carnitine has been researched along with trimethyloxamine in 112 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (2.68) | 18.7374 |
| 1990's | 4 (3.57) | 18.2507 |
| 2000's | 3 (2.68) | 29.6817 |
| 2010's | 57 (50.89) | 24.3611 |
| 2020's | 45 (40.18) | 2.80 |
| Authors | Studies |
|---|---|
| Bradley, TM; Tremblay, GC | 1 |
| Rebouche, CJ | 1 |
| Chenard, CA; Rebouche, CJ | 1 |
| Banjac, B; Drewes, LR; Kloiber, O | 1 |
| Charest, R; Dunn, A | 1 |
| Evans, AM; Longo, A; Mancinelli, A; Shanahan, K | 1 |
| BEMM, H; ROTZSCH, W; STRACK, E | 1 |
| Bain, MA; Evans, AM; Milne, RW | 1 |
| Beckwith-Hall, B; Bingham, S; Cloarec, O; Cross, AJ; Holmes, E; Lindon, JC; Nicholson, JK; Powell, J; Stella, C; van der Ouderaa, F | 1 |
| Bain, MA; Evans, AM; Faull, R; Milne, RW | 1 |
| Britt, EB; Brown, JM; Buffa, JA; Bushman, FD; Chen, J; DiDonato, JA; Fu, X; Hazen, SL; Koeth, RA; Krauss, RM; Levison, BS; Lewis, JD; Li, H; Li, L; Lusis, AJ; Org, E; Sheehy, BT; Smith, JD; Tang, WH; Wang, Z; Warrier, M; Wu, GD; Wu, Y | 1 |
| Dambrova, M; Grinberga, S; Kalvins, I; Konrade, I; Liepins, E; Petrovska, R; Pugovics, O; Skapare-Makarova, E; Tirzite, D | 1 |
| Miller, MJ | 1 |
| Arduini, A; Lopaschuk, GD; Ussher, JR | 1 |
| Brown, JM; Hazen, SL | 1 |
| Barros, AS; Bom, AT; Bousquet, J; Carrola, J; Duarte, IF; Gil, AM; Gomes, J; Loureiro, CC; Rocha, SM | 1 |
| Allayee, H; Bennett, BJ; Hartiala, J; Hazen, SL; Lusis, AJ; McPherson, R; Roberts, R; Stewart, AF; Tang, WH; Wang, Z | 1 |
| Hazen, SL; Tang, WH | 1 |
| Cirule, H; Dambrova, M; Grinberga, S; Gustina, D; Kuka, J; Liepins, J; Liepinsh, E; Loza, E; Makrecka-Kuka, M; Pugovics, O; Zharkova-Malkova, O | 1 |
| Buffa, JA; Culley, MK; DiDonato, JA; Gregory, JC; Hazen, SL; Koeth, RA; Levison, BS; Li, L; Lusis, AJ; Org, E; Smith, JD; Tang, WHW; Wang, Z; Wu, Y | 1 |
| Fukami, K; Kaida, Y; Okuda, S; Sakai, K; Shimizu, M; Takeuchi, M; Ueda, S; Wada, Y; Yamagishi, S; Yamazaki, H; Yokoro, M | 1 |
| Drosos, I; Kolios, G; Tavridou, A | 1 |
| Dambrova, M; Grinberga, S; Hartmane, D; Konrade, I; Latkovskis, G; Liepinsh, E; Pugovics, O; Sevostjanovs, E; Strele, I | 1 |
| Amaral, AC; Fouque, D; Mafra, D; Moraes, C | 1 |
| Boutagy, NE; Davy, BM; Davy, KP; Englund, TR; Hulver, MW; Neilson, AP; Osterberg, KL; Smithson, AT | 2 |
| Berge, RK; Bjørndal, B; Bruheim, I; Lindquist, C; Nordrehaug, JE; Nygård, O; Ramsvik, MS; Svardal, A | 1 |
| Adelman, SJ; Bellamine, A; Collins, HL; Drazul-Schrader, D; Koster, PD; Owen, K; Sanli, T; Sulpizio, AC; Williamson, Y | 1 |
| Berge, RK; Bjørndal, B; Bohov, P; Bruheim, I; Nordrehaug, JE; Ramsvik, MS; Rostrup, E; Svardal, A | 1 |
| Abbas, A; Aukrust, P; Berge, RK; Bjerkeli, V; Gregersen, I; Halvorsen, B; Holm, S; Hov, JE; Karlsen, TH; Kummen, M; Reier-Nilsen, F; Russell, D; Skagen, K; Skjelland, M; Svardal, A; Trøseid, M; Ueland, T | 1 |
| Aadland, EK; Bertram, HC; Clausen, MR; Eng, Ø; Graff, IE; Holthe, A; Jacques, H; Lavigne, C; Liaset, B; Mellgren, G; Schmedes, M; Sundekilde, UK; Young, JF | 1 |
| Berge, RK; Hov, JR; Lappegård, KT; Nestvold, TK; Svardal, A; Thoresen, H; Trøseid, M | 1 |
| Dambrova, M; Erglis, A; Grinberga, S; Hartmane, D; Konrade, I; Kuka, J; Latkovskis, G; Liepinsh, E; Pugovics, O; Strele, I | 1 |
| Chmurzynska, A; Malinowska, AM; Szwengiel, A | 1 |
| Egert, B; Empl, MT; Frommherz, L; Krüger, R; Kulling, SE; Steinberg, P; Weinert, CH | 1 |
| Chen, MX; Lu, JQ; Nie, J; Wang, S; Xia, GH; Xu, KY; Yin, J; You, C; Zhen, X; Zhou, HW | 1 |
| Esteras, R; Fernandez-Prado, R; Gonzalez-Parra, E; Gracia-Iguacel, C; Ortiz, A; Perez-Gomez, MV; Sanchez-Niño, MD; Sanz, AB | 1 |
| Berge, RK; Haissman, JM; Haugaard, AK; Hov, JR; Nielsen, SD; Ostrowski, SR; Trøseid, M | 1 |
| Shimizu, M; Yamazaki, H | 1 |
| Li, DY; Tang, WHW | 1 |
| Grinberga, S; Hartmane, D; Kalnins, G; Sevostjanovs, E; Tars, K | 1 |
| Cai, W; Gao, J; Li, H; Li, Y; Ma, Y; Niu, X; Yang, G; Yang, N; Zhang, X; Zhao, Y; Zhou, X | 1 |
| Bray, GA; Heianza, Y; Qi, L; Sacks, FM; Smith, SR; Sun, D | 1 |
| Broniowska, K; Levy, HL; Murali, SG; Nair, N; Ney, DM; Rohr, F; Stroup, BM | 1 |
| Allayee, H; Buffa, JA; Cajka, T; DiDonato, JA; Fiehn, O; Gu, X; Han, Y; Hartiala, JA; Hazen, SL; Hurd, AG; Kerby, RL; Li, L; Li, XS; Lüscher, TF; Nemet, I; Obeid, S; Rey, FE; Roberts, AB; Romano, KA; Shahen, CJ; Skye, SM; Tang, WHW; Wagner, MA; Wang, Z; Wu, Y | 1 |
| Huet, B; Jialal, I; Lent-Schochet, D; McLaughlin, M; Silva, R | 1 |
| Bray, GA; DiDonato, JA; Heianza, Y; Li, X; Qi, L; Sacks, FM; Sun, D | 1 |
| Barlik, M; Chmurzynska, A; Drews, K; Jagodziński, PP; Kurzawińska, G; Malinowska, AM; Radziejewska, A; Różycka, A; Seremak-Mrozikiewicz, A; Szwengiel, A | 1 |
| Cai, Y; Guo, H; He, M; Hou, FF; Huo, Y; Li, GF; Li, Y; Liu, S; Nie, J; Qin, X; Qiu, B; Wang, B; Wang, Y; Xie, L; Xu, X; Zhang, H; Zhao, BX; Zhu, F | 1 |
