carnitine and trimethyllysine

carnitine has been researched along with trimethyllysine in 62 studies

Research

Studies (62)

Timeframe	Studies, this research(%)	All Research%
pre-1990	32 (51.61)	18.7374
1990's	10 (16.13)	18.2507
2000's	8 (12.90)	29.6817
2010's	8 (12.90)	24.3611
2020's	4 (6.45)	2.80

Authors

Authors	Studies
Nezu, JI; Ohashi, R; Oku, A; Sai, Y; Shimane, M; Tamai, I; Tsuji, A; Yabuuchi, H	1
Carter, AL; Frenkel, R	1
Davis, AT	1
Hoppel, CL; Sandor, A	1
Bosch, EP; Chenard, CA; Nelson, SE; Rebouche, CJ; Schabold, KJ	1
Lehman, LJ; Olson, L; Rebouche, CJ	1
Davis, AT; Hoppel, CL	3
Rebouche, CJ	3
Hörl, WH; Wanner, C	1
Adibi, SA; Gleditsch, CE; Paul, HS	1
Olson, AL; Rebouche, CJ	1
Lehman, LJ; Olson, AL; Rebouche, CJ	1
Bamji, MS; Khan-Siddiqui, L; Murthy, SN; Vijayasarathy, C	1
Franz, HE; Fürst, P; Graser, TA; Kohse, KP	1
Broquist, HP; Tanphaichitr, V	1
Bach, A	1
Dunn, WA; Englard, S; Rettura, G; Seifter, E	1
Broquist, HP; Sachan, DS	1
Engel, AG; Rebouche, CJ	3
Cox, RA; Hoppel, CL; Novak, RF	1
Hoppel, CL; Sachan, DS	1
Henderson, LL; Henderson, LM; Jenness, R; Nelson, PJ; Pruitt, RE	1
Dunn, WA; Englard, S	1
Borum, PR; Broquist, HP	1
Aronson, NN; Dunn, WA; Englard, S	1
Broquist, HP	1
Henderson, L; Henderson, LM; Nelson, PJ	1
Katz, ML; Siakotos, AN	1
Bock, I; Melegh, B; Pap, M; Rebouche, CJ	1
Davis, AT; Kruggel, EM; Randall, S	1
Bock, I; Hermann, R; Melegh, B	1
Katz, ML	1
Adamovich, K; Bieber, LL; Gage, DA; Melegh, B; Szekely, G; Tóth, G	1
Inoue, F; Kinugasa, A; Kizaki, Z; Nakajima, H; Okochi, M; Sawada, T; Terada, N	1
Brass, EP; Hoppel, CL; Krähenbühl, S	1
Bene, J; Bieber, LL; Bootsma, A; Cuebas, D; Gage, DA; Melegh, B; van Gennip, AH; Vaz, FM; Vreken, P; Wanders, RJ	1
Davis, AT; Monroe, TJ	1
van Vlies, N; Vaz, FM; Wanders, RJ	1
Eder, K; Hirche, F; Pösel, S; Ringseis, R	1
Eder, K; Koch, A; König, B; Stangl, GI	1
Eder, K; Fischer, M; Hirche, F; Kluge, H	1
Eder, K; Fischer, M; Hirche, F; Keller, J	1
Eder, K; Hanisch, N; Ringseis, R; Seliger, G	1
Charrier, A; Merlier, F; Perrin, Y; Rippa, S; Zhao, Y	1
Balestrieri, ML; Castaldo, D; Cautela, D; Giovane, A; Servillo, L	1
Abbas, A; Aukrust, P; Berge, RK; Bjerkeli, V; Gregersen, I; Halvorsen, B; Holm, S; Hov, JE; Karlsen, TH; Kummen, M; Reier-Nilsen, F; Russell, D; Skagen, K; Skjelland, M; Svardal, A; Trøseid, M; Ueland, T	1
Leśniak, RK; Markolovic, S; Schofield, CJ; Tars, K	1
Al Temimi, AH; Mecinović, J; Reddy, YV; White, PB	1
Berge, RK; Flygel, MR; Lysne, V; Løland, KH; Nygård, O; Pedersen, ER; Rebnord, EW; Strand, E; Svardal, A; Svingen, GFT; Tell, GS	1
Allayee, H; Buffa, JA; Cajka, T; DiDonato, JA; Fiehn, O; Gu, X; Han, Y; Hartiala, JA; Hazen, SL; Hurd, AG; Kerby, RL; Li, L; Li, XS; Lüscher, TF; Nemet, I; Obeid, S; Rey, FE; Roberts, AB; Romano, KA; Shahen, CJ; Skye, SM; Tang, WHW; Wagner, MA; Wang, Z; Wu, Y	1
Hintzen, JCJ; Maas, MN; Mecinović, J; Porzberg, MRB	1
Gu, S; Liu, D; Ma, Z; Wang, J; Xiao, L; Zhou, Z; Zuo, H	1
Dong, E; Gao, J; Huang, M; Ji, L; Li, C; Wang, DW; Wang, Y; Wei, H; Wu, J; Zhang, Q; Zhao, C; Zhao, M; Zheng, L	1
Abe, T; Bhuiya, J; Isomura, M; Kobayashi, H; Nabika, T; Nagai, A; Notsu, Y; Okazaki, R; Sheikh, AM; Shibly, AZ; Yamaguchi, K; Yamasaki, M; Yano, S	1

Reviews

