carnosine has been researched along with n-acetylcarnosine in 53 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (7.55) | 18.7374 |
| 1990's | 5 (9.43) | 18.2507 |
| 2000's | 19 (35.85) | 29.6817 |
| 2010's | 22 (41.51) | 24.3611 |
| 2020's | 3 (5.66) | 2.80 |
| Authors | Studies |
|---|---|
| Miller, DJ; O'Dowd, JJ; Robins, DJ | 1 |
| Kunimi, H; Okabe, S | 3 |
| Babizhayev, MA; Evstigneeva, RP; Rozhkova, EA; Sakina, NL; Yermakova, VN; Zheltukhina, GA | 1 |
| Alabovskiĭ, VV; Boldyrev, AA; Chesnokov, DN; Gallant, S; Vinokurov, AA | 1 |
| Abe, H; Ikeda, D; Wada, S; Watabe, S; Yoneda, C | 1 |
| Alabovskiĭ, VV; Boldyrev, AA; Chesnokov, DN; Dmitrashchuk, AI; Vinokurov, AA | 1 |
| Boldyrev, A; Carpenter, DO; Lawrence, D; Song, R | 1 |
| Abe, H; Bohan, NA; Boldyrev, AA; Johnson, P; Prokopieva, VD | 1 |
| Babizhayev, MA; Deyev, AI; Semiletov, YA; Yermakova, VN | 1 |
| Babizhayev, MA; Davydova, NG; Deyev, AI; Goldman, IM; Kurysheva, NI; Semiletov, YA; Yermakova, VN; Zhukotskii, AV | 1 |
| Babizhayev, MA; Davydova, NG; Deyev, AI; Doroshenko, VS; Goldman, IM; Semiletov, YA; Yermakova, VN; Zhukotskii, AV | 1 |
| Aldini, G; Beretta, G; Bradamante, S; Carini, M; Facino, RM | 1 |
| Babizhayev, MA; Bours, J; Brikman, IV; Deyev, AI; Yermakova, VN | 1 |
| Babizhayev, MA | 11 |
| Borin, G; Calderan, A; Guiotto, A; Ruzza, P | 1 |
| Babizhayev, MA; Guiotto, A; Kasus-Jacobi, A | 1 |
| Alikhanov, SA; Artyukhina, TV; Arzumanyan, ES; Bokeriya, LA; Boldyrev, AA; Movsesyan, RR; Nisnevich, ED; Serov, RA | 1 |
| Akiyama, N; Natori, S; Nishigori, H; Sogo, S; Tsujimoto, M; Umeda, IO | 1 |
| Babizhayev, MA; Kasus-Jacobi, A | 1 |
| Chen, HL; Hang, CH; Lin, YX; Lu, H; Shi, JX; Yin, HX; Zhang, DM | 1 |
| Aldini, G; Carini, M; Orioli, M; Rasmussen, H; Regazzoni, L; Russell, RM; Yeum, KJ | 1 |
| Babizhayev, MA; Burke, L; Micans, P; Richer, SP | 1 |
| Babizhayev, MA; Yegorov, YE | 6 |
| Downard, KM; Ha, JW; Schwahn, AB | 1 |
| Babizhayev, MA; Kasus-Jacobi, A; Khoroshilova-Maslova, IP | 1 |
| Calhoun, J; Cebulla, CM; Cloud, A; Tandon, A | 1 |
| Goebel, AS; Neubert, RH; Schmaus, G; Wohlrab, J | 1 |
| Boldyrev, AA; Dizhevskaya, AK; Muranov, KO; Ostrovsky, MA | 1 |
| Babizhayev, MA; Kasus-Jacobi, A; Vishnyakova, KS; Yegorov, YE | 1 |
| Avetisov, SÉ; Muranov, KO; Ostrovskiĭ, MA; Polianskiĭ, NB; Polunin, GS; Sheremet, NL | 1 |
| Bastawrous, A; Dubois, VD | 1 |
| Huang, X; Liu, W; Wang, L | 1 |
| Hu, H; Peng, T; Wang, Y; Xia, R | 1 |
| Abood, A; Abou Taleb, S; Darwish, AB; Mohamed, AM | 1 |
| Ashok, A; Chaudhary, S; Kang, MH; Kritikos, AE; McDonald, D; Rhee, DJ; Singh, N | 1 |
| Ali, R; Badawi, A; Khalil, R; Mohammed, M; Taleb, SA | 1 |
14 review(s) available for carnosine and n-acetylcarnosine
| Article | Year |
|---|---|
Lipid peroxidation and cataracts: N-acetylcarnosine as a therapeutic tool to manage age-related cataracts in human and in canine eyes.
