carnosine has been researched along with homocarnosine in 137 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 52 (37.96) | 18.7374 |
1990's | 32 (23.36) | 18.2507 |
2000's | 32 (23.36) | 29.6817 |
2010's | 16 (11.68) | 24.3611 |
2020's | 5 (3.65) | 2.80 |
Authors | Studies |
---|---|
Amorini, AM; Bellia, F; Di Pietro, V; Giardina, B; La Mendola, D; Lazzarino, G; Rizzarelli, E; Sortino, S; Tavazzi, B; Vecchio, G | 1 |
Hansen, S; Kish, SJ; Perry, TL | 1 |
Gjessing, LR; Kish, SJ; Løken, AC; Nesbakken, R; Perry, TL; Schrader, H; Sjaastad, O | 1 |
Bondarenko, TI; Makletsova, MG; Uskova, NI | 1 |
Ginsburg, I; Kohen, R; Misgav, R | 1 |
Drescher, DG; Drescher, MJ | 1 |
Ben-Menachem, E; Haegele, KD; Huebert, N; Mumford, J; Persson, LI | 1 |
Andreone, C; Artero, C; Biffo, S; Fasolo, A; Margolis, FL; Martì, E; Mulatero, B | 1 |
Dargie, HJ; MacFarlane, N; McMurray, J; Miller, DJ; O'Dowd, JJ | 1 |
Mendzheritskiĭ, AM; Povilaĭtite, PE; Uskova, NI | 1 |
Jackson, MC; Kucera, CM; Lenney, JF | 1 |
Gjessing, LR; Lenney, JF; Lunde, HA; Mørkrid, L; Sjaastad, O | 1 |
Cairns, MT; Miller, DJ; O'Dowd, JJ; Robins, DJ; Trainor, M | 1 |
Ben Menachem, E; Haegele, KD; Hardenberg, J; Huebert, N; Persson, L; Schechter, PJ | 1 |
Ben-Menachem, E; Dahlgren, L; Haegele, KD; Hardenberg, J; Huebert, N; Mumford, JP; Persson, LI; Schechter, PJ | 1 |
Halonen, T; Hartikainen, P; Kutvonen, R; Matilainen, R; Pitkänen, A; Riekkinen, P | 1 |
Aruoma, OI; Halliwell, B; Laughton, MJ | 1 |
Drukker, NA; Iurovskiĭ, SL; Madan, M; Orlov, VI; Pogorelova, TN | 1 |
Bondarenko, TI; Krichevskaia, AA; Papakina, IG | 1 |
Halonen, T; Pitkanen, A; Riekkinen, PJ; Sivenius, J; Ylinen, A | 1 |
Ferraro, TN; Hare, TA; Manyam, BV | 1 |
Agid, Y; Bonnet, AM; De Smet, Y; Grove, J; Saint-Hilaire, MH; Schechter, PJ; Tell, G | 1 |
Anderson, R; Mitchell, R | 1 |
Nagai, K; Suda, T | 2 |
Hansen, S; Perry, TL; Wall, RA | 1 |
Matilainen, R; Pitkänen, A; Riekkinen, P; Ruutiainen, T | 1 |
Ames, BN; Cundy, KC; Kohen, R; Yamamoto, Y | 1 |
Gaio, JM; Hommel, M; Perret, J; Pollak, P | 1 |
Gjessing, L; Halvorsen, S; Lenney, JF; Lunde, HA | 1 |
Haegele, KD; Schechter, PJ; Schmitt, AH; Schoun, J; Schwartz, JJ | 1 |
Gjessing, LR; Lunde, HA; Sjaastad, O | 1 |
Bondarenko, TI; Koshchiĭ, GN; Krichevskaia, AA | 1 |
Anderson, GH; Morris, P; Sheiner, JB | 1 |
Bondarenko, TI; Khodakova, AA; Mendzheritskaia, LG | 1 |
Brucher, JM; Casaer, P; Corbeel, L; de Cock, P; Eeckels, R; Eggermont, E; Jaeken, J; Schechter, PJ | 1 |
Bondarenko, TI; Makletsova, MG | 1 |
Agid, Y; Böhlen, P; Bonnet, AM; Chazot, G; Coquillat, G; Fischer, C; Koch-Weser, J; Schechter, PJ; Tell, G | 1 |
Dow, R; Fink, G; Grieve, G; Mitchell, R | 1 |
Grove, J; Palfreyman, MG; Schechter, PJ | 1 |
Ohtsuka, C; Sato, Y; Takahashi, H | 1 |
Agid, Y; Böhlen, P; Chazot, G; Coquillat, G; Fischer, C; Koch-Weser, J; Schechter, PJ; Tell, G | 1 |
Gauthier, SG; Hansen, S; Perry, TL; Wall, RA | 1 |
Børresen, AL; Gjessing, LR; Haugan, I; Hole, K; Sjaastad, O; Ziesler, O | 1 |
Kucera, CM; Lenney, JF; Peppers, SC; Sjaastad, O | 1 |
Bondarenko, TI; Makletsova, MG; Sukhomovskiĭ, BI | 1 |
Ohtsuka, C; Takahashi, H | 1 |
Grove, J; Koch-Weser, J; Marescaux, C; Rumbach, L; Schechter, PJ; Sjoerdsma, A; Tell, G; Warter, JM | 1 |
Grove, J; Huot, S; Palfreyman, MG | 1 |
Bauer, K; Hallermayer, K; Hamprecht, B; Kleinkauf, H; Salnikow, J | 1 |
Gjessing, L; Lunde, H; Sjaastad, O | 1 |
Palfreyman, MG; Robin, MM | 1 |
Chan, PW; George, RP; Kucera, CM; Lenney, JF; Rinzler, GS; Weiss, AM | 1 |
Grove, J; Koch-Weser, J; Marescaux, C; Rumbach, L; Schechter, PJ; Tell, G; Warter, JM | 1 |
Agid, Y; de Smet, Y; Grove, J; Hanke, NF; Koch-Weser, J; Schechter, PJ; Tell, G | 1 |
Takahashi, H | 2 |
Böhlen, P; Huot, S; Mellet, M; Palfreyman, MG | 1 |
Boldyrev, AA; Kurella, EG; Tiulina, OV | 1 |
Boldyrev, AA | 1 |
Dufy, B; Lorsignol, A; Taupignon, A | 1 |
Bozić, K; Filipović, D; Ivetić, V; Naumović, N; Nikolić, V | 1 |
Halonen, T; Kälviäinen, R; Pitkänen, A; Riekkinen, PJ | 1 |
Jackson, MC; Lenney, JF; Mack, RJ; Scollard, DM | 1 |
Datta, AK; Kasprzak, KS; Shi, X | 1 |
Gibson, KM; Jaeken, J; Jakobs, C | 1 |
Boldyrev, AA; Bulygina, ER; Kurella, EG; Tiulina, OV; Volynskaia, EA | 1 |
Mineeva, MF; Stvolinskiĭ, SL | 1 |
Lysenko, AV; Mendzheritskii, AM; Uskova, NI | 1 |
Boldyrev, AA; Carpenter, DO; Hori, N; Koshelev, VB; Stvolinsky, SL; Tyulina, OV | 1 |
Bonassi, S; De Biase, A; Deeva, IB; Degan, P; Doronin, YK; Iaccarino, M; Korkina, LG; Oral, R; Pagano, G; Warnau, M | 1 |
Behar, KL; Petroff, OA; Prichard, JW; Rothman, DL | 1 |
Abbott, JN; Himsworth, DT; Hipkiss, AR; Preston, JE; Romero, IA | 1 |
Hamajima, N; Wada, Y | 1 |
Behar, KL; Hyder, F; Mattson, RH; Petroff, OA; Rothman, DL | 1 |