3 review(s) available for carnitine and trimethyllysine

Article	Year
Carnitine biosynthesis in rat and man: tissue specificity. Nutrition reviews, 1981, Volume: 39, Issue:1 Topics: Aldehydes; Animals; Betaine; Carnitine; Humans; Hydroxylysine; Lysine; Organ Specificity; Rats; Species Specificity	1981
Carnitine biosynthesis: nutritional implications. Advances in nutritional research, 1982, Volume: 4 Topics: Adenosine Triphosphate; Adolescent; Adult; Aged; Animals; Carnitine; Child; Child, Preschool; Female; Food Analysis; Humans; Infant; Infant, Newborn; Kidney Diseases; Liver Cirrhosis; Lysine; Methionine; Middle Aged; Milk, Human; Mitogens; Muscles; Muscular Diseases; Pregnancy; Protein Deficiency; Rats	1982
Trimethyllysine: From Carnitine Biosynthesis to Epigenetics. International journal of molecular sciences, 2020, Dec-11, Volume: 21, Issue:24 Topics: Animals; Carnitine; Epigenesis, Genetic; Histone-Lysine N-Methyltransferase; Humans; Lysine; Protein Processing, Post-Translational	2020

Other Studies

59 other study(ies) available for carnitine and trimethyllysine

Article	Year
Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): its pharmacological and toxicological relevance. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:2 Topics: Biological Transport, Active; Carnitine; Carrier Proteins; Cations; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Humans; Hydrogen-Ion Concentration; Kidney; Membrane Proteins; Organic Cation Transport Proteins; Sodium; Solute Carrier Family 22 Member 5; Stereoisomerism	1999
The role of the kidney in the biosynthesis of carnitine in the rat. The Journal of biological chemistry, 1979, Nov-10, Volume: 254, Issue:21 Topics: Animals; Carnitine; Isotope Labeling; Kidney; Kinetics; Liver; Lysine; Nephrectomy; Organ Specificity; Rats; Tritium	1979
Tissue trimethyllysine biosynthesis and carnitine content in pregnant and lactating rats fed a lysine-limiting diet. The Journal of nutrition, 1990, Volume: 120, Issue:8 Topics: Animals; Animals, Newborn; Carnitine; Diet; Female; Kinetics; Lactation; Liver; Lysine; Male; Maternal-Fetal Exchange; Milk; Muscles; Myocardium; Pregnancy; Pregnancy, Animal; Rats; Rats, Inbred Strains; Saccharopine Dehydrogenases; Tissue Distribution	1990
Butyrobetaine availability in liver is a regulatory factor for carnitine biosynthesis in rat. Flux through butyrobetaine hydroxylase in fasting state. European journal of biochemistry, 1989, Nov-20, Volume: 185, Issue:3 Topics: Animals; Betaine; Biological Availability; Carnitine; Fasting; gamma-Butyrobetaine Dioxygenase; Liver; Lysine; Male; Mixed Function Oxygenases; Rats; Rats, Inbred Strains; Whole-Body Counting	1989
Utilization of dietary precursors for carnitine synthesis in human adults. The Journal of nutrition, 1989, Volume: 119, Issue:12 Topics: Adult; Betaine; Carnitine; Diet, Vegetarian; Dietary Proteins; Female; Humans; Lysine; Male; Methionine; Muscles; Nutritional Requirements; Protein Precursors	1989
epsilon-N-trimethyllysine availability regulates the rate of carnitine biosynthesis in the growing rat. The Journal of nutrition, 1986, Volume: 116, Issue:5 Topics: Administration, Oral; Animals; Biological Availability; Body Weight; Carnitine; Injections, Intravenous; Lysine; Male; Mixed Function Oxygenases; Organ Size; Rats; Rats, Inbred Strains; Tissue Distribution; Tritium	1986
