carnitine has been researched along with palmitoyl coenzyme a in 62 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 31 (50.00) | 18.7374 |
| 1990's | 13 (20.97) | 18.2507 |
| 2000's | 14 (22.58) | 29.6817 |
| 2010's | 4 (6.45) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Berge, R; Farstad, M | 1 |
| Bavilin, VA; Filippova, SN; Panov, AV | 1 |
| Albizzati, MG; Bassi, S; Cerri, C; Frattola, L; Scarlato, G | 1 |
| Wood, JM | 1 |
| Busch, U; Chang, CH; Entman, ML; Hanley, HG; Hartley, CJ; Lewis, RM; Morgan, WJ; Schwartz, A; Swain, JA; Wood, JM | 1 |
| Nozu, F; Takeyama, N; Tanaka, T | 1 |
| McMurray, WC; Mok, AY | 1 |
| Murthy, MS; Pande, SV; Ramsay, RR | 1 |
| Savino, EA; Varela, A | 1 |
| Bobyleva-Guarriero, V; Di Lisa, F; Menabò, R; Miotto, G; Siliprandi, N | 1 |
| Bartlett, K; Sherratt, HS; Turnbull, DM; Watmough, NJ | 1 |
| Berge, RK; Lembke, B; Mentlein, R; Vik, H | 1 |
| Brady, LJ; Brady, PS; Colucci, WJ; Gandour, RD; Stelly, TC | 1 |
| Corstorphine, CG; Kelliher, MG; Zammit, VA | 1 |
| Eacho, PI; Foxworthy, PS | 1 |
| Brady, LJ; Brady, PS; Dunker, AK | 1 |
| Bezard, J; Cao Danh, H; Clouet, P; Henninger, C; Pascal, M | 1 |
| Brady, LJ; Brady, PS | 1 |
| Grantham, BD; Zammit, VA | 1 |
| De Villiers, M; Lochner, A | 1 |
| Heymann, E; Mentlein, R; Reuter, G | 1 |
| Zammit, VA | 1 |
| Bird, MI; Saggerson, ED | 1 |
| McMillin-Wood, J; Wolkowicz, PE | 1 |
| Arshad, JH; Holdsworth, ES | 1 |
| Helfman, DM; Katoh, N; Kuo, JF; Wrenn, RW | 1 |
| Elson, CE; Mak, IT; Shrago, E | 1 |
| Paulson, DJ; Shug, AL; Ward, KM | 1 |
| Bieber, LL; Fiol, CJ | 1 |
| Bridges, JW; Elcombe, CR; Mitchell, AM | 1 |
| Foster, DW; Long, CS; McGarry, JD; Mills, SE | 1 |
| Hurley, B; Severson, DL | 1 |
| Kurup, CK; Mittal, B | 1 |
| Cook, GA; Kashfi, K | 1 |
| Bartlett, K; Pourfarzam, M | 1 |
| Reichmann, H; Schäfer, J; Turnbull, DM | 1 |
| Bell, PA; Dragland, CJ; Mann, WR; Yan, B | 1 |
| Bieber, LL; Wagner, M | 1 |
| Gustafson, B; Ransnäs, LA | 1 |
| Arvidson, DN; Cregg, JM; de Vries, Y; Shi, J; Woldegiorgis, G; Zhu, H | 1 |
| Cohen, I; Esser, V; Girard, J; Kohl, C; McGarry, JD; Prip-Buus, C | 1 |
| Rozanski, GJ; Xu, Z | 1 |
| Elliott, KR; Krauss, S; New, KJ; Quant, PA | 1 |
| El-Merzabani, MM; Khalifa, MH; Osman, AM; Rezk, BM; Sayed-Ahmed, MM; Shouman, SA | 1 |
| Cameron, JM; Fraser, F; Jackson, VN; Price, NT; Zammit, VA | 1 |
| Adachi, S; Babior, BM; Esser, V; Gottlieb, RA; Konyavko, M; McGarry, JD; Mutomba, MC; Yokoyama, CB; Yuan, H | 1 |
| Fraser, F; Padovese, R; Zammit, VA | 1 |
| Arita, K; Asami, M; Doi, Y; Furuno, T; Inoue, M; Kanno, T; Utsumi, K; Utsumi, T | 1 |
| Jackson, VN; Price, NT; Zammit, VA | 1 |
| Liobikas, J; Majiene, D; Toleikis, A; Trumbeckaite, S | 1 |
| Dai, J; Haro, D; Marrero, PF; Napal, L; Treber, M; Woldegiorgis, G | 1 |
| NORUM, KR | 1 |
| Asins, G; Gómez-Puertas, P; Hegardt, FG; López-Viñas, E; Morillas, M; Serra, D; Valencia, A | 1 |
| Gooding, JM; Saggerson, ED; Shayeghi, M | 1 |
| Liebig, M; Mayatepek, E; Mueller, M; Ruiter, J; Schymik, I; Spiekerkoetter, U; Strauss, AW; Wanders, RJ; Wendel, U | 1 |
| Carrasco, P; Casals, N; Gratacós, E; Hegardt, FG; Jáuregui, O; Sierra, AY | 1 |