Hyder, F; Mattson, RH; Petroff, OA; Rothman, DL | 5 |
Behar, KL; Charney, DS; Delaney, R; Hooten, M; Krystal, JH; Navarro, V; Petersen, KF; Petrakis, IL; Petroff, OA; Rothman, DL; Shulman, GI | 1 |
Collins, T; Hyder, F; Mattson, RH; Petroff, OA; Rothman, DL | 1 |
Choi, SY; Kang, JH; Kwon, HY; Kwon, OB | 1 |
Boldyrev, A; Carpenter, DO; Lawrence, D; Song, R | 1 |
Bonfanti, L; De Marchis, S; Fasolo, A; Luzzati, F; Peretto, P | 1 |
Boesiger, P; Duc, CO; Meier, D; Mueller, SG; Russ, W; Weber, B; Weber, OM; Wieser, HG | 1 |
Henry, TR; Theodore, WH | 1 |
Almai, A; Behar, KL; Charney, DS; Goddard, AW; Krystal, JH; Mason, GF; Petroff, OA; Rothman, DL | 1 |
Boldyrev, AA; Ivanova-Smolenskaya, IA; Kramarenko, GG; Markova, ED | 1 |
Baslow, MH; Berg, MJ; Bhakoo, KK; Marks, N; Saito, M; Suckow, RF | 1 |
Harada, Y; Hasegawa, Y; Sawamura, M; Ukeda, H | 1 |
Choi, SY; Kang, JH; Kang, TC; Kim, KS; Kwon, HY; Won, MH | 3 |
Kohen, R; Lazarovici, P; Tabakman, R | 1 |
Barker, GJ; Duncan, JS; McLean, MA; Simister, RJ | 3 |
ABRAHAM, D; PISANO, JJ; UDENFRIEND, S | 3 |
ABRAHAM, D; COHEN, L; PISANO, JJ; UDENFRIEND, S; WILSON, JD | 1 |
ANASTASI, A; ERSPAMER, V | 1 |
Aldini, G; Arlandini, E; Beretta, G; Carini, M; Facino, RM | 1 |
Behar, KL; de Graaf, RA; Patel, AB; Zhang, XM | 1 |
Jiang, H; Kohen, R; Lazarovici, P; Levine, RA; Tabakman, R | 1 |
Gibson, KM; Pearl, PL | 1 |
Chen, G; Chen, H; Chen, M; Duan, J; Huang, Y | 1 |
Gibson, KM; Jakobs, C; Jansen, EE; Shigematsu, Y; Verhoeven, NM | 1 |
Bauer, K | 1 |
Aldini, G; Beretta, G; Carini, M; Facino, RM | 1 |
Aldini, G; Cattaneo, M; Pedretti, A; Testa, B; Vistoli, G | 1 |
Chen, G; Duan, J; Huang, Y; Shi, Y | 1 |
Kang, JH; Kim, NH | 1 |
Kang, JH | 2 |
Arning, E; Bottiglieri, T; Gibson, KM; Hager, EJ; Homanics, GE; Jakobs, C; Jansen, EE; Paul, HS; Skvorak, KJ; Strom, SC; Sun, Q; Zinnanti, WJ | 1 |
Adelmann, K; Frey, D; Hoffmann, GF; Jakobs, C; Jansen, EW; Janssen, B; Kebbewar, M; Klingbeil, K; Koeppel, H; Mack, M; Peters, V; Riedl, E; Yard, BA; Zschocke, J | 1 |
Kang, JH; Lee, MS; Yoon, JH | 1 |
Campesi, I; Carru, C; Deiana, L; Franconi, F; Sotgia, S; Zinellu, A | 1 |
Brismar, K; Forsberg, E; Gross, ML; Peters, V; Schmitt, CP; Zschocke, J | 1 |
Adkins, DE; Batman, AM; Beardsley, PM; Clark, SL; Crowley, JJ; McClay, JL; Souza, RP; Sullivan, PF; van den Oord, EJ; Vann, RE; Vunck, SA | 1 |
Arena, G; Bellia, F; Grasso, GI; Rizzarelli, E; Vecchio, G | 1 |
Bellia, F; Rizzarelli, E; Vecchio, G | 1 |
Chevalier, N; Stroobant, V; Van Schaftingen, E; Veiga-da-Cunha, M; Vertommen, D | 1 |
Johnson, EJ; Kennedy, AD; Kuchan, MJ; Lai, CS; Lieblein-Boff, JC | 1 |
Carloni, P; De Vivo, M; Pavlin, M; Rossetti, G | 1 |
Aldini, G; Carini, M; Colzani, M; Grazioso, G; Maddis, DD; Mazzolari, A; Pedretti, A; Vistoli, G | 1 |
Fan, H; Fang, X; Huang, J; Liu, Q; Wang, T; Yi, G; Yi, X; Yu, D | 1 |
Tang, T; Wang, Y; Xia, D; Xia, Y; Xu, S; Zhang, H; Zhou, P | 1 |
Li, X; Wang, J; Wang, W; Yang, H; Zhang, Y; Zhu, Y; Zhu, Z | 1 |
Al-Iedani, O; Arm, J; Lea, R; Lechner-Scott, J; Ramadan, S | 1 |
Deelchand, DK; Henry, PG; Marjańska, M; Terpstra, M | 1 |
Aldini, G; Angeli, A; Dallanoce, C; Fumagalli, L; Supuran, CT; Vistoli, G | 1 |
Juchem, C; Landheer, K; Petroff, OA; Prinsen, H; Rothman, DL | 1 |
Arima, T; Egusa, A; Komaru, T; Kumrungsee, T; Oishi, Y; Sato, K; Sato, M; Yanaka, N | 1 |
Al-Iedani, O; Arm, J; Lea, R; Lechner-Scott, J; Ramadan, S; Ribbons, K | 1 |
6 review(s) available for carnosine and homocarnosine
Article | Year |
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[Carnosine metabolism in excitable tissues: biological significance].
Topics: Animals; Anserine; Antioxidants; Brain; Carnosine; Heart; Humans; Lipid Peroxidation; Muscles; Myocardium; Oxygen; Peroxidase; Superoxides; Thymine; Ultraviolet Rays | 1995 |
Inherited disorders of GABA metabolism.
Topics: 4-Aminobutyrate Transaminase; Aldehyde Oxidoreductases; Amino Acid Metabolism, Inborn Errors; Carnosine; Dipeptidases; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Succinate-Semialdehyde Dehydrogenase | 1993 |
[Serum carnosinase deficiency and homocarnosinosis].
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Carnosine; Diagnosis, Differential; Dipeptidases; Humans; Prognosis | 1998 |
Clinical aspects of the disorders of GABA metabolism in children.
Topics: 4-Aminobutyrate Transaminase; Aldehyde Oxidoreductases; Amino Acid Metabolism, Inborn Errors; Brain; Carnosine; Child; Developmental Disabilities; Diagnosis, Differential; Epilepsy; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Magnetic Resonance Imaging; Phenotype; Pyridoxal Phosphate; Pyridoxine; Succinate-Semialdehyde Dehydrogenase | 2004 |
Carnosine and homocarnosine, the forgotten, enigmatic peptides of the brain.
