carnitine has been researched along with octanoylcarnitine in 79 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (26.58) | 18.7374 |
| 1990's | 13 (16.46) | 18.2507 |
| 2000's | 13 (16.46) | 29.6817 |
| 2010's | 29 (36.71) | 24.3611 |
| 2020's | 3 (3.80) | 2.80 |
| Authors | Studies |
|---|---|
| Amatruda, JM; Kiesow, LA; Lockwood, DH; Margolis, S | 1 |
| Harper, RD; Saggerson, ED | 1 |
| Cockburn, F; Farquharson, J; Jamieson, EC; Logan, RW; Muir, J | 1 |
| Gage, DA; Huang, ZH; Kossak, D; Li, BU; Penn, D; Rinaldo, P; Schmidt-Sommerfeld, E | 1 |
| Gnoni, GV; Muci, MR | 1 |
| Arrigoni Martelli, E; Bassani, E; Cardace, G; Corbelletta, C; Mancinelli, A; Marzo, A; Solbiati, M | 1 |
| Bhuiyan, AK; Pande, SV | 1 |
| Squire, RS | 1 |
| Millington, DS; Roe, CR | 1 |
| Brass, EP | 1 |
| Bieber, LL; Kerner, J; Lebenthal, E; Penn, D; Rossi, TM; Schmidt-Sommerfeld, E | 1 |
| Maltby, DA; Millington, DS; Roe, CR; Wellman, RB | 1 |
| Bohan, TP; Liberato, DJ; Millington, DS; Roe, CR; Yergey, AL | 1 |
| Kinnebrew, P; Maltby, DA; Millington, DS; Roe, CR | 1 |
| Bohan, TP; Chalmers, RA; Kahler, SG; Maltby, DA; Millington, DS; Roe, CR | 1 |
| Bruinvis, L; de Jager, JP; de Klerk, JB; Duran, M; Hofkamp, M; Ketting, D; Mitchell, G; Saudubray, JM; Wadman, SK | 1 |
| Beckeringh, TE; Bruinvis, L; Dorland, L; Duran, M; Ketting, D; van Vossen, R; Wadman, SK | 1 |
| Foster, DW; McGarry, JD | 1 |
| Chalmers, RA; Hoppel, CL; Roe, CR; Stacey, TE | 1 |
| Dorgan, DR; Kim, CS; Roe, CR | 1 |
| Kawashima, S; Nakatani, T; Ozawa, K; Tobe, T; Yasuda, K | 1 |
| Asano, M; Kamiyama, Y; Nakatani, T; Ozawa, K; Tobe, T; Ukikusa, M | 2 |
| Arinze, IJ; Parameswaran, M | 1 |
| Davis, EJ; Davis-van Thienen, W | 1 |
| Jones, CT | 1 |
| Zammit, VA | 1 |
| Brackett, JC; Finegold, DN; Hoffman, EP; Hoop, RC; Naylor, EW; Strauss, AW; Ziadeh, R | 1 |
| Hoppel, CL; Minkler, PE | 1 |
| Chace, DH; Chen, YT; Ding, JH; Iafolla, AK; Kahler, SG; Millington, DS; Roe, CR; Terada, N; Van Hove, JL; Zhang, W | 1 |
| Bennett, MJ; Duran, M; Penn, D; Santer, R; Schmidt-Sommerfeld, E; Stanley, CA | 1 |
| Novak, RF; Zangar, RC | 1 |
| Chace, DH; Hillman, SL; Naylor, EW; Van Hove, JL | 1 |
| Clayton, PT; Doig, M; Ghafari, S; Johnson, AW; Leonard, JV; Meaney, C; Morris, M; Taylor, C | 1 |
| Mroczkowska, JE; Naleçz, KA; Naleçz, MJ; Roux, FS | 1 |
| Gellerich, FN; Neuhof, C; Opalka, JR; Trumbeckaite, S; Zierz, S | 1 |
| Adam, BW; Chace, DH; DiPerna, JC; Hannon, WH | 1 |
| Craighead, HG; Henion, J; Kameoka, J; Zhang, H | 1 |
| Carpenter, K; Heath, D; Sim, KG; Wilcken, B; Wiley, V | 1 |
| Appleton, M; Bartlett, K; Craft, A; Morris, A; Pourfarzam, M | 1 |
| Liobikas, J; Majiene, D; Toleikis, A; Trumbeckaite, S | 1 |
| Lehotay, DC; LePage, J; Rockman-Greenberg, C; Thompson, JR | 1 |
| Hsiao, YS; Jogl, G; Tong, L | 1 |
| de Assis, DR; Dutra-Filho, CS; Ferreira, GC; Latini, A; Maria, RC; Schuck, PF; Wajner, M; Wannmacher, CM; Wyse, AT | 1 |
| Baumgartner, C; Baumgartner, D | 1 |
