokalemia; Metoprolol; Potassium; Propanolamines | 2003 |
COMET: a proposed mechanism of action to explain the results and concerns about dose.
Topics: Adrenergic alpha-Antagonists; Adrenergic Antagonists; Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Heart Failure; Heart Rate; Humans; Metoprolol; Propanolamines; Research Design; Treatment Outcome | 2003 |
[Comet or snoop?].
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Europe; Heart Failure; Humans; Metoprolol; Multicenter Studies as Topic; Propanolamines; Randomized Controlled Trials as Topic | 2003 |
[The COMET study compares effect of two different beta-blockers in chronic heart failure. Carvedilol better than metoprolol].
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Chronic Disease; Heart Failure; Humans; Metoprolol; Propanolamines; Randomized Controlled Trials as Topic; Treatment Outcome | 2003 |
[Effect of beta-blockers metoprolol CR/XL and carvedilol on left ventricular contractility in patients with chronic low cardiac output].
Topics: Adrenergic beta-Antagonists; Carbazoles; Cardiac Output, Low; Carvedilol; Chronic Disease; Drug Administration Schedule; Female; Gated Blood-Pool Imaging; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Ventricular Function, Left | 2003 |
Top heart failure drugs compared.
Topics: Adrenergic beta-Antagonists; Carbazoles; Cardiac Output, Low; Carvedilol; Heart Failure; Humans; Metoprolol; Prescription Fees; Propanolamines | 2003 |
[For the first time beta blockers are in direct comparison With carvedilol weak hearts beat longer].
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Double-Blind Method; Follow-Up Studies; Heart Failure; Humans; Metoprolol; Multicenter Studies as Topic; Propanolamines; Randomized Controlled Trials as Topic; Time Factors | 2003 |
[Comparative study in heart failure. Which beta blocker saves more life time?].
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Clinical Trials as Topic; Heart Failure; Humans; Metoprolol; Propanolamines; Risk; Time Factors | 2003 |
AVID and COMET.
Topics: Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Carbazoles; Carvedilol; Heart Conduction System; Heart Failure; Humans; Hypolipidemic Agents; Metoprolol; Propanolamines | 2003 |
[A fairer comparison between carvedilol and metoprolol is still to be done].
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; Heart Failure; Heart Rate; Humans; Metoprolol; Propanolamines; Randomized Controlled Trials as Topic | 2003 |
A COMET lost.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Controlled Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Heart Failure; Humans; Male; Metoprolol; Prognosis; Propanolamines; Severity of Illness Index; Survival Analysis; Systole; Treatment Outcome | 2003 |
[Is "COMET" pointing in the right direction?--Pro].
Topics: Adrenergic beta-Antagonists; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Dose-Response Relationship, Drug; Heart Rate; Humans; Metoprolol; Propanolamines; Treatment Outcome | 2003 |
[Is "COMET" pointing in the right direction?--Con].
Topics: Adrenergic beta-Antagonists; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Dose-Response Relationship, Drug; Humans; Metoprolol; Propanolamines; Survival Analysis; Treatment Outcome | 2003 |
Has COMET solved the controversy as to whether carvedilol is better than metoprolol in heart failure?
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Female; Heart Failure; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Randomized Controlled Trials as Topic; Treatment Outcome | 2004 |
Cardioprotective effects of carvedilol on acute autoimmune myocarditis: anti-inflammatory effects associated with antioxidant property.
Topics: Acute Disease; Adrenergic beta-Antagonists; Animals; Anti-Inflammatory Agents; Antioxidants; Autoimmune Diseases; Blood Pressure; Body Weight; Carbazoles; Cardiotonic Agents; Carvedilol; Heart Rate; Metoprolol; Myocarditis; Myocardium; Nuclease Protection Assays; Organ Size; Propanolamines; Propranolol; Rats; Ribonucleases; Thiobarbituric Acid Reactive Substances | 2004 |
In heart failure, all beta-blockers are not necessarily equal.
Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Clinical Trials as Topic; Cost-Benefit Analysis; Female; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Propanolamines | 2003 |
Patterns of beta-blocker utilization in patients with chronic heart failure: experience from a specialized outpatient heart failure clinic.
Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Ambulatory Care Facilities; Carbazoles; Carvedilol; Chronic Disease; Cross-Sectional Studies; Drug Utilization Review; Female; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Respiratory Function Tests; Retrospective Studies; Sex Factors | 2004 |
[Beta-blocking drugs indicated in patients with heart failure].
Topics: Adrenergic beta-Antagonists; Blood Pressure; Carbazoles; Carvedilol; Heart Diseases; Heart Failure; Heart Rate; Humans; Metoprolol; Propanolamines; Treatment Outcome | 2003 |
Inhibitory effects of carvedilol on calcium channels in vascular smooth muscle cells.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Aorta; Calcium; Calcium Channels; Calcium Signaling; Carbazoles; Carvedilol; Cell Division; Endothelin-1; Metoprolol; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Propanolamines; Rats; Vasodilator Agents; Vasopressins | 2003 |
Comparison of metoprolol with low, middle and high doses of carvedilol in prevention of postinfarction left ventricular remodeling in rats.
Topics: Animals; Carbazoles; Cardiac Volume; Carvedilol; Dose-Response Relationship, Drug; Female; Heart Rate; Metoprolol; Myocardial Infarction; Propanolamines; Random Allocation; Rats; Rats, Sprague-Dawley; Ventricular Function, Left; Ventricular Pressure; Ventricular Remodeling | 2003 |
Case studies in heart failure.
Topics: Activities of Daily Living; Adrenergic beta-Antagonists; Adult; Aged; Carbazoles; Cardiac Catheterization; Cardiotonic Agents; Carvedilol; Diet, Sodium-Restricted; Dyspnea; Echocardiography; Electrocardiography; Fatigue; Female; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Milrinone; Phosphodiesterase Inhibitors; Prognosis; Propanolamines; Treatment Outcome; Vasodilator Agents; Ventricular Function, Left | 2003 |
[Beta blocker in heart failure. Dosage too low].
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Clinical Trials as Topic; Dose-Response Relationship, Drug; Heart Failure; Humans; Metoprolol; Propanolamines; Survival Rate | 2003 |
Which beta-blocker for heart failure?
Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Contraindications; Coronary Disease; Evidence-Based Medicine; Heart Failure; Humans; Hypertension; Male; Metoprolol; Middle Aged; Propanolamines; Randomized Controlled Trials as Topic | 2004 |
A comment on COMET: how to interpret a positive trial?
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; Europe; Heart Failure; Humans; Metoprolol; Multicenter Studies as Topic; Propanolamines; Randomized Controlled Trials as Topic; Receptors, Adrenergic, beta-1; Sympathetic Nervous System; Ventricular Dysfunction, Left | 2003 |
Beta-blockers for heart failure.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Heart Failure; Humans; Metoprolol; Propanolamines | 2003 |
Partial reversal of cachexia by beta-adrenergic receptor blocker therapy in patients with chronic heart failure.
Topics: Adrenergic beta-Antagonists; Biomarkers; Blood Pressure; Body Weight; Cachexia; Carbazoles; Carvedilol; Chronic Disease; Female; Heart Failure; Heart Rate; Humans; Insulin; Leptin; Male; Metoprolol; Middle Aged; Norepinephrine; Propanolamines; Prospective Studies; Severity of Illness Index; Stroke Volume; Treatment Outcome | 2003 |
The effect of beta-blocker on hamster model BIO 53.58 with dilated cardiomyopathy determined using 123I-MIBG myocardial scintigraphy.
Topics: 3-Iodobenzylguanidine; Adrenergic beta-Antagonists; Animals; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Metoprolol; Propanolamines; Radionuclide Imaging; Radiopharmaceuticals; Severity of Illness Index; Treatment Outcome | 2003 |
The European Society of Cardiology working group on heart failure: Heart Failure Update 2003.
Topics: Carbazoles; Cardiac Pacing, Artificial; Carvedilol; Eplerenone; Europe; Heart Failure; Humans; Metoprolol; Myocardial Infarction; Prognosis; Propanolamines; Spironolactone; Tumor Necrosis Factor-alpha; Uric Acid | 2003 |
[Therapy of chronic heart failure--carvedilol vs. metoprolol. COMET Study].
