Page last updated: 2024-08-21

carnosine and homocarnosine

carnosine has been researched along with homocarnosine in 137 studies

Research

Studies (137)

TimeframeStudies, this research(%)All Research%
pre-199052 (37.96)18.7374
1990's32 (23.36)18.2507
2000's32 (23.36)29.6817
2010's16 (11.68)24.3611
2020's5 (3.65)2.80

Authors

AuthorsStudies
Amorini, AM; Bellia, F; Di Pietro, V; Giardina, B; La Mendola, D; Lazzarino, G; Rizzarelli, E; Sortino, S; Tavazzi, B; Vecchio, G1
Hansen, S; Kish, SJ; Perry, TL1
Gjessing, LR; Kish, SJ; Løken, AC; Nesbakken, R; Perry, TL; Schrader, H; Sjaastad, O1
Bondarenko, TI; Makletsova, MG; Uskova, NI1
Ginsburg, I; Kohen, R; Misgav, R1
Drescher, DG; Drescher, MJ1
Ben-Menachem, E; Haegele, KD; Huebert, N; Mumford, J; Persson, LI1
Andreone, C; Artero, C; Biffo, S; Fasolo, A; Margolis, FL; Martì, E; Mulatero, B1
Dargie, HJ; MacFarlane, N; McMurray, J; Miller, DJ; O'Dowd, JJ1
Mendzheritskiĭ, AM; Povilaĭtite, PE; Uskova, NI1
Jackson, MC; Kucera, CM; Lenney, JF1
Gjessing, LR; Lenney, JF; Lunde, HA; Mørkrid, L; Sjaastad, O1
Cairns, MT; Miller, DJ; O'Dowd, JJ; Robins, DJ; Trainor, M1
Ben Menachem, E; Haegele, KD; Hardenberg, J; Huebert, N; Persson, L; Schechter, PJ1
Ben-Menachem, E; Dahlgren, L; Haegele, KD; Hardenberg, J; Huebert, N; Mumford, JP; Persson, LI; Schechter, PJ1
Halonen, T; Hartikainen, P; Kutvonen, R; Matilainen, R; Pitkänen, A; Riekkinen, P1
Aruoma, OI; Halliwell, B; Laughton, MJ1
Drukker, NA; Iurovskiĭ, SL; Madan, M; Orlov, VI; Pogorelova, TN1
Bondarenko, TI; Krichevskaia, AA; Papakina, IG1
Halonen, T; Pitkanen, A; Riekkinen, PJ; Sivenius, J; Ylinen, A1
Ferraro, TN; Hare, TA; Manyam, BV1
Agid, Y; Bonnet, AM; De Smet, Y; Grove, J; Saint-Hilaire, MH; Schechter, PJ; Tell, G1
Anderson, R; Mitchell, R1
Nagai, K; Suda, T2
Hansen, S; Perry, TL; Wall, RA1
Matilainen, R; Pitkänen, A; Riekkinen, P; Ruutiainen, T1
Ames, BN; Cundy, KC; Kohen, R; Yamamoto, Y1
Gaio, JM; Hommel, M; Perret, J; Pollak, P1
Gjessing, L; Halvorsen, S; Lenney, JF; Lunde, HA1
Haegele, KD; Schechter, PJ; Schmitt, AH; Schoun, J; Schwartz, JJ1
Gjessing, LR; Lunde, HA; Sjaastad, O1
Bondarenko, TI; Koshchiĭ, GN; Krichevskaia, AA1
Anderson, GH; Morris, P; Sheiner, JB1
Bondarenko, TI; Khodakova, AA; Mendzheritskaia, LG1
Brucher, JM; Casaer, P; Corbeel, L; de Cock, P; Eeckels, R; Eggermont, E; Jaeken, J; Schechter, PJ1
Bondarenko, TI; Makletsova, MG1
Agid, Y; Böhlen, P; Bonnet, AM; Chazot, G; Coquillat, G; Fischer, C; Koch-Weser, J; Schechter, PJ; Tell, G1
Dow, R; Fink, G; Grieve, G; Mitchell, R1
Grove, J; Palfreyman, MG; Schechter, PJ1
Ohtsuka, C; Sato, Y; Takahashi, H1
Agid, Y; Böhlen, P; Chazot, G; Coquillat, G; Fischer, C; Koch-Weser, J; Schechter, PJ; Tell, G1
Gauthier, SG; Hansen, S; Perry, TL; Wall, RA1
Børresen, AL; Gjessing, LR; Haugan, I; Hole, K; Sjaastad, O; Ziesler, O1
Kucera, CM; Lenney, JF; Peppers, SC; Sjaastad, O1
Bondarenko, TI; Makletsova, MG; Sukhomovskiĭ, BI1
Ohtsuka, C; Takahashi, H1
Grove, J; Koch-Weser, J; Marescaux, C; Rumbach, L; Schechter, PJ; Sjoerdsma, A; Tell, G; Warter, JM1
Grove, J; Huot, S; Palfreyman, MG1
Bauer, K; Hallermayer, K; Hamprecht, B; Kleinkauf, H; Salnikow, J1
Gjessing, L; Lunde, H; Sjaastad, O1
Palfreyman, MG; Robin, MM1
Chan, PW; George, RP; Kucera, CM; Lenney, JF; Rinzler, GS; Weiss, AM1
Grove, J; Koch-Weser, J; Marescaux, C; Rumbach, L; Schechter, PJ; Tell, G; Warter, JM1
Agid, Y; de Smet, Y; Grove, J; Hanke, NF; Koch-Weser, J; Schechter, PJ; Tell, G1
Takahashi, H2
Böhlen, P; Huot, S; Mellet, M; Palfreyman, MG1
Boldyrev, AA; Kurella, EG; Tiulina, OV1
Boldyrev, AA1
Dufy, B; Lorsignol, A; Taupignon, A1
Bozić, K; Filipović, D; Ivetić, V; Naumović, N; Nikolić, V1
Halonen, T; Kälviäinen, R; Pitkänen, A; Riekkinen, PJ1
Jackson, MC; Lenney, JF; Mack, RJ; Scollard, DM1
Datta, AK; Kasprzak, KS; Shi, X1
Gibson, KM; Jaeken, J; Jakobs, C1
Boldyrev, AA; Bulygina, ER; Kurella, EG; Tiulina, OV; Volynskaia, EA1
Mineeva, MF; Stvolinskiĭ, SL1
Lysenko, AV; Mendzheritskii, AM; Uskova, NI1
Boldyrev, AA; Carpenter, DO; Hori, N; Koshelev, VB; Stvolinsky, SL; Tyulina, OV1
Bonassi, S; De Biase, A; Deeva, IB; Degan, P; Doronin, YK; Iaccarino, M; Korkina, LG; Oral, R; Pagano, G; Warnau, M1
Behar, KL; Petroff, OA; Prichard, JW; Rothman, DL1
Abbott, JN; Himsworth, DT; Hipkiss, AR; Preston, JE; Romero, IA1
Hamajima, N; Wada, Y1
Behar, KL; Hyder, F; Mattson, RH; Petroff, OA; Rothman, DL1
Hyder, F; Mattson, RH; Petroff, OA; Rothman, DL5
Behar, KL; Charney, DS; Delaney, R; Hooten, M; Krystal, JH; Navarro, V; Petersen, KF; Petrakis, IL; Petroff, OA; Rothman, DL; Shulman, GI1
Collins, T; Hyder, F; Mattson, RH; Petroff, OA; Rothman, DL1
Choi, SY; Kang, JH; Kwon, HY; Kwon, OB1
Boldyrev, A; Carpenter, DO; Lawrence, D; Song, R1
Bonfanti, L; De Marchis, S; Fasolo, A; Luzzati, F; Peretto, P1
Boesiger, P; Duc, CO; Meier, D; Mueller, SG; Russ, W; Weber, B; Weber, OM; Wieser, HG1
Henry, TR; Theodore, WH1
Almai, A; Behar, KL; Charney, DS; Goddard, AW; Krystal, JH; Mason, GF; Petroff, OA; Rothman, DL1
Boldyrev, AA; Ivanova-Smolenskaya, IA; Kramarenko, GG; Markova, ED1
Baslow, MH; Berg, MJ; Bhakoo, KK; Marks, N; Saito, M; Suckow, RF1
Harada, Y; Hasegawa, Y; Sawamura, M; Ukeda, H1
Choi, SY; Kang, JH; Kang, TC; Kim, KS; Kwon, HY; Won, MH3
Kohen, R; Lazarovici, P; Tabakman, R1
Barker, GJ; Duncan, JS; McLean, MA; Simister, RJ3
ABRAHAM, D; PISANO, JJ; UDENFRIEND, S3
ABRAHAM, D; COHEN, L; PISANO, JJ; UDENFRIEND, S; WILSON, JD1
ANASTASI, A; ERSPAMER, V1
Aldini, G; Arlandini, E; Beretta, G; Carini, M; Facino, RM1
Behar, KL; de Graaf, RA; Patel, AB; Zhang, XM1
Jiang, H; Kohen, R; Lazarovici, P; Levine, RA; Tabakman, R1
Gibson, KM; Pearl, PL1
Chen, G; Chen, H; Chen, M; Duan, J; Huang, Y1
Gibson, KM; Jakobs, C; Jansen, EE; Shigematsu, Y; Verhoeven, NM1
Bauer, K1
Aldini, G; Beretta, G; Carini, M; Facino, RM1
Aldini, G; Cattaneo, M; Pedretti, A; Testa, B; Vistoli, G1
Chen, G; Duan, J; Huang, Y; Shi, Y1
Kang, JH; Kim, NH1
Kang, JH2
Arning, E; Bottiglieri, T; Gibson, KM; Hager, EJ; Homanics, GE; Jakobs, C; Jansen, EE; Paul, HS; Skvorak, KJ; Strom, SC; Sun, Q; Zinnanti, WJ1
Adelmann, K; Frey, D; Hoffmann, GF; Jakobs, C; Jansen, EW; Janssen, B; Kebbewar, M; Klingbeil, K; Koeppel, H; Mack, M; Peters, V; Riedl, E; Yard, BA; Zschocke, J1
Kang, JH; Lee, MS; Yoon, JH1
Campesi, I; Carru, C; Deiana, L; Franconi, F; Sotgia, S; Zinellu, A1
Brismar, K; Forsberg, E; Gross, ML; Peters, V; Schmitt, CP; Zschocke, J1
Adkins, DE; Batman, AM; Beardsley, PM; Clark, SL; Crowley, JJ; McClay, JL; Souza, RP; Sullivan, PF; van den Oord, EJ; Vann, RE; Vunck, SA1
Arena, G; Bellia, F; Grasso, GI; Rizzarelli, E; Vecchio, G1
Bellia, F; Rizzarelli, E; Vecchio, G1
Chevalier, N; Stroobant, V; Van Schaftingen, E; Veiga-da-Cunha, M; Vertommen, D1
Johnson, EJ; Kennedy, AD; Kuchan, MJ; Lai, CS; Lieblein-Boff, JC1
Carloni, P; De Vivo, M; Pavlin, M; Rossetti, G1
Aldini, G; Carini, M; Colzani, M; Grazioso, G; Maddis, DD; Mazzolari, A; Pedretti, A; Vistoli, G1
Fan, H; Fang, X; Huang, J; Liu, Q; Wang, T; Yi, G; Yi, X; Yu, D1
Tang, T; Wang, Y; Xia, D; Xia, Y; Xu, S; Zhang, H; Zhou, P1
Li, X; Wang, J; Wang, W; Yang, H; Zhang, Y; Zhu, Y; Zhu, Z1
Al-Iedani, O; Arm, J; Lea, R; Lechner-Scott, J; Ramadan, S1
Deelchand, DK; Henry, PG; Marjańska, M; Terpstra, M1
Aldini, G; Angeli, A; Dallanoce, C; Fumagalli, L; Supuran, CT; Vistoli, G1
Juchem, C; Landheer, K; Petroff, OA; Prinsen, H; Rothman, DL1
Arima, T; Egusa, A; Komaru, T; Kumrungsee, T; Oishi, Y; Sato, K; Sato, M; Yanaka, N1
Al-Iedani, O; Arm, J; Lea, R; Lechner-Scott, J; Ramadan, S; Ribbons, K1

Reviews

6 review(s) available for carnosine and homocarnosine

ArticleYear
[Carnosine metabolism in excitable tissues: biological significance].
    Vestnik Rossiiskoi akademii meditsinskikh nauk, 1995, Issue:6

    Topics: Animals; Anserine; Antioxidants; Brain; Carnosine; Heart; Humans; Lipid Peroxidation; Muscles; Myocardium; Oxygen; Peroxidase; Superoxides; Thymine; Ultraviolet Rays

1995
Inherited disorders of GABA metabolism.
    Journal of inherited metabolic disease, 1993, Volume: 16, Issue:4

    Topics: 4-Aminobutyrate Transaminase; Aldehyde Oxidoreductases; Amino Acid Metabolism, Inborn Errors; Carnosine; Dipeptidases; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Succinate-Semialdehyde Dehydrogenase

1993
[Serum carnosinase deficiency and homocarnosinosis].
    Ryoikibetsu shokogun shirizu, 1998, Issue:18 Pt 1

    Topics: Amino Acid Metabolism, Inborn Errors; Animals; Carnosine; Diagnosis, Differential; Dipeptidases; Humans; Prognosis

1998
Clinical aspects of the disorders of GABA metabolism in children.
    Current opinion in neurology, 2004, Volume: 17, Issue:2

    Topics: 4-Aminobutyrate Transaminase; Aldehyde Oxidoreductases; Amino Acid Metabolism, Inborn Errors; Brain; Carnosine; Child; Developmental Disabilities; Diagnosis, Differential; Epilepsy; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Magnetic Resonance Imaging; Phenotype; Pyridoxal Phosphate; Pyridoxine; Succinate-Semialdehyde Dehydrogenase

2004
Carnosine and homocarnosine, the forgotten, enigmatic peptides of the brain.
    Neurochemical research, 2005, Volume: 30, Issue:10

    Topics: Animals; Biological Transport; Brain; Carnosine; Cells, Cultured; Female; Macrophages; Male; Molecular Structure; Neuroglia; Ovary; Peptides; Pituitary Gland, Anterior; Testis

2005
Carnosinases, their substrates and diseases.
    Molecules (Basel, Switzerland), 2014, Feb-21, Volume: 19, Issue:2

    Topics: Carnosine; Dipeptidases; Dipeptides; Humans; Neoplasms; Nervous System Diseases; Protein Conformation; Structure-Activity Relationship; Substrate Specificity

2014

Trials

5 trial(s) available for carnosine and homocarnosine

ArticleYear
Treatment of Huntington disease with gamma-acetylenic GABA an irreversible inhibitor of GABA-transaminase: increased CSF GABA and homocarnosine without clinical amelioration.
    Neurology, 1981, Volume: 31, Issue:2

    Topics: 4-Aminobutyrate Transaminase; Adult; Aged; Alkynes; Aminocaproates; Brain; Brain Chemistry; Carnosine; Female; Humans; Huntington Disease; Male; Middle Aged; Seizures; Synaptic Transmission; Transaminases

1981
Vigabatrin increases human brain homocarnosine and improves seizure control.
    Annals of neurology, 1998, Volume: 44, Issue:6

    Topics: Adult; Anticonvulsants; Carnosine; Dose-Response Relationship, Drug; Epilepsy, Complex Partial; Female; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Occipital Lobe; Osmolar Concentration; Treatment Outcome; Vigabatrin

1998
Effects of vigabatrin on brain GABA+/CR signals in patients with epilepsy monitored by 1H-NMR-spectroscopy: responder characteristics.
    Epilepsia, 2001, Volume: 42, Issue:1

    Topics: Adolescent; Adult; Anticonvulsants; Brain; Brain Chemistry; Carnosine; Creatine; Epilepsy; Epilepsy, Temporal Lobe; Female; Functional Laterality; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Occipital Lobe; Phosphocreatine; Treatment Outcome; Vigabatrin

2001
Proton MRS reveals frontal lobe metabolite abnormalities in idiopathic generalized epilepsy.
    Neurology, 2003, Oct-14, Volume: 61, Issue:7

    Topics: Adolescent; Adult; Anticonvulsants; Aspartic Acid; Carnosine; Epilepsy, Generalized; Female; Frontal Lobe; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Protons; Reference Values; Valproic Acid

2003
Proton MR spectroscopy of metabolite concentrations in temporal lobe epilepsy and effect of temporal lobe resection.
    Epilepsy research, 2009, Volume: 83, Issue:2-3

    Topics: Adolescent; Adult; Aspartic Acid; Brain Chemistry; Brain Mapping; Carnosine; Creatine; Epilepsy, Temporal Lobe; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Protons; Young Adult

2009

Other Studies

126 other study(ies) available for carnosine and homocarnosine

ArticleYear
Synthesis and antioxidant activity of new homocarnosine beta-cyclodextrin conjugates.
    European journal of medicinal chemistry, 2007, Volume: 42, Issue:7

    Topics: Antioxidants; beta-Cyclodextrins; Carnosine; Hydrogen-Ion Concentration; Imidazoles; Lipoproteins, LDL; Magnetic Resonance Spectroscopy; Molecular Structure; Oxidation-Reduction

2007
Regional distribution of homocarnosine, homocarnosine-carnosine synthetase and homocarnosinase in human brain.
    Journal of neurochemistry, 1979, Volume: 32, Issue:6

    Topics: Adult; Alanine; Brain; Brain Chemistry; Carnosine; Dipeptidases; Dipeptides; gamma-Aminobutyric Acid; Humans; Kinetics; Peptide Synthases; Substrate Specificity; Tissue Distribution

1979
Homocarnosinosis: increased content of homocarnosine and deficiency of homocarnosinase in brain.
    Journal of neurochemistry, 1979, Volume: 32, Issue:6

    Topics: Adult; Brain; Carnosine; Dipeptidases; Dipeptides; Epilepsy; Female; gamma-Aminobutyric Acid; Histidine; Humans; Lysine; Middle Aged

1979
[Use of gamma-aminobutyric acid from various sources in the synthesis of homocarnosine in the brain of animals of various ages].
    Biokhimiia (Moscow, Russia), 1992, Volume: 57, Issue:9

    Topics: Aging; Animals; Brain; Carbon Radioisotopes; Carnosine; gamma-Aminobutyric Acid; Putrescine; Rats

1992
The SOD like activity of copper:carnosine, copper:anserine and copper:homocarnosine complexes.
    Free radical research communications, 1991, Volume: 12-13 Pt 1

    Topics: Anserine; Antioxidants; Carnosine; Copper; Copper Sulfate; Free Radical Scavengers; Free Radicals; Humans; Neutrophils; Streptococcus; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate

1991
N-acetylhistidine, glutamate, and beta-alanine are concentrated in a receptor cell layer of the trout inner ear.
    Journal of neurochemistry, 1991, Volume: 56, Issue:2

    Topics: Animals; beta-Alanine; Carnosine; Chromatography, High Pressure Liquid; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hair Cells, Auditory; Histidine; Saccule and Utricle; Trout

1991
Effect of long-term vigabatrin therapy on selected neurotransmitter concentrations in cerebrospinal fluid.
    Journal of child neurology, 1991, Volume: Suppl 2

    Topics: Adult; Aminocaproates; Anticonvulsants; Carnosine; Electroencephalography; Epilepsy, Complex Partial; Female; gamma-Aminobutyric Acid; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Long-Term Care; Male; Methoxyhydroxyphenylglycol; Middle Aged; Vigabatrin

1991
Carnosine in the brain and olfactory system of amphibia and reptilia: a comparative study using immunocytochemical and biochemical methods.
    Neuroscience letters, 1991, Sep-16, Volume: 130, Issue:2

    Topics: Animals; Brain Chemistry; Carnosine; Female; Glial Fibrillary Acidic Protein; Lizards; Male; Neuroglia; Neurons; Olfactory Bulb; Rana esculenta; Species Specificity; Xenopus laevis

1991
Synergism of histidyl dipeptides as antioxidants.
    Journal of molecular and cellular cardiology, 1991, Volume: 23, Issue:11

    Topics: Anserine; Antioxidants; Carnosine; Drug Synergism; Free Radicals; Histidine; Methylhistidines; Oxidation-Reduction

1991
[Brain gamma-aminobutyric acid and homocarnosine in stress].
    Nervnaia sistema, 1991, Volume: 30

    Topics: Animals; Brain; Brain Chemistry; Carnosine; Delta Sleep-Inducing Peptide; gamma-Aminobutyric Acid; Hyperbaric Oxygenation; Piracetam; Rats; Restraint, Physical; Stress, Physiological

1991
Purification and properties of human serum carnosinase.
    Clinica chimica acta; international journal of clinical chemistry, 1991, Feb-15, Volume: 196, Issue:2-3

    Topics: Age Factors; Amino Acid Sequence; Animals; Anserine; Brain; Carnosine; Chromatography, DEAE-Cellulose; Cricetinae; Dipeptidases; Electrophoresis, Polyacrylamide Gel; Female; Glycoproteins; Haplorhini; Humans; Isoelectric Focusing; Male; Mesocricetus; Molecular Sequence Data; Muscles; Species Specificity

1991
Inborn errors of carnosine and homocarnosine metabolism.
    Journal of neural transmission. Supplementum, 1990, Volume: 29

    Topics: Adult; Aged; Carnosine; Dipeptides; Female; gamma-Aminobutyric Acid; Humans; Male; Metabolism, Inborn Errors; Middle Aged

1990
Analysis of carnosine, homocarnosine, and other histidyl derivatives in rat brain.
    Journal of neurochemistry, 1990, Volume: 55, Issue:2

    Topics: Acetylation; Amino Acids; Animals; Brain Chemistry; Carnosine; Chromatography, High Pressure Liquid; Dipeptides; Histidine; Magnetic Resonance Spectroscopy; Male; Molecular Structure; Rats; Rats, Inbred Strains

1990
Cerebrospinal fluid parameters in healthy volunteers during serial lumbar punctures.
    Journal of neurochemistry, 1989, Volume: 52, Issue:2

    Topics: Adult; Albumins; Carnosine; Cerebrospinal Fluid Proteins; Dipeptides; Female; gamma-Aminobutyric Acid; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Immunoglobulin G; Male; Reference Values; Spinal Puncture

1989
The effect of different vigabatrin treatment regimens on CSF biochemistry and seizure control in epileptic patients.
    British journal of clinical pharmacology, 1989, Volume: 27 Suppl 1

    Topics: Adult; Aminocaproates; Anticonvulsants; Carnosine; Cerebrospinal Fluid Proteins; Epilepsy; Female; gamma-Aminobutyric Acid; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Vigabatrin

1989
Inhibitory and excitatory amino acids in cerebrospinal fluid of chronic epileptic patients.
    Journal of neural transmission, 1989, Volume: 76, Issue:3

    Topics: Adolescent; Adult; Amino Acids; Aspartic Acid; Carnosine; Dipeptides; Epilepsies, Partial; Epilepsy; Female; Glutamine; Humans; Male

1989
Carnosine, homocarnosine and anserine: could they act as antioxidants in vivo?
    The Biochemical journal, 1989, Dec-15, Volume: 264, Issue:3

    Topics: alpha 1-Antitrypsin; Animals; Anserine; Antioxidants; Carnosine; Dipeptides; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Hypoxanthine; Hypoxanthines; Kinetics; Lipid Peroxidation; Liposomes; Microsomes, Liver; Pancreatic Elastase; Rats; Superoxides; Xanthine Oxidase

1989
[Homocarnosine of the amniotic fluid as an indicator of fetal cerebral lesions].
    Akusherstvo i ginekologiia, 1989, Issue:9

    Topics: Amniotic Fluid; Brain Diseases, Metabolic; Carnosine; Dipeptides; Female; Fetal Diseases; Humans; Hypothalamic Diseases; Maternal-Fetal Exchange; Pregnancy; Pregnancy Complications; Pregnancy in Diabetics; Prenatal Diagnosis; Thyroid Diseases

1989
[The effect of the delta-sleep peptide on the homocarnosine content of the brain in rats under the action of cold stress].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1989, Volume: 75, Issue:12

    Topics: Animals; Brain; Brain Chemistry; Carnosine; Cold Temperature; Delta Sleep-Inducing Peptide; Dipeptides; Dose-Response Relationship, Drug; Drug Interactions; Male; Rats; Stress, Physiological; Time Factors

1989
Cerebrospinal fluid GABA and seizure control with vigabatrin.
    British journal of clinical pharmacology, 1989, Volume: 27 Suppl 1

    Topics: Adolescent; Adult; Aminocaproates; Anticonvulsants; Carnosine; Female; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Seizures; Vigabatrin

1989
Evaluation of amino acid neurotransmitters, related compounds, and precursors in dystonia.
    Advances in neurology, 1988, Volume: 50

    Topics: Adult; Amino Acids; Analysis of Variance; Carnosine; Dystonia; Ethanolamine; Ethanolamines; gamma-Aminobutyric Acid; Glutamine; Humans; Neurotransmitter Agents

1988
Cerebrospinal fluid GABA and homocarnosine concentrations in patients with Friedreich's ataxia, Parkinson's disease, and Huntington's chorea.
    Movement disorders : official journal of the Movement Disorder Society, 1987, Volume: 2, Issue:2

    Topics: Adult; Aged; Carnosine; Dipeptides; Female; Friedreich Ataxia; gamma-Aminobutyric Acid; Humans; Huntington Disease; Levodopa; Male; Middle Aged; Parkinson Disease

1987
Biphasic effect of GABAA receptor agonists on prolactin secretion: evidence for two types of GABAA receptor complex on lactotrophes.
    European journal of pharmacology, 1986, May-13, Volume: 124, Issue:1-2

    Topics: Animals; Baclofen; Carnosine; Isonicotinic Acids; Male; Muscimol; Prolactin; Rats; Rats, Inbred Strains; Receptors, GABA-A

1986
[Immunoregulative effects of homocarnosine and gamma-aminobuthyric acid].
    Nihon seirigaku zasshi. Journal of the Physiological Society of Japan, 1986, Volume: 48, Issue:6

    Topics: Aging; Animals; Antibody Formation; Carnosine; Dipeptides; gamma-Aminobutyric Acid; Homeostasis; Immunity; Immunity, Cellular; Mice; Mitomycin; Mitomycins; Wound Healing

1986
Brain amino compounds in a Huntington's disease patient on isoniazid therapy.
    Neurology, 1985, Volume: 35, Issue:5

    Topics: Adult; Brain Chemistry; Carnosine; Caudate Nucleus; Cerebellar Nuclei; gamma-Aminobutyric Acid; Humans; Huntington Disease; Isoniazid; Male; Putamen; Substantia Nigra

1985
Levels of total gamma-aminobutyric acid (GABA), free GABA and homocarnosine in cerebrospinal fluid of epileptic patients before and during gamma-vinyl-GABA (vigabatrin) treatment.
    Journal of the neurological sciences, 1988, Volume: 88, Issue:1-3

    Topics: Adolescent; Adult; Aminocaproates; Carnosine; Dipeptides; Dose-Response Relationship, Drug; Epilepsy; Female; gamma-Aminobutyric Acid; Humans; Male; Vigabatrin

1988
Antioxidant activity of carnosine, homocarnosine, and anserine present in muscle and brain.
    Proceedings of the National Academy of Sciences of the United States of America, 1988, Volume: 85, Issue:9

    Topics: Amidines; Anserine; Antioxidants; Azo Compounds; Brain; Carnosine; Chromatography, High Pressure Liquid; Deoxyguanosine; Dipeptides; Electrochemistry; Free Radicals; Histidine; Lipid Peroxides; Muscles; Nitriles; Solutions; Structure-Activity Relationship

1988
Clinical and biochemical effects of gamma-vinyl Gaba in tardive dyskinesia.
    Journal of neurology, neurosurgery, and psychiatry, 1987, Volume: 50, Issue:12

    Topics: Aged; Aminocaproates; Carnosine; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Humans; Mental Disorders; Vigabatrin

1987
Serum carnosinase in blood and homocarnosine in CSF of patients with Følling's disease (PKU).
    Journal of the Oslo city hospitals, 1987, Volume: 37, Issue:4

    Topics: Adolescent; Carnosine; Child; Dipeptidases; Dipeptides; Female; Humans; Infant, Newborn; Male; Middle Aged; Phenylalanine; Phenylketonurias

1987
2-Pyrrolidinone in human cerebrospinal fluid: a major constituent of total gamma-aminobutyric acid.
    Journal of neurochemistry, 1987, Volume: 49, Issue:5

    Topics: Adult; Carnosine; Female; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Humans; Mass Spectrometry; Middle Aged; Pyrrolidinones

1987
Homocarnosinosis: influence of dietary restriction of histidine.
    Neurochemical research, 1986, Volume: 11, Issue:6

    Topics: Adult; Amino Acids; Carnosine; Diet; Dipeptides; Histidine; Humans; Male; Metabolism, Inborn Errors

1986
[Immuno-enhancing actions of carnosine and homocarnosine].
    Nihon seirigaku zasshi. Journal of the Physiological Society of Japan, 1986, Volume: 48, Issue:11

    Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Carnosine; Dipeptides; gamma-Aminobutyric Acid; Immunity; Male; Mice

1986
[Homocarnosine in the brain of rats during cold adaptation].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1985, Volume: 71, Issue:3

    Topics: Adaptation, Physiological; Animals; Atmosphere Exposure Chambers; Brain; Carnosine; Cold Temperature; Dipeptides; Female; Male; Rats; Stress, Physiological; Time Factors

1985
Food intake suppression by histidine.
    Pharmacology, biochemistry, and behavior, 1985, Volume: 23, Issue:5

    Topics: Animals; Brain Chemistry; Carnosine; Circadian Rhythm; Depression, Chemical; Eating; Feeding Behavior; Histidine; Male; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence

1985
[Age and the role of certain mediators in the sensitivity of animals to hyperbaric oxygenation].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1980, Volume: 66, Issue:8

    Topics: Age Factors; Animals; Brain Chemistry; Carnosine; Dipeptides; gamma-Aminobutyric Acid; Histamine; Histidine; Hyperbaric Oxygenation; Neurotransmitter Agents; Rabbits; Rats

1980
Gamma-aminobutyric acid-transaminase deficiency: a newly recognized inborn error of neurotransmitter metabolism.
    Neuropediatrics, 1984, Volume: 15, Issue:3

    Topics: 4-Aminobutyrate Transaminase; beta-Alanine; Brain; Carnosine; Diffuse Cerebral Sclerosis of Schilder; Female; gamma-Aminobutyric Acid; Gigantism; Humans; Infant; Infant, Newborn; Male; Metabolism, Inborn Errors; Neurotransmitter Agents

1984
[Quantitative assay of homocarnosine in cerebrospinal fluid and blood].
    Laboratornoe delo, 1982, Issue:4

    Topics: Carnosine; Central Nervous System Diseases; Child; Child, Preschool; Dipeptides; Humans; Infant; Methods

1982
Endogenous GABA receptor ligands in hypophysial portal blood.
    Neuroendocrinology, 1983, Volume: 37, Issue:3

    Topics: 4-Aminobutyrate Transaminase; Animals; Brain; Carnosine; Electric Stimulation; gamma-Aminobutyric Acid; Male; Pituitary Gland; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A

1983
Cerebrospinal fluid GABA as an index of brain GABA activity.
    Clinical neuropharmacology, 1983, Volume: 6, Issue:3

    Topics: Adult; Aged; Brain; Carnosine; gamma-Aminobutyric Acid; Humans; Middle Aged; Synaptic Transmission

1983
Homocarnosine levels in cerebrospinal fluid of patients with infantile spasms under ACTH therapy.
    Brain & development, 1983, Volume: 5, Issue:5

    Topics: Adrenocorticotropic Hormone; Carnosine; Dipeptides; Humans; Infant; Spasms, Infantile

1983
Cerebrospinal fluid homocarnosine in Huntington's disease.
    Life sciences, 1980, Mar-31, Volume: 26, Issue:13

    Topics: Adult; Aged; Carnosine; Chromatography, Ion Exchange; Dipeptides; Female; Humans; Huntington Disease; Male; Middle Aged; Spectrometry, Fluorescence

1980
Human CSF GABA concentrations: revised downward for controls, but not decreased in Huntington's chorea.
    Journal of neurochemistry, 1982, Volume: 38, Issue:3

    Topics: Carbon Radioisotopes; Carnosine; gamma-Aminobutyric Acid; Humans; Huntington Disease; Reference Values

1982
Transport and distribution of homocarnosine after intracerebroventricular and intravenous injection in the rat.
    Neurochemical research, 1984, Volume: 9, Issue:5

    Topics: Animals; Biological Transport; Brain; Carnosine; Chromatography, High Pressure Liquid; Dipeptides; gamma-Aminobutyric Acid; Injections, Intravenous; Injections, Intraventricular; Male; Rats; Synaptosomes; Tissue Distribution

1984
Homocarnosinosis: lack of serum carnosinase is the defect probably responsible for elevated brain and CSF homocarnosine.
    Clinica chimica acta; international journal of clinical chemistry, 1983, Aug-15, Volume: 132, Issue:2

    Topics: Adult; Brain; Carnosine; Cerebral Cortex; Dipeptidases; Dipeptides; Female; Humans; Kidney; Male; Middle Aged

1983
[Concentration of free amino acids and homocarnosine dipeptide in the cerebrospinal fluid of children with hydrocephalus].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1983, Volume: 83, Issue:10

    Topics: Amino Acids; Carnosine; Cerebral Ventricles; Child, Preschool; Dipeptides; gamma-Aminobutyric Acid; Humans; Hydrocephalus; Infant; Intellectual Disability; Meningitis; Subarachnoid Space

1983
Brain function estimated from the ratio of glutamine to homocarnosine levels in cerebrospinal fluid.
    Brain & development, 1983, Volume: 5, Issue:5

    Topics: Bacterial Infections; Carnosine; Child; Child, Preschool; Dipeptides; Epilepsy; Female; Glutamine; Humans; Infant; Infant, Newborn; Leukemia; Male; Meningeal Neoplasms; Meningitis; Meningitis, Viral; Seizures, Febrile

1983
Increased gamma-aminobutyric acid (GABA), homocarnosine and beta-alanine in cerebrospinal fluid of patients treated with gamma-vinyl GABA (4-amino-hex-5-enoic acid).
    Life sciences, 1981, May-21, Volume: 28, Issue:21

    Topics: 4-Aminobutyrate Transaminase; Adult; Aged; Alanine; Aminocaproates; beta-Alanine; Carnosine; Chromatography, Ion Exchange; Dipeptides; Female; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Spectrometry, Fluorescence; Vigabatrin

1981
Total GABA and homocarnosine in CSF as indices of brain GABA concentrations.
    Neuroscience letters, 1983, Feb-21, Volume: 35, Issue:2

    Topics: Aminocaproates; Animals; Brain; Carnosine; Dipeptides; gamma-Aminobutyric Acid; Male; Rats; Rats, Inbred Strains; Vigabatrin

1983
Biosynthesis of carnosine and related peptides by glial cells in primary culture.
    The Journal of biological chemistry, 1982, Apr-10, Volume: 257, Issue:7

    Topics: Alanine; Animals; Animals, Newborn; Brain; Carnosine; Cells, Cultured; Dipeptides; gamma-Aminobutyric Acid; Kinetics; Mice; Neuroglia

1982
Homocarnosinosis: hypercarnosinuria.
    Journal of neurochemistry, 1982, Volume: 38, Issue:1

    Topics: Adult; Aged; Anserine; Carnosine; Diet; Dipeptidases; Dipeptides; Female; Histidine; Humans; Male; Methylhistidines; Middle Aged; Poultry Products

1982
Does homocarnosine mediate the dyskinetic movements induced by gaba-transaminase inhibitors.
    Neuropharmacology, 1982, Volume: 21, Issue:5

    Topics: 4-Aminobutyrate Transaminase; Animals; Bicuculline; Carnosine; Dipeptides; Dyskinesia, Drug-Induced; Injections, Intraventricular; Picrotoxin; Rats

1982
Human serum carnosinase: characterization, distinction from cellular carnosinase, and activation by cadmium.
    Clinica chimica acta; international journal of clinical chemistry, 1982, Aug-18, Volume: 123, Issue:3

    Topics: Adolescent; Adult; Aged; Aging; Cadmium; Carnosine; Child; Child, Preschool; Dipeptidases; Enzyme Activation; Humans; Infant; Isoelectric Point; Isoenzymes; Kinetics; Middle Aged; Molecular Weight; Substrate Specificity

1982
Artifactual increases in the concentration of free GABA in samples of human cerebrospinal fluid are due to degradation of homocarnosine.
    Journal of neurochemistry, 1982, Volume: 39, Issue:4

    Topics: Carnosine; Dipeptides; False Positive Reactions; gamma-Aminobutyric Acid; Humans; Time Factors

1982
Concentration gradients of free and total gamma-aminobutyric acid and homocarnosine in human CSF: comparison of suboccipital and lumbar sampling.
    Journal of neurochemistry, 1982, Volume: 39, Issue:6

    Topics: Adult; Aged; Carnosine; Dipeptides; Female; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Spinal Puncture

1982
Studies on homocarnosine in cerebrospinal fluid in infancy and childhood. Part I. Homocarnosine level in cerebrospinal fluid of normal infants and children.
    Brain & development, 1981, Volume: 3, Issue:3

    Topics: Aging; Carnosine; Child; Child, Preschool; Dipeptides; Female; Humans; Infant; Infant, Newborn; Male

1981
Studies on homocarnosine in cerebrospinal fluid in infancy and childhood. Part II. Homocarnosine levels in cerebrospinal fluid from children with epilepsy, febrile convulsion or meningitis.
    Brain & development, 1981, Volume: 3, Issue:3

    Topics: Adolescent; Carnosine; Child; Child, Preschool; Consciousness Disorders; Dipeptides; Epilepsy; Female; Humans; Infant; Infant, Newborn; Male; Meningitis; Seizures, Febrile

1981
The effect of gamma-vinyl GABA and gamma-acetylenic GABA on the concentration of homocarnosine in brain and CSF of the rat.
    Brain research, 1980, May-19, Volume: 190, Issue:1

    Topics: Alkynes; Aminocaproates; Animals; Brain; Carnosine; Chromatography, Ion Exchange; Dose-Response Relationship, Drug; Male; Rats; Vigabatrin

1980
[Oxidative stability of Na,K-ATPase].
    Doklady Akademii nauk, 1995, Volume: 342, Issue:4

    Topics: Adenosine Triphosphate; Animals; Carnosine; Cattle; Dogs; Enzyme Stability; Hydrogen Peroxide; Hydrolysis; Hypochlorous Acid; Kinetics; Oxidants; Oxidation-Reduction; Oxygen; Sodium-Potassium-Exchanging ATPase; Temperature

1995
Short applications of gamma-aminobutyric acid increase intracellular calcium concentrations in single identified rat lactotrophs.
    Neuroendocrinology, 1994, Volume: 60, Issue:4

    Topics: Animals; Calcium; Calcium Channel Blockers; Carnosine; Clonazepam; Female; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Immunohistochemistry; Ion Channel Gating; Membrane Potentials; Muscimol; Patch-Clamp Techniques; Pituitary Gland, Anterior; Radioimmunoassay; Rats; Rats, Wistar; Receptors, GABA-A

1994
[The effect of homocarnosine on neuronal activity during satiation and starvation].
    Medicinski pregled, 1993, Volume: 46, Issue:11-12

    Topics: Action Potentials; Animals; Carnosine; Caudate Nucleus; Hippocampus; Neurons; Rabbits; Satiation; Starvation

1993
Amino acid levels in the cerebrospinal fluid of newly diagnosed epileptic patients: effect of vigabatrin and carbamazepine monotherapies.
    Journal of neurochemistry, 1993, Volume: 60, Issue:4

    Topics: Adolescent; Adult; Amino Acids; Aminocaproates; Carbamazepine; Carnosine; Epilepsy; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Humans; Male; Middle Aged; Vigabatrin

1993
Localization of a novel pathway for the liberation of GABA in the human CNS.
    Brain research bulletin, 1994, Volume: 33, Issue:4

    Topics: Animals; Antibody Specificity; Carnosine; Central Nervous System; Dipeptidases; gamma-Aminobutyric Acid; Humans; Immunoenzyme Techniques; Immunohistochemistry; Mice; Mice, Inbred BALB C

1994
Effect of carnosine homocarnosine and anserine on hydroxylation of the guanine moiety in 2'-deoxyguanosine, DNA and nucleohistone with hydrogen peroxide in the presence of nickel(II).
    Carcinogenesis, 1993, Volume: 14, Issue:3

    Topics: Anserine; Carnosine; Deoxyguanosine; DNA; Electron Spin Resonance Spectroscopy; Guanine; Histones; Hydrogen Peroxide; Hydroxylation; Nickel; Oxidation-Reduction

1993
[The effect of hydrogen peroxide and hypochlorite on brain Na,K-ATPase activity].
    Biokhimiia (Moscow, Russia), 1995, Volume: 60, Issue:10

    Topics: Animals; Antioxidants; Brain; Butylated Hydroxytoluene; Carnosine; Cattle; Deferoxamine; Hydrogen Peroxide; Hypochlorous Acid; Sodium-Potassium-Exchanging ATPase; Vitamin E

1995
[Effect of histidine-containing dipeptides on brain tyrosine hydroxylase].
    Biulleten' eksperimental'noi biologii i meditsiny, 1996, Volume: 121, Issue:4

    Topics: Animals; Anserine; Antioxidants; Brain; Carnosine; Histidine; Kinetics; Rats; Substrate Specificity; Tyrosine 3-Monooxygenase

1996
[Comparative investigation of anticonvulsive effects of putrescine and structural analogues of delta-sleep-inducing peptide].
    Vestnik Rossiiskoi akademii meditsinskikh nauk, 1996, Issue:9

    Topics: Animals; Brain; Carnosine; Delta Sleep-Inducing Peptide; gamma-Aminobutyric Acid; Hyperbaric Oxygenation; Lipid Peroxidation; Male; Putrescine; Rats; Seizures

1996
Biochemical and physiological evidence that carnosine is an endogenous neuroprotector against free radicals.
    Cellular and molecular neurobiology, 1997, Volume: 17, Issue:2

    Topics: Animals; Anserine; Brain; Brain Ischemia; Carnosine; Cattle; Free Radicals; Hippocampus; Hydrogen Peroxide; Hypoxia; In Vitro Techniques; Kinetics; Neuroprotective Agents; Pressure; Rats; Respiration; Sodium-Potassium-Exchanging ATPase; Tyrosine 3-Monooxygenase

1997
L-methionine induces stage-dependent changes of differentiation and oxidative activity in sea urchin embryogenesis.
    Pharmacology & toxicology, 1997, Volume: 81, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Anserine; Antioxidants; Carnosine; Chromosome Aberrations; Deoxyguanosine; Embryo, Nonmammalian; Free Radical Scavengers; Germ Cells; Luminescent Measurements; Methionine; Mitosis; Reactive Oxygen Species; Sea Urchins; Stereoisomerism

1997
Homocarnosine and the measurement of neuronal pH in patients with epilepsy.
    Magnetic resonance in medicine, 1997, Volume: 38, Issue:6

    Topics: Adult; Anticonvulsants; Brain Chemistry; Carnosine; Epilepsy; Female; gamma-Aminobutyric Acid; Humans; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurons; Vigabatrin

1997
Toxic effects of beta-amyloid(25-35) on immortalised rat brain endothelial cell: protection by carnosine, homocarnosine and beta-alanine.
    Neuroscience letters, 1998, Feb-13, Volume: 242, Issue:2

    Topics: Amyloid beta-Peptides; Animals; beta-Alanine; Carnosine; Cell Line, Transformed; Endothelium, Vascular; Enzyme Inhibitors; Guanidines; L-Lactate Dehydrogenase; Neuroprotective Agents; Peptide Fragments; Rats; Superoxide Dismutase

1998
Topiramate increases brain GABA, homocarnosine, and pyrrolidinone in patients with epilepsy.
    Neurology, 1999, Volume: 52, Issue:3

    Topics: Adolescent; Adult; Anticonvulsants; Brain; Carnosine; Epilepsy; Female; Fructose; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Pyrrolidinones; Topiramate

1999
Preliminary evidence of low cortical GABA levels in localized 1H-MR spectra of alcohol-dependent and hepatic encephalopathy patients.
    The American journal of psychiatry, 1999, Volume: 156, Issue:6

    Topics: Adult; Age of Onset; Alcoholism; Carnosine; Cerebral Cortex; gamma-Aminobutyric Acid; Hepatic Encephalopathy; Humans; Magnetic Resonance Spectroscopy; Middle Aged; Protons; Radionuclide Imaging

1999
Acute effects of vigabatrin on brain GABA and homocarnosine in patients with complex partial seizures.
    Epilepsia, 1999, Volume: 40, Issue:7

    Topics: Administration, Oral; Adult; Anticonvulsants; Brain; Brain Chemistry; Carnosine; Dose-Response Relationship, Drug; Drug Administration Schedule; Epilepsy, Complex Partial; Female; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Occipital Lobe; Vigabatrin

1999
Hydrogen peroxide-mediated Cu,Zn-superoxide dismutase fragmentation: protection by carnosine, homocarnosine and anserine.
    Biochimica et biophysica acta, 1999, Nov-16, Volume: 1472, Issue:3

    Topics: Anserine; Carnosine; Electrophoresis, Polyacrylamide Gel; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Pentetic Acid; Superoxide Dismutase

1999
Carnosine protects against excitotoxic cell death independently of effects on reactive oxygen species.
    Neuroscience, 1999, Volume: 94, Issue:2

    Topics: Animals; Apoptosis; Carnosine; Cells, Cultured; Kainic Acid; Kinetics; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Rats; Rats, Wistar; Reactive Oxygen Species

1999
Effects of gabapentin on brain GABA, homocarnosine, and pyrrolidinone in epilepsy patients.
    Epilepsia, 2000, Volume: 41, Issue:6

    Topics: Acetates; Adult; Amines; Anticonvulsants; Brain Chemistry; Carnosine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Occipital Lobe; Pyrrolidinones

2000
Aminoacyl-histidine dipeptides in the glial cells of the adult rabbit forebrain.
    Peptides, 2000, Volume: 21, Issue:11

    Topics: Animals; Brain; Carnosine; Cell Division; Cell Movement; Glial Fibrillary Acidic Protein; Histidine; Immunohistochemistry; Neural Cell Adhesion Molecules; Neuroglia; Peptides; Rabbits; Rats; Rats, Wistar

2000
Homocarnosine elevations: a cause or a sign of seizure control?
    Neurology, 2001, Mar-27, Volume: 56, Issue:6

    Topics: Carnosine; Epilepsy; Humans; Magnetic Resonance Spectroscopy

2001
Homocarnosine and seizure control in juvenile myoclonic epilepsy and complex partial seizures.
    Neurology, 2001, Mar-27, Volume: 56, Issue:6

    Topics: Adult; Aged; Carnosine; Epilepsy, Complex Partial; Female; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Myoclonic Epilepsy, Juvenile; Time Factors

2001
Reductions in occipital cortex GABA levels in panic disorder detected with 1h-magnetic resonance spectroscopy.
    Archives of general psychiatry, 2001, Volume: 58, Issue:6

    Topics: Adult; Agoraphobia; Ambulatory Care; Carnosine; Female; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Spectroscopy; Male; Occipital Lobe; Panic Disorder

2001
Topiramate rapidly raises brain GABA in epilepsy patients.
    Epilepsia, 2001, Volume: 42, Issue:4

    Topics: Administration, Oral; Anticonvulsants; Brain Chemistry; Carnosine; Dose-Response Relationship, Drug; Drug Administration Schedule; Epilepsy, Complex Partial; Fructose; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Occipital Lobe; Pyrrolidinones; Stimulation, Chemical; Topiramate

2001
Peculiarities of carnosine metabolism in a patient with pronounced homocarnosinemia.
    Bulletin of experimental biology and medicine, 2001, Volume: 132, Issue:4

    Topics: Adolescent; Anserine; Carnosine; Chromatography, High Pressure Liquid; Dipeptidases; Dose-Response Relationship, Drug; Female; Humans; Male; Syndrome

2001
Differential expression of carnosine, homocarnosine and N-acetyl-L-histidine hydrolytic activities in cultured rat macroglial cells.
    Journal of molecular neuroscience : MN, 2001, Volume: 17, Issue:3

    Topics: Amidohydrolases; Animals; Brain; Carnosine; Cells, Cultured; Chromatography, High Pressure Liquid; Histidine; Hydrolysis; Neuroglia; Neurons; Oligodendroglia; Rats

2001
Effect of carnosine and related compounds on the inactivation of human Cu,Zn-superoxide dismutase by modification of fructose and glycolaldehyde.
    Bioscience, biotechnology, and biochemistry, 2002, Volume: 66, Issue:1

    Topics: Acetaldehyde; Anserine; Carnosine; Dipeptides; Enzyme Activation; Free Radical Scavengers; Fructose; Histidine; Humans; Hydroxyl Radical; Superoxide Dismutase

2002
Protection by carnosine-related dipeptides against hydrogen peroxide-mediated ceruloplasmin modification.
    Molecules and cells, 2002, Feb-28, Volume: 13, Issue:1

    Topics: Animals; Anserine; Antioxidants; Carnosine; Ceruloplasmin; Copper; Humans; Hydrogen Peroxide; Hydroxyl Radical; In Vitro Techniques; Oxidation-Reduction; Peptide Fragments

2002
Protective effects of carnosine, homocarnosine and anserine against peroxyl radical-mediated Cu,Zn-superoxide dismutase modification.
    Biochimica et biophysica acta, 2002, Mar-15, Volume: 1570, Issue:2

    Topics: Amidines; Anserine; Carnosine; Catalase; Chelating Agents; Free Radical Scavengers; Free Radicals; Hydrogen-Ion Concentration; Oxidants; Oxidation-Reduction; Peroxides; Superoxide Dismutase; Time Factors

2002
Neuroprotective effects of carnosine and homocarnosine on pheochromocytoma PC12 cells exposed to ischemia.
    Journal of neuroscience research, 2002, May-15, Volume: 68, Issue:4

    Topics: Animals; Carnosine; Cell Death; Dinoprostone; Ischemia; Neuroprotective Agents; PC12 Cells; Radioimmunoassay; Rats

2002
Carnosine and related dipeptides protect human ceruloplasmin against peroxyl radical-mediated modification.
    Molecules and cells, 2002, Jun-30, Volume: 13, Issue:3

    Topics: Anserine; Antioxidants; Carnosine; Ceruloplasmin; Dipeptides; Drug Antagonism; Humans; Peroxides

2002
A proton magnetic resonance spectroscopy study of metabolites in the occipital lobes in epilepsy.
    Epilepsia, 2003, Volume: 44, Issue:4

    Topics: Adolescent; Adult; Aspartic Acid; Carnosine; Epilepsies, Partial; Epilepsy, Generalized; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Image Enhancement; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neural Inhibition; Occipital Lobe; Synaptic Transmission

2003
Synthesis of homocarnosine in muscle in vivo.
    Biochimica et biophysica acta, 1961, Jul-08, Volume: 50

    Topics: Biochemical Phenomena; Carnosine; Muscles; Peptides

1961
Isolation of gamma-aminobutyrylhistidine (homocarnosine) from brain.
    The Journal of biological chemistry, 1961, Volume: 236

    Topics: Brain; Brain Chemistry; Carnosine; Humans; Peptides

1961
The distribution of homocarnosine in mammals.
    Archives of biochemistry and biophysics, 1962, Volume: 99

    Topics: Animals; Brain; Carnosine; Humans; Mammals; Peptides

1962
UPTAKE OF CARNOSINE AND HOMOCARNOSINE BY RAT BRAIN SLICES.
    Archives of biochemistry and biophysics, 1964, Volume: 104

    Topics: Amino Acids; Brain; Carbon Isotopes; Carnosine; Dipeptides; Histidine; Metabolism; Peptides; Rats; Research; Sarcoma; Sarcoma, Experimental; Tissue Culture Techniques

1964
OCCURRENCE OF HOMOCARNOSINE (GAMMA-AMINOBUTYRYLHISTIDINE) IN THE BRAIN OF RANA ESCULENTA.
    Journal of neurochemistry, 1964, Volume: 11

    Topics: Animals; Anura; Brain; Brain Chemistry; Carnosine; Imidazoles; Rana esculenta; Research

1964
Acrolein-sequestering ability of endogenous dipeptides: characterization of carnosine and homocarnosine/acrolein adducts by electrospray ionization tandem mass spectrometry.
    Journal of mass spectrometry : JMS, 2003, Volume: 38, Issue:9

    Topics: Acrolein; Alzheimer Disease; Carnosine; Cytotoxins; Molecular Structure; Spectrometry, Mass, Electrospray Ionization

2003
Determination of liposomal encapsulation efficiency using proton NMR spectroscopy.
    Chemistry and physics of lipids, 2004, Volume: 127, Issue:1

    Topics: Carnosine; Deuterium; Hydrogen-Ion Concentration; Liposomes; Magnetic Resonance Spectroscopy; Organometallic Compounds; Organophosphorus Compounds; Phospholipids; Protons

2004
Apoptotic characteristics of cell death and the neuroprotective effect of homocarnosine on pheochromocytoma PC12 cells exposed to ischemia.
    Journal of neuroscience research, 2004, Feb-15, Volume: 75, Issue:4

    Topics: Animals; Apoptosis; Carnosine; Cell Death; Cell Hypoxia; Neuroprotective Agents; PC12 Cells; Phosphorylation; Rats

2004
Separation and determination of carnosine-related peptides using capillary electrophoresis with laser-induced fluorescence detection.
    Electrophoresis, 2005, Volume: 26, Issue:3

    Topics: Adolescent; Adult; Animals; Anserine; Benzoates; Carnosine; Cerebrospinal Fluid; Electrophoresis, Capillary; Humans; Lasers; Meat; Middle Aged; Muscles; Peptides; Quinolines; Sheep; Spectrometry, Fluorescence; Sus scrofa

2005
A novel, quantitative assay for homocarnosine in cerebrospinal fluid using stable-isotope dilution liquid chromatography-tandem mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2006, Jan-18, Volume: 830, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Carnosine; Child; Child, Preschool; Chromatography, High Pressure Liquid; Deuterium; Female; gamma-Aminobutyric Acid; Humans; Infant; Male; Mass Spectrometry; Middle Aged; Radioisotope Dilution Technique; Reference Standards; Reference Values; Reproducibility of Results

2006
Carnosine and related dipeptides as quenchers of reactive carbonyl species: from structural studies to therapeutic perspectives.
    BioFactors (Oxford, England), 2005, Volume: 24, Issue:1-4

    Topics: Acrolein; Aldehydes; Animals; Anserine; Carnosine; Chromatography, Liquid; Dipeptides; Histidine; Muscle, Skeletal; Oxidation-Reduction; Rats; Spectrometry, Mass, Electrospray Ionization

2005
Brain homocarnosine and seizure control of patients taking gabapentin or topiramate.
    Epilepsia, 2006, Volume: 47, Issue:3

    Topics: Adult; Amines; Anticonvulsants; Brain Chemistry; Carnosine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsy, Complex Partial; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neocortex; Topiramate; Treatment Outcome; Visual Cortex

2006
Homology modeling of human serum carnosinase, a potential medicinal target, and MD simulations of its allosteric activation by citrate.
    Journal of medicinal chemistry, 2006, Jun-01, Volume: 49, Issue:11

    Topics: Allosteric Regulation; Amidohydrolases; Anions; Anserine; Carnosine; Catalytic Domain; Citric Acid; Computer Simulation; Dipeptidases; Enzyme Activation; Humans; Models, Molecular; Protein Binding; Protein Conformation; Sequence Homology, Amino Acid; Serum

2006
Field-amplified on-line sample stacking for determination of carnosine-related peptides by capillary electrophoresis.
    Journal of separation science, 2006, Volume: 29, Issue:7

    Topics: Anserine; Carnosine; Electrophoresis, Capillary; Reproducibility of Results; Sensitivity and Specificity; Solvents

2006
Protective effects of histidine dipeptides on the modification of neurofilament-L by the cytochrome c/hydrogen peroxide system.
    Journal of biochemistry and molecular biology, 2007, Jan-31, Volume: 40, Issue:1

    Topics: Animals; Anserine; Antioxidants; Carnosine; Cytochromes c; Dipeptides; Histidine; Hydrogen Peroxide; Mice; Neurofilament Proteins; Oxidation-Reduction; Protective Agents; Tyrosine

2007
Ferritin enhances salsolinol-mediated DNA strand breakage: protection by carnosine and related compounds.
    Toxicology letters, 2009, Jul-10, Volume: 188, Issue:1

    Topics: Anserine; Carnosine; Catalase; DNA Breaks, Single-Stranded; DNA, Superhelical; Escherichia coli; Ferritins; Ferrozine; Free Radical Scavengers; Hydroxides; Iron Chelating Agents; Isoquinolines; Lac Operon; Mutation; Oxidative Stress; Superoxide Dismutase; Time Factors

2009
Hepatocyte transplantation (HTx) corrects selected neurometabolic abnormalities in murine intermediate maple syrup urine disease (iMSUD).
    Biochimica et biophysica acta, 2009, Volume: 1792, Issue:10

    Topics: Animals; Brain; Carnosine; gamma-Aminobutyric Acid; Hepatocytes; Humans; Liver; Maple Syrup Urine Disease; Mice; Models, Biological; Neurotransmitter Agents

2009
Relevance of allosteric conformations and homocarnosine concentration on carnosinase activity.
    Amino acids, 2010, Volume: 38, Issue:5

    Topics: Adult; Allosteric Regulation; Animals; Blotting, Western; Carnosine; Child; Dipeptidases; Female; Humans; Male; Mice; Mice, Inbred BALB C; Middle Aged; Reference Values

2010
Reaction of ferritin with hydrogen peroxide induces lipid peroxidation.
    BMB reports, 2010, Volume: 43, Issue:3

    Topics: Anserine; Azides; Carnosine; Deferoxamine; Ferritins; Free Radical Scavengers; Hydrogen Peroxide; Iron Chelating Agents; Lipid Peroxidation; Thiourea

2010
Protective effects of carnosine and homocarnosine on ferritin and hydrogen peroxide-mediated DNA damage.
    BMB reports, 2010, Volume: 43, Issue:10

    Topics: Antioxidants; Carnosine; DNA Damage; Ferritins; Hydrogen Peroxide; Hydroxyl Radical; In Vitro Techniques; Lac Operon; Mutagenesis; Mutagenicity Tests; Oxidation-Reduction; Plasmids

2010
Measurement of carnosine, homocarnosine and anserine by FASI capillary electrophoresis UV detection: applications on biological samples.
    Talanta, 2011, May-15, Volume: 84, Issue:3

    Topics: Anserine; Carnosine; Electrophoresis, Capillary; Spectrophotometry, Ultraviolet

2011
Carnosine treatment largely prevents alterations of renal carnosine metabolism in diabetic mice.
    Amino acids, 2012, Volume: 42, Issue:6

    Topics: Age Factors; Animals; Animals, Genetically Modified; Anserine; Capillary Permeability; Carnosine; Diabetes Mellitus; Diabetic Nephropathies; Dipeptidases; Disease Models, Animal; Humans; Kidney; Mice; Proteinuria

2012
Behavioral metabolomics analysis identifies novel neurochemical signatures in methamphetamine sensitization.
    Genes, brain, and behavior, 2013, Volume: 12, Issue:8

    Topics: Animals; Brain; Butyrates; Carnosine; Central Nervous System Sensitization; Guanidines; Inositol; Male; Metabolome; Methamphetamine; Mice; Mice, Inbred C57BL; Pantothenic Acid

2013
Copper(II)-chelating homocarnosine glycoconjugate as a new multifunctional compound.
    Journal of inorganic biochemistry, 2014, Volume: 131

    Topics: Amyloid beta-Peptides; Carnosine; Chelating Agents; Circular Dichroism; Coordination Complexes; Copper; Drug Stability; Electron Spin Resonance Spectroscopy; Glycoconjugates; Magnetic Resonance Spectroscopy; Spectrophotometry, Ultraviolet; Superoxide Dismutase; Trehalose

2014
Metabolite proofreading in carnosine and homocarnosine synthesis: molecular identification of PM20D2 as β-alanyl-lysine dipeptidase.
    The Journal of biological chemistry, 2014, Jul-11, Volume: 289, Issue:28

    Topics: Animals; Carnosine; Dipeptidases; Dipeptides; HEK293 Cells; Humans; Mass Spectrometry; Mice; Organ Specificity; Peptide Synthases; Rats; Recombinant Proteins; Substrate Specificity

2014
Exploratory Metabolomic Analyses Reveal Compounds Correlated with Lutein Concentration in Frontal Cortex, Hippocampus, and Occipital Cortex of Human Infant Brain.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: Carnosine; Dietary Supplements; Energy Metabolism; Female; Frontal Lobe; Hippocampus; Humans; Infant; Infant, Newborn; Lipid Metabolism; Lutein; Male; Metabolomics; Occipital Lobe

2015
Carnosine and Homocarnosine Degradation Mechanisms by the Human Carnosinase Enzyme CN1: Insights from Multiscale Simulations.
    Biochemistry, 2016, 05-17, Volume: 55, Issue:19

    Topics: Carnosine; Catalytic Domain; Dipeptidases; Humans; Hydrogen Bonding; Molecular Dynamics Simulation; Zinc

2016
Computational approaches in the rational design of improved carbonyl quenchers: focus on histidine containing dipeptides.
    Future medicinal chemistry, 2016, Volume: 8, Issue:14

    Topics: Animals; Anserine; Carnosine; Computer Simulation; Dipeptides; Drug Design; Histidine; Humans; Stereoisomerism

2016
l-Homocarnosine attenuates inflammation in cerebral ischemia-reperfusion injury through inhibition of nod-like receptor protein 3 inflammasome.
    International journal of biological macromolecules, 2018, Oct-15, Volume: 118, Issue:Pt A

    Topics: Animals; Apoptosis; Carnosine; Catalase; Dietary Supplements; Gene Expression Regulation; Humans; Infarction, Middle Cerebral Artery; Inflammasomes; Inflammation; Interleukin-6; Lipid Peroxidation; Microscopy, Fluorescence; NLR Family, Pyrin Domain-Containing 3 Protein; Rats; Reperfusion Injury; Tumor Necrosis Factor-alpha

2018
Synergistic effect of vancomycin and l-homocarnosine alleviates Staphylococcus aureus-induced osteomyelitis in rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 111

    Topics: Animals; Anti-Bacterial Agents; Carnosine; Drug Synergism; Drug Therapy, Combination; Male; Osteomyelitis; Rats; Staphylococcal Infections; Staphylococcus aureus; Vancomycin

2019
[Determination of anserine, homocarnosine and carnosine in meat products by ion chromatography with integrated pulsed amperometric detection].
    Se pu = Chinese journal of chromatography, 2018, Dec-08, Volume: 36, Issue:12

    Topics: Animals; Anserine; Carnosine; Chromatography, Ion Exchange; Ducks; Food Contamination; Geese; Meat Products

2018
Diurnal variability of cerebral metabolites in healthy human brain with 2D localized correlation spectroscopy (2D L-COSY).
    Journal of magnetic resonance imaging : JMRI, 2019, Volume: 50, Issue:2

    Topics: Adult; Aspartic Acid; Brain; Carnosine; Choline; Circadian Rhythm; Creatine; Cross-Over Studies; Female; Fucose; Glutathione; Healthy Volunteers; Humans; Inositol; Lipid Metabolism; Magnetic Resonance Spectroscopy; Male; Middle Aged; Reference Values; Reproducibility of Results; Young Adult

2019
MEGA-PRESS of GABA+: Influences of acquisition parameters.
    NMR in biomedicine, 2021, Volume: 34, Issue:5

    Topics: Carnosine; Computer Simulation; gamma-Aminobutyric Acid; Humans; Macromolecular Substances; Magnetic Resonance Spectroscopy

2021
Activation Effects of Carnosine- and Histidine-Containing Dipeptides on Human Carbonic Anhydrases: A Comprehensive Study.
    International journal of molecular sciences, 2020, Mar-04, Volume: 21, Issue:5

    Topics: Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase IX; Carbonic Anhydrase V; Carbonic Anhydrases; Carnosine; Chelating Agents; Dipeptides; Histidine; Humans; Kinetics; Models, Molecular; Protein Domains; Protons; Software

2020
Elevated homocarnosine and GABA in subject on isoniazid as assessed through 1H MRS at 7T.
    Analytical biochemistry, 2020, 06-15, Volume: 599

    Topics: Adult; Brain Chemistry; Carnosine; Female; gamma-Aminobutyric Acid; Healthy Volunteers; Humans; Isoniazid; Magnetic Resonance Spectroscopy; Male; Middle Aged; Young Adult

2020
Dietary GABA induces endogenous synthesis of a novel imidazole peptide homocarnosine in mouse skeletal muscles.
    Amino acids, 2020, Volume: 52, Issue:5

    Topics: Animals; beta-Alanine; Carnosine; Diet; Feeding Behavior; GABA Agents; gamma-Aminobutyric Acid; Imidazoles; Male; Mice; Mice, Inbred ICR; Muscle, Skeletal

2020
Biochemical Correlations with Fatigue in Multiple Sclerosis Detected by MR 2D Localized Correlated Spectroscopy.
    Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2021, Volume: 31, Issue:3

    Topics: Adult; Aspartic Acid; Carnosine; Choline; Creatine; Fatigue; Female; Glutathione; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Young Adult

2021