| Mayatepek, E; Primassin, S; Spiekerkoetter, U; Ter Veld, F | 1 |
| Izumi, T; Korematsu, S; Kosugi, Y; Kumamoto, T; Yamaguchi, S | 1 |
| Oyanagi, E; Sasaki, J; Uchida, M; Utsumi, K; Yano, H | 1 |
| Gross, RW; Jenkins, CM; Kiebish, MA; Mancuso, DJ; Moon, SH; Sims, HF | 1 |
| Holloway, GP; Koves, TR; Muoio, DM; Neufer, PD; Perry, CG; Smith, BK; Smith, JC; Wright, DC | 1 |
| Bakker, BM; Bleeker, A; den Besten, G; Gerding, A; Groen, BK; Houten, SM; Krab, K; Reijngoud, DJ; Simons, SM; Touw, CM; van Eunen, K | 1 |
62 other study(ies) available for carnitine and palmitoyl coenzyme a
| Article | Year |
|---|---|
On the capacity of the beta-oxidation of palmitate and palmitoyl-esters in rat liver mitochondria.
Topics: Acyl Coenzyme A; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Carbon Dioxide; Carnitine; Coenzyme A; Male; Mitochondria, Liver; NAD; Oxidation-Reduction; Palmitates; Palmitic Acids; Palmitoyl Coenzyme A; Palmitoyl-CoA Hydrolase; Palmitoylcarnitine; Rats | 1978 |
[Effect of palmitoyl-CoA binding with adenine nucleotide translocase on energization of mitochondria].
Topics: Acyl Coenzyme A; Adenosine Diphosphate; Animals; Carnitine; Hydrogen-Ion Concentration; Intracellular Membranes; Kinetics; Male; Mitochondria, Liver; Mitochondrial ADP, ATP Translocases; Mitochondrial Swelling; Nucleotidyltransferases; Oligomycins; Oxidative Phosphorylation; Palmitoyl Coenzyme A; Rats | 1979 |
A case of lipid storage myopathy with carnitine deficiency. Biochemical and electromyographic correlations.
Topics: Adult; Carnitine; Carnitine O-Acetyltransferase; Carnitine O-Palmitoyltransferase; Cholesterol; Electromyography; Glycogen; Humans; Lipase; Lipid Metabolism; Male; Muscular Diseases; Palmitoyl Coenzyme A; Phospholipids; Triglycerides | 1977 |
Effects of palmityl coenzyme A and palmitylcarnitine on phosphorylating respiration in heart mitochondria.
Topics: Acyl Coenzyme A; Adenosine Diphosphate; Animals; Carnitine; Dogs; Glutamates; Kinetics; Malates; Mitochondria, Heart; Mitochondrial Swelling; Oxygen Consumption; Palmitoyl Coenzyme A; Palmitoylcarnitine; Rabbits; Succinates | 1978 |
Biochemical and morphological correlates of acute experimental myocardial ischemia in the dog. IV. Energy mechanisms during very early ischemia.
Topics: Acyl Coenzyme A; Acyltransferases; Animals; Carnitine; Carnitine O-Palmitoyltransferase; Citric Acid Cycle; Coronary Disease; Dogs; Glutamates; Glycogen; Mitochondria, Heart; Myocardium; Oxidation-Reduction; Oxygen Consumption; Palmitoyl Coenzyme A; Palmitoylcarnitine; Papillary Muscles; Phosphorylase b; Phosphorylases | 1979 |
Changes of hepatic fatty acid metabolism produced by chronic thioacetamide administration in rats.
Topics: Animals; Carnitine; Carnitine O-Palmitoyltransferase; Fatty Acids; Ketone Bodies; Liver; Liver Cirrhosis, Experimental; Male; Malonyl Coenzyme A; Mitochondria, Liver; Oxidation-Reduction; Oxygen; Palmitoyl Coenzyme A; Palmitoylcarnitine; Rats; Rats, Inbred Strains; Thioacetamide; Time Factors | 1992 |
Biosynthesis of phosphatidic acid by glycerophosphate acyltransferases in rat liver mitochondria and microsomes.