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Cause of Death; Chronic Disease; Double-Blind Method; Europe; Heart Failure; Humans; Metoprolol; Multicenter Studies as Topic; Propanolamines; Randomized Controlled Trials as Topic; Survival Rate | 2004 |
Cardioprotective effects of carvedilol on acute autoimmune myocarditis.
Topics: Administration, Oral; Animals; Autoimmune Diseases; Carbazoles; Cardiotonic Agents; Carvedilol; Dose-Response Relationship, Drug; Metoprolol; Myocarditis; Myocardium; Myosins; Propanolamines; Propranolol; Proteins; Rats; Rats, Inbred Lew; Thiobarbituric Acid Reactive Substances | 2004 |
Hemodynamic characterization of left ventricular function in experimental coxsackieviral myocarditis: effects of carvedilol and metoprolol.
Topics: Animals; Carbazoles; Carvedilol; Coxsackievirus Infections; Male; Metoprolol; Mice; Mice, Inbred BALB C; Myocarditis; Propanolamines; Ventricular Function, Left | 2004 |
Commentary on the Carvedilol or Metoprolol European Trial (COMET).
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Heart Failure; Humans; Metoprolol; Propanolamines; Randomized Controlled Trials as Topic; Treatment Outcome | 2004 |
Carvedilol and metoprolol European trial: do the results merit challenge?
Topics: Adrenergic beta-Antagonists; Aged; Carbazoles; Carvedilol; Double-Blind Method; Heart Failure; Humans; Metoprolol; Middle Aged; Propanolamines; Randomized Controlled Trials as Topic; Research Design; Survival Rate | 2004 |
Do pharmacological differences among beta-blockers affect their clinical efficacy in heart failure?
Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Heart Failure; Humans; Metoprolol; Propanolamines; Randomized Controlled Trials as Topic; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2 | 2004 |
Brain natriuretic peptide response is heterogeneous during beta-blocker therapy for congestive heart failure.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Biomarkers; Blood Pressure; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Myocardial Contraction; Natriuretic Peptide, Brain; Propanolamines; Stroke Volume; Time Factors; Treatment Outcome; Ventricular Function, Left | 2004 |
[Correction of baroreflex sensitivity impairment and efficacy of prevention of sudden arrhythmic death in patients with postinfarction left ventricular dysfunction].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Amiodarone; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Antihypertensive Agents; Arrhythmias, Cardiac; Atenolol; Baroreflex; Bisoprolol; Carbazoles; Carvedilol; Data Interpretation, Statistical; Death, Sudden, Cardiac; Drug Therapy, Combination; Echocardiography; Electrocardiography; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Perindopril; Phenylephrine; Propanolamines; Time Factors; Ventricular Dysfunction, Left | 2004 |
Estimating mortality reduction by comparing survival curves.
Topics: Carbazoles; Cardiovascular Agents; Carvedilol; Computer Simulation; Evidence-Based Medicine; Heart Failure; Humans; Metoprolol; Propanolamines; Proportional Hazards Models; Randomized Controlled Trials as Topic; Survival Analysis; Survival Rate; Time Factors | 2004 |
Death and hospitalization in heart failure patients receiving carvedilol vs. metoprolol tartrate.
Topics: Adrenergic beta-Antagonists; Aged; Carbazoles; Carvedilol; Female; Heart Failure; Hospitalization; Humans; Male; Metoprolol; Propanolamines; Retrospective Studies; Risk Factors | 2005 |
Carvedilol, metoprolol, and insulin resistance.
Topics: Antihypertensive Agents; Carbazoles; Carvedilol; Diabetes Mellitus, Type 2; Humans; Hypertension; Insulin Resistance; Metoprolol; Propanolamines | 2005 |
Long-term effects of carvedilol or metoprolol on left ventricular function in ischemic and nonischemic cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Ischemia; Propanolamines; Prospective Studies; Time Factors; Ultrasonography; Ventricular Function, Left | 2005 |
Carvedilol improves left ventricular function in murine coxsackievirus-induced acute myocarditis association with reduced myocardial interleukin-1beta and MMP-8 expression and a modulated immune response.
Topics: Adrenergic beta-Antagonists; Animals; Carbazoles; Carvedilol; Coxsackievirus Infections; Interleukin-1; Male; Matrix Metalloproteinase 8; Matrix Metalloproteinases; Metoprolol; Mice; Mice, Inbred BALB C; Myocarditis; Propanolamines; RNA, Messenger; Tissue Inhibitor of Metalloproteinases; Ventricular Function, Left | 2005 |
Exchange of beta-blockers in heart failure patients. Experiences from the poststudy phase of COMET (the Carvedilol or Metoprolol European Trial).
Topics: Adrenergic beta-Antagonists; Aged; Blood Pressure; Carbazoles; Carvedilol; Female; Heart Failure; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Randomized Controlled Trials as Topic; Treatment Outcome | 2005 |
Effect of beta-blocker therapy on myocardial perfusion defects in thallium-201 scintigraphy in patients with dilated cardiomyopathy.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Coronary Circulation; Echocardiography; Female; Hemodynamics; Humans; Male; Metoprolol; Middle Aged; Natriuretic Peptides; Propanolamines; Radionuclide Imaging; Radiopharmaceuticals; Thallium Radioisotopes; Ventricular Function, Left | 2005 |
Effects of beta-blocker therapy on ventilatory responses to exercise in patients with heart failure.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Exercise Test; Exercise Tolerance; Female; Follow-Up Studies; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Pulmonary Ventilation; Quality of Life; Respiratory Function Tests; Retrospective Studies; Treatment Outcome; Ventricular Function, Left | 2005 |
Do metoprolol and carvedilol have equivalent effects on diurnal heart rate in patients with chronic heart failure?
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Electrocardiography, Ambulatory; Heart Failure; Heart Rate; Humans; Metoprolol; Propanolamines; Randomized Controlled Trials as Topic; Stroke Volume | 2005 |
Practical recommendations for the use of ACE inhibitors, beta-blockers, aldosterone antagonists and angiotensin receptor blockers in heart failure: putting guidelines into practice.
Topics: Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Benzopyrans; Biphenyl Compounds; Bisoprolol; Captopril; Carbazoles; Carvedilol; Drug Therapy, Combination; Enalapril; Ethanolamines; Evidence-Based Medicine; Guideline Adherence; Heart Failure; Humans; Indoles; Lisinopril; Metoprolol; Mineralocorticoid Receptor Antagonists; Nebivolol; Practice Guidelines as Topic; Propanolamines; Ramipril; Spironolactone; Stroke Volume; Tetrazoles; Valine; Valsartan | 2005 |
Vagal heart rate responses to chronic beta-blockade in human heart failure relate to cardiac norepinephrine spillover.
Topics: Adrenergic beta-Antagonists; Baroreflex; Carbazoles; Carvedilol; Heart Failure; Heart Rate; Humans; Metoprolol; Middle Aged; Norepinephrine; Propanolamines; Vagus Nerve | 2005 |
Adherence and perception of medication in patients with chronic heart failure during a five-year randomised trial.
Topics: Activities of Daily Living; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Analysis of Variance; Carbazoles; Carvedilol; Chi-Square Distribution; Chronic Disease; Female; Follow-Up Studies; Health Knowledge, Attitudes, Practice; Health Status; Heart Failure; Humans; Male; Metoprolol; Multicenter Studies as Topic; Patient Compliance; Patient Education as Topic; Propanolamines; Randomized Controlled Trials as Topic; Severity of Illness Index; Stroke Volume; Surveys and Questionnaires; Sweden; Time Factors | 2006 |
Effect of beta-blockers on cardiac function and calcium handling protein in postinfarction heart failure rats.
Topics: Adrenergic beta-Antagonists; Animals; Calcium-Binding Proteins; Calcium-Transporting ATPases; Carbazoles; Carrier Proteins; Carvedilol; Heart Failure; Heart Ventricles; Male; Metoprolol; Models, Animal; Myocardial Contraction; Myocardial Infarction; Myocytes, Cardiac; Propanolamines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling | 2005 |
Carvedilol blocks beta2- more than beta1-adrenoceptors in human heart.