| Comeau, AM; Eaton, RB; Grady, GF; Hsu, HW; Marsden, D; Shih, VE; Strauss, AW; Zytkovicz, TH | 1 |
| Busch, U; Fingerhut, R; Liebl, B; Maier, EM; Muntau, AC; Nennstiel-Ratzel, U; Olgemöller, B; Pongratz, J; Roscher, AA; Röschinger, W | 1 |
| Adams, DJ; Arnold, GL; Caggana, M; Devincentis, E; Erbe, R; Galvin-Parton, PA; Kronn, D; Levy, PA; Mofidi, S; Nichols, M; Pellegrino, JE; Saavedra-Matiz, CA; Wasserstein, M | 1 |
| Chace, DH; De Jesús, VR; Hannon, WH; Lim, TH; Mei, JV | 1 |
| Besley, G; Dalton, N; Dezateux, C; Downing, M; Green, A; Henderson, M; Khalid, JM; Krywawych, S; Oerton, J; Wilcken, B; Wiley, V | 1 |
| Boushel, R; Dela, F; Hansen, CN; Kraunsøe, R; Mikines, KJ; Qvortrup, K; Schjerling, P; Støckel, M | 1 |
| Gavrilov, D; Highsmith, WE; Matern, D; McHugh, D; Oglesbee, D; Raymond, K; Rinaldo, P; Smith, EH; Thomas, C; Tortorelli, S | 1 |
| Andersen, JL; Dela, F; Hansen, CN; Helge, JW; Hey-Mogensen, M; Larsen, S; Madsbad, S; Stride, N; Worm, D | 1 |
| Grings, M; Knebel, LA; Leipnitz, G; Moura, AP; Ribeiro, CA; Tonin, AM; Wajner, M; Zanatta, Â | 1 |
| Dela, F; Gustafsson, F; Hey-Mogensen, M; Køber, L; Larsen, S; Lund, JT; Sander, K; Stride, N | 1 |
| Meadows, JA; Wargo, MJ | 1 |
| Alexandre-Gouabau, MC; Antignac, JP; Courant, F; Darmaun, D; Küster, A; Le Gall, G; Moyon, T; Tea, I | 1 |
| Moretti, S; Naccarato, A; Sindona, G; Tagarelli, A | 1 |
| Donzelli, M; Haschke, M; Krähenbühl, S; Morand, R | 1 |
| Danielsen, JH; Dela, F; Dybboe, R; Helge, JW; Larsen, S; Skaaby, S; Søgaard, D; Søndergård, SD; Vigelsoe, A | 1 |
| Hankemeier, T; Lindenburg, PW; Oedit, A; Schoonen, JW; van Duinen, V; Vulto, P | 1 |
| Bramwell, RC; Donato, AJ; Enz, RA; Hart, CR; Hazra, S; Henson, GD; Layec, G; Lesniewski, LA; Morgan, RG; Reihl, KD; Richardson, RS; Trinity, JD; Walker, AE | 1 |
| Hagar, A; Hall, PL; Wittenauer, A | 1 |
| Jung, S; Kim, M; Lee, JH; Lee, SH | 1 |
| Bernstone, L; Hall, SK; Lawson, AJ | 1 |
| Burgess, SL; Horscroft, JA; Hu, Y; Murray, AJ | 1 |
| Andrew, B; Bezuidenhout, N; George, S; Maarman, G; Madlala, HP; Mendham, A; Ojuka, E; Osiki, PO | 1 |
| Aukrust, P; Berge, RK; Damås, JK; Flo, TH; Landrø, L; Svardal, A; Ueland, T; Waagsbø, B; Øktedalen, O | 1 |
| Reiser, G; Schönfeld, P | 1 |
| Hoppel, CL; Ingalls, ST; Minkler, PE; Stoll, MSK | 1 |
| Al Rijjal, D; Batchuluun, B; Bhattacharjee, A; Burdett, E; Eversley, JA; Gunderson, EP; Liu, Y; Mohan, H; Prentice, KJ; Wheeler, MB | 1 |
| Jo, G; Oh, K; Seo, WK; Shin, MJ | 1 |
| Bosch, AM; de Vries, M; Derks, TGJ; Gozalbo, ER; Jager, EA; Kuijpers, MM; Mulder, MF; Schielen, PCJI; van Spronsen, FJ; Visser, G; Waterham, HR; Williams, M | 1 |
| Li, Y; Liu, Y; Song, J; Xu, J; Yang, Y; Zhu, R | 1 |
| Kim, DH; Kim, TH; Lee, A; Park, J; Shin, Y | 1 |
| Bovet, C; Gray, PC; Kruithof-de Julio, M; Minoli, M; Ng, CKY; Piscuoglio, S; Spahn, M; Thalmann, GN; Wehrhan, A; Zoni, E | 1 |
| Canfield, MA; Freedenberg, D; Hua, F; Hunt, P; Jackson, JF; Langlois, PH; Lee, R; Mandell, DJ; Reilly, B; Ruktanonchai, DJ; Rutenberg, GW; Villanacci, JF | 1 |