Topics: Animals; Biological Transport; Brain; Carnosine; Cells, Cultured; Female; Macrophages; Male; Molecular Structure; Neuroglia; Ovary; Peptides; Pituitary Gland, Anterior; Testis | 2005 |
Carnosinases, their substrates and diseases.
Topics: Carnosine; Dipeptidases; Dipeptides; Humans; Neoplasms; Nervous System Diseases; Protein Conformation; Structure-Activity Relationship; Substrate Specificity | 2014 |
5 trial(s) available for carnosine and homocarnosine
Article | Year |
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Treatment of Huntington disease with gamma-acetylenic GABA an irreversible inhibitor of GABA-transaminase: increased CSF GABA and homocarnosine without clinical amelioration.
Topics: 4-Aminobutyrate Transaminase; Adult; Aged; Alkynes; Aminocaproates; Brain; Brain Chemistry; Carnosine; Female; Humans; Huntington Disease; Male; Middle Aged; Seizures; Synaptic Transmission; Transaminases | 1981 |
Vigabatrin increases human brain homocarnosine and improves seizure control.
Topics: Adult; Anticonvulsants; Carnosine; Dose-Response Relationship, Drug; Epilepsy, Complex Partial; Female; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Occipital Lobe; Osmolar Concentration; Treatment Outcome; Vigabatrin | 1998 |
Effects of vigabatrin on brain GABA+/CR signals in patients with epilepsy monitored by 1H-NMR-spectroscopy: responder characteristics.
Topics: Adolescent; Adult; Anticonvulsants; Brain; Brain Chemistry; Carnosine; Creatine; Epilepsy; Epilepsy, Temporal Lobe; Female; Functional Laterality; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Occipital Lobe; Phosphocreatine; Treatment Outcome; Vigabatrin | 2001 |
Proton MRS reveals frontal lobe metabolite abnormalities in idiopathic generalized epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Aspartic Acid; Carnosine; Epilepsy, Generalized; Female; Frontal Lobe; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Protons; Reference Values; Valproic Acid | 2003 |
Proton MR spectroscopy of metabolite concentrations in temporal lobe epilepsy and effect of temporal lobe resection.
Topics: Adolescent; Adult; Aspartic Acid; Brain Chemistry; Brain Mapping; Carnosine; Creatine; Epilepsy, Temporal Lobe; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Protons; Young Adult | 2009 |
126 other study(ies) available for carnosine and homocarnosine
Article | Year |
---|---|
Synthesis and antioxidant activity of new homocarnosine beta-cyclodextrin conjugates.
Topics: Antioxidants; beta-Cyclodextrins; Carnosine; Hydrogen-Ion Concentration; Imidazoles; Lipoproteins, LDL; Magnetic Resonance Spectroscopy; Molecular Structure; Oxidation-Reduction | 2007 |
Regional distribution of homocarnosine, homocarnosine-carnosine synthetase and homocarnosinase in human brain.
Topics: Adult; Alanine; Brain; Brain Chemistry; Carnosine; Dipeptidases; Dipeptides; gamma-Aminobutyric Acid; Humans; Kinetics; Peptide Synthases; Substrate Specificity; Tissue Distribution | 1979 |
Homocarnosinosis: increased content of homocarnosine and deficiency of homocarnosinase in brain.
Topics: Adult; Brain; Carnosine; Dipeptidases; Dipeptides; Epilepsy; Female; gamma-Aminobutyric Acid; Histidine; Humans; Lysine; Middle Aged | 1979 |
[Use of gamma-aminobutyric acid from various sources in the synthesis of homocarnosine in the brain of animals of various ages].
Topics: Aging; Animals; Brain; Carbon Radioisotopes; Carnosine; gamma-Aminobutyric Acid; Putrescine; Rats | 1992 |
The SOD like activity of copper:carnosine, copper:anserine and copper:homocarnosine complexes.
Topics: Anserine; Antioxidants; Carnosine; Copper; Copper Sulfate; Free Radical Scavengers; Free Radicals; Humans; Neutrophils; Streptococcus; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate | 1991 |
N-acetylhistidine, glutamate, and beta-alanine are concentrated in a receptor cell layer of the trout inner ear.
Topics: Animals; beta-Alanine; Carnosine; Chromatography, High Pressure Liquid; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hair Cells, Auditory; Histidine; Saccule and Utricle; Trout | 1991 |
Effect of long-term vigabatrin therapy on selected neurotransmitter concentrations in cerebrospinal fluid.
Topics: Adult; Aminocaproates; Anticonvulsants; Carnosine; Electroencephalography; Epilepsy, Complex Partial; Female; gamma-Aminobutyric Acid; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Long-Term Care; Male; Methoxyhydroxyphenylglycol; Middle Aged; Vigabatrin | 1991 |
Carnosine in the brain and olfactory system of amphibia and reptilia: a comparative study using immunocytochemical and biochemical methods.
Topics: Animals; Brain Chemistry; Carnosine; Female; Glial Fibrillary Acidic Protein; Lizards; Male; Neuroglia; Neurons; Olfactory Bulb; Rana esculenta; Species Specificity; Xenopus laevis | 1991 |
Synergism of histidyl dipeptides as antioxidants.
Topics: Anserine; Antioxidants; Carnosine; Drug Synergism; Free Radicals; Histidine; Methylhistidines; Oxidation-Reduction | 1991 |
[Brain gamma-aminobutyric acid and homocarnosine in stress].
Topics: Animals; Brain; Brain Chemistry; Carnosine; Delta Sleep-Inducing Peptide; gamma-Aminobutyric Acid; Hyperbaric Oxygenation; Piracetam; Rats; Restraint, Physical; Stress, Physiological | 1991 |
Purification and properties of human serum carnosinase.
Topics: Age Factors; Amino Acid Sequence; Animals; Anserine; Brain; Carnosine; Chromatography, DEAE-Cellulose; Cricetinae; Dipeptidases; Electrophoresis, Polyacrylamide Gel; Female; Glycoproteins; Haplorhini; Humans; Isoelectric Focusing; Male; Mesocricetus; Molecular Sequence Data; Muscles; Species Specificity | 1991 |
Inborn errors of carnosine and homocarnosine metabolism.
Topics: Adult; Aged; Carnosine; Dipeptides; Female; gamma-Aminobutyric Acid; Humans; Male; Metabolism, Inborn Errors; Middle Aged | 1990 |
Analysis of carnosine, homocarnosine, and other histidyl derivatives in rat brain.
Topics: Acetylation; Amino Acids; Animals; Brain Chemistry; Carnosine; Chromatography, High Pressure Liquid; Dipeptides; Histidine; Magnetic Resonance Spectroscopy; Male; Molecular Structure; Rats; Rats, Inbred Strains | 1990 |
Cerebrospinal fluid parameters in healthy volunteers during serial lumbar punctures.
Topics: Adult; Albumins; Carnosine; Cerebrospinal Fluid Proteins; Dipeptides; Female; gamma-Aminobutyric Acid; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Immunoglobulin G; Male; Reference Values; Spinal Puncture | 1989 |
The effect of different vigabatrin treatment regimens on CSF biochemistry and seizure control in epileptic patients.
