carnitine has been researched along with propionylcarnitine in 330 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 32 (9.70) | 18.7374 |
| 1990's | 157 (47.58) | 18.2507 |
| 2000's | 82 (24.85) | 29.6817 |
| 2010's | 53 (16.06) | 24.3611 |
| 2020's | 6 (1.82) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, J; Conway, SJ; Ganapathy, V; Huang, W; Leibach, FH; Prasad, PD; Rajan, DP; Seth, P; Wu, X | 1 |
| Bertelli, A; Bertelli, AA; Giovannini, L | 2 |
| De Martini, D; De Rossi, S; Gerardino, L; Pola, P; Tondi, P | 1 |
| Comini, L; de Giuli, F; Dhalla, NS; Ferrari, R; Menotti, A; Pasini, E | 1 |
| Bertelli, A; Ronca, F; Ronca, G; Yu, G; Zucchi, R | 1 |
| Kagan, VE; Khwaja, S; Packer, L; Ramsey, R; Reznick, AZ; Serbinova, EA; Tsuchiya, M | 1 |
| Bartels, GL; Cox, PH; Knufman, NM; Kruijssen, HA; Pillay, M; Remme, WJ; Schönfeld, DH | 1 |
| Benatti, P; Bianchi, G; Cardace, G; English, E; Micheletti, R; Motterlini, R; Samaja, M; Tarantola, M; Yang, XP | 1 |
| Bertelli, A; Ronca-Testoni, S; Spaggiari, PG; Zucchi, R | 1 |
| Lingetti, M; Mancini, M; Nolfe, G; Rengo, F; Sorrentino, GP | 1 |
| Paulson, DJ; Shug, AL; Zhao, J | 1 |
| Bianchi, G; Micheletti, R; Motterlini, R; Samaja, M; Tarantola, M | 1 |
| Bezstarosti, K; Duncker, DJ; Hogendoorn, A; Krams, R; Lamers, JM; McFalls, EO; Sassen, LM; Verdouw, PD | 1 |
| Latte, S; Lizzadro, A; Mastursi, M; Nolfe, G; Pucciarelli, G; Sacra, C; Setaro, A | 1 |
| Sakuma, T; Sugiyama, N; Wada, Y | 1 |
| Berardi, E; Brevetti, G; Godi, L; Perna, S; Rossini, A; Sabbà, C; Scotto di Uccio, V | 1 |
| Coto, V; D'Alessandro, L; Grattarola, G; Imparato, L; Lingetti, M; Mancini, M; Nolfe, G; Rengo, F | 1 |
| Barbato, R; Barbieri, M; Ceconi, C; Cerbai, E; de Jong, JW; Di Lisa, F; Ferrari, R; Menabò, R; Mugelli, A; Pasini, E | 1 |
| Cargnoni, A; Condorelli, E; Ferrari, R; Lisciani, R; Marzo, A; Pasini, E | 1 |
| Bianchi, M; Ghirlanda, G; Greco, AV; Mingrone, G | 1 |
| Frost, K; Kagan, V; Packer, L; Serbinova, E; Starke-Reed, P; Valenza, M | 1 |
| Lagioia, R; Mangini, SG; Mastropasqua, F; Ramunni, G; Ricci, A; Rizzon, P; Scrutinio, D; Totaro Fila, G; Valentini, G | 1 |
| Flore, R; Pola, P; Serricchio, M; Tondi, P | 1 |
| Bhatnagar, R; Leipälä, JA; Massoumi, K; Najibi, S; Packer, L; Pineda, E | 1 |
| Bolukoglu, H; Eggleston, AM; Liedtke, AJ; Nellis, SH; Subramanian, R | 1 |
| Arrigoni Martelli, E; Bassani, E; Cardace, G; Corbelleta, C; Marzo, A; Morabito, E | 1 |
| Arrigoni Martelli, E; Bassani, E; Cardace, G; Corbelletta, C; Mancinelli, A; Marzo, A; Solbiati, M | 1 |
| Dhalla, NS; Ferrari, R; Kolár, F; Shah, KR | 1 |
| Bevilacqua, M; Norbiato, G; Vago, T | 1 |
| Bezstarosti, K; Lamers, JM; Sassen, LM; Van der Giessen, WJ; Verdouw, PD | 1 |
| Sakuma, T | 1 |
| Bertelli, A; Conte, A; Ronca, G; Zucchi, R | 1 |
| Carbonin, PU; Di Gennaro, M; Gambassi, G; Lo Giudice, P; Pacifici, L; Pahor, M; Ramacci, MT; Sgadari, A | 1 |
| Bertelli, A; Conte, A; Palmieri, L; Ronca, G; Segnini, D; Yu, G | 1 |
| Bertelli, A; Conte, A; Ronca, G; Segnini, D; Yu, G | 1 |
| Angelini, C; Brevetti, G; Carrozzo, R; Corsi, M; Marcialis, A; Matarazzo, A; Perna, S; Rosa, M | 1 |
| Flore, R; Nolfe, G; Pola, P; Tondi, P | 1 |
| Brass, EP; Gandour, RD; Griffith, OW | 1 |
| Chiddo, A; Gaglione, A; Grimaldi, N; Locuratolo, N; Musci, S; Rizzon, P; Troito, G | 1 |
| Di Lisa, F; Menabò, R; Siliprandi, N | 1 |
| Boraso, A; Condorelli, E; Ferrari, R; Lisciani, R; Marzo, A; Pasini, E; Visiou, O | 1 |
| Cerutti, G; Cevese, A; Schena, F | 1 |
| Boffa, GM; Cargnoni, A; Ceconi, C; Curello, S; Ferrari, R; Pasini, E; Visioli, O | 1 |
| Corr, PB; Dobmeyer, DJ; Kanter, EM; Priori, SG; Yamada, KA | 1 |
| Hülsmann, WC | 1 |
| Paulson, D; Regitz, V; Shug, A; Subramanian, R | 1 |
| Kordenat, K; Leasure, JE | 1 |
| Scheffer, MA; van Hinsbergh, VW | 1 |
| Barbieri, M; Carbonin, PU; Cerbai, E; Gambassi, G; Lo Giudice, P; Masini, I; Mugelli, A; Pahor, M | 1 |
| Di Biase, M; Favale, S; Pitzalis, MV; Rizzon, P; Tritto, M | 1 |
| Arrigoni Martelli, E; Cardace, G; Esposito, G; Lindi, C; Marciani, P; Marzo, A | 1 |
| Bertelli, A; Giovannini, L; Mian, M; Spaggiari, PG | 1 |
| Bezstarosti, K; Koning, MM; Lamers, JM; Sassen, LM; van der Giessen, WJ; Verdouw, PD | 1 |
| Dhalla, NS; Ferrari, R; Pierce, GN; Ramjiawan, B | 1 |
| Bonta, IL; Elliott, GR; Lauwen, AP | 1 |
| Corbucci, GG; D'Iddio, S; Mancinelli, G; Montanari, G | 1 |
| Arduini, A; Belfiglio, M; Di Toppi, GS; Federici, G; Fernandez, E; Mancinelli, G; Pallini, R; Scurti, R | 1 |
| Cherchi, A; Corsi, M; Lai, C; Onnis, E; Orani, E; Pirisi, R; Pisano, MR; Soro, A | 1 |
| Kidouchi, K; Kobayashi, M; Sugiyama, N; Wada, Y | 1 |
| Aomine, M; Arita, M; Nobe, S | 1 |
| Caiati, C; Chiddo, A; Galantino, A; Ricci, A; Rizzon, P; Scrutinio, D; Valentini, G | 1 |
| Brass, EP; Ruff, LJ | 1 |
| Beckeringh, TE; Duran, M; Ketting, D; Leupold, D; Wadman, SK | 1 |
| Beyerinck, RA; Brass, EP | 1 |
| Bieber, LL; Jakobs, C; Penn, D; Schmidt-Sommerfeld, E | 1 |
| Jeffrey, FM; Malloy, CR; Rajagopal, A; Roby, RE; Sherry, AD | 1 |
| Brass, EP; Stabler, SP | 1 |
| Arrigoni Martelli, E; Marzo, A; Monti, N; Ripamonti, M | 1 |
| Bertelli, A; Rossini, D; Schinetti, ML | 1 |
| Aomine, M; Arita, M; Shimada, T | 1 |
| Di Lisa, F; Miotto, G; Pivetta, A; Siliprandi, D; Siliprandi, N | 1 |
| Liedkte, AJ; Molaparast-Saless, F; Nellis, SH | 1 |
| Bandinelli, M; Neri, B; Neri, GC | 1 |
| DeMaison, L; Liedtke, AJ; Nellis, SH | 1 |
| Aomine, M; Arita, M | 1 |
| Kidouchi, K; Morishita, H; Nagai, S; Sakakibara, J; Sugiyama, N; Wada, Y | 1 |
| Cooper, TG; Gudermann, TW; Yeung, CH | 1 |
| Bremer, J; Hokland, BM | 1 |
| Noonan, J; Paulson, DJ; Schmidt, M; Shug, AL; Traxler, J | 1 |
| Brass, EP; Fennessey, PV; Miller, LV | 1 |
| Okuyama, M; Yamaguchi, S; Yamamoto, H | 1 |
| Kamiya, K; Kawase, A; Morishita, H; Nagaya, S; Nakajima, T; Ohya, A; Sugiyama, N; Sugiyama, S; Togari, H; Watanabe, I | 1 |
| Chalmers, RA; Hoppel, CL; Roe, CR; Stacey, TE | 1 |
| Liberato, DJ; Millington, DS; Yergey, AL | 1 |
| Böhles, H; Lehnert, W | 1 |
| Chalmers, RA; Hoppel, CL; Millington, DS; Roe, CR; Stacey, TE; Tracey, BM | 1 |
| Di Donato, S; Garavaglia, B; Rimoldi, M; Uziel, G | 1 |
| Bohan, TP; Hoppel, CL; Maltby, DA; Millington, DS; Roe, CR | 1 |
| Bremer, J; Davis, EJ; Spydevold, O | 1 |
| Kotaka, K; Miyazaki, Y; Ogawa, K; Ozawa, T; Satake, T; Sugiyama, S | 1 |
| Kato, T; Kotaka, K; Miyazaki, Y; Ozawa, T; Sugiyama, S; Suzuki, S | 1 |
| Bertelli, A; Bianchi, I; Conte, A; Guazzelli, M; Ronca, G; Taponeco, G | 1 |
| Bartels, GL; Bezstarosti, K; Duncker, DJ; Krams, R; Lamers, JM; McFalls, EO; Sassen, LM; van Meegen, JR; Verdouw, PD | 1 |
| Allard, MF; Lopaschuk, GD; Schönekess, BO | 2 |
| Brevetti, G; Condorelli, M; Martone, VD; Perna, S; Sabbá, C | 1 |
| De Angelis, C; Marino, B; Mauriello, A; Orlandi, A; Ramacci, MT; Spagnoli, LG | 1 |
| Cerutti, G; Cevese, A; Poltronieri, R; Schena, F | 1 |
| Boerrigter, ME; Odiet, JA; Wei, JY | 1 |
| Corsi, C; D'Iddio, S; Giordano, S; Leanza, D; Marrapodi, E; Pollastri, M | 1 |
| Cameron, NE; Cotter, MA; Dines, KC; Keegan, A | 1 |
| Broderick, TL; DiDomenico, D; Paulson, DJ; Shug, AL | 1 |
| Anversa, P; Bianchi, G; Cheng, W; Li, B; Li, P; Micheletti, R; Park, C; Sonnenblick, EH | 1 |
| Canepari, M; Cappelli, V; Micheletti, R; Reggiani, C; Zanardi, MC | 1 |
| Arrigoni-Martelli, E; Corsico, N; Mancinelli, R; Manni, E; Maresca, P | 2 |
| Amico-Roxas, M; Caruso, A; Cutuli, VM; De Bernardis, E; Leonardi, G | 2 |
| Bartlett, K; Bhuiyan, AK; Seccombe, D | 1 |
| Bertelli, A; Malengo, S; Palmieri, L; Ronca, F | 2 |
| Albano, O; Antonica, G; Berardi, E; Brevetti, G; Buonamico, P; Ferraioli, G; Godi, L; Sabbá, C | 1 |
| Bonta, IL; Elliott, GR; Garrelds, IM; Zijlstra, FJ | 1 |
| Kidouchi, K; Kobayashi, M; Matsuda, I; Narisawa, K; Sugiyama, N; Wada, Y | 1 |
| Mommessin, JI; Russell, RR; Taegtmeyer, H | 1 |
| Bertelli, A; Conte, A; Ronca, G | 1 |
| Brunelli, C; Canale, C; Caponnetto, S; Masperone, MA; Terracchini, V; Valentini, G | 1 |
| Boni, L; D'Ambrosio, G; Iliceto, S; Marangelli, V; Rizzon, P; Scrutinio, D | 1 |
| Bartels, GL; Kruijssen, DA; Pillay, M; Remme, WJ; Schönfeld, DH | 1 |
| Bianchi, G; Canepari, M; Giacalone, G; Micheletti, R; Reggiani, C; Salardi, S | 1 |
| Barbato, R; Di Lisa, F; Menabò, R; Siliprandi, N | 1 |
| Hassinen, IE; Peuhkurinen, KJ; Sundqvist, KE; Vuorinen, KH | 1 |
| De Maria, P; Fontana, A; Frascari, S; Gargaro, G; Spinelli, D; Tinti, MO | 1 |
| Cattapan, F; Magnanimi, L; Peschechera, A; Tassani, V | 1 |
| Fujioka, M; Kikawa, Y; Liu, YY; Nakai, A; Shigematsu, Y; Sudo, M | 1 |
| Hoppel, CL; Minkler, PE | 1 |
| Bertelli, A; Bertelli, AA; Galmozzi, G; Giovannini, L | 1 |
| Bertelli, A; Bertelli, AA; Galmozzi, G; Giovannini, L; Mian, M | 1 |
| Leopaldi, D; Riva, E | 1 |
| Brass, EP; Masterson, KA; Ruff, LJ; Scarrow, AM; Van Lunteren, E | 1 |
| Mancinelli, R | 1 |
| Arrigoni Martelli, E; Aureli, T; Conti, F; Corsico, N; Di Cocco, ME; Lucreziotti, MR; Miccheli, A; Nardone, A; Pesce, D; Spagnoli, LG | 1 |
| Bouhaddioni, N; el Alaoui-Talibi, Z; Moravec, J | 1 |
| Arduini, A; Arrigoni-Martelli, E; Dottori, S; Federici, G; Gorbunov, N; Molajoni, F; Russo, F | 1 |
| Chace, DH; Kahler, SG; Millington, DS; Van Hove, JL | 1 |
| Anversa, P; Benatti, P; Bianchi, G; Capasso, JM; Di Paola, ED; English, E; Micheletti, R; Schiavone, A | 1 |
| Davenport, RJ; Law, MP; Osman, S; Pike, VW; Poole, KG | 1 |
| Hamada, Y; Hara, T; Hotta, N; Koh, N; Mori, K; Nakamura, J; Nakashima, E; Naruse, K; Sakakibara, F; Sakamoto, N; Wakao, T | 1 |
| Böhles, HJ; Sewell, AC | 1 |
| Anversa, P; Bianchi, G; Ceppi, E; Cinato, E; Conti, F; Ferrari, P; Torielli, L | 1 |
| Fukasawa, H; Hamara, Y; Hara, T; Hotta, N; Kakuta, H; Koh, N; Nakamura, J; Nakashima, E; Sakakibara, F; Sakamoto, N; Sasaki, H | 1 |
| Bianchi, G; Donato di Paola, E; Micheletti, R; Rossi, R; Schiavone, A | 1 |
| Arduini, A; Arrigoni-Martelli, E; Calvani, M; Corsico, N; Dottori, S; Morabito, E; Sciarroni, AF | 1 |
| Boyd, H; Camici, PG; Cunningham, VJ; Davenport, RJ; Gunn, RN; Osman, S; Pike, VW; Rosen, SD | 1 |
| Bianchi, G; Giacalone, G; Micheletti, R | 1 |
| Mauriello, A; Orlandi, A; Perfumo, S; Sangiorgi, G; Schiaroli, S; Spagnoli, LG | 1 |
| Broderick, TL; Haloftis, G; Paulson, DJ | 1 |
| Bartels, GL; Holwerda, KJ; Kruijssen, DA; Remme, WJ | 1 |
| Burns, SP; Chalmers, RA; Iles, RA; Saudubray, JM | 1 |
| El Alaoui-Talibi, Z; Guendouz, A; Moravec, J; Moravec, M | 2 |
| Amato, B; Aprea, G; Cerfolio, P; Markabaoui, AK; Persico, G | 1 |
| Bartels, GL; den Hartog, FR; Kruijssen, DA; Remme, WJ; Wielenga, RP | 1 |
| Fukasawa, H; Hamada, Y; Hara, T; Hotta, N; Kakuta, H; Koh, N; Nakamura, J; Sakakibara, F; Sakamoto, N | 1 |
| Andreini, B; Bertelli, A; Giovannini, L; Migliori, M; Palla, R; Panichi, V | 1 |
| Andreini, B; Bertelli, A; Bertelli, AA; De Pietro, S; Giovannini, L; Migliori, M; Palla, R; Panichi, V | 1 |
| Bruno, G; Curti, S; Longo, A; Mancinelli, A; Miotto, G | 1 |
| Bianchi, G | 1 |
| Ferrari, R | 1 |
| Barletta, G; Brevetti, G; Di Iorio, A; Martone, VD; Perna, S; Sabba, C | 1 |
| Deckert, J | 1 |
| Irish, AB; Kemp, GJ; Radda, GK; Taylor, DJ; Thompson, CH | 1 |
| Azzena, G; Cittanti, C; Colamussi, P; Giganti, M; Manfrini, S; Orlandi, C; Piffanelli, A; Uccelli, L | 1 |
| Angelini, C; Brevetti, G; Carrozzo, R; De Amicis, V; Di Lello, F; Fanin, M; Martone, VD | 1 |
| Harris, J; Serjeant, BE; Serjeant, GR; Thomas, P | 1 |
| De Giuli, F; Ferrari, R | 1 |
| Davenport, RJ; Dowsett, K; Pike, VW; Poole, K; Turton, DR | 1 |
| Amico-Roxas, M; Christopher, TA; Guo, YP; Lopez, BL; Ma, XL; Stroh, R | 1 |
| Brogden, RN; Wiseman, LR | 1 |
| Capecchi, PL; Di Perri, T; Laghi Pasini, F; Quartarolo, E | 1 |
| Amato, A; Hands, LJ; Kemp, GJ; Nicolaides, A; Radda, GK; Ramaswami, G; Taylor, DJ | 1 |
| Andreini, B; De Pietro, S; Filippi, C; Giovannini, L; Migliori, M; Palla, R; Panichi, V; Taccola, D | 1 |
| Anand, I; Chandrashekhan, Y; Confortini, R; De Giuli, F; Ferrari, R; Mazzoletti, A; Pasini, E | 1 |
| Hotta, N; Koh, N; Matsubara, T; Nakamura, J; Terada, R | 1 |
| Brevetti, G; Corrado, S; Di Donato, AM; Di Iorio, A; Martone, VD; Silvestro, A | 1 |
| Dal Lago, A; De Martini, D; Flore, R; Gaetani, E; Gasbarrini, A; Gerardino, L; Nolfe, G; Pola, R; Santoliquido, A; Serricchio, M; Tondi, P | 1 |
| Amato, A; Cipolla, MJ; Nicoloff, A; Porter, JM; Rebello, T | 1 |
| Bertelli, A; Bertelli, AA; De Pietro, S; Giovannini, L; Migliori, M; Panichi, V; Taccola, D | 1 |
| Bertelli, A; Bertelli, AA; Giovannini, L; Longoni, B; Migliori, M | 1 |
| Battaglia, C; Brevetti, G; Gentile, M; Golino, P; Marone, G; Oriente, A; Triggiani, M | 1 |
| Dhalla, KS; Dhalla, NS; Ferrari, R; Ganguly, PK; Sethi, R | 1 |
| Brevetti, G; Diehm, C; Lambert, D | 1 |
| Grommisch, J; Gründer, W; Keller, T; Löster, H | 1 |
| Iacobazzi, V; Lasorsa, FM; Palmieri, F; Palmieri, L; Runswick, MJ; Walker, JE | 1 |
| El-Merzabani, MM; Khalifa, MH; Osman, AM; Rezk, BM; Sayed-Ahmed, MM; Shouman, SA | 1 |
| Carter, AL; Ganapathy, ME; Ganapathy, V; Huang, W; Iseki, K; Leibach, FH; Rajan, DP; Sugawara, M | 1 |
| Brivet, M; Roe, CR; Roe, DS; Sweetman, L | 1 |