| Chang, TY; Chen, CC; Chen, PC; Chen, RA; Chiu, THT; Chuang, HL; Ho, CT; Hsu, CC; Huang, YT; Kao, HL; Kuo, CH; Kuo, HC; Liao, BY; Lin, CL; Liu, PY; Panyod, S; Sheen, LY; Wu, MS; Wu, WK; Yu, HT; Zou, HB | 1 |
| Grinberga, S; Hartmane, D; Lysiak-Szydlowska, W; Olek, RA; Pugovics, O; Samulak, JJ; Sawicka, AK | 1 |
| Freeman, LM; Karlin, ET; Rush, JE | 1 |
| Bartlett, D; Cody, DB; Copeland, MF; Culley, MK; Dai, HJ; DiDonato, JA; Fu, X; Garcia-Garcia, JC; Gu, X; Hazen, SL; Kirsop, J; Koeth, RA; Lam-Galvez, BR; Levison, BS; Li, L; Li, XS; Tang, WHW; Wang, Z; Wu, Y | 1 |
| Arduini, A; Bonomini, M; Zammit, VA | 1 |
| Gloor, GB; Joris, BR | 1 |
| de Hora, M; Glamuzina, E; Knoll, D; Kyle, C; Webster, D; Wilson, C | 1 |
| Li, B; Li, C; Liu, J; Liu, Z; Yang, M; Zhang, Q; Zhao, P; Zhong, W; Zhong, Z | 1 |
| Sheen, LY; Wu, MS; Wu, WK | 1 |
| Crane, H; Deeks, SG; Drozd, D; Hsue, PY; Hunt, P; Ma, Y; Martin, J; Neilan, BD; Rahalkar, S; Scherzer, R; Sinha, A | 1 |
| Abbott, KA; Alburikan, KA; Alkofide, HA; Garg, ML; Kalagi, NA; Stojanovski, E | 1 |
| Abbasi, J | 1 |
| Olek, RA; Samborowska, E; Samulak, JJ; Sawicka, AK | 1 |
| Chen, PY; Ho, CT; Koh, YC; Li, S; Pan, MH; Wu, JC; Yang, MJ | 1 |
| Andreassen, AK; Arora, S; Aukrust, P; Berge, RK; Broch, K; Dellgren, G; Gude, E; Gullestad, L; Hov, JR; Karason, K; Mayerhofer, CCK; Svardal, A; Trøseid, M; Ueland, T | 1 |
| Bray, GA; Chen, Y; DiDonato, JA; Heianza, Y; LeBoff, MS; Li, X; Pei, X; Qi, L; Sacks, FM; Sun, D; Zhou, T | 1 |
| Chen, PY; Ho, CT; Kalyanam, N; Koh, YC; Li, S; Pan, MH; Wu, JC | 1 |
| Cao, YF; Fang, ZZ; Hu, G; Huo, X; Leng, J; Li, J; Li, SN; Li, W; Liu, J; Ma, RCW; Shao, P; Yang, K; Yang, X | 1 |
| Nowiński, A; Ufnal, M | 1 |
| Acikgoz, A; Berge, RK; Bjørndal, B; Caliskan Guzelce, E; Eyupoglu, ND; Svardal, A; Uyanik, E; Yildiz, BO | 1 |
| Giudetti, AM; Gnoni, A; Gnoni, GV; Longo, S | 1 |
| Cheng, I; Franke, AA; Fu, BC; Hullar, MAJ; Lampe, JW; Le Marchand, L; Lim, U; Madeleine, MM; Monroe, KR; Randolph, TW; Shepherd, JA; Wilkens, LR | 1 |
| Meyer, KA | 1 |
| Bellamine, A; Moré, M; Papandreou, C | 1 |
| Auger, J; Dahl, WJ; Ford, AL; Hung, WL; Nagulesapillai, V; Suh, JH; Wang, Y | 1 |
| Chi, N; Jiang, XM; Wang, YM; Xue, CH; Yu, ZL; Zhang, LY; Zhang, TT | 1 |
| García-Cañas, V; Simó, C | 1 |
| Hazen, SL; Weeks, TL; Witkowski, M | 1 |
| Gao, X; Randell, E; Sun, G; Tian, Y; Zhou, H | 1 |
| Chen, L; Chen, Y; Fan, D; Zhao, M; Zheng, L | 1 |
| Dai, Q; Guo, F; Liu, Y; Ouyang, D; Tan, Z; Zeng, X; Zhang, H | 1 |
| Olek, RA; Renzi, G; Sawicka, AK | 1 |
| Emoto, T; Hirata, KI; Yamashita, T; Yoshida, N | 1 |
| Aukrust, P; Berge, RK; Dahl, TB; Fevang, B; Halvorsen, B; Holm, K; Hov, JR; Jørgensen, SF; Kummen, M; Macpherson, ME; Mollnes, TE; Otterdal, K; Trøseid, M; Ueland, T | 1 |
| Chen, CC; Chen, YH; Chiu, THT; Chuang, HL; Chung, CH; Hsu, CC; Kao, HL; Kuo, CH; Kuo, HC; Lee, YC; Liao, BY; Lin, AY; Liu, PY; Orekhov, AN; Panyod, S; Sheen, LY; Tang, SL; Wang, JT; Wu, MS; Wu, WK; Wu, YW; Zou, HB | 1 |
| Alonso-Gómez, A; Bulló, M; Clish, C; Corella, D; Estruch, R; Fiol, M; Fitó, M; Guasch-Ferré, M; Hernández-Alonso, P; Hu, FB; Li, J; Liang, L; Martínez-González, MA; Papandreou, C; Ros, E; Ruiz-Canela, M; Salas-Salvadó, J; Santos-Lozano, JM; Serra-Majem, L; Toledo, E | 1 |
| Cao, W; Gao, M; Huang, T; Liu, Z; Yang, R; Zhuang, Z | 1 |
| Bernieh, D; Cassambai, S; Heaney, LM; Israr, MZ; Jones, DJL; Ng, LL; Salzano, A; Suzuki, T; Yazaki, Y | 1 |
| Angius, A; Baragetti, A; Caredda, G; Caruso, D; Catapano, AL; Cibella, J; Consolandi, C; Dioguardi, CC; Giavarini, F; Grigore, L; Mattavelli, E; Norata, GD; Olmastroni, E; Peano, C; Pellegatta, F; Rotta, L; Severgnini, M | 1 |
| Coutinho-Wolino, KS; de F Cardozo, LFM; de Oliveira Leal, V; Mafra, D; Stockler-Pinto, MB | 1 |
| Chen, GY; Chepyala, D; Chiu, HH; Kuo, CH; Kuo, HC; Lu, WH | 1 |
| Ding, YJ; Jia, QJ; Li, YY; Lv, SC; Wang, YJ; Zhang, A; Zhang, JP; Zhang, WQ; Zhang, XN; Zhu, YP | 1 |
| Dong, E; Gao, J; Huang, M; Ji, L; Li, C; Ni, L; Shen, X; Wang, DW; Wang, Z; Wei, H; Yu, T; Zhang, Q; Zhao, C; Zhao, M; Zheng, L | 1 |
| Bergström, M; Fagerström, C; Hefni, ME; Lennqvist, T; Witthöft, CM | 1 |
| Chen, R; Ren, D; Shi, L; Yang, X; Zhang, X; Zhao, Y | 1 |
| Lv, S; Shang, H; Wang, Y; Zhang, W | 1 |
| Al-Abbasi, FA; Alshehri, S; Bin-Jumah, MN; Ghoneim, MM; Gilani, SJ; Hosawi, S; Imam, SS; Kazmi, I; Nadeem, MS; Zeyadi, M | 1 |
| Bergeron, N; Buffa, JA; Cody, DB; Copeland, MF; Dai, HJ; DiDonato, JA; Dwidar, M; Ferrell, M; Fu, X; Galvez, R; Garcia-Garcia, JC; Gerberick, GF; Gogonea, V; Hajjar, AM; Hazen, SL; Hu, P; Koeth, RA; Krauss, RM; Li, L; Li, XS; McMillan, A; Nemet, I; Parlov, M; Rey, FE; Romano, KA; Sangwan, N; Skye, S; Tang, WHW; Wang, Z; Ward, K; Weeks, TL; Wei, X; Zhu, W | 1 |
| Amrein, M; Bakula, A; Ceresa, B; Glarner, N; Haaf, P; Hazen, SL; Honegger, U; Koechlin, L; Leu, K; Li, XS; Mueller, C; Nestelberger, T; Puelacher, C; Schäfer, I; Strebel, I; Twerenbold, R; Walter, J; Wang, Z; Zellweger, M; Zimmermann, T | 1 |