Topics: Adrenergic beta-Antagonists; Calcium Channels, L-Type; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; Epinephrine; Heart Atria; Heart Failure; Heart Ventricles; Humans; Imidazoles; In Vitro Techniques; Metoprolol; Myocardial Contraction; Myocardium; Norepinephrine; Patch-Clamp Techniques; Propanolamines; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2 | 2006 |
Differential effects of beta-blockers on albuminuria in patients with type 2 diabetes.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Albuminuria; Blood Pressure; Carbazoles; Carvedilol; Creatinine; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Humans; Male; Metoprolol; Middle Aged; Multivariate Analysis; Propanolamines; Randomized Controlled Trials as Topic | 2005 |
Comparison of HERG channel blocking effects of various beta-blockers-- implication for clinical strategy.
Topics: Adrenergic beta-Antagonists; Binding Sites; Carbazoles; Cardiovascular Diseases; Carvedilol; Cell Line; Dose-Response Relationship, Drug; Ether-A-Go-Go Potassium Channels; Humans; Long QT Syndrome; Membrane Potentials; Metoprolol; Mutation; Potassium Channel Blockers; Propanolamines; Propranolol; Protein Binding; Transfection | 2006 |
The effect of beta-blocker use on cyclosporine level in cardiac transplant recipients.
Topics: Absorption; Adrenergic beta-Antagonists; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carbazoles; Carvedilol; Cyclosporine; Drug Interactions; Heart Transplantation; Humans; Hypertension; Immunosuppressive Agents; Metoprolol; Propanolamines; Retrospective Studies | 2005 |
Carvedilol inhibits mitochondrial oxygen consumption and superoxide production during calcium overload in isolated heart mitochondria.
Topics: Adrenergic beta-Antagonists; Animals; Calcium; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; Heart Failure; In Vitro Techniques; Male; Metoprolol; Mitochondria, Heart; Oxygen Consumption; Propanolamines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Adrenergic, beta; Superoxides | 2006 |
[Use of betablockers in elderly patients with congestive heart failure].
Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Aged, 80 and over; Antihypertensive Agents; Bisoprolol; Carbazoles; Carvedilol; Data Interpretation, Statistical; Female; Heart Failure; Humans; Male; Metoprolol; Propanolamines; Risk Factors; Survival Analysis; Time Factors; Treatment Outcome; Vasodilator Agents | 2006 |
Pharmacokinetic and pharmacodynamic characteristics of beta-blockers: when differences may matter.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Delayed-Action Preparations; Heart Failure; Humans; Metoprolol; Propanolamines | 2006 |
The effects of combined versus selective adrenergic blockade on left ventricular and systemic hemodynamics, myocardial substrate preference, and regional perfusion in conscious dogs with dilated cardiomyopathy.
Topics: Adrenergic Antagonists; Adrenergic beta-Agonists; Animals; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Dogs; Heart Rate; Hemodynamics; Isoproterenol; Metoprolol; Myocardium; Propanolamines; Regional Blood Flow; Ventricular Function, Left | 2006 |
Carvedilol-induced antagonism of angiotensin II: a matter of alpha1-adrenoceptor blockade.
Topics: Adolescent; Adrenergic Antagonists; Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Carbazoles; Carvedilol; Coronary Vessels; Female; Humans; Inositol Phosphates; Irbesartan; Luciferases; Male; Metoprolol; Middle Aged; Myography; Propanolamines; Signal Transduction; Tetrazoles | 2006 |
Differential associations of beta-blockers with hemorrhagic events for chronic heart failure patients on warfarin.
Topics: Adrenergic beta-Antagonists; Adverse Drug Reaction Reporting Systems; Aged; Anticoagulants; Atenolol; Carbazoles; Carvedilol; Chi-Square Distribution; Chronic Disease; Drug Therapy, Combination; Drug Utilization; Female; Heart Failure; Hemorrhage; Hospitalization; Humans; Male; Metoprolol; Middle Aged; Pharmacoepidemiology; Practice Patterns, Physicians'; Propanolamines; Proportional Hazards Models; Risk Factors; Time Factors; United States; United States Department of Veterans Affairs; Warfarin | 2006 |
Simultaneous determination of ten antiarrhythic drugs and a metabolite in human plasma by liquid chromatography--tandem mass spectrometry.
Topics: Amiodarone; Anti-Arrhythmia Agents; Atenolol; Bisoprolol; Carbazoles; Carvedilol; Chromatography, Liquid; Diltiazem; Humans; Metoprolol; Mexiletine; Molecular Structure; Propanolamines; Propranolol; Reproducibility of Results; Sotalol; Tandem Mass Spectrometry; Verapamil | 2007 |
Does beta-blocker treatment influence central sleep apnoea?
Topics: Adrenergic beta-Antagonists; Carbazoles; Cardiac Output, Low; Cardiomyopathy, Dilated; Carvedilol; Chronic Disease; Female; Humans; Long-Term Care; Male; Metoprolol; Middle Aged; Propanolamines; Sleep Apnea Syndromes; Treatment Outcome | 2007 |
Effect of beta blockers (carvedilol or metoprolol XL) in patients with transposition of great arteries and dysfunction of the systemic right ventricle.
Topics: Adrenergic beta-Antagonists; Adult; Carbazoles; Carvedilol; Female; Follow-Up Studies; Humans; Male; Metoprolol; Propanolamines; Retrospective Studies; Stroke Volume; Transposition of Great Vessels; Treatment Outcome; Ultrasonography; Ventricular Dysfunction, Right | 2007 |
[Study of carvedilol on plaque stability in carotid atherosclerotic rabbits transfected by p53 gene].
Topics: Animal Feed; Animals; Apoptosis; Carbazoles; Carotid Artery Diseases; Carvedilol; Genes, p53; Humans; Male; Metoprolol; Oxidative Stress; Propanolamines; Rabbits; Transfection; Tumor Suppressor Protein p53 | 2007 |
Chronic treatment with carvedilol improves Ca(2+)-dependent ATP consumption in triton X-skinned fiber preparations of human myocardium.
Topics: Adrenergic beta-Antagonists; Calcium; Carbazoles; Carvedilol; Heart; Heart Failure; Humans; Metoprolol; Middle Aged; Myocardial Contraction; Myofibrils; Myosins; Octoxynol; Phosphorylation; Propanolamines; Troponin I | 2007 |
Effect of beta-blockers on beta3-adrenoceptor expression in chronic heart failure.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Carbazoles; Carvedilol; Chronic Disease; Gene Expression; Heart Failure; Heart Rate; Male; Metoprolol; Propanolamines; Rats; Rats, Wistar; Receptors, Adrenergic, beta-3; RNA, Messenger; Vasodilator Agents; Ventricular Function, Left; Ventricular Pressure; Ventricular Remodeling | 2007 |
Tolerability of beta-blockers in outpatients with refractory heart failure who were receiving continuous milrinone.
Topics: Adrenergic beta-Antagonists; Aged; Arrhythmias, Cardiac; Blood Pressure; Carbazoles; Cardiac Output, Low; Cardiotonic Agents; Carvedilol; Creatinine; Diuretics; Drug Therapy, Combination; Female; Heart Rate; Hospitals, University; Humans; Hypotension; Male; Metoprolol; Middle Aged; Milrinone; Oxygen Consumption; Propanolamines; Retrospective Studies; Sodium; Vasodilator Agents | 2007 |
Rational pharmacoeconomics?
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Drug Costs; Economics, Pharmaceutical; Humans; Insurance, Pharmaceutical Services; Metoprolol; New Zealand; Propanolamines | 2007 |
Comparative effectiveness of beta-adrenergic antagonists (atenolol, metoprolol tartrate, carvedilol) on the risk of rehospitalization in adults with heart failure.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Aluminum; Atenolol; California; Carbazoles; Carvedilol; Confidence Intervals; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Patient Readmission; Propanolamines; Proportional Hazards Models; Retrospective Studies; Risk Factors; Tartrates; Time Factors; Treatment Outcome | 2007 |
[Beta-adrenoceptor antagonists and ACE-inhibitors. Carvedilol compared with metoprolol as combination partner in cases of diabetes and hypertension].
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Carbazoles; Carvedilol; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Drug Therapy, Combination; Humans; Hypertension; Metoprolol; Propanolamines | 2007 |
Protective effects of carvedilol in murine model with the coxsackievirus B3-induced viral myocarditis.