| Barone, G; Costanza, G; Di Salvo, A; Marchese, G; Verruso, G; Zamueli, M | 1 |
| Aureli, T; Capuani, G; Cavallaro, A; Conti, F; Di Marzo, L; Giuliani, A; Miccheli, A; Mingoli, A; Sapienza, P; Tedesco, M | 1 |
| de Hoffmann, E; Libert, R; Nassogne, MC; Schanck, A; Thillaye, M; Van Hoof, F; Vincent, MF | 1 |
| Arrigoni-Martelli, E; Calvani, M; Reda, E | 1 |
| Broderick, TL; Driedzic, W; Paulson, DJ | 1 |
| Acquaviva, R; Barcellona, ML; Campisi, A; Di Giacomo, C; Russo, A; Sorrenti, V; Vanella, A | 1 |
| Evans, AM; Longo, A; Pace, S; Rolan, P; Toon, S | 1 |
| Evans, AM; Longo, A; Mancinelli, A; Nation, RL | 2 |
| Luca, S; Terranova, R | 1 |
| Hiatt, WR | 2 |
| Broderick, TL; Driedzic, WR; Felix, C; Gillis, M; Paulson, DJ | 1 |
| Amato, A; Cooke, JP; Creager, MA; Gorbunov, GN; Hiatt, WR; Hirsch, AT; Isner, J; Lukjanov, YV; Olin, JW; Regensteiner, JG; Tsitsiashvili, MS; Zabelskaya, TF | 1 |
| Lango, R; Lysiak-Szydlowska, W; Narkiewicz, M; Smolenski, RT; Suchorzewska, J | 1 |
| Abou El-Naga, SA; Calvani, M; Gaballah, HE; Nicolai, R; Salman, TM; Sayed-Ahmed, MM | 1 |
| Calvani, M; Capristo, E; Caso, V; De Gaetano, A; Gasbarrini, G; Giancaterini, A; Greco, AV; Mingrone, G | 1 |
| Askew, CD; Barker, GA; Green, AA; Green, S; Walker, PJ | 1 |
| Di Pino, L; Digrandi, D; Malaponte, G; Mazzarino, MC; Pennisi, G; Signorelli, SS | 1 |
| Chace, DH; DiPerna, JC; Johnson, RW; Kalas, TA; Naylor, EW | 1 |
| Calvani, M; Marcellini, M; Orlandi, A; Pesce, D; Spagnoli, LG | 1 |
| Doggrell, SA | 1 |
| Abbate, M; Aiello, S; Arduini, A; Azzollini, N; Gagliardini, E; Mister, M; Noris, M; Perico, N; Remuzzi, G; Szymczuk, J; Trochimowicz, L | 1 |
| Biagiotti, G; Cavallini, G; Koverech, A; Vitali, G | 1 |
| Carcassi, AM; Collu, M; Licheri, D; Littarru, GP; Mancinelli, R; Naimi, S; Vargiu, R | 1 |
| Kushnir, MM; Pasquali, M; Roberts, WL; Shushan, B | 1 |
| Endo, F; Inoue, Y; Ishimatu, J; Kuhara, T; Mitsubuchi, H; Ohse, M; Sakura, N; Yorifuji, T | 1 |
| Endo, F; Hirano, S; Kawai, M; Kuhara, T; Kurokawa, K; Mamada, M; Mitsubuchi, H; Muroi, J; Nakahata, T; Sakura, N; Shigematsu, Y; Yorifuji, T; Yoshida, I | 1 |
| Andreadou, I; Cicchitelli, G; Ferrari, R; Guardigli, G; Merli, E | 1 |
| Apstein, CS; Brenner, DA; Koh, SG; Korzick, DH; Saupe, KW; Tickerhoof, MM | 1 |
| Arafa, HM; Sayed-Ahmed, MM | 1 |
| Bertelli, A; Cui, J; Das, DK; Tosaki, A | 1 |
| Dhalla, NS; Ferrari, R; Sethi, R; Wang, X | 1 |
| Acerra, G; del Guercio, R; Fasano, C; Federico, P; Gioia, F; Madrid, E; Mattera, E; Ragozzino, G; Salomone, P | 1 |
| Broderick, TL; Gillis, M; Paulson, DJ | 1 |
| Di Silverio, F; Gentile, V; Koverech, A; Prigiotti, G; Vicini, P | 1 |
| Ceconi, C; Cicchitelli, G; Ferrari, R; Fucili, A; Mele, D; Merli, E | 1 |
| Badaloni, E; D'Acquarica, I; Galletti, B; Gasparrini, F; Giannoli, B; Giorgi, F; Tinti, MO; Vigevani, A | 1 |
| Durka, S; Heizmann, CW; Kleinert, P; Kuster, T; Neuheiser, F; Torresani, T; Troxler, H | 1 |
| Hasegawa, Y; Iga, M; Kimura, M; Shigematsu, Y; Yamaguchi, S | 1 |
| Alvarez de Sotomayor, M; Bueno, R; Gomez-Amores, L; Herrera, MD; Perez-Guerrero, C; Vazquez, CM | 1 |
| Lango, R; Lysiak-Szydłowska, W; Rogowski, J; Siebert, J; Smoleński, RT; Słomińska, EM; Wujtewicz, M; Yacoub, MH | 1 |
| Gómez-Amores, L; Mate, A; Revilla, E; Santa-María, C; Vázquez, CM | 1 |
| Cavallini, G; Koverech, A; Modenini, F; Vitali, G | 1 |
| Al-Majed, AA; Al-Rejaie, SS; Al-Shabanah, OA; Al-Yahya, AA; Aleisa, AM; Sayed-Ahmed, MM | 1 |
| Bene, J; Figler, M; Gasztonyi, B; Havasi, V; Horváth, K; Hunyady, B; Komlósi, K; Melegh, B; Mózsik, G; Talián, G | 1 |
| Gabriella, C; Gea, OC; Giuseppe, M; Giuseppe, P; Luigi, DP; Margherita, F; Massimiliano, A; Roberto, F; Santo, SS; Sergio, N | 1 |
| Campbell, CD; Ficicioglu, C; Ganesh, J | 1 |
| Bertelli, A; Carpi, A; Filippi, C; Giovannini, L; Migliori, M; Origlia, N; Panichi, V | 1 |
| Celotta, G; Di Pino, L; Fallico, R; Fatuzzo, P; Ferrante, M; Massimiliano, A; Neri, S; Oliveri Conti, G; Pennisi, G; Rapisarda, F; Signorelli, SS | 1 |
| Anzaldi, M; Celotta, G; Di Pino, L; Fallico, R; Fatuzzo, P; Ferrante, M; Neri, S; Oliveri Conti, G; Pennisi, G; Rapisarda, F; Signorelli, SS | 1 |
| Al-Majed, AA; Al-Omar, FA; Al-Shabanah, OA; Al-Yahya, AA; Aleisa, AM; Sayed-Ahmed, MM | 1 |
| Andreozzi, P; Cangemi, R; Loffredo, L; Meloni, V; Panico, MA; Pignatelli, P; Violi, F | 1 |
| Di Lascio, A; Francesconi, A; Marcellini, M; Orlandi, A; Spagnoli, LG | 1 |
| Al-Majed, AA | 1 |
| Cauli, A; Iliceto, S; Lai, S; Mathieu, A; Meloni, L; Montisci, M; Montisci, R; Passiu, G; Ruscazio, M; Vacca, A | 1 |
| Buchetti, B; Fallarino, M; Gandini, L; Gatti, A; Jannini, EA; Lenti, L; Lenzi, A; Mandosi, E; Morano, S; Sensi, M; Tiberti, C | 1 |
| Salonia, A | 1 |
| Pickard, R | 1 |
| Alvarez de Sotomayor, M; Bueno, R; Herrera, MD; Pérez-Guerrero, C | 1 |
| Donati, MA; Innocenti, M; la Marca, G; Malvagia, S; Pasquini, E; Zammarchi, E | 1 |
| de Sotomayor, MA; Herrera, MD; Marhuenda, E; Mingorance, C; Rodriguez-Rodriguez, R | 1 |
| Di Lascio, A; Ferlosio, A; Francesconi, A; Marcellini, M; Orlandi, A; Pisano, C; Spagnoli, LG | 1 |
| Hosseini, SY; Kolahi, AA; Safarinejad, MR | 1 |
| Barshop, BA; Gangoiti, JA; Siuzdak, G; Wikoff, WR | 1 |
| Al-Majed, AA; Al-Rejaie, SS; Al-Shabanah, OA; Al-Yahya, AA; Aleisa, AM; Bakheet, SA; Sayed-Ahmed, MM | 1 |
| de la Sierra García-Valdecasas, M; del Portal, LR; Delgado, C; Jiménez, LM; Macías, C; Pérez, M | 1 |
| Bloomer, RJ; Fry, AC; Smith, WA; Tschume, LC | 1 |
| Broderick, TL | 1 |
| Dong, JH; Hasegawa, Y; Liu, P; Qin, J; Sayami, S; Shi, CY; Song, JQ; Yamaguchi, S; Yan, R; Yang, YL; Zhang, Y | 1 |
| Copeland, S; Khanfar, N; Marble, M; Rosenblatt, DS | 1 |
| Izzo, A; Koverech, A; Liguori, M; Messano, M; Palermo, G; Riccioni, C; Sarcinella, R; Virmani, A | 1 |
| Bennett, MJ; Chapman, KA; Sondheimer, N | 1 |
| Abbate, M; Arduini, A; Azzollini, N; Cassis, P; Cugini, D; Gagliardini, E; Noris, M; Peschechera, A; Pezzotta, A; Remuzzi, G | 1 |
| Faa, G; Littarru, GP; Mancinelli, R; Vargiu, R | 1 |
| Cao, Y; Han, ZW; Liu, CJ; Wang, CB; Wang, LX; Wang, YX | 1 |
| Alvarez de Sotomayor, M; Dolores Herrera, M; Gonzalez del Pozo, M; Mingorance, C | 1 |
| Genova, C; Luigi Almasio, P; Milio, G; Novo, G; Novo, S; Pinto, A | 1 |
| Antonella Bertozzi, M; Antonini, G; Ashraf Virmani, M; Dinelli, N; Gentile, V; Koverech, A; Rizzo, C | 1 |
| Chen, PW; Chien, YH; Ho, MC; Hwu, WL; Lee, NC; Lee, PH; Ni, YH | 1 |
| Andreozzi, GM | 1 |
| Arcuri, G; Borsini, F; De Falco, S; Lombardo, K; Marcellini, M; Mattera, GG; Orlandi, A; Pisano, C; Riccioni, T; Scioli, MG; Spagnoli, LG; Stasi, MA | 1 |
| Chace, DH; De Jesús, VR; Hannon, WH; Lim, TH; Mei, JV | 1 |
| Bloomer, RJ; Smith, WA; Tschume, LC | 1 |
| Hata, I; Shigematsu, Y; Tajima, G | 1 |
| Chen, YJ; Cheng, KH; Chiang, CC; Ho, HJ; Hsiao, KJ; Huang, CH; Hung, PY; Hwu, WL; Kao, CH; Lee, NC; Lin, HY; Lin, JL; Lin, SP; Liu, MY; Liu, TT; Niu, DM | 1 |
| Gao, X; Gu, X; Han, L; Qiu, W; Wang, F; Wang, Y; Yang, Y; Ye, J; Zhang, H; Zhang, Y | 1 |
| Caliumi, C; Carloni, E; D'andrea, P; Izzo, A; Liguori, M; Palermo, G; Paolucci, AM; Pompili, S; Riccioni, C; Sarcinella, R | 1 |
| Canfield, SE; Dhir, RR; Lin, HC; Wang, R | 1 |
| Bentler, K; Hietala, A; Matern, D; Rodgers, J; Sarafoglou, K | 1 |
| Hozyasz, KK; Lugowska, I; Oltarzewski, M; Surowiec, Z; Szymanski, M | 1 |
| Alvarez de Sotomayor, M; Herrera, MD; Justo, ML; Mingorance, C; Rodríguez-Rodríguez, R | 1 |
| de Sotomayor, MA; Herrera, MD; Justo, ML; Mingorance, C; Rodriguez-Rodriguez, R | 1 |
| Brunner, M; Frimonti, E; Kletter, K; Longo, A; Müller, M; Pace, S; Pedrani, M; Rusca, A; Tschurlovits, M; Villa, R; Wagner, CC | 1 |
| Ardizzone, S; Bakulin, IG; Camerini, R; Ceracchi, M; D'Arienzo, A; Denapiene, G; Fociani, P; Gasbarrini, G; Grinevich, VB; Koch, M; Kupcinskas, L; Lesniakowski, K; Malecka-Panas, E; Mikhailova, TL; Poniewierka, E; Sishkova, E; Vago, G; Valpiani, D; Zerbi, P; Zhidkov, KP | 1 |
| De Larichaudy, J; Di Dato, C; Gianfrilli, D; Giannetta, E; Graziadio, C; Isidori, AM; Lauretta, R; Lenzi, A; Pozza, C | 1 |
| Bertini, G; Bollea, MR; Citro, G; Frascaria, T; Laviano, A; Molfino, A; Ramaccini, C; Rossi Fanelli, F; Seelaender, M | 1 |
| Fukuda, A; Horikawa, R; Ishige, M; Kakiuchi, T; Kanazawa, H; Karaki, C; Kasahara, M; Kosaki, R; Nagao, M; Naiki, Y; Nakazawa, A; Sakamoto, S; Shigematsu, Y; Shigeta, T; Yorifuji, T | 1 |
| Malaguarnera, M | 1 |
| Alvarez de Sotomayor, M; Andriantsitohaina, R; Chalopin, M; Ducluzeau, PH; Duluc, L; Herrera, MD; Mingorance, C; Simard, G | 1 |
| Donzelli, M; Fischer-Barnicol, D; Krähenbühl, S; Morand, R; Mullen, PJ; Todesco, L | 1 |
| Arosio, E; De Marchi, S; Fondrieschi, L; Prior, M; Rigoni, A; Rulfo, F; Scuro, A; Zecchetto, S | 1 |
| Arena, V; Cittadini, A; Fiore, F; Franceschi, F; Gasbarrini, A; Gasbarrini, G; Laterza, L; Merra, G; Pizzoferrato, M; Poscia, A; Scaldaferri, F; Sgambato, A | 1 |
| Amato, A; Brass, EP; Hiatt, WR; Koster, D | 1 |
| Gao, XL; Gu, XF; Han, LS; Li, XY; Qiu, WJ; Wang, Y; Wu, SN; Xu, H; Ye, J; Zhang, HW | 1 |
| Gao, XL; Gu, XF; Han, LS; Huang, Z; Ji, WJ; Li, XY; Qiu, WJ; Wang, Y; Ye, J; Zhang, HW | 1 |
| Gao, P; Huang, Q; Lu, X; Tan, Y; Wang, H; Xu, G; Ye, G; Yin, P | 1 |
| Auriola, S; Hanhineva, K; Huotari, A; Keski-Rahkonen, P; Kolehmainen, M; Lehtonen, M; Mykkänen, H; Olli, K; Pekkinen, J; Poutanen, K; Tiihonen, K | 1 |
| Moretti, S; Naccarato, A; Sindona, G; Tagarelli, A | 1 |
| Chen, Z; Jin, B; Li, J; Li, K; Li, L; Liu, C; Luo, T; Yang, B; Zhang, J; Zhang, X; Zheng, Q | 1 |
| Bouitbir, J; Felser, A; Frank, S; Handschin, C; Hench, J; Krähenbühl, S; Morand, R | 1 |
| Ametaj, BN; Dunn, SM; Hailemariam, D; Mandal, R; Saleem, F; Wishart, DS | 1 |
| Albano, L; Caterino, M; di Girolamo, MG; Di Stefano, C; Franzese, I; Gallo, G; Ingenito, L; Pecce, R; Ruoppolo, M; Scolamiero, E; Villani, GR | 1 |
| Agostinelli, S; Arcuri, G; Bielli, A; Costanza, G; Doldo, E; Ferlosio, A; Orlandi, A; Scioli, MG; Tarquini, C | 1 |
| Bogusiewicz, A; Boysen, G; Mock, DM | 1 |
| Barry, MA; Collard, R; Guenzel, AJ; Kraus, JP; Matern, D | 1 |
| Ding, Y; Li, X; Liu, Y; Song, J; Wang, H; Wang, Q; Wu, T; Yang, Y; Zhang, Y | 1 |
| Baumgartner, MR; Blom, HJ; Huemer, M; Kožich, V; Merinero, B; Pasquini, E; Ribes, A; Rinaldo, P | 1 |
| Dayaldasani, A; Pérez-Valero, V; Rodríguez-Espinosa, M; Rueda, I; Ruiz-Escalera, J; Yahyaoui, R | 1 |
| Gao, X; Gong, Z; Gu, X; Han, L; Jin, J; Qiu, W; Wang, Y; Wu, S; Ye, J; Zhang, H | 1 |
| Bao, WM; Chen, H; Cheng, JB; Li, W; Ma, LK; Tang, YM; Wang, JP; Xu, Y; Yang, J; Yang, JH; Yang, LH; Zhu, YP | 1 |
| Bielli, A; De Falco, S; De Rosa, A; Lo Giudice, P; Orlandi, A; Scioli, MG; Tarallo, V | 1 |
| Aukrust, P; Berge, RK; Damås, JK; Flo, TH; Landrø, L; Svardal, A; Ueland, T; Waagsbø, B; Øktedalen, O | 1 |
| Ding, Y; Li, DX; Li, XY; Liu, YP; Qin, YP; Song, JQ; Wang, Q; Yang, YL; Zhang, Y | 1 |
| Al-Dirbashi, OY; Chakraborty, P; McIntosh, N | 1 |
| Ayotte, P; Bienvenu, JF; Roy, C; Tremblay, PY | 1 |
| Baumgartner, MR; Burda, P; Devuyst, O; Fingerhut, R; Forny, P; Froese, DS; Heeren, J; Hornemann, T; Kölker, S; Langhans, CD; Mathis, D; Mustedanagic, M; Nägele, N; Peters, HL; Scheja, L; Schumann, A; Thony, B; Wulf, MA; Zhakupova, A | 1 |
| Endo, F; Inomata, Y; Kido, J; Matsumoto, S; Mitsubuchi, H; Nakamura, K; Sakamoto, R | 1 |
| Deng, Z; Jiang, Q; Li, C; Wang, C; Wang, M; Wang, Q; Xue, C; Xue, L | 1 |
| Heggermont, WA; Heymans, S; Papageorgiou, AP; van Bilsen, M | 1 |
| Cooper, C; Dennison, EM; Edwards, MH; Geisendorfer, T; Huber, A; Jarvelin, MR; Karhunen, V; Menni, C; Metrustry, SJ; Reichel, C; Spector, T; Valdes, AM | 1 |
| Brotzu, G; Campisi, M; Consolaro, F; Fadda, AM; Manca, ML; Manca, T; Marongiu, F | 1 |
| Barić, I; Bártl, J; Baumgartner, MR; Ben-Omran, T; Blasco-Alonso, J; Blom, HJ; Bueno Delgado, MA; Carducci, C; Cassanello, M; Cerone, R; Chrastina, P; Couce, ML; Crushell, E; Delgado Pecellin, C; Dionisi-Vici, C; Dulin, E; Espada, M; Ferino, G; Fingerhut, R; Garcia Jimenez, I; Gleich, F; Gonzalez Gallego, I; González-Irazabal, Y; Gouveia, S; Gramer, G; Huemer, M; Juan Fita, MJ; Karg, E; Keller, R; Klein, J; Kölker, S; Konstantopoulou, V; Kožich, V; la Marca, G; Leão Teles, E; Leuzzi, V; Lilliu, F; Lopez, RM; Lund, AM; Mayne, P; Meavilla, S; Moat, SJ; Morris, AA; Okun, JG; Pasquini, E; Pavlíková, M; Pedron-Giner, CC; Racz, GZ; Ribes, A; Ruiz Gomez, MA; Vilarinho, L; Yahyaoui, R; Zerjav Tansek, M; Zetterström, RH; Zeyda, M | 1 |
| Dicksved, J; Hagman, R; Höglund, K; Moazzami, AA; Östman, JR; Söder, J; Wernersson, S | 1 |
| Hu, L; Hu, Z; Huang, X; Lin, Y; Wang, J; Yang, J; Zhang, C; Zhang, Y | 1 |
| Blessing, H; Lotz-Havla, AS; Maier, EM; Röschinger, W; Schiergens, KA; Weiss, KJ | 1 |
| Chen, LQ; Chen, RY; Chen, XQ; Li, XZ; Lin, Q; Shen, YY; Wu, HY; Xu, QY; Zhu, XM; Zhu, Y | 1 |
| Águas, R; Mota, SI; Pereira, FC; Pita, I; Rego, AC; Tagorti, S; Virmani, A | 1 |
| Chen, T; Ding, S; Gu, X; Han, L; Liang, L; Ling, S; Qiu, W; Xu, F; Zhan, X; Zhang, H | 1 |
| Lee, YH; Park, S | 1 |
20 review(s) available for carnitine and propionylcarnitine
| Article | Year |
|---|---|
Propionyl-L-carnitine: biochemical significance and possible role in cardiac metabolism.