Topics: Aging; Animals; Carnosine; Cataract; Dog Diseases; Dogs; Humans; Lipid Peroxidation; Randomized Controlled Trials as Topic | 2004 |
Carnosine and carnosine-related antioxidants: a review.
Topics: Aldehydes; Animals; Antioxidants; Carnosine; Dipeptidases; Glycation End Products, Advanced; Humans; Structure-Activity Relationship | 2005 |
Current ocular drug delivery challenges for N-acetylcarnosine: novel patented routes and modes of delivery, design for enhancement of therapeutic activity and drug delivery relationships.
Topics: Administration, Topical; Antioxidants; Carnosine; Drug Delivery Systems; Eye Diseases; Humans; Ophthalmic Solutions; Patents as Topic | 2009 |
Therapeutic uses of drug-carrier systems for imidazole-containing dipeptide compounds that act as pharmacological chaperones and have significant impact on the treatment of chronic diseases associated with increased oxidative stress and the formation of a
Topics: Aging; Animals; Biomarkers; Carnosine; Chemistry, Pharmaceutical; Chronic Disease; Drug Carriers; Drug Compounding; Drug Design; Eye Diseases; Glycation End Products, Advanced; Humans; Lens, Crystalline; Lipid Peroxidation; Models, Molecular; Molecular Structure; Oxidative Stress; Skin; Skin Aging; Skin Diseases; Structure-Activity Relationship | 2010 |
Telomere attrition in lens epithelial cells - a target for N-acetylcarnosine therapy.
Topics: Aged; Animals; Carnosine; Cataract; Disease Models, Animal; Humans; Lens, Crystalline; Telomere; Vision, Ocular; Visual Acuity | 2010 |
Designation of imidazole-containing dipeptides as pharmacological chaperones.
Topics: Carnosine; Cataract; Drug Carriers; Humans; Imidazoles; Lipid Peroxidation; Macular Degeneration; Molecular Chaperones; Oxidative Stress | 2011 |
Advanced drug delivery of N-acetylcarnosine (N-acetyl-beta-alanyl-L-histidine), carcinine (beta-alanylhistamine) and L-carnosine (beta-alanyl-L-histidine) in targeting peptide compounds as pharmacological chaperones for use in tissue engineering, human di
Topics: Animals; Carnosine; Drug Delivery Systems; Heat-Shock Proteins; Humans; Molecular Chaperones; Patents as Topic; Protein Folding; Tissue Engineering | 2010 |
Novel intraocular and systemic absorption drug delivery and efficacy of N-acetylcarnosine lubricant eye drops or carcinine biologics in pharmaceutical usage and therapeutic vision care.