Effect of starvation on the disposition of free and peptide-linked trimethyllysine in the rat. The Journal of nutrition, 1986, Volume: 116, Issue:5 Topics: Animals; Carnitine; Kidney; Liver; Lysine; Male; Muscles; Rats; Rats, Inbred Strains; Starvation	1986
Synthesis of carnitine precursors and related compounds. Methods in enzymology, 1986, Volume: 123 Topics: Amines; Animals; Betaine; Carnitine; Hydroxylysine; Lysine; Rats	1986
Inter-tissue relationships in the synthesis and distribution of carnitine. Biochemical Society transactions, 1986, Volume: 14, Issue:4 Topics: Animals; Carnitine; Glycine Hydroxymethyltransferase; Histone-Lysine N-Methyltransferase; Kidney; Liver; Lysine; Rats; Tissue Distribution	1986
Potential role of carnitine in patients with renal insufficiency. Klinische Wochenschrift, 1986, Jul-01, Volume: 64, Issue:13 Topics: Acetylcarnitine; Carnitine; Carnitine O-Palmitoyltransferase; Creatinine; Humans; Hyperlipidemias; Kidney Failure, Chronic; Kidney Transplantation; Kidney Tubules, Proximal; Lysine; Muscles; Peritoneal Dialysis; Peritoneal Dialysis, Continuous Ambulatory; Renal Dialysis; Rhabdomyolysis; Uremia	1986
Mechanism of increased hepatic concentration of carnitine by clofibrate. The American journal of physiology, 1986, Volume: 251, Issue:3 Pt 1 Topics: Animals; Carnitine; Clofibrate; Esterification; Liver; Lysine; Male; Rats; Rats, Inbred Strains; Thyroidectomy	1986
gamma-Butyrobetaine hydroxylase activity is not rate limiting for carnitine biosynthesis in the human infant. The Journal of nutrition, 1987, Volume: 117, Issue:6 Topics: Adolescent; Adult; Aged; Aging; Betaine; Carnitine; Child, Preschool; Female; gamma-Butyrobetaine Dioxygenase; Humans; Infant; Infant, Newborn; Kidney; Liver; Lysine; Male; Middle Aged; Mixed Function Oxygenases	1987
Measurement of epsilon-N-trimethyllysine in human blood plasma and urine. Analytical biochemistry, 1987, Volume: 162, Issue:1 Topics: Amino Acids; Carnitine; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Humans; Lysine; Spectrometry, Fluorescence	1987
Rise in plasma trimethyllysine levels in humans after oral lysine load. The American journal of clinical nutrition, 1987, Volume: 46, Issue:5 Topics: Administration, Oral; Adult; Carnitine; Humans; Lysine; Male; Time Factors; Tryptophan	1987
Plasma levels of carnitine precursor 6-N-trimethyllysine and maintenance hemodialysis. Kidney international. Supplement, 1987, Volume: 22 Topics: Adolescent; Adult; Carnitine; Chromatography, High Pressure Liquid; Female; Humans; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Renal Dialysis	1987
The Journal of Biological Chemistry. Volume 248, 1973: Role of lysine and epsilon-n-trimethyllysine in carnitine biosynthesis. II. Studies in the rat. By Vichai Tanphaichitr and Harry P. Broquist. Nutrition reviews, 1988, Volume: 46, Issue:4 Topics: Animals; Carnitine; History, 20th Century; Lysine; Male; Rats	1988
Carnitine synthesis in scorbutic guinea pigs. Nutrition reviews, 1985, Volume: 43, Issue:6 Topics: Animals; Carnitine; gamma-Aminobutyric Acid; Guinea Pigs; Hydroxylation; Lysine; Male; Scurvy; Tissue Distribution	1985
[Carnitine biosynthesis in mammals]. Reproduction, nutrition, developpement, 1982, Volume: 22, Issue:4 Topics: Age Factors; Animals; Betaine; Carnitine; Humans; Lysine; Mammals; Methionine; Neurospora crassa; Tissue Distribution	1982
Effect of starvation in the rat on trimethyllysine in peptide linkage. The Journal of nutrition, 1983, Volume: 113, Issue:5 Topics: Animals; Body Weight; Brain; Carnitine; Lysine; Male; Muscles; Peptides; Rats; Rats, Inbred Strains; Starvation; Tissue Distribution	1983
Carnitine biosynthesis from gamma-butyrobetaine and from exogenous protein-bound 6-N-trimethyl-L-lysine by the perfused guinea pig liver. Effect of ascorbate deficiency on the in situ activity of gamma-butyrobetaine hydroxylase. The Journal of biological chemistry, 1984, Sep-10, Volume: 259, Issue:17 Topics: Animals; Ascorbic Acid Deficiency; Betaine; Carbon Radioisotopes; Carnitine; gamma-Butyrobetaine Dioxygenase; Guinea Pigs; Liver; Lysine; Male; Methylation; Mixed Function Oxygenases; Orosomucoid; Perfusion; Tissue Distribution; Tritium	1984
Synthesis of carnitine from epsilon-N-trimethyllysine in post mitochondrial fractions of Neurospora crassa. Biochemical and biophysical research communications, 1980, Sep-30, Volume: 96, Issue:2 Topics: Betaine; Carnitine; Cell-Free System; Cytosol; Lysine; Mitochondria; Neurospora; Neurospora crassa; Subcellular Fractions	1980
Tissue distribution of carnitine biosynthetic enzymes in man. Biochimica et biophysica acta, 1980, Jun-05, Volume: 630, Issue:1 Topics: Adolescent; Adult; Aging; Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; Aldehyde-Lyases; Carnitine; Child; Child, Preschool; Female; gamma-Butyrobetaine Dioxygenase; Glucuronates; Humans; Infant; Kinetics; Lactones; Lysine; Male; Middle Aged; Mixed Function Oxygenases; Organ Specificity; Tissue Distribution	1980
N6-Trimethyl-lysine metabolism. 3-Hydroxy-N6-trimethyl-lysine and carnitine biosynthesis. The Biochemical journal, 1980, May-15, Volume: 188, Issue:2 Topics: Animals; Carbon Radioisotopes; Carnitine; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Hydroxylysine; Kidney; Liver; Lysine; Models, Biological; Rats; Tritium	1980
Carnitine biosynthesis. Hydroxylation of N6-trimethyl-lysine to 3-hydroxy-N6-trimethyl-lysine. The Biochemical journal, 1980, May-15, Volume: 188, Issue:2 Topics: Animals; Calcium; Carnitine; Cations, Divalent; Edetic Acid; Hydroxylation; In Vitro Techniques; Kidney; Kinetics; Lysine; Male; Mixed Function Oxygenases; Proteins; Rats; Subcellular Fractions	1980
Significance of renal gamma-butyrobetaine hydroxylase for carnitine biosynthesis in man. The Journal of biological chemistry, 1980, Sep-25, Volume: 255, Issue:18 Topics: Adult; Animals; Brain; Carnitine; gamma-Butyrobetaine Dioxygenase; Humans; Kidney; Liver; Lysine; Male; Mixed Function Oxygenases; Muscles; Myocardium; Organ Specificity; Rats; Species Specificity	1980