Topics: Acylation; Animals; Carnitine; Cations, Divalent; Detergents; Glycerol-3-Phosphate O-Acyltransferase; Glycerophosphates; Membrane Proteins; Microsomes, Liver; Mitochondria, Liver; Palmitoyl Coenzyme A; Palmitoylcarnitine; Phosphatidic Acids; Rats | 1990 |
Acyl-CoA chain length affects the specificity of various carnitine palmitoyltransferases with respect to carnitine analogues. Possible application in the discrimination of different carnitine palmitoyltransferase activities.
Topics: Acyl Coenzyme A; Acyltransferases; Animals; Betaine; Carnitine; Carnitine O-Palmitoyltransferase; Intracellular Membranes; Kinetics; Microbodies; Mitochondria, Liver; Palmitoyl Coenzyme A; Rats; Substrate Specificity | 1990 |
Effects of long-chain fatty-acyl esters of coenzyme A and carnitine on cell-free rat heart preparations.
Topics: Acyl Coenzyme A; Animals; Carnitine; Female; Glycolysis; Heart; In Vitro Techniques; Lactates; Lactic Acid; Male; Myocardium; Palmitoyl Coenzyme A; Rats; Tissue Extracts | 1987 |
Ca2+-mediated action of long-chain acyl-CoA on liver mitochondria energy-linked processes.
Topics: Acyl Coenzyme A; Animals; Betaine; Calcium; Carnitine; Carnitine O-Palmitoyltransferase; Egtazic Acid; Energy Metabolism; Magnesium; Membrane Potentials; Mitochondria, Liver; Palmitoyl Coenzyme A; Phosphates; Rats; Ruthenium Red | 1989 |
Measurement of the acyl-CoA intermediates of beta-oxidation by h.p.l.c. with on-line radiochemical and photodiode-array detection. Application to the study of [U-14C]hexadecanoate oxidation by intact rat liver mitochondria.
Topics: Acyl Coenzyme A; Animals; Carnitine; Chromatography, High Pressure Liquid; Mitochondria, Liver; Oxidation-Reduction; Palmitic Acids; Palmitoyl Coenzyme A; Rats; Rotenone | 1989 |
Different induction of microsomal carboxylesterases, palmitoyl-CoA hydrolase and acyl-L-carnitine hydrolase in rat liver after treatment with clofibrate.
Topics: Acetanilides; Animals; Carboxylic Ester Hydrolases; Carnitine; Clofibrate; Enzyme Induction; Isoelectric Point; Male; Microsomes, Liver; Palmitoyl Coenzyme A; Palmitoyl-CoA Hydrolase; Propanidid; Rats; Rats, Inbred Strains; Thiolester Hydrolases | 1986 |
Hemipalmitoylcarnitinium, a strong competitive inhibitor of purified hepatic carnitine palmitoyltransferase.
Topics: Acyltransferases; Animals; Binding, Competitive; Carnitine; Carnitine O-Acetyltransferase; Carnitine O-Palmitoyltransferase; Choline; Kinetics; Liver; Palmitoyl Coenzyme A; Palmitoylcarnitine; Rats | 1988 |
Evidence for distinct functional molecular sizes of carnitine palmitoyltransferases I and II in rat liver mitochondria.
Topics: Acyltransferases; Animals; Carnitine; Carnitine O-Palmitoyltransferase; Female; Isoenzymes; Kinetics; Mitochondria, Liver; Palmitoyl Coenzyme A; Rats; Rats, Inbred Strains | 1988 |
Inhibition of hepatic fatty acid oxidation at carnitine palmitoyltransferase I by the peroxisome proliferator 2-hydroxy-3-propyl-4-[6-(tetrazol-5-yl) hexyloxy]acetophenone.
Topics: Acetophenones; Acyltransferases; Animals; Azoles; Caprylates; Carnitine; Carnitine O-Palmitoyltransferase; Fatty Acids; In Vitro Techniques; Isoenzymes; Ketone Bodies; Liver; Male; Microbodies; Oleic Acid; Oleic Acids; Oxidation-Reduction; Palmitoyl Coenzyme A; Palmitoylcarnitine; Rats; Rats, Inbred F344; Tetrazoles | 1988 |
Characterization of hepatic carnitine palmitoyltransferase. Use of bromoacyl derivatives and antibodies.