Topics: Administration, Ophthalmic; Animals; Carnosine; Cataract; Chromatography, High Pressure Liquid; Clinical Trials, Phase II as Topic; Drug Delivery Systems; Eye Diseases; Humans; Prodrugs; Randomized Controlled Trials as Topic; Vitreoretinopathy, Proliferative | 2012 |
Biomarkers and special features of oxidative stress in the anterior segment of the eye linked to lens cataract and the trabecular meshwork injury in primary open-angle glaucoma: challenges of dual combination therapy with N-acetylcarnosine lubricant eye d
Topics: Administration, Ophthalmic; Administration, Oral; Animals; Biomarkers; Blindness; Carnosine; Cataract; Glaucoma, Open-Angle; Humans; Ophthalmic Solutions; Oxidative Stress; Trabecular Meshwork | 2012 |
Structural and functional properties, chaperone activity and posttranslational modifications of alpha-crystallin and its related subunits in the crystalline lens: N-acetylcarnosine, carnosine and carcinine act as alpha- crystallin/small heat shock protein
Topics: Age Factors; alpha-Crystallins; Animals; Carnosine; Cataract; Drug Design; Humans; Lens, Crystalline; Molecular Chaperones; Oxidative Stress; Patents as Topic | 2012 |
Biomarkers of oxidative stress and cataract. Novel drug delivery therapeutic strategies targeting telomere reduction and the expression of telomerase activity in the lens epithelial cells with N-acetylcarnosine lubricant eye drops: anti-cataract which hel
Topics: Administration, Ophthalmic; Animals; Antioxidants; Biomarkers; Carnosine; Cataract; Cell Membrane; Cellular Senescence; Ceruloplasmin; Chemistry, Pharmaceutical; Dogs; Drug Carriers; Epithelial Cells; Lens, Crystalline; Ophthalmic Solutions; Oxidative Stress; Prodrugs; Technology, Pharmaceutical; Telomerase; Telomere | 2014 |
Novel neuroendocrine and metabolic mechanism provides the patented platform for important rejuvenation therapies: targeted therapy of telomere attrition and lifestyle changes of telomerase activity with the timing of neuron-specific imidazole-containing d
Topics: Aging; Carnosine; Dipeptides; Humans; Imidazoles; Life Style; Molecular Targeted Therapy; Patents as Topic; Rejuvenation; Telomere Homeostasis; Telomere Shortening | 2014 |
Telomere Attrition in Human Lens Epithelial Cells Associated with Oxidative Stress Provide a New Therapeutic Target for the Treatment, Dissolving and Prevention of Cataract with N-Acetylcarnosine Lubricant Eye Drops. Kinetic, Pharmacological and Activity-
Topics: Administration, Ophthalmic; Age Factors; Aging; Animals; Antioxidants; Carnosine; Cataract; Cornea; Drug Compounding; Drug Delivery Systems; Epithelial Cells; Humans; Lens, Crystalline; Ocular Absorption; Ophthalmic Solutions; Oxidative Stress; Solubility; Telomere Homeostasis | 2016 |
N-acetylcarnosine (NAC) drops for age-related cataract.
Topics: Aged; Aged, 80 and over; Aging; Carnosine; Cataract; Disease Progression; Humans; Middle Aged; Ophthalmic Solutions; Randomized Controlled Trials as Topic | 2017 |
6 trial(s) available for carnosine and n-acetylcarnosine
| Article | Year |
|---|---|
N-Acetylcarnosine, a natural histidine-containing dipeptide, as a potent ophthalmic drug in treatment of human cataracts.
Topics: Age Factors; Aged; Carnosine; Cataract; Eye; Female; Humans; Lens, Crystalline; Male; Middle Aged; Observer Variation; Oxidative Stress; Sex Factors; Time Factors | 2001 |
Efficacy of N-acetylcarnosine in the treatment of cataracts.
Topics: Aged; Aged, 80 and over; Carnosine; Cataract; Female; Humans; Male; Middle Aged | 2002 |
Rejuvenation of visual functions in older adult drivers and drivers with cataract during a short-term administration of N-acetylcarnosine lubricant eye drops.
Topics: Aged; Automobile Driving; Carnosine; Cataract; Double-Blind Method; Female; Glare; Humans; Male; Middle Aged; Ophthalmic Solutions; Vision Disorders; Visual Acuity | 2004 |
N-Acetylcarnosine and histidyl-hydrazide are potent agents for multitargeted ophthalmic therapy of senile cataracts and diabetic ocular complications.