Effect of ascorbic acid deficiency on the in vivo synthesis of carnitine. Biochimica et biophysica acta, 1981, Jan-07, Volume: 672, Issue:1 Topics: Animals; Ascorbic Acid Deficiency; Body Weight; Carnitine; gamma-Aminobutyric Acid; Guinea Pigs; Kidney; Liver; Lysine; Male; Muscles; Myocardium; Organ Size	1981
Primary systemic carnitine deficiency: I. Carnitine biosynthesis. Neurology, 1981, Volume: 31, Issue:7 Topics: Adult; Carnitine; Child; Chromatography, Ion Exchange; Female; Humans; Lysine; Male	1981
Carnitine biosynthesis by the perfused rat liver from exogenous protein-bound trimethyllysine. Metabolism of methylated lysine derivatives arising from the degradation of 6-N-[methyl-3H]lysine-labeled glycoproteins. The Journal of biological chemistry, 1981, Dec-10, Volume: 256, Issue:23 Topics: Animals; Carnitine; Glycoproteins; Kinetics; Liver; Lysine; Male; Mitogens; Perfusion; Rats; Rats, Inbred Strains	1981
The effects of 1-amino-D-proline on the production of carnitine from exogenous protein-bound trimethyllysine by the perfused rat liver. The Journal of biological chemistry, 1982, Jul-25, Volume: 257, Issue:14 Topics: Animals; Carnitine; In Vitro Techniques; Kinetics; Liver; Lysine; Male; Mitogens; Perfusion; Proline; Rats; Rats, Inbred Strains	1982
Carnitine biosynthesis and function. Introductory remarks. Federation proceedings, 1982, Volume: 41, Issue:12 Topics: Animals; Carnitine; Carnitine Acyltransferases; Cattle; Chemical Phenomena; Chemistry; Cytoplasm; Fatty Acids; Humans; Intracellular Membranes; Liver; Lysine; Mitochondria; Rats	1982
Mammalian enzymes of trimethyllysine conversion to trimethylaminobutyrate. Federation proceedings, 1982, Volume: 41, Issue:12 Topics: Aldehyde Oxidoreductases; Animals; Carnitine; Cattle; Chemical Phenomena; Chemistry; gamma-Aminobutyric Acid; Glycine Hydroxymethyltransferase; Guinea Pigs; Kidney; Kinetics; Liver; Lysine; Mitochondria, Liver; Mixed Function Oxygenases; Rats	1982
Sites and regulation of carnitine biosynthesis in mammals. Federation proceedings, 1982, Volume: 41, Issue:12 Topics: Adult; Animals; Animals, Suckling; Brain; Carnitine; Cats; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Cricetinae; Dogs; gamma-Butyrobetaine Dioxygenase; Guinea Pigs; Haplorhini; Humans; Kidney; Liver; Lysine; Male; Mice; Mixed Function Oxygenases; Rabbits; Rats	1982
Canine hereditary ceroid-lipofuscinosis: evidence for a defect in the carnitine biosynthetic pathway. American journal of medical genetics, 1995, Jun-05, Volume: 57, Issue:2 Topics: Animals; Biomarkers; Carnitine; Dog Diseases; Dogs; Genetic Carrier Screening; Homozygote; Humans; Lysine; Macromolecular Substances; Mammals; Mitochondria; Neuronal Ceroid-Lipofuscinoses; Proton-Translocating ATPases; Reference Values	1995
The ability of guinea pigs to synthesize carnitine at a normal rate from epsilon-N-trimethyllysine or gamma-butyrobetaine in vivo is not compromised by experimental vitamin C deficiency. Metabolism: clinical and experimental, 1995, Volume: 44, Issue:5 Topics: Analysis of Variance; Animals; Ascorbic Acid Deficiency; Betaine; Carnitine; Food, Fortified; Guinea Pigs; Lysine; Male; Reference Values; Time Factors; Weight Gain	1995
Relationship of carnitine and carnitine precursors lysine, epsilon-N-trimethyllysine, and gamma-butyrobetaine in drug-induced carnitine depletion. Pediatric research, 1993, Volume: 34, Issue:4 Topics: Adolescent; Bacteriuria; Betaine; Carnitine; Child; Child, Preschool; Creatinine; Epilepsy; Female; Humans; Lysine; Male; Pivampicillin; Urinary Tract Infections; Valproic Acid	1993
Excess dietary lysine increases skeletal muscle and plasma trimethyllysine in rats. The Journal of nutrition, 1993, Volume: 123, Issue:6 Topics: Animals; Carnitine; Diet; Heart; Liver; Lysine; Male; Muscles; Myocardium; Proline; Rats; Rats, Sprague-Dawley	1993
Generation of hydroxytrimethyllysine from trimethyllysine limits the carnitine biosynthesis in premature infants. Acta paediatrica (Oslo, Norway : 1992), 1996, Volume: 85, Issue:3 Topics: Carnitine; Humans; Infant, Newborn; Infant, Premature; Lysine; Male; Spectrometry, Mass, Fast Atom Bombardment	1996
Decreased plasma carnitine and trimethyl-L-lysine levels associated with lysosomal accumulation of a trimethyl-L-lysine containing protein in Batten disease. Biochimica et biophysica acta, 1996, Dec-16, Volume: 1317, Issue:3 Topics: Adult; Carnitine; Child; Female; Heterozygote; Humans; Lysine; Male; Neuronal Ceroid-Lipofuscinoses	1996
Labeled trimethyllysine load depletes unlabeled carnitine in premature infants without evidence of incorporation. Biology of the neonate, 1999, Volume: 76, Issue:1 Topics: Carnitine; Dose-Response Relationship, Drug; Humans; Infant, Newborn; Infant, Premature; Lysine; Male; Protein Precursors; Spectrometry, Mass, Fast Atom Bombardment; Time Factors	1999
Measurement of carnitine precursors, epsilon-trimethyllysine and gamma-butyrobetaine in human serum by tandem mass spectrometry. Journal of chromatography. B, Biomedical sciences and applications, 1999, Aug-06, Volume: 731, Issue:1 Topics: Betaine; Carnitine; Humans; Lysine; Mass Spectrometry; Methylation; Reference Standards; Sensitivity and Specificity	1999
Decreased carnitine biosynthesis in rats with secondary biliary cirrhosis. Hepatology (Baltimore, Md.), 2000, Volume: 31, Issue:6 Topics: Animals; Betaine; Bile Ducts; Carnitine; Ligation; Liver Cirrhosis, Biliary; Lysine; Male; Rats; Rats, Sprague-Dawley; Reference Values	2000
Analysis of carnitine biosynthesis metabolites in urine by HPLC-electrospray tandem mass spectrometry. Clinical chemistry, 2002, Volume: 48, Issue:6 Pt 1 Topics: Carnitine; Chromatography, High Pressure Liquid; Deuterium; Humans; Infant, Newborn; Lysine; Male; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization	2002
Carnitine deficiency and supplementation do not affect the gene expression of carnitine biosynthetic enzymes in rats. The Journal of nutrition, 2005, Volume: 135, Issue:4 Topics: Animals; Carnitine; Dietary Supplements; gamma-Butyrobetaine Dioxygenase; Gene Expression Regulation; Kidney; Liver; Lysine; Male; Mixed Function Oxygenases; Pentanoic Acids; Rats; RNA, Messenger	2005
Measurement of carnitine biosynthesis enzyme activities by tandem mass spectrometry: differences between the mouse and the rat. Analytical biochemistry, 2006, Jul-01, Volume: 354, Issue:1 Topics: Aldehyde Dehydrogenase; Aldehydes; Animals; Carnitine; Dioxygenases; gamma-Butyrobetaine Dioxygenase; Kinetics; Liver; Lysine; Male; Mass Spectrometry; Mice; Oxidoreductases; Rats; Species Specificity; Tissue Distribution	2006