Topics: Acute Disease; Adrenergic beta-Antagonists; Animals; Anti-Inflammatory Agents; Antioxidants; Carbazoles; Cardiotonic Agents; Carvedilol; Coxsackievirus Infections; Disease Models, Animal; Enterovirus B, Human; Interleukins; Male; Malondialdehyde; Metoprolol; Mice; Mice, Inbred BALB C; Myocarditis; Propanolamines; Quinazolines; Superoxide Dismutase; Up-Regulation | 2008 |
Beta blockers for the prevention of atrial fibrillation after coronary artery bypass surgery: carvedilol versus metoprolol.
Topics: Adrenergic beta-Antagonists; Atrial Fibrillation; Carbazoles; Carvedilol; Coronary Artery Bypass; Humans; Metoprolol; Postoperative Complications; Propanolamines; Randomized Controlled Trials as Topic | 2009 |
Carvedilol is more effective than metoprolol in preventing atrial fibrillation (AF) after coronary artery bypass.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Aged; Atrial Fibrillation; Carbazoles; Carvedilol; Coronary Artery Bypass; Female; Humans; Male; Metoprolol; Middle Aged; Postoperative Complications; Propanolamines; Time Factors | 2008 |
Carvedilol versus controlled-release metoprolol for elderly veterans with heart failure.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Carbazoles; Carvedilol; Cohort Studies; Delayed-Action Preparations; Female; Heart Failure; Hospitalization; Humans; Logistic Models; Male; Metoprolol; Practice Patterns, Physicians'; Propanolamines; Proportional Hazards Models; Retrospective Studies; Survival Rate; United States; Veterans | 2008 |
Comparison of pharmacodynamics between carvedilol and metoprolol in rats with isoproterenol-induced cardiac hypertrophy: effects of carvedilol enantiomers.
Topics: Adenylyl Cyclases; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Carbazoles; Cardiomegaly; Carvedilol; Cyclic AMP; Disease Models, Animal; Heart Failure; Heart Rate; Isoproterenol; Male; Metoprolol; Myocardium; Propanolamines; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Time Factors; Ventricular Function, Left | 2008 |
Intracellular mechanisms of specific beta-adrenoceptor antagonists involved in improved cardiac function and survival in a genetic model of heart failure.
Topics: Adrenergic beta-Antagonists; Animals; Carbazoles; Carvedilol; Disease Models, Animal; Heart Failure; Heart Function Tests; Hemodynamics; Intracellular Fluid; Male; Metoprolol; Mice; Mice, Congenic; Mice, Inbred C57BL; Mice, Knockout; Myocardial Contraction; Propanolamines; Random Allocation; Receptors, Adrenergic, beta | 2008 |
Lack of association between adrenergic receptor genotypes and survival in heart failure patients treated with carvedilol or metoprolol.
Topics: Adrenergic beta-Antagonists; Aged; Carbazoles; Carvedilol; Disease Progression; Female; Genotype; Haplotypes; Heart Failure; Humans; Kaplan-Meier Estimate; Male; Metoprolol; Middle Aged; Multivariate Analysis; Polymorphism, Single Nucleotide; Propanolamines; Receptors, Adrenergic; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2 | 2008 |
Efficacy of carvedilol for ischemia/reperfusion-induced oxidative renal injury in rats.
Topics: Animals; Antihypertensive Agents; Carbazoles; Carvedilol; Creatinine; Kidney; Kidney Function Tests; Male; Metoprolol; Nephrectomy; Propanolamines; Rats; Rats, Sprague-Dawley; Renal Circulation; Reperfusion Injury | 2008 |
Dosing of beta-blocker therapy before, during, and after hospitalization for heart failure (from Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure).
Topics: Adrenergic beta-Antagonists; Aged; Carbazoles; Carvedilol; Diastole; Drug Administration Schedule; Female; Heart Failure; Hospitalization; Humans; Male; Metoprolol; Propanolamines; Prospective Studies; Registries; Stroke Volume; Systole; Time Factors; Ventricular Function, Left | 2008 |
The beta2 adrenergic receptor Gln27Glu polymorphism affects insulin resistance in patients with heart failure: possible modulation by choice of beta blocker.
Topics: Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Blood Glucose; Carbazoles; Carvedilol; Codon; Fasting; Female; Genotype; Heart Failure; Humans; Insulin; Insulin Resistance; Male; Metoprolol; Middle Aged; Phenotype; Pilot Projects; Polymorphism, Genetic; Propanolamines; Prospective Studies; Receptors, Adrenergic, beta-2 | 2008 |
[Effects of carvedilol and metoprolol on cardiac fibrosis in rats with experimental myocardial infarction].
Topics: Adrenergic beta-Antagonists; Animals; Carbazoles; Carvedilol; Collagen; Disease Models, Animal; Fibrosis; Hydroxyproline; Male; Metoprolol; Myocardial Infarction; Myocardium; Propanolamines; Rats; Rats, Sprague-Dawley | 2008 |
Association between mortality and persistent use of beta blockers and angiotensin-converting enzyme inhibitors in patients with left ventricular systolic dysfunction and coronary artery disease.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Bisoprolol; Carbazoles; Carvedilol; Comorbidity; Coronary Artery Disease; Female; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Survival Analysis; Ventricular Dysfunction, Left | 2009 |
Therapeutic effect of {beta}-adrenoceptor blockers using a mouse model of dilated cardiomyopathy with a troponin mutation.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Disease Models, Animal; Electrocardiography; Metoprolol; Mice; Mutation; Propanolamines; Troponin T; Ventricular Function, Left | 2009 |
Molecular determinants of local anesthetic action of beta-blocking drugs: Implications for therapeutic management of long QT syndrome variant 3.
Topics: Adrenergic beta-Antagonists; Anesthetics, Local; Carbazoles; Carvedilol; Cell Line; Electrophysiology; Heart; Humans; Long QT Syndrome; Metoprolol; Propanolamines; Propranolol; Sodium Channels | 2010 |
Found in translation: metoprolol improves survival more than carvedilol in a mouse model of inherited dilated cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Animals; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Disease Models, Animal; Electrocardiography; Metoprolol; Mice; Propanolamines; Troponin T | 2009 |
Interaction of beta-blockers with the renal uptake transporter OCT2.
Topics: Adrenergic beta-Antagonists; Biological Transport; Bisoprolol; Carbazoles; Carvedilol; Cell Line; Humans; Kidney; Metformin; Metoprolol; Organic Cation Transport Proteins; Organic Cation Transporter 2; Propanolamines; Propranolol | 2009 |
Effects of carvedilol or metoprolol on PAI-1, tPA-mass concentration or Von Willebrand factor in chronic heart failure--a COMET substudy.
Topics: Adrenergic beta-Antagonists; Aged; Carbazoles; Carvedilol; Female; Heart Failure; Humans; Male; Metoprolol; Plasminogen Activator Inhibitor 1; Propanolamines; Randomized Controlled Trials as Topic; Sample Size; Sweden; Time Factors; Tissue Plasminogen Activator; Treatment Outcome; von Willebrand Factor | 2010 |
The effectiveness of collaborative medicine reviews in delaying time to next hospitalization for patients with heart failure in the practice setting: results of a cohort study.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Australia; Bisoprolol; Carbazoles; Carvedilol; Community Pharmacy Services; Cooperative Behavior; Databases as Topic; Family Practice; Female; Heart Failure; Hospitalization; House Calls; Humans; Kaplan-Meier Estimate; Male; Metoprolol; Program Evaluation; Propanolamines; Proportional Hazards Models; Referral and Consultation; Retrospective Studies; Risk Assessment; Time Factors; Treatment Outcome; Veterans; Widowhood | 2009 |
Carvedilol treatment ameliorates acute coxsackievirus B3-induced myocarditis associated with oxidative stress reduction.
Topics: Adrenergic Antagonists; Aldehydes; Animals; Body Weight; Carbazoles; Carvedilol; Electrocardiography; Enterovirus; Glutathione Peroxidase; Heart; Hemodynamics; Male; Malondialdehyde; Metoprolol; Mice; Mice, Inbred BALB C; Myocarditis; Myocardium; Organ Size; Oxidative Stress; Propanolamines; Superoxide Dismutase; Survival Rate; Time Factors; Viral Load | 2010 |
Differential effects of carvedilol and metoprolol on renal function in patients with heart failure.
Topics: Adrenergic beta-1 Receptor Antagonists; Aged; Carbazoles; Carvedilol; Drug Evaluation; Female; Glomerular Filtration Rate; Heart Failure; Humans; Kidney; Kidney Diseases; Kidney Function Tests; Male; Metoprolol; Middle Aged; Propanolamines; Retrospective Studies; Stroke Volume | 2010 |
Which beta-blocker is most effective in heart failure?