Topics: Acyl Coenzyme A; Animals; Carnitine; Humans; Mitochondria, Heart; Propionates | 1991 |
Transport and function of L-carnitine and L-propionylcarnitine: relevance to some cardiomyopathies and cardiac ischemia.
Topics: Animals; Biological Transport; Cardiomyopathies; Carnitine; Coronary Disease; Humans; Myocardium; Sarcolemma | 1987 |
Acylcarnitines in intermediary metabolism.
Topics: Acylation; Cardiomyopathies; Cardiotonic Agents; Carnitine; Humans; Metabolic Diseases | 1995 |
The propionyl-L-carnitine hypothesis: an alternative approach to treating heart failure.
Topics: Animals; Cardiotonic Agents; Carnitine; Chronic Disease; Disease Models, Animal; Heart; Heart Failure; Humans; Models, Biological; Muscles; Rabbits; Rats | 1997 |
Propionyl-L-carnitine.
Topics: Aged; Arterial Occlusive Diseases; Cardiotonic Agents; Carnitine; Clinical Trials as Topic; Humans; Muscle, Skeletal | 1998 |
Regulation by carnitine of myocardial fatty acid and carbohydrate metabolism under normal and pathological conditions.
Topics: Animals; Carbohydrate Metabolism; Carnitine; Fatty Acids; Humans; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Oxidation-Reduction | 2000 |
New treatment options in intermittent claudication: the US experience.
Topics: Arginine; Carnitine; Cilostazol; Endothelial Growth Factors; Exercise Therapy; Humans; Intermittent Claudication; Multicenter Studies as Topic; Nafronyl; Pentoxifylline; Phosphodiesterase Inhibitors; Prostaglandins; Quality of Life; Randomized Controlled Trials as Topic; Serotonin Antagonists; Tetrazoles; United States | 2001 |
Influence of L-carnitine and its derivatives on myocardial metabolism and function in ischemic heart disease and during cardiopulmonary bypass.
Topics: Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Cardiopulmonary Bypass; Carnitine; Energy Metabolism; Glucose; Humans; Kidney; Myocardial Ischemia; Myocardium; Thrombosis | 2001 |
Pharmacotherapy of intermittent claudication.
Topics: Animals; Anticoagulants; Cardiotonic Agents; Carnitine; Cilostazol; Humans; Intermittent Claudication; Nafronyl; Nitric Oxide; Pentoxifylline; Platelet Aggregation Inhibitors; Tetrazoles; Vasodilator Agents | 2001 |
Metabolic modulation and optimization of energy consumption in heart failure.
Topics: Acetanilides; Cardiac Pacing, Artificial; Cardiotonic Agents; Carnitine; Energy Metabolism; Heart Failure; Humans; Piperazines; Ranolazine; Trimetazidine | 2003 |
Therapeutic effects of L-carnitine and propionyl-L-carnitine on cardiovascular diseases: a review.
Topics: Cardiotonic Agents; Cardiovascular Diseases; Carnitine; Humans; Kidney Failure, Chronic; Liver; Myocardial Ischemia; Valproic Acid | 2004 |
Carnitine and peripheral arterial disease.
Topics: Arterial Occlusive Diseases; Carnitine; Humans; Intermittent Claudication; Muscle, Skeletal; Oxygen Consumption | 2004 |
Propionyl l-carnitine: intermittent claudication and peripheral arterial disease.
Topics: Cardiotonic Agents; Carnitine; Exercise; Humans; Intermittent Claudication; Peripheral Vascular Diseases | 2009 |
Combination therapy for erectile dysfunction: an update review.
Topics: Adrenergic alpha-Antagonists; Adult; Aged; Alprostadil; Carnitine; Combined Modality Therapy; Erectile Dysfunction; Humans; Male; Middle Aged; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones; Vacuum | 2011 |
Critical update for the clinical use of L-carnitine analogs in cardiometabolic disorders.
Topics: Acetylcarnitine; Animals; Cardiovascular Agents; Cardiovascular Diseases; Carnitine; Diabetes Mellitus, Type 2; Evidence-Based Medicine; Humans; Hypoglycemic Agents; Insulin Resistance; Treatment Outcome | 2011 |
Pharmacological effects and clinical applications of propionyl-L-carnitine.
Topics: Adenosine Triphosphate; Atherosclerosis; Carbohydrate Metabolism; Cardiotonic Agents; Carnitine; Endothelium; Free Radical Scavengers; Heart; Humans; Insulin Resistance; Lipid Metabolism; Oxidative Stress | 2011 |
Carnitine derivatives: clinical usefulness.
Topics: Acetylcarnitine; Cardiotonic Agents; Cardiovascular Diseases; Carnitine; Cognition Disorders; Depression; Diabetes Mellitus; Humans; Liver Cirrhosis; Nervous System Diseases; Nootropic Agents | 2012 |
A systematic review and meta-analysis of propionyl-L-carnitine effects on exercise performance in patients with claudication.
Topics: Carnitine; Clinical Trials as Topic; Exercise Test; Humans; Intermittent Claudication; Walking | 2013 |
Newborn screening for homocystinurias and methylation disorders: systematic review and proposed guidelines.
Topics: Acetylcarnitine; Betaine; Carnitine; Homocystinuria; Humans; Infant, Newborn; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Neonatal Screening; Practice Guidelines as Topic | 2015 |
Metabolic support for the heart: complementary therapy for heart failure?
Topics: Acetyl-CoA C-Acyltransferase; Cardiovascular Agents; Carnitine; Carnitine O-Palmitoyltransferase; Dichloroacetic Acid; Energy Metabolism; Enzyme Inhibitors; Epoxy Compounds; Fatty Acids; Glucose; Heart Failure; Humans; Myocardium; Myocytes, Cardiac; Oxidation-Reduction; Perhexiline; Ranolazine; Stroke Volume; Trimetazidine | 2016 |
56 trial(s) available for carnitine and propionylcarnitine
| Article | Year |
|---|---|
Controlled study on the therapeutic efficacy of propionyl-L-carnitine in patients with congestive heart failure.
Topics: Aged; Carnitine; Double-Blind Method; Exercise Test; Female; Heart Failure; Humans; Male; Middle Aged; Ultrasonography | 1992 |
[The clinical and hemodynamic effects of propionyl-L-carnitine in the treatment of congestive heart failure].
Topics: Aged; Cardiotonic Agents; Carnitine; Double-Blind Method; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged | 1992 |
Superiority of L-propionylcarnitine vs L-carnitine in improving walking capacity in patients with peripheral vascular disease: an acute, intravenous, double-blind, cross-over study.
Topics: Arterial Occlusive Diseases; Carnitine; Dose-Response Relationship, Drug; Double-Blind Method; Exercise Test; Hemodynamics; Humans; Infusions, Intravenous; Intermittent Claudication; Ischemia; Leg; Male; Middle Aged | 1992 |
Evaluation of the therapeutic efficacy and tolerability of levocarnitine propionyl in the treatment of chronic obstructive arteriopathies of the lower extremities: a multicentre controlled study vs. placebo.
Topics: Administration, Oral; Aged; Analysis of Variance; Arterial Occlusive Diseases; Arteriosclerosis; Carnitine; Diabetic Angiopathies; Female; Humans; Intermittent Claudication; Male; Middle Aged; Patient Compliance; Regression Analysis; Stereoisomerism | 1992 |
Effect of propionyl-L-carnitine in the treatment of diabetic angiopathy: controlled double blind trial versus placebo.
Topics: Administration, Oral; Aged; Analysis of Variance; Carnitine; Diabetic Angiopathies; Double-Blind Method; Female; Humans; Male; Middle Aged; Ultrasonography; Walking | 1992 |
Propionyl-L-carnitine: a new compound in the metabolic approach to the treatment of effort angina.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Carnitine; Coronary Disease; Double-Blind Method; Exercise Test; Female; Heart Rate; Humans; Male; Middle Aged; Myocardium; Oxygen Consumption | 1992 |
Propionyl carnitine in stable effort angina.
Topics: Administration, Oral; Adult; Aged; Angina Pectoris; Blood Pressure; Carnitine; Double-Blind Method; Electrocardiography; Exercise Test; Heart Rate; Humans; Male; Middle Aged; Time Factors | 1990 |
[Acute effects of propionyl-L-carnitine on anomalies of parietal kinetics of the left ventricle induced by atrial pacing in patients with ischemic heart disease. A bidimensional echocardiographic study].
Topics: Adult; Cardiac Pacing, Artificial; Carnitine; Coronary Disease; Double-Blind Method; Echocardiography; Heart; Humans; Male; Middle Aged; Randomized Controlled Trials as Topic; Stroke Volume | 1989 |
Propionyl-L-carnitine in intermittent claudication: double-blind, placebo-controlled, dose titration, multicenter study.
Topics: Administration, Oral; Analysis of Variance; Cardiotonic Agents; Carnitine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Intermittent Claudication; Male; Middle Aged; Treatment Outcome | 1995 |
L-propionylcarnitine effect on postexercise and postischemic hyperemia in patients affected by peripheral vascular disease.
Topics: Aged; Blood Flow Velocity; Carnitine; Cross-Over Studies; Double-Blind Method; Humans; Hyperemia; Injections, Intravenous; Intermittent Claudication; Ischemia; Leg; Male; Middle Aged; Physical Exertion | 1995 |
Comparison between the effect of L-propionylcarnitine, L-acetylcarnitine and nitroglycerin in chronic peripheral arterial disease: a haemodynamic double blind echo-Doppler study.
Topics: Acetylcarnitine; Blood Flow Velocity; Cardiotonic Agents; Carnitine; Child, Preschool; Cross-Over Studies; Double-Blind Method; Femoral Artery; Hemodynamics; Humans; Male; Middle Aged; Nitroglycerin; Peripheral Vascular Diseases; Ultrasonography, Doppler, Pulsed | 1994 |
Efficacy of L-propionylcarnitine treatment in patients with left ventricular dysfunction.
Topics: Adult; Aged; Cardiotonic Agents; Carnitine; Double-Blind Method; Echocardiography, Doppler; Exercise Test; Female; Humans; Lactates; Lactic Acid; Male; Middle Aged; Pyruvates; Pyruvic Acid; Stroke Volume; Ventricular Dysfunction, Left | 1994 |
Effects of L-propionylcarnitine on ischemia-induced myocardial dysfunction in men with angina pectoris.
Topics: Aged; Angina Pectoris; Cardiac Output; Cardiotonic Agents; Carnitine; Coronary Disease; Electrocardiography; Exercise Test; Heart; Heart Rate; Humans; Hypoxanthine; Hypoxanthines; Lactates; Male; Middle Aged; Myocardial Contraction; Myocardial Ischemia; Placebos; Stroke Volume; Ventricular Function, Left; Ventricular Pressure | 1994 |
Anti-ischaemic efficacy of L-propionylcarnitine--a promising novel metabolic approach to ischaemia?
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Cardiotonic Agents; Cardiovascular Agents; Carnitine; Cross-Over Studies; Diltiazem; Double-Blind Method; Electrocardiography, Ambulatory; Exercise Test; Female; Heart Rate; Humans; Male; Middle Aged; Treatment Outcome | 1996 |
Propionylcarnitine excretion is not affected by metronidazole administration to patients with disorders of propionate metabolism.
Topics: Amino Acid Metabolism, Inborn Errors; Antitrichomonal Agents; Carnitine; Child, Preschool; Humans; Infant; Magnetic Resonance Spectroscopy; Methylmalonic Acid; Metronidazole; Propionates | 1996 |
The early effects of intravenous L-propionyl carnitine on ulcerative trophic lesions of the lower limbs in arteriopathic patients: a controlled randomized study.
Topics: Aged; Aged, 80 and over; Amputation, Surgical; Anti-Inflammatory Agents, Non-Steroidal; Arterial Occlusive Diseases; Blood Coagulation; Carnitine; Female; Humans; Infusions, Intravenous; Ketoprofen; Leg Ulcer; Male; Middle Aged; Peripheral Vascular Diseases; Regional Blood Flow | 1995 |
Additional antiischemic effects of long-term L-propionylcarnitine in anginal patients treated with conventional antianginal therapy.
Topics: Adult; Aged; Angina Pectoris; Carnitine; Exercise Test; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Single-Blind Method | 1995 |
Effect of propionyl-L-carnitine on quality of life in intermittent claudication.
Topics: Aged; Cardiotonic Agents; Carnitine; Double-Blind Method; Female; Humans; Intermittent Claudication; Italy; Male; Middle Aged; Quality of Life; Surveys and Questionnaires; Time Factors; Walking | 1997 |
Propionyl-L-carnitine for intermittent claudication.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Attitude to Health; Carnitine; Double-Blind Method; Emotions; Exercise Test; Female; Follow-Up Studies; Humans; Intermittent Claudication; Male; Placebos; Quality of Life; Walking | 1997 |
Technetium-99m sestamibi leg scintigraphy for non-invasive assessment of propionyl-L-carnitine induced changes in skeletal muscle metabolism.
Topics: Arterial Occlusive Diseases; Carnitine; Female; Humans; Leg; Male; Middle Aged; Muscle, Skeletal; Peripheral Vascular Diseases; Radionuclide Imaging; Radiopharmaceuticals; Technetium Tc 99m Sestamibi; Ultrasonography, Doppler | 1997 |
Changes in skeletal muscle histology and metabolism in patients undergoing exercise deconditioning: effect of propionyl-L-carnitine.
Topics: Carnitine; Conditioning, Psychological; Coronary Disease; Exercise; Glycogen; Humans; Male; Middle Aged; Muscle Fibers, Skeletal; Muscle, Skeletal; Reference Values | 1997 |
Propionyl-L-carnitine in chronic leg ulcers of homozygous sickle cell disease: a pilot study.
Topics: Adolescent; Adult; Anemia, Sickle Cell; Carnitine; Chronic Disease; Double-Blind Method; Female; Homozygote; Humans; Leg Ulcer; Male; Organization and Administration; Pilot Projects | 1997 |
Changes in energy metabolism of calf muscle in patients with intermittent claudication assessed by 31P magnetic resonance spectroscopy: a phase II open study.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adult; Aged; Aged, 80 and over; Carnitine; Energy Metabolism; Female; Humans; Intermittent Claudication; Leg; Magnetic Resonance Spectroscopy; Male; Middle Aged; Muscle, Skeletal; Phosphocreatine; Phosphorus; Walking | 1996 |
Acute and chronic effects of propionyl-L-carnitine on the hemodynamics, exercise capacity, and hormones in patients with congestive heart failure.
Topics: Adult; Cardiotonic Agents; Carnitine; Echocardiography; Exercise Tolerance; Female; Heart Failure; Hemodynamics; Hormones; Humans; Male; Middle Aged; Neurosecretory Systems; Oxygen Consumption; Single-Blind Method; Time Factors; Ventricular Function | 1998 |
Study on propionyl-L-carnitine in chronic heart failure.
Topics: Angiotensin-Converting Enzyme Inhibitors; Cardiotonic Agents; Carnitine; Chronic Disease; Diuretics; Double-Blind Method; Drug Therapy, Combination; Exercise Test; Female; Follow-Up Studies; Heart Failure; Humans; Male; Middle Aged; Quality of Life; Retrospective Studies; Stroke Volume; Survival Rate; Treatment Outcome | 1999 |
Effects of propionyl-L-carnitine on peripheral arterial obliterative disease of the lower limbs: a double-blind clinical trial.
Topics: Adult; Aged; Arterial Occlusive Diseases; Cardiotonic Agents; Carnitine; Double-Blind Method; Exercise Test; Female; Humans; Intermittent Claudication; Leg; Male; Middle Aged; Placebos | 1999 |
Inhibition of platelet-activating factor synthesis in human neutrophils and platelets by propionyl-L-carnitine.
Topics: Adult; Arachidonic Acids; Blood Platelets; Cardiotonic Agents; Carnitine; Eicosanoids; Humans; In Vitro Techniques; Ischemia; Male; Middle Aged; Neutrophils; Platelet Activating Factor | 1999 |
European multicenter study on propionyl-L-carnitine in intermittent claudication.
Topics: Cardiotonic Agents; Carnitine; Double-Blind Method; Europe; Female; Humans; Intermittent Claudication; Male; Middle Aged; Prospective Studies; Quality of Life; Treatment Outcome | 1999 |
[Comparison between L-propionyl carnitine and physical-rehabilitative exercise in diabetics with obliterative arteriopathy of the legs (Fontaine's stage IIa)].
Topics: Arterial Occlusive Diseases; Cardiotonic Agents; Carnitine; Diabetic Angiopathies; Female; Humans; Leg; Male; Middle Aged | 1999 |
31Phosphorus magnetic resonance spectroscopy to evaluate medical therapy efficacy in peripheral arterial disease. A pilot study.
Topics: Aged; Animals; Carnitine; Double-Blind Method; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Muscle, Skeletal; Peripheral Vascular Diseases; Phosphorus | 1999 |
Pharmacokinetics of propionyl-L-carnitine in humans: evidence for saturable tubular reabsorption.
Topics: Absorption; Acetylcarnitine; Adolescent; Adult; Cardiotonic Agents; Carnitine; Creatinine; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Infusions, Intravenous; Kidney Tubules; Male; Middle Aged; Placebos | 2000 |
Propionyl-L-carnitine improves exercise performance and functional status in patients with claudication.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Carnitine; Double-Blind Method; Exercise Tolerance; Female; Humans; Intermittent Claudication; Male; Middle Aged | 2001 |
Effects of propyonil-l-carnitine topical irrigation in distal ulcerative colitis: a preliminary report.
Topics: Administration, Topical; Adult; Carnitine; Colitis, Ulcerative; Enema; Humans; Male; Therapeutic Irrigation | 2001 |
Effect of propionyl-L-carnitine on exercise performance in peripheral arterial disease.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Carnitine; Exercise; Female; Humans; Intermittent Claudication; Male; Middle Aged; Muscle, Skeletal; Peripheral Vascular Diseases; Physical Endurance; Single-Blind Method; Treatment Outcome; Walking | 2001 |
Effects of ischaemic stress on leukocyte activation processes in patients with chronic peripheral occlusive arterial disease: role of L-propionyl carnitine administration.
Topics: Aged; Arteriosclerosis; Cardiotonic Agents; Carnitine; Cell Adhesion Molecules; Chronic Disease; E-Selectin; Exercise; Exercise Test; Humans; Intercellular Adhesion Molecule-1; Ischemia; L-Selectin; Middle Aged; P-Selectin; Vascular Cell Adhesion Molecule-1 | 2001 |
Oral propionyl-l-carnitine and intraplaque verapamil in the therapy of advanced and resistant Peyronie's disease.
Topics: Administration, Oral; Adult; Aged; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Carnitine; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; Humans; Injections, Intralesional; Male; Middle Aged; Penile Induration; Prospective Studies; Verapamil | 2002 |
Effects of propionyl-carnitine in patients with type 2 diabetes and peripheral vascular disease: results of a pilot trial.
Topics: Blood Glucose; Carnitine; Diabetes Mellitus, Type 2; Female; Humans; Injections, Intravenous; Male; Middle Aged; Peripheral Vascular Diseases; Pilot Projects; Treatment Outcome; Vasodilator Agents | 2004 |
Preliminary observations on the use of propionyl-L-carnitine in combination with sildenafil in patients with erectile dysfunction and diabetes.
Topics: Carnitine; Diabetes Complications; Double-Blind Method; Drug Therapy, Combination; Erectile Dysfunction; Humans; Male; Middle Aged; Penile Erection; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones | 2004 |
Propionyl-L-carnitine improves hemodynamics and metabolic markers of cardiac perfusion during coronary surgery in diabetic patients.
Topics: Aged; Blood Pressure; Cardiopulmonary Bypass; Cardiotonic Agents; Carnitine; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Humans; Hypoxanthine; Lactic Acid; Male; Middle Aged; Muscle, Skeletal; Myocardium | 2005 |
Acetyl-L-carnitine plus propionyl-L-carnitine improve efficacy of sildenafil in treatment of erectile dysfunction after bilateral nerve-sparing radical retropubic prostatectomy.
Topics: Acetylcarnitine; Carnitine; Drug Therapy, Combination; Erectile Dysfunction; Humans; Male; Middle Aged; Piperazines; Prospective Studies; Prostate; Prostatectomy; Purines; Sildenafil Citrate; Sulfones | 2005 |
Effect of PLC on functional parameters and oxidative profile in type 2 diabetes-associated PAD.
Topics: Aged; Aldehydes; Ankle; Blood Glucose; Blood Pressure; Brachial Artery; Carnitine; Cholesterol, LDL; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Double-Blind Method; Glycated Hemoglobin; Humans; Malondialdehyde; Middle Aged; Oxidation-Reduction; Pain Measurement; Placebos | 2006 |
A randomised, controlled clinical trial evaluating changes in therapeutic efficacy and oxidative parameters after treatment with propionyl L-carnitine in patients with peripheral arterial disease requiring haemodialysis.
Topics: Aged; Aldehydes; Carnitine; Double-Blind Method; Humans; Malondialdehyde; Middle Aged; Nitrates; Nitrites; Oxygen; Peripheral Vascular Diseases; Placebos; Renal Dialysis; Renal Insufficiency | 2006 |
Propionyl-L-carnitine therapy: effects on endothelin-1 and homocysteine levels in patients with peripheral arterial disease and end-stage renal disease.
Topics: Ankle; Branchial Region; Carnitine; Double-Blind Method; Endothelin-1; Homocysteine; Humans; Infusions, Intravenous; Kidney Failure, Chronic; Peripheral Vascular Diseases; Placebos; Renal Dialysis | 2006 |
Imbalance between nitric oxide generation and oxidative stress in patients with peripheral arterial disease: effect of an antioxidant treatment.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Arterial Occlusive Diseases; Carnitine; Cross-Sectional Studies; Deoxyguanosine; Female; Humans; Male; Middle Aged; Nitric Oxide; Oxidative Stress | 2006 |
Effect of a single IV administration of L-propionylcarnitine on myocardial microcirculation assessed by coronary flow velocity reserve measurement in patients with systemic sclerosis: a pilot study.
Topics: Adenosine; Adult; Aged; Blood Flow Velocity; Cardiotonic Agents; Cardiovascular Diseases; Carnitine; Coronary Circulation; Coronary Vessels; Echocardiography, Doppler; Female; Humans; Injections, Intravenous; Male; Microcirculation; Middle Aged; Myocardium; Pilot Projects; Scleroderma, Systemic | 2007 |
Antioxidant treatment associated with sildenafil reduces monocyte activation and markers of endothelial damage in patients with diabetic erectile dysfunction: a double-blind, placebo-controlled study.
Topics: Aged; Antioxidants; Biomarkers; Carnitine; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Endothelium, Vascular; Erectile Dysfunction; Glycated Hemoglobin; Humans; Male; Middle Aged; Monocytes; Phosphodiesterase Inhibitors; Piperazines; Purines; Reactive Oxygen Species; Sildenafil Citrate; Sulfones | 2007 |
Comparison of vitamin E and propionyl-L-carnitine, separately or in combination, in patients with early chronic Peyronie's disease: a double-blind, placebo controlled, randomized study.
Topics: Administration, Oral; Adult; Carnitine; Double-Blind Method; Drug Therapy, Combination; Follow-Up Studies; Humans; Male; Middle Aged; Pain Measurement; Penile Erection; Penile Induration; Ultrasonography; Vitamin E | 2007 |
Effect of glycine propionyl-L-carnitine on aerobic and anaerobic exercise performance.
Topics: Adolescent; Adult; Carnitine; Dietary Supplements; Double-Blind Method; Exercise; Female; Glycine; Humans; Male; Muscle, Skeletal; Oxygen Consumption; Physical Endurance | 2008 |
Evaluation of the efficacy of propionyl-L-carnitine versus pulsed muscular compressions in diabetic and non-diabetic patients affected by obliterating arteriopathy Leriche stage II.
Topics: Aged; Arterial Occlusive Diseases; Cardiovascular Agents; Carnitine; Combined Modality Therapy; Diabetes Mellitus, Type 2; Female; Humans; Infusions, Intravenous; Intermittent Claudication; Intermittent Pneumatic Compression Devices; Male; Middle Aged; Quality of Life; Recovery of Function; Severity of Illness Index; Time Factors; Treatment Outcome; Walking | 2008 |
Pharmacological treatment of patients with chronic critical limb ischemia: L-propionyl-carnitine enhances the short-term effects of PGE-1.
Topics: Aged; Alprostadil; Cardiotonic Agents; Carnitine; Chronic Disease; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Ischemia; Leg; Leg Ulcer; Male; Middle Aged; Pain; Treatment Outcome; Vasodilator Agents; Walking | 2009 |
Effect of propionyl-L-carnitine, L-arginine and nicotinic acid on the efficacy of vardenafil in the treatment of erectile dysfunction in diabetes.
Topics: Arginine; Carnitine; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Erectile Dysfunction; Humans; Imidazoles; Male; Middle Aged; Niacin; Penile Erection; Piperazines; Placebos; Sulfones; Surveys and Questionnaires; Treatment Outcome; Triazines; Vardenafil Dihydrochloride; Vasodilator Agents | 2009 |
Glycine propionyl-L-carnitine modulates lipid peroxidation and nitric oxide in human subjects.
Topics: Adolescent; Adult; Blood Cell Count; Blood Chemical Analysis; Carnitine; Cholesterol; Double-Blind Method; Exercise; Glycine; Humans; Lipid Metabolism; Malondialdehyde; Nitric Oxide; Triglycerides; Young Adult | 2009 |
Plasma pharmacokinetics and gastrointestinal transit of a new propionyl-L-carnitine controlled release formulation.
Topics: Administration, Oral; Adolescent; Adult; Carnitine; Delayed-Action Preparations; Demography; Dose-Response Relationship, Drug; Gastrointestinal Transit; Humans; Male; Middle Aged; Radionuclide Imaging; Time Factors; Young Adult | 2011 |
Randomised clinical trial: the efficacy and safety of propionyl-L-carnitine therapy in patients with ulcerative colitis receiving stable oral treatment.
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Carnitine; Cohort Studies; Colitis, Ulcerative; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Severity of Illness Index; Treatment Outcome; Young Adult | 2011 |
Propionyl-L-carnitine improves endothelial function, microcirculation and pain management in critical limb ischemia.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Blood Gas Monitoring, Transcutaneous; Brachial Artery; Carnitine; Endothelium, Vascular; Female; Humans; Ischemia; Laser-Doppler Flowmetry; Leg; Male; Microcirculation; Pain Management; Peripheral Arterial Disease; Regional Blood Flow; Vasodilation | 2012 |
A study on the efficacy and safety assessment of propionyl-L-carnitine tablets in treatment of intermittent claudication.
Topics: Administration, Oral; Aged; Carnitine; Double-Blind Method; Humans; Intermittent Claudication; Middle Aged; Pentoxifylline; Peripheral Arterial Disease; Treatment Outcome; Walking | 2013 |
254 other study(ies) available for carnitine and propionylcarnitine
| Article | Year |
|---|---|
Functional characteristics and tissue distribution pattern of organic cation transporter 2 (OCTN2), an organic cation/carnitine transporter.
Topics: Acetylcarnitine; Animals; Biological Transport, Active; Carnitine; Carrier Proteins; Humans; In Situ Hybridization; Kidney; Membrane Proteins; Mice; Myocardium; Organ Specificity; Organic Cation Transport Proteins; Placenta; Rats; RNA, Messenger; Solute Carrier Family 22 Member 5; Tetraethylammonium | 1999 |
Inhibition of histamine release and pressure increase induced by endothelin (ET-1) in isolated rat kidneys treated with propionyl carnitine.
Topics: Animals; Blood Pressure; Cardiotonic Agents; Carnitine; Endothelins; Histamine Release; In Vitro Techniques; Kidney; Male; Prostaglandins; Rats; Rats, Wistar; Renal Circulation | 1992 |
The action of propionyl-L-carnitine on the vasal endothelium: increased t-PA synthesis and a decrease in the activity of PAI-1. A preliminary study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Cardiotonic Agents; Carnitine; Endothelium, Vascular; Female; Humans; Male; Middle Aged; Plasminogen Activator Inhibitor 1; Plasminogen Activators; Vascular Diseases | 1992 |
Effect of propionyl-L-carnitine on experimental induced cardiomyopathy in rats.
Topics: Animals; Blood Pressure; Cardiomyopathies; Carnitine; Diabetes Mellitus, Experimental; Erucic Acids; Heart; Hemodynamics; In Vitro Techniques; Male; Rats; Rats, Sprague-Dawley; Reference Values | 1992 |
Protection of isolated perfused working rat heart from oxidative stress by exogenous L-propionyl carnitine.
Topics: Animals; Cardiotonic Agents; Carnitine; Catalase; Cattle; Drug Interactions; Heart; Hemodynamics; Hydrogen Peroxide; Liver; Male; Myocardium; Oxidation-Reduction; Perfusion; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 1992 |
Antiradical effects in L-propionyl carnitine protection of the heart against ischemia-reperfusion injury: the possible role of iron chelation.
Topics: Animals; Carnitine; Deferoxamine; Electron Spin Resonance Spectroscopy; Energy Metabolism; Free Radical Scavengers; Free Radicals; Hydroxides; Hydroxyl Radical; Iron Chelating Agents; Luminescent Measurements; Luminol; Male; Myocardial Reperfusion Injury; Oxidation-Reduction; Rats; Rats, Inbred Strains; Stereoisomerism; Superoxides; Ventricular Function, Left | 1992 |
Acute improvement of cardiac function with intravenous L-propionylcarnitine in humans.
Topics: Aged; Angina Pectoris; Blood Pressure; Carnitine; Coronary Disease; Female; Hemodynamics; Humans; Injections, Intravenous; Male; Middle Aged; Myocardial Contraction; Myocardium; Oxygen Consumption; Stroke Volume | 1992 |
Hemodynamic and metabolic activities of propionyl-L-carnitine in rats with pressure-overload cardiac hypertrophy.
Topics: Adenine Nucleotides; Analysis of Variance; Animals; Blood Pressure; Cardiac Output; Cardiomegaly; Carnitine; Heart Rate; Hemodynamics; Male; Myocardial Contraction; Myocardium; Phosphocreatine; Rats; Rats, Inbred WKY; Ventricular Function, Left | 1992 |
Adenosine and carnitine derivatives and calcium movements in rat heart sarcoplasmic reticulum.
Topics: Acetylcarnitine; Adenosine; Animals; Calcium; Carnitine; Heart; In Vitro Techniques; Male; Myocardium; Perfusion; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum | 1992 |
Protection of the ischemic diabetic heart by L-propionylcarnitine therapy.
Topics: Animals; Cardiotonic Agents; Carnitine; Diabetes Mellitus, Experimental; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Rats; Rats, Sprague-Dawley; Streptozocin | 1992 |
Functional and metabolic effects of propionyl-L-carnitine in the isolated perfused hypertrophied rat heart.
Topics: Animals; Blood Pressure; Cardiomegaly; Cardiotonic Agents; Carnitine; Energy Metabolism; Fatty Acids; Heart; Male; Myocardial Contraction; Myocardium; Rats; Rats, Inbred WKY; Stimulation, Chemical; Ventricular Function, Left | 1992 |
L-propionylcarnitine and myocardial performance in stunned porcine myocardium.
Topics: Animals; Cardiotonic Agents; Carnitine; Female; Hemodynamics; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Swine; Vascular Resistance; Ventricular Function, Left | 1992 |
The urinary acylcarnitine profile in three cases of transient hyperammonemia of the newborn.
Topics: Acetylcarnitine; Ammonia; Carnitine; Hippurates; Humans; Infant, Newborn; Male; Time Factors | 1992 |
Prolonged propionyl-L-carnitine pre-treatment of rabbit: biochemical, hemodynamic and electrophysiological effects on myocardium.
Topics: Action Potentials; Animals; Carnitine; Electrophysiology; Heart; Hemodynamics; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Papillary Muscles; Perfusion; Rabbits | 1992 |
Effect of prolonged treatment with propionyl-L-carnitine on erucic acid-induced myocardial dysfunction in rats.
Topics: Adenosine Triphosphate; Animals; Cardiomyopathies; Carnitine; Erucic Acids; Heart; Lipid Metabolism; Male; Mitochondria, Heart; Myocardium; Phosphocreatine; Rats; Rats, Inbred Strains | 1992 |
Free radical scavenging is involved in the protective effect of L-propionyl-carnitine against ischemia-reperfusion injury of the heart.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Carnitine; Creatine Kinase; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Heart; Magnetic Resonance Spectroscopy; Male; Myocardial Reperfusion Injury; Myocardium; Phosphocreatine; Rats; Rats, Inbred Strains | 1991 |
Focus on propionyl-L-carnitine. A symposium. 23-25 October, 1989, Rome, Italy.
Topics: Animals; Carnitine; Humans; Myocardium | 1991 |
New carnitine derivatives for the therapy of cutaneous ulcers in vasculopathics.
Topics: Aged; Aged, 80 and over; Carnitine; Female; Humans; Leg Ulcer; Male; Middle Aged; Skin Ulcer; Vascular Diseases | 1991 |
Protection of the reperfused heart by L-propionylcarnitine.
Topics: Animals; Blood Pressure; Carnitine; Coronary Circulation; Coronary Disease; Female; In Vitro Techniques; L-Lactate Dehydrogenase; Magnetic Resonance Imaging; Mitochondria, Heart; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Phosphocreatine; Phosphorus Isotopes; Rats; Rats, Inbred Strains; Ventricular Function, Left | 1991 |
Effects of propionyl-L-carnitine in chronically hypoperfused ("hibernating") myocardium.
Topics: Animals; Carnitine; Cell Survival; Dobutamine; Myocardial Contraction; Myocardial Reperfusion Injury; Swine; Ventricular Function, Left | 1991 |
Homeostatic equilibrium of L-carnitine family before and after i.v. administration of propionyl-L-carnitine in humans, dogs and rats.
Topics: Acetylcarnitine; Animals; Carnitine; Dogs; Female; Homeostasis; Humans; Injections, Intravenous; Male; Rats; Rats, Inbred Strains; Stereoisomerism | 1991 |
Protein binding of L-carnitine family components.
Topics: Acetylcarnitine; Animals; Blood Proteins; Carnitine; Chromatography, Gel; Dogs; Humans; Palmitoylcarnitine; Protein Binding; Rats; Serum Albumin; Ultrafiltration | 1991 |
Effects of some L-carnitine derivatives on heart membrane ATPases.
Topics: Acetylcarnitine; Animals; Ca(2+) Mg(2+)-ATPase; Calcium-Transporting ATPases; Carnitine; Cell Membrane; Cells, Cultured; Male; Rats; Sarcoplasmic Reticulum; Sodium-Potassium-Exchanging ATPase | 1991 |
Effect of propionyl-L-carnitine on L-type calcium channels in human heart sarcolemma.
Topics: Binding Sites; Calcium; Calcium Channel Blockers; Calcium Channels; Carnitine; Cell Membrane; Culture Techniques; Heart; Humans; Isradipine; Myocardium; Oxadiazoles; Radioligand Assay; Sarcolemma; Tritium | 1991 |
L-propionylcarnitine increases postischemic blood flow but does not affect recovery of energy charge.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium-Binding Proteins; Carnitine; Coronary Circulation; Coronary Disease; Energy Metabolism; Female; Heart; Hemodynamics; Male; Myocardial Reperfusion; Myocardium; Phosphates | 1991 |
Alteration of urinary carnitine profile induced by benzoate administration.
Topics: Acetylcarnitine; Administration, Oral; Amino Acid Metabolism, Inborn Errors; Ammonia; Benzoates; Benzoic Acid; Carnitine; Child, Preschool; Dose-Response Relationship, Drug; Hippurates; Humans; Male | 1991 |
Effect of propionyl carnitine on cardiac energy metabolism evaluated by the release of purine catabolites.
Topics: Adenosine Triphosphate; Animals; Carnitine; Chromatography, High Pressure Liquid; Energy Metabolism; Heart; Heart Rate; In Vitro Techniques; Myocardium; Perfusion; Propionates; Purines; Rats | 1991 |
Antiarrhythmic effect of L-propionylcarnitine in isolated cardiac preparations.
Topics: Animals; Anti-Arrhythmia Agents; Carnitine; Guinea Pigs; Male; Myocardial Reperfusion Injury; Papillary Muscles; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Ventricular Fibrillation | 1991 |
Effect of propionyl carnitine on energy charge and adenine nucleotide content of cardiac endothelial cells during hypoxia.
Topics: Adenine; Animals; Carnitine; Cells, Cultured; Endothelium, Vascular; Energy Metabolism; Hypoxia; Oxidation-Reduction; Oxygen; Rats; Rats, Inbred Strains; Time Factors; Xanthine Oxidase | 1991 |
Protective effect of propionyl carnitine against peroxidative damage to arterial endothelium membranes.
Topics: Animals; Carnitine; Cattle; Cell Membrane; Cell Separation; Dose-Response Relationship, Drug; Endothelium, Vascular; Hydrogen Peroxide; Iron; Reperfusion Injury; Thiobarbiturates; Xanthine Oxidase | 1991 |
Muscle carnitine deficiency in patients with severe peripheral vascular disease.
Topics: Aged; Carnitine; Carnitine O-Acetyltransferase; Carnitine O-Palmitoyltransferase; Humans; Ischemia; Middle Aged; Muscles; Peripheral Vascular Diseases | 1991 |
Rheological activity of propionyl L-carnitine.
Topics: Adenosine Diphosphate; Blood Viscosity; Carnitine; Humans; Pyrrolidines; Vascular Diseases | 1991 |
Effect of carnitine acetyltransferase inhibition on rat hepatocyte metabolism.
Topics: Acetylcarnitine; Animals; Carnitine; Carnitine O-Acetyltransferase; Cell Separation; Liver; Male; Morpholines; Oxidation-Reduction; Propionates; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1991 |
Hemodynamic study of intravenous propionyl-L-carnitine in patients with ischemic heart disease and normal left ventricular function.
Topics: Adult; Carnitine; Coronary Disease; Female; Hemodynamics; Humans; Injections, Intravenous; Male; Middle Aged; Pulmonary Circulation | 1991 |
Effect of propionyl-L-carnitine on mechanical function of isolated rabbit heart.
Topics: Acetylcarnitine; Animals; Carnitine; Electric Stimulation; Heart; Injections, Intraperitoneal; Male; Myocardial Contraction; Rabbits | 1991 |
Short-term hemodynamic effects of intravenous propionyl-L-carnitine in anesthetized dogs.
Topics: Animals; Carnitine; Coronary Circulation; Dogs; Female; Hemodynamics; Infusions, Intravenous; Injections, Intravenous; Kidney; Male | 1991 |
The effect of propionyl-L-carnitine on the ischemic and reperfused intact myocardium and on their derived mitochondria.
Topics: Adenosine Triphosphate; Animals; Carnitine; Coronary Disease; Heart; Mitochondria, Heart; Myocardial Reperfusion Injury; Rabbits | 1991 |
Delineation of the influence of propionylcarnitine on the accumulation of long-chain acylcarnitines and electrophysiologic derangements evoked by hypoxia in canine myocardium.
Topics: Animals; Carnitine; Coronary Disease; Dogs; Electrophysiology; Heart; Hypoxia; Membrane Potentials; Myocardium | 1991 |
Biochemical profile of propionyl-L-carnitine.
Topics: Acyl Coenzyme A; Animals; Carnitine; Cell Membrane; Humans; Myocardium; Propionates; Rats | 1991 |
Protective effects of propionyl-L-carnitine during ischemia and reperfusion.
Topics: Acetylcarnitine; Acyl Coenzyme A; Animals; Carnitine; Coronary Disease; Hemodynamics; Male; Myocardial Reperfusion; Rats; Rats, Inbred Strains | 1991 |
Effect of propionyl-L-carnitine on experimental myocardial infarction in dogs.
Topics: Animals; Calcium Channel Blockers; Carnitine; Creatine Kinase; Dogs; Drug Evaluation, Preclinical; Female; Hemodynamics; L-Lactate Dehydrogenase; Male; Myocardial Infarction; Propylamines; Tiapamil Hydrochloride | 1991 |
Effect of propionyl-L-carnitine on human endothelial cells.
Topics: Acetylcarnitine; Calcium; Carnitine; Cells, Cultured; Endothelium, Vascular; Humans; Lipoproteins, LDL | 1991 |
Lack of correlation between the antiarrhythmic effect of L-propionylcarnitine on reoxygenation-induced arrhythmias and its electrophysiological properties.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Barium; Carnitine; Coronary Circulation; Creatine Kinase; Digoxin; Electrocardiography; Electrophysiology; Guinea Pigs; In Vitro Techniques; L-Lactate Dehydrogenase; Membrane Potentials; Perfusion; Purkinje Fibers; Sheep; Strophanthidin | 1991 |
Electrophysiologic evaluation of intravenous L-propionylcarnitine in man.
Topics: Blood Pressure; Carnitine; Catheterization, Peripheral; Electrophysiology; Female; Heart Atria; Heart Conduction System; Heart Ventricles; Humans; Injections, Intravenous; Male; Middle Aged; Refractory Period, Electrophysiological; Sinoatrial Node; Time Factors | 1991 |
L-carnitine and carnitine ester transport in the rat small intestine.
Topics: Acetylcarnitine; Animals; Carnitine; Ether; Intestinal Absorption; Jejunum; Male; Potassium; Rats; Rats, Inbred Strains | 1991 |
Protective action of propionyl-L-carnitine on toxicity induced by hyperbaric oxygen.
Topics: Animals; Carnitine; Hyperbaric Oxygenation; Lung Diseases; Male; Mice; Seizures | 1990 |
Effects of administration of L-propionylcarnitine during ischemia on the recovery of myocardial function in the anesthetised pig.
Topics: Adenosine Triphosphate; Animals; Carnitine; Coronary Circulation; Myocardial Contraction; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Phosphocreatine; Sarcoplasmic Reticulum; Swine; Time Factors; Ventricular Function, Left | 1990 |
Na(+)-H+ exchange in cardiac sarcolemmal vesicles isolated from diabetic rats.
Topics: Amiloride; Animals; Calcium; Carnitine; Carrier Proteins; Diabetes Mellitus, Experimental; Hydrogen; Hydrogen-Ion Concentration; Male; Myocardium; Rats; Rats, Inbred Strains; Sarcolemma; Sodium; Sodium-Hydrogen Exchangers; Streptozocin | 1990 |
The effect of acute feeding of carnitine, acetyl carnitine and propionyl carnitine on basal and A23187-stimulated eicosanoid release from rat carrageenan-elicited peritoneal macrophages.
Topics: 6-Ketoprostaglandin F1 alpha; Acetylcarnitine; Animals; Calcimycin; Carnitine; Dinoprostone; Eicosanoic Acids; Leukotriene B4; Macrophages; Male; Rats; Rats, Inbred Strains; Thromboxane B2 | 1990 |
Metabolic effects induced by L-carnitine and propionyl-L-carnitine in human hypoxic muscle tissue during exercise.
Topics: Carnitine; Humans; Hypoxia; Lipid Peroxides; Muscles; Physical Exertion; Time Factors | 1990 |
Effect of propionyl-L-carnitine on rat spinal cord ischaemia and post-ischaemic reperfusion injury.
Topics: Animals; Carnitine; Free Radicals; In Vitro Techniques; Ischemia; Lipid Peroxidation; Male; Rats; Rats, Inbred Strains; Reperfusion Injury; Spinal Cord; Thiobarbiturates | 1990 |
Carnitine deficiency in inherited organic acid disorders and Reye syndrome.
Topics: Amino Acid Metabolism, Inborn Errors; Carnitine; Child, Preschool; Humans; Infant; Male; Metabolism, Inborn Errors; Methylmalonic Acid; Mitochondria; Propionates; Reye Syndrome | 1990 |
Electrophysiologic effects of a short-chain acyl carnitine, L-propionylcarnitine, on isolated canine Purkinje fibers.
Topics: Action Potentials; Animals; Carnitine; Dogs; Female; Heart Conduction System; In Vitro Techniques; Male; Potassium; Purkinje Fibers | 1989 |
Effect of carnitine on propionate metabolism in the vitamin B-12--deficient rat.
Topics: Animals; Carnitine; Glucose; Liver; Male; Propionates; Pyruvates; Rats; Rats, Inbred F344; Vitamin B 12 Deficiency | 1989 |
Direct identification of propionylcarnitine in propionic acidaemia: biochemical and clinical results of oral carnitine supplementation.
Topics: Amino Acid Metabolism, Inborn Errors; Carnitine; Chromatography, Paper; Humans; Infant, Newborn; Male; Mass Spectrometry; Muscle Hypotonia; Propionates | 1986 |
Interactions of propionate and carnitine metabolism in isolated rat hepatocytes.
Topics: Acetylcarnitine; Animals; Carbon Dioxide; Carnitine; Glucose; In Vitro Techniques; Liver; Male; Propionates; Rats; Rats, Inbred Strains | 1987 |
Amniotic fluid propionylcarnitine in methylmalonic aciduria.
Topics: Acetylcarnitine; Amino Acid Metabolism, Inborn Errors; Amniotic Fluid; Carnitine; Chromatography, High Pressure Liquid; Female; Humans; Malonates; Methylmalonic Acid | 1987 |
Propionate metabolism in the rat heart by 13C n.m.r. spectroscopy.
Topics: Animals; Carbon Isotopes; Carnitine; In Vitro Techniques; Magnetic Resonance Spectroscopy; Methylmalonic Acid; Myocardium; Perfusion; Propionates; Pyruvates; Pyruvic Acid; Rats | 1988 |
Carnitine metabolism in the vitamin B-12-deficient rat.
Topics: Acetylcarnitine; Animals; Body Weight; Carnitine; Fasting; Male; Methylmalonic Acid; Rats; Vitamin B 12 Deficiency | 1988 |
Application of high-performance liquid chromatography to the analysis of propionyl-L-carnitine by a stereospecific enzyme assay.
Topics: Animals; Carnitine; Chromatography, High Pressure Liquid; Dogs; Humans; Hydrolysis; Rats; Spectrophotometry, Ultraviolet; Stereoisomerism | 1988 |
Prevention by propionylcarnitine of NADPH and tert-butyl hydroperoxide-dependent chemiluminescence in heart microsomes.
Topics: Animals; Carnitine; Free Radicals; Kinetics; Luminescent Measurements; Microsomes; Myocardium; NADP; Oxidation-Reduction; Peroxides; Rats; tert-Butylhydroperoxide | 1988 |
Effects of L-propionylcarnitine on electrical and mechanical alterations induced by amphiphilic lipids in isolated guinea pig ventricular muscle.
Topics: Animals; Carnitine; Electrophysiology; Female; Guinea Pigs; Lysophosphatidylcholines; Male; Microscopy, Electron; Myocardial Contraction; Myocardium; Palmitoylcarnitine; Papillary Muscles | 1988 |
The effects of propionylcarnitine taurine on cardiac performance in aerobic and ischemic myocardium.
Topics: Animals; Carnitine; Coronary Disease; Heart; Oxygen; Perfusion; Swine; Taurine | 1988 |
Differences between carnitine derivatives and coenzyme Q10 in preventing in vitro doxorubicin-related cardiac damages.
Topics: Animals; Carnitine; Doxorubicin; Heart; Male; Muscle Proteins; Myocardium; Oxygen; Rats; Rats, Inbred Strains; Ubiquinone | 1988 |
Effects of L-propionylcarnitine on mechanical recovery during reflow in intact hearts.
Topics: Animals; Carnitine; Coenzyme A; Coronary Circulation; Fatty Acids; Heart; Myocardial Contraction; Oxygen Consumption; Swine | 1988 |
Differential effects of L-propionylcarnitine on the electrical and mechanical properties of guinea pig ventricular muscle in normal and acidic conditions.
Topics: Action Potentials; Animals; Carnitine; Guinea Pigs; Hydrogen-Ion Concentration; Myocardial Contraction; Palmitoylcarnitine; Papillary Muscles | 1987 |
Analytical method for urinary glutarylcarnitine, acetylcarnitine and propionylcarnitine with a carboxylic acid analyser and a reversed-phase column.
Topics: Acetylcarnitine; Adolescent; Carboxylic Acids; Carnitine; Child, Preschool; Chromatography, High Pressure Liquid; Female; Humans; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry | 1987 |
Characteristics of the transport of carnitine into the cauda epididymidis of the rat as ascertained by luminal perfusion in vitro.
Topics: Animals; Betaine; Biological Transport, Active; Carnitine; Chromatography, Thin Layer; Epididymis; In Vitro Techniques; Inulin; Kinetics; Male; Perfusion; Rats; Rats, Inbred Strains; Stereoisomerism | 1986 |
Metabolism and excretion of carnitine and acylcarnitines in the perfused rat kidney.
Topics: Absorption; Acetylcarnitine; Albumins; Animals; Carnitine; Kidney; Male; Metabolic Clearance Rate; Perfusion; Rats; Rats, Inbred Strains | 1986 |
Protection of the ischaemic myocardium by L-propionylcarnitine: effects on the recovery of cardiac output after ischaemia and reperfusion, carnitine transport, and fatty acid oxidation.
Topics: Acetylcarnitine; Adenosine Triphosphate; Animals; Blood Pressure; Cardiac Output; Carnitine; Coronary Disease; Fatty Acids; Male; Myocardial Contraction; Myocardium; Oxidation-Reduction; Palmitic Acid; Palmitic Acids; Phosphocreatine; Rats; Rats, Inbred Strains | 1986 |
Inhibition of oxidative metabolism by propionic acid and its reversal by carnitine in isolated rat hepatocytes.
Topics: Animals; Carnitine; Drug Interactions; In Vitro Techniques; Liver; Male; Mass Spectrometry; Oxidation-Reduction; Palmitic Acid; Palmitic Acids; Propionates; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Starvation | 1986 |
Pitfalls in the assay of acylcarnitine.
Topics: Acetylcarnitine; Carnitine; Humans; Hydrogen-Ion Concentration; Hydrolysis; Radiochemistry | 1986 |
Biochemical evidence of carnitine effect on propionate elimination.
Topics: Carboxy-Lyases; Carnitine; Fibroblasts; Humans; Infant; Methylmalonyl-CoA Decarboxylase; Propionates; Skin | 1984 |
Urinary excretion of l-carnitine and acylcarnitines by patients with disorders of organic acid metabolism: evidence for secondary insufficiency of l-carnitine.
Topics: Acyl-CoA Dehydrogenases; Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids, Branched-Chain; Carnitine; Child; Child, Preschool; Female; Hemiterpenes; Humans; Infant; Infant, Newborn; Lysine; Male; Methylmalonic Acid; Middle Aged; Pentanoic Acids; Propionates | 1984 |
Thermospray liquid chromatography/mass spectrometry for the analysis of L-carnitine and its short-chain acyl derivatives.
Topics: Acetylcarnitine; Carnitine; Chromatography, High Pressure Liquid; Hot Temperature; Mass Spectrometry | 1984 |
The effect of intravenous L-carnitine on propionic acid excretion in acute propionic acidaemia.
Topics: Amino Acid Metabolism, Inborn Errors; Carnitine; Female; Humans; Infant; Injections, Intravenous; Propionates | 1984 |
Metabolic response to carnitine in methylmalonic aciduria. An effective strategy for elimination of propionyl groups.
Topics: Acetylcarnitine; Amino Acid Metabolism, Inborn Errors; Carnitine; Female; Humans; Infant; Malonates; Methylmalonic Acid | 1983 |
Propionylcarnitine excretion in propionic and methylmalonic acidurias: a cause of carnitine deficiency.
Topics: Carnitine; Child, Preschool; Humans; Infant; Infant, Newborn; Malonates; Metabolism, Inborn Errors; Methylmalonic Acid; Muscles; Propionates | 1984 |
L-carnitine enhances excretion of propionyl coenzyme A as propionylcarnitine in propionic acidemia.
Topics: Acyl Coenzyme A; Adolescent; Carboxy-Lyases; Carnitine; Child; Child, Preschool; Humans; Infant; Male; Mass Spectrometry; Metabolism, Inborn Errors; Methylmalonyl-CoA Decarboxylase; Propionates | 1984 |
Pyruvate carboxylase and propionyl-CoA carboxylase as anaplerotic enzymes in skeletal muscle mitochondria.
Topics: Acetylcarnitine; Adenosine Triphosphate; Animals; Bicarbonates; Carbon Dioxide; Carbon-Carbon Ligases; Carnitine; Citric Acid Cycle; Ligases; Mitochondria, Heart; Mitochondria, Muscle; Pyruvate Carboxylase; Pyruvates; Rats | 1980 |
Reversal of ischemia-induced mitochondrial dysfunction after coronary reperfusion.
Topics: Acyl Coenzyme A; Adenosine Diphosphate; Animals; Carnitine; Coronary Circulation; Coronary Disease; Dogs; Female; Lipids; Male; Mitochondria, Heart; Oxygen Consumption; Perfusion | 1982 |
Mechanism of free fatty acid-induced arrhythmias.
Topics: Acetylcarnitine; Acyl Coenzyme A; Animals; Arrhythmias, Cardiac; Calcium; Carnitine; Dogs; Fatty Acids, Nonesterified; Heart; Mitochondria, Heart | 1982 |
Effect of L-propionyl carnitine on some properties of erythrocytes and leukocytes of alcohol abusers.
Topics: Alcoholism; Blood Donors; Carnitine; Case-Control Studies; Chemotaxis, Leukocyte; Cytochrome c Group; Erythrocyte Membrane; Humans; Male; Oxidation-Reduction; Sodium-Potassium-Exchanging ATPase; Superoxides | 1995 |
L-propionylcarnitine does not affect myocardial metabolic or functional response to chronotropic and inotropic stimulation after repetitive ischemia in anesthetized pigs.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Pressure; Cardiotonic Agents; Carnitine; Coronary Circulation; Dobutamine; Female; Heart; Heart Rate; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Swine; Vascular Resistance | 1993 |
Propionyl L-carnitine improvement of hypertrophied heart function is accompanied by an increase in carbohydrate oxidation.
Topics: Animals; Carbohydrate Metabolism; Cardiomegaly; Cardiotonic Agents; Carnitine; Male; Oxidation-Reduction; Rats; Rats, Inbred WKY | 1995 |
Propionyl-L-carnitine prevents the progression of atherosclerotic lesions in aged hyperlipemic rabbits.
Topics: Aging; Animals; Arteriosclerosis; Carnitine; Cell Division; Diet; Disease Models, Animal; Female; Foam Cells; Hyperlipidemias; Immunohistochemistry; Lipoproteins, VLDL; Male; Muscle, Smooth, Vascular; Rabbits | 1995 |
Short term effects of intra-arterial propionyl-L-carnitine on isolated canine hind-limbs.
Topics: Animals; Blood Circulation; Blood Vessels; Carnitine; Dogs; Female; Hemodynamics; Hindlimb; In Vitro Techniques; Infusions, Intra-Arterial; Male; Muscle, Skeletal; Perfusion | 1995 |
Carnitine palmitoyl transferase-I activity in the aging mouse heart.
Topics: Aging; Animals; Cardiotonic Agents; Carnitine; Carnitine O-Palmitoyltransferase; Male; Mice; Mice, Inbred C57BL; Mitochondria, Heart; Myocardial Reperfusion Injury; Myocardium | 1995 |
Effects of acetyl- and proprionyl-L-carnitine on peripheral nerve function and vascular supply in experimental diabetes.
Topics: Acetylcarnitine; Action Potentials; Animals; Blood Flow Velocity; Blood Glucose; Body Weight; Carnitine; Diabetes Mellitus, Experimental; Kinetics; Male; Neural Conduction; Peripheral Nerves; Rats; Rats, Sprague-Dawley; Sciatic Nerve | 1995 |
L-propionylcarnitine effects on cardiac carnitine content and function in secondary carnitine deficiency.
Topics: Animals; Aorta; Blood Pressure; Cardiotonic Agents; Carnitine; Heart; Heart Rate; In Vitro Techniques; Male; Myocardium; Pentanoic Acids; Perfusion; Rats; Rats, Sprague-Dawley | 1995 |
Myocyte performance during evolution of myocardial infarction in rats: effects of propionyl-L-carnitine.
Topics: Animals; Calcium; Cardiotonic Agents; Carnitine; Cytosol; Electric Stimulation; Heart; Male; Myocardial Infarction; Myocardium; Rats; Rats, Sprague-Dawley | 1995 |
Effect of propionyl-L-carnitine (PLC) on the kinetic properties of the myofibrillar system in pressure overload cardiac hypertrophy.
Topics: Animals; Cardiomegaly; Cardiotonic Agents; Carnitine; Heart; Heart Ventricles; Kinetics; Male; Myocardial Contraction; Myofibrils; Organ Size; Rats; Rats, Inbred WKY; Reference Values | 1995 |
Propionyl-L-carnitine improves mechanical performance of papillary muscle from dilated cardiomyopathic hamsters.
Topics: Animals; Cardiomyopathy, Dilated; Cardiotonic Agents; Carnitine; Cricetinae; Myocardial Contraction; Papillary Muscles | 1995 |
Protective effect of propionyl-L-carnitine against PAF-induced rat paw oedema.
Topics: Animals; Cardiotonic Agents; Carnitine; Carrageenan; Dose-Response Relationship, Drug; Edema; Indomethacin; Male; Phenylbutazone; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Time Factors | 1995 |
Production of acyl-carnitines from the metabolism of [U-14C]3-methyl-2-oxopentanoate by rat liver and skeletal muscle mitochondria.
Topics: Acetylcarnitine; Amino Acids, Branched-Chain; Animals; Carnitine; Chromatography, High Pressure Liquid; Keto Acids; Kinetics; Male; Mitochondria, Liver; Mitochondria, Muscle; Oxidation-Reduction; Rats; Rats, Wistar | 1995 |
Effect of L-propionyl carnitine on in-vitro membrane alteration of sickle-cell anaemia erythrocytes.
Topics: Anemia, Sickle Cell; Cardiotonic Agents; Carnitine; Erythrocyte Membrane; Filtration; Free Radicals; Humans; In Vitro Techniques; Lipid Peroxidation | 1994 |
Effects of short- and long-term feeding of L-carnitine and congeners on the production of eicosanoids from rat peritoneal leucocytes.
Topics: 6-Ketoprostaglandin F1 alpha; Acetylcarnitine; Animals; Carnitine; Cell Count; Eicosanoids; In Vitro Techniques; Leukotriene B4; Macrophages, Peritoneal; Male; Rats; Rats, Wistar; Time Factors | 1994 |
Urinary propionylcarnitine analysis for monitoring carnitine supplementation in inherited disorders of propionate metabolism.
Topics: Adolescent; Carnitine; Child; Child, Preschool; Female; Humans; Infant; Male; Metabolism, Inborn Errors; Propionates | 1994 |
Propionyl-L-carnitine-mediated improvement in contractile function of rat hearts oxidizing acetoacetate.
Topics: Acetoacetates; Animals; Cardiotonic Agents; Carnitine; Citric Acid Cycle; Coenzyme A; Glucose; Heart; Male; Models, Biological; Myocardial Contraction; Myocardium; Oxidation-Reduction; Rats; Rats, Sprague-Dawley | 1995 |
Protection of beta-thalassaemic erythrocytes from oxidative stress by propionyl carnitine.
Topics: Adult; beta-Thalassemia; Carnitine; Erythrocytes; Female; Humans; Male; Middle Aged; Oxidative Stress | 1994 |
L-propionyl carnitine protects erythrocytes and low density lipoproteins against peroxidation.
Topics: Animals; Antioxidants; Carnitine; Copper; Erythrocytes; Lipid Peroxidation; Lipoproteins, LDL; Male; Methionine; Rats; Rats, Sprague-Dawley | 1994 |
The potentiating effect of propionyl carnitine on prostacycline prevention of thrombosis induced by endothelin (ET-1) and K-carrageenin.
Topics: Animals; Cardiotonic Agents; Carnitine; Carrageenan; Drug Synergism; Endothelins; Epoprostenol; Male; Necrosis; Rats; Rats, Wistar; Tail; Thrombosis | 1994 |
[The Italian contribution to the application of high-technology methods to clinical trials].
Topics: Cardiology; Carnitine; Clinical Trials as Topic; Computer Communication Networks; Echocardiography; Heart Failure; Humans; Italy; Medical Laboratory Science; Myocardial Infarction; Software | 1993 |
Propionyl-L-carnitine prevents myocardial mechanical alterations due to pressure overload in rats.
Topics: Animals; Aorta; Cardiomegaly; Cardiotonic Agents; Carnitine; Constriction, Pathologic; Heart; Heart Ventricles; Hypertension; Male; Myocardial Contraction; Myocardium; Myosins; Papillary Muscles; Rats; Rats, Inbred WKY | 1994 |
Contrasting effects of propionate and propionyl-L-carnitine on energy-linked processes in ischemic hearts.
Topics: Animals; Cardiotonic Agents; Carnitine; Coenzyme A; Energy Metabolism; Esters; In Vitro Techniques; Male; Mitochondria, Heart; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Propionates; Rats; Rats, Wistar | 1994 |
Metabolic effects of propionate, hexanoate and propionylcarnitine in normoxia, ischaemia and reperfusion. Does an anaplerotic substrate protect the ischaemic myocardium?
Topics: Animals; Caproates; Cardiotonic Agents; Carnitine; Energy Metabolism; Heart; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Oxygen Consumption; Propionates; Rats; Rats, Sprague-Dawley; Tricarboxylic Acids | 1994 |
Effect of the addition of electrolytes on the partition coefficients, activity coefficients, and acid dissociation constants of carnitine and its acetyl and propionyl derivatives.
Topics: 1-Octanol; Acetylcarnitine; Biological Transport; Carnitine; Cations; Chemical Phenomena; Chemistry, Physical; Electrolytes; Kinetics; Metals; Octanols; Osmolar Concentration; Solubility; Thermodynamics; Water | 1994 |
Anaplerotic effect of propionyl carnitine in rat heart mitochondria.
Topics: Acetylcarnitine; Animals; Carbon Dioxide; Cardiotonic Agents; Carnitine; Male; Malonates; Mitochondria, Heart; Mitochondria, Liver; Oxygen Consumption; Pyruvates; Rats; Rats, Wistar | 1994 |
Free carnitine and short-chain acylcarnitines in cerebrospinal fluid of patients with disorders of propionate metabolism determined by fast atom bombardment and tandem mass spectrometry.
Topics: Adolescent; Carnitine; Female; Humans; Infant; Mass Spectrometry; Metabolic Diseases; Propionates; Spectrometry, Mass, Fast Atom Bombardment | 1994 |
Inhibitory effects of propionyl-L-carnitine on plasma extravasation induced by irritants in rodents.
Topics: Acetylcarnitine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capillary Permeability; Carnitine; Carrageenan; Dermatitis; Edema; Exudates and Transudates; Gossypium; Granuloma; Irritants; Male; Mice; Peritonitis; Rats; Rats, Sprague-Dawley | 1993 |
Quantification of free carnitine, individual short- and medium-chain acylcarnitines, and total carnitine in plasma by high-performance liquid chromatography.
Topics: Acetylcarnitine; Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenases; Acylation; Carnitine; Chromatography, High Pressure Liquid; Humans; Methylmalonic Acid; Molecular Weight; Propionates; Reference Standards; Reproducibility of Results | 1993 |
Protective role of propionyl carnitine in vascular disorders experimentally induced by endothelin (ET-1) serotonin and K-carrageenin.
Topics: Animals; Cardiovascular Agents; Carnitine; Carrageenan; Endothelins; Male; Rats; Rats, Wistar; Regional Blood Flow; Serotonin; Tail; Thrombosis; Vascular Diseases | 1993 |
Thrombosis induced by endothelin (ET-1) and carrageenin in rats treated with indomethacin and propionyl carnitine.
Topics: Animals; Cardiotonic Agents; Carnitine; Carrageenan; Eicosanoids; Endothelins; Indomethacin; Male; Rats; Rats, Wistar; Thrombosis | 1993 |
Control of the cardiac consequences of myocardial ischemia and reperfusion by L-propionylcarnitine: age-response and dose-response studies in the rat heart.
Topics: Aging; Animals; Animals, Newborn; Cardiotonic Agents; Carnitine; Coronary Circulation; Dose-Response Relationship, Drug; Female; Heart; Heart Rate; Male; Myocardial Ischemia; Myocardial Reperfusion; Pregnancy; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 1993 |
Carnitine delays rat skeletal muscle fatigue in vitro.
Topics: Animals; Carnitine; Electric Stimulation; Glycogen; In Vitro Techniques; Kinetics; Lactates; Lactic Acid; Male; Muscle Contraction; Muscle Relaxation; Muscles; Rats; Rats, Sprague-Dawley | 1993 |
L-propionylcarnitine and synchronization of spontaneous activity in rat isolated portal vein.
Topics: Animals; Cardiotonic Agents; Carnitine; Electrophysiology; Extracellular Space; In Vitro Techniques; Isometric Contraction; Male; Muscle Contraction; Muscle, Smooth, Vascular; Osmolar Concentration; Portal Vein; Rats; Rats, Wistar | 1993 |
Effect of propionyl-L-carnitine in a rat model of peripheral arteriopathy: a functional, histologic, and NMR spectroscopic study.
Topics: Animals; Cardiotonic Agents; Carnitine; Disease Models, Animal; Energy Metabolism; Femoral Artery; Hindlimb; Magnetic Resonance Spectroscopy; Male; Muscles; Peripheral Vascular Diseases; Rats; Rats, Wistar | 1993 |
Assessment of the cardiostimulant action of propionyl-L-carnitine on chronically volume-overloaded rat hearts.
Topics: Animals; Carbon Dioxide; Cardiomegaly; Cardiotonic Agents; Carnitine; Mitochondria, Heart; Myocardial Contraction; Myocardium; Oxygen Consumption; Palmitates; Rats; Rats, Wistar; Ventricular Function, Left | 1993 |
Effects of L-carnitine and its acetate and propionate esters on the molecular dynamics of human erythrocyte membrane.
Topics: Acetylcarnitine; Carnitine; Diphenylhexatriene; Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Esters; Humans; Membrane Fluidity; Membrane Proteins; Palmitoylcarnitine; Pyrimidinones; Spin Labels | 1993 |
Acylcarnitines in amniotic fluid: application to the prenatal diagnosis of propionic acidaemia.
Topics: Acylation; Amino Acid Metabolism, Inborn Errors; Amniotic Fluid; Carnitine; Female; Gestational Age; Humans; Mass Spectrometry; Pregnancy; Prenatal Diagnosis; Propionates; Reference Values | 1993 |
Propionyl-L-carnitine limits chronic ventricular dilation after myocardial infarction in rats.
Topics: Administration, Oral; Animals; Blood Pressure; Carnitine; Enalapril; Hypertrophy, Left Ventricular; Male; Myocardial Infarction; Myocardium; Rats; Ventricular Function, Left | 1993 |
Propionyl-L-carnitine: labelling in the N-methyl position with carbon-11 and pharmacokinetic studies in rats.
Topics: Animals; Biotransformation; Carbon Radioisotopes; Cardiotonic Agents; Carnitine; Cyclotrons; Isotope Labeling; Liver; Male; Metabolic Clearance Rate; Models, Biological; Myocardium; Rats; Rats, Sprague-Dawley; Time Factors; Tissue Distribution | 1995 |
Effect of propionyl-L-carnitine on motor nerve conduction, autonomic cardiac function, and nerve blood flow in rats with streptozotocin-induced diabetes: comparison with an aldose reductase inhibitor.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Body Weight; Carbohydrate Metabolism; Cardiotonic Agents; Carnitine; Cauda Equina; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Electrocardiography; Enzyme Inhibitors; Heart Conduction System; Lipids; Male; Motor Neurons; Neural Conduction; Rats; Rats, Wistar; Sciatic Nerve; Tetrazoles; Thiophenes | 1996 |
Alterations in energy metabolism of hypertrophied rat cardiomyocytes: influence of propionyl-L-carnitine.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cardiomegaly; Cardiotonic Agents; Carnitine; Cell Size; Disease Models, Animal; Energy Metabolism; Fatty Acids; Glucose; Heart; Heart Ventricles; In Vitro Techniques; Male; Myocardium; Oxidation-Reduction; Palmitates; Phosphocreatine; Rats; Rats, Inbred WKY | 1995 |
Effects of propionyl-L-carnitine and insulin on the electroretinogram, nerve conduction and nerve blood flow in rats with streptozotocin-induced diabetes.
Topics: Animals; Blood Glucose; Body Weight; Cardiotonic Agents; Carnitine; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Electroretinography; Hypoglycemic Agents; Insulin; Lipids; Male; Neural Conduction; Polymers; Rats; Rats, Wistar; Regional Blood Flow; Retina; Retinal Vessels; Sciatic Nerve; Sorbitol | 1996 |
Effect of propionyl-l-carnitine and enalapril on cardiac function of pressure-overloaded rats during increase in load.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiotonic Agents; Carnitine; Enalapril; Heart; Hemodynamics; Male; Rats; Rats, Inbred WKY | 1995 |
Propionyl L-carnitine improvement of hypertrophied rat heart function is associated with an increase in cardiac efficiency.
Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Adenosine Triphosphate; Animals; Cardiomegaly; Cardiotonic Agents; Carnitine; Heart; In Vitro Techniques; Male; Malonyl Coenzyme A; Myocardium; Rats; Rats, Inbred WKY | 1995 |
Effect of propionyl-L-carnitine treatment on membrane phospholipid fatty acid turnover in diabetic rat erythrocytes.
Topics: Administration, Oral; Animals; Cardiotonic Agents; Carnitine; Diabetes Mellitus, Experimental; Erythrocyte Membrane; Fatty Acids; Male; Phospholipids; Rats; Rats, Sprague-Dawley | 1995 |
Uptake of [N-methyl-11C]propionyl-L-carnitine (PLC) in human myocardium.
Topics: Adult; Carbon Radioisotopes; Cardiotonic Agents; Carnitine; Coronary Circulation; Female; Humans; Male; Middle Aged; Myocardium | 1996 |
Effect of propionyl-L-carnitine on the mechanics of right and left papillary muscles from volume-overloaded rat hearts.
Topics: Anastomosis, Surgical; Animals; Aorta, Abdominal; Cardiomegaly; Cardiotonic Agents; Carnitine; Male; Papillary Muscles; Rats; Rats, Wistar; Venae Cavae | 1996 |
Effect of long-term treatment with propionyl-L-carnitine on smooth muscle cell polyploidy in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Body Weight; Cardiotonic Agents; Carnitine; Dose-Response Relationship, Drug; Flow Cytometry; Male; Muscle, Smooth, Vascular; Organ Size; Polyploidy; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Species Specificity | 1996 |
L-propionylcarnitine enhancement of substrate oxidation and mitochondrial respiration in the diabetic rat heart.
Topics: Analysis of Variance; Animals; Biomechanical Phenomena; Cardiotonic Agents; Carnitine; Citric Acid Cycle; Diabetes Mellitus, Experimental; Heart; Male; Mitochondria, Heart; Myocardium; Oxidation-Reduction; Oxygen Consumption; Rats; Rats, Sprague-Dawley | 1996 |
Control of oxidative metabolism in volume-overloaded rat hearts: effect of pretreatment with propionyl-L-carnitine.
Topics: Acetyl Coenzyme A; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Carnitine; Cytosol; Energy Metabolism; Glycolysis; Heart; Myocardium; NAD; Oxidative Phosphorylation; Oxygen Consumption; Rats; Rats, Wistar | 1996 |
Effect of propionyl-L-carnitine on oscillatory potentials in electroretinogram in streptozotocin-diabetic rats.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Body Weight; Carnitine; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Electroretinography; Fructose; Inositol; Insulin; Lipids; Male; Rats; Rats, Wistar; Retina; Sorbitol; Streptozocin | 1996 |
Protective effect of L-propionylcarnitine on cyclosporine-induced nephrotoxicity.
Topics: Analysis of Variance; Animals; Carnitine; Cyclosporine; Dose-Response Relationship, Drug; Kidney Diseases; Male; Rats; Rats, Wistar | 1995 |
Cyclosporine nephrotoxicity evaluated by tissue calcium deposition and tubular enzymes is prevented by L-propionylcarnitine in isolated perfused rat kidney.
Topics: Acetylglucosaminidase; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium; Carnitine; Cyclosporine; Dose-Response Relationship, Drug; Immunosuppressive Agents; In Vitro Techniques; Kidney; Kidney Tubules; Male; Perfusion; Rats; Rats, Wistar | 1996 |
Determination of L-carnitine, acetyl-L-carnitine and propionyl-L-carnitine in human plasma by high-performance liquid chromatography after pre-column derivatization with 1-aminoanthracene.
Topics: Acetylcarnitine; Anthracenes; Carnitine; Chromatography, High Pressure Liquid; Fluorescent Dyes; Humans; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence | 1996 |
Positive action of propionyl-L-carnitine on mechanical performance of papillary muscle from Syrian hamsters with hereditary dilated cardiomyopathy.
Topics: Administration, Oral; Analysis of Variance; Animals; Biomechanical Phenomena; Cardiomyopathy, Dilated; Cardiotonic Agents; Carnitine; Cricetinae; Disease Models, Animal; Genetic Diseases, Inborn; Male; Mesocricetus; Myocardial Contraction; Papillary Muscles | 1995 |
[Rationale for metabolic treatment of left ventricular dysfunction].
Topics: Adenosine Triphosphate; Animals; Cardiotonic Agents; Carnitine; Humans; Myocardium; Phosphocreatine; Ventricular Dysfunction, Left | 1995 |
[Metabolism and function of peripheral muscles in heart failure: pharmacologic effects].
Topics: Cardiotonic Agents; Carnitine; Exercise; Heart Failure; Humans; Muscle, Skeletal; Regional Blood Flow | 1995 |
Control of oxidative metabolism in volume-overloaded rat hearts: effect of propionyl-L-carnitine.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Pressure; Body Weight; Cardiomegaly; Cardiotonic Agents; Carnitine; Coronary Circulation; Energy Metabolism; Glucose; Glycolysis; Heart; Heart Rate; Hemodynamics; In Vitro Techniques; Insulin; Mitochondria, Heart; Myocardium; Organ Size; Oxygen Consumption; Palmitic Acid; Rats; Rats, Wistar; Ventricular Function, Left | 1997 |
The effect of propionyl L-carnitine on skeletal muscle metabolism in renal failure.
Topics: Adenosine Triphosphate; Anemia; Carnitine; Exercise; Female; Hemoglobins; Humans; Kidney Failure, Chronic; Magnetic Resonance Spectroscopy; Male; Middle Aged; Mitochondria, Muscle; Muscle, Skeletal; Oxygen Consumption; Peritoneal Dialysis, Continuous Ambulatory; Phosphocreatine; Renal Dialysis | 1997 |
Automated chemoenzymatic synthesis of no-carrier-added [carbonyl-11C]propionyl L-carnitine for pharmacokinetic studies.
Topics: Acetate Kinase; Automation; Carbon Dioxide; Carbon Radioisotopes; Carnitine; Carnitine O-Acetyltransferase; Cyclotrons; Humans; Indicators and Reagents; Isotope Labeling; Phosphate Acetyltransferase; Radiation Protection; Tomography, Emission-Computed | 1997 |
L-propionyl carnitine, an endogenous ester in fatty acid metabolism, exerts anti-shock and endothelial protective effects in rat splanchnic ischemia-reperfusion injury.
Topics: Animals; Blood Pressure; Carnitine; Endothelium, Vascular; Fatty Acids; Intestines; Male; Mesenteric Arteries; Mesenteric Vascular Occlusion; Neutrophils; Peroxidase; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Shock; Splanchnic Circulation; Survival Rate; Time Factors | 1998 |
Carnitines increase plasma levels of adenosine and ATP in humans.
Topics: Acetylcarnitine; Adenosine; Adenosine Triphosphate; Aged; Analysis of Variance; Cardiotonic Agents; Carnitine; Female; Humans; Infusions, Intravenous; Inosine; Intermittent Claudication; Male | 1997 |
Acute CYA-induced ATP depletion is prevented by pretreatment with L-propionylcarnitine in isolated and perfused rat kidney.
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carnitine; Cyclosporine; In Vitro Techniques; Kidney; Male; Perfusion; Rats; Rats, Wistar | 1998 |
Effects of propionyl-L-carnitine on cardiac dysfunction in streptozotocin-diabetic rats.
Topics: Administration, Oral; Animals; Blood Glucose; Cardiotonic Agents; Carnitine; Diabetes Mellitus, Experimental; Heart; Lipids; Male; Myocardium; Perfusion; Rats; Rats, Wistar; Ventricular Dysfunction, Left | 1998 |
[A new therapeutic proposal for intermittent claudication. Propionyl-L-carnitine: new indications concerning mechanism of action].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Viscosity; Cardiotonic Agents; Carnitine; Energy Metabolism; Humans; Intermittent Claudication; Microcirculation; Multicenter Studies as Topic; Rats | 1998 |
Propionyl-L-carnitine dilates human subcutaneous arteries through an endothelium-dependent mechanism.
Topics: Aged; Arteries; Carnitine; Dermis; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Humans; Male; Nitric Oxide; Prostaglandins; Vasodilation | 1999 |
L-propionyl carnitine reduces toxicity correlated to cyclosporine-induced intracellular ATP concentrations.
Topics: Adenosine Triphosphate; Animals; Cardiotonic Agents; Carnitine; Cyclosporine; Immunosuppressive Agents; In Vitro Techniques; Kidney Cortex; Male; Rats; Rats, Wistar | 1999 |
Cyclosporine-induced lipid peroxidation and propionyl carnitine protective effect.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carnitine; Cyclosporine; Drug Interactions; Immunosuppressive Agents; In Vitro Techniques; Kidney Cortex; Lipid Peroxidation; Rats | 1999 |
Beneficial effects of propionyl L-carnitine on sarcolemmal changes in congestive heart failure due to myocardial infarction.
Topics: Adenylyl Cyclases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium; Carnitine; Heart Failure; Male; Myocardial Infarction; Rats; Rats, Sprague-Dawley; Sarcolemma; Sodium-Calcium Exchanger; Sodium-Potassium-Exchanging ATPase; Time Factors; Ventricular Dysfunction, Left | 1999 |
Effects of L-carnitine and its acetyl and propionyl esters on ATP and PCr levels of isolated rat hearts perfused without fatty acids and investigated by means of 31P-NMR spectroscopy.
Topics: Acetylcarnitine; Adenosine Triphosphate; Animals; Carnitine; Energy Metabolism; Female; Heart; In Vitro Techniques; Magnetic Resonance Spectroscopy; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Perfusion; Phosphates; Phosphocreatine; Rats; Rats, Wistar | 1999 |
Identification of the mitochondrial carnitine carrier in Saccharomyces cerevisiae.
Topics: Acetylcarnitine; Amino Acid Transport Systems; Carnitine; Carrier Proteins; Chromatography, Affinity; Kinetics; Mitochondria; Mitochondrial Proteins; Molecular Sequence Data; Recombinant Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Substrate Specificity; Time Factors | 1999 |
Propionyl-L-carnitine as potential protective agent against adriamycin-induced impairment of fatty acid beta-oxidation in isolated heart mitochondria.
Topics: Adenosine Triphosphate; Animals; Antibiotics, Antineoplastic; Cardiotonic Agents; Carnitine; Carnitine O-Palmitoyltransferase; Doxorubicin; Fatty Acids; In Vitro Techniques; Male; Mitochondria, Heart; Myocardium; Oxidation-Reduction; Palmitates; Palmitoyl Coenzyme A; Proteins; Rats; Rats, Sprague-Dawley | 2000 |
beta-lactam antibiotics as substrates for OCTN2, an organic cation/carnitine transporter.
Topics: Acetylcarnitine; Animals; Anti-Bacterial Agents; Carnitine; Carrier Proteins; Cefadroxil; Cefepime; Cephaloridine; Cephalosporins; Dose-Response Relationship, Drug; HeLa Cells; Humans; Kinetics; Membrane Proteins; Nitrogen; Organic Cation Transport Proteins; Rats; Sodium; Solute Carrier Family 22 Member 5; Tumor Cells, Cultured | 2000 |
Evidence for a short-chain carnitine-acylcarnitine translocase in mitochondria specifically related to the metabolism of branched-chain amino acids.
Topics: Amino Acids, Branched-Chain; Biological Transport; Carnitine; Carnitine Acyltransferases; Cells, Cultured; Child; Deuterium; Fibroblasts; Humans; Intracellular Membranes; Isoleucine; Mass Spectrometry; Metabolism, Inborn Errors; Mitochondria; Oxidation-Reduction | 2000 |
Identification of undescribed medium-chain acylcarnitines present in urine of patients with propionic and methylmalonic acidemias.
Topics: Adult; Carboxy-Lyases; Carnitine; Case-Control Studies; Gas Chromatography-Mass Spectrometry; Humans; Infant; Lipid Metabolism, Inborn Errors; Male; Methylmalonic Acid; Methylmalonyl-CoA Decarboxylase; Propionates; Spectrometry, Mass, Fast Atom Bombardment | 2000 |
Propionyl-L-carnitine effects on postischemic recovery of heart function and substrate oxidation in the diabetic rat.
Topics: Animals; Cardiotonic Agents; Carnitine; Diabetes Mellitus, Experimental; Glucose; Heart; Male; Myocardial Ischemia; Myocardium; Palmitates; Rats; Rats, Sprague-Dawley; Recovery of Function | 2000 |
L -propionyl-carnitine as superoxide scavenger, antioxidant, and DNA cleavage protector.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Carnitine; DNA Damage; Dose-Response Relationship, Drug; Hydrogen Peroxide; Linoleic Acid; Lipid Peroxidation; Oxidants; Superoxides; Thiobarbituric Acid Reactive Substances; Ultraviolet Rays | 2000 |
Disposition of L-carnitine and its short-chain esters, acetyl-L-carnitine and propionyl-L-carnitine, in the rat isolated perfused liver.
Topics: Acetylcarnitine; Animals; Area Under Curve; Biological Availability; Cardiotonic Agents; Carnitine; Half-Life; In Vitro Techniques; Liver; Male; Nootropic Agents; Rats; Rats, Sprague-Dawley | 2000 |
[Treatment of chronic arterial occlusive disease of the lower limbs with propionyl-1-carnitine in elderly patients].
Topics: Aged; Arterial Occlusive Diseases; Cardiotonic Agents; Carnitine; Chronic Disease; Female; Humans; Leg; Male; Middle Aged | 2001 |
Effects of propionyl-L-carnitine on isolated mitochondrial function in the reperfused diabetic rat heart.
Topics: Animals; Blood Glucose; Body Weight; Cardiotonic Agents; Carnitine; Diabetes Mellitus, Experimental; Diastole; Heart; Heart Rate; In Vitro Techniques; Male; Mitochondria, Heart; Myocardial Reperfusion; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Systole | 2001 |
Propionyl-L-carnitine as protector against adriamycin-induced cardiomyopathy.
Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cardiomyopathies; Cardiotonic Agents; Carnitine; Doxorubicin; Female; Glutathione; In Vitro Techniques; Male; Malondialdehyde; Mice; Mitochondria, Heart; Oxidation-Reduction; Rats; Rats, Sprague-Dawley | 2001 |
Rapid diagnosis of methylmalonic and propionic acidemias: quantitative tandem mass spectrometric analysis of propionylcarnitine in filter-paper blood specimens obtained from newborns.
Topics: Amino Acid Metabolism, Inborn Errors; Blood Specimen Collection; Carnitine; False Positive Reactions; Humans; Infant, Newborn; Methylmalonic Acid; Paper; Propionates; Spectrometry, Mass, Electrospray Ionization | 2001 |
Propionyl-L-carnitine reduces intimal hyperplasia after injury in normocholesterolemic rabbit carotid artery by modulating proliferation and caspase 3-dependent apoptosis of vascular smooth muscle cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Biomarkers; Carnitine; Carotid Arteries; Caspase 3; Caspases; Cholesterol; Disease Models, Animal; Extracellular Matrix; Hyperplasia; Male; Muscle, Smooth, Vascular; Rabbits; Triglycerides; Tunica Intima | 2002 |
Propionyl-L-carnitine prevents renal function deterioration due to ischemia/reperfusion.
Topics: Animals; Carnitine; In Vitro Techniques; Ischemia; Kidney; Kidney Transplantation; Male; Rats; Rats, Sprague-Dawley; Renal Circulation; Reperfusion Injury; Transplantation, Isogeneic | 2002 |
Enhancement of muscular performance by a coformulation of propionyl-L-carnitine, coenzyme Q10, nicotinamide, riboflavin and pantothenic acid in the rat.
Topics: Animals; Antioxidants; Blood Pressure; Body Weight; Carnitine; Coenzymes; Drug Combinations; Energy Metabolism; Female; Heart; Heart Rate; Male; Motor Activity; Muscle, Skeletal; Muscle, Smooth; Niacinamide; Organ Size; Pantothenic Acid; Papillary Muscles; Rats; Rats, Wistar; Riboflavin; Sex Characteristics; Ubiquinone | 2002 |
Serum acylcarnitines and vitamin B12 deficiency.
Topics: Aged; Carnitine; Chromatography, High Pressure Liquid; Female; Humans; Male; Mass Spectrometry; Methylmalonic Acid; Middle Aged; Vitamin B 12 Deficiency | 2002 |
Gas chromatographic-mass spectrometric newborn screening for propionic acidaemia by targeting methylcitrate in dried filter-paper urine samples.
Topics: Carboxy-Lyases; Carnitine; Citrates; DNA Mutational Analysis; Gas Chromatography-Mass Spectrometry; Homozygote; Humans; Infant, Newborn; Male; Mass Spectrometry; Methylmalonyl-CoA Decarboxylase; Mutation, Missense; Neonatal Screening; Paper; Propionates | 2002 |
Unexpectedly high prevalence of the mild form of propionic acidemia in Japan: presence of a common mutation and possible clinical implications.
Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Carboxy-Lyases; Carnitine; Child, Preschool; Citrates; DNA Mutational Analysis; DNA Primers; Exons; Humans; Infant; Japan; Methylmalonyl-CoA Decarboxylase; Mutation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Prevalence; Propionates; RNA, Messenger | 2002 |
Exercise intolerance during post-MI heart failure in rats: prevention with supplemental dietary propionyl-L-carnitine.
Topics: Animals; Carnitine; Diet; Disease Models, Animal; Exercise Tolerance; Heart Failure; In Vitro Techniques; Myocardial Infarction; Rats; Rats, Inbred F344; Tissue Distribution; Ventricular Function, Left | 2003 |
Protective role of carnitine esters against alcohol-induced gastric lesions in rats.
Topics: Acetylcarnitine; Administration, Oral; Animals; Carnitine; Catalase; Ethanol; Gastric Mucosa; Glutathione; Glutathione Transferase; Male; Mice; Rats; Stomach Ulcer; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2003 |
Effects of L-carnitine and its derivatives on postischemic cardiac function, ventricular fibrillation and necrotic and apoptotic cardiomyocyte death in isolated rat hearts.
Topics: Acetylcarnitine; Animals; Apoptosis; Cardiotonic Agents; Carnitine; Heart; Ischemia; Myocardium; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Time Factors; Ventricular Fibrillation | 2003 |
Improvement of cardiac function and beta-adrenergic signal transduction by propionyl L-carnitine in congestive heart failure due to myocardial infarction.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cardiotonic Agents; Carnitine; Disease Models, Animal; Enzyme Activation; GTP-Binding Proteins; Heart Failure; Isoproterenol; Male; Models, Cardiovascular; Myocardial Infarction; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Signal Transduction; Stroke Volume; Ventricular Function | 2004 |
Effects of propionyl-carnitine on mitochondrial respiration and post-ischaemic cardiac function in the ischaemic underperfused diabetic rat heart.
Topics: Animals; Blood Pressure; Body Weight; Cardiotonic Agents; Carnitine; Diabetes Mellitus, Experimental; Heart Rate; In Vitro Techniques; Male; Mitochondria, Heart; Myocardial Ischemia; Myocardial Reperfusion; Oxygen Consumption; Rats; Rats, Sprague-Dawley | 2004 |
Enantio- and chemo-selective HPLC separations by chiral-achiral tandem-columns approach: the combination of CHIROBIOTIC TAG and SCX columns for the analysis of propionyl carnitine and related impurities.
Topics: Carnitine; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Stereoisomerism | 2004 |
Filter paper cards contaminated with EMLA cream produce artefacts on acylcarnitine analysis.
Topics: Carnitine; Chemistry, Clinical; Humans; Lidocaine; Prilocaine; Spectrometry, Mass, Electrospray Ionization; Time Factors | 2004 |
Prenatal diagnosis for organic acid disorders using two mass spectrometric methods, gas chromatography mass spectrometry and tandem mass spectrometry.
Topics: Amniotic Fluid; Carboxylic Acids; Carnitine; Female; Fetal Diseases; Gas Chromatography-Mass Spectrometry; Glutarates; Humans; Mass Spectrometry; Metabolism, Inborn Errors; Methylmalonic Acid; Pregnancy; Prenatal Diagnosis; Propionates; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Temperature | 2005 |
Uptake of L-carnitine and its short-chain ester propionyl-L-carnitine in the isolated perfused rat liver.
Topics: Animals; Bile; Carnitine; Liver; Male; Perfusion; Rats; Rats, Sprague-Dawley; Reproducibility of Results | 2005 |
L-carnitine and propionyl-L-carnitine improve endothelial dysfunction in spontaneously hypertensive rats: different participation of NO and COX-products.
Topics: Administration, Oral; Animals; Antioxidants; Aorta, Thoracic; Blood Pressure; Body Weight; Carnitine; Cyclooxygenase Inhibitors; Endothelium, Vascular; Epoprostenol; Hypertension; Male; Nitric Oxide; Nitric Oxide Synthase; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Thromboxane A2; Vasodilation | 2005 |
Antioxidant activity of propionyl-L-carnitine in liver and heart of spontaneously hypertensive rats.
Topics: Animals; Antioxidants; Blood Pressure; Carnitine; Catalase; Enzymes; Glutathione Peroxidase; Glutathione Reductase; Heart Ventricles; Hypertension; Lipid Peroxidation; Liver; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Triglycerides | 2006 |
Propionyl-L-carnitine prevents the progression of cisplatin-induced cardiomyopathy in a carnitine-depleted rat model.
Topics: Adenosine Triphosphate; Animals; Cardiomyopathies; Carnitine; Cisplatin; Disease Models, Animal; Glutathione; Heart; Male; Myocardium; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances | 2006 |
Changes of plasma fasting carnitine ester profile in patients with ulcerative colitis.
Topics: Adolescent; Adult; Aged; Carnitine; Colitis, Ulcerative; Fasting; Fatty Acids; Female; Humans; Male; Middle Aged | 2006 |
Two newborns with nutritional vitamin B12 deficiency: challenges in newborn screening for vitamin B12 deficiency.
Topics: Acyl-CoA Dehydrogenase, Long-Chain; Anemia, Pernicious; Autoimmune Diseases; Biomarkers; Carnitine; Citrates; Cystathionine; False Negative Reactions; Female; Gastric Bypass; Heterozygote; Homocysteine; Humans; Hydroxocobalamin; Infant Food; Infant, Newborn; Malabsorption Syndromes; Male; Mass Spectrometry; Maternal-Fetal Exchange; Methylmalonic Acid; Neonatal Screening; Pregnancy; Pregnancy Complications; Vitamin B 12 Deficiency | 2005 |
Protective effect of L-propionylcarnitine in chronic cyclosporine-a induced nephrotoxicity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Carnitine; Creatinine; Cyclosporine; Immunosuppressive Agents; Kidney Diseases; Lipid Peroxidation; Male; Rats; Rats, Wistar | 2006 |
Carnitine esters prevent oxidative stress damage and energy depletion following transient forebrain ischaemia in the rat hippocampus.
Topics: Acetylcarnitine; Adenosine Triphosphate; Animals; Carnitine; Disease Models, Animal; Energy Metabolism; Glutathione; Hippocampus; Ischemic Attack, Transient; Male; Nerve Degeneration; Neurons; Neuroprotective Agents; Nitrates; Nitrites; Oxidative Stress; Prosencephalon; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances | 2006 |
Propionyl-L-carnitine reduces proliferation and potentiates Bax-related apoptosis of aortic intimal smooth muscle cells by modulating nuclear factor-kappaB activity.
Topics: Animals; Aorta; Apoptosis; Base Sequence; bcl-2-Associated X Protein; Cardiotonic Agents; Carnitine; Dose-Response Relationship, Drug; G1 Phase; Male; Molecular Sequence Data; Muscle Proteins; Myocytes, Smooth Muscle; NF-kappa B; Rabbits; Rats; Rats, Wistar; S Phase; Tunica Intima; Up-Regulation | 2007 |
Carnitine deficiency provokes cisplatin-induced hepatotoxicity in rats.
Topics: Adenosine Triphosphate; Alanine Transaminase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Carnitine; Chemical and Drug Induced Liver Injury; Cisplatin; Disease Models, Animal; gamma-Glutamyltransferase; Glutathione; Liver; Liver Function Tests; Male; Nitrates; Nitrites; Oxidative Stress; Rats; Rats, Wistar; Risk Factors; Thiobarbituric Acid Reactive Substances; Vitamin B Deficiency | 2007 |
Editorial comment on: Antioxidant treatment associated with sildenafil reduces monocyte activation and markers of endothelial damage in patients with diabetic erectile dysfunction: a double-blind, placebo-controlled study.
Topics: Antioxidants; Carnitine; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Erectile Dysfunction; Humans; Male; Monocytes; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones | 2007 |
Editorial comment on: Antioxidant treatment associated with sildenafil reduces monocyte activation and markers of endothelial damage in patients with diabetic erectile dysfunction: a double-blind, placebo-controlled study.
Topics: Antioxidants; Carnitine; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Erectile Dysfunction; Humans; Male; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones | 2007 |
Effect of L-carnitine and propionyl-L-carnitine on endothelial function of small mesenteric arteries from SHR.
Topics: Animals; Biological Factors; Blood Pressure; Carbachol; Carnitine; Cyclooxygenase Inhibitors; Endothelium, Vascular; Hypertension; Indomethacin; Male; Mesenteric Arteries; Muscarinic Agonists; Nitric Oxide; Nitric Oxide Synthase Type III; Phenylephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Superoxides; Vasodilation; Vasodilator Agents | 2007 |
Rapid 2nd-tier test for measurement of 3-OH-propionic and methylmalonic acids on dried blood spots: reducing the false-positive rate for propionylcarnitine during expanded newborn screening by liquid chromatography-tandem mass spectrometry.
Topics: Blood Specimen Collection; Carnitine; Chromatography, Liquid; False Positive Reactions; Humans; Infant, Newborn; Lactic Acid; Methylmalonic Acid; Neonatal Screening; Predictive Value of Tests; Tandem Mass Spectrometry | 2007 |
l-carnitine and its propionate: improvement of endothelial function in SHR through superoxide dismutase-dependent mechanisms.
Topics: Animals; Antioxidants; Blood Pressure; Carnitine; Endothelium, Vascular; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Superoxide Dismutase; Superoxides | 2007 |
Propionyl-L-carnitine prevents age-related myocardial remodeling in the rabbit.
Topics: Aging; Animals; Cardiotonic Agents; Carnitine; Collagen; Collagen Type I; Disease Models, Animal; Endomyocardial Fibrosis; Fibroblasts; Immunohistochemistry; In Situ Nick-End Labeling; Male; Rabbits; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Vascular Cell Adhesion Molecule-1; Ventricular Remodeling | 2007 |
Metabolomics identifies perturbations in human disorders of propionate metabolism.
Topics: Acetylcarnitine; Adult; Amino Acid Metabolism, Inborn Errors; Betaine; Biomarkers; Carnitine; Child; Chromatography, High Pressure Liquid; Humans; Methylmalonic Acid; Plasma; Propionates; Spectrometry, Mass, Electrospray Ionization | 2007 |
Reversal of cisplatin-induced carnitine deficiency and energy starvation by propionyl-L-carnitine in rat kidney tissues.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antineoplastic Agents; Blood Urea Nitrogen; Carnitine; Cisplatin; Creatinine; Glutathione; Kidney Diseases; Male; Nitrates; Nitrites; Protective Agents; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances | 2007 |
Subacute presentation of propionic acidemia.
Topics: Acidosis; Amino Acids; Biotin; Brain; Carnitine; Diagnosis, Differential; Diet, Protein-Restricted; Disease Progression; Electrophoresis, Capillary; Gastroenteritis; Growth Disorders; Humans; Infant; Magnetic Resonance Imaging; Male; Metabolism, Inborn Errors; Propionates; Propionic Acidemia; Treatment Outcome; Vomiting | 2007 |
ATP production and TCA activity are stimulated by propionyl-L-carnitine in the diabetic rat heart.
Topics: Adenosine Triphosphate; Animals; Blood Glucose; Carnitine; Citric Acid Cycle; Diabetes Mellitus, Experimental; Male; Myocardium; Rats; Rats, Sprague-Dawley; Streptozocin | 2008 |
Prenatal diagnosis of methylmalonic aciduria by analysis of organic acids and total homocysteine in amniotic fluid.
Topics: Amniotic Fluid; Carnitine; Citrates; Female; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Male; Methylmalonic Acid; Pregnancy; Prenatal Diagnosis; Spectrometry, Mass, Electrospray Ionization | 2008 |
Neonatal vitamin B12 deficiency secondary to maternal subclinical pernicious anemia: identification by expanded newborn screening.
Topics: Anemia, Pernicious; Carnitine; Female; Humans; Infant, Newborn; Neonatal Screening; Pregnancy; Pregnancy Complications, Hematologic; Vitamin B 12 Deficiency | 2008 |
Increased C3-carnitine in a healthy premature infant.
Topics: Carnitine; Humans; Infant, Newborn; Infant, Premature; Male | 2008 |
Propionyl-L-carnitine prevents early graft dysfunction in allogeneic rat kidney transplantation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carnitine; Cyclosporine; Graft Survival; Kidney Cortex Necrosis; Kidney Transplantation; Neutrophil Infiltration; Protective Agents; Rats; Reperfusion Injury; Transplantation, Homologous | 2008 |
Positive inotropic effect of coenzyme Q10, omega-3 fatty acids and propionyl-L-carnitine on papillary muscle force-frequency responses of BIO TO-2 cardiomyopathic Syrian hamsters.
Topics: Animals; Cardiomyopathies; Cardiomyopathy, Dilated; Carnitine; Cricetinae; Fatty Acids, Omega-3; Male; Mesocricetus; Models, Animal; Myocardial Contraction; Papillary Muscles; Stimulation, Chemical; Ubiquinone | 2008 |
Comparison of pharmacokinetics of L-carnitine, acetyl-L-carnitine and propionyl-L-carnitine after single oral administration of L-carnitine in healthy volunteers.
Topics: Acetylcarnitine; Administration, Oral; Adult; Area Under Curve; Carnitine; Chromatography, High Pressure Liquid; Female; Half-Life; Humans; Male; Reference Values | 2009 |
Oral supplementation of propionyl-l-carnitine reduces body weight and hyperinsulinaemia in obese Zucker rats.
Topics: Animals; Carnitine; Dietary Supplements; Disease Models, Animal; Dose-Response Relationship, Drug; Eating; Endothelium, Vascular; Glucose Tolerance Test; Hemodynamics; Hyperinsulinism; Insulin Resistance; Lipids; Metabolic Syndrome; Obesity; Rats; Rats, Zucker; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Weight Gain | 2009 |
Stabilization of blood methylmalonic acid level in methylmalonic acidemia after liver transplantation.
Topics: Carnitine; Child; Child, Preschool; Female; Humans; Infant; Liver Transplantation; Male; Metabolism, Inborn Errors; Methylmalonic Acid; Methylmalonyl-CoA Mutase | 2010 |
Propionyl-L-carnitine improves postischemic blood flow recovery and arteriogenetic revascularization and reduces endothelial NADPH-oxidase 4-mediated superoxide production.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Vessels; Carnitine; Cell Proliferation; Chick Embryo; Chorioallantoic Membrane; Collateral Circulation; Disease Models, Animal; Endothelium, Vascular; Hindlimb; Humans; Intercellular Adhesion Molecule-1; Ischemia; Mice; NADPH Oxidase 4; NADPH Oxidases; Neovascularization, Physiologic; Rabbits; Regional Blood Flow; Superoxides; Vascular Endothelial Growth Factor A | 2010 |
Comparison of amino acids and acylcarnitines assay methods used in newborn screening assays by tandem mass spectrometry.
Topics: Amino Acids; Butanols; Carnitine; Humans; Infant, Newborn; Leucine; Metabolic Diseases; Methionine; Neonatal Screening; Palmitoylcarnitine; Phenylalanine; Quality Control; Tandem Mass Spectrometry | 2010 |
Useful second-tier tests in expanded newborn screening of isovaleric acidemia and methylmalonic aciduria.
Topics: Amino Acid Metabolism, Inborn Errors; Biomarkers; Blood Specimen Collection; Carnitine; Case-Control Studies; Chromatography, Liquid; False Positive Reactions; Gas Chromatography-Mass Spectrometry; Glycine; Humans; Infant, Newborn; Isovaleryl-CoA Dehydrogenase; Japan; Lactic Acid; Metabolism, Inborn Errors; Methylmalonic Acid; Neonatal Screening; Pilot Projects; Predictive Value of Tests; Retrospective Studies; Severity of Illness Index; Tandem Mass Spectrometry | 2010 |
Newborn screening for methylmalonic aciduria by tandem mass spectrometry: 7 years' experience from two centers in Taiwan.
Topics: Acetylcarnitine; Ammonia; Carnitine; Humans; Infant, Newborn; Methylmalonic Acid; Neonatal Screening; Taiwan; Tandem Mass Spectrometry | 2010 |
Clinical, biochemical, and molecular analysis of combined methylmalonic acidemia and hyperhomocysteinemia (cblC type) in China.
Topics: Amino Acid Metabolism, Inborn Errors; Biomarkers; Carnitine; Carrier Proteins; Child, Preschool; China; Codon, Nonsense; DNA Mutational Analysis; Exons; Gas Chromatography-Mass Spectrometry; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Heterozygote; Homocysteine; Homocystinuria; Homozygote; Humans; Infant; Infant, Newborn; Methylmalonic Acid; Oxidoreductases; Phenotype; Vitamin B 12 Deficiency | 2010 |
Rehabilitative treatment in peripheral artery disease: protocol application and follow-up.
Topics: Aged; Cardiotonic Agents; Carnitine; Clinical Protocols; Combined Modality Therapy; Diabetes Mellitus, Type 2; Exercise Therapy; Extremities; Female; Follow-Up Studies; Humans; Ischemia; Male; Middle Aged; Peripheral Arterial Disease; Regional Blood Flow; Walking | 2010 |
Expanded newborn screening for detection of vitamin B12 deficiency.
Topics: Carnitine; Female; Humans; Infant, Newborn; Minnesota; Neonatal Screening; Pregnancy; Pregnancy Complications; Reference Values; Vitamin B 12 Deficiency | 2011 |
Whole blood propionylcarnitine in newborns with orofacial cleft.
Topics: Carnitine; Case-Control Studies; Cleft Lip; Cleft Palate; Dietary Supplements; Female; Humans; Infant, Newborn; Male; Perinatal Care; Pregnancy; Retrospective Studies; Risk Factors; Tandem Mass Spectrometry; Vitamin B 12 Deficiency | 2011 |
Propionyl-L-carnitine, L-arginine and niacin in sexual medicine: a nutraceutical approach to erectile dysfunction.
Topics: Adult; Aged; Arginine; Carnitine; Dietary Supplements; Erectile Dysfunction; Humans; Male; Middle Aged; Niacin | 2012 |
Carnitine administration reduces cytokine levels, improves food intake, and ameliorates body composition in tumor-bearing rats.
Topics: Animals; Anorexia; Body Composition; Cachexia; Carnitine; Cytokines; Eating; Male; Neoplasms, Experimental; Rats; Rats, Inbred F344 | 2011 |
Living-donor liver transplantation for propionic acidemia.
Topics: Carnitine; Child, Preschool; Citrates; Female; Humans; Infant; Liver Transplantation; Living Donors; Postoperative Complications; Propionic Acidemia; Quality of Life; Retrospective Studies; Treatment Outcome | 2012 |
Propionyl-L-carnitine corrects metabolic and cardiovascular alterations in diet-induced obese mice and improves liver respiratory chain activity.
Topics: Animals; Body Weight; Carnitine; Diet; Electron Transport; Feeding Behavior; Liver; Mice; Mice, Inbred C57BL; Organ Size | 2012 |
Effect of short- and long-term treatment with valproate on carnitine homeostasis in humans.
Topics: Acetylcarnitine; Adult; Betaine; Biological Transport; Carnitine; Cell Line; Drug Administration Schedule; Female; HEK293 Cells; Homeostasis; Humans; Kidney Tubules, Proximal; Organic Cation Transport Proteins; Solute Carrier Family 22 Member 5; Valproic Acid | 2012 |
Propionyl-L-carnitine hydrochloride for treatment of mild to moderate colonic inflammatory bowel diseases.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Carnitine; Female; Humans; Inflammatory Bowel Diseases; Male; Middle Aged; Prospective Studies | 2012 |
[Analysis of propionylcarnitine in blood and methylmalonic acid in urine of 162 patients with methylmalonic acidemia].
Topics: Acetylcarnitine; Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Carnitine; Case-Control Studies; Child; Child, Preschool; Female; Gas Chromatography-Mass Spectrometry; Humans; Infant; Infant, Newborn; Male; Methylmalonic Acid; Tandem Mass Spectrometry; Young Adult | 2013 |
[Outcomes of patients with combined methylmalonic acidemia and homocystinuria after treatment].
Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Betaine; Carnitine; Child; Child, Preschool; Female; Follow-Up Studies; Homocystine; Homocystinuria; Humans; Hydroxocobalamin; Infant; Infant, Newborn; Male; Methylmalonic Acid; Neonatal Screening; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2013 |
Metabolic characterization of hepatocellular carcinoma using nontargeted tissue metabolomics.
Topics: Adult; Aged; Antioxidants; Betaine; Carcinoma, Hepatocellular; Carnitine; Citric Acid Cycle; Fatty Acid Desaturases; Fatty Acids, Unsaturated; Female; Gluconeogenesis; Glutathione; Glycolysis; Hepatitis, Chronic; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Metabolome; Metabolomics; Middle Aged; Phospholipases A2 | 2013 |
Betaine supplementation causes increase in carnitine metabolites in the muscle and liver of mice fed a high-fat diet as studied by nontargeted LC-MS metabolomics approach.
Topics: Acetylcarnitine; Adipose Tissue; Adiposity; Animals; Betaine; Blood Glucose; Carnitine; Chromatography, Liquid; Diet, High-Fat; Dietary Supplements; Fasting; Glucans; Insulin; Leptin; Lipid Metabolism; Liver; Male; Mass Spectrometry; Metabolomics; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Obesity; Triglycerides; Weight Gain | 2013 |
Identification and assay of underivatized urinary acylcarnitines by paper spray tandem mass spectrometry.
Topics: Adult; Calibration; Carnitine; Humans; Limit of Detection; Paper; Reproducibility of Results; Tandem Mass Spectrometry; Young Adult | 2013 |
Effect of carnitine, acetyl-, and propionylcarnitine supplementation on the body carnitine pool, skeletal muscle composition, and physical performance in mice.
Topics: Acetylcarnitine; Administration, Oral; Animals; Biological Availability; Biomarkers; Carnitine; Dietary Supplements; Energy Metabolism; Liver; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Oxidative Stress; Oxygen Consumption; Physical Conditioning, Animal | 2014 |
Identification of predictive biomarkers of disease state in transition dairy cows.
Topics: Animals; Biomarkers; Carnitine; Cattle; Cattle Diseases; Cross-Sectional Studies; Female; Lactation; Longitudinal Studies; Lysophosphatidylcholines; Parturition; Postpartum Period; Puerperal Disorders | 2014 |
Maternal vitamin B12 deficiency detected in expanded newborn screening.
Topics: Carnitine; Female; Folic Acid; Homocysteine; Humans; Infant, Newborn; Methylmalonic Acid; Neonatal Screening; Pregnancy; Pregnancy Complications; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2014 |
Antioxidant treatment prevents serum deprivation- and TNF-α-induced endothelial dysfunction through the inhibition of NADPH oxidase 4 and the restoration of β-oxidation.
Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Carnitine; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Coculture Techniques; Cytokines; Cytoprotection; Enzyme Inhibitors; Human Umbilical Vein Endothelial Cells; Humans; Leukocytes; Mitochondria; NADPH Oxidase 4; NADPH Oxidases; Naphthoquinones; Oxidation-Reduction; Oxidative Stress; RNA Interference; Serum; Transfection; Tumor Necrosis Factor-alpha | 2014 |
In HepG2 cells, coexisting carnitine deficiency masks important indicators of marginal biotin deficiency.
Topics: Acyl Coenzyme A; Biomarkers; Biotin; Carnitine; Chromatography, Liquid; Culture Media; False Negative Reactions; Female; Hep G2 Cells; Humans; Pregnancy; Tandem Mass Spectrometry | 2015 |
Long-term sex-biased correction of circulating propionic acidemia disease markers by adeno-associated virus vectors.
Topics: Animals; Biomarkers; Carnitine; Citrates; Dependovirus; Female; Genetic Therapy; Genetic Vectors; Injections, Intravenous; Liver; Luciferases; Male; Methylmalonyl-CoA Decarboxylase; Mice; Muscle, Skeletal; Propionic Acidemia; Real-Time Polymerase Chain Reaction; Sex Characteristics | 2015 |
[Acute encephalopathy induced by vaccination in an infant with methylmalonic aciduria cblA].
Topics: Amino Acid Metabolism, Inborn Errors; Brain Diseases; Carnitine; Diet, Protein-Restricted; Hepatitis B Vaccines; Humans; Infant; Male; Methylmalonic Acid; Mutation; Vaccination; Vitamin B Complex; Vomiting | 2015 |
Serum vitamin B12 levels during the first trimester of pregnancy correlate with newborn screening markers of vitamin B12 deficiency.
Topics: Acetylcarnitine; Adolescent; Adult; Biomarkers; Carnitine; Diet; Female; Gestational Age; Humans; Infant, Newborn; Maternal Welfare; Meat; Neonatal Screening; Nutritional Status; Pregnancy; Pregnancy Complications; Pregnancy Trimester, Third; Smoking; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2014 |
Biochemical, molecular and outcome analysis of eight chinese asymptomatic individuals with methyl malonic acidemia detected through newborn screening.
Topics: Acetylcarnitine; Acidosis; Asian People; Asymptomatic Diseases; Carboxy-Lyases; Carnitine; Carrier Proteins; Child; Citrates; Female; Gene Expression; Humans; Infant; Infant, Newborn; Male; Malonates; Malonyl Coenzyme A; Metabolism, Inborn Errors; Methylmalonic Acid; Methylmalonyl-CoA Mutase; Mutation; Neonatal Screening; Oxidoreductases | 2015 |
Urine and serum metabolomic profiling reveals that bile acids and carnitine may be potential biomarkers of primary biliary cirrhosis.
Topics: Adult; Aged; Bile Acids and Salts; Biomarkers; Carnitine; Chromatography, High Pressure Liquid; Female; Humans; Liver Cirrhosis, Biliary; Male; Mass Spectrometry; Metabolome; Metabolomics; Middle Aged | 2015 |
Propionyl-L-Carnitine Enhances Wound Healing and Counteracts Microvascular Endothelial Cell Dysfunction.
Topics: Animals; Blood Flow Velocity; Carnitine; Dermis; Endothelial Cells; Humans; Male; Microcirculation; NADPH Oxidase 4; NADPH Oxidases; Neovascularization, Physiologic; Nitric Oxide; Nitric Oxide Synthase Type II; Placenta Growth Factor; Pregnancy Proteins; Rats; Rats, Wistar; Reactive Oxygen Species; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2; Wound Healing | 2015 |
Low levels of short- and medium-chain acylcarnitines in HIV-infected patients.
Topics: Adult; Antiretroviral Therapy, Highly Active; Carnitine; Case-Control Studies; Disease Progression; Female; HIV Infections; Humans; Interferon-gamma; Interferon-gamma Release Tests; Longitudinal Studies; Male; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Tumor Necrosis Factor-alpha | 2016 |
[Clinical and laboratory studies on four Chinese patients with succinate-CoA ligase deficiency noticed by mild methylmalonic aciduria].
Topics: Amino Acid Metabolism, Inborn Errors; Asian People; Carnitine; Diagnosis, Differential; DNA Mutational Analysis; Humans; Infant; Infant, Newborn; Magnetic Resonance Imaging; Methylmalonic Acid; Mitochondrial Diseases; Mutation; Succinate-CoA Ligases | 2016 |
Quantification of 2-methylcitric acid in dried blood spots improves newborn screening for propionic and methylmalonic acidemias.
Topics: Acetylcarnitine; Algorithms; Amino Acid Metabolism, Inborn Errors; Biomarkers; Carnitine; Chromatography, Liquid; Citrates; Dried Blood Spot Testing; False Positive Reactions; Humans; Infant, Newborn; Methylmalonic Acid; Neonatal Screening; Predictive Value of Tests; Reference Values; Referral and Consultation; Reproducibility of Results; Tandem Mass Spectrometry | 2017 |
Quantitative analysis of amino acids and acylcarnitines combined with untargeted metabolomics using ultra-high performance liquid chromatography and quadrupole time-of-flight mass spectrometry.
Topics: Aged; Amino Acids; Biomarkers; Carnitine; Chromatography, High Pressure Liquid; Female; Humans; Limit of Detection; Male; Metabolomics; Middle Aged; Spectrometry, Mass, Electrospray Ionization | 2016 |
Novel Mouse Models of Methylmalonic Aciduria Recapitulate Phenotypic Traits with a Genetic Dosage Effect.
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Animals; Biomarkers; Brain; Carnitine; Dietary Proteins; Disease Models, Animal; Gene Dosage; Gene Knock-In Techniques; Kidney; Methylmalonic Acid; Methylmalonyl-CoA Mutase; Mice; Mice, Knockout; Phenotype; Quantitative Trait, Heritable | 2016 |
Improvement in the prognosis and development of patients with methylmalonic acidemia after living donor liver transplant.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Carnitine; Child; Child, Preschool; Diet, Protein-Restricted; Female; Follow-Up Studies; Humans; Japan; Liver Failure; Liver Transplantation; Living Donors; Male; Prognosis; Quality of Life; Surveys and Questionnaires; Treatment Outcome | 2016 |
Changes in the levels of l-carnitine, acetyl-l-carnitine and propionyl-l-carnitine are involved in perfluorooctanoic acid induced developmental cardiotoxicity in chicken embryo.
Topics: Acetylcarnitine; Animals; Blotting, Western; Caprylates; Cardiotoxicity; Carnitine; Chick Embryo; Chickens; Chromatography, Liquid; Dose-Response Relationship, Drug; Electrocardiography; Environmental Pollutants; Fluorocarbons; Heart; Myocardium; Tandem Mass Spectrometry | 2016 |
Metabolomic signatures of low birthweight: Pathways to insulin resistance and oxidative stress.
Topics: Adolescent; Adult; Aged; Carnitine; Cohort Studies; Dipeptides; Female; Fetal Growth Retardation; Finland; Humans; Hydroxybutyrates; Infant, Low Birth Weight; Infant, Newborn; Insulin Resistance; Male; Metabolome; Metabolomics; Middle Aged; Oxidative Stress; Phenylpropionates; Pregnancy; Sex Factors; Twins; United Kingdom; Young Adult | 2018 |
A liposome-based formulation containing equol, dihomo-γ-linolenic acid and propionyl-l-carnitine to prevent and treat hair loss: A prospective investigation.
Topics: 8,11,14-Eicosatrienoic Acid; Administration, Cutaneous; Adult; Alopecia; Carnitine; Drug Combinations; Equol; Female; Hair Follicle; Humans; Liposomes; Male; Middle Aged; Pilot Projects; Prospective Studies; Scalp; Time Factors; Treatment Outcome | 2019 |
Newborn screening for homocystinurias: Recent recommendations versus current practice.
Topics: Acetylcarnitine; Amino Acid Metabolism, Inborn Errors; Carnitine; Female; Glycine N-Methyltransferase; Homocysteine; Homocystinuria; Humans; Infant, Newborn; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Muscle Spasticity; Neonatal Screening; Phenylalanine; Psychotic Disorders | 2019 |
Indication of metabolic inflexibility to food intake in spontaneously overweight Labrador Retriever dogs.
Topics: Animals; Carnitine; Dog Diseases; Dogs; Eating; Lipid Metabolism; Male; Overweight; Phospholipids | 2019 |
Determination of methylmalonic acid, 2-methylcitric acid, and total homocysteine in dried blood spots by liquid chromatography-tandem mass spectrometry: A reliable follow-up method for propionylcarnitine-related disorders in newborn screening.
Topics: Carnitine; Chromatography, Liquid; Citrates; Follow-Up Studies; Homocysteine; Humans; Infant; Infant, Newborn; Methylmalonic Acid; Neonatal Screening; Prospective Studies; Retrospective Studies; Tandem Mass Spectrometry | 2021 |
Diagnostic Challenges Using a 2-Tier Strategy for Methylmalonic Acidurias: Data from 1.2 Million Dried Blood Spots.
Topics: Amino Acid Metabolism, Inborn Errors; Carnitine; Diagnosis, Differential; Dried Blood Spot Testing; Female; Humans; Infant, Newborn; Male; Methylmalonic Acid; Neonatal Screening; Pilot Projects; Vitamin B 12 Deficiency | 2020 |
Proteinuria as a presenting sign of combined methylmalonic acidemia and homocysteinemia: case report.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Amino Acids; Base Sequence; Carnitine; Child, Preschool; DNA; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylmalonic Acid; Proteinuria | 2020 |
Mechanistic perspectives on differential mitochondrial-based neuroprotective effects of several carnitine forms in Alzheimer's disease in vitro model.
Topics: Acetylcarnitine; Alzheimer Disease; Animals; Apoptosis; Carnitine; Cells, Cultured; Female; Hippocampus; Membrane Potential, Mitochondrial; Mitochondria; Neurons; Neuroprotective Agents; Oxygen Consumption; Rats; Rats, Wistar | 2021 |
Late-onset cblC defect: clinical, biochemical and molecular analysis.
Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Carnitine; Child; Child, Preschool; Homocystinuria; Humans; Methylmalonic Acid; Mutation; Oxidoreductases; Vitamin B 12; Young Adult | 2023 |
Genetic and Lifestyle-Related Factors Influencing Serum Hyper-Propionylcarnitine Concentrations and Their Association with Metabolic Syndrome and Cardiovascular Disease Risk.
Topics: Aged; Amino Acids; Cardiovascular Diseases; Carnitine; Genome-Wide Association Study; Humans; Kinesins; Life Style; Metabolic Syndrome; Middle Aged; Risk Factors | 2023 |