Topics: Adult; Aminocaproates; Anticonvulsants; Carnosine; Cerebrospinal Fluid Proteins; Epilepsy; Female; gamma-Aminobutyric Acid; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Vigabatrin | 1989 |
Inhibitory and excitatory amino acids in cerebrospinal fluid of chronic epileptic patients.
Topics: Adolescent; Adult; Amino Acids; Aspartic Acid; Carnosine; Dipeptides; Epilepsies, Partial; Epilepsy; Female; Glutamine; Humans; Male | 1989 |
Carnosine, homocarnosine and anserine: could they act as antioxidants in vivo?
Topics: alpha 1-Antitrypsin; Animals; Anserine; Antioxidants; Carnosine; Dipeptides; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Hypoxanthine; Hypoxanthines; Kinetics; Lipid Peroxidation; Liposomes; Microsomes, Liver; Pancreatic Elastase; Rats; Superoxides; Xanthine Oxidase | 1989 |
[Homocarnosine of the amniotic fluid as an indicator of fetal cerebral lesions].
Topics: Amniotic Fluid; Brain Diseases, Metabolic; Carnosine; Dipeptides; Female; Fetal Diseases; Humans; Hypothalamic Diseases; Maternal-Fetal Exchange; Pregnancy; Pregnancy Complications; Pregnancy in Diabetics; Prenatal Diagnosis; Thyroid Diseases | 1989 |
[The effect of the delta-sleep peptide on the homocarnosine content of the brain in rats under the action of cold stress].
Topics: Animals; Brain; Brain Chemistry; Carnosine; Cold Temperature; Delta Sleep-Inducing Peptide; Dipeptides; Dose-Response Relationship, Drug; Drug Interactions; Male; Rats; Stress, Physiological; Time Factors | 1989 |
Cerebrospinal fluid GABA and seizure control with vigabatrin.
Topics: Adolescent; Adult; Aminocaproates; Anticonvulsants; Carnosine; Female; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Seizures; Vigabatrin | 1989 |
Evaluation of amino acid neurotransmitters, related compounds, and precursors in dystonia.
Topics: Adult; Amino Acids; Analysis of Variance; Carnosine; Dystonia; Ethanolamine; Ethanolamines; gamma-Aminobutyric Acid; Glutamine; Humans; Neurotransmitter Agents | 1988 |
Cerebrospinal fluid GABA and homocarnosine concentrations in patients with Friedreich's ataxia, Parkinson's disease, and Huntington's chorea.
Topics: Adult; Aged; Carnosine; Dipeptides; Female; Friedreich Ataxia; gamma-Aminobutyric Acid; Humans; Huntington Disease; Levodopa; Male; Middle Aged; Parkinson Disease | 1987 |
Biphasic effect of GABAA receptor agonists on prolactin secretion: evidence for two types of GABAA receptor complex on lactotrophes.
Topics: Animals; Baclofen; Carnosine; Isonicotinic Acids; Male; Muscimol; Prolactin; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1986 |
[Immunoregulative effects of homocarnosine and gamma-aminobuthyric acid].
Topics: Aging; Animals; Antibody Formation; Carnosine; Dipeptides; gamma-Aminobutyric Acid; Homeostasis; Immunity; Immunity, Cellular; Mice; Mitomycin; Mitomycins; Wound Healing | 1986 |
Brain amino compounds in a Huntington's disease patient on isoniazid therapy.
Topics: Adult; Brain Chemistry; Carnosine; Caudate Nucleus; Cerebellar Nuclei; gamma-Aminobutyric Acid; Humans; Huntington Disease; Isoniazid; Male; Putamen; Substantia Nigra | 1985 |
Levels of total gamma-aminobutyric acid (GABA), free GABA and homocarnosine in cerebrospinal fluid of epileptic patients before and during gamma-vinyl-GABA (vigabatrin) treatment.
Topics: Adolescent; Adult; Aminocaproates; Carnosine; Dipeptides; Dose-Response Relationship, Drug; Epilepsy; Female; gamma-Aminobutyric Acid; Humans; Male; Vigabatrin | 1988 |
Antioxidant activity of carnosine, homocarnosine, and anserine present in muscle and brain.
Topics: Amidines; Anserine; Antioxidants; Azo Compounds; Brain; Carnosine; Chromatography, High Pressure Liquid; Deoxyguanosine; Dipeptides; Electrochemistry; Free Radicals; Histidine; Lipid Peroxides; Muscles; Nitriles; Solutions; Structure-Activity Relationship | 1988 |
Clinical and biochemical effects of gamma-vinyl Gaba in tardive dyskinesia.
Topics: Aged; Aminocaproates; Carnosine; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Humans; Mental Disorders; Vigabatrin | 1987 |
Serum carnosinase in blood and homocarnosine in CSF of patients with Følling's disease (PKU).
Topics: Adolescent; Carnosine; Child; Dipeptidases; Dipeptides; Female; Humans; Infant, Newborn; Male; Middle Aged; Phenylalanine; Phenylketonurias | 1987 |
2-Pyrrolidinone in human cerebrospinal fluid: a major constituent of total gamma-aminobutyric acid.
Topics: Adult; Carnosine; Female; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Humans; Mass Spectrometry; Middle Aged; Pyrrolidinones | 1987 |
Homocarnosinosis: influence of dietary restriction of histidine.
Topics: Adult; Amino Acids; Carnosine; Diet; Dipeptides; Histidine; Humans; Male; Metabolism, Inborn Errors | 1986 |
[Immuno-enhancing actions of carnosine and homocarnosine].
Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Carnosine; Dipeptides; gamma-Aminobutyric Acid; Immunity; Male; Mice | 1986 |
[Homocarnosine in the brain of rats during cold adaptation].
Topics: Adaptation, Physiological; Animals; Atmosphere Exposure Chambers; Brain; Carnosine; Cold Temperature; Dipeptides; Female; Male; Rats; Stress, Physiological; Time Factors | 1985 |
Food intake suppression by histidine.
Topics: Animals; Brain Chemistry; Carnosine; Circadian Rhythm; Depression, Chemical; Eating; Feeding Behavior; Histidine; Male; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence | 1985 |
[Age and the role of certain mediators in the sensitivity of animals to hyperbaric oxygenation].
Topics: Age Factors; Animals; Brain Chemistry; Carnosine; Dipeptides; gamma-Aminobutyric Acid; Histamine; Histidine; Hyperbaric Oxygenation; Neurotransmitter Agents; Rabbits; Rats | 1980 |
Gamma-aminobutyric acid-transaminase deficiency: a newly recognized inborn error of neurotransmitter metabolism.
Topics: 4-Aminobutyrate Transaminase; beta-Alanine; Brain; Carnosine; Diffuse Cerebral Sclerosis of Schilder; Female; gamma-Aminobutyric Acid; Gigantism; Humans; Infant; Infant, Newborn; Male; Metabolism, Inborn Errors; Neurotransmitter Agents | 1984 |
[Quantitative assay of homocarnosine in cerebrospinal fluid and blood].
Topics: Carnosine; Central Nervous System Diseases; Child; Child, Preschool; Dipeptides; Humans; Infant; Methods | 1982 |
Endogenous GABA receptor ligands in hypophysial portal blood.
Topics: 4-Aminobutyrate Transaminase; Animals; Brain; Carnosine; Electric Stimulation; gamma-Aminobutyric Acid; Male; Pituitary Gland; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Cerebrospinal fluid GABA as an index of brain GABA activity.