Topics: Acyl Coenzyme A; Acyltransferases; Animals; Antibodies; Carnitine; Carnitine O-Palmitoyltransferase; Detergents; Kinetics; Liposomes; Mitochondria, Liver; Octoxynol; Palmitoyl Coenzyme A; Palmitoylcarnitine; Polyethylene Glycols; Rats; Rats, Inbred Strains; Sonication | 1987 |
Effects of fenofibrate treatment on fatty acid oxidation in liver mitochondria of obese Zucker rats.
Topics: Animals; Carnitine; Carnitine O-Acetyltransferase; Fatty Acids; Fenofibrate; Hypolipidemic Agents; Male; Malonyl Coenzyme A; Mitochondria, Liver; Oxidation-Reduction; Palmitoyl Coenzyme A; Propionates; Rats; Rats, Zucker | 1987 |
Action in vivo and in vitro of 2-tetradecylglycidic acid, 2-tetradecylglycidyl-CoA and 2-tetradecylglycidylcarnitine on hepatic carnitine palmitoyltransferase.
Topics: Acyl Coenzyme A; Acyltransferases; Administration, Oral; Animals; Azetidines; Carnitine; Carnitine O-Palmitoyltransferase; Epoxy Compounds; Ethers, Cyclic; Fatty Acids; Female; Fluorescence Polarization; Hypoglycemic Agents; In Vitro Techniques; Kinetics; Liver; Male; Malonyl Coenzyme A; Mitochondria, Liver; Palmitoyl Coenzyme A; Rats; Rats, Inbred Strains | 1986 |
Binding of [14C]malonyl-CoA to rat liver mitochondria after blocking of the active site of carnitine palmitoyltransferase I. Displacement of low-affinity binding by palmitoyl-CoA.
Topics: Acyl Coenzyme A; Acyltransferases; Animals; Binding Sites; Carnitine; Carnitine O-Palmitoyltransferase; Coenzyme A; Isoenzymes; Malonyl Coenzyme A; Mitochondria, Liver; Palmitoyl Coenzyme A; Rats | 1986 |
Mitochondrial Ca2+ fluxes: role of free fatty acids, acyl-CoA and acylcarnitine.
Topics: Acyl Coenzyme A; Animals; Biological Transport, Active; Calcium; Carnitine; Kinetics; Linoleic Acid; Linoleic Acids; Male; Mitochondria, Heart; Oxygen Consumption; Palmitic Acid; Palmitic Acids; Palmitoyl Coenzyme A; Palmitoylcarnitine; Rats; Rats, Inbred Strains; Serum Albumin, Bovine | 1986 |
Specificity of two different purified acylcarnitine hydrolases from rat liver, their identity with other carboxylesterases, and their possible function.
Topics: Acetylcarnitine; Animals; Butyrylthiocholine; Carboxylic Ester Hydrolases; Carnitine; Hydrolysis; Isoelectric Point; Isoenzymes; Kinetics; Liver; Microsomes, Liver; Palmitoyl Coenzyme A; Rats | 1985 |
Effects of the mode of addition of acyl-CoA on the initial rate of formation of acylcarnitine in the presence of carnitine by intact rat liver mitochondria in vitro.
Topics: Acyl Coenzyme A; Albumins; Animals; Carnitine; Female; In Vitro Techniques; Mitochondria, Liver; Palmitoyl Coenzyme A; Palmitoylcarnitine; Rats; Rats, Inbred Strains; Time Factors | 1985 |
Interacting effects of L-carnitine and malonyl-CoA on rat liver carnitine palmitoyltransferase.
Topics: Acyl Coenzyme A; Acyltransferases; Animals; Carnitine; Carnitine O-Palmitoyltransferase; Kinetics; Male; Malonyl Coenzyme A; Mitochondria, Heart; Mitochondria, Liver; Palmitoyl Coenzyme A; Rats; Rats, Inbred Strains; Starvation | 1985 |
Respiration-dependent calcium ion uptake by two preparations of cardiac mitochondria. Effects of palmitoyl-coenzyme A and palmitoylcarnitine on calcium ion cycling and nicotinamide nucleotide reduction state.
Topics: Acyl Coenzyme A; Animals; Calcium; Carnitine; Cell Fractionation; Dogs; In Vitro Techniques; Kinetics; Mitochondria, Heart; NAD; NADP; Oxidation-Reduction; Palmitoyl Coenzyme A; Palmitoylcarnitine; Ruthenium Red | 1980 |
Stimulation of calcium efflux from rat liver mitochondria by adenosine 3'5 cyclic monophosphate.