| Gornbein, JA; Koos, BJ | 1 |
| Li, HY; Li, YY; Mu, K; Sun, XC; Xu, J | 1 |
1 review(s) available for carnitine and octanoylcarnitine
| Article | Year |
|---|---|
Measurement of β-oxidation capacity of biological samples by respirometry: a review of principles and substrates.
Topics: Acyl Coenzyme A; Carnitine; Coenzyme A; Electrodes; Fatty Acids; Feedback, Physiological; Humans; Malates; Mitochondria; Oxidation-Reduction; Oxidative Phosphorylation; Oxygen Consumption; Palmitoylcarnitine | 2016 |
1 trial(s) available for carnitine and octanoylcarnitine
| Article | Year |
|---|---|
Screening for medium chain acyl-CoA dehydrogenase deficiency using electrospray ionisation tandem mass spectrometry.
Topics: Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenases; Adolescent; Age Distribution; Aging; Carnitine; Child; Child, Preschool; Fasting; Female; Heterozygote; Humans; Hypoglycemia; Infant; Infant, Newborn; Male; Mass Screening; Mass Spectrometry; Neonatal Screening; Reference Values; Reye Syndrome | 1998 |
77 other study(ies) available for carnitine and octanoylcarnitine
| Article | Year |
|---|---|
[14C]palmitate uptake in isolated rat liver mitochondria: effects of fasting, diabetes mellitus, and inhibitors of carnitine acyltransferase.
Topics: Acyltransferases; Adenosine Triphosphate; Animals; Caprylates; Carnitine; Carnitine Acyltransferases; Coenzyme A; Diabetes Mellitus, Experimental; Diabetic Ketoacidosis; Male; Mitochondria, Liver; Palmitates; Palmitic Acids; Rats; Starvation | 1978 |
Some aspects of fatty acid oxidation in isolated fat-cell mitochondria from rat.
Topics: Adenosine Triphosphate; Adipose Tissue; Animals; Bicarbonates; Caprylates; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Carnitine; Carnitine O-Palmitoyltransferase; Citrate (si)-Synthase; Coenzyme A; DNA; Fatty Acids; Glutamate Dehydrogenase; In Vitro Techniques; Malates; Male; Mitochondria; Mitochondria, Liver; Oxidation-Reduction; Oxygen Consumption; Pyruvates; Rats; Starvation | 1975 |
Direct gas chromatographic assay of urinary medium-chain fatty acylcarnitines by their thermal decomposition.
Topics: Acyl-CoA Dehydrogenase; Carnitine; Chromatography, Gas; Chromatography, High Pressure Liquid; Fatty Acid Desaturases; Hot Temperature; Humans | 1992 |
Urinary medium-chain acylcarnitines in medium-chain acyl-CoA dehydrogenase deficiency, medium-chain triglyceride feeding and valproic acid therapy: sensitivity and specificity of the radioisotopic exchange/high performance liquid chromatography method.
Topics: Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenases; Adolescent; Carnitine; Child; Child, Preschool; Chromatography, High Pressure Liquid; Humans; Infant; Lipid Metabolism, Inborn Errors; Sensitivity and Specificity; Triglycerides; Valproic Acid | 1992 |
Short-term effects of triiodothyronine on exogenous and de novo synthesized fatty acids in rat hepatocytes.