Topics: Adrenergic beta-Antagonists; Animals; Benzopyrans; Bisoprolol; Carbazoles; Carvedilol; Clinical Trials as Topic; Comorbidity; Diabetes Mellitus; Disease Progression; Ethanolamines; Heart Failure; Humans; Lung Diseases, Obstructive; Metoprolol; Myocardial Infarction; Nebivolol; Propanolamines; Treatment Outcome; Ventricular Dysfunction, Left; Ventricular Remodeling | 2010 |
Relation of ADRB1, CYP2D6, and UGT1A1 polymorphisms with dose of, and response to, carvedilol or metoprolol therapy in patients with chronic heart failure.
Topics: Adrenergic beta-Antagonists; Aged; Alleles; Carbazoles; Carvedilol; Chronic Disease; Comorbidity; Cytochrome P-450 CYP2D6; Genotype; Glucuronosyltransferase; Haplotypes; Heart Failure; Humans; Linear Models; Metoprolol; Middle Aged; Phenotype; Polymerase Chain Reaction; Polymorphism, Genetic; Propanolamines; Receptors, Adrenergic, beta-1; Treatment Outcome | 2010 |
Association of physical training with beta-blockers in heart failure in mice.
Topics: Adrenergic beta-Antagonists; Analysis of Variance; Animals; Carbazoles; Carvedilol; Collagen; Combined Modality Therapy; Disease Models, Animal; Heart Failure; Male; Metoprolol; Mice; Myocytes, Cardiac; Physical Conditioning, Animal; Propanolamines; Random Allocation; Ventricular Remodeling | 2010 |
Carvedilol administration in acute myocardial infarction results in stronger inhibition of early markers of left ventricular remodeling than metoprolol.
Topics: Animals; Biomarkers; Carbazoles; Carvedilol; Down-Regulation; Metoprolol; Myocardial Infarction; Propanolamines; Random Allocation; Swine; Ventricular Remodeling | 2011 |
Effect of left ventricular reverse remodeling on long-term prognosis after therapy with angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers and β blockers in patients with idiopathic dilated cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Dose-Response Relationship, Drug; Drug Therapy, Combination; Echocardiography; Female; Heart Transplantation; Humans; Male; Metoprolol; Middle Aged; Prognosis; Propanolamines; Retrospective Studies; Survival Rate; Ventricular Function, Left; Ventricular Remodeling | 2011 |
Association of beta-adrenergic receptor polymorphisms and mortality in carvedilol-treated chronic heart-failure patients.
Topics: Aged; Aged, 80 and over; Carbazoles; Carvedilol; Female; Genotype; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Pharmacogenetics; Polymorphism, Genetic; Propanolamines; Proportional Hazards Models; Receptors, Adrenergic, beta; Survival Analysis | 2011 |
Carvedilol and its new analogs suppress arrhythmogenic store overload-induced Ca2+ release.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bisoprolol; Calcium; Calcium Channel Blockers; Carbazoles; Carvedilol; Cell Line; Drug Therapy, Combination; Electrocardiography; Gene Knock-In Techniques; Humans; Metoprolol; Mice; Mice, Mutant Strains; Microscopy, Confocal; Mutation, Missense; Propanolamines; Ryanodine Receptor Calcium Release Channel | 2011 |
Beta-blockers for heart failure: why you should use them more.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Clinical Trials as Topic; Evidence-Based Medicine; Heart Failure, Systolic; Humans; Metoprolol; Practice Guidelines as Topic; Propanolamines; Treatment Outcome | 2011 |
Persistence with nebivolol in the treatment of hypertension: a retrospective claims analysis.
Topics: Adult; Aged; Antihypertensive Agents; Atenolol; Benzopyrans; Carbazoles; Carvedilol; Databases, Factual; Ethanolamines; Female; Humans; Hypertension; Insurance Claim Review; Male; Metoprolol; Middle Aged; Nebivolol; Propanolamines; Retrospective Studies | 2012 |
β-Adrenergic receptor antagonists ameliorate myocyte T-tubule remodeling following myocardial infarction.
Topics: Adrenergic beta-Antagonists; Animals; Carbazoles; Carvedilol; Caveolin 3; Male; Membrane Proteins; Metoprolol; Mice; Myocardial Infarction; Myocytes, Cardiac; Propanolamines; Ventricular Remodeling | 2012 |
Effect of oxidative stress on ventricular arrhythmia in rabbits with adriamycin-induced cardiomyopathy.
Topics: Animals; Anti-Arrhythmia Agents; Antibiotics, Antineoplastic; Carbazoles; Cardiomyopathies; Carvedilol; Doxorubicin; Heart Rate; Male; Metoprolol; Oxidative Stress; Propanolamines; Rabbits; Treatment Outcome; Ventricular Fibrillation | 2012 |
Carvedilol reduces the severity of atherosclerosis in apolipoprotein E-deficient mice via reducing superoxide production.
Topics: Adrenergic beta-Antagonists; Animals; Aorta; Apolipoproteins E; Atherosclerosis; Blood Pressure; Carbazoles; Carvedilol; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cholesterol, Dietary; Free Radicals; Heart Rate; Lipids; Macrophages; Male; Metoprolol; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Plaque, Atherosclerotic; Propanolamines; Propranolol; Superoxides | 2012 |
The natural history of new-onset heart failure with a severely depressed left ventricular ejection fraction: implications for timing of implantable cardioverter-defibrillator implantation.
Topics: Adrenergic beta-Antagonists; Adult; Carbazoles; Carvedilol; Cohort Studies; Defibrillators, Implantable; Echocardiography; Female; Follow-Up Studies; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Stroke Volume; Survival Rate; Time Factors; Treatment Outcome | 2012 |
Carvedilol or sustained-release metoprolol for congestive heart failure: a comparative effectiveness analysis.
Topics: Adrenergic beta-Antagonists; Carbazoles; Cardiomyopathies; Carvedilol; Cohort Studies; Delayed-Action Preparations; Female; Follow-Up Studies; Heart Failure; Hospitalization; Humans; Male; Metoprolol; Middle Aged; Myocardial Ischemia; Propanolamines; Proportional Hazards Models; Stroke Volume | 2012 |
Update on pharmacological advances.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Carbazoles; Carvedilol; Disease Progression; Heart Failure; Humans; Metoprolol; Myocardial Infarction; Propanolamines; Recurrence; Ventricular Dysfunction, Left | 2004 |
[Economic analysis of the treatment of heart failure with beta-blockers].
Topics: Adrenergic beta-Antagonists; Benzopyrans; Bisoprolol; Carbazoles; Carvedilol; Clinical Trials as Topic; Cost-Benefit Analysis; Drug Costs; Ethanolamines; Heart Failure; Hospitalization; Humans; Meta-Analysis as Topic; Metoprolol; Nebivolol; Propanolamines | 2013 |
Chronotropic incompetence: real life observations of a theoretical concept.
Topics: Adrenergic beta-1 Receptor Antagonists; Amiodarone; Anti-Arrhythmia Agents; Carbazoles; Carvedilol; Exercise Test; Exercise Tolerance; Female; Heart Failure; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Vasodilator Agents | 2013 |
Differential effects of the β-adrenoceptor blockers carvedilol and metoprolol on SQT1- and SQT2-mutant channels.
Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Carbazoles; Carvedilol; CHO Cells; Cricetulus; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Heart Conduction System; Heart Defects, Congenital; HEK293 Cells; Humans; KCNQ1 Potassium Channel; Kinetics; Metoprolol; Mutation; Potassium; Potassium Channel Blockers; Propanolamines; Transfection | 2013 |
Inappropriate implantable defibrillator shocks: an adverse outcome that can be prevented.
Topics: Carbazoles; Cardiac Resynchronization Therapy; Carvedilol; Defibrillators, Implantable; Female; Heart Failure; Humans; Male; Metoprolol; Propanolamines | 2013 |
Risk of emergent bradycardia associated with the use of carvedilol and metoprolol in routine clinical practice.