Topics: Adenosine Triphosphate; Animals; Calcium; Carnitine; Cyclic AMP; Fasting; Male; Mitochondria, Liver; Oxidation-Reduction; Palmitoyl Coenzyme A; Rats | 1980 |
Differential regulation of calcium-dependent and calcium-independent cyclic nucleotide phosphodiesterases from heart by palmitoylcarnitine and palmitoyl coenzyme A.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Acyl Coenzyme A; Animals; Calcium; Carnitine; Cattle; Isoenzymes; Kinetics; Myocardium; Palmitoyl Coenzyme A; Palmitoylcarnitine; Structure-Activity Relationship; Trifluoperazine | 1982 |
The influence of linoleic acid intake on the kinetics of adenine nucleotide translocase.
Topics: Animals; Atractyloside; Carnitine; Dietary Fats; Kinetics; Linoleic Acids; Male; Mitochondria, Liver; Mitochondrial ADP, ATP Translocases; Nucleotidyltransferases; Oxygen Consumption; Palmitoyl Coenzyme A; Rats; Rats, Inbred Strains | 1983 |
Malonyl CoA inhibition of carnitine palmityltransferase in rat heart mitochondria.
Topics: Acyl Coenzyme A; Acyltransferases; Animals; Carnitine; Carnitine O-Palmitoyltransferase; Fasting; Malates; Malonyl Coenzyme A; Mitochondria, Heart; Mitochondrial ADP, ATP Translocases; Oxygen Consumption; Palmitoyl Coenzyme A; Pyruvates; Pyruvic Acid; Rats | 1984 |
Sigmoid kinetics of purified beef heart mitochondrial carnitine palmitoyltransferase. Effect of pH and malonyl-CoA.
Topics: Acyl Coenzyme A; Acyltransferases; Animals; Carnitine; Carnitine O-Palmitoyltransferase; Cattle; Hydrogen-Ion Concentration; Kinetics; Malonyl Coenzyme A; Mitochondria, Heart; Palmitoyl Coenzyme A; Protein Binding | 1984 |
Factors influencing peroxisome proliferation in cultured rat hepatocytes.
Topics: Animals; Carnitine; Cell Division; Cells, Cultured; Clofibric Acid; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Glucosephosphate Dehydrogenase; Hydrocortisone; Liver; Male; Microbodies; Palmitoyl Coenzyme A; Rats; Rats, Inbred Strains; Trichloroacetic Acid | 1984 |
Observations on the affinity for carnitine, and malonyl-CoA sensitivity, of carnitine palmitoyltransferase I in animal and human tissues. Demonstration of the presence of malonyl-CoA in non-hepatic tissues of the rat.
Topics: Acyl Coenzyme A; Acyltransferases; Animals; Carnitine; Carnitine O-Palmitoyltransferase; Dogs; Female; Guinea Pigs; Humans; In Vitro Techniques; Kinetics; Liver; Male; Malonyl Coenzyme A; Mitochondria; Muscles; Myocardium; Palmitoyl Coenzyme A; Rats; Rats, Inbred Strains; Starvation | 1983 |
Regulation of rat heart triacylglycerol ester hydrolases by free fatty acids, fatty acyl CoA and fatty acyl carnitine.
Topics: Acyl Coenzyme A; Animals; Carnitine; Fatty Acids, Nonesterified; In Vitro Techniques; Lipase; Male; Myocardium; Oleic Acid; Oleic Acids; Palmitoyl Coenzyme A; Rats; Rats, Inbred Strains | 1982 |
Purification of clofibrate-induced carnitine acetyltransferase from rat liver mitochondria.
Topics: Acetyl Coenzyme A; Acetylcarnitine; Acetyltransferases; Acyl Coenzyme A; Animals; Carnitine; Clofibrate; Enzyme Induction; Male; Mitochondria, Liver; Palmitoyl Coenzyme A; Rats; Temperature | 1980 |
Inhibition of carnitine palmitoyltransferase of the hepatic mitochondrial outer membrane (CPT-I) by 2-bromopalmitoyl-CoA.
Topics: Animals; Carnitine; Carnitine O-Palmitoyltransferase; Intracellular Membranes; Kinetics; Male; Mitochondria, Liver; Palmitoyl Coenzyme A; Rats; Rats, Sprague-Dawley | 1993 |
Skeletal muscle mitochondrial beta-oxidation of dicarboxylates.