Topics: Animals; Carnitine; Carnitine O-Palmitoyltransferase; Cells, Cultured; Fatty Acids; Lipids; Liver; Oxidation-Reduction; Palmitic Acid; Palmitic Acids; Phospholipids; Rats; Triiodothyronine | 1991 |
Protein binding of L-carnitine family components.
Topics: Acetylcarnitine; Animals; Blood Proteins; Carnitine; Chromatography, Gel; Dogs; Humans; Palmitoylcarnitine; Protein Binding; Rats; Serum Albumin; Ultrafiltration | 1991 |
One-step facile synthesis of radioactive acyl-CoA and acylcarnitines using rat liver outer mitochondrial membrane as the enzyme source.
Topics: Acyl Coenzyme A; Animals; Caprylates; Carbon Radioisotopes; Carnitine; Intracellular Membranes; Isotope Labeling; Mitochondria, Liver; Palmitic Acid; Palmitic Acids; Rats; Submitochondrial Particles | 1991 |
Synthesis and purification of radioactive fatty acylcarnitines of high specific activity.
Topics: 1-Propanol; Carnitine; Chemistry Techniques, Analytical; Chromatography, Ion Exchange; Heptanes; Hydrochloric Acid; Palmitoylcarnitine; Tritium | 1991 |
Medium-chain acyl-CoA dehydrogenase deficiency.
Topics: Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenases; Carnitine; Humans; Mass Spectrometry | 1989 |
Metabolism of octanoyl- and palmitoylcarnitine by intact rat hepatocytes.
Topics: Animals; Carnitine; In Vitro Techniques; Ketone Bodies; Liver; Male; Palmitoylcarnitine; Rats; Rats, Inbred Strains | 1989 |
Quantitation of urinary carnitine esters in a patient with medium-chain acyl-coenzyme A dehydrogenase deficiency: effect of metabolic state and L-carnitine therapy.
Topics: Acetylcarnitine; Acyl-CoA Dehydrogenase; Carnitine; Child; Child, Preschool; Chromatography, High Pressure Liquid; Fasting; Fatty Acid Desaturases; Humans; Infant; Male | 1989 |
Post-mortem recognition of inherited metabolic disorders from specific acylcarnitines in tissue in cases of sudden infant death.
Topics: Acyl-CoA Dehydrogenase; Carnitine; Fatty Acid Desaturases; Female; Humans; Infant; Infant, Newborn; Male; Metabolism, Inborn Errors; Sudden Infant Death | 1987 |
Valproylcarnitine: a novel drug metabolite identified by fast atom bombardment and thermospray liquid chromatography-mass spectrometry.
Topics: Adolescent; Carnitine; Child; Child, Preschool; Chromatography, High Pressure Liquid; Humans; Isomerism; Male; Mass Spectrometry; Seizures; Valproic Acid | 1985 |
Recognition of medium-chain acyl-CoA dehydrogenase deficiency in asymptomatic siblings of children dying of sudden infant death or Reye-like syndromes.
Topics: Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenases; Adult; Breast Feeding; Carnitine; Child, Preschool; Female; Humans; Infant; Mass Spectrometry; Reye Syndrome; Risk; Sudden Infant Death | 1986 |
Diagnostic and therapeutic implications of medium-chain acylcarnitines in the medium-chain acyl-coA dehydrogenase deficiency.
Topics: Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenases; Carnitine; Dicarboxylic Acids; Female; Gas Chromatography-Mass Spectrometry; Humans; Infant; Male; Reye Syndrome | 1985 |
Octanoic acidemia and octanoylcarnitine excretion with dicarboxylic aciduria due to defective oxidation of medium-chain fatty acids.
Topics: Acyl-CoA Dehydrogenases; Caprylates; Carnitine; Cells, Cultured; Decanoic Acids; Dicarboxylic Acids; Fatty Acids; Fatty Acids, Nonesterified; Female; Fibroblasts; Humans; Infant; Lipid Metabolism, Inborn Errors; Male; Oxidation-Reduction | 1985 |
Octanoylglucuronide excretion in patients with a defective oxidation of medium-chain fatty acids.
Topics: Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenases; Caprylates; Carnitine; Fatty Acids; Gas Chromatography-Mass Spectrometry; Humans; Hydrogen-Ion Concentration; Lipid Metabolism, Inborn Errors | 1985 |
Studies with (plus)--octanoylcarnitine in experimental diabetic ketoacidosis.