Topics: Adrenergic alpha-1 Receptor Antagonists; Bradycardia; California; Carbazoles; Carvedilol; Comorbidity; Female; Humans; Incidence; Male; Metoprolol; Middle Aged; Propanolamines; Proportional Hazards Models; Risk Factors | 2013 |
Anti-inflammatory and pro-angiogenic effects of beta blockers in a canine model of chronic ischemic cardiomyopathy: comparison between carvedilol and metoprolol.
Topics: Adrenergic beta-Antagonists; Animals; Carbazoles; Carvedilol; Dogs; Echocardiography; Heart; Immunohistochemistry; Interleukin-10; Metoprolol; Myocardial Ischemia; Oxidative Stress; Propanolamines | 2013 |
The large-scale placebo-controlled beta-blocker studies in systolic heart failure revisited: results from CIBIS-II, COPERNICUS and SENIORS-SHF compared with stratified subsets from MERIT-HF.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Benzopyrans; Bisoprolol; Carbazoles; Carvedilol; Delayed-Action Preparations; Ethanolamines; Female; Heart Failure, Systolic; Hospitalization; Humans; Male; Metoprolol; Middle Aged; Nebivolol; Propanolamines; Randomized Controlled Trials as Topic; Risk; Severity of Illness Index; Stroke Volume; Treatment Outcome | 2014 |
Carvedilol has stronger anti-inflammation and anti-virus effects than metoprolol in murine model with coxsackievirus B3-induced viral myocarditis.
Topics: Animals; Anti-Arrhythmia Agents; Carbazoles; Carvedilol; Cytokines; Enterovirus B, Human; Metoprolol; Mice; Mice, Inbred BALB C; Myocarditis; p38 Mitogen-Activated Protein Kinases; Propanolamines | 2014 |
Adenylyl cyclase signaling in the developing chick heart: the deranging effect of antiarrhythmic drugs.
Topics: Adenylyl Cyclases; Animals; Anti-Arrhythmia Agents; Carbazoles; Carvedilol; Chick Embryo; Chickens; Gene Expression Regulation; Heart; Metoprolol; Myocardium; Propanolamines; Signal Transduction | 2014 |
Human and simulated intestinal fluids as solvent systems to explore food effects on intestinal solubility and permeability.
Topics: Animals; Atenolol; Body Fluids; Carbazoles; Carvedilol; Humans; Intestinal Secretions; Male; Metoprolol; Permeability; Propanolamines; Propranolol; Rats; Rats, Sprague-Dawley; Solubility; Solvents | 2014 |
Association of treatment with carvedilol vs metoprolol succinate and mortality in patients with heart failure.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Carbazoles; Carvedilol; Denmark; Female; Follow-Up Studies; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Odds Ratio; Propanolamines; Propensity Score; Proportional Hazards Models; Stroke Volume; Treatment Outcome; Ventricular Function, Left | 2014 |
A clinical study about contrast nephropathy: risk factors and the role of beta blockers.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Contrast Media; Cross-Sectional Studies; Female; Humans; Kidney Diseases; Logistic Models; Male; Metoprolol; Middle Aged; Myocardial Infarction; Nebivolol; Propanolamines; Prospective Studies; Protective Agents; Radiography; Treatment Outcome; Vasodilator Agents | 2015 |
Influence of Different β-Blockers on Platelet Aggregation in Patients With Coronary Artery Disease on Dual Antiplatelet Therapy.
Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Aspirin; Bisoprolol; Carbazoles; Carvedilol; Clopidogrel; Coronary Artery Disease; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Metoprolol; Middle Aged; Nebivolol; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Propanolamines; Prospective Studies; Ticlopidine; Treatment Outcome | 2016 |
Comparison of metoprolol succinate versus carvedilol in time to cardiovascular admission in a Veterans Affairs healthcare system: An observational study.
Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Aged, 80 and over; Carbazoles; Carvedilol; Female; Heart Failure; Hospitals, Veterans; Humans; Male; Metoprolol; Middle Aged; Patient Admission; Propanolamines; Retrospective Studies; Time-to-Treatment; United States; United States Department of Veterans Affairs; Veterans | 2015 |
Prognostic Benefits of Carvedilol, Bisoprolol, and Metoprolol Controlled Release/Extended Release in Hemodialysis Patients with Heart Failure: A 10-Year Cohort.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Bisoprolol; Carbazoles; Carvedilol; Chi-Square Distribution; Databases, Factual; Delayed-Action Preparations; Drug Compounding; Female; Heart Failure; Humans; Kaplan-Meier Estimate; Kidney Failure, Chronic; Male; Metoprolol; Middle Aged; Multivariate Analysis; Propanolamines; Propensity Score; Proportional Hazards Models; Renal Dialysis; Retrospective Studies; Risk Factors; Taiwan; Time Factors; Treatment Outcome | 2016 |
Carvedilol, Bisoprolol, and Metoprolol Use in Patients With Coexistent Heart Failure and Chronic Obstructive Pulmonary Disease.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Bisoprolol; Carbazoles; Carvedilol; Contraindications; Female; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Pulmonary Disease, Chronic Obstructive; Retrospective Studies; Taiwan; Young Adult | 2016 |
Older adults with heart failure treated with carvedilol, bisoprolol, or metoprolol tartrate: risk of mortality.
Topics: Adrenergic beta-Antagonists; Aged; Bisoprolol; Carbazoles; Carvedilol; Cohort Studies; Databases, Factual; Female; Follow-Up Studies; Heart Failure; Hospitalization; Humans; Male; Metoprolol; Propanolamines; Propensity Score; Proportional Hazards Models; Quebec; Treatment Outcome | 2017 |
Evaluating the effectiveness of different beta-adrenoceptor blockers in heart failure patients.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Bisoprolol; Carbazoles; Carvedilol; Female; Heart Failure; Hospitalization; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Propensity Score; Proportional Hazards Models; Retrospective Studies; Taiwan; Treatment Outcome | 2017 |
Impact of Beta-Blocker Initiation Timing on Mortality Risk in Patients With Diabetes Mellitus Undergoing Noncardiac Surgery: A Nationwide Population-Based Cohort Study.
Topics: Adrenergic beta-Antagonists; Aged; Atenolol; Bisoprolol; Carbazoles; Carvedilol; Cohort Studies; Databases, Factual; Diabetes Mellitus, Type 2; Female; Hospital Mortality; Humans; Male; Metoprolol; Middle Aged; Mortality; Odds Ratio; Perioperative Care; Propanolamines; Propensity Score; Protective Factors; Risk Factors; Surgical Procedures, Operative; Taiwan; Time Factors | 2017 |
Influence of Peroxide Impurities in Povidone on the Stability of Selected β-Blockers with the Help of HPLC.
Topics: Adrenergic beta-Antagonists; Atenolol; Bisoprolol; Carbazoles; Carvedilol; Chromatography, High Pressure Liquid; Drug Contamination; Drug Stability; Excipients; Metoprolol; Oxidation-Reduction; Peroxides; Povidone; Propanolamines | 2017 |
CYP2D6 Genetic Variation and Beta-Blocker Maintenance Dose in Patients with Heart Failure.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbazoles; Carvedilol; Cytochrome P-450 CYP2D6; Dose-Response Relationship, Drug; Female; Genotype; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Phenotype; Polymorphism, Genetic; Propanolamines; Retrospective Studies | 2017 |
The use of guideline recommended beta-blocker therapy in primary prevention implantable cardioverter defibrillator patients: insight from Danish nationwide registers.
Topics: Adrenergic beta-Antagonists; Aged; Carbazoles; Carvedilol; Death, Sudden, Cardiac; Defibrillators, Implantable; Denmark; Electric Countershock; Female; Guideline Adherence; Humans; Male; Metoprolol; Middle Aged; Practice Guidelines as Topic; Practice Patterns, Physicians'; Primary Prevention; Propanolamines; Retrospective Studies; Risk Factors; Treatment Outcome | 2018 |
Bisoprolol compared with carvedilol and metoprolol succinate in the treatment of patients with chronic heart failure.
Topics: Adrenergic beta-1 Receptor Antagonists; Aged; Aged, 80 and over; Bisoprolol; Carbazoles; Carvedilol; Chronic Disease; England; Female; Follow-Up Studies; Germany; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Norway; Propanolamines; Registries; Treatment Outcome | 2017 |
Analysis of Clinical Efficacy and Adverse Effects of β-Blocking Agents Used Clinically for Chronic Heart Failure.
Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Chronic Disease; Forced Expiratory Volume; Heart Failure; Heart Rate; Humans; Metoprolol; Models, Biological; Propanolamines; Treatment Outcome; Ventricular Function, Left | 2017 |
The evaluation of β-adrenoceptor blocking agents in patients with COPD and congestive heart failure: a nationwide study.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Bisoprolol; Carbazoles; Carvedilol; Chi-Square Distribution; Databases, Factual; Disease Progression; Female; Heart Failure; Hospitalization; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Propensity Score; Proportional Hazards Models; Pulmonary Disease, Chronic Obstructive; Retrospective Studies; Taiwan; Time Factors; Treatment Outcome | 2017 |
Metoprolol, propranolol, carvedilol, or labetalol for patients with Takotsubo syndrome?
Topics: Carvedilol; Humans; Labetalol; Metoprolol; Propranolol; Takotsubo Cardiomyopathy | 2018 |
Reply to: metoprolol, or propranolol, or carvedilol, or labetalol, for patients with takotsubo syndrome?
Topics: Carvedilol; Humans; Labetalol; Metoprolol; Propranolol; Takotsubo Cardiomyopathy | 2018 |
Assessment of the potential drug-drug interaction between carvedilol and clopidogrel mediated through intestinal P-glycoprotein.
Topics: Adrenergic beta-Antagonists; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carbazoles; Carvedilol; Clopidogrel; Drug Interactions; Intestinal Absorption; Intestine, Small; Male; Metoprolol; Perfusion; Permeability; Platelet Aggregation Inhibitors; Propanolamines; Rats; Rats, Wistar; Ticlopidine; Verapamil | 2016 |
A Comparative Study of Carvedilol Versus Metoprolol Initiation and 1-Year Mortality Among Individuals Receiving Maintenance Hemodialysis.
Topics: Adrenergic beta-1 Receptor Antagonists; Aged; Carvedilol; Cohort Studies; Female; Humans; Male; Metoprolol; Middle Aged; Mortality; Renal Dialysis; Renal Insufficiency, Chronic; Retrospective Studies; Time Factors | 2018 |
Importance of beta-blocker dose in prevention of ventricular tachyarrhythmias, heart failure hospitalizations, and death in primary prevention implantable cardioverter-defibrillator recipients: a Danish nationwide cohort study.
Topics: Adrenergic beta-Antagonists; Aged; Carvedilol; Death, Sudden, Cardiac; Defibrillators, Implantable; Denmark; Dose-Response Relationship, Drug; Electric Countershock; Female; Heart Failure; Hospitalization; Humans; Male; Metoprolol; Middle Aged; Primary Prevention; Registries; Retrospective Studies; Risk Assessment; Risk Factors; Tachycardia, Ventricular; Time Factors; Treatment Outcome; Ventricular Fibrillation | 2018 |
Effects of Carvedilol Versus Metoprolol on Platelet Aggregation in Patients With Acute Coronary Syndrome: The PLATE-BLOCK Study.
Topics: Acute Coronary Syndrome; Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-1 Receptor Antagonists; Blood Platelets; Carvedilol; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Male; Metoprolol; Middle Aged; Platelet Aggregation; Platelet Function Tests; Prospective Studies; Treatment Outcome | 2018 |
β-blockers interfere with cell homing receptors and regulatory proteins in a model of spontaneously hypertensive rats.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Atenolol; beta-Arrestin 1; beta-Arrestin 2; Carbazoles; Carvedilol; Cell Movement; Chemokine CXCL12; Disease Models, Animal; G-Protein-Coupled Receptor Kinase 2; Hypertension; Kidney; Liver; Lung; Metoprolol; Myocardium; NF-kappa B; Propanolamines; Propranolol; Rats, Inbred SHR; Receptors, CXCR; Receptors, CXCR4; Signal Transduction | 2018 |
Effect of carvedilol vs metoprolol succinate on mortality in heart failure with reduced ejection fraction.
Topics: Adrenergic beta-Antagonists; Aged; Carvedilol; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Heart Failure; Humans; Male; Metoprolol; Propensity Score; Retrospective Studies; Stroke Volume; Survival Rate; United States | 2018 |
Beta blockers and chronic heart failure patients: prognostic impact of a dose targeted beta blocker therapy vs. heart rate targeted strategy.
Topics: Adrenergic beta-Antagonists; Carvedilol; Cause of Death; Female; Follow-Up Studies; Germany; Heart Failure, Systolic; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Prognosis; Retrospective Studies; Stroke Volume; Survival Rate; Time Factors | 2018 |
Effect on Mortality of Higher Versus Lower β-Blocker (Metoprolol Succinate or Carvedilol) Dose in Patients With Heart Failure.
Topics: Adrenergic beta-Antagonists; Aged; Carvedilol; Female; Heart Failure; Heart Rate; Humans; Male; Metoprolol; Propensity Score; Stroke Volume; United States; Veterans | 2018 |
Heterogeneity in Outcomes Among β-Blockers Elucidated by Intradialytic Data.
Topics: Adrenergic beta-Antagonists; Carvedilol; Humans; Metoprolol; Renal Dialysis | 2018 |
Insights on β-blockers for the treatment of hypertension: A survey of health care practitioners.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Antihypertensive Agents; Atenolol; Black or African American; Cardiologists; Carvedilol; Heart Rate; Humans; Hypertension; Metoprolol; Nebivolol; Perception; Physicians, Primary Care; Practice Guidelines as Topic; Surveys and Questionnaires; Vasodilation | 2018 |
Low Utilization of Beta-Blockers Among Medicare Beneficiaries Hospitalized for Heart Failure With Reduced Ejection Fraction.
Topics: Adrenergic beta-1 Receptor Antagonists; Aged; Bisoprolol; Carvedilol; Cohort Studies; Drug Prescriptions; Female; Heart Failure; Humans; Male; Medicare Part D; Medication Adherence; Metoprolol; Retrospective Studies; Stroke Volume; United States | 2019 |
A comparison of anti-arrhythmic efficacy of carvedilol vs metoprolol succinate in patients with implantable cardioverter-defibrillators.
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arkansas; Carvedilol; Cause of Death; Death, Sudden, Cardiac; Defibrillators, Implantable; Female; Follow-Up Studies; Heart Failure; Humans; Incidence; Male; Metoprolol; Middle Aged; Retrospective Studies; Risk Factors; Survival Rate; Treatment Outcome; Ventricular Function, Left | 2019 |
β-Blockers and 1-Year Postdischarge Mortality for Heart Failure and Reduced Ejection Fraction and Slow Discharge Heart Rate.
Topics: Adrenergic beta-Antagonists; Aged; Bisoprolol; Carvedilol; Female; Follow-Up Studies; Heart Failure; Heart Rate; Humans; Male; Metoprolol; Nebivolol; Patient Discharge; Prospective Studies; Republic of Korea; Stroke Volume; Survival Rate; Time Factors; Treatment Outcome | 2019 |
Acute effects of intravenous carvedilol versus metoprolol on baroreflex-mediated sympathetic circulatory regulation in rats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-1 Receptor Antagonists; Animals; Baroreflex; Blood Pressure; Carvedilol; Disease Models, Animal; Dose-Response Relationship, Drug; Electrocardiography; Heart Failure; Heart Rate; Injections, Intravenous; Male; Metoprolol; Rats; Rats, Inbred WKY; Sympathetic Nervous System; Treatment Outcome | 2019 |
Beta-blocker choice and exchangeability in patients with heart failure and chronic obstructive pulmonary disease: an Italian register-based cohort study.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Atrioventricular Block; Bisoprolol; Carvedilol; Cerebrovascular Disorders; Cohort Studies; Comorbidity; Drug Prescriptions; Drug Substitution; Drug Utilization; Female; Heart Failure; Hospitalization; Humans; Italy; Male; Metoprolol; Nebivolol; Practice Guidelines as Topic; Pulmonary Disease, Chronic Obstructive; Registries; Renal Insufficiency, Chronic; Retrospective Studies; Thrombosis | 2019 |
High-throughput quantification of ten antiarrhythmic drugs in human plasma using UPLC-MS/MS.
Topics: Anti-Arrhythmia Agents; Atenolol; Bisoprolol; Carvedilol; Chromatography, High Pressure Liquid; Diltiazem; Flecainide; High-Throughput Screening Assays; Humans; Lidocaine; Metoprolol; Propranolol; Reproducibility of Results; Sotalol; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Verapamil | 2019 |
Metoprolol Versus Carvedilol in Patients With Heart Failure, Chronic Obstructive Pulmonary Disease, Diabetes Mellitus, and Renal Failure.