Topics: Acyl Coenzyme A; Animals; Carbon Radioisotopes; Carnitine; Chromatography, High Pressure Liquid; Cyanides; Male; Mitochondria, Heart; Mitochondria, Muscle; Oxidation-Reduction; Palmitates; Palmitoyl Coenzyme A; Rats; Rats, Wistar | 1993 |
A rapid fluorometric method for the determination of carnitine palmitoyltransferase.
Topics: Animals; Carnitine; Carnitine O-Palmitoyltransferase; Cattle; Coenzyme A; Fluorometry; Humans; Liver; Maleimides; Muscles; Palmitoyl Coenzyme A; Rats; Reproducibility of Results | 1993 |
Kinetic, circular dichroism and fluorescence studies on heterologously expressed carnitine palmitoyltransferase II.
Topics: Animals; Carnitine; Carnitine O-Palmitoyltransferase; Circular Dichroism; Kinetics; Mitochondria, Liver; Palmitoyl Coenzyme A; Protein Conformation; Rats; Recombinant Proteins; Spectrometry, Fluorescence | 1995 |
Effect of pH and acyl-CoA chain length on the conversion of heart mitochondrial CPT-I/CPTo to a high affinity, malonyl-CoA-inhibited state.
Topics: Acyl Coenzyme A; Animals; Carnitine; Carnitine O-Palmitoyltransferase; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Hydrogen-Ion Concentration; Malonyl Coenzyme A; Mitochondria, Heart; Palmitoyl Coenzyme A; Rats | 1996 |
Palmitoyl-CoA stimulates cellular uptake and plasma membrane binding of carnitine.
Topics: Animals; Binding Sites; Biological Transport, Active; Carnitine; Cell Membrane; Mice; Palmitoyl Coenzyme A; Tumor Cells, Cultured | 1997 |
Functional studies of yeast-expressed human heart muscle carnitine palmitoyltransferase I.
Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Carnitine; Carnitine O-Palmitoyltransferase; Cloning, Molecular; Gene Expression; Humans; Immunoblotting; Kinetics; Malonyl Coenzyme A; Mitochondria; Molecular Sequence Data; Myocardium; Palmitoyl Coenzyme A; Pichia; Rats; Recombinant Proteins; RNA, Messenger | 1997 |
Topological and functional analysis of the rat liver carnitine palmitoyltransferase 1 expressed in Saccharomyces cerevisiae.
Topics: Animals; Carnitine; Carnitine O-Palmitoyltransferase; Mitochondria; Mitochondria, Liver; Palmitoyl Coenzyme A; Rabbits; Rats; Rats, Wistar; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Subcellular Fractions; Substrate Specificity | 1998 |
K+ current inhibition by amphiphilic fatty acid metabolites in rat ventricular myocytes.
Topics: Animals; Carnitine; Electric Conductivity; Extracellular Space; Fatty Acids; Heart Ventricles; Intracellular Membranes; Male; Myocardium; Palmitates; Palmitoyl Coenzyme A; Palmitoylcarnitine; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley | 1998 |
Comparisons of flux control exerted by mitochondrial outer-membrane carnitine palmitoyltransferase over ketogenesis in hepatocytes and mitochondria isolated from suckling or adult rats.
Topics: Animals; Animals, Suckling; Carbon Dioxide; Carnitine; Carnitine O-Palmitoyltransferase; Cells, Cultured; Energy Metabolism; Enzyme Inhibitors; Epoxy Compounds; Ketone Bodies; Liver; Malonyl Coenzyme A; Membrane Proteins; Mitochondria, Liver; Palmitic Acid; Palmitoyl Coenzyme A; Palmitoylcarnitine; Rats; Rats, Wistar | 1999 |
Propionyl-L-carnitine as potential protective agent against adriamycin-induced impairment of fatty acid beta-oxidation in isolated heart mitochondria.
Topics: Adenosine Triphosphate; Animals; Antibiotics, Antineoplastic; Cardiotonic Agents; Carnitine; Carnitine O-Palmitoyltransferase; Doxorubicin; Fatty Acids; In Vitro Techniques; Male; Mitochondria, Heart; Myocardium; Oxidation-Reduction; Palmitates; Palmitoyl Coenzyme A; Proteins; Rats; Rats, Sprague-Dawley | 2000 |
Use of six chimeric proteins to investigate the role of intramolecular interactions in determining the kinetics of carnitine palmitoyltransferase I isoforms.