Treatment with pharmacological peroxisome proliferator-activated receptor alpha agonist clofibrate causes upregulation of organic cation transporter 2 in liver and small intestine of rats. Pharmacological research, 2007, Volume: 56, Issue:2 Topics: Acyl-CoA Oxidase; Aldehyde-Lyases; Animals; Betaine; Carnitine; Carnitine O-Palmitoyltransferase; Clofibrate; Cytochrome P-450 CYP4A; gamma-Butyrobetaine Dioxygenase; Hypolipidemic Agents; Intestine, Small; Liver; Lysine; Male; Muscle, Skeletal; Organic Cation Transport Proteins; PPAR alpha; Rats; Rats, Sprague-Dawley; RNA, Messenger; Solute Carrier Family 22 Member 5; Up-Regulation	2007
PPAR alpha mediates transcriptional upregulation of novel organic cation transporters-2 and -3 and enzymes involved in hepatic carnitine synthesis. Experimental biology and medicine (Maywood, N.J.), 2008, Volume: 233, Issue:3 Topics: Animals; Betaine; Body Weight; Carnitine; Liver; Lysine; Male; Membrane Proteins; Mice; Mice, Knockout; Organ Size; Organ Specificity; Organic Cation Transport Proteins; PPAR alpha; RNA, Messenger; Solute Carrier Family 22 Member 5; Transcription, Genetic; Up-Regulation	2008
A moderate excess of dietary lysine lowers plasma and tissue carnitine concentrations in pigs. The British journal of nutrition, 2009, Volume: 101, Issue:2 Topics: Animal Feed; Animals; Betaine; Carnitine; gamma-Butyrobetaine Dioxygenase; Gene Expression; Kidney; Liver; Lysine; Male; Mixed Function Oxygenases; Muscles; Nutritional Status; Organic Cation Transport Proteins; Reverse Transcriptase Polymerase Chain Reaction; Swine	2009
Determination of carnitine, its short chain acyl esters and metabolic precursors trimethyllysine and gamma-butyrobetaine by quasi-solid phase extraction and MS/MS detection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2009, Jul-15, Volume: 877, Issue:22 Topics: Animals; Betaine; Carnitine; Esters; Humans; Lysine; Male; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Swine; Tandem Mass Spectrometry	2009
Low availability of carnitine precursors as a possible reason for the diminished plasma carnitine concentrations in pregnant women. BMC pregnancy and childbirth, 2010, Apr-25, Volume: 10 Topics: Adult; Anemia, Iron-Deficiency; Betaine; Carnitine; Erythrocyte Indices; Female; Ferritins; Germany; Hemoglobins; Humans; Linear Models; Lysine; Pregnancy; Pregnancy Complications, Hematologic; Pregnancy Trimester, Third	2010
The carnitine biosynthetic pathway in Arabidopsis thaliana shares similar features with the pathway of mammals and fungi. Plant physiology and biochemistry : PPB, 2012, Volume: 60 Topics: Animals; Arabidopsis; Betaine; Biosynthetic Pathways; Carnitine; Chromatography, Liquid; Deuterium; Fungi; Lipid Metabolism; Lysine; Mammals; Plant Extracts; Seedlings; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Vitamin B Complex	2012
Where does N(ε)-trimethyllysine for the carnitine biosynthesis in mammals come from? PloS one, 2014, Volume: 9, Issue:1 Topics: Animals; Biosynthetic Pathways; Carnitine; Chromatography, Liquid; Chromatography, Reverse-Phase; Fluorescence; Lysine; Mammals; Plant Extracts; Spectrometry, Mass, Electrospray Ionization; Vegetables	2014
The Carnitine-butyrobetaine-trimethylamine-N-oxide pathway and its association with cardiovascular mortality in patients with carotid atherosclerosis. Atherosclerosis, 2016, Volume: 247 Topics: Aged; Betaine; Biomarkers; Carnitine; Carotid Stenosis; Case-Control Studies; Cause of Death; Chromatography, High Pressure Liquid; Female; Humans; Kaplan-Meier Estimate; Lysine; Male; Methylamines; Middle Aged; Myocardial Infarction; Prognosis; Proportional Hazards Models; Risk Assessment; Risk Factors; Severity of Illness Index; Stroke; Ultrasonography, Doppler, Color	2016
Human carnitine biosynthesis proceeds via (2S,3S)-3-hydroxy-N Chemical communications (Cambridge, England), 2016, 12-22, Volume: 53, Issue:2 Topics: Biocatalysis; Carnitine; Humans; Lysine; Mixed Function Oxygenases; Models, Molecular; Protein Conformation; Stereoisomerism; Substrate Specificity	2016
Evidence That Trimethyllysine Hydroxylase Catalyzes the Formation of (2S,3S)-3-Hydroxy-N Organic letters, 2017, 01-20, Volume: 19, Issue:2 Topics: Biocatalysis; Carnitine; Humans; Lysine; Mixed Function Oxygenases; Molecular Structure	2017
Serum Carnitine Metabolites and Incident Type 2 Diabetes Mellitus in Patients With Suspected Stable Angina Pectoris. The Journal of clinical endocrinology and metabolism, 2018, 03-01, Volume: 103, Issue:3 Topics: Aged; Angina, Stable; Betaine; Body Mass Index; Carnitine; Chromatography, Liquid; Coronary Artery Disease; Diabetes Mellitus, Type 2; Esters; Female; Humans; Logistic Models; Lysine; Male; Middle Aged; Odds Ratio; Prospective Studies; Risk Factors	2018
Untargeted metabolomics identifies trimethyllysine, a TMAO-producing nutrient precursor, as a predictor of incident cardiovascular disease risk. JCI insight, 2018, 03-22, Volume: 3, Issue:6 Topics: Aged; Animals; Atherosclerosis; Cardiovascular Diseases; Carnitine; Cholesterol; Choline; Disease Models, Animal; Feces; Female; Gastrointestinal Microbiome; Genome-Wide Association Study; Humans; Lysine; Male; Metabolomics; Methylamines; Mice; Mice, Inbred C57BL; Middle Aged; Nutrients; Risk Factors; Thrombosis	2018
Associations of plasma carnitine, lysine, trimethyllysine and glycine with incident ischemic stroke: Findings from a nested case-control study. Clinical nutrition (Edinburgh, Scotland), 2022, Volume: 41, Issue:9 Topics: Carnitine; Case-Control Studies; Fabaceae; Glycine; Humans; Ischemic Stroke; Lysine; Stroke; Tandem Mass Spectrometry	2022
Association of Systemic Trimethyllysine With Heart Failure With Preserved Ejection Fraction and Cardiovascular Events. The Journal of clinical endocrinology and metabolism, 2022, 11-25, Volume: 107, Issue:12 Topics: Carnitine; Cross-Sectional Studies; Heart Failure; Humans; Prospective Studies; Stroke Volume	2022
Neither Trimethylamine-N-Oxide nor Trimethyllysine Is Associated with Atherosclerosis: A Cross-Sectional Study in Older Japanese Adults. Nutrients, 2023, Feb-02, Volume: 15, Issue:3 Topics: Animals; Atherosclerosis; Carnitine; Carotid Intima-Media Thickness; Choline; Cross-Sectional Studies; East Asian People; Female; Humans; Methylamines; Oxides	2023