Topics: Administration, Oral; Animals; Blood Glucose; Caproates; Caprylates; Carnitine; Depression, Chemical; Diabetes Mellitus, Experimental; Diabetic Ketoacidosis; Esters; Hemolysis; In Vitro Techniques; Injections, Intravenous; Insulin; Ketone Bodies; Liver; Male; Stimulation, Chemical | 1974 |
Urinary excretion of l-carnitine and acylcarnitines by patients with disorders of organic acid metabolism: evidence for secondary insufficiency of l-carnitine.
Topics: Acyl-CoA Dehydrogenases; Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids, Branched-Chain; Carnitine; Child; Child, Preschool; Female; Hemiterpenes; Humans; Infant; Infant, Newborn; Lysine; Male; Methylmalonic Acid; Middle Aged; Pentanoic Acids; Propionates | 1984 |
L-carnitine: therapeutic strategy for metabolic encephalopathy.
Topics: Animals; Biological Transport, Active; Brain Diseases; Caprylates; Carnitine; Choroid Plexus; In Vitro Techniques; Metabolic Diseases; Mitochondria; Rabbits | 1984 |
Effects of (+)-octanoylcarnitine on deoxyribonucleic acid synthesis in regenerating rabbit liver.
Topics: Animals; Caprylates; Carnitine; Depression, Chemical; DNA; Hepatectomy; Liver; Liver Regeneration; Male; Rabbits; Thymidine | 1982 |
Changes in predominant energy substrate after hepatectomy.
Topics: Adenine Nucleotides; Animals; Caprylates; Carnitine; Energy Metabolism; Fatty Acids, Nonesterified; Glucose; Hepatectomy; Ketone Bodies; Male; Mitochondria, Liver; Phosphorylation; Rabbits; Sodium Fluoride; Time Factors | 1981 |
Phosphoenolpyruvate synthesis by fetal guinea-pig liver mitochondria.
Topics: Animals; Animals, Newborn; Caprylates; Carnitine; Guinea Pigs; Ketoglutaric Acids; Malates; Mitochondria, Liver; Palmitoylcarnitine; Phosphoenolpyruvate; Succinates | 1981 |
Differences in predominant energy substrate in relation to the resected hepatic mass in the phase immediately after hepatectomy.
Topics: Animals; Caprylates; Carnitine; Energy Metabolism; Fatty Acids; Fatty Acids, Nonesterified; Glucose; Hepatectomy; Liver Regeneration; Male; Rabbits | 1981 |
The effects of energetic steady state, pyruvate concentration, and octanoyl-(--)-carnitine on the relative rates of carboxylation and decarboxylation of pyruvate by rat liver mitochondria.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Caprylates; Carnitine; Citric Acid Cycle; Kinetics; Mitochondria, Liver; Pyruvates; Pyruvic Acid; Rats | 1981 |
Is there a gloxylate cycle in the liver of the fetal guinea pig?
Topics: Animals; Caprylates; Carnitine; Citric Acid Cycle; Female; Fetus; Glucose; Glyoxylates; Guinea Pigs; Isocitrates; Liver; Oxygen Consumption; Palmitic Acids; Perfusion; Pregnancy | 1980 |
The effect of glucagon treatment and starvation of virgin and lactating rats on the rates of oxidation of octanoyl-L-carnitine and octanoate by isolated liver mitochondria.
Topics: Animals; Antimetabolites; Caprylates; Carnitine; Female; Glucagon; In Vitro Techniques; Kinetics; Lactation; Mitochondria, Liver; Oxidation-Reduction; Oxygen Consumption; Pregnancy; Rats; Starvation | 1980 |
Medium chain acyl-CoA dehydrogenase deficiency in Pennsylvania: neonatal screening shows high incidence and unexpected mutation frequencies.
Topics: Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenases; Amino Acid Sequence; Base Sequence; Carnitine; Cohort Studies; DNA; Female; Gene Deletion; Genetic Testing; Heterozygote; Humans; Incidence; Infant, Newborn; Male; Molecular Sequence Data; Mutation; Pennsylvania; Prospective Studies | 1995 |
Quantification of free carnitine, individual short- and medium-chain acylcarnitines, and total carnitine in plasma by high-performance liquid chromatography.
