carnitine and phenytoin

carnitine has been researched along with phenytoin in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19904 (30.77)18.7374
1990's4 (30.77)18.2507
2000's2 (15.38)29.6817
2010's3 (23.08)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Alonso, C; Camiña, MF; Gómez, M; Paz, JM; Rodriguez-Segade, S; Rozas, I1
Alonso, C; Camiña, MF; Castro-Gago, M; Paz, JM; Rodriguez-Segade, S; Rozas, I1
Bates, SR; Hug, G; Landrigan, EA; McGraw, CA1
Albani, F; Baruzzi, A; Campostrini, R; Galli, G; Paganini, M; Riva, R; Zaccara, G1
de la Peña, CA; Del Río, R; Fernandez, MP; Paz, JM; Rodriguez-Segade, S; Rozas, I; Tutor, JC1
Madappally, MW; Mehlman, MA; Ruegamer, WR; Tobin, RB1
Colton, DG; Elfont, EA; Mehlman, MA; Tobin, RB1
Kaeser, HE1
Gau, CS; Lin, CJ; Liou, HH; Shyu, MK; Wu, SP1
Fagiolino, P; González, R; Guevara, N; Maldonado, C; Queijo, C; Vázquez, M1

Reviews

1 review(s) available for carnitine and phenytoin

ArticleYear
Drug-induced myasthenic syndromes.
    Acta neurologica Scandinavica. Supplementum, 1984, Volume: 100

    Topics: Adrenergic beta-Antagonists; Adult; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Autoimmune Diseases; Baclofen; Carnitine; Collagen Diseases; Diazepam; Female; Humans; Male; Middle Aged; Muscular Diseases; Myasthenia Gravis; Neuromuscular Junction; Penicillamine; Phenytoin; Streptomycin; Synaptic Transmission; Syndrome

1984

Trials

1 trial(s) available for carnitine and phenytoin

ArticleYear
Carnitine and/or Acetylcarnitine Deficiency as a Cause of Higher Levels of Ammonia.
    BioMed research international, 2016, Volume: 2016

    Topics: Acetylcarnitine; Adolescent; Adult; Aged; Aged, 80 and over; Ammonia; Bipolar Disorder; Carnitine; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Valproic Acid

2016

Other Studies

11 other study(ies) available for carnitine and phenytoin

ArticleYear
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Short-term effects of administration of anticonvulsant drugs on free carnitine and acylcarnitine in mouse serum and tissues.
    British journal of pharmacology, 1991, Volume: 103, Issue:1

    Topics: Animals; Anticonvulsants; Carbamazepine; Carnitine; Heart; In Vitro Techniques; Male; Mice; Muscles; Myocardium; Phenobarbital; Phenytoin; Prohibitins; Valproic Acid

1991
Alteration of renal carnitine metabolism by anticonvulsant treatment.
    Neurology, 1991, Volume: 41, Issue:9

    Topics: Ammonia; Animals; Anticonvulsants; Carbamazepine; Carnitine; Male; Mice; Phenobarbital; Phenytoin; Valproic Acid

1991
Reduction of serum carnitine concentrations during anticonvulsant therapy with phenobarbital, valproic acid, phenytoin, and carbamazepine in children.
    The Journal of pediatrics, 1991, Volume: 119, Issue:5

    Topics: Analysis of Variance; Carbamazepine; Carnitine; Child; Drug Combinations; Fatty Acids; Fatty Acids, Volatile; Humans; Phenobarbital; Phenytoin; Seizures; Valproic Acid

1991
Effects of acute valproic acid administration on carnitine plasma concentrations in epileptic patients.
    Epilepsy research, 1991, Volume: 8, Issue:2

    Topics: Adult; Ammonia; Carnitine; Epilepsy; Humans; Phenobarbital; Phenytoin; Valproic Acid

1991
Carnitine deficiency associated with anticonvulsant therapy.
    Clinica chimica acta; international journal of clinical chemistry, 1989, May-15, Volume: 181, Issue:2

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Carnitine; Cerebral Palsy; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Seizures; Valproic Acid

1989
Mode of action of 5,5'-diphenylthiohydantoin-sites of action of 5,5'-diphenylthiohydantoin in mitochondria in relationship to thyroxine-stimulated responses.
    Biochemical pharmacology, 1972, Aug-01, Volume: 21, Issue:15

    Topics: Animals; Binding Sites; Carbon Isotopes; Carboxy-Lyases; Carnitine; Diet; Dinitrophenols; Drug Interactions; Fructose-Bisphosphatase; Gluconeogenesis; Glucose-6-Phosphatase; Glycerophosphates; In Vitro Techniques; Ligases; Liver; Methimazole; Mitochondria, Liver; Oxygen Consumption; Phenytoin; Pyruvates; Rats; Succinates; Sulfides; Thyroxine

1972
Ultrastructural and biochemical alterations of livers from rats treated with 5,5-diphenyl-2-thiohydantoin (DPTH) and thyroxine.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1972, Volume: 141, Issue:1

    Topics: Acetoacetates; Animals; Caprylates; Carnitine; DNA; Endoplasmic Reticulum; Fatty Acids; Hydroxybutyrates; Lipid Metabolism; Liver; Liver Glycogen; Male; Microscopy, Electron; Mitochondria, Liver; Organ Size; Phenytoin; Proteins; Rats; RNA; Sulfides; Thyroxine

1972
Interaction between anticonvulsants and human placental carnitine transporter.
    Epilepsia, 2004, Volume: 45, Issue:3

    Topics: Acetates; Amines; Aminoisobutyric Acids; Anticonvulsants; Carnitine; Carrier Proteins; Culture Techniques; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Models, Biological; Nipecotic Acids; Organic Cation Transport Proteins; Phenytoin; Placenta; Pregnancy; Pregnancy Complications; Pregnancy Proteins; Solute Carrier Family 22 Member 5; Tiagabine; Topiramate; Triazines; Valproic Acid; Vigabatrin

2004