carnitine has been researched along with palmitoylcarnitine in 166 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 89 (53.61) | 18.7374 |
| 1990's | 37 (22.29) | 18.2507 |
| 2000's | 16 (9.64) | 29.6817 |
| 2010's | 24 (14.46) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Berge, R; Farstad, M | 1 |
| Kähönen, M | 1 |
| Entman, ML; Pitts, BJ; Tate, CA; Van Winkle, WB; Wood, JM | 1 |
| Adams, RJ; Cohen, DW; Gupte, S; Johnson, JD; Schwartz, A; Wallick, ET; Wang, T | 1 |
| Saggerson, ED; Smith, SJ | 1 |
| Adams, RJ; Gende, OA; Pitts, BJ; Schwartz, A; Wallick, ET; Woods, JM | 1 |
| Harati, Y; Hefferan, P; Howell, RR; Patten, BM; Wood, JM | 1 |
| Berge, RK; Farstad, M; Hagen, LE | 1 |
| Gregersen, N | 1 |
| Li, TK; Williams, ES | 1 |
| Wood, JM | 1 |
| Dargel, R; Seim, H | 1 |
| Borrebaek, B; Norlund, AE | 1 |
| Busch, U; Chang, CH; Entman, ML; Hanley, HG; Hartley, CJ; Lewis, RM; Morgan, WJ; Schwartz, A; Swain, JA; Wood, JM | 1 |
| Aynsley-Green, A; Bartlett, K; Bhuiyan, AK; Jackson, S; Leonard, JV; Turnbull, DM | 1 |
| Benedict, CR; Bick, RJ; McMillin, JB | 1 |
| Nozu, F; Takeyama, N; Tanaka, T | 1 |
| Chiodi, P; Maccari, F; Ramacci, MT | 1 |
| Criddle, DN; Dewar, GH; Wathey, WB; Woodward, B | 1 |
| Bigaud, M; Dainty, IA; McGrath, JC; Spedding, M | 1 |
| Arrigoni Martelli, E; Bassani, E; Cardace, G; Corbelletta, C; Mancinelli, A; Marzo, A; Solbiati, M | 1 |
| Baxter, CF; Schulz, H; Wang, HY | 1 |
| Squire, RS | 1 |
| McMurray, WC; Mok, AY | 1 |
| Man, RY; Mock, T | 1 |
| Stinson, RH | 1 |
| Mészàros, J; Pappano, AJ | 1 |
| Krejcí, V; Martínková, J; Parízek, J; Tilser, I; Volenec, K | 1 |
| Mir, AK; Spedding, M | 1 |
| Grosman, N | 1 |
| Duncan, GP; Patmore, L; Spedding, M | 1 |
| Boeynaems, JM; Pirotton, S; Ramboer, I | 1 |
| Hayashi, H; Kobayashi, A; Watanabe, H; Yamazaki, N | 1 |
| Fujisawa, S; Kobayashi, A; Watanabe, H; Yamamoto, T; Yamazaki, N | 1 |
| Hayashi, H; Kobayashi, A; Sakata, K; Yamazaki, N | 1 |
| Hironaka, Y; Ohara, N; Yokota, S | 1 |
| Classen, J; Deuticke, B; Haest, CW | 1 |
| Brass, EP | 1 |
| Boscoboinik, D; Epand, RM | 1 |
| Corr, PB; Heathers, GP; Kanter, EM; Yamada, KA | 1 |
| Petzold, D; Schönfeld, P | 1 |
| Alexander, J; Engle, K; Fix, JA; Gardner, CR; Leppert, PS; Porter, PA; Selk, SJ | 1 |
| Baydoun, AR; Markham, A; Morgan, RM; Sweetman, AJ | 1 |
| Kramer, JH; Weglicki, WB | 1 |
| Hassinen, IE; Hiltunen, JK; Kärki, TT; Latipää, PM | 1 |
| Brass, EP; Gibbons, AP; Hoppel, CL; Turkaly, JS | 1 |
| Aizu, E; Kato, R; Nakadate, T; Yamamoto, S | 1 |
| Brockenbrough, JS; Korc, M | 1 |
| McMillin, JB; Pauly, DF; Yoon, SB | 1 |
| Dobesová, Z; Drahota, Z; Krasinskaya, IP; Mourek, J; Rauchová, H | 1 |
| Kremer, B; Matrat, M; Nabet, P; Ramacci, C; Vescovi, G; Weber, B | 1 |
| Bartlett, K; Bhuiyan, AK; Sherratt, HS; Turnbull, DM; Watmough, NJ | 1 |
| Brady, LJ; Brady, PS; Colucci, WJ; Gandour, RD; Stelly, TC | 1 |
| Busselen, P; Sercu, D; Verdonck, F | 1 |
| Mészáros, J; Pappano, AJ; Villanova, L | 1 |
| Aomine, M; Arita, M; Shimada, T | 1 |
| Madhukar, BV; Oh, SY; Trosko, JE | 1 |
| Aizu, E; Kato, R; Kiyoto, I; Nakadate, T; Yamamoto, S | 1 |
| Eacho, PI; Foxworthy, PS | 1 |
| Aomine, M; Arita, M | 1 |
| Blumberg, PM; Nakadate, T | 1 |
| Brady, LJ; Brady, PS; Dunker, AK | 1 |
| De Jonge-Stinis, JT; Hülsmann, WC; Lamers, JM; Verdouw, PD | 1 |
| Bentham, JM; Higgins, AJ; Woodward, B | 1 |
| Ramsay, RR; Tubbs, PK | 1 |
| Deaciuc, IV; Kuhnle, HF; Schmidt, FH | 1 |
| Novak, M; Penn, D; Prögler, M; Schmidt-Sommerfeld, E; Schneider, H; Sodha, RJ | 1 |
| Dubelaar, ML; Hülsmann, WC; Lamers, JM; Maccari, F | 1 |
| De Villiers, M; Lochner, A | 1 |
| Brosnan, JT; Reid, K | 1 |
| Ahumada, GG; Knabb, MT; Saffitz, JE; Sobel, BE | 1 |
| Zammit, VA | 1 |
| Bjørnstad, K; Osmundsen, H | 1 |
| Imai, S; Matsui, K; Nakazawa, M; Takeda, K | 1 |
| Okhuysen, CH; Pitts, BJ | 1 |
| McMillin-Wood, J; Wolkowicz, PE | 1 |
| Helfman, DM; Katoh, N; Kuo, JF; Wrenn, RW | 1 |
| Inoue, D; Pappano, AJ | 1 |
| Kato, R; Mita, S; Nakadate, T; Nakaki, T; Yamamoto, S | 1 |
| Abe, M; Kobayashi, A; Ohta, H; Suzuki, Y; Yamazaki, N | 1 |
| Hülsmann, WC; Lamers, JM; Montfoort, A; Stinis, HT | 1 |
| Murthy, MS; Pande, SV | 1 |
| Gross, RW | 1 |
| Bell, FP | 1 |
| Bieber, LL; Fishlock, RC; Snoswell, AM | 1 |
| Ahumada, GG; Gross, RW; Sobel, BE | 1 |
| Ballantyne, JS; Storey, KB | 1 |
| Greenwood, MR; Sullivan, AC; Triscari, J | 1 |
| Gross, RW; Sobel, BE | 2 |
| Kuo, JF; Wise, BC | 1 |
| Bell, FP; DeLucia, AJ | 1 |
| Katz, S; Lopaschuk, GD; McNeill, JH | 1 |
| Katoh, N; Kuo, JF; Shoji, M; Wise, BC; Wrenn, RW | 1 |
| Hayashi, H; Kamikawa, T; Kobayashi, A; Masumura, Y; Suzuki, Y; Yamazaki, N | 1 |
| Hülsmann, WC; Maccari, F; Stam, H | 1 |
| Katz, AM; Messineo, FC; Pinto, PB | 1 |
| Pande, SV | 1 |
| Arinze, IJ; Parameswaran, M | 1 |
| Cain, ME; Corr, PB; Crafford, WA; Gross, RW; Snyder, DW; Sobel, BE | 1 |
| Brass, EP; Hoppel, CL | 1 |
| Lee, CP; Martens, ME | 1 |
| Allely, MC; Brown, CM; Kenny, BA; Kilpatrick, AT; Martin, A; Spedding, M | 1 |
| Epand, RM; McCallum, CD | 1 |
| Hsu, CY; Tune, BM | 1 |
| Coronado, R; el-Hayek, R; Hogan, K; Valdivia, C; Valdivia, HH | 1 |
| Ford, GD; Packer, L; Suzuki, YJ | 1 |
| Butterfield, DA; Rangachari, A | 1 |
| Arduini, A; Arrigoni-Martelli, E; Dottori, S; Federici, G; Gorbunov, N; Molajoni, F; Russo, F | 1 |
| Bellard, BM; Fronczek, FR; Gandour, RD; Greway, AT; Kumaravel, G; Leung, OT; Nic a'Bháird, N; Ramsay, RR | 1 |
| Alonso, A; Goñi, FM; Requero, MA | 1 |
| Arduini, A; Calvani, M; Dottori, S; Peschechera, A; Sciarroni, AF; Serafini, F | 1 |
| Clarke, B; May, GR; McCormack, JG; Wyatt, KM | 1 |
| Biselli, R; De Simone, C; Farrace, S; Fattorossi, A | 1 |
| Paradies, G; Petrosillo, G; Quagliariello, E; Ruggiero, FM | 1 |
| Costa, CG; de Almeida, IT; Dorland, L; Duran, M; IJlst, L; Jakobs, C; Ventura, FV; Wanders, RJ | 1 |
| Chalmers, RA; English, N; Stanley, CA; Wigglesworth, JS | 1 |
| Berent, U; Mroczkowska, JE; Nałecz, KA; Nałecz, MJ | 1 |
| Hatakeyama, S; Koni, I; Mabuchi, H; Matsumura, M | 1 |
| Rozanski, GJ; Xu, Z | 1 |
| Longo, N; Scaglia, F; Wang, Y | 1 |
| Elliott, KR; Krauss, S; New, KJ; Quant, PA | 1 |
| al Aqeel, AI; Rashed, MS; Wanders, RJ | 1 |
| Aleck, K; Ding, JH; Grebe, TA; He, G; Roe, CR; Roe, DS; Teramoto, R; Yang, BZ | 1 |
| Barbarisi, A; Benatti, P; Calvani, M; Nicolai, R; Peluso, G; Reda, E | 1 |
| Kanter, EM; Newatia, A; Yamada, KA | 1 |
| Adachi, S; Babior, BM; Esser, V; Gottlieb, RA; Konyavko, M; McGarry, JD; Mutomba, MC; Yokoyama, CB; Yuan, H | 1 |
| Blakely, JA; Johnson, MD; Stewart, JM | 1 |
| Liobikas, J; Majiene, D; Toleikis, A; Trumbeckaite, S | 1 |
| Bauer, MF; Gempel, K; Gerbitz, KD; Hofmann, S; Rettinger, A | 1 |
| Bauer, MF; Bieger, I; Gempel, K; Gerbitz, KD; Hofmann, S; Kiechl, S; Kiechl-Kohlendorfer, U; Lochmüller, H; Pongratz, D; Rettinger, A; Sperl, W; Willeit, J | 1 |
| Aburatani, H; Fukada, S; Ikeda, K; Matsuura, A; Nimura, Y; Sato, N; Sekoguchi, E; Yasui, A | 1 |