Topics: Acetylcarnitine; Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenases; Acylation; Carnitine; Chromatography, High Pressure Liquid; Humans; Methylmalonic Acid; Molecular Weight; Propionates; Reference Standards; Reproducibility of Results | 1993 |
Medium-chain acyl-CoA dehydrogenase (MCAD) deficiency: diagnosis by acylcarnitine analysis in blood.
Topics: Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenases; Carnitine; DNA Mutational Analysis; Female; Heterozygote; Homozygote; Humans; Infant; Infant, Newborn; Lipid Metabolism, Inborn Errors; Male; Mass Spectrometry; Predictive Value of Tests; Reproducibility of Results | 1993 |
Detection of inborn errors of fatty acid oxidation from acylcarnitine analysis of plasma and blood spots with the radioisotopic exchange-high-performance liquid chromatographic method.
Topics: Acyl-CoA Dehydrogenase; Carnitine; Chromatography, High Pressure Liquid; Fatty Acid Desaturases; Humans; Lipid Metabolism, Inborn Errors | 1993 |
Effects of fatty acids and ketone bodies on cytochromes P450 2B, 4A, and 2E1 expression in primary cultured rat hepatocytes.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Carnitine; Cells, Cultured; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Decanoic Acids; Enzyme Inhibitors; Fatty Acids; Fatty Acids, Unsaturated; Glycerol; Hydroxybutyrates; Ketone Bodies; Liver; Mixed Function Oxygenases; Palmitates; Pyruvic Acid; Rats; RNA, Messenger; Triazoles | 1997 |
Rapid diagnosis of MCAD deficiency: quantitative analysis of octanoylcarnitine and other acylcarnitines in newborn blood spots by tandem mass spectrometry.
Topics: Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenases; Butanols; Carnitine; Humans; Infant, Newborn; Mass Spectrometry; Prospective Studies; Radioisotope Dilution Technique; Reproducibility of Results; Time Factors | 1997 |
Blood-brain barrier controls carnitine level in the brain: a study on a model system with RBE4 cells.
Topics: Acetylcarnitine; Animals; Betaine; Blood-Brain Barrier; Brain; Carnitine; Cell Line; Cell Membrane; Cerebrovascular Circulation; Endothelium, Vascular; Kinetics; Microcirculation; Models, Biological; Rats | 2000 |
Different sensitivity of rabbit heart and skeletal muscle to endotoxin-induced impairment of mitochondrial function.
Topics: Animals; Carnitine; Cell Respiration; Electron Transport; Female; Heart; In Vitro Techniques; Lipopolysaccharides; Male; Mitochondria, Muscle; Muscle Fibers, Skeletal; Muscle, Skeletal; Myocardium; Organ Specificity; Perfusion; Pyruvic Acid; Rabbits; Saponins; Sepsis; Specimen Handling; Succinic Acid; Time Factors; Vascular Resistance | 2001 |
Errors caused by the use of D,L-octanoylcarnitine for blood-spot calibrators.
Topics: Blood Specimen Collection; Calibration; Carnitine; Humans; Indicators and Reagents; Infant, Newborn; Mass Spectrometry; Paper; Stereoisomerism | 2001 |
A polymeric microfluidic chip for CE/MS determination of small molecules.
Topics: Acetylcarnitine; Carnitine; Electrophoresis, Capillary; Microscopy, Electron, Scanning; Molecular Structure; Polymers; Spectrometry, Mass, Electrospray Ionization | 2001 |
Evaluation of newborn screening for medium chain acyl-CoA dehydrogenase deficiency in 275 000 babies.
Topics: Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenases; Australian Capital Territory; Carnitine; Humans; Infant, Newborn; Mass Spectrometry; Mutation; Neonatal Screening; New South Wales; Prospective Studies; Retrospective Studies | 2001 |
Neonatal screening for medium-chain acyl-CoA dehydrogenase deficiency.
Topics: Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenases; Carnitine; Humans; Infant, Newborn; Neonatal Screening; Retrospective Studies; United Kingdom | 2001 |
Relevance of fatty acid oxidation in regulation of the outer mitochondrial membrane permeability for ADP.
Topics: Adenosine Diphosphate; Animals; Biological Transport; Carnitine; Fatty Acids; Intracellular Membranes; Male; Mitochondria, Heart; Oxidative Phosphorylation; Oxygen Consumption; Palmitoyl Coenzyme A; Palmitoylcarnitine; Permeability; Rats | 2001 |
Blood acylcarnitine levels in normal newborns and heterozygotes for medium-chain acyl-CoA dehydrogenase deficiency: a relationship between genotype and biochemical phenotype?