| Budoff, M; de Oliveira Otto, MC; DiDonato, JA; Fretts, AM; Hazen, SL; Jensen, P; Lai, H; Lee, Y; Lemaitre, RN; Mozaffarian, D; Psaty, BM; Siscovick, DS; Sitlani, CM; Sotoodehnia, N; Tang, WHW; Wang, M | 1 |
| Chen, B; Fu, Q; Wei, S; Xiong, X; Xu, X; Yang, S; Zhou, J | 1 |
| Budoff, M; de Oliveira Otto, MC; DiDonato, JA; Fretts, A; Hazen, SL; Lai, HTM; Lee, Y; Lemaitre, RN; McKnight, B; Mozaffarian, D; Psaty, BM; Siscovick, DS; Sotoodehnia, N; Tang, WHW; Wang, M; Wang, Z | 1 |
| Anand, N; Chandana, KA; Chidambaram, SB; Kalyan, M; Kanna, PV; Mahalakshmi, AM; Pandi-Perumal, SR; Praveenraj, SS; Sakharkar, MK; Shasthara, P; Sonali, S; Tousif, HA; Vichitra, C; Yang, J | 1 |
| de Oliveira Otto, MC; Fretts, A; Hazen, SL; Lai, HTM; Lee, Y; Lemaitre, RN; Li, XS; Lopez, O; Mozaffarian, D; Nemet, I; Newman, AB; Siscovick, DS; Tang, WHW; Wang, M; Wang, Z | 1 |
| Dong, E; Gao, J; Huang, M; Ji, L; Li, C; Wang, DW; Wang, Y; Wei, H; Wu, J; Zhang, Q; Zhao, C; Zhao, M; Zheng, L | 1 |
| Gu, S; Liu, D; Ma, Z; Zhou, Z; Zuo, H | 1 |
| Brzeska, B; Jaworska, J; Olek, RA; Radkiewicz, M; Sabisz, A; Samborowska, E; Sawicka, AK; Szarmach, A; Szurowska, E; Winklewski, PJ | 1 |
| Blanco, R; Daimiel, L; Dávalos, A; Díez-Ricote, L; Micó, V; Ordovás, JM; Ruiz-Valderrey, P; Tomé-Carneiro, J | 1 |
| Gao, X; Hu, S; Li, D; Sun, C; Zhang, Y | 1 |
| Becerra-Muñoz, VM; Crespo-Leiro, MG; Delgado, J; Estévez, M; Jiménez-Navarro, MF; Medina-Vera, D; Pavón-Morón, FJ; Plaza-Andrades, I; Queipo-Ortuño, MI; Rodríguez-Capitán, J; Sánchez, PL; Sánchez-Quintero, MJ | 1 |
| Wang, N; Wu, Q; Yang, X; Zhang, L; Zhao, Y | 1 |
| Lazar, M; Olma, A; Streb, W | 1 |
| Ament, Z; Bevers, MB; Bhave, VM; Couch, CA; Garcia Guarniz, AL; Irvin, MR; Kijpaisalratana, N; Kimberly, WT | 1 |
20 review(s) available for carnitine and trimethyloxamine
| Article | Year |
|---|---|
Gut microbiota metabolism of L-carnitine and cardiovascular risk.
Topics: Animals; Atherosclerosis; Cardiovascular Diseases; Carnitine; Diet; Dietary Supplements; Humans; Insulin Resistance; Intestines; Liver; Methylamines; Mice; Microbiota; Muscle, Skeletal; Myocardial Ischemia; Phosphatidylcholines; Risk | 2013 |
Metaorganismal nutrient metabolism as a basis of cardiovascular disease.
Topics: Animals; Atherosclerosis; Cardiovascular Diseases; Carnitine; Diet; Humans; Methylamines; Risk | 2014 |
The contributory role of gut microbiota in cardiovascular disease.
Topics: Animals; Atherosclerosis; Cardiovascular Diseases; Carnitine; Choline; Diet; Female; Food; Humans; Intestines; Male; Methylamines; Microbiota; Oxygenases; Phosphatidylcholines | 2014 |
New aspects on the metabolic role of intestinal microbiota in the development of atherosclerosis.
Topics: Animals; Atherosclerosis; Betaine; Carnitine; Choline; Humans; Intestinal Mucosa; Intestines; Methylamines; Microbiota; Phosphatidylcholines | 2015 |
Trimethylamine N-Oxide From Gut Microbiota in Chronic Kidney Disease Patients: Focus on Diet.
Topics: Animals; Cardiovascular Diseases; Carnitine; Choline; Diet, Protein-Restricted; Disease Models, Animal; Eggs; Gastrointestinal Microbiome; Humans; Methylamines; Randomized Controlled Trials as Topic; Red Meat; Renal Insufficiency, Chronic | 2015 |
Nutrients Turned into Toxins: Microbiota Modulation of Nutrient Properties in Chronic Kidney Disease.
Topics: Cardiovascular Diseases; Carnitine; Choline; Diet; Gastrointestinal Microbiome; Humans; Methylamines; Micronutrients; Oxalates; Phosphates; Phosphatidylcholines; Renal Insufficiency, Chronic; Tryptophan; Tyrosine | 2017 |
Gut Microbiota and Atherosclerosis.
Topics: Animals; Atherosclerosis; Bile Acids and Salts; Carnitine; Diet; Disease Models, Animal; Gastrointestinal Microbiome; Humans; Methylamines | 2017 |
Unaccounted risk of cardiovascular disease: the role of the microbiome in lipid metabolism.
Topics: Animals; Atherosclerosis; Bile Acids and Salts; Carnitine; Choline; Energy Metabolism; Fatty Acids, Volatile; Gastrointestinal Microbiome; Genomics; High-Throughput Nucleotide Sequencing; Humans; Lipid Metabolism; Metabolic Syndrome; Methylamines; Phosphatidylcholines; RNA, Ribosomal, 16S; T-Lymphocytes, Helper-Inducer; Triglycerides | 2019 |
The decision to discontinue screening for carnitine uptake disorder in New Zealand.
Topics: Animals; Atherosclerosis; Biological Transport; Carnitine; Humans; Infant, Newborn; Methylamines; Neonatal Screening; New Zealand | 2019 |
Modulation of Circulating Trimethylamine N-Oxide Concentrations by Dietary Supplements and Pharmacological Agents: A Systematic Review.
Topics: Anti-Bacterial Agents; Antioxidants; Cardiovascular Diseases; Carnitine; Choline; Dietary Supplements; Gastrointestinal Microbiome; Humans; Methylamines; Prebiotics; Probiotics; Risk Factors | 2019 |
Carnitine in Human Muscle Bioenergetics: Can Carnitine Supplementation Improve Physical Exercise?