| BREMER, J | 1 |
| Bali, D; Gregersen, N; Koeberl, DD; Liu, HM; Matern, D; Millington, DS; Stevens, RD; Young, SP | 1 |
| Gooding, JM; Saggerson, ED; Shayeghi, M | 1 |
| Dai, J; Liu, H; Treber, M; Woldegiorgis, G; Zheng, G | 1 |
| Hoppel, CL; Ingalls, ST; Minkler, PE | 1 |
| Daniel, H; Nickel, A; Wenzel, U | 2 |
| Bøersheim, E; Cree, MG; Sun, D; Wolfe, RR; Zhang, XJ | 1 |
| Mayatepek, E; Primassin, S; Spiekerkoetter, U; Ter Veld, F | 1 |
| Liu, Z; Mutlib, AE; Talaat, RE; Wang, J | 1 |
| Chace, DH; De Jesús, VR; Hannon, WH; Lim, TH; Mei, JV | 1 |
| Doi, N; Hayashi, M; Tomita, M | 2 |
| Console, L; Giangregorio, N; Indiveri, C; Palmieri, F; Tonazzi, A | 1 |
| Askevold, ET; Aukrust, P; Berge, RK; Bjørndal, B; Dahl, CP; Gullestad, L; Nymoen, SH; Svardal, A; Ueland, T; Øie, E | 1 |
| Doi, N; Hayashi, M; Kimura, A; Tomita, M | 1 |
| Guo, Z; Jensen, MD; Kanaley, JA; Shadid, S; Sheehan, MT | 1 |
| Bakker, BM; Bleeker, A; den Besten, G; Gerding, A; Groen, BK; Houten, SM; Krab, K; Reijngoud, DJ; Simons, SM; Touw, CM; van Eunen, K | 1 |
| Donzelli, M; Haschke, M; Krähenbühl, S; Morand, R | 1 |
| Affolter, A; Clanachan, AS; Gandhi, M; Hersberger, M; Lemieux, H; Lou, PH; Lucchinetti, E; Schaub, MC; Sobhi, HF; Warren, BE; Zaugg, M; Zhang, L | 1 |
| Ando, S; Arai, S; Asaka, I; Higaki, Y; Hitomi, H; Kaneoka, H; Kurose, Y; Nakashima, H; Osafune, K; Saito, T; Sakurai, H; Sudo, M; Tanaka, A; Yamada, K; Yamaguchi, S; Yasuno, T | 1 |
| Danielsen, JH; Dela, F; Dybboe, R; Helge, JW; Larsen, S; Skaaby, S; Søgaard, D; Søndergård, SD; Vigelsoe, A | 1 |
| Antone, U; Cirule, H; Dambrova, M; Grinberga, S; Kuka, J; Liepinsh, E; Makrecka, M; Pugovics, O; Sevostjanovs, E; Volska, K | 1 |
| Deutz, NE; Houten, SM; Schooneman, MG; Soeters, MR; Ten Have, GA; van Vlies, N | 1 |
| Andrew, B; Bezuidenhout, N; George, S; Maarman, G; Madlala, HP; Mendham, A; Ojuka, E; Osiki, PO | 1 |
| Davies, AH; Holmes, E; Lewis, MR; Nicholson, JK; Shalhoub, J; Spagou, K; Vorkas, PA; Want, EJ | 1 |
| Bo, R; Fukuda, S; Hasegawa, Y; Kobayashi, H; Mushimoto, Y; Purevsuren, J; Takahashi, T; Taketani, T; Yamada, K; Yamaguchi, S | 1 |
| Abate, N; Asghar, R; Brasier, AR; Camacho-Hughes, M; Chondronikola, M; Dillon, EL; Durham, WJ; Porter, C; Sheffield-Moore, M; Sidossis, L; Tuvdendorj, D; Volpi, E; Wu, Z; Zhang, X; Zhao, Y | 1 |
| Antone, U; Dambrova, M; Grinberga, S; Kuka, J; Liepinsh, E; Lola, D; Loza, E; Makarova, E; Makrecka-Kuka, M; Sevostjanovs, E; Vilks, K; Vilskersts, R; Volska, K | 1 |
| Bouchouirab, FZ; Carpentier, AC; Dubé, J; Fortin, M; Noll, C | 1 |
| Fujita, N; Matsumoto, M; Miyamoto, T; Nagoshi, N; Nakamura, M; Okada, E; Tsuji, O; Tsuji, T; Watanabe, K; Yagi, M | 1 |
| Kamei, D; Kamei, Y; Mineshima, M; Nitta, K; Tsuchiya, K | 1 |
| Huang, S; Huang, Z; Li, P; Li, Q; Luo, R; Nie, T; Qi, S; Xu, Y; Zhang, Q | 1 |
| Aboulouard, S; Cardon, T; Devos, D; Fournier, I; Kobeissy, F; Mallah, K; Quanico, J; Raffo-Romero, A; Salzet, M; Zibara, K | 1 |
3 review(s) available for carnitine and palmitoylcarnitine
| Article | Year |
|---|---|
Palmitoylcarnitine, a surface-active metabolite.
Topics: Animals; Carnitine; Coenzyme A; Fatty Acids; Humans; Mitochondria; Models, Biological; Palmitoylcarnitine; Subcellular Fractions; Surface-Active Agents | 1996 |
Carnitine system and tumor.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents; Carnitine; Diet; Humans; Neoplasms; Palmitoylcarnitine | 1999 |
Measurement of β-oxidation capacity of biological samples by respirometry: a review of principles and substrates.
Topics: Acyl Coenzyme A; Carnitine; Coenzyme A; Electrodes; Fatty Acids; Feedback, Physiological; Humans; Malates; Mitochondria; Oxidation-Reduction; Oxidative Phosphorylation; Oxygen Consumption; Palmitoylcarnitine | 2016 |
1 trial(s) available for carnitine and palmitoylcarnitine
| Article | Year |
|---|---|
Plasma Palmitoyl-Carnitine (AC16:0) Is a Marker of Increased Postprandial Nonesterified Incomplete Fatty Acid Oxidation Rate in Adults With Type 2 Diabetes.
Topics: Adult; Biomarkers; Carnitine; Diabetes Mellitus, Type 2; Fasting; Fatty Acids, Nonesterified; Female; Humans; Insulin Resistance; Lipid Metabolism; Male; Middle Aged; Oxidation-Reduction; Palmitoylcarnitine; Postprandial Period; Young Adult | 2018 |
162 other study(ies) available for carnitine and palmitoylcarnitine
| Article | Year |
|---|---|
On the capacity of the beta-oxidation of palmitate and palmitoyl-esters in rat liver mitochondria.
Topics: Acyl Coenzyme A; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Carbon Dioxide; Carnitine; Coenzyme A; Male; Mitochondria, Liver; NAD; Oxidation-Reduction; Palmitates; Palmitic Acids; Palmitoyl Coenzyme A; Palmitoyl-CoA Hydrolase; Palmitoylcarnitine; Rats | 1978 |
Effect of clofibrate treatment on acylcarnitine oxidation in isolated rat liver mitochondria.
Topics: Acetoacetates; Acetyl-CoA C-Acetyltransferase; Acetyl-CoA C-Acyltransferase; Acetylcarnitine; Animals; Caprylates; Carnitine; Citrates; Clofibrate; Hydroxybutyrates; Ketone Bodies; Malates; Male; Mitochondria, Liver; Oxidation-Reduction; Oxidoreductases; Oxygen Consumption; Palmitoylcarnitine; Rats | 1979 |
Palmitylcarnitine inhibition of the calcium pump in cardiac sarcoplasmic reticulum: a possible role in myocardial ischemia.
Topics: Animals; Biological Transport, Active; Calcium; Calcium-Transporting ATPases; Carnitine; Coronary Disease; Dogs; In Vitro Techniques; Myocardium; Palmitoylcarnitine; Sarcoplasmic Reticulum; Sodium-Potassium-Exchanging ATPase | 1978 |
In vitro effects of palmitylcarnitine on cardiac plasma membrane Na,K-ATPase, and sarcoplasmic reticulum Ca2+-ATPase and Ca2+ transport.
Topics: Animals; Biological Transport, Active; Calcium; Calcium-Transporting ATPases; Carnitine; Cell Membrane; Dansyl Compounds; Dogs; Heart Ventricles; Kinetics; Myocardium; Palmitoylcarnitine; Sarcoplasmic Reticulum; Sodium-Potassium-Exchanging ATPase; Spectrometry, Fluorescence | 1979 |
Regulation of pyruvate dehydrogenase activity in white adipocyte mitochondria by palmitoyl carnitine and citrate.
Topics: Acyl Coenzyme A; Adipose Tissue; Animals; Carnitine; Citrates; In Vitro Techniques; Male; Mitochondria; NAD; Oxygen Consumption; Palmitoylcarnitine; Pyruvate Dehydrogenase Complex; Rats | 1979 |
Effect of palmitylcarnitine on ouabain binding to Na, K-ATPase.
Topics: Adenosine Triphosphate; Animals; Carnitine; Cattle; Magnesium; Ouabain; Palmitoylcarnitine; Phosphates; Serum Albumin, Bovine; Sheep; Sodium Chloride; Sodium-Potassium-Exchanging ATPase | 1979 |
Familial recurrent rhabdomyolysis due to carnitine palmityl transferase deficiency.
Topics: Acyltransferases; Adult; Animals; Carnitine; Carnitine O-Palmitoyltransferase; Cell Membrane; Humans; Male; Mitochondria, Liver; Mitochondria, Muscle; Myoglobinuria; Palmitoylcarnitine; Rats; Recurrence | 1979 |
Different subcellular localization of palmitoyl-L-carnitine hydrolysis in human and rat liver.