Topics: Acute Disease; Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-1 Receptor Antagonists; Aged; Carvedilol; Comorbidity; Denmark; Female; Follow-Up Studies; Heart Failure; Humans; Male; Metoprolol; Pulmonary Disease, Chronic Obstructive; Renal Insufficiency; Retrospective Studies; Survival Rate | 2020 |
Carvedilol and metoprolol are both able to preserve myocardial function in type 2 diabetes.
Topics: Adrenergic beta-1 Receptor Antagonists; Aged; Animals; Carvedilol; Coronary Artery Bypass; Diabetes Mellitus, Type 2; Disease Models, Animal; Female; Heart; Humans; Male; Metoprolol; Middle Aged; Rats, Zucker; Treatment Outcome | 2020 |
Use of beta-blocker types and risk of incident prostate cancer in a multiethnic population.
Topics: Adrenergic beta-Antagonists; Aged; Atenolol; Carvedilol; Humans; Image-Guided Biopsy; Incidence; Male; Metoprolol; Middle Aged; Prostate; Prostatic Neoplasms; Protective Factors; Retrospective Studies; Risk Assessment; Time Factors; Ultrasonography, Interventional | 2020 |
β-Blocker Use and Risk of Mortality in Heart Failure Patients Initiating Maintenance Dialysis.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Atenolol; Bisoprolol; Carvedilol; Cause of Death; Cohort Studies; Female; Heart Failure; Hospitalization; Humans; Kidney Failure, Chronic; Labetalol; Logistic Models; Male; Metoprolol; Middle Aged; Mortality; Nadolol; Proportional Hazards Models; Propranolol; Protective Factors; Renal Dialysis; Retrospective Studies; Risk; Risk Factors | 2021 |
The effects of carvedilol, metoprolol and propranolol on cisplatin-induced kidney injury.
Topics: Adrenergic beta-Antagonists; Animals; Carvedilol; Cisplatin; Creatinine; Kidney; Metoprolol; Propranolol; Rats; Technetium Tc 99m Dimercaptosuccinic Acid | 2022 |
Beta-blockers utilization in heart failure patients: Sub-analysis of a nation-wide population-based study in the Czech Republic.
Topics: Adrenergic beta-Antagonists; Betaxolol; Bisoprolol; Carbazoles; Carvedilol; Czech Republic; Heart Failure; Humans; Metoprolol; Nebivolol; Propanolamines; Retrospective Studies | 2021 |
β-blockade prevents coronary macro- and microvascular dysfunction induced by a high salt diet and insulin resistance in the Goto-Kakizaki rat.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Carvedilol; Coronary Angiography; Diabetes Mellitus, Type 2; Disease Models, Animal; Endothelium, Vascular; Hypertension; Insulin Resistance; Male; Metoprolol; Nitric Oxide; Rats; Rats, Wistar; Sodium Chloride, Dietary | 2021 |
Comparison of Metoprolol Versus Carvedilol After Acute Myocardial Infarction.
Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Carvedilol; Female; Hospitalization; Humans; Kaplan-Meier Estimate; Male; Metoprolol; Middle Aged; Myocardial Infarction; Registries; Stroke Volume; Survival Rate; Treatment Outcome | 2021 |
Effects of carvedilol and metoprolol on the myocardium during mechanical unloading in a rat heterotopic heart transplantation model.
Topics: Adrenergic beta-Antagonists; Animals; Carvedilol; Heart Failure; Heart Transplantation; Metoprolol; Myocardium; Rats; Ventricular Function, Left | 2021 |
Therapeutic Inefficacy and Proarrhythmic Nature of Metoprolol Succinate and Carvedilol Therapy in Patients With Idiopathic, Frequent, Monomorphic Premature Ventricular Contractions.
Topics: Anti-Arrhythmia Agents; Carvedilol; Electrocardiography, Ambulatory; Humans; Metoprolol; Ventricular Premature Complexes | 2021 |
Comparison of carvedilol versus metoprolol in patients with acute myocardial infarction: A protocol for systematic review and meta-analysis.
Topics: Arrhythmias, Cardiac; Carvedilol; Death, Sudden, Cardiac; Humans; Meta-Analysis as Topic; Metoprolol; Myocardial Infarction; Patient Readmission; Randomized Controlled Trials as Topic; Recurrence; Systematic Reviews as Topic; Treatment Outcome | 2021 |
Risk of clinically relevant hyperglycemia with metoprolol compared to carvedilol in older adults with heart failure and diabetes.
Topics: Aged; Carvedilol; Diabetes Mellitus; Heart Failure; Humans; Hyperglycemia; Male; Medicare; Metoprolol; Retrospective Studies; United States | 2021 |
Long-Term Mortality Associated With Use of Carvedilol Versus Metoprolol in Heart Failure Patients With and Without Type 2 Diabetes: A Danish Nationwide Cohort Study.
Topics: Aged; Carvedilol; Denmark; Diabetes Mellitus, Type 2; Female; Heart Failure; Humans; Male; Metoprolol; Retrospective Studies; Stroke Volume | 2021 |
Blood pressure response to commonly administered antihypertensives for severe inpatient hypertension.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Carvedilol; Cohort Studies; Humans; Hydralazine; Hypertension; Inpatients; Metoprolol | 2022 |
Guideline-Directed Medical Therapy in Newly Diagnosed Heart Failure With Reduced Ejection Fraction in the Community.
Topics: Adrenergic beta-Antagonists; Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Bisoprolol; Carvedilol; Female; Heart Failure; Humans; Male; Metoprolol; Mineralocorticoid Receptor Antagonists; Neprilysin; Receptors, Angiotensin; Retrospective Studies; Stroke Volume; Treatment Outcome | 2022 |
Comparison of new-onset post-operative atrial fibrillation between patients receiving carvedilol and metoprolol after off-pump coronary artery bypass graft surgery.
Topics: Adrenergic beta-Antagonists; Adult; Atrial Fibrillation; Bradycardia; Carvedilol; Coronary Artery Bypass, Off-Pump; Female; Humans; Hypotension; Male; Metoprolol; Middle Aged; Postoperative Complications; Retrospective Studies; Risk Factors | 2023 |
Diagnosis of new-onset postoperative atrial fibrillation is important.
Topics: Atrial Fibrillation; Carvedilol; Coronary Artery Bypass, Off-Pump; Humans; Metoprolol; Risk Factors | 2023 |
α/β- and β-Blocker Exposure in Pregnancy and the Risk of Neonatal Hypoglycemia and Small for Gestational Age.
Topics: Adrenergic beta-Antagonists; Carvedilol; Female; Gestational Age; Humans; Hypoglycemia; Infant, Newborn; Metoprolol; Pregnancy | 2023 |
Impact of Diabetes Mellitus on Benefit of β-Blocker Therapy After Myocardial Infarction.
Topics: Adrenergic beta-Antagonists; Carvedilol; Diabetes Mellitus; Humans; Metoprolol; Myocardial Infarction | 2023 |
Effect of Carvedilol vs Metoprolol on Atrial and Ventricular Arrhythmias Among Implantable Cardioverter-Defibrillator Recipients.
Topics: Adrenergic beta-Antagonists; Atrial Fibrillation; Carvedilol; Defibrillators, Implantable; Heart Failure; Humans; Metoprolol; Tachycardia, Ventricular | 2023 |
Differential Effects of the Betablockers Carvedilol, Metoprolol and Bisoprolol on Cardiac K
Topics: Bisoprolol; Carvedilol; Heart; Heart Failure; Humans; Metoprolol; Protein Isoforms | 2023 |
Improved Cardiac Performance and Decreased Arrhythmia in Hypertrophic Cardiomyopathy With Non-β-Blocking R-Enantiomer Carvedilol.
Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Cardiomyopathy, Hypertrophic; Carvedilol; Humans; Metoprolol; Mice; Myocytes, Cardiac; Receptors, Adrenergic; Ryanodine Receptor Calcium Release Channel; Verapamil | 2023 |
The role of plasma concentrations and drug characteristics of beta-blockers in fall risk of older persons.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Carvedilol; Humans; Metoprolol | 2023 |