Topics: Carnitine; Carnitine O-Palmitoyltransferase; Dietary Supplements; Energy Metabolism; Exercise; Fatty Acids; Humans; Methylamines; Mitochondria; Muscle, Skeletal; Oxidation-Reduction | 2020 |
Trimethylamine N-Oxide in Relation to Cardiometabolic Health-Cause or Effect?
Topics: Age Factors; Amines; Animals; Cardiometabolic Risk Factors; Cardiovascular Diseases; Carnitine; Digestion; Disease Models, Animal; Eating; Female; Fishes; Gastrointestinal Microbiome; Humans; Male; Meat; Methylamines; Mice; Sex Characteristics | 2020 |
Dietary bioactive ingredients to modulate the gut microbiota-derived metabolite TMAO. New opportunities for functional food development.
Topics: Betaine; Biological Availability; Carnitine; Choline; Diet; Food Ingredients; Functional Food; Gastrointestinal Absorption; Gastrointestinal Microbiome; Gastrointestinal Tract; Heart Disease Risk Factors; Humans; Liver; Methylamines; Oxygenases | 2020 |
Gut Microbiota and Cardiovascular Disease.
Topics: Animals; Atherosclerosis; Bile Acids and Salts; Cardiovascular Diseases; Carnitine; Choline; Disease Models, Animal; Fatty Acids, Volatile; Fecal Microbiota Transplantation; Feces; Gastrointestinal Microbiome; Glutamine; Host Microbial Interactions; Humans; Methylamines; Mice; Mice, Inbred C57BL; Signal Transduction; Thrombosis; Vasculitis | 2020 |
The bright and the dark sides of L-carnitine supplementation: a systematic review.
Topics: Age Factors; Body Composition; Carnitine; Cognition; Dietary Carbohydrates; Dietary Supplements; Energy Metabolism; Exercise; Exercise Tolerance; Humans; Lipid Metabolism; Methylamines; Muscle Proteins; Muscle Strength; Muscle, Skeletal; Obesity; Oxidation-Reduction; Physical Conditioning, Human; Sarcopenia | 2020 |
Can diet modulate trimethylamine N-oxide (TMAO) production? What do we know so far?
Topics: Carnitine; Choline; Diet; Gastrointestinal Microbiome; Methylamines | 2021 |
TMA/TMAO in Hypertension: Novel Horizons and Potential Therapies.
Topics: Animals; Carnitine; Choline; Gastrointestinal Microbiome; Glucose; Humans; Hypertension; Inflammation; Lipid Metabolism; Methylamines | 2021 |
Trimethylamine oxide: a potential target for heart failure therapy.
Topics: Cardiotonic Agents; Carnitine; Choline; Diuretics; Gastrointestinal Microbiome; Heart Failure; Humans; Methylamines | 2022 |
Pathobiological Relationship of Excessive Dietary Intake of Choline/L-Carnitine: A TMAO Precursor-Associated Aggravation in Heart Failure in Sarcopenic Patients.
Topics: Biodiversity; Biomarkers; Carnitine; Choline; Dietary Supplements; Disease Susceptibility; Dysbiosis; Gastrointestinal Microbiome; Heart Failure; Humans; Methylamines; Sarcopenia | 2021 |
The Role of a Gut Microbial-Derived Metabolite, Trimethylamine N-Oxide (TMAO), in Neurological Disorders.
Topics: Betaine; Carnitine; Choline; Flavins; Gastrointestinal Microbiome; Humans; Inflammasomes; Lyases; Methylamines; Mixed Function Oxygenases; Nervous System Diseases; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein | 2022 |
13 trial(s) available for carnitine and trimethyloxamine
| Article | Year |
|---|---|
Disposition and metabolite kinetics of oral L-carnitine in humans.
Topics: Administration, Oral; Adult; Area Under Curve; Carnitine; Chromatography, High Pressure Liquid; Diarrhea; Dose-Response Relationship, Drug; Humans; Kidney; Male; Metabolic Clearance Rate; Methylamines; Nausea; Taste Disorders; Vitamin B Complex | 2006 |
Oral L-carnitine: metabolite formation and hemodialysis.
Topics: Administration, Oral; Adult; Aged; Carnitine; Humans; Kidney Failure, Chronic; Male; Methylamines; Middle Aged; Renal Dialysis | 2006 |
Meldonium decreases the diet-increased plasma levels of trimethylamine N-oxide, a metabolite associated with atherosclerosis.
Topics: Adult; Atherosclerosis; Cardiovascular Agents; Carnitine; Diet; Female; HEK293 Cells; Humans; Male; Methylamines; Methylhydrazines; Organic Cation Transport Proteins; Seafood; Solute Carrier Family 22 Member 5 | 2013 |
Probiotic supplementation and trimethylamine-N-oxide production following a high-fat diet.
Topics: Adolescent; Adult; Betaine; Carnitine; Choline; Diet, High-Fat; Dietary Supplements; Fasting; Humans; Male; Methylamines; Probiotics; Tandem Mass Spectrometry; Young Adult | 2015 |
Krill oil reduces plasma triacylglycerol level and improves related lipoprotein particle concentration, fatty acid composition and redox status in healthy young adults - a pilot study.
Topics: Adolescent; Adult; Animals; Atherosclerosis; Betaine; Carnitine; Choline; Chylomicrons; Cytokines; Dietary Fats, Unsaturated; Docosahexaenoic Acids; Eicosapentaenoic Acid; Erythrocytes; Euphausiacea; Fatty Acids, Unsaturated; Female; Humans; Lipoproteins, VLDL; Male; Methylamines; Particle Size; Pilot Projects; Triglycerides | 2015 |
Lean-seafood intake decreases urinary markers of mitochondrial lipid and energy metabolism in healthy subjects: Metabolomics results from a randomized crossover intervention study.
Topics: Adolescent; Adult; Aged; Biomarkers; Carnitine; Cross-Over Studies; Diet; Dietary Proteins; Energy Metabolism; Female; Glycine; Healthy Volunteers; Humans; Lipid Metabolism; Male; Metabolomics; Methylamines; Methylhistidines; Middle Aged; Mitochondria; Pyridones; Seafood; Young Adult | 2016 |
Changes in Gut Microbiota-Related Metabolites and Long-term Successful Weight Loss in Response to Weight-Loss Diets: The POUNDS Lost Trial.
Topics: Adipose Tissue, White; Adiposity; Adult; Body Weight; Caloric Restriction; Carnitine; Choline; Diabetes Mellitus, Type 2; Diet, Reducing; Energy Metabolism; Female; Gastrointestinal Microbiome; Humans; Male; Methylamines; Middle Aged; Obesity; Treatment Outcome; Waist Circumference; Weight Loss | 2018 |
Metabolomic Markers of Essential Fatty Acids, Carnitine, and Cholesterol Metabolism in Adults and Adolescents with Phenylketonuria.
Topics: Adolescent; Adult; Amino Acids; Betaine; Biomarkers; Carnitine; Caseins; Cholesterol; Cross-Over Studies; Dietary Supplements; Erythrocytes; Fasting; Fatty Acids; Fatty Acids, Essential; Female; Gastrointestinal Microbiome; Humans; Lipid Metabolism; Male; Metabolomics; Methylamines; Middle Aged; Peptide Fragments; Phenylketonurias | 2018 |
Gut microbiota metabolites, amino acid metabolites and improvements in insulin sensitivity and glucose metabolism: the POUNDS Lost trial.
Topics: Adult; Amino Acids; Carnitine; Choline; Diet, Reducing; Female; Gastrointestinal Microbiome; Glucose; Humans; Insulin Resistance; Male; Massachusetts; Methylamines; Obesity; Overweight | 2019 |
l-Carnitine in omnivorous diets induces an atherogenic gut microbial pathway in humans.