Topics: Animals; Carnitine; Humans; Hydrolysis; Liver; Palmitoylcarnitine; Rats; Species Specificity; Subcellular Fractions | 1979 |
Studies on the effects of saturated and unsaturated short-chain monocarboxylic acids on the energy metabolism of rat liver mitochondria.
Topics: Amino Acids, Branched-Chain; Animals; Carboxylic Acids; Carnitine; Depression, Chemical; Fatty Acids; Fatty Acids, Unsaturated; Glutarates; Mitochondria, Liver; Oxidation-Reduction; Oxygen Consumption; Palmitoylcarnitine; Pyruvates; Rats | 1979 |
The effect of chronic alcohol administration on fatty acid metabolism and pyruvate oxidation of heart mitochondria.
Topics: Acetylcarnitine; Alcoholism; Animals; Carnitine; Carnitine O-Palmitoyltransferase; Fatty Acids; Humans; In Vitro Techniques; Male; Mitochondria, Heart; Oxidation-Reduction; Oxygen Consumption; Palmitoylcarnitine; Pyruvates; Rats | 1977 |
Effects of palmityl coenzyme A and palmitylcarnitine on phosphorylating respiration in heart mitochondria.
Topics: Acyl Coenzyme A; Adenosine Diphosphate; Animals; Carnitine; Dogs; Glutamates; Kinetics; Malates; Mitochondria, Heart; Mitochondrial Swelling; Oxygen Consumption; Palmitoyl Coenzyme A; Palmitoylcarnitine; Rabbits; Succinates | 1978 |
[Induction of mitochondrial volume changes by homologous O-acyl carnitines].
Topics: Animals; Carnitine; Female; Kinetics; Mitochondria; Mitochondria, Liver; Mitochondrial Swelling; Palmitoylcarnitine; Rats; Structure-Activity Relationship | 1978 |
The decreases with age in the activities of enzymes of human skeletal muscle. Some observations on palmityl-carnitine formation, hexokinase activity, and lactate dehydrogenase activity.
Topics: Adolescent; Adult; Aging; Carnitine; Diabetes Mellitus; Female; Hexokinase; Humans; L-Lactate Dehydrogenase; Male; Middle Aged; Muscles; Palmitoylcarnitine | 1978 |
Biochemical and morphological correlates of acute experimental myocardial ischemia in the dog. IV. Energy mechanisms during very early ischemia.
Topics: Acyl Coenzyme A; Acyltransferases; Animals; Carnitine; Carnitine O-Palmitoyltransferase; Citric Acid Cycle; Coronary Disease; Dogs; Glutamates; Glycogen; Mitochondria, Heart; Myocardium; Oxidation-Reduction; Oxygen Consumption; Palmitoyl Coenzyme A; Palmitoylcarnitine; Papillary Muscles; Phosphorylase b; Phosphorylases | 1979 |
The measurement of carnitine and acyl-carnitines: application to the investigation of patients with suspected inherited disorders of mitochondrial fatty acid oxidation.
Topics: Aging; Carnitine; Child, Preschool; Fasting; Fatty Acids; Fatty Acids, Nonesterified; Genetic Diseases, Inborn; Humans; Infant; Mitochondria; Oxidation-Reduction; Palmitoylcarnitine; Perchlorates; Radioligand Assay; Reproducibility of Results; Solubility | 1992 |
Influence of dietary fish oil on mitochondrial function and response to ischemia.
Topics: Animals; Carnitine; Dogs; Electron Transport Complex IV; Fish Oils; Kinetics; Mitochondria, Heart; Myocardial Ischemia; Oxygen Consumption; Palmitoylcarnitine; Phospholipids; Phosphorylation | 1992 |
Changes of hepatic fatty acid metabolism produced by chronic thioacetamide administration in rats.
Topics: Animals; Carnitine; Carnitine O-Palmitoyltransferase; Fatty Acids; Ketone Bodies; Liver; Liver Cirrhosis, Experimental; Male; Malonyl Coenzyme A; Mitochondria, Liver; Oxidation-Reduction; Oxygen; Palmitoyl Coenzyme A; Palmitoylcarnitine; Rats; Rats, Inbred Strains; Thioacetamide; Time Factors | 1992 |
Tissue lipid accumulation by L-aminocarnitine, an inhibitor of carnitine-palmitoyltransferase-2. Studies in intact rats and isolated mitochondria.
Topics: Animals; Betaine; Carnitine; Carnitine O-Palmitoyltransferase; Cholesterol; Female; Lipid Metabolism; Malonyl Coenzyme A; Mitochondria, Liver; Oxidation-Reduction; Palmitoylcarnitine; Phospholipids; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Succinates; Succinic Acid; Triglycerides | 1992 |
The effects of novel vasodilator long chain acyl carnitine esters in the isolated perfused heart of the rat.
Topics: Animals; Benzopyrans; Carnitine; Coronary Circulation; Cromakalim; Dose-Response Relationship, Drug; Epoprostenol; Heart; Iloprost; In Vitro Techniques; Male; Myocardial Contraction; Nitrates; Palmitoylcarnitine; Pentanols; Pyrroles; Rats; Rats, Inbred Strains; Vasodilator Agents; Verapamil | 1990 |
Interactions of palmitoyl carnitine with the endothelium in rat aorta.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Adenosine Triphosphate; Animals; Aorta, Thoracic; Calcimycin; Carbachol; Carnitine; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Palmitoylcarnitine; Phenylephrine; Potassium; Rats; Rats, Inbred Strains | 1990 |
Protein binding of L-carnitine family components.
Topics: Acetylcarnitine; Animals; Blood Proteins; Carnitine; Chromatography, Gel; Dogs; Humans; Palmitoylcarnitine; Protein Binding; Rats; Serum Albumin; Ultrafiltration | 1991 |
Regulation of fatty acid beta-oxidation in rat heart mitochondria.
Topics: 3-Hydroxyacyl CoA Dehydrogenases; Acetyl Coenzyme A; Acetyl-CoA C-Acyltransferase; Animals; Carnitine; Coenzyme A; Fatty Acids; In Vitro Techniques; Mitochondria, Heart; NAD; Oxaloacetates; Oxidation-Reduction; Oxygen Consumption; Palmitoylcarnitine; Rats | 1991 |
Synthesis and purification of radioactive fatty acylcarnitines of high specific activity.
Topics: 1-Propanol; Carnitine; Chemistry Techniques, Analytical; Chromatography, Ion Exchange; Heptanes; Hydrochloric Acid; Palmitoylcarnitine; Tritium | 1991 |
Biosynthesis of phosphatidic acid by glycerophosphate acyltransferases in rat liver mitochondria and microsomes.
Topics: Acylation; Animals; Carnitine; Cations, Divalent; Detergents; Glycerol-3-Phosphate O-Acyltransferase; Glycerophosphates; Membrane Proteins; Microsomes, Liver; Mitochondria, Liver; Palmitoyl Coenzyme A; Palmitoylcarnitine; Phosphatidic Acids; Rats | 1990 |
Regulation of canine myocardial lysophospholipase.
Topics: Animals; Carnitine; Coronary Disease; Cytosol; Dogs; Female; Heart; Lysophospholipase; Male; Microsomes, Liver; Myocardium; Palmitoylcarnitine; Phosphatidylcholines | 1990 |
Palmitoyl carnitine can exist in lamellar and hexagonal phases.
Topics: Buffers; Carnitine; Chemical Phenomena; Chemistry, Physical; Lipid Bilayers; Micelles; Molecular Structure; Palmitoylcarnitine; Temperature | 1990 |
Electrophysiological effects of L-palmitoylcarnitine in single ventricular myocytes.
Topics: Animals; Calcium; Carnitine; Cell Separation; Electrophysiology; Heart; Heart Ventricles; Membrane Potentials; Myocardium; Neuraminidase; Osmolar Concentration; Palmitoylcarnitine; Ryanodine; Time Factors | 1990 |
Effect of palmitoyl-DL-carnitine on the 3H-dihydroergotoxine intestinal absorption in rat.
Topics: Animals; Bile; Carnitine; Chromatography, High Pressure Liquid; Dihydroergotoxine; Female; Gastric Mucosa; Intestinal Absorption; Palmitoylcarnitine; Rats; Rats, Inbred Strains; Stomach; Theophylline | 1990 |
Direct activation of Ca2+ channels by palmitoyl carnitine, a putative endogenous ligand.
Topics: Animals; Binding, Competitive; Calcium Channel Blockers; Carnitine; Cerebral Cortex; Detergents; Guinea Pigs; In Vitro Techniques; Ion Channels; Male; Membranes; Muscle, Smooth; Palmitoylcarnitine; Rats; Rats, Inbred Strains; Verapamil | 1987 |
Synergistic effect of palmitoylcarnitine and the ionophore A23187 on isolated rat mast cells.
Topics: Animals; Calcimycin; Carnitine; Drug Synergism; Histamine Release; Male; Mast Cells; Palmitoylcarnitine; Phloretin; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1988 |
Interaction of palmitoyl carnitine with calcium antagonists in myocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Carnitine; Cells, Cultured; Chick Embryo; Heart; Lysophosphatidylcholines; Myocardial Contraction; Myocardium; Palmitoylcarnitine | 1989 |
Palmitoyl-L-carnitine increases the release of prostacyclin from vascular endothelial cells.
Topics: Animals; Carnitine; Cattle; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Epoprostenol; Palmitoylcarnitine; Platelet Activation | 1989 |
Effects of long-chain acyl carnitine on membrane fluidity of human erythrocytes.
Topics: Acetylcarnitine; Adult; Calcium Chloride; Carnitine; Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Humans; Membrane Fluidity; Palmitoylcarnitine | 1989 |
Effects of L-carnitine and palmitoylcarnitine on membrane fluidity of human erythrocytes.
Topics: Carnitine; Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Humans; Kinetics; Membrane Fluidity; Microscopy, Electron, Scanning; Palmitoylcarnitine | 1989 |
Mechanism of arrhythmias induced by palmitylcarnitine in guinea pig papillary muscle.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Carnitine; Guinea Pigs; In Vitro Techniques; Myocardial Contraction; Palmitoylcarnitine; Papillary Muscles | 1989 |
Effects of l-carnitine on membrane potential derangements induced by palmitoylcarnitine and anoxia in isolated superfused guinea-pig papillary muscle.