Topics: Adult; Aged; Brain; Carnosine; gamma-Aminobutyric Acid; Humans; Middle Aged; Synaptic Transmission | 1983 |
Homocarnosine levels in cerebrospinal fluid of patients with infantile spasms under ACTH therapy.
Topics: Adrenocorticotropic Hormone; Carnosine; Dipeptides; Humans; Infant; Spasms, Infantile | 1983 |
Cerebrospinal fluid homocarnosine in Huntington's disease.
Topics: Adult; Aged; Carnosine; Chromatography, Ion Exchange; Dipeptides; Female; Humans; Huntington Disease; Male; Middle Aged; Spectrometry, Fluorescence | 1980 |
Human CSF GABA concentrations: revised downward for controls, but not decreased in Huntington's chorea.
Topics: Carbon Radioisotopes; Carnosine; gamma-Aminobutyric Acid; Humans; Huntington Disease; Reference Values | 1982 |
Transport and distribution of homocarnosine after intracerebroventricular and intravenous injection in the rat.
Topics: Animals; Biological Transport; Brain; Carnosine; Chromatography, High Pressure Liquid; Dipeptides; gamma-Aminobutyric Acid; Injections, Intravenous; Injections, Intraventricular; Male; Rats; Synaptosomes; Tissue Distribution | 1984 |
Homocarnosinosis: lack of serum carnosinase is the defect probably responsible for elevated brain and CSF homocarnosine.
Topics: Adult; Brain; Carnosine; Cerebral Cortex; Dipeptidases; Dipeptides; Female; Humans; Kidney; Male; Middle Aged | 1983 |
[Concentration of free amino acids and homocarnosine dipeptide in the cerebrospinal fluid of children with hydrocephalus].
Topics: Amino Acids; Carnosine; Cerebral Ventricles; Child, Preschool; Dipeptides; gamma-Aminobutyric Acid; Humans; Hydrocephalus; Infant; Intellectual Disability; Meningitis; Subarachnoid Space | 1983 |
Brain function estimated from the ratio of glutamine to homocarnosine levels in cerebrospinal fluid.
Topics: Bacterial Infections; Carnosine; Child; Child, Preschool; Dipeptides; Epilepsy; Female; Glutamine; Humans; Infant; Infant, Newborn; Leukemia; Male; Meningeal Neoplasms; Meningitis; Meningitis, Viral; Seizures, Febrile | 1983 |
Increased gamma-aminobutyric acid (GABA), homocarnosine and beta-alanine in cerebrospinal fluid of patients treated with gamma-vinyl GABA (4-amino-hex-5-enoic acid).
Topics: 4-Aminobutyrate Transaminase; Adult; Aged; Alanine; Aminocaproates; beta-Alanine; Carnosine; Chromatography, Ion Exchange; Dipeptides; Female; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Spectrometry, Fluorescence; Vigabatrin | 1981 |
Total GABA and homocarnosine in CSF as indices of brain GABA concentrations.
Topics: Aminocaproates; Animals; Brain; Carnosine; Dipeptides; gamma-Aminobutyric Acid; Male; Rats; Rats, Inbred Strains; Vigabatrin | 1983 |
Biosynthesis of carnosine and related peptides by glial cells in primary culture.
Topics: Alanine; Animals; Animals, Newborn; Brain; Carnosine; Cells, Cultured; Dipeptides; gamma-Aminobutyric Acid; Kinetics; Mice; Neuroglia | 1982 |
Homocarnosinosis: hypercarnosinuria.
Topics: Adult; Aged; Anserine; Carnosine; Diet; Dipeptidases; Dipeptides; Female; Histidine; Humans; Male; Methylhistidines; Middle Aged; Poultry Products | 1982 |
Does homocarnosine mediate the dyskinetic movements induced by gaba-transaminase inhibitors.
Topics: 4-Aminobutyrate Transaminase; Animals; Bicuculline; Carnosine; Dipeptides; Dyskinesia, Drug-Induced; Injections, Intraventricular; Picrotoxin; Rats | 1982 |
Human serum carnosinase: characterization, distinction from cellular carnosinase, and activation by cadmium.
Topics: Adolescent; Adult; Aged; Aging; Cadmium; Carnosine; Child; Child, Preschool; Dipeptidases; Enzyme Activation; Humans; Infant; Isoelectric Point; Isoenzymes; Kinetics; Middle Aged; Molecular Weight; Substrate Specificity | 1982 |
Artifactual increases in the concentration of free GABA in samples of human cerebrospinal fluid are due to degradation of homocarnosine.
Topics: Carnosine; Dipeptides; False Positive Reactions; gamma-Aminobutyric Acid; Humans; Time Factors | 1982 |
Concentration gradients of free and total gamma-aminobutyric acid and homocarnosine in human CSF: comparison of suboccipital and lumbar sampling.
Topics: Adult; Aged; Carnosine; Dipeptides; Female; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Spinal Puncture | 1982 |
Studies on homocarnosine in cerebrospinal fluid in infancy and childhood. Part I. Homocarnosine level in cerebrospinal fluid of normal infants and children.
Topics: Aging; Carnosine; Child; Child, Preschool; Dipeptides; Female; Humans; Infant; Infant, Newborn; Male | 1981 |
Studies on homocarnosine in cerebrospinal fluid in infancy and childhood. Part II. Homocarnosine levels in cerebrospinal fluid from children with epilepsy, febrile convulsion or meningitis.
Topics: Adolescent; Carnosine; Child; Child, Preschool; Consciousness Disorders; Dipeptides; Epilepsy; Female; Humans; Infant; Infant, Newborn; Male; Meningitis; Seizures, Febrile | 1981 |
The effect of gamma-vinyl GABA and gamma-acetylenic GABA on the concentration of homocarnosine in brain and CSF of the rat.
Topics: Alkynes; Aminocaproates; Animals; Brain; Carnosine; Chromatography, Ion Exchange; Dose-Response Relationship, Drug; Male; Rats; Vigabatrin | 1980 |
[Oxidative stability of Na,K-ATPase].
Topics: Adenosine Triphosphate; Animals; Carnosine; Cattle; Dogs; Enzyme Stability; Hydrogen Peroxide; Hydrolysis; Hypochlorous Acid; Kinetics; Oxidants; Oxidation-Reduction; Oxygen; Sodium-Potassium-Exchanging ATPase; Temperature | 1995 |
Short applications of gamma-aminobutyric acid increase intracellular calcium concentrations in single identified rat lactotrophs.
Topics: Animals; Calcium; Calcium Channel Blockers; Carnosine; Clonazepam; Female; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Immunohistochemistry; Ion Channel Gating; Membrane Potentials; Muscimol; Patch-Clamp Techniques; Pituitary Gland, Anterior; Radioimmunoassay; Rats; Rats, Wistar; Receptors, GABA-A | 1994 |
[The effect of homocarnosine on neuronal activity during satiation and starvation].
Topics: Action Potentials; Animals; Carnosine; Caudate Nucleus; Hippocampus; Neurons; Rabbits; Satiation; Starvation | 1993 |
Amino acid levels in the cerebrospinal fluid of newly diagnosed epileptic patients: effect of vigabatrin and carbamazepine monotherapies.
Topics: Adolescent; Adult; Amino Acids; Aminocaproates; Carbamazepine; Carnosine; Epilepsy; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Humans; Male; Middle Aged; Vigabatrin | 1993 |
Localization of a novel pathway for the liberation of GABA in the human CNS.
Topics: Animals; Antibody Specificity; Carnosine; Central Nervous System; Dipeptidases; gamma-Aminobutyric Acid; Humans; Immunoenzyme Techniques; Immunohistochemistry; Mice; Mice, Inbred BALB C | 1994 |
Effect of carnosine homocarnosine and anserine on hydroxylation of the guanine moiety in 2'-deoxyguanosine, DNA and nucleohistone with hydrogen peroxide in the presence of nickel(II).
Topics: Anserine; Carnosine; Deoxyguanosine; DNA; Electron Spin Resonance Spectroscopy; Guanine; Histones; Hydrogen Peroxide; Hydroxylation; Nickel; Oxidation-Reduction | 1993 |
[The effect of hydrogen peroxide and hypochlorite on brain Na,K-ATPase activity].
Topics: Animals; Antioxidants; Brain; Butylated Hydroxytoluene; Carnosine; Cattle; Deferoxamine; Hydrogen Peroxide; Hypochlorous Acid; Sodium-Potassium-Exchanging ATPase; Vitamin E | 1995 |
[Effect of histidine-containing dipeptides on brain tyrosine hydroxylase].
Topics: Animals; Anserine; Antioxidants; Brain; Carnosine; Histidine; Kinetics; Rats; Substrate Specificity; Tyrosine 3-Monooxygenase | 1996 |
[Comparative investigation of anticonvulsive effects of putrescine and structural analogues of delta-sleep-inducing peptide].
Topics: Animals; Brain; Carnosine; Delta Sleep-Inducing Peptide; gamma-Aminobutyric Acid; Hyperbaric Oxygenation; Lipid Peroxidation; Male; Putrescine; Rats; Seizures | 1996 |
Biochemical and physiological evidence that carnosine is an endogenous neuroprotector against free radicals.
Topics: Animals; Anserine; Brain; Brain Ischemia; Carnosine; Cattle; Free Radicals; Hippocampus; Hydrogen Peroxide; Hypoxia; In Vitro Techniques; Kinetics; Neuroprotective Agents; Pressure; Rats; Respiration; Sodium-Potassium-Exchanging ATPase; Tyrosine 3-Monooxygenase | 1997 |
L-methionine induces stage-dependent changes of differentiation and oxidative activity in sea urchin embryogenesis.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Anserine; Antioxidants; Carnosine; Chromosome Aberrations; Deoxyguanosine; Embryo, Nonmammalian; Free Radical Scavengers; Germ Cells; Luminescent Measurements; Methionine; Mitosis; Reactive Oxygen Species; Sea Urchins; Stereoisomerism | 1997 |
Homocarnosine and the measurement of neuronal pH in patients with epilepsy.
Topics: Adult; Anticonvulsants; Brain Chemistry; Carnosine; Epilepsy; Female; gamma-Aminobutyric Acid; Humans; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurons; Vigabatrin | 1997 |
Toxic effects of beta-amyloid(25-35) on immortalised rat brain endothelial cell: protection by carnosine, homocarnosine and beta-alanine.
Topics: Amyloid beta-Peptides; Animals; beta-Alanine; Carnosine; Cell Line, Transformed; Endothelium, Vascular; Enzyme Inhibitors; Guanidines; L-Lactate Dehydrogenase; Neuroprotective Agents; Peptide Fragments; Rats; Superoxide Dismutase | 1998 |
Topiramate increases brain GABA, homocarnosine, and pyrrolidinone in patients with epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Brain; Carnosine; Epilepsy; Female; Fructose; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Pyrrolidinones; Topiramate | 1999 |
Preliminary evidence of low cortical GABA levels in localized 1H-MR spectra of alcohol-dependent and hepatic encephalopathy patients.
Topics: Adult; Age of Onset; Alcoholism; Carnosine; Cerebral Cortex; gamma-Aminobutyric Acid; Hepatic Encephalopathy; Humans; Magnetic Resonance Spectroscopy; Middle Aged; Protons; Radionuclide Imaging | 1999 |
Acute effects of vigabatrin on brain GABA and homocarnosine in patients with complex partial seizures.
Topics: Administration, Oral; Adult; Anticonvulsants; Brain; Brain Chemistry; Carnosine; Dose-Response Relationship, Drug; Drug Administration Schedule; Epilepsy, Complex Partial; Female; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Occipital Lobe; Vigabatrin | 1999 |
Hydrogen peroxide-mediated Cu,Zn-superoxide dismutase fragmentation: protection by carnosine, homocarnosine and anserine.
Topics: Anserine; Carnosine; Electrophoresis, Polyacrylamide Gel; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Pentetic Acid; Superoxide Dismutase | 1999 |
Carnosine protects against excitotoxic cell death independently of effects on reactive oxygen species.
Topics: Animals; Apoptosis; Carnosine; Cells, Cultured; Kainic Acid; Kinetics; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Rats; Rats, Wistar; Reactive Oxygen Species | 1999 |
Effects of gabapentin on brain GABA, homocarnosine, and pyrrolidinone in epilepsy patients.
Topics: Acetates; Adult; Amines; Anticonvulsants; Brain Chemistry; Carnosine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Occipital Lobe; Pyrrolidinones | 2000 |
Aminoacyl-histidine dipeptides in the glial cells of the adult rabbit forebrain.
Topics: Animals; Brain; Carnosine; Cell Division; Cell Movement; Glial Fibrillary Acidic Protein; Histidine; Immunohistochemistry; Neural Cell Adhesion Molecules; Neuroglia; Peptides; Rabbits; Rats; Rats, Wistar | 2000 |
Homocarnosine elevations: a cause or a sign of seizure control?
Topics: Carnosine; Epilepsy; Humans; Magnetic Resonance Spectroscopy | 2001 |
Homocarnosine and seizure control in juvenile myoclonic epilepsy and complex partial seizures.
Topics: Adult; Aged; Carnosine; Epilepsy, Complex Partial; Female; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Myoclonic Epilepsy, Juvenile; Time Factors | 2001 |
Reductions in occipital cortex GABA levels in panic disorder detected with 1h-magnetic resonance spectroscopy.
Topics: Adult; Agoraphobia; Ambulatory Care; Carnosine; Female; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Spectroscopy; Male; Occipital Lobe; Panic Disorder | 2001 |
Topiramate rapidly raises brain GABA in epilepsy patients.
Topics: Administration, Oral; Anticonvulsants; Brain Chemistry; Carnosine; Dose-Response Relationship, Drug; Drug Administration Schedule; Epilepsy, Complex Partial; Fructose; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Occipital Lobe; Pyrrolidinones; Stimulation, Chemical; Topiramate | 2001 |
Peculiarities of carnosine metabolism in a patient with pronounced homocarnosinemia.
Topics: Adolescent; Anserine; Carnosine; Chromatography, High Pressure Liquid; Dipeptidases; Dose-Response Relationship, Drug; Female; Humans; Male; Syndrome | 2001 |
Differential expression of carnosine, homocarnosine and N-acetyl-L-histidine hydrolytic activities in cultured rat macroglial cells.
Topics: Amidohydrolases; Animals; Brain; Carnosine; Cells, Cultured; Chromatography, High Pressure Liquid; Histidine; Hydrolysis; Neuroglia; Neurons; Oligodendroglia; Rats | 2001 |
Effect of carnosine and related compounds on the inactivation of human Cu,Zn-superoxide dismutase by modification of fructose and glycolaldehyde.
Topics: Acetaldehyde; Anserine; Carnosine; Dipeptides; Enzyme Activation; Free Radical Scavengers; Fructose; Histidine; Humans; Hydroxyl Radical; Superoxide Dismutase | 2002 |
Protection by carnosine-related dipeptides against hydrogen peroxide-mediated ceruloplasmin modification.
Topics: Animals; Anserine; Antioxidants; Carnosine; Ceruloplasmin; Copper; Humans; Hydrogen Peroxide; Hydroxyl Radical; In Vitro Techniques; Oxidation-Reduction; Peptide Fragments | 2002 |
Protective effects of carnosine, homocarnosine and anserine against peroxyl radical-mediated Cu,Zn-superoxide dismutase modification.
Topics: Amidines; Anserine; Carnosine; Catalase; Chelating Agents; Free Radical Scavengers; Free Radicals; Hydrogen-Ion Concentration; Oxidants; Oxidation-Reduction; Peroxides; Superoxide Dismutase; Time Factors | 2002 |
Neuroprotective effects of carnosine and homocarnosine on pheochromocytoma PC12 cells exposed to ischemia.
Topics: Animals; Carnosine; Cell Death; Dinoprostone; Ischemia; Neuroprotective Agents; PC12 Cells; Radioimmunoassay; Rats | 2002 |
Carnosine and related dipeptides protect human ceruloplasmin against peroxyl radical-mediated modification.
Topics: Anserine; Antioxidants; Carnosine; Ceruloplasmin; Dipeptides; Drug Antagonism; Humans; Peroxides | 2002 |
A proton magnetic resonance spectroscopy study of metabolites in the occipital lobes in epilepsy.
Topics: Adolescent; Adult; Aspartic Acid; Carnosine; Epilepsies, Partial; Epilepsy, Generalized; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Image Enhancement; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neural Inhibition; Occipital Lobe; Synaptic Transmission | 2003 |
Synthesis of homocarnosine in muscle in vivo.
Topics: Biochemical Phenomena; Carnosine; Muscles; Peptides | 1961 |
Isolation of gamma-aminobutyrylhistidine (homocarnosine) from brain.
Topics: Brain; Brain Chemistry; Carnosine; Humans; Peptides | 1961 |
The distribution of homocarnosine in mammals.
Topics: Animals; Brain; Carnosine; Humans; Mammals; Peptides | 1962 |
UPTAKE OF CARNOSINE AND HOMOCARNOSINE BY RAT BRAIN SLICES.
Topics: Amino Acids; Brain; Carbon Isotopes; Carnosine; Dipeptides; Histidine; Metabolism; Peptides; Rats; Research; Sarcoma; Sarcoma, Experimental; Tissue Culture Techniques | 1964 |
OCCURRENCE OF HOMOCARNOSINE (GAMMA-AMINOBUTYRYLHISTIDINE) IN THE BRAIN OF RANA ESCULENTA.
Topics: Animals; Anura; Brain; Brain Chemistry; Carnosine; Imidazoles; Rana esculenta; Research | 1964 |
Acrolein-sequestering ability of endogenous dipeptides: characterization of carnosine and homocarnosine/acrolein adducts by electrospray ionization tandem mass spectrometry.
Topics: Acrolein; Alzheimer Disease; Carnosine; Cytotoxins; Molecular Structure; Spectrometry, Mass, Electrospray Ionization | 2003 |
Determination of liposomal encapsulation efficiency using proton NMR spectroscopy.
Topics: Carnosine; Deuterium; Hydrogen-Ion Concentration; Liposomes; Magnetic Resonance Spectroscopy; Organometallic Compounds; Organophosphorus Compounds; Phospholipids; Protons | 2004 |
Apoptotic characteristics of cell death and the neuroprotective effect of homocarnosine on pheochromocytoma PC12 cells exposed to ischemia.
Topics: Animals; Apoptosis; Carnosine; Cell Death; Cell Hypoxia; Neuroprotective Agents; PC12 Cells; Phosphorylation; Rats | 2004 |
Separation and determination of carnosine-related peptides using capillary electrophoresis with laser-induced fluorescence detection.
Topics: Adolescent; Adult; Animals; Anserine; Benzoates; Carnosine; Cerebrospinal Fluid; Electrophoresis, Capillary; Humans; Lasers; Meat; Middle Aged; Muscles; Peptides; Quinolines; Sheep; Spectrometry, Fluorescence; Sus scrofa | 2005 |
A novel, quantitative assay for homocarnosine in cerebrospinal fluid using stable-isotope dilution liquid chromatography-tandem mass spectrometry.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Carnosine; Child; Child, Preschool; Chromatography, High Pressure Liquid; Deuterium; Female; gamma-Aminobutyric Acid; Humans; Infant; Male; Mass Spectrometry; Middle Aged; Radioisotope Dilution Technique; Reference Standards; Reference Values; Reproducibility of Results | 2006 |
Carnosine and related dipeptides as quenchers of reactive carbonyl species: from structural studies to therapeutic perspectives.
Topics: Acrolein; Aldehydes; Animals; Anserine; Carnosine; Chromatography, Liquid; Dipeptides; Histidine; Muscle, Skeletal; Oxidation-Reduction; Rats; Spectrometry, Mass, Electrospray Ionization | 2005 |
Brain homocarnosine and seizure control of patients taking gabapentin or topiramate.
Topics: Adult; Amines; Anticonvulsants; Brain Chemistry; Carnosine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsy, Complex Partial; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neocortex; Topiramate; Treatment Outcome; Visual Cortex | 2006 |
Homology modeling of human serum carnosinase, a potential medicinal target, and MD simulations of its allosteric activation by citrate.
Topics: Allosteric Regulation; Amidohydrolases; Anions; Anserine; Carnosine; Catalytic Domain; Citric Acid; Computer Simulation; Dipeptidases; Enzyme Activation; Humans; Models, Molecular; Protein Binding; Protein Conformation; Sequence Homology, Amino Acid; Serum | 2006 |
Field-amplified on-line sample stacking for determination of carnosine-related peptides by capillary electrophoresis.
Topics: Anserine; Carnosine; Electrophoresis, Capillary; Reproducibility of Results; Sensitivity and Specificity; Solvents | 2006 |
Protective effects of histidine dipeptides on the modification of neurofilament-L by the cytochrome c/hydrogen peroxide system.
Topics: Animals; Anserine; Antioxidants; Carnosine; Cytochromes c; Dipeptides; Histidine; Hydrogen Peroxide; Mice; Neurofilament Proteins; Oxidation-Reduction; Protective Agents; Tyrosine | 2007 |
Ferritin enhances salsolinol-mediated DNA strand breakage: protection by carnosine and related compounds.
Topics: Anserine; Carnosine; Catalase; DNA Breaks, Single-Stranded; DNA, Superhelical; Escherichia coli; Ferritins; Ferrozine; Free Radical Scavengers; Hydroxides; Iron Chelating Agents; Isoquinolines; Lac Operon; Mutation; Oxidative Stress; Superoxide Dismutase; Time Factors | 2009 |
Hepatocyte transplantation (HTx) corrects selected neurometabolic abnormalities in murine intermediate maple syrup urine disease (iMSUD).
Topics: Animals; Brain; Carnosine; gamma-Aminobutyric Acid; Hepatocytes; Humans; Liver; Maple Syrup Urine Disease; Mice; Models, Biological; Neurotransmitter Agents | 2009 |
Relevance of allosteric conformations and homocarnosine concentration on carnosinase activity.
Topics: Adult; Allosteric Regulation; Animals; Blotting, Western; Carnosine; Child; Dipeptidases; Female; Humans; Male; Mice; Mice, Inbred BALB C; Middle Aged; Reference Values | 2010 |
Reaction of ferritin with hydrogen peroxide induces lipid peroxidation.
Topics: Anserine; Azides; Carnosine; Deferoxamine; Ferritins; Free Radical Scavengers; Hydrogen Peroxide; Iron Chelating Agents; Lipid Peroxidation; Thiourea | 2010 |
Protective effects of carnosine and homocarnosine on ferritin and hydrogen peroxide-mediated DNA damage.
Topics: Antioxidants; Carnosine; DNA Damage; Ferritins; Hydrogen Peroxide; Hydroxyl Radical; In Vitro Techniques; Lac Operon; Mutagenesis; Mutagenicity Tests; Oxidation-Reduction; Plasmids | 2010 |
Measurement of carnosine, homocarnosine and anserine by FASI capillary electrophoresis UV detection: applications on biological samples.
Topics: Anserine; Carnosine; Electrophoresis, Capillary; Spectrophotometry, Ultraviolet | 2011 |
Carnosine treatment largely prevents alterations of renal carnosine metabolism in diabetic mice.
Topics: Age Factors; Animals; Animals, Genetically Modified; Anserine; Capillary Permeability; Carnosine; Diabetes Mellitus; Diabetic Nephropathies; Dipeptidases; Disease Models, Animal; Humans; Kidney; Mice; Proteinuria | 2012 |
Behavioral metabolomics analysis identifies novel neurochemical signatures in methamphetamine sensitization.
Topics: Animals; Brain; Butyrates; Carnosine; Central Nervous System Sensitization; Guanidines; Inositol; Male; Metabolome; Methamphetamine; Mice; Mice, Inbred C57BL; Pantothenic Acid | 2013 |
Copper(II)-chelating homocarnosine glycoconjugate as a new multifunctional compound.
Topics: Amyloid beta-Peptides; Carnosine; Chelating Agents; Circular Dichroism; Coordination Complexes; Copper; Drug Stability; Electron Spin Resonance Spectroscopy; Glycoconjugates; Magnetic Resonance Spectroscopy; Spectrophotometry, Ultraviolet; Superoxide Dismutase; Trehalose | 2014 |
Metabolite proofreading in carnosine and homocarnosine synthesis: molecular identification of PM20D2 as β-alanyl-lysine dipeptidase.
Topics: Animals; Carnosine; Dipeptidases; Dipeptides; HEK293 Cells; Humans; Mass Spectrometry; Mice; Organ Specificity; Peptide Synthases; Rats; Recombinant Proteins; Substrate Specificity | 2014 |
Exploratory Metabolomic Analyses Reveal Compounds Correlated with Lutein Concentration in Frontal Cortex, Hippocampus, and Occipital Cortex of Human Infant Brain.
Topics: Carnosine; Dietary Supplements; Energy Metabolism; Female; Frontal Lobe; Hippocampus; Humans; Infant; Infant, Newborn; Lipid Metabolism; Lutein; Male; Metabolomics; Occipital Lobe | 2015 |
Carnosine and Homocarnosine Degradation Mechanisms by the Human Carnosinase Enzyme CN1: Insights from Multiscale Simulations.
Topics: Carnosine; Catalytic Domain; Dipeptidases; Humans; Hydrogen Bonding; Molecular Dynamics Simulation; Zinc | 2016 |
Computational approaches in the rational design of improved carbonyl quenchers: focus on histidine containing dipeptides.
Topics: Animals; Anserine; Carnosine; Computer Simulation; Dipeptides; Drug Design; Histidine; Humans; Stereoisomerism | 2016 |
l-Homocarnosine attenuates inflammation in cerebral ischemia-reperfusion injury through inhibition of nod-like receptor protein 3 inflammasome.
Topics: Animals; Apoptosis; Carnosine; Catalase; Dietary Supplements; Gene Expression Regulation; Humans; Infarction, Middle Cerebral Artery; Inflammasomes; Inflammation; Interleukin-6; Lipid Peroxidation; Microscopy, Fluorescence; NLR Family, Pyrin Domain-Containing 3 Protein; Rats; Reperfusion Injury; Tumor Necrosis Factor-alpha | 2018 |
Synergistic effect of vancomycin and l-homocarnosine alleviates Staphylococcus aureus-induced osteomyelitis in rats.
Topics: Animals; Anti-Bacterial Agents; Carnosine; Drug Synergism; Drug Therapy, Combination; Male; Osteomyelitis; Rats; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 2019 |
[Determination of anserine, homocarnosine and carnosine in meat products by ion chromatography with integrated pulsed amperometric detection].
Topics: Animals; Anserine; Carnosine; Chromatography, Ion Exchange; Ducks; Food Contamination; Geese; Meat Products | 2018 |
Diurnal variability of cerebral metabolites in healthy human brain with 2D localized correlation spectroscopy (2D L-COSY).
Topics: Adult; Aspartic Acid; Brain; Carnosine; Choline; Circadian Rhythm; Creatine; Cross-Over Studies; Female; Fucose; Glutathione; Healthy Volunteers; Humans; Inositol; Lipid Metabolism; Magnetic Resonance Spectroscopy; Male; Middle Aged; Reference Values; Reproducibility of Results; Young Adult | 2019 |
MEGA-PRESS of GABA+: Influences of acquisition parameters.
Topics: Carnosine; Computer Simulation; gamma-Aminobutyric Acid; Humans; Macromolecular Substances; Magnetic Resonance Spectroscopy | 2021 |
Activation Effects of Carnosine- and Histidine-Containing Dipeptides on Human Carbonic Anhydrases: A Comprehensive Study.
Topics: Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase IX; Carbonic Anhydrase V; Carbonic Anhydrases; Carnosine; Chelating Agents; Dipeptides; Histidine; Humans; Kinetics; Models, Molecular; Protein Domains; Protons; Software | 2020 |
Elevated homocarnosine and GABA in subject on isoniazid as assessed through 1H MRS at 7T.
Topics: Adult; Brain Chemistry; Carnosine; Female; gamma-Aminobutyric Acid; Healthy Volunteers; Humans; Isoniazid; Magnetic Resonance Spectroscopy; Male; Middle Aged; Young Adult | 2020 |
Dietary GABA induces endogenous synthesis of a novel imidazole peptide homocarnosine in mouse skeletal muscles.
Topics: Animals; beta-Alanine; Carnosine; Diet; Feeding Behavior; GABA Agents; gamma-Aminobutyric Acid; Imidazoles; Male; Mice; Mice, Inbred ICR; Muscle, Skeletal | 2020 |
Biochemical Correlations with Fatigue in Multiple Sclerosis Detected by MR 2D Localized Correlated Spectroscopy.
Topics: Adult; Aspartic Acid; Carnosine; Choline; Creatine; Fatigue; Female; Glutathione; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Young Adult | 2021 |