Topics: Animals; Atherosclerosis; Betaine; Carnitine; Clostridiales; Female; Gastrointestinal Microbiome; Humans; Male; Methylamines; Mice; Pilot Projects; Vegans | 2019 |
Circulating Gut Microbiota Metabolite Trimethylamine N-Oxide (TMAO) and Changes in Bone Density in Response to Weight Loss Diets: The POUNDS Lost Trial.
Topics: Absorptiometry, Photon; Adult; Bone Density; Carnitine; Choline; Diabetes Mellitus, Type 2; Diet, Reducing; Dietary Fats; Female; Gastrointestinal Microbiome; Humans; Male; Methylamines; Middle Aged; Nutritional Status; Obesity; Overweight; Weight Loss | 2019 |
In older women, a high-protein diet including animal-sourced foods did not impact serum levels and urinary excretion of trimethylamine-N-oxide.
Topics: Aged; Carnitine; Clostridiales; Cresols; Cross-Over Studies; Diet, High-Protein; Feces; Female; Gastrointestinal Microbiome; Glutamine; Humans; Indican; Meat; Methylamines; Prebiotics; Probiotics; Sulfuric Acid Esters; Synbiotics | 2020 |
Characterization of TMAO productivity from carnitine challenge facilitates personalized nutrition and microbiome signatures discovery.
Topics: Administration, Oral; Adult; Animals; Carnitine; Clostridiales; Female; Humans; Male; Methylamines; Mice; Microbiota | 2020 |
79 other study(ies) available for carnitine and trimethyloxamine
| Article | Year |
|---|---|
L-carnitine protects fish against acute ammonia toxicity.
Topics: Acetates; Animals; Carnitine; Methylamines; Salmon | 1992 |
Quantitative estimation of absorption and degradation of a carnitine supplement by human adults.
Topics: Absorption; Administration, Oral; Adult; Betaine; Carnitine; Chromatography, Ion Exchange; Feces; Humans; Male; Methylamines; Scintillation Counting | 1991 |
Metabolic fate of dietary carnitine in human adults: identification and quantification of urinary and fecal metabolites.
Topics: Adult; Betaine; Biotransformation; Carnitine; Chromatography, Ion Exchange; Diet; Feces; Humans; Male; Methylamines; Scintillation Counting; Tritium | 1991 |
Protection against acute hyperammonemia: the role of quaternary amines.
Topics: Acetates; Ammonia; Animals; Betaine; Carnitine; Choline; Glutamates; Glutamic Acid; Glutamine; Male; Methylamines; Mice | 1988 |
Chromatographic separation of choline, trimethylamine, trimethylamine oxide, and betaine from tissues of marine fish.
Topics: Animals; Betaine; Carnitine; Choline; Chromatography, Ion Exchange; Fishes; Liver; Methylamines; Muscles; Tissue Extracts | 1984 |
Disposition of L-carnitine and acetyl-L-carnitine in the isolated perfused rat kidney.
Topics: Acetylcarnitine; Animals; Carnitine; Drug Interactions; In Vitro Techniques; Kidney Tubules; Male; Methylamines; Oxidants; Perfusion; Rats; Rats, Sprague-Dawley | 1995 |
[TRIMETHYLAMINE AND TRIMETHYLAMINE OXIDE IN THE URINE AFTER THE ADMINISTRATION OF N-14- AND N-15-(-) CARNITINE].
Topics: Amines; Body Fluids; Carnitine; Folic Acid; Humans; Hyperthyroidism; Male; Methylamines; Nitrogen; Prostatic Neoplasms; Radioisotopes; Urine; Vitamin B Complex | 1963 |
Susceptibility of human metabolic phenotypes to dietary modulation.
Topics: Acetylcarnitine; Adult; Aged; Carnitine; Creatine; Diet; Diet, Vegetarian; Feeding Behavior; Humans; Magnetic Resonance Spectroscopy; Male; Meat; Metabolism; Methylamines; Middle Aged; Phenotype; Phenylacetates | 2006 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; Macrophages; Mass Spectrometry; Meat; Metagenome; Methylamines; Mice; Mice, Knockout; RNA; Time Factors | 2013 |
Risk factors for cardiovascular disease: a cautionary tale of diet-microbiome interactions.
Topics: Cardiovascular Diseases; Carnitine; Choline; Diet; Gastrointestinal Tract; Humans; Methylamines; Microbiota; Risk Factors | 2013 |
Urinary metabolomic changes as a predictive biomarker of asthma exacerbation.
Topics: Adult; Aged; Asthma; Biomarkers; Carnitine; Cohort Studies; Disease Progression; Female; Gas Chromatography-Mass Spectrometry; Humans; Magnetic Resonance Spectroscopy; Male; Metabolomics; Methylamines; Middle Aged; Oxidative Stress; Pilot Projects; Prospective Studies; Threonine | 2014 |
Comparative genome-wide association studies in mice and humans for trimethylamine N-oxide, a proatherogenic metabolite of choline and L-carnitine.
Topics: Aged; Animals; Carnitine; Cation Transport Proteins; Choline; Chromosomes, Human, Pair 1; Female; Genome-Wide Association Study; Humans; Male; Methylamines; Mice; Middle Aged; Multigene Family; Oxygenases; Polymorphism, Single Nucleotide | 2014 |
Suppression of intestinal microbiota-dependent production of pro-atherogenic trimethylamine N-oxide by shifting L-carnitine microbial degradation.
Topics: Animals; Betaine; Biosynthetic Pathways; Carbon Isotopes; Carnitine; Choline; Chromatography, High Pressure Liquid; Gastrointestinal Tract; Methylamines; Methylhydrazines; Microbiota; Rats; Rats, Wistar; Statistics, Nonparametric; Tandem Mass Spectrometry | 2014 |
γ-Butyrobetaine is a proatherogenic intermediate in gut microbial metabolism of L-carnitine to TMAO.
Topics: Animals; Atherosclerosis; Betaine; Carnitine; Female; Gastrointestinal Tract; Methylamines; Mice; Mice, Inbred C57BL; Microbiota | 2014 |
Oral L-carnitine supplementation increases trimethylamine-N-oxide but reduces markers of vascular injury in hemodialysis patients.
Topics: Administration, Oral; Aged; Biomarkers; Carnitine; Case-Control Studies; Deficiency Diseases; Dietary Supplements; Female; Glycation End Products, Advanced; Humans; Intercellular Adhesion Molecule-1; Japan; Kidney Diseases; Male; Malondialdehyde; Methylamines; Middle Aged; Oxidative Stress; Renal Dialysis; Time Factors; Treatment Outcome; Vascular Cell Adhesion Molecule-1; Vascular System Injuries | 2015 |
Determination of trimethylamine-N-oxide in combination with L-carnitine and γ-butyrobetaine in human plasma by UPLC/MS/MS.
Topics: Betaine; Carnitine; Chromatography, Liquid; Humans; Limit of Detection; Methylamines; Reference Standards; Reproducibility of Results; Tandem Mass Spectrometry | 2015 |
Short-term high-fat diet increases postprandial trimethylamine-N-oxide in humans.
Topics: Adolescent; Adult; Betaine; Carnitine; Choline; Diet, Atherogenic; Diet, High-Fat; Fasting; Gastrointestinal Microbiome; Humans; Male; Methylamines; Oxidants; Postprandial Period; Young Adult | 2015 |
A Phospholipid-Protein Complex from Antarctic Krill Reduced Plasma Homocysteine Levels and Increased Plasma Trimethylamine-N-Oxide (TMAO) and Carnitine Levels in Male Wistar Rats.