Topics: Animals; Carnitine; Cell Hypoxia; Electrophysiology; Guinea Pigs; Heart; In Vitro Techniques; Male; Membrane Potentials; Palmitoylcarnitine; Papillary Muscles | 1989 |
Nonmediated flip-flop of phospholipid analogues in the erythrocyte membrane as probed by palmitoylcarnitine: basic properties and influence of membrane modification.
Topics: Adenosine Triphosphate; Animals; Biological Transport; Carnitine; Cattle; Erythrocyte Membrane; Hot Temperature; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Lipid Bilayers; Molecular Probes; Palmitoylcarnitine; Phospholipids; Protein Denaturation; Spectrin | 1989 |
Metabolism of octanoyl- and palmitoylcarnitine by intact rat hepatocytes.
Topics: Animals; Carnitine; In Vitro Techniques; Ketone Bodies; Liver; Male; Palmitoylcarnitine; Rats; Rats, Inbred Strains | 1989 |
Increased cellular internalization of amphiphiles in a multidrug-resistant CHO cell line.
Topics: Animals; Biological Transport; Carnitine; Cell Line; Cell Membrane; Cricetinae; Cyclosporins; Diffusion; Drug Resistance; Kinetics; Lysophosphatidylcholines; Palmitoylcarnitine; Quinacrine; Solubility; Verapamil | 1989 |
Long-chain acylcarnitines mediate the hypoxia-induced increase in alpha 1-adrenergic receptors on adult canine myocytes.
Topics: Adenosine Triphosphate; Animals; Carnitine; Carnitine O-Palmitoyltransferase; Cell Survival; Creatine Kinase; Dogs; Electrophysiology; Epoxy Compounds; Hypoxia; Kinetics; L-Lactate Dehydrogenase; Myocardium; Palmitoylcarnitine; Phosphocreatine; Prazosin; Receptors, Adrenergic, alpha | 1987 |
Relationship between the electrochemical proton gradient and respiration: pyruvate and l-palmitoylcarnitine as hydrogen donors for rat heart mitochondria.
Topics: Animals; Carnitine; Electrochemistry; Energy Metabolism; Female; In Vitro Techniques; Membrane Potentials; Mitochondria, Heart; Oxygen Consumption; Palmitoylcarnitine; Protons; Pyruvates; Pyruvic Acid; Rats | 1987 |
Acylcarnitines: drug absorption-enhancing agents in the gastrointestinal tract.
Topics: Animals; Carnitine; Cefoxitin; Cytarabine; Dogs; Female; Gentamicins; Intestinal Absorption; Intestinal Mucosa; Male; Methyldopa; Microscopy, Electron; Palmitoylcarnitine; Pharmaceutical Preparations; Rats; Rats, Inbred Strains; Rectum; Somatostatin | 1986 |
Palmitoyl carnitine: an endogenous promotor of calcium efflux from rat heart mitochondria.
Topics: Animals; Calcium; Carnitine; Female; Glutamates; Glutamic Acid; Malates; Mitochondria, Heart; NAD; Oxidation-Reduction; Palmitoylcarnitine; Rats; Rats, Inbred Strains; Succinates; Succinic Acid | 1988 |
Inhibition of sarcolemmal Na+-K+-ATPase by palmitoyl carnitine: potentiation by propranolol.
Topics: Alamethicin; Animals; Carnitine; Dogs; Drug Synergism; Myocardium; Palmitoylcarnitine; Polidocanol; Polyethylene Glycols; Propranolol; Sarcolemma; Serum Albumin, Bovine; Sodium-Potassium-Exchanging ATPase | 1985 |
Regulation of palmitoylcarnitine oxidation in isolated rat liver mitochondria. Role of the redox state of NAD(H).
Topics: Acetoacetates; Acetyl Coenzyme A; Acyl Coenzyme A; Adenosine Diphosphate; Animals; Carnitine; Cytochrome c Group; Fluorometry; Male; Malonates; Mitochondria, Liver; Models, Biological; NAD; NADP; Oxidation-Reduction; Palmitoylcarnitine; Rats; Rats, Inbred Strains; Rotenone | 1986 |
Separation of acylcarnitines from biological samples using high-performance liquid chromatography.
Topics: Animals; Carnitine; Chemical Fractionation; Chromatography, High Pressure Liquid; Fasting; Liver; Male; Palmitoylcarnitine; Perchlorates; Rats; Rats, Inbred Strains | 1986 |
Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion and epidermal ornithine decarboxylase activity in mouse skin by palmitoylcarnitine.
Topics: Animals; Calcium; Carnitine; Dose-Response Relationship, Drug; Egtazic Acid; Female; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Palmitoylcarnitine; Phorbols; Protein Kinase C; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1986 |
Inhibition of epidermal growth factor binding in rat pancreatic acini by palmitoyl carnitine: evidence for Ca2+ and protein kinase C independent regulation.
Topics: Animals; Calcimycin; Calcium; Carnitine; Epidermal Growth Factor; ErbB Receptors; In Vitro Techniques; Kinetics; Male; Palmitoylcarnitine; Pancreas; Protein Kinase C; Rats; Rats, Inbred Strains | 1987 |
Carnitine-acylcarnitine translocase in ischemia: evidence for sulfhydryl modification.
Topics: Animals; Biological Transport; Carnitine; Carnitine Acyltransferases; Carnitine O-Palmitoyltransferase; Coronary Circulation; Coronary Disease; Dithiothreitol; Dogs; Glutathione; Glutathione Disulfide; Ischemia; Kinetics; Oxidation-Reduction; Oxygen Consumption; Palmitoylcarnitine; Sulfhydryl Compounds; Transferases | 1987 |
Oxidation of acetoacetate and palmitylcarnitine by brain and liver mitochondria from suckling and adult rats.
Topics: Acetoacetates; Acetylcarnitine; Animals; Animals, Suckling; Brain; Carnitine; In Vitro Techniques; Malates; Mitochondria; Mitochondria, Liver; Oxidation-Reduction; Palmitoylcarnitine; Rats; Rats, Inbred Strains; Succinates | 1985 |
Modulation by palmitoyl-carnitine of calcium activated, phospholipid-dependent protein kinase activity and inhibition of melanoma cell growth.
Topics: Adult; Carnitine; Cell Survival; Cytosol; Humans; Male; Melanoma; Palmitoylcarnitine; Protein Kinase C; Tumor Stem Cell Assay | 1988 |
Skeletal muscle mitochondrial beta-oxidation. A study of the products of oxidation of [U-14C]hexadecanoate by h.p.l.c. using continuous on-line radiochemical detection.
Topics: Acetylcarnitine; Animals; Carbon Radioisotopes; Carnitine; Chromatography, High Pressure Liquid; Malates; Male; Mitochondria, Muscle; Oxidation-Reduction; Palmitic Acids; Palmitoylcarnitine; Rats; Rats, Inbred Strains; Tissue Distribution | 1988 |
Hemipalmitoylcarnitinium, a strong competitive inhibitor of purified hepatic carnitine palmitoyltransferase.
Topics: Acyltransferases; Animals; Binding, Competitive; Carnitine; Carnitine O-Acetyltransferase; Carnitine O-Palmitoyltransferase; Choline; Kinetics; Liver; Palmitoyl Coenzyme A; Palmitoylcarnitine; Rats | 1988 |
Exogenous palmitoyl carnitine and membrane damage in rat hearts.
Topics: Animals; Calcium; Carnitine; Cell Membrane; Heart; Male; Myocardium; Myoglobin; Palmitoylcarnitine; Rats; Rats, Inbred Strains; Sarcolemma | 1988 |
Calcium ions and 1-palmitoyl carnitine reduce erythrocyte electrophoretic mobility: test of a surface charge hypothesis.
Topics: Calcium; Carnitine; Cell Movement; Erythrocyte Membrane; Erythrocytes; Hemolysis; Humans; Membrane Potentials; Membrane Proteins; Neuraminidase; Palmitic Acids; Palmitoylcarnitine; Surface Properties | 1988 |
Effects of L-propionylcarnitine on electrical and mechanical alterations induced by amphiphilic lipids in isolated guinea pig ventricular muscle.
Topics: Animals; Carnitine; Electrophysiology; Female; Guinea Pigs; Lysophosphatidylcholines; Male; Microscopy, Electron; Myocardial Contraction; Myocardium; Palmitoylcarnitine; Papillary Muscles | 1988 |
Inhibition of gap junctional blockage by palmitoyl carnitine and TMB-8 in a rat liver epithelial cell line.
Topics: Animals; Carnitine; Cell Communication; Cell Line; Coloring Agents; Epithelium; Gallic Acid; Intercellular Junctions; Liver; Palmitoylcarnitine; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1988 |
Palmitoylcarnitine reverses 12-O-tetradecanoylphorbol-13-acetate-induced refractory state for the TPA-caused ornithine decarboxylase induction in mouse epidermis.
Topics: Animals; Carnitine; Enzyme Induction; Female; Kinetics; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Palmitoylcarnitine; Protein Kinase C; Skin; Tetradecanoylphorbol Acetate | 1988 |
Inhibition of hepatic fatty acid oxidation at carnitine palmitoyltransferase I by the peroxisome proliferator 2-hydroxy-3-propyl-4-[6-(tetrazol-5-yl) hexyloxy]acetophenone.
Topics: Acetophenones; Acyltransferases; Animals; Azoles; Caprylates; Carnitine; Carnitine O-Palmitoyltransferase; Fatty Acids; In Vitro Techniques; Isoenzymes; Ketone Bodies; Liver; Male; Microbodies; Oleic Acid; Oleic Acids; Oxidation-Reduction; Palmitoyl Coenzyme A; Palmitoylcarnitine; Rats; Rats, Inbred F344; Tetrazoles | 1988 |
Differential effects of L-propionylcarnitine on the electrical and mechanical properties of guinea pig ventricular muscle in normal and acidic conditions.
Topics: Action Potentials; Animals; Carnitine; Guinea Pigs; Hydrogen-Ion Concentration; Myocardial Contraction; Palmitoylcarnitine; Papillary Muscles | 1987 |
Modulation by palmitoylcarnitine of protein kinase C activation.
Topics: Animals; Calcium; Carnitine; Diglycerides; Enzyme Activation; Histones; Mice; Palmitoylcarnitine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phospholipids; Protein Kinase C | 1987 |
Characterization of hepatic carnitine palmitoyltransferase. Use of bromoacyl derivatives and antibodies.
Topics: Acyl Coenzyme A; Acyltransferases; Animals; Antibodies; Carnitine; Carnitine O-Palmitoyltransferase; Detergents; Kinetics; Liposomes; Mitochondria, Liver; Octoxynol; Palmitoyl Coenzyme A; Palmitoylcarnitine; Polyethylene Glycols; Rats; Rats, Inbred Strains; Sonication | 1987 |
On the possible role of long chain fatty acylcarnitine accumulation in producing functional and calcium permeability changes in membranes during myocardial ischaemia.