Topics: Amino Acid Sequence; Animals; Carnitine; Carnitine O-Palmitoyltransferase; Cell Membrane; DNA, Complementary; Dose-Response Relationship, Drug; Inhibitory Concentration 50; Kinetics; Malonyl Coenzyme A; Molecular Sequence Data; Palmitoyl Coenzyme A; Pichia; Plasmids; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; Rats; Recombinant Fusion Proteins; Sequence Homology, Amino Acid | 2000 |
Regulation of the activity of caspases by L-carnitine and palmitoylcarnitine.
Topics: Acylation; Apoptosis; Carnitine; Carnitine O-Palmitoyltransferase; Caspase 3; Caspase 7; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Cell Line; Dose-Response Relationship, Drug; Enzyme Activation; fas Receptor; Fibroblasts; Humans; Jurkat Cells; Palmitoyl Coenzyme A; Palmitoylcarnitine; Staurosporine | 2000 |
Distinct kinetics of carnitine palmitoyltransferase i in contact sites and outer membranes of rat liver mitochondria.
Topics: Animals; Carnitine; Carnitine O-Palmitoyltransferase; Catalysis; Intracellular Membranes; Kinetics; Male; Malonyl Coenzyme A; Mitochondria, Liver; Palmitoyl Coenzyme A; Rats; Rats, Wistar | 2001 |
Roles of long chain fatty acids and carnitine in mitochondrial membrane permeability transition.
Topics: Animals; Carnitine; Cellular Senescence; Cephaloridine; Cephalosporins; Chlorpromazine; Cyclosporine; Cytochrome c Group; Dopamine Antagonists; Drug Interactions; Enzyme Inhibitors; Fatty Acids; Mitochondria, Liver; Mitochondrial Swelling; Palmitoyl Coenzyme A; PC12 Cells; Permeability; Phosphorylation; Rats; Rats, Wistar; Serum Albumin, Bovine | 2001 |
Specificity of the interactions between Glu-3, Ser-24, and Gln-30 within the N-terminal segment of rat liver mitochondrial overt carnitine palmitoyltransferase (L-CPT I) in determining the malonyl-CoA sensitivity of the enzyme.
Topics: Animals; Carnitine; Carnitine O-Palmitoyltransferase; DNA Primers; Glutamic Acid; Glutamine; Malonyl Coenzyme A; Mitochondria, Liver; Palmitoyl Coenzyme A; Peptide Fragments; Pichia; Plasmids; Point Mutation; Protein Structure, Secondary; Rats; Recombinant Proteins; Serine | 2001 |
Relevance of fatty acid oxidation in regulation of the outer mitochondrial membrane permeability for ADP.
Topics: Adenosine Diphosphate; Animals; Biological Transport; Carnitine; Fatty Acids; Intracellular Membranes; Male; Mitochondria, Heart; Oxidative Phosphorylation; Oxygen Consumption; Palmitoyl Coenzyme A; Palmitoylcarnitine; Permeability; Rats | 2001 |
A single amino acid change (substitution of the conserved Glu-590 with alanine) in the C-terminal domain of rat liver carnitine palmitoyltransferase I increases its malonyl-CoA sensitivity close to that observed with the muscle isoform of the enzyme.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Blotting, Western; Carnitine; Carnitine O-Palmitoyltransferase; Chickens; Dose-Response Relationship, Drug; Glutamic Acid; Glutamine; Humans; Immunoblotting; Kinetics; Liver; Lysine; Malonyl Coenzyme A; Mice; Molecular Sequence Data; Muscles; Mutation; Palmitoyl Coenzyme A; Pichia; Polymerase Chain Reaction; Protein Isoforms; Protein Structure, Tertiary; Rats; Sequence Homology, Amino Acid; Swine | 2003 |
PALMITYL-COA:CARNITINE PALMITYLTRANSFERASE. PURIFICATION FROM CALF-LIVER MITOCHONDRIA AND SOME PROPERTIES OF THE ENZYME.
Topics: Animals; Carnitine; Cattle; Chemical Phenomena; Chemistry; Esterases; Folic Acid; Hydrogen-Ion Concentration; Kinetics; Liver; Mitochondria; Mitochondria, Liver; Molecular Weight; Palmitoyl Coenzyme A; Research; Spectrophotometry; Transferases; Vitamin B Complex | 1964 |
Structural model of carnitine palmitoyltransferase I based on the carnitine acetyltransferase crystal.
Topics: Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Blotting, Western; Carnitine; Carnitine O-Acetyltransferase; Carnitine O-Palmitoyltransferase; Coenzyme A; Crystallization; Crystallography, X-Ray; Humans; Kinetics; Mice; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation, Missense; Palmitoyl Coenzyme A; Protein Conformation; Rats; Saccharomyces cerevisiae | 2004 |
Membrane transport of fatty acylcarnitine and free L-carnitine by rat liver microsomes.
Topics: Animals; Biological Transport; Carnitine; Endoplasmic Reticulum; Enzyme Inhibitors; Genes, Reporter; Intracellular Membranes; Male; Mersalyl; Microsomes, Liver; Palmitoyl Coenzyme A; Palmitoylcarnitine; Rats; Rats, Sprague-Dawley | 2004 |
Neonatal screening for very long-chain acyl-coA dehydrogenase deficiency: enzymatic and molecular evaluation of neonates with elevated C14:1-carnitine levels.
Topics: Acyl-CoA Dehydrogenase, Long-Chain; Biomarkers; Carnitine; Cohort Studies; Fatty Acids; Humans; Infant, Newborn; Lipid Metabolism, Inborn Errors; Lymphocytes; Neonatal Screening; Oxidation-Reduction; Palmitoyl Coenzyme A; Sequence Analysis, DNA; Spectrometry, Mass, Electrospray Ionization | 2006 |
A new LC-ESI-MS/MS method to measure long-chain acylcarnitine levels in cultured cells.
Topics: Acetonitriles; Animals; Carnitine; Carnitine O-Palmitoyltransferase; Chromatography, High Pressure Liquid; Formates; Mitochondria; Palmitoyl Coenzyme A; PC12 Cells; Rats; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Transfection | 2007 |
Carnitine supplementation induces acylcarnitine production in tissues of very long-chain acyl-CoA dehydrogenase-deficient mice, without replenishing low free carnitine.
Topics: Acyl-CoA Dehydrogenase, Long-Chain; Animals; Betaine; Carnitine; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dietary Supplements; Humans; Lipid Metabolism, Inborn Errors; Liver; Mice; Mice, Knockout; Muscle, Skeletal; Palmitoyl Coenzyme A; Palmitoylcarnitine; Physical Exertion; Time Factors | 2008 |
Novel mutation of early, perinatal-onset, myopathic-type very-long-chain acyl-CoA dehydrogenase deficiency.
Topics: Acyl Coenzyme A; Acyl-CoA Dehydrogenase, Long-Chain; Age of Onset; Carnitine; DNA Mutational Analysis; Fibroblasts; Humans; Infant, Newborn; Male; Metabolism, Inborn Errors; Muscles; Mutation; Palmitoyl Coenzyme A; Rhabdomyolysis; Skin; Treatment Outcome | 2009 |
Protective action of L-carnitine on cardiac mitochondrial function and structure against fatty acid stress.
Topics: Animals; Carnitine; Fatty Acids; Mitochondria, Heart; Mitochondrial Swelling; Oxygen Consumption; Palmitoyl Coenzyme A; Permeability; Rats; Stress, Physiological; Vitamin B Complex | 2011 |
Genetic ablation of calcium-independent phospholipase A(2)γ (iPLA(2)γ) attenuates calcium-induced opening of the mitochondrial permeability transition pore and resultant cytochrome c release.
Topics: Animals; Calcium; Carnitine; Carnitine O-Palmitoyltransferase; Cell Death; Cytochromes c; Energy Metabolism; Enzyme Inhibitors; Group VI Phospholipases A2; Lipid Metabolism; Mice; Mice, Knockout; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Palmitoyl Coenzyme A; Rabbits | 2012 |
Identification of a novel malonyl-CoA IC(50) for CPT-I: implications for predicting in vivo fatty acid oxidation rates.
Topics: Animals; Carnitine; Carnitine O-Palmitoyltransferase; Cell Membrane Permeability; Dose-Response Relationship, Drug; Fatty Acids; Inhibitory Concentration 50; Kinetics; Malonyl Coenzyme A; Mitochondria, Muscle; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; Oxidation-Reduction; Oxygen Consumption; Palmitoyl Coenzyme A; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley | 2012 |
Biochemical competition makes fatty-acid β-oxidation vulnerable to substrate overload.
Topics: Animals; Carnitine; Fatty Acids; Female; Kinetics; Liver; Metabolic Networks and Pathways; Mitochondria; Models, Biological; NAD; Obesity; Oxidation-Reduction; Palmitoyl Coenzyme A; Palmitoylcarnitine; Rats; Rats, Wistar; Reproducibility of Results | 2013 |