Topics: Animal Feed; Animals; Carnitine; Diet; Dietary Proteins; Euphausiacea; Homocysteine; Male; Methionine; Methylamines; Phospholipids; Rats; Rats, Wistar | 2015 |
L-Carnitine intake and high trimethylamine N-oxide plasma levels correlate with low aortic lesions in ApoE(-/-) transgenic mice expressing CETP.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Carnitine; Cells, Cultured; Cholesterol Ester Transfer Proteins; Disease Models, Animal; Disease Progression; Humans; Macrophages; Male; Methylamines; Mice; Mice, Knockout | 2016 |
The Carnitine-butyrobetaine-trimethylamine-N-oxide pathway and its association with cardiovascular mortality in patients with carotid atherosclerosis.
Topics: Aged; Betaine; Biomarkers; Carnitine; Carotid Stenosis; Case-Control Studies; Cause of Death; Chromatography, High Pressure Liquid; Female; Humans; Kaplan-Meier Estimate; Lysine; Male; Methylamines; Middle Aged; Myocardial Infarction; Prognosis; Proportional Hazards Models; Risk Assessment; Risk Factors; Severity of Illness Index; Stroke; Ultrasonography, Doppler, Color | 2016 |
Major Increase in Microbiota-Dependent Proatherogenic Metabolite TMAO One Year After Bariatric Surgery.
Topics: Adult; Atherosclerosis; Bariatric Surgery; Betaine; Body Mass Index; Cardiovascular Diseases; Carnitine; Case-Control Studies; Choline; Chromatography, High Pressure Liquid; Diabetes Complications; Diabetes Mellitus, Type 2; Female; Humans; Life Style; Male; Methylamines; Microbiota; Middle Aged; Obesity; Postoperative Period; Time Factors | 2016 |
Diabetes is Associated with Higher Trimethylamine N-oxide Plasma Levels.
Topics: Age Factors; Aged; Animals; Body Mass Index; Cardiovascular Diseases; Carnitine; Diabetes Mellitus; Disease Models, Animal; Female; Humans; Male; Methylamines; Mice; Middle Aged | 2016 |
Dietary, anthropometric, and biochemical factors influencing plasma choline, carnitine, trimethylamine, and trimethylamine-N-oxide concentrations.
Topics: Aged; Body Size; Carnitine; Choline; Diet; Female; Humans; Methylamines; Middle Aged | 2017 |
The influence of a chronic L-carnitine administration on the plasma metabolome of male Fischer 344 rats.
Topics: Animals; Carcinogens; Cardiovascular Diseases; Carnitine; Dietary Supplements; Dose-Response Relationship, Drug; Male; Metabolome; Metabolomics; Methylamines; Rats; Rats, Inbred F344; Tandem Mass Spectrometry | 2017 |
Impaired renal function and dysbiosis of gut microbiota contribute to increased trimethylamine-N-oxide in chronic kidney disease patients.
Topics: Adult; Aged; Animals; Betaine; Carnitine; Case-Control Studies; Choline; Clostridiaceae; Dysbiosis; Fecal Microbiota Transplantation; Female; Gammaproteobacteria; Gastrointestinal Microbiome; High-Throughput Nucleotide Sequencing; Humans; Kidney Function Tests; Male; Methylamines; Mice; Mice, Inbred C57BL; Middle Aged; Renal Insufficiency, Chronic | 2017 |
Microbiota-dependent metabolite and cardiovascular disease marker trimethylamine-N-oxide (TMAO) is associated with monocyte activation but not platelet function in untreated HIV infection.
Topics: Adult; Betaine; Biomarkers; Blood Platelets; Cardiovascular Diseases; Carnitine; Choline; Cross-Sectional Studies; Female; HIV Infections; Humans; Lipopolysaccharide Receptors; Male; Methylamines; Microbiota; Middle Aged; Monocytes; Myocardial Infarction; Platelet Aggregation; Risk Factors | 2017 |
Human plasma and urinary metabolic profiles of trimethylamine and trimethylamine N-oxide extrapolated using a simple physiologically based pharmacokinetic model.
Topics: Administration, Oral; Animals; Carnitine; Humans; In Vitro Techniques; Kidney; Male; Methylamines; Microsomes, Liver; Models, Biological; Rats; Rats, Sprague-Dawley; Risk Assessment | 2017 |
CntA oxygenase substrate profile comparison and oxygen dependency of TMA production in Providencia rettgeri.
Topics: Carnitine; Humans; Methylamines; Microbiota; Oxidation-Reduction; Oxygen; Oxygenases; Providencia; Substrate Specificity | 2018 |
The Effect of Different l-Carnitine Administration Routes on the Development of Atherosclerosis in ApoE Knockout Mice.
Topics: Administration, Oral; Animals; Apolipoproteins E; Atherosclerosis; Carnitine; Diet, High-Fat; Humans; Injections, Subcutaneous; Lipids; Methylamines; Mice; Mice, Knockout; Monocytes; Oxygenases | 2018 |
Untargeted metabolomics identifies trimethyllysine, a TMAO-producing nutrient precursor, as a predictor of incident cardiovascular disease risk.
Topics: Aged; Animals; Atherosclerosis; Cardiovascular Diseases; Carnitine; Cholesterol; Choline; Disease Models, Animal; Feces; Female; Gastrointestinal Microbiome; Genome-Wide Association Study; Humans; Lysine; Male; Metabolomics; Methylamines; Mice; Mice, Inbred C57BL; Middle Aged; Nutrients; Risk Factors; Thrombosis | 2018 |
Changes to trimethylamine-N-oxide and its precursors in nascent metabolic syndrome.
Topics: Adult; Aged; Biomarkers; Carnitine; Choline; Female; Humans; Inflammation; Male; Metabolic Syndrome; Methylamines; Middle Aged; Young Adult | 2018 |
PEMT rs12325817 and PCYT1A rs7639752 polymorphisms are associated with betaine but not choline concentrations in pregnant women.
Topics: Adolescent; Adult; Alleles; Betaine; Birth Weight; Carnitine; Choline; Choline-Phosphate Cytidylyltransferase; Diet; Female; Folic Acid; Genotype; Homozygote; Humans; Infant, Newborn; Methylamines; Nutritional Status; Phosphatidylethanolamine N-Methyltransferase; Poland; Polymorphism, Single Nucleotide; Pregnancy; Pregnancy Complications; Young Adult | 2018 |
Serum Trimethylamine N-Oxide Concentration Is Positively Associated With First Stroke in Hypertensive Patients.
Topics: Aged; Carnitine; Case-Control Studies; China; Choline; Female; Folic Acid; Gastrointestinal Microbiome; Humans; Hypertension; Male; Methylamines; Middle Aged; Odds Ratio; Stroke | 2018 |
Identification of TMAO-producer phenotype and host-diet-gut dysbiosis by carnitine challenge test in human and germ-free mice.
Topics: Animals; Cardiovascular Diseases; Carnitine; Diet; Dysbiosis; Feeding Behavior; Gastrointestinal Microbiome; Humans; Methylamines; Mice; Oxidants; Prognosis; Renal Elimination | 2019 |
L-Carnitine Supplementation Increases Trimethylamine-N-Oxide but not Markers of Atherosclerosis in Healthy Aged Women.
Topics: Aged; Atherosclerosis; Biomarkers; Carnitine; Cholesterol; Dietary Supplements; Female; Humans; Methylamines; Triglycerides | 2019 |
A pilot study investigating circulating trimethylamine N-oxide and its precursors in dogs with degenerative mitral valve disease with or without congestive heart failure.
Topics: Animals; Carnitine; Case-Control Studies; Choline; Cross-Sectional Studies; Dog Diseases; Dogs; Echocardiography; Female; Heart Failure; Male; Methylamines; Mitral Valve Insufficiency; Pilot Projects | 2019 |
Identification of trimethylamine N-oxide (TMAO)-producer phenotype is interesting, but is it helpful?