Topics: Acyl-CoA Dehydrogenase; Adenine; Carnitine; Diagnosis, Differential; Gene Frequency; Genotype; Guanine; Heterozygote; Humans; Infant, Low Birth Weight; Infant, Newborn; Metabolism, Inborn Errors; Osmolar Concentration; Phenotype | 2004 |
Crystal structure of mouse carnitine octanoyltransferase and molecular determinants of substrate selectivity.
Topics: Amino Acid Sequence; Animals; Binding Sites; Carnitine; Carnitine Acyltransferases; Catalysis; Crystallography, X-Ray; Mice; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; Sequence Alignment; Substrate Specificity | 2005 |
Na+, K+ ATPase activity is markedly reduced by cis-4-decenoic acid in synaptic plasma membranes from cerebral cortex of rats.
Topics: Acyl-CoA Dehydrogenase; Animals; Antioxidants; Carnitine; Cerebral Cortex; Enzyme Inhibitors; Fatty Acids, Monounsaturated; Lipid Peroxidation; Luminescent Measurements; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Synaptic Membranes; Thiobarbituric Acid Reactive Substances | 2006 |
Biomarker discovery, disease classification, and similarity query processing on high-throughput MS/MS data of inborn errors of metabolism.
Topics: Acyl-CoA Dehydrogenase; Biomarkers; Carnitine; Case-Control Studies; Humans; Mass Spectrometry; Metabolism, Inborn Errors; Methylmalonic Acid | 2006 |
Spectrum of medium-chain acyl-CoA dehydrogenase deficiency detected by newborn screening.
Topics: Acyl-CoA Dehydrogenase; Biomarkers; Breast Feeding; Carnitine; Humans; Infant Formula; Infant, Newborn; Neonatal Screening; Point Mutation; Sequence Analysis, DNA | 2008 |
Dissection of biochemical borderline phenotypes in carriers and genetic variants of medium-chain acyl-CoA dehyrogenase deficiency: implications for newborn screening [corrected].
Topics: Carnitine; Case-Control Studies; Heterozygote; Humans; Infant, Newborn; Lipid Metabolism, Inborn Errors; Mutation; Neonatal Screening | 2009 |
Lack of genotype-phenotype correlations and outcome in MCAD deficiency diagnosed by newborn screening in New York State.
Topics: Acyl-CoA Dehydrogenases; Carnitine; Fatty Acids; Female; Genotype; Humans; Infant, Newborn; Male; Metabolism, Inborn Errors; Mutation; Neonatal Screening; New York; Phenotype; Prognosis | 2010 |
Comparison of amino acids and acylcarnitines assay methods used in newborn screening assays by tandem mass spectrometry.
Topics: Amino Acids; Butanols; Carnitine; Humans; Infant, Newborn; Leucine; Metabolic Diseases; Methionine; Neonatal Screening; Palmitoylcarnitine; Phenylalanine; Quality Control; Tandem Mass Spectrometry | 2010 |
Relationship of octanoylcarnitine concentrations to age at sampling in unaffected newborns screened for medium-chain acyl-CoA dehydrogenase deficiency.
Topics: Acyl-CoA Dehydrogenase; Age Factors; Amino Acid Metabolism, Inborn Errors; Australia; Carnitine; England; Female; Humans; Infant, Newborn; Male | 2010 |
Mitochondrial respiration in subcutaneous and visceral adipose tissue from patients with morbid obesity.
Topics: Adult; Biopsy; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Carnitine; Cell Respiration; DNA, Mitochondrial; Energy Metabolism; Female; Glutamic Acid; Humans; Intra-Abdominal Fat; Malates; Male; Microscopy, Electron, Transmission; Mitochondria; Obesity, Morbid; Omentum; Oxidative Phosphorylation; Subcutaneous Fat, Abdominal; Succinic Acid; Time Factors; Uncoupling Agents | 2010 |
Allelic diversity in MCAD deficiency: the biochemical classification of 54 variants identified during 5 years of ACADM sequencing.
Topics: Acyl-CoA Dehydrogenase; Adolescent; Adult; Alleles; Carnitine; Child; Child, Preschool; DNA Mutational Analysis; Exons; Genetic Association Studies; Genetic Carrier Screening; Genetic Variation; Genotype; Glycine; Humans; Infant, Newborn; Lipid Metabolism, Inborn Errors; