Page last updated: 2024-08-21

carnosine and 4-hydroxy-2-nonenal

carnosine has been researched along with 4-hydroxy-2-nonenal in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (33.33)29.6817
2010's12 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aldini, G; Beretta, G; Bradamante, S; Carini, M; Facino, RM1
Liu, Y; Sayre, LM; Xu, G1
Borin, G; Calderan, A; Guiotto, A; Jo, DG; Mattson, MP; Osler, A; Rubini, C; Ruzza, P1
Aldini, G; Beretta, G; Carini, M; Facino, RM1
Aldini, G; Beretta, G; Carini, M; Facino, RM; Granata, P; Marinello, C1
Gavin, T; Geohagen, BC; Lopachin, RM1
Benderdour, M; Buschmann, MD; Côté, JF; El-Bikai, R; Fahmi, H; Fernandes, JC; Macqueen, L; Maghni, K; Margaron, Y; Shi, Q; Welman, M1
Bertinaria, M; Buonsanti, MF; Carabelli, V; Daniele, PG; Fruttero, R; Gasco, A; Gavello, D; Giorgis, M; Guglielmo, S; Montanaro, G; Rolando, B1
Babizhayev, MA; Kasus-Jacobi, A; Li, F; Marchette, LD; Wang, H1
Benetti, E; Bertinaria, M; Collino, M; Daniele, PG; Fruttero, R; Gasco, A; Giorgis, M; Marini, E; Montanaro, G; Rolando, B1
Aldini, G; Carini, M; De Maddis, D; Pallavicini, M; Pedretti, A; Straniero, V; Testa, B; Valoti, E; Vistoli, G1
Aldini, G; Carini, M; Vistoli, G; Yeum, KJ1
Abusarah, J; Benderdour, M; Fahmi, H; Fernandes, JC; Moldovan, F; Shi, Q; Zaouter, C1
Bogdanowicz, P; Camaré, C; Garoby-Salom, S; Grazide, MH; Josse, G; Larroque-Cardoso, P; Nadal-Wollbold, F; Nègre-Salvayre, A; Pucelle, M; Salvayre, R; Schmitt, AM; Uchida, K; Zarkovic, K1
Bauerova, K; Danisovic, L; Drafi, F; Fedorova, T; Kuncirova, V; Mihalova, D; Ondrejickova, O; Ponist, S; Rackova, L; Trunova, O; Tumova, I1
Aldini, G; Carini, M; Casali, G; Colzani, M; De Maddis, D; Vistoli, G1
Anderson, EJ; Builta, ZJ; Doorn, JA; Monroe, TB; Nelson, MM1
Ali, TFS; Biswas, T; Fujita, M; Koga, R; Miyoshi, J; Morioka, M; Negoto, T; Noguchi, K; Okamoto, Y; Orito, K; Otsuka, M; Taira, N1

Reviews

1 review(s) available for carnosine and 4-hydroxy-2-nonenal

ArticleYear
Novel molecular approaches for improving enzymatic and nonenzymatic detoxification of 4-hydroxynonenal: toward the discovery of a novel class of bioactive compounds.
    Free radical biology & medicine, 2014, Volume: 69

    Topics: Advanced Oxidation Protein Products; Aldehydes; Carnosine; Fatty Acids, Omega-6; Free Radicals; Humans; Lipid Peroxidation; Metabolic Detoxication, Phase I

2014

Other Studies

17 other study(ies) available for carnosine and 4-hydroxy-2-nonenal

ArticleYear
Carnosine is a quencher of 4-hydroxy-nonenal: through what mechanism of reaction?
    Biochemical and biophysical research communications, 2002, Nov-15, Volume: 298, Issue:5

    Topics: Aldehydes; Animals; Carnosine; In Vitro Techniques; Lipid Peroxidation; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Models, Biological; Muscle, Skeletal; Oxidation-Reduction; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances

2002
Carnosine inhibits (E)-4-hydroxy-2-nonenal-induced protein cross-linking: structural characterization of carnosine-HNE adducts.
    Chemical research in toxicology, 2003, Volume: 16, Issue:12

    Topics: Aldehydes; Animals; Carnosine; Cattle; Chelating Agents; Copper Sulfate; Cross-Linking Reagents; Guanidines; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Pancreas; Pentetic Acid; Ribonuclease, Pancreatic

2003
Synthesis and evaluation of neuroprotective alpha,beta-unsaturated aldehyde scavenger histidyl-containing analogues of carnosine.
    Journal of medicinal chemistry, 2005, Sep-22, Volume: 48, Issue:19

    Topics: Aldehydes; Animals; Carnosine; Cell Death; Cell Line, Tumor; Cells, Cultured; Cytoprotection; Hippocampus; Histidine; Humans; Neurons; Neuroprotective Agents; Rats; Structure-Activity Relationship

2005
Carnosine and related dipeptides as quenchers of reactive carbonyl species: from structural studies to therapeutic perspectives.
    BioFactors (Oxford, England), 2005, Volume: 24, Issue:1-4

    Topics: Acrolein; Aldehydes; Animals; Anserine; Carnosine; Chromatography, Liquid; Dipeptides; Histidine; Muscle, Skeletal; Oxidation-Reduction; Rats; Spectrometry, Mass, Electrospray Ionization

2005
Effects of UVB radiation on 4-hydroxy-2-trans-nonenal metabolism and toxicity in human keratinocytes.
    Chemical research in toxicology, 2007, Volume: 20, Issue:3

    Topics: Aldehydes; Carnosine; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liquid; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Radiation; Glutathione; Humans; Keratinocytes; Oxidative Stress; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Ultraviolet Rays

2007
Synaptosomal toxicity and nucleophilic targets of 4-hydroxy-2-nonenal.
    Toxicological sciences : an official journal of the Society of Toxicology, 2009, Volume: 107, Issue:1

    Topics: Acetylcysteine; Acrolein; Aldehydes; Amino Acids; Animals; Biological Transport; Carnosine; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Male; Mechanics; Nonlinear Dynamics; Oxidative Stress; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Regression Analysis; Sulfhydryl Compounds; Synaptosomes; Transport Vesicles; Tritium

2009
Perturbation of adhesion molecule-mediated chondrocyte-matrix interactions by 4-hydroxynonenal binding: implication in osteoarthritis pathogenesis.
    Arthritis research & therapy, 2010, Volume: 12, Issue:5

    Topics: Aged; Aldehydes; Blotting, Western; Carnosine; Cell Adhesion Molecules; Cell Separation; Cells, Cultured; Chondrocytes; Collagen Type II; Extracellular Matrix; Flow Cytometry; Fluorescent Antibody Technique; Gene Expression Profiling; Humans; Immunoprecipitation; Microscopy, Confocal; Osteoarthritis; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction

2010
Synthesis, physicochemical characterization, and biological activities of new carnosine derivatives stable in human serum as potential neuroprotective agents.
    Journal of medicinal chemistry, 2011, Jan-27, Volume: 54, Issue:2

    Topics: Aldehydes; Animals; Antioxidants; Blood-Brain Barrier; Carnosine; Cations, Divalent; Cell Death; Chelating Agents; Copper; Dipeptides; Drug Stability; Free Radical Scavengers; Hippocampus; Humans; In Vitro Techniques; Lipoproteins, LDL; Male; Mice; Neurons; Neuroprotective Agents; Oxidation-Reduction; Protein Carbonylation; Rats; Rats, Wistar; Serum; Structure-Activity Relationship

2011
Carcinine has 4-hydroxynonenal scavenging property and neuroprotective effect in mouse retina.
    Investigative ophthalmology & visual science, 2012, Jun-20, Volume: 53, Issue:7

    Topics: Aldehydes; Animals; BALB 3T3 Cells; Carnosine; Chromatography, High Pressure Liquid; Electroretinography; Eye Proteins; Mass Spectrometry; Mice; Neuroprotective Agents; Oxidative Stress; Retina; Retinal Degeneration; Retinal Dehydrogenase

2012
Carnosine analogues containing NO-donor substructures: synthesis, physico-chemical characterization and preliminary pharmacological profile.
    European journal of medicinal chemistry, 2012, Volume: 54

    Topics: Aldehydes; Animals; Antioxidants; Carnosine; Chemical Phenomena; Chemistry Techniques, Synthetic; Copper; Drug Stability; Humans; Hydrophobic and Hydrophilic Interactions; In Vitro Techniques; Male; Nitric Oxide; Rats; Reperfusion Injury; Vasodilation

2012
Exploring the space of histidine containing dipeptides in search of novel efficient RCS sequestering agents.
    European journal of medicinal chemistry, 2013, Volume: 66

    Topics: Adult; Aldehydes; Carnosine; Dipeptides; Histidine; Humans; Models, Molecular; Protein Stability; Proteolysis; Pyridoxal

2013
New evidence implicating 4-hydroxynonenal in the pathogenesis of osteoarthritis in vivo.
    Arthritis & rheumatology (Hoboken, N.J.), 2014, Volume: 66, Issue:9

    Topics: Aldehydes; Animals; Arthritis, Experimental; Carnosine; Cartilage, Articular; Dogs; Knee Joint; Osteoarthritis, Knee

2014
Elastin Modification by 4-Hydroxynonenal in Hairless Mice Exposed to UV-A. Role in Photoaging and Actinic Elastosis.
    The Journal of investigative dermatology, 2015, Volume: 135, Issue:7

    Topics: Aldehydes; Animals; Carnosine; Disease Models, Animal; Elasticity; Elastin; Lipid Peroxidation; Mice; Mice, Hairless; Oxidative Stress; Photosensitivity Disorders; Random Allocation; Sensitivity and Specificity; Skin Aging; Ultraviolet Rays

2015
Effect of Carnosine in Experimental Arthritis and on Primary Culture Chondrocytes.
    Oxidative medicine and cellular longevity, 2016, Volume: 2016

    Topics: Adjuvants, Immunologic; Aldehydes; Animals; Arthritis, Experimental; Body Weight; Carnosine; Carrageenan; Cell Survival; Cells, Cultured; Chondrocytes; Edema; Hydrogen Peroxide; Interleukin-1alpha; Intracellular Space; Luminescent Measurements; Male; Malondialdehyde; Oxidative Stress; Protein Carbonylation; Rats, Inbred Lew; Rats, Wistar

2016
Reactivity, Selectivity, and Reaction Mechanisms of Aminoguanidine, Hydralazine, Pyridoxamine, and Carnosine as Sequestering Agents of Reactive Carbonyl Species: A Comparative Study.
    ChemMedChem, 2016, Aug-19, Volume: 11, Issue:16

    Topics: Aldehydes; Carnosine; Dose-Response Relationship, Drug; Glyoxal; Guanidines; Humans; Hydralazine; Malondialdehyde; Molecular Structure; Pyridoxamine; Pyruvaldehyde; Sequestering Agents; Structure-Activity Relationship

2016
Biochemical characterization of the catecholaldehyde reactivity of L-carnosine and its therapeutic potential in human myocardium.
    Amino acids, 2019, Volume: 51, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Aldehydes; Carnosine; Catechols; Cysteine; Glutathione; Humans; Middle Aged; Mitochondria; Myocardium; Oxidation-Reduction

2019
Neuroprotective effects of a novel carnosine-hydrazide derivative on hippocampal CA1 damage after transient cerebral ischemia.
    European journal of medicinal chemistry, 2019, Feb-01, Volume: 163

    Topics: Aldehydes; Animals; CA1 Region, Hippocampal; Carnosine; Cell Death; Gerbillinae; HSP70 Heat-Shock Proteins; Hydrazines; Ischemic Attack, Transient; Neurons; Neuroprotective Agents; PC12 Cells; Rats; Reperfusion Injury

2019