Topics: Animals; Carnitine; Diet; Dysbiosis; Humans; Methylamines; Mice; Phenotype | 2020 |
Targeted metabolomic analysis of plasma metabolites in patients with coronary heart disease in southern China.
Topics: Aged; Angina, Stable; Angina, Unstable; Biomarkers; Carnitine; China; Choline; Chromatography, Liquid; Creatinine; Female; Humans; Male; Metabolomics; Methylamines; Middle Aged; Myocardial Infarction; Prospective Studies; Reproducibility of Results; ROC Curve; Tandem Mass Spectrometry | 2019 |
Response to the letter: Identification of trimethylamine N-oxide (TMAO)-producer phenotype is interesting, but is it helpful?
Topics: Animals; Carnitine; Diet; Dysbiosis; Humans; Methylamines; Mice; Phenotype | 2020 |
Carnitine Is Associated With Atherosclerotic Risk and Myocardial Infarction in HIV -Infected Adults.
Topics: Adult; Antiretroviral Therapy, Highly Active; Atherosclerosis; Betaine; Carnitine; Carotid Artery Diseases; Carotid Intima-Media Thickness; Choline; Female; Gastrointestinal Microbiome; HIV Infections; Humans; Male; Methylamines; Middle Aged; Myocardial Infarction; Plaque, Atherosclerotic; Sustained Virologic Response; United States | 2019 |
TMAO and Heart Disease: The New Red Meat Risk?
Topics: Cardiovascular Diseases; Carnitine; Diet; Fatty Acids; Gastrointestinal Microbiome; Humans; Methylamines; Red Meat | 2019 |
Plasma Trimethylamine-N-oxide following Cessation of L-carnitine Supplementation in Healthy Aged Women.
Topics: Aged; Atherosclerosis; Biomarkers; Carnitine; Dietary Supplements; Female; Follow-Up Studies; Healthy Volunteers; Humans; Leukocyte Count; Lipids; Methylamines; Muscle, Skeletal; Time Factors; Withholding Treatment | 2019 |
Oolong Tea Extract and Citrus Peel Polymethoxyflavones Reduce Transformation of l-Carnitine to Trimethylamine-
Topics: Animals; Atherosclerosis; Bacteria; Biotransformation; Camellia sinensis; Carnitine; Citrus; Female; Flavones; Gastrointestinal Microbiome; Gastrointestinal Tract; Humans; Methylamines; Mice; Mice, Inbred C57BL; Plant Extracts; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2019 |
The carnitine-butyrobetaine-TMAO pathway after cardiac transplant: Impact on cardiac allograft vasculopathy and acute rejection.
Topics: Acute Disease; Adult; Aged; Betaine; Carnitine; Coronary Artery Disease; Cyclosporine; Everolimus; Female; Graft Rejection; Heart Transplantation; Humans; Immunosuppressive Agents; Male; Methylamines; Microbiota; Middle Aged; Postoperative Complications | 2019 |
Prevention of Vascular Inflammation by Pterostilbene via Trimethylamine-N-Oxide Reduction and Mechanism of Microbiota Regulation.
Topics: Animals; Carnitine; Female; Gastrointestinal Microbiome; Methylamines; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Oxygenases; Stilbenes; Tumor Necrosis Factor-alpha; Vasculitis | 2019 |
Trimethylamine N-Oxide Metabolites in Early Pregnancy and Risk of Gestational Diabetes: A Nested Case-Control Study.
Topics: Adult; Betaine; Blood Glucose; Carnitine; Case-Control Studies; China; Choline; Diabetes, Gestational; Female; Humans; Methylamines; Pregnancy; Prenatal Care; Risk Factors | 2019 |
Is increased plasma TMAO a compensatory response to hydrostatic and osmotic stress in cardiovascular diseases?
Topics: Animals; Cardiovascular Diseases; Cardiovascular System; Carnitine; Choline; Diet; Humans; Hydrostatic Pressure; Kidney; Liver; Methylamines; Mice; Models, Theoretical; Osmotic Pressure; Rats; Risk Factors | 2019 |
Circulating gut microbiota metabolite trimethylamine N-oxide and oral contraceptive use in polycystic ovary syndrome.
Topics: Adolescent; Adult; Betaine; Blood Glucose; Cardiovascular Diseases; Carnitine; Choline; Female; Gastrointestinal Microbiome; Humans; Methylamines; Obesity; Polycystic Ovary Syndrome; Prospective Studies; Risk Factors; Testosterone; Young Adult | 2019 |
Associations of plasma trimethylamine N-oxide, choline, carnitine, and betaine with inflammatory and cardiometabolic risk biomarkers and the fecal microbiome in the Multiethnic Cohort Adiposity Phenotype Study.
Topics: Adiposity; Aged; Bacteria; Betaine; Biomarkers; Cardiovascular Diseases; Carnitine; Choline; Cohort Studies; Cross-Sectional Studies; Female; Gastrointestinal Microbiome; Humans; Male; Methylamines; Middle Aged | 2020 |
Population studies of TMAO and its precursors may help elucidate mechanisms.
Topics: Adiposity; Betaine; Biomarkers; Cardiovascular Diseases; Carnitine; Choline; Humans; Methylamines; Microbiota; Phenotype | 2020 |
Effects of dietary choline, betaine, and L-carnitine on the generation of trimethylamine-N-oxide in healthy mice.
Topics: Animals; Betaine; Carnitine; Choline; Female; Gastrointestinal Microbiome; Intestines; Male; Methylamines; Mice; Mice, Inbred BALB C | 2020 |
Systematic investigation of the relationships of trimethylamine
Topics: Adipocytes; Adipose Tissue, White; Adult; Animals; Body Composition; Body Weight; Carnitine; Diet, High-Fat; Female; Gene Expression; Humans; Lipogenesis; Lipolysis; Liver; Male; Methylamines; Mice; Mice, Inbred C57BL; Middle Aged; Obesity; RNA, Messenger | 2020 |
Changes in the concentrations of trimethylamine N-oxide (TMAO) and its precursors in patients with amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Betaine; Carnitine; Choline; Female; Gastrointestinal Microbiome; Humans; Male; Methylamines; Middle Aged; Motor Neurons; Prognosis; Signal Transduction | 2020 |
Renal function is associated with plasma trimethylamine-N-oxide, choline, L-carnitine and betaine: a pilot study.
Topics: Betaine; Biomarkers; Carnitine; Choline; Female; Glomerular Filtration Rate; Humans; Kidney; Male; Methylamines; Middle Aged; Pilot Projects; Renal Insufficiency, Chronic; Retrospective Studies | 2021 |
Unraveling the Effects of Trimethylamine N-Oxide on Stroke: "The lower, the better?"
Topics: Betaine; Carnitine; Cholesterol; Choline; Diet Therapy; Gastrointestinal Microbiome; Humans; Ischemic Stroke; Lipotropic Agents; Liver; Methylamines; Oxidants; Risk Factors | 2021 |
Gut Microbiota-Dependent Trimethylamine N-Oxide Associates With Inflammation in Common Variable Immunodeficiency.
Topics: Adult; Bacteria; Bacterial Proteins; Biomarkers; Carnitine; Common Variable Immunodeficiency; Diet; Feces; Female; Gastrointestinal Microbiome; Humans; Immunoglobulin A, Secretory; Inflammation; Lipopolysaccharides; Male; Metabolic Networks and Pathways; Methylamines; Middle Aged; Rifaximin | 2020 |
Choline Metabolism and Risk of Atrial Fibrillation and Heart Failure in the PREDIMED Study.
Topics: Aged; Atrial Fibrillation; Betaine; Carnitine; Case-Control Studies; Choline; Female; Heart Failure; Humans; Male; Methylamines; Prospective Studies; Risk Factors; Sarcosine | 2021 |
Causal relationships between gut metabolites and Alzheimer's disease: a bidirectional Mendelian randomization study.
Topics: Alzheimer Disease; Betaine; Carnitine; Choline; Female; Gastrointestinal Microbiome; Genetic Predisposition to Disease; Humans; Male; Mendelian Randomization Analysis; Methylamines; Negative Results; Risk | 2021 |
Association of gut-related metabolites with outcome in acute heart failure.
Topics: Acetylcarnitine; Acute Disease; Aged; Aged, 80 and over; Betaine; Carnitine; Choline; Female; Gastrointestinal Microbiome; Heart Failure; Hospital Mortality; Humans; Male; Methylamines; Natriuretic Peptide, Brain; Risk Factors; Statistics, Nonparametric | 2021 |
Gut Microbiota Functional Dysbiosis Relates to Individual Diet in Subclinical Carotid Atherosclerosis.
Topics: Adult; Aged; Aged, 80 and over; Bacteria; Carnitine; Carotid Artery Diseases; Choline; Diet; Dysbiosis; Escherichia coli; Faecalibacterium prausnitzii; Feces; Feeding Behavior; Female; Gastrointestinal Microbiome; High-Throughput Nucleotide Sequencing; Humans; Life Style; Male; Metagenomics; Methylamines; Middle Aged; Palmitates | 2021 |
Using matrix-induced ion suppression combined with LC-MS/MS for quantification of trimethylamine-N-oxide, choline, carnitine and acetylcarnitine in dried blood spot samples.
Topics: Acetylcarnitine; Carnitine; Choline; Chromatography, Liquid; Dried Blood Spot Testing; Humans; Methylamines; Oxides; Reproducibility of Results; Tandem Mass Spectrometry | 2021 |
FMO3-TMAO axis modulates the clinical outcome in chronic heart-failure patients with reduced ejection fraction: evidence from an Asian population.
Topics: Carnitine; Choline; Chronic Disease; Heart Failure; Humans; Methylamines; Oxygenases; Prospective Studies | 2022 |
Simultaneous quantification of trimethylamine N-oxide, trimethylamine, choline, betaine, creatinine, and propionyl-, acetyl-, and L-carnitine in clinical and food samples using HILIC-LC-MS.
Topics: Betaine; Carnitine; Choline; Chromatography, Liquid; Creatinine; Female; Food Analysis; Humans; Limit of Detection; Male; Methylamines; Middle Aged; Tandem Mass Spectrometry | 2021 |
Chlorogenic acid inhibits trimethylamine-
Topics: Animal Feed; Animals; Carnitine; Chlorogenic Acid; Disease Models, Animal; Gastrointestinal Microbiome; Intestines; Liver; Liver Diseases; Male; Methylamines; Mice | 2021 |
The microbial gbu gene cluster links cardiovascular disease risk associated with red meat consumption to microbiota L-carnitine catabolism.
Topics: Animals; Cardiovascular Diseases; Carnitine; Clostridiales; Feces; Female; Gastrointestinal Microbiome; Genes, Bacterial; Germ-Free Life; Humans; Methylamines; Mice; Mice, Inbred C57BL; Multigene Family; Observational Studies as Topic; Red Meat | 2022 |
Gut microbiota-dependent metabolite trimethylamine N-oxide (TMAO) and cardiovascular risk in patients with suspected functionally relevant coronary artery disease (fCAD).
Topics: Betaine; Cardiovascular Diseases; Carnitine; Choline; Coronary Artery Disease; Gastrointestinal Microbiome; Heart Disease Risk Factors; Humans; Methylamines; Risk Factors | 2022 |
Association of Trimethylamine N-Oxide and Metabolites With Mortality in Older Adults.
Topics: Aged; Betaine; Cardiovascular Diseases; Carnitine; Choline; Cohort Studies; Female; Humans; Male; Methylamines; Prospective Studies | 2022 |
The associations between TMAO-related metabolites and blood lipids and the potential impact of rosuvastatin therapy.
Topics: Atherosclerosis; Betaine; Carnitine; Cholesterol, LDL; Choline; Humans; Lipids; Methylamines; Rosuvastatin Calcium; Tandem Mass Spectrometry | 2022 |
Dietary Meat, Trimethylamine N-Oxide-Related Metabolites, and Incident Cardiovascular Disease Among Older Adults: The Cardiovascular Health Study.
Topics: Animals; Atherosclerosis; Cardiovascular Diseases; Carnitine; Humans; Meat; Methylamines; Risk Factors | 2022 |
Longitudinal Associations of Plasma TMAO and Related Metabolites with Cognitive Impairment and Dementia in Older Adults: The Cardiovascular Health Study.
Topics: Animals; Betaine; Carnitine; Choline; Cognitive Dysfunction; Dementia; Medicare; Methylamines; United States | 2022 |
Association of Systemic Trimethyllysine With Heart Failure With Preserved Ejection Fraction and Cardiovascular Events.
Topics: Carnitine; Cross-Sectional Studies; Heart Failure; Humans; Prospective Studies; Stroke Volume | 2022 |
Associations of plasma TMAO and its precursors with stroke risk in the general population: A nested case-control study.
Topics: Betaine; Carnitine; Case-Control Studies; Choline; Humans; Stroke | 2023 |
L-Carnitine Combined with Leucine Supplementation Does Not Improve the Effectiveness of Progressive Resistance Training in Healthy Aged Women.
Topics: Aged; Carnitine; Decorin; Dietary Supplements; Female; Humans; Insulin-Like Growth Factor I; Leucine; Middle Aged; Muscle Strength; Muscle, Skeletal; Myostatin; Resistance Training; Tartrates | 2022 |
TMAO Upregulates Members of the miR-17/92 Cluster and Impacts Targets Associated with Atherosclerosis.
Topics: Animals; Atherosclerosis; Betaine; Cardiovascular Diseases; Carnitine; Choline; Humans; Inflammation; Methylamines; Mice; MicroRNAs | 2022 |
Dietary supplementation of L-carnitine ameliorates metabolic syndrome independent of trimethylamine
Topics: Animals; Carnitine; Diet, High-Fat; Dietary Supplements; Gastrointestinal Microbiome; Humans; Metabolic Syndrome; Methylamines; Mice; Mice, Obese | 2022 |
Beneficial Effects of Essential Oils from the Mediterranean Diet on Gut Microbiota and Their Metabolites in Ischemic Heart Disease and Type-2 Diabetes Mellitus.
Topics: Animals; Carnitine; Diabetes Mellitus, Type 2; Diet, Mediterranean; Emulsions; Fatty Acids, Volatile; Gastrointestinal Microbiome; Mice; Myocardial Ischemia; Oils, Volatile; Prebiotics; Rosmarinus | 2022 |
Quercetin inhibits hepatotoxic effects by reducing trimethylamine-
Topics: Animals; Carnitine; Diet; Methylamines; Mice; Mice, Inbred C57BL; Oxides; Quercetin | 2023 |
TRIMETHYLAMINE OXIDE - FACTOR IN THE DEVELOPMENT OF ATHEROSCLEROSIS AND A POTENTIAL TARGET FOR DIETARY AND PHARMACOLOGICAL INTERVENTIONS.
Topics: Atherosclerosis; Carnitine; Choline; Humans; Methylamines | 2023 |
Trimethylamine N-Oxide and White Matter Hyperintensity Volume Among Patients With Acute Ischemic Stroke.
Topics: Aged; Betaine; Carnitine; Cerebral Small Vessel Diseases; Choline; Cross-Sectional Studies; Female; Humans; Ischemic Stroke; Male; Stroke; Stroke, Lacunar; White Matter | 2023 |