Topics: Aged; Aged, 80 and over; Aldehydes; Aminooxyacetic Acid; Animals; Biological Availability; Carnosine; Cataract; Cornea; Cross-Over Studies; Diabetes Complications; Disease Models, Animal; Drug Administration Schedule; Drug Delivery Systems; Drug Synergism; Female; Glycosylation; Histidine; Humans; Hydrazines; Lubricants; Male; Middle Aged; Ophthalmic Solutions; Ophthalmologic Surgical Procedures; Ophthalmoscopy; Rabbits | 2009 |
State of the art clinical efficacy and safety evaluation of N-acetylcarnosine dipeptide ophthalmic prodrug. Principles for the delivery, self-bioactivation, molecular targets and interaction with a highly evolved histidyl-hydrazide structure in the treatm
Topics: Administration, Topical; Aged; Aged, 80 and over; Antioxidants; Carnosine; Cataract; Contact Lenses; Double-Blind Method; Drug Delivery Systems; Female; Glycation End Products, Advanced; Glycosylation; Histidine; Humans; Hydrazines; Lipid Peroxidation; Liposomes; Lubricants; Male; Middle Aged; Ophthalmic Solutions; Oxidative Stress; Prodrugs; Visual Acuity | 2009 |
N-Acetylcarnosine sustained drug delivery eye drops to control the signs of ageless vision: glare sensitivity, cataract amelioration and quality of vision currently available treatment for the challenging 50,000-patient population.
Topics: Aged; Aged, 80 and over; Carnosine; Cataract; Delayed-Action Preparations; Female; Glare; Humans; Macular Degeneration; Male; Middle Aged; Ophthalmic Solutions; Vision, Ocular | 2009 |
33 other study(ies) available for carnosine and n-acetylcarnosine
| Article | Year |
|---|---|
Detection, characterisation, and quantification of carnosine and other histidyl derivatives in cardiac and skeletal muscle.
Topics: Animals; Anserine; Carnosine; Chromatography, High Pressure Liquid; Dipeptides; Histidine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Male; Methylhistidines; Muscles; Myocardium; Rana temporaria; Rats; Rats, Inbred Strains | 1988 |
Effects of CL-1700 on duodenal ulcer formation in the rat.
Topics: Animals; Anti-Ulcer Agents; Carnosine; Dipeptides; Duodenal Ulcer; Epirizole; Histamine; Male; Rats; Rats, Inbred Strains | 1982 |
Effects of CL-1700 and its constituents on acute or chronic gastric lesions and gastric secretion in rats.
Topics: Aluminum Hydroxide; Animals; Anti-Ulcer Agents; Aspirin; Carnosine; Dipeptides; Gastric Juice; Histamine; Humans; Indomethacin; Male; Rats; Stomach Ulcer; Stress, Psychological | 1982 |
Effects of N-acetyl-L-carnosine aluminum (CL-1700) on various acute gastric lesions and gastric secretion in rats.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Carnosine; Dipeptides; Gastric Mucosa; Indomethacin; Male; Phenylbutazone; Rats; Rats, Inbred Strains; Stomach; Stomach Ulcer; Stress, Physiological | 1981 |
N alpha-acetylcarnosine is a prodrug of L-carnosine in ophthalmic application as antioxidant.
Topics: Animals; Antioxidants; Carnosine; Chromatography, High Pressure Liquid; Humans; Lens Capsule, Crystalline; Lipid Peroxides; Male; Ophthalmic Solutions; Oxidative Stress; Rabbits; Thiobarbituric Acid Reactive Substances | 1996 |
[Comparison of protective effects of carnosine and acetylcarnosine during cardioplegia].
Topics: Animals; Blood Pressure; Cardioplegic Solutions; Carnosine; Heart Arrest, Induced; In Vitro Techniques; Myocardial Contraction; Myocardial Reperfusion; Myocardium; Myoglobin; Nucleosides; Rats | 1999 |
Carnosine stimulates vimentin expression in cultured rat fibroblasts.