Topics: Acetylcarnitine; Animals; Calcium; Carnitine; Cell Membrane Permeability; Coronary Disease; Myocardium; Palmitoylcarnitine; Sarcolemma; Swine | 1987 |
The effects of ischaemia, lysophosphatidylcholine and palmitoylcarnitine on rat heart phospholipase A2 activity.
Topics: Animals; Carnitine; Coronary Disease; In Vitro Techniques; Lysophosphatidylcholines; Male; Myocardium; Palmitoylcarnitine; Perfusion; Phospholipases; Phospholipases A; Phospholipases A2; Rats; Rats, Inbred Strains | 1987 |
Aggregation of submitochondrial particles by heparin and its application to the study of carnitine transport.
Topics: Animals; Biological Transport; Carnitine; Cattle; Cell Fractionation; Heparin; Mitochondria, Heart; Palmitoylcarnitine; Submitochondrial Particles | 1986 |
A new inhibitor of the long-chain fatty acid transfer across the mitochondrial membrane: 2-(3-methylcinnamylhydrazono)-propionate (BM 42.304).
Topics: Acyltransferases; Animals; Biological Transport; Carnitine; Carnitine Acyltransferases; Carnitine O-Palmitoyltransferase; Cinnamates; Epoxy Compounds; Fatty Acids; Guinea Pigs; Hypoglycemic Agents; Intracellular Membranes; Kinetics; Male; Malonyl Coenzyme A; Mitochondria, Liver; Palmitoylcarnitine; Transferases | 1985 |
Transfer and metabolism of carnitine and carnitine esters in the in vitro perfused human placenta.
Topics: Acetylcarnitine; Carnitine; Esters; Female; Glucose; Humans; In Vitro Techniques; Lactates; Lysine; Maternal-Fetal Exchange; Palmitoylcarnitine; Perfusion; Placenta; Pregnancy; Pyruvates | 1985 |
Protection by acyl-carnitines and phenylmethylsulfonyl fluoride of rat heart subjected to ischemia and reperfusion.
Topics: Animals; Calcium; Carnitine; Cell Membrane; Coronary Disease; Cytosol; Glycogen Synthase; L-Lactate Dehydrogenase; Male; Myocardial Contraction; Myoglobin; Palmitoylcarnitine; Perfusion; Phenylmethylsulfonyl Fluoride; Phosphorylases; Rats; Sulfones | 1985 |
Mitochondrial Ca2+ fluxes: role of free fatty acids, acyl-CoA and acylcarnitine.
Topics: Acyl Coenzyme A; Animals; Biological Transport, Active; Calcium; Carnitine; Kinetics; Linoleic Acid; Linoleic Acids; Male; Mitochondria, Heart; Oxygen Consumption; Palmitic Acid; Palmitic Acids; Palmitoyl Coenzyme A; Palmitoylcarnitine; Rats; Rats, Inbred Strains; Serum Albumin, Bovine | 1986 |
Inhibition of palmitoylcarnitine oxidation by pyruvate in rat heart mitochondria.
Topics: Animals; Biological Transport; Carnitine; Coumaric Acids; Diabetes Mellitus, Experimental; Dichloroacetic Acid; In Vitro Techniques; Mitochondria, Heart; Oxidation-Reduction; Palmitoylcarnitine; Pyruvate Dehydrogenase Complex; Pyruvates; Rats; Uncoupling Agents | 1985 |
A fixation procedure suitable for autoradiography of endogenous long-chain acyl carnitine.
Topics: Animals; Autoradiography; Carnitine; Cells, Cultured; Histocytochemistry; Myocardium; Palmitoylcarnitine; Rats | 1985 |
Effects of the mode of addition of acyl-CoA on the initial rate of formation of acylcarnitine in the presence of carnitine by intact rat liver mitochondria in vitro.
Topics: Acyl Coenzyme A; Albumins; Animals; Carnitine; Female; In Vitro Techniques; Mitochondria, Liver; Palmitoyl Coenzyme A; Palmitoylcarnitine; Rats; Rats, Inbred Strains; Time Factors | 1985 |
Inhibitory effects of some long-chain unsaturated fatty acids on mitochondrial beta-oxidation. Effects of streptozotocin-induced diabetes on mitochondrial beta-oxidation of polyunsaturated fatty acids.
Topics: Animals; Carnitine; Diabetes Mellitus, Experimental; Fatty Acids, Unsaturated; Male; Mitochondria, Liver; Oxidation-Reduction; Oxygen Consumption; Palmitoylcarnitine; Rats; Valinomycin | 1985 |
Effect of l-carnitine chloride and its acetyl derivative on the electrophysiological derangement induced by palmityl-l-carnitine in isolated canine ventricular muscle.
Topics: Acetylcarnitine; Animals; Carnitine; Disopyramide; Dogs; Female; Heart; In Vitro Techniques; Male; Membrane Potentials; Palmitoylcarnitine | 1985 |
Effects of palmitoyl carnitine and LPC on cardiac sarcolemmal Na+-K+-ATPase.
Topics: Animals; Carnitine; Dogs; Lysophosphatidylcholines; Myocardium; Palmitoylcarnitine; Sarcolemma; Sodium Dodecyl Sulfate; Sodium-Potassium-Exchanging ATPase | 1984 |
Respiration-dependent calcium ion uptake by two preparations of cardiac mitochondria. Effects of palmitoyl-coenzyme A and palmitoylcarnitine on calcium ion cycling and nicotinamide nucleotide reduction state.
Topics: Acyl Coenzyme A; Animals; Calcium; Carnitine; Cell Fractionation; Dogs; In Vitro Techniques; Kinetics; Mitochondria, Heart; NAD; NADP; Oxidation-Reduction; Palmitoyl Coenzyme A; Palmitoylcarnitine; Ruthenium Red | 1980 |
Differential regulation of calcium-dependent and calcium-independent cyclic nucleotide phosphodiesterases from heart by palmitoylcarnitine and palmitoyl coenzyme A.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Acyl Coenzyme A; Animals; Calcium; Carnitine; Cattle; Isoenzymes; Kinetics; Myocardium; Palmitoyl Coenzyme A; Palmitoylcarnitine; Structure-Activity Relationship; Trifluoperazine | 1982 |
L-palmitylcarnitine and calcium ions act similarly on excitatory ionic currents in avian ventricular muscle.
Topics: Action Potentials; Animals; Calcium; Carnitine; Chickens; Female; Ion Channels; Male; Myocardial Contraction; Palmitoylcarnitine; Sodium; Ventricular Function | 1983 |
Inhibition by palmitoylcarnitine of adhesion and morphological changes in HL-60 cells induced by 12-O-tetradecanoylphorbol-13-acetate.
Topics: Caenorhabditis elegans Proteins; Carnitine; Carrier Proteins; Cell Adhesion; Cell Line; Drug Antagonism; Humans; Kinetics; Leukemia, Myeloid, Acute; Palmitoylcarnitine; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1984 |
Effect of palmitoyl carnitine on Na+, K+-ATPase and adenylate cyclase activity of canine myocardial sarcolemma.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Carnitine; Dogs; Myocardium; Palmitoylcarnitine; Sarcolemma; Sodium-Potassium-Exchanging ATPase | 1984 |
The effect of lipid intermediates on Ca2+ and Na+ permeability and (Na+ + K+)-ATPase of cardiac sarcolemma. A possible role in myocardial ischemia.
Topics: Animals; Calcimycin; Calcium; Carnitine; Cell Membrane Permeability; Coronary Disease; Fatty Acids; Myocardium; Palmitoylcarnitine; Protein Kinases; Sarcolemma; Sodium; Sodium-Potassium-Exchanging ATPase; Swine | 1984 |
Mechanism of carnitine acylcarnitine translocase-catalyzed import of acylcarnitines into mitochondria.
Topics: Acetylcarnitine; Animals; Betaine; Biological Transport; Carnitine; Carnitine Acyltransferases; Ethylmaleimide; Kinetics; Mersalyl; Mitochondria, Heart; Mitochondria, Liver; Palmitoylcarnitine; Rats; Structure-Activity Relationship; Surface-Active Agents; Temperature; Transferases; Tritium | 1984 |
Purification and characterization of mitochondrial thioesterase from rabbit myocardium and its inhibition by palmitoyl carnitine.
Topics: Animals; Calcium Chloride; Carnitine; Kinetics; Magnesium; Magnesium Chloride; Mitochondria, Heart; Molecular Weight; NAD; Palmitoylcarnitine; Rabbits; Substrate Specificity; Thiolester Hydrolases | 1984 |
Carnitine ester hydrolysis in arteries from normal and cholesterol-fed rabbits and the effects of carnitine esters on arterial microsomal ACAT.
Topics: Animals; Aorta, Thoracic; Carnitine; Cholesterol, Dietary; Hydrolysis; Kinetics; Male; Microsomes; Palmitoylcarnitine; Rabbits; Sterol O-Acyltransferase | 1984 |
Sources of error in determinations of carnitine and acylcarnitine in plasma.
Topics: Acetylcarnitine; Animals; Carnitine; Chromatography, Thin Layer; False Negative Reactions; Humans; Palmitoylcarnitine; Sheep | 1984 |
Cytosolic lysophospholipase in cardiac myocytes and its inhibition by L-palmitoyl carnitine.
Topics: Animals; Carnitine; Chemical Phenomena; Chemistry; Cytosol; Lysophospholipase; Myocardium; Palmitoylcarnitine; Phospholipases; Rabbits; Rats | 1984 |
Mitochondria from the hepatopancreas of the marine clam Mercenaria mercenaria: substrate preferences and salt and pH effects on the oxidation of palmitoyl-L-carnitine and succinate.
Topics: Animals; Bivalvia; Carnitine; Citric Acid Cycle; Hydrogen-Ion Concentration; Liver; Mitochondria; Osmolar Concentration; Oxidation-Reduction; Palmitoylcarnitine; Pancreas; Potassium Chloride; Substrate Specificity; Succinates; Succinic Acid | 1984 |
Oxidation and ketogenesis in hepatocytes of lean and obese Zucker rats.
Topics: Animals; Carbon Dioxide; Carnitine; Fasting; Female; Food; Glucagon; Glucose; Ketone Bodies; Liver; Obesity; Oxidation-Reduction; Palmitates; Palmitoylcarnitine; Rats; Rats, Zucker | 1982 |
Rabbit myocardial cytosolic lysophospholipase. Purification, characterization, and competitive inhibition by L-palmitoyl carnitine.
Topics: Animals; Carnitine; Hot Temperature; Kinetics; Lysophospholipase; Myocardium; Palmitoylcarnitine; Phospholipases; Rabbits; Substrate Specificity | 1983 |
Modes of inhibition by acylcarnitines, adriamycin and trifluoperazine of cardiac phospholipid-sensitive calcium-dependent protein kinase.
Topics: Animals; Binding, Competitive; Calcium; Carnitine; Cattle; Diglycerides; Dose-Response Relationship, Drug; Doxorubicin; Drug Interactions; Myocardium; Palmitoylcarnitine; Phospholipids; Protein Kinase Inhibitors; Trifluoperazine | 1983 |
Plasma and liver carnitine (free and esterified) levels and their interrelationships in moderately hypercholesterolemic monkeys (Macaca arctoides).
Topics: 3-Hydroxybutyric Acid; Acetylcarnitine; Animals; Carnitine; Hydroxybutyrates; Hypercholesterolemia; Liver; Macaca; Male; Palmitoylcarnitine | 1983 |
The effect of alloxan- and streptozotocin-induced diabetes on calcium transport in rat cardiac sarcoplasmic reticulum. The possible involvement of long chain acylcarnitines.
Topics: Animals; Biological Transport; Calcium; Carnitine; Diabetes Mellitus, Experimental; Female; Myocardium; Palmitoylcarnitine; Rats; Rats, Inbred Strains; Sarcoplasmic Reticulum | 1983 |
Substrate proteins for calmodulin-sensitive and phospholipid-sensitive Ca2+-dependent protein kinases in heart, and inhibition of their phosphorylation by palmitoylcarnitine.
Topics: Animals; Calcium; Calmodulin; Carnitine; Doxorubicin; Guinea Pigs; Molecular Weight; Myocardium; Palmitoylcarnitine; Phospholipids; Protein Kinase Inhibitors; Protein Kinases; Substrate Specificity | 1981 |
Effects of L-carnitine on action potential or canine papillary muscle impaired by long chain acyl carnitine.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Carnitine; Dogs; Fatty Acids, Nonesterified; In Vitro Techniques; Palmitoylcarnitine; Papillary Muscles | 1982 |
The effect of excess (acyl) carnitine on lipid metabolism in rat heart.
Topics: Animals; Carnitine; Fat Emulsions, Intravenous; Fatty Acids; Glycerol-3-Phosphate O-Acyltransferase; Hydrogen-Ion Concentration; Hydrolysis; Lipid Metabolism; Lipoprotein Lipase; Myocardium; Oxidation-Reduction; Palmitoylcarnitine; Rats; Triglycerides; Triolein | 1982 |
Effects of palmitic acid and palmityl carnitine on calcium sequestration by rabbit skeletal sarcoplasmic reticulum vesicles.
Topics: Animals; Calcium; Carnitine; Dose-Response Relationship, Drug; Muscles; Myocardial Contraction; Palmitic Acid; Palmitic Acids; Palmitoylcarnitine; Rabbits; Sarcoplasmic Reticulum | 1982 |
Uneven distribution of palmitoyl carnitine in solutions because of migration to air/water interphase.
Topics: Air; Carnitine; Chemical Phenomena; Chemistry, Physical; Palmitoylcarnitine; Solutions; Temperature; Water | 1981 |
Phosphoenolpyruvate synthesis by fetal guinea-pig liver mitochondria.
Topics: Animals; Animals, Newborn; Caprylates; Carnitine; Guinea Pigs; Ketoglutaric Acids; Malates; Mitochondria, Liver; Palmitoylcarnitine; Phosphoenolpyruvate; Succinates | 1981 |
Electrophysiological effects of amphiphiles on canine purkinje fibers. Implications for dysrhythmia secondary to ischemia.
Topics: Acidosis; Animals; Arrhythmias, Cardiac; Carnitine; Coronary Disease; Dogs; Electrophysiology; Fatty Acids, Nonesterified; Glycerylphosphorylcholine; Heart Conduction System; Liposomes; Lysophosphatidylcholines; Palmitoylcarnitine; Purkinje Fibers; Surface-Active Agents | 1981 |
Inhibition of myocardial lysophosphatidyl choline transacylase by palmitoyl carnitine: implications for arrhythmogenesis.
Topics: 1-Acylglycerophosphocholine O-Acyltransferase; Acyltransferases; Animals; Arrhythmias, Cardiac; Carnitine; Coronary Disease; In Vitro Techniques; Myocardium; Palmitoylcarnitine; Phosphatidylcholines; Rabbits | 1981 |
Effect of carnitine on mitochondrial oxidation of palmitoylearnitine.
Topics: Acetoacetates; Acetylcarnitine; Animals; Carnitine; Citrates; Coenzyme A; In Vitro Techniques; Malates; Malonates; Mitochondria, Liver; Oxidation-Reduction; Oxygen Consumption; Palmitoylcarnitine; Rats | 1980 |
Fatty acid metabolism in skeletal muscle mitochondria from two strains of dystrophic mice.
Topics: Acetylcarnitine; Animals; Carnitine; Carnitine O-Acetyltransferase; Carnitine O-Palmitoyltransferase; Citrate (si)-Synthase; Coenzyme A; Disease Models, Animal; Flavoproteins; Malates; Mice; Mice, Mutant Strains; Mitochondria, Muscle; Muscular Dystrophy, Animal; Palmitoylcarnitine | 1980 |
Modulation of alpha 1-adrenoceptors in rat left ventricle by ischaemia and acyl carnitines: protection by ranolazine.
Topics: Acetanilides; Animals; Carnitine; Carnitine O-Palmitoyltransferase; Dihydroalprenolol; Dihydropyridines; In Vitro Techniques; Male; Myocardial Ischemia; Palmitoylcarnitine; Piperazines; Ranolazine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha | 1993 |
Insulin receptor autophosphorylation and signaling is altered by modulation of membrane physical properties.
Topics: 3T3 Cells; Animals; Apolipoprotein A-I; Biophysical Phenomena; Biophysics; Carnitine; Cell Membrane; Dipeptides; Glucose; Insulin; Laurates; Lipid Bilayers; Lysophosphatidylcholines; Mice; Palmitoylcarnitine; Phosphorylation; Receptor, Insulin; Signal Transduction; Sphingosine; Temperature | 1995 |
Toxicity of cephalosporins to fatty acid metabolism in rabbit renal cortical mitochondria.
Topics: Animals; Butyrates; Butyric Acid; Carnitine; Cephalexin; Cephaloglycin; Cephaloridine; Cephalosporins; Fatty Acids; Kidney Cortex; Mitochondria; Palmitoylcarnitine; Rabbits | 1995 |
Activation of the Ca2+ release channel of skeletal muscle sarcoplasmic reticulum by palmitoyl carnitine.
Topics: Animals; Calcium; Calcium Channels; Calcium Radioisotopes; Carnitine; Ion Channel Gating; Kinetics; Muscles; Palmitic Acid; Palmitic Acids; Palmitoylcarnitine; Probability; Rabbits; Radioisotope Dilution Technique; Ryanodine; Sarcoplasmic Reticulum; Swine; Tritium | 1993 |
Relationships between the effects of superoxide anion and palmitoyl-L-carnitine on the Ca(2+)-ATPase of vascular smooth muscle sarcoplasmic reticulum.
Topics: Animals; Antioxidants; Calcium-Transporting ATPases; Carnitine; Cattle; Cysteine; Dose-Response Relationship, Drug; Free Radicals; Hypoxanthine; Hypoxanthines; Muscle, Smooth, Vascular; Oxidation-Reduction; Oxygen; Palmitoylcarnitine; Sarcoplasmic Reticulum; Superoxides; Xanthine Oxidase | 1993 |
Acetylcarnitine increases membrane cytoskeletal protein-protein interactions.
Topics: Acetylcarnitine; Alzheimer Disease; Carnitine; Cytoskeletal Proteins; Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Humans; In Vitro Techniques; Membrane Lipids; Palmitoylcarnitine | 1993 |
Effects of L-carnitine and its acetate and propionate esters on the molecular dynamics of human erythrocyte membrane.
Topics: Acetylcarnitine; Carnitine; Diphenylhexatriene; Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Esters; Humans; Membrane Fluidity; Membrane Proteins; Palmitoylcarnitine; Pyrimidinones; Spin Labels | 1993 |
(+)-Hemipalmitoylcarnitinium strongly inhibits carnitine palmitoyltransferase-I in intact mitochondria.
Topics: Animals; Binding, Competitive; Carnitine; Carnitine O-Palmitoyltransferase; Heart; Liver; Male; Mitochondria; Myocardium; Palmitoylcarnitine; Rats; Rats, Sprague-Dawley | 1993 |
High performance liquid chromatography of long-chain acylcarnitine and phospholipids in fatty acid turnover studies.
Topics: Carnitine; Chromatography, High Pressure Liquid; Deoxyglucose; Epoxy Compounds; Erythrocytes; Fatty Acids; Humans; Membrane Lipids; Palmitic Acid; Palmitoylcarnitine; Phospholipids; Ultraviolet Rays | 1996 |
On the roles of long-chain acyl carnitine accumulation and impaired glucose utilization in ischaemic contracture development and tissue damage in the guinea-pig heart.
Topics: Animals; Calcium; Carnitine; Cells, Cultured; Chick Embryo; Dose-Response Relationship, Drug; Female; Glucose; Guinea Pigs; Heart; In Vitro Techniques; Kinetics; Myocardial Contraction; Myocardial Ischemia; Myocardium; Palmitic Acid; Palmitic Acids; Palmitoylcarnitine; Papillary Muscles; Perfusion; Serum Albumin; Time Factors | 1996 |
Potentiation of human polymorphonuclear leukocyte activation by atrial natriuretic peptide. Inhibitory effect of carnitine congeners.
Topics: Atrial Natriuretic Factor; Carnitine; Cell Adhesion; Cell Membrane; Drug Synergism; Enzyme Inhibitors; Gene Expression Regulation; Humans; Hydrogen Peroxide; L-Selectin; Leukotriene B4; Macrophage-1 Antigen; Myocardial Reperfusion Injury; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Palmitoylcarnitine; Protein Kinase C; Reactive Oxygen Species; Staurosporine | 1996 |
Stimulation of carnitine acylcarnitine translocase activity in heart mitochondria from hyperthyroid rats.
Topics: Animals; Cardiolipins; Carnitine; Carnitine Acyltransferases; Fatty Acids; Hyperthyroidism; Male; Mitochondria, Heart; Oxidation-Reduction; Oxygen Consumption; Palmitoylcarnitine; Rats; Rats, Wistar | 1996 |
Broad specificity of carnitine palmitoyltransferase II towards long-chain acyl-CoA beta-oxidation intermediates and its practical approach to the synthesis of various long-chain acylcarnitines.
Topics: Acyl Coenzyme A; Carnitine; Carnitine O-Palmitoyltransferase; Humans; Oxidation-Reduction; Palmitoylcarnitine; Spectrometry, Mass, Fast Atom Bombardment | 1997 |
Mitochondrial carnitine-acylcarnitine translocase deficiency presenting as sudden neonatal death.
Topics: Adult; Amnion; Breast Feeding; Carnitine; Carnitine Acyltransferases; Carnitine O-Palmitoyltransferase; Chorion; Diagnosis, Differential; Fasting; Fatal Outcome; Fatty Acid Desaturases; Fatty Acids; Fatty Liver; Female; Fetal Diseases; Fibroblasts; Genes, Recessive; Humans; Infant, Newborn; Kidney Diseases; Lipid Metabolism, Inborn Errors; Milk, Human; Mitochondria; Muscular Diseases; Oxidation-Reduction; Palmitoylcarnitine; Pregnancy; Prenatal Diagnosis; Skin; Stress, Physiological; Sudden Infant Death; Triglycerides | 1997 |
Effect of palmitoylcarnitine on the cellular differentiation, proliferation and protein kinase C activity in neuroblastoma nb-2a cells.
Topics: Animals; Carnitine; Cell Differentiation; Cell Division; Enzyme Inhibitors; Epoxy Compounds; Mice; Neuroblastoma; Palmitoylcarnitine; Protein Kinase C; Tumor Cells, Cultured | 1997 |
Effect of L-carnitine and palmitoyl-L-carnitine on erythroid colony formation in fetal mouse liver cell culture.
Topics: Animals; Carnitine; Cells, Cultured; Dose-Response Relationship, Drug; Erythroid Precursor Cells; Erythropoiesis; Erythropoietin; Fetus; Humans; Liver; Mice; Mice, Inbred ICR; Palmitoylcarnitine; Recombinant Proteins | 1998 |
K+ current inhibition by amphiphilic fatty acid metabolites in rat ventricular myocytes.
Topics: Animals; Carnitine; Electric Conductivity; Extracellular Space; Fatty Acids; Heart Ventricles; Intracellular Membranes; Male; Myocardium; Palmitates; Palmitoyl Coenzyme A; Palmitoylcarnitine; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley | 1998 |
Functional characterization of the carnitine transporter defective in primary carnitine deficiency.
Topics: Acetylcarnitine; Anti-Arrhythmia Agents; Betaine; Binding, Competitive; Biological Transport; Carnitine; Carrier Proteins; Cells, Cultured; Fibroblasts; Humans; Kidney; Liver; Membrane Potentials; Organic Cation Transport Proteins; Palmitoylcarnitine; Potassium; Sodium; Solute Carrier Family 22 Member 5 | 1999 |
Comparisons of flux control exerted by mitochondrial outer-membrane carnitine palmitoyltransferase over ketogenesis in hepatocytes and mitochondria isolated from suckling or adult rats.
Topics: Animals; Animals, Suckling; Carbon Dioxide; Carnitine; Carnitine O-Palmitoyltransferase; Cells, Cultured; Energy Metabolism; Enzyme Inhibitors; Epoxy Compounds; Ketone Bodies; Liver; Malonyl Coenzyme A; Membrane Proteins; Mitochondria, Liver; Palmitic Acid; Palmitoyl Coenzyme A; Palmitoylcarnitine; Rats; Rats, Wistar | 1999 |
Carnitine-acylcarnitine translocase deficiency is a treatable disease.
Topics: Acetylcarnitine; Carnitine; Carnitine Acyltransferases; Female; Humans; Infant, Newborn; Lipid Metabolism, Inborn Errors; Palmitoylcarnitine; Treatment Outcome | 1999 |
Identification of two novel mutations in the hypoglycemic phenotype of very long chain acyl-CoA dehydrogenase deficiency.
Topics: Acyl-CoA Dehydrogenase, Long-Chain; Alleles; Carnitine; Child, Preschool; DNA, Complementary; Exons; Female; Fibroblasts; Humans; Hypoglycemia; Mitochondria; Mutation; Palmitoylcarnitine; Phenotype | 1999 |
Long-chain acylcarnitine induces Ca2+ efflux from the sarcoplasmic reticulum.
Topics: Animals; Calcium; Calcium Channels; Calcium-Transporting ATPases; Carnitine; Myocardium; Palmitoylcarnitine; Rabbits; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum | 2000 |
Regulation of the activity of caspases by L-carnitine and palmitoylcarnitine.
Topics: Acylation; Apoptosis; Carnitine; Carnitine O-Palmitoyltransferase; Caspase 3; Caspase 7; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Cell Line; Dose-Response Relationship, Drug; Enzyme Activation; fas Receptor; Fibroblasts; Humans; Jurkat Cells; Palmitoyl Coenzyme A; Palmitoylcarnitine; Staurosporine | 2000 |
The interaction of ferrocytochrome c with long-chain fatty acids and their CoA and carnitine esters.
Topics: Acyl Coenzyme A; Animals; Carnitine; Cytochrome c Group; Fatty Acids; Fatty Alcohols; Horses; Ligands; Nuclear Magnetic Resonance, Biomolecular; Oleic Acid; Palmitoylcarnitine; Spectrum Analysis | 2000 |
Relevance of fatty acid oxidation in regulation of the outer mitochondrial membrane permeability for ADP.
Topics: Adenosine Diphosphate; Animals; Biological Transport; Carnitine; Fatty Acids; Intracellular Membranes; Male; Mitochondria, Heart; Oxidative Phosphorylation; Oxygen Consumption; Palmitoyl Coenzyme A; Palmitoylcarnitine; Permeability; Rats | 2001 |
Tandem mass spectrometric assay for the determination of carnitine palmitoyltransferase II activity in muscle tissue.
Topics: Acetylcarnitine; Carnitine; Carnitine O-Acetyltransferase; Carnitine O-Palmitoyltransferase; Humans; Kinetics; Mass Spectrometry; Muscles; Muscular Diseases; Palmitoylcarnitine; Spectrophotometry | 2002 |
Screening for carnitine palmitoyltransferase II deficiency by tandem mass spectrometry.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Carnitine; Carnitine O-Palmitoyltransferase; Child; Child, Preschool; Female; Humans; Infant; Male; Mass Screening; Mass Spectrometry; Middle Aged; Palmitoylcarnitine | 2002 |
A novel mitochondrial carnitine-acylcarnitine translocase induced by partial hepatectomy and fasting.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Biological Transport; Blotting, Northern; Blotting, Western; Brain; Carnitine; Carnitine Acyltransferases; DNA, Complementary; Escherichia coli; Fatty Acids; Food Deprivation; Genetic Complementation Test; Humans; Immunohistochemistry; Lipid Metabolism; Liver; Mice; Mice, Inbred C57BL; Mitochondria; Mitochondrial Proteins; Molecular Sequence Data; Palmitoylcarnitine; Plasmids; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Time Factors; Tissue Distribution | 2003 |
CARNITINE IN INTERMEDIARY METABOLISM. THE BIOSYNTHESIS OF PALMITYLCARNITINE BY CELL SUBFRACTIONS.
Topics: Carnitine; Folic Acid; Lipid Metabolism; Liver; Metabolism; Palmitic Acid; Palmitoylcarnitine; Rats; Research; Vitamin B Complex | 1963 |
A comparison of in vitro acylcarnitine profiling methods for the diagnosis of classical and variant short chain acyl-CoA dehydrogenase deficiency.
Topics: Acyl-CoA Dehydrogenase; Butyric Acid; Butyryl-CoA Dehydrogenase; Carbon Isotopes; Carnitine; Deuterium; DNA Mutational Analysis; Fibroblasts; Heterozygote; Homozygote; Humans; Malonates; Mutation, Missense; Palmitic Acid; Palmitoylcarnitine; Polymorphism, Genetic; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Spiro Compounds | 2003 |
Membrane transport of fatty acylcarnitine and free L-carnitine by rat liver microsomes.
Topics: Animals; Biological Transport; Carnitine; Endoplasmic Reticulum; Enzyme Inhibitors; Genes, Reporter; Intracellular Membranes; Male; Mersalyl; Microsomes, Liver; Palmitoyl Coenzyme A; Palmitoylcarnitine; Rats; Rats, Sprague-Dawley | 2004 |
Cysteine-scanning mutagenesis of muscle carnitine palmitoyltransferase I reveals a single cysteine residue (Cys-305) is important for catalysis.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Blotting, Western; Carnitine; Carnitine O-Palmitoyltransferase; Catalysis; Cysteine; DNA Primers; Humans; Kinetics; Malonyl Coenzyme A; Models, Chemical; Molecular Sequence Data; Mutagenesis; Mutation; Myocardium; Palmitic Acid; Palmitoylcarnitine; Pichia; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine | 2005 |
Strategy for the isolation, derivatization, chromatographic separation, and detection of carnitine and acylcarnitines.
Topics: Acetonitriles; Acetophenones; Acetylcarnitine; Animals; Blood Chemical Analysis; Carnitine; Chemical Precipitation; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Humans; Liver; Male; Mass Spectrometry; Methanol; Molecular Structure; Palmitoylcarnitine; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Serum Albumin; Silica Gel; Silicon Dioxide; Solid Phase Extraction | 2005 |
Increased carnitine-dependent fatty acid uptake into mitochondria of human colon cancer cells induces apoptosis.
Topics: Apoptosis; bcl-X Protein; Carnitine; Cell Line; Ceramides; Colonic Neoplasms; Down-Regulation; Drug Combinations; Fatty Acids; HT29 Cells; Humans; Mitochondria; Palmitic Acids; Palmitoylcarnitine; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species | 2005 |
Measurement of stable isotopic enrichment and concentration of long-chain fatty acyl-carnitines in tissue by HPLC-MS.
Topics: Animals; Carbon Isotopes; Carnitine; Chromatography, High Pressure Liquid; Deuterium; Fluorocarbons; Male; Methods; Muscle, Skeletal; Palmitic Acid; Palmitoylcarnitine; Rabbits; Reference Standards; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization | 2006 |
Increased mitochondrial palmitoylcarnitine/carnitine countertransport by flavone causes oxidative stress and apoptosis in colon cancer cells.
Topics: Apoptosis; Biological Transport; Carnitine; Colonic Neoplasms; Flavones; HT29 Cells; Humans; Mitochondria; Oxidative Stress; Palmitoylcarnitine; Superoxides | 2005 |
Carnitine supplementation induces acylcarnitine production in tissues of very long-chain acyl-CoA dehydrogenase-deficient mice, without replenishing low free carnitine.
Topics: Acyl-CoA Dehydrogenase, Long-Chain; Animals; Betaine; Carnitine; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dietary Supplements; Humans; Lipid Metabolism, Inborn Errors; Liver; Mice; Mice, Knockout; Muscle, Skeletal; Palmitoyl Coenzyme A; Palmitoylcarnitine; Physical Exertion; Time Factors | 2008 |
Liquid chromatography/mass spectrometry determination of endogenous plasma acetyl and palmitoyl carnitines as potential biomarkers of beta-oxidation in mice.
Topics: Animals; Biomarkers; Calibration; Carnitine; Chromatography, Liquid; Isotope Labeling; Male; Mass Spectrometry; Mice; Mice, Inbred Strains; Molecular Structure; Oxidation-Reduction; Palmitoylcarnitine; Reference Standards; Reproducibility of Results; Sensitivity and Specificity | 2008 |
Comparison of amino acids and acylcarnitines assay methods used in newborn screening assays by tandem mass spectrometry.
Topics: Amino Acids; Butanols; Carnitine; Humans; Infant, Newborn; Leucine; Metabolic Diseases; Methionine; Neonatal Screening; Palmitoylcarnitine; Phenylalanine; Quality Control; Tandem Mass Spectrometry | 2010 |
Absorption enhancement effect of acylcarnitines through changes in tight junction protein in Caco-2 cell monolayers.
Topics: Absorption; beta-Cyclodextrins; Biological Transport; Caco-2 Cells; Carnitine; Cell Membrane; Cholesterol; Claudins; Dextrans; Fluorescein-5-isothiocyanate; Humans; Laurates; Membrane Proteins; Palmitoylcarnitine; Tight Junctions | 2011 |
Effects of acylcarnitines on efflux transporting system in Caco-2 cell monolayers.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Carnitine; Dextrans; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Isoquinolines; L-Lactate Dehydrogenase; Laurates; Palmitoylcarnitine | 2010 |
Identification by site-directed mutagenesis of a hydrophobic binding site of the mitochondrial carnitine/acylcarnitine carrier involved in the interaction with acyl groups.
Topics: Acylation; Animals; Binding Sites; Carnitine; Carnitine Acyltransferases; Computational Biology; Enzyme Inhibitors; Hydrophobic and Hydrophilic Interactions; Kinetics; Mitochondria; Models, Molecular; Mutagenesis, Site-Directed; Mutant Proteins; Palmitoylcarnitine; Protein Binding; Rats; Time Factors | 2012 |
Disturbed carnitine regulation in chronic heart failure--increased plasma levels of palmitoyl-carnitine are associated with poor prognosis.
Topics: Adult; Aged; Biomarkers; Carnitine; Chronic Disease; Disease Progression; Female; Heart Failure; Humans; Male; Middle Aged; Palmitoylcarnitine; Prognosis | 2013 |
Increases in bioavailability of poorly absorbed drug by acylcarnitine.
Topics: Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Carnitine; Claudin-4; Colon; Fluorescent Dyes; Injections, Intravenous; Intestinal Absorption; Isoquinolines; Jejunum; L-Lactate Dehydrogenase; Laurates; Male; Palmitoylcarnitine; Rats; Rats, Wistar | 2012 |
Hyperinsulinemia and skeletal muscle fatty acid trafficking.
Topics: Adult; Carbon Radioisotopes; Carnitine; Cohort Studies; Down-Regulation; Fatty Acids, Nonesterified; Female; Glucose Clamp Technique; Humans; Hyperinsulinism; Infusions, Intravenous; Insulin; Insulin Resistance; Male; Middle Aged; Muscle, Skeletal; Oleic Acid; Palmitic Acid; Palmitoylcarnitine; Sex Characteristics; Triglycerides; Young Adult | 2013 |
Biochemical competition makes fatty-acid β-oxidation vulnerable to substrate overload.
Topics: Animals; Carnitine; Fatty Acids; Female; Kinetics; Liver; Metabolic Networks and Pathways; Mitochondria; Models, Biological; NAD; Obesity; Oxidation-Reduction; Palmitoyl Coenzyme A; Palmitoylcarnitine; Rats; Rats, Wistar; Reproducibility of Results | 2013 |
Quantification of plasma carnitine and acylcarnitines by high-performance liquid chromatography-tandem mass spectrometry using online solid-phase extraction.
Topics: Acetylcarnitine; Carnitine; Chromatography, High Pressure Liquid; Humans; Limit of Detection; Methanol; Palmitoylcarnitine; Reproducibility of Results; Solid Phase Extraction | 2013 |
The mechanism of Intralipid®-mediated cardioprotection complex IV inhibition by the active metabolite, palmitoylcarnitine, generates reactive oxygen species and activates reperfusion injury salvage kinases.
Topics: Animals; Cardiotonic Agents; Carnitine; Electron Transport Complex IV; Emulsions; Heart; Male; MAP Kinase Signaling System; Mitochondria, Heart; Myocardial Reperfusion Injury; Palmitoylcarnitine; Phospholipids; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Soybean Oil; Ventricular Function, Left | 2014 |
Functional analysis of iPSC-derived myocytes from a patient with carnitine palmitoyltransferase II deficiency.
Topics: Bezafibrate; Carnitine; Carnitine O-Palmitoyltransferase; Cell Differentiation; Cells, Cultured; Fibroblasts; Gene Expression Regulation; Humans; Male; Metabolism, Inborn Errors; Muscle Cells; Palmitoylcarnitine; Pluripotent Stem Cells; Young Adult | 2014 |
The effect of high-intensity training on mitochondrial fat oxidation in skeletal muscle and subcutaneous adipose tissue.
Topics: Adult; Carnitine; Exercise; Female; Humans; Male; Mitochondria; Mitochondria, Muscle; Muscle, Skeletal; Overweight; Oxidative Phosphorylation; Oxygen Consumption; Palmitoylcarnitine; Subcutaneous Fat | 2015 |
Long-chain acylcarnitine content determines the pattern of energy metabolism in cardiac mitochondria.
Topics: Animals; Carnitine; Energy Metabolism; Fasting; Fatty Acids; Glucose; Male; Mice; Mice, Inbred ICR; Mitochondria, Heart; Models, Animal; Palmitoylcarnitine; Rats; Rats, Wistar | 2014 |
Transorgan fluxes in a porcine model reveal a central role for liver in acylcarnitine metabolism.
Topics: Acetylcarnitine; Animals; Carnitine; Catheters, Indwelling; Crosses, Genetic; Female; Intestinal Mucosa; Intestines; Kidney; Lipid Metabolism; Liver; Models, Biological; Olive Oil; Organ Specificity; Palmitoylcarnitine; Plant Oils; Postprandial Period; Sus scrofa | 2015 |
Metabolic Phenotypes of Carotid Atherosclerotic Plaques Relate to Stroke Risk: An Exploratory Study.
Topics: Aged; Aged, 80 and over; Arachidonic Acid; Biomarkers; Carnitine; Carotid Stenosis; Case-Control Studies; Female; Humans; Male; Metabolomics; Middle Aged; Palmitoylcarnitine; Phenotype; Plaque, Atherosclerotic; Risk Factors; Stroke | 2016 |
Efficacy of bezafibrate on fibroblasts of glutaric acidemia type II patients evaluated using an in vitro probe acylcarnitine assay.
Topics: Adolescent; Adult; Age of Onset; Bezafibrate; Carnitine; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enzyme Activators; Female; Fibroblasts; Humans; Infant; Infant, Newborn; Lipid Regulating Agents; Male; Multiple Acyl Coenzyme A Dehydrogenase Deficiency; Palmitoylcarnitine; Peroxisome Proliferator-Activated Receptors; Skin | 2017 |
Palmitoyl-carnitine production by blood cells associates with the concentration of circulating acyl-carnitines in healthy overweight women.
Topics: Adult; Aged; Blood Cells; Blood Glucose; Body Mass Index; Carnitine; Diabetes Mellitus, Type 2; Female; Humans; Hyperinsulinism; Insulin; Insulin Resistance; Lipid Metabolism; Middle Aged; Overweight; Oxidation-Reduction; Palmitates; Palmitoylcarnitine | 2017 |
Acute and long-term administration of palmitoylcarnitine induces muscle-specific insulin resistance in mice.
Topics: Animals; Blood Glucose; Carbohydrate Metabolism; Carnitine; Dietary Fats; Energy Metabolism; Glucose; Humans; Insulin; Insulin Resistance; Lipid Metabolism; Mice; Muscle, Skeletal; Palmitoylcarnitine | 2017 |
Metabolite profiling of plasma in patients with ossification of the posterior longitudinal ligament.
Topics: Aged; Carnitine; Case-Control Studies; Cervical Vertebrae; Fatty Acids; Humans; Male; Metabolome; Middle Aged; Ossification of Posterior Longitudinal Ligament; Palmitoylcarnitine; Thiazolidines; Thyroxine | 2018 |
Association between 4-year all-cause mortality and carnitine profile in maintenance hemodialysis patients.
Topics: Acetylcarnitine; Aged; Carnitine; Cause of Death; Chromatography, Liquid; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Palmitoylcarnitine; Proportional Hazards Models; Renal Dialysis; Survival Analysis; Tandem Mass Spectrometry | 2018 |
Novel Biochemical Insights in the Cerebrospinal Fluid of Patients with Neurosyphilis Based on a Metabonomics Study.
Topics: Adult; Bilirubin; Biomarkers; Carnitine; Dinoprostone; Fatty Acids, Unsaturated; Female; Histidine; Humans; Male; Metabolome; Middle Aged; Neurosyphilis; Palmitoylcarnitine | 2019 |
Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometry Imaging of Lipids in Experimental Model of Traumatic Brain Injury Detecting Acylcarnitines as Injury Related Markers.
Topics: Animals; Biomarkers; Brain; Brain Injuries, Traumatic; Carnitine; Disease Models, Animal; Image Processing, Computer-Assisted; Lipid Metabolism; Lipids; Male; Microglia; Palmitoylcarnitine; Rats, Sprague-Dawley; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry | 2019 |