Compounds > carvedilol

carvedilol and allopurinol

carvedilol has been researched along with allopurinol in 13 studies

Research

Studies (13)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (15.38)	18.2507
2000's	6 (46.15)	29.6817
2010's	5 (38.46)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Cheng, HY; Feuerstein, GZ; Gu, JL; McKenna, PJ; Ruffolo, RE; Yue, TL	1
Feuerstein, R; Yue, TL	1
Moreno, AJ; Oliveira, PJ; Palmeira, CM; Rolo, AP	1
Gonçalves, L; Monteiro, P; Moreno, AJ; Oliveira, PJ; Palmeira, CM; Rolo, AP	1
Alfany-Fernandez, I; Ben Abdennebi, H; Ben Mosbah, I; Boillot, O; Lojek, A; Mitjavila, MT; Parellada, PP; Peralta, C; Rimola, A; Rodés, J; Roselló-Catafau, J	1

Reviews

1 review(s) available for carvedilol and allopurinol

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

12 other study(ies) available for carvedilol and allopurinol

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Carvedilol, a new vasodilating beta adrenoceptor blocker antihypertensive drug, protects endothelial cells from damage initiated by xanthine-xanthine oxidase and neutrophils. Cardiovascular research, 1994, Volume: 28, Issue:3 Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Carbazoles; Carvedilol; Cattle; Cells, Cultured; Electron Spin Resonance Spectroscopy; Endothelium, Vascular; Humans; L-Lactate Dehydrogenase; Neutrophils; Propanolamines; Pulmonary Artery; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Vasodilator Agents; Xanthine; Xanthine Oxidase; Xanthines	1994
A potent antioxidant, SB209995, inhibits oxygen-radical-mediated lipid peroxidation and cytotoxicity. Pharmacology, 1994, Volume: 48, Issue:6 Topics: Animals; Antioxidants; Brain; Carbazoles; Carvedilol; Cattle; Cells, Cultured; Endothelium, Vascular; Free Radicals; Humans; Hydroxyl Radical; Lipid Peroxidation; Lipoproteins, LDL; Oxygen; Propanolamines; Rats; Superoxides; Xanthine Oxidase	1994
Carvedilol reduces mitochondrial damage induced by hypoxanthine/xanthine oxidase: relevance to hypoxia/reoxygenation injury. Cardiovascular toxicology, 2001, Volume: 1, Issue:3 Topics: Adrenergic beta-Antagonists; Animals; Calcium; Carbazoles; Carvedilol; Cyclosporine; Hypoxanthine; Hypoxia; Male; Membrane Potentials; Mitochondria, Heart; Mitochondrial Swelling; Oxidative Stress; Oxygen Consumption; Propanolamines; Rats; Superoxides; Xanthine Oxidase	2001
Impact of carvedilol on the mitochondrial damage induced by hypoxanthine and xantine oxidase--what role in myocardial ischemia and reperfusion? Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology, 2002, Volume: 21, Issue:12 Topics: Animals; Antioxidants; Carbazoles; Carvedilol; Hypoxanthine; Male; Mitochondria, Heart; Myocardial Ischemia; Myocardial Reperfusion; Propanolamines; Rats; Rats, Wistar; Xanthine Oxidase	2002
Addition of carvedilol to University Wisconsin solution improves rat steatotic and nonsteatotic liver preservation. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2010, Volume: 16, Issue:2 Topics: Adenosine; Adenosine Triphosphate; Adenylate Kinase; Adrenergic beta-Antagonists; Allopurinol; Animals; Bile; Carbazoles; Carvedilol; Cold Temperature; Fatty Liver; Glutathione; Insulin; Liver; Liver Function Tests; Liver Transplantation; Organ Preservation; Organ Preservation Solutions; Postoperative Complications; Propanolamines; Raffinose; Rats; Rats, Zucker; Reperfusion Injury; Vascular Resistance	2010