Topics: Amino Acid Sequence; Animals; Anserine; Carnosine; Cell Line; Cell Size; CHO Cells; Cricetinae; Fibroblasts; Intermediate Filaments; Molecular Sequence Data; Molecular Weight; Peptide Fragments; Rats; Sequence Analysis; Up-Regulation; Vimentin | 1999 |
[Protein kinase C inhibitors block contractions of the ischemic myocardium caused by acetylcarnosine].
Topics: Adenine Nucleotides; Alkaloids; Animals; Benzophenanthridines; Carnosine; Enzyme Inhibitors; Indoles; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Myoglobin; Phenanthridines; Protein Kinase C; Rats; Stimulation, Chemical; Ventricular Function, Left; Ventricular Pressure | 1999 |
Carnosine protects against excitotoxic cell death independently of effects on reactive oxygen species.
Topics: Animals; Apoptosis; Carnosine; Cells, Cultured; Kainic Acid; Kinetics; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Rats; Rats, Wistar; Reactive Oxygen Species | 1999 |
Effects of carnosine and related compounds on the stability and morphology of erythrocytes from alcoholics.
Topics: Adult; Alcoholism; Alkanesulfonic Acids; Anti-Ulcer Agents; Buffers; Carnosine; Erythrocytes; Hemolysis; Humans; Male; Middle Aged; Piperazines | 2000 |
The natural histidine-containing dipeptide Nalpha-acetylcarnosine as an antioxidant for ophthalmic use.
Topics: Administration, Topical; Animals; Antioxidants; Carnosine; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Histidine; Lens, Crystalline; Male; Ophthalmic Solutions; Oxidative Stress; Rabbits | 2000 |
Carnosine is a quencher of 4-hydroxy-nonenal: through what mechanism of reaction?
Topics: Aldehydes; Animals; Carnosine; In Vitro Techniques; Lipid Peroxidation; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Models, Biological; Muscle, Skeletal; Oxidation-Reduction; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances | 2002 |
Analysis of lipid peroxidation and electron microscopic survey of maturation stages during human cataractogenesis: pharmacokinetic assay of Can-C N-acetylcarnosine prodrug lubricant eye drops for cataract prevention.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Aqueous Humor; Biological Availability; Carnosine; Cataract; Chromatography, High Pressure Liquid; Female; Humans; Lens, Crystalline; Lipid Peroxidation; Liposomes; Lubrication; Male; Microscopy, Electron; Middle Aged; Ophthalmic Solutions; Prodrugs; Rabbits | 2005 |
Biological activities of the natural imidazole-containing peptidomimetics n-acetylcarnosine, carcinine and L-carnosine in ophthalmic and skin care products.
Topics: Aldehydes; Animals; Aqueous Humor; Carnosine; Chinchilla; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Imidazoles; Lipid Peroxidation; Male; Microsomes; Models, Molecular; Ophthalmic Solutions; Peroxides; Phospholipids; Rabbits; Skin Aging; Skin Care; Superoxide Dismutase; Ultraviolet Rays | 2006 |
Ocular drug metabolism of the bioactivating antioxidant N-acetylcarnosine for vision in ophthalmic prodrug and codrug design and delivery.
Topics: Animals; Antioxidants; Carnosine; Cataract; Chromatography, High Pressure Liquid; Cornea; Drug Design; Eye; Humans; Lens, Crystalline; Lipid Peroxidation; Liposomes; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Prodrugs; Rabbits | 2008 |
Cardioprotective effect of histidine-containing dipeptides in pharmacological cold cardioplegia.
Topics: Animals; Cardioplegic Solutions; Cardiotonic Agents; Carnosine; Cold Temperature; Dipeptides; Hypothermia, Induced; Myocytes, Cardiac; Rats; Rats, Wistar | 2008 |
5-S-GAD, a novel radical scavenging compound, prevents lens opacity development.
Topics: alpha-Crystallins; Animals; Biphenyl Compounds; Carnosine; Cataract; Cells, Cultured; Chick Embryo; Cyclic N-Oxides; Diamide; Dihydroxyphenylalanine; Disease Progression; Dose-Response Relationship, Drug; Free Radical Scavengers; Galactose; Glucocorticoids; Glutathione; Insecta; Lens, Crystalline; Lipid Peroxidation; Male; Oxidative Stress; Picrates; Protein Carbonylation; Rats; Rats, Sprague-Dawley; Spin Labels; Superoxides | 2009 |
N-acetylcysteine suppresses oxidative stress in experimental rats with subarachnoid hemorrhage.
Topics: Analysis of Variance; Animals; Brain Edema; Carnosine; Cerebral Cortex; Disease Models, Animal; Gene Expression Regulation; Glutathione Peroxidase; Lipid Peroxidation; Male; Malondialdehyde; Nervous System Diseases; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Sprague-Dawley; Subarachnoid Hemorrhage; Superoxide Dismutase | 2009 |
Profiling histidine dipeptides in plasma and urine after ingesting beef, chicken or chicken broth in humans.
Topics: Adult; Animals; Anserine; beta-Alanine; Carnosine; Cattle; Chickens; Chromatography, High Pressure Liquid; Female; Humans; Kinetics; Lung; Male; Meat; Middle Aged; Poultry Products; Rats; Rats, Wistar; Tandem Mass Spectrometry | 2010 |
Potentiation of intraocular absorption and drug metabolism of N-acetylcarnosine lubricant eye drops: drug interaction with sight threatening lipid peroxides in the treatment for age-related eye diseases.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antioxidants; Aqueous Humor; Carnosine; Cataract; Delayed-Action Preparations; Drug Synergism; Eye; Female; Humans; Lens, Crystalline; Lipid Peroxidation; Lipid Peroxides; Liposomes; Male; Microscopy, Electron; Middle Aged; Ophthalmic Solutions; Rabbits; Tissue Culture Techniques; Young Adult | 2009 |
Ability of N-acetylcarnosine to protect lens crystallins from oxidation and oxidative damage by radical probe mass spectrometry (RP-MS).
Topics: Amino Acid Sequence; Animals; Antioxidants; Carnosine; Cattle; Crystallins; Electrophoresis, Polyacrylamide Gel; Molecular Sequence Data; Oxidative Stress; Peptide Fragments; Proteome; Proteomics; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Trypsin | 2010 |
Mitochondria induce oxidative stress, generation of reactive oxygen species and redox state unbalance of the eye lens leading to human cataract formation: disruption of redox lens organization by phospholipid hydroperoxides as a common basis for cataract
Topics: Aged; Aging; Animals; Antioxidants; Aqueous Humor; Carnosine; Cataract; Female; Humans; Hydrogen Peroxide; Lens, Crystalline; Lipid Peroxidation; Lipid Peroxides; Male; Mice; Mice, Inbred C57BL; Middle Aged; Mitochondria; Ophthalmic Solutions; Oxidation-Reduction; Oxidative Stress; Phospholipids; Prodrugs; Rabbits; Reactive Oxygen Species | 2011 |
Bioactivation antioxidant and transglycating properties of N-acetylcarnosine autoinduction prodrug of a dipeptide L-carnosine in mucoadhesive drug delivery eye-drop formulation: powerful eye health application technique and therapeutic platform.
Topics: Adhesiveness; Administration, Ophthalmic; Animals; Antioxidants; Biological Availability; Carnosine; Chemistry Techniques, Analytical; Clinical Trials as Topic; Drug Delivery Systems; Drug Design; Humans; Ophthalmic Solutions; Oxidation-Reduction; Prodrugs | 2012 |
Senescent phenotype of trabecular meshwork cells displays biomarkers in primary open-angle glaucoma.
Topics: Antioxidants; Aqueous Humor; Biomarkers; Carnosine; Cellular Senescence; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ophthalmic Solutions; Oxidative Stress; Phenotype; Trabecular Meshwork | 2011 |
Rapid formation and resolution of cataracts following orthopedic surgery for a patient with Charcot-Marie-Tooth disease.
Topics: Carnosine; Cataract; Charcot-Marie-Tooth Disease; Foot Deformities, Acquired; Humans; Male; Middle Aged; Orthopedic Procedures; Remission, Spontaneous; Self Medication | 2012 |
Dermal peptide delivery using enhancer molecules and colloidal carrier systems--part I: carnosine.
Topics: Administration, Cutaneous; Biological Availability; Carnosine; Chemistry, Pharmaceutical; Drug Delivery Systems; Emulsions; Excipients; Glycols; Humans; Hydrophobic and Hydrophilic Interactions; Organ Culture Techniques; Pentanes; Skin | 2012 |
Natural dipeptides as mini-chaperones: molecular mechanism of inhibition of lens βL-crystallin aggregation.
Topics: Animals; Anserine; beta-Crystallins; Carnosine; Cataract; Cattle; Dipeptides; Hydrophobic and Hydrophilic Interactions; Kinetics; Lens, Crystalline; Molecular Chaperones; Protein Carbonylation; Protein Conformation; Ultraviolet Rays | 2012 |
[Deceleration of cataract development in rats under the action of N-acetylcarnosine and D-pantethine mixture].
Topics: Animals; Carnosine; Cataract; Chromatography, Gel; Drug Combinations; Eye Proteins; Injections, Intraperitoneal; Lens, Crystalline; Male; Ophthalmic Solutions; Pantetheine; Protective Agents; Protein Aggregates; Radiation Injuries, Experimental; Rats; Rats, Wistar; Solubility; Ultraviolet Rays | 2014 |
An approach to revolutionize cataract treatment by enhancing drug probing through intraocular cell line.
Topics: Administration, Ophthalmic; Animals; Carnosine; Cataract; Cell Culture Techniques; Cell Line; Cornea; Delayed-Action Preparations; Drug Delivery Systems; Endothelial Cells; Goats; Humans; Nanoparticles; Ocular Absorption; Particle Size | 2018 |
Biosynthesis, characterization and cytotoxicity of gold nanoparticles and their loading with N-acetylcarnosine for cataract treatment.
Topics: Animals; Biocompatible Materials; Carnosine; Cataract; Cell Line; Cell Survival; Cucurbitaceae; Gold; Green Chemistry Technology; Metal Nanoparticles; Mice; Particle Size; Plant Bark; Plant Extracts; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction | 2018 |
Investigation of a new horizon antifungal activity with enhancing the antimicrobial efficacy of ciprofloxacin and its binary mixture via their encapsulation in nanoassemblies: in vitro and in vivo evaluation.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Animals; Anti-Bacterial Agents; Antifungal Agents; Candida albicans; Carnosine; Ciprofloxacin; Cross-Linking Reagents; Drug Liberation; Male; Nanostructures; Particle Size; Rats; Rats, Sprague-Dawley; Sheep | 2020 |
TGFβ2-Hepcidin Feed-Forward Loop in the Trabecular Meshwork Implicates Iron in Glaucomatous Pathology.
Topics: Adult; Aged; Aged, 80 and over; Animals; Blotting, Western; Carnosine; Cation Transport Proteins; Cattle; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Female; Ferritins; Glaucoma, Open-Angle; Heparin; Hepcidins; Humans; Immunohistochemistry; Iron; Male; Middle Aged; Organ Culture Techniques; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Tissue Donors; Trabecular Meshwork; Transforming Growth Factor beta2; Up-Regulation | 2020 |
Effectuation of loading a natural acetyl carnosine derivative within a promising cross-linked cyclodextrin spongey-like nanospheres on Physicochemical characterization and release behavior.
Topics: Calorimetry, Differential Scanning; Carnosine; Chemistry, Pharmaceutical; Cyclodextrins; Delayed-Action Preparations; Drug Carriers; Drug Liberation; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nanospheres; Polymers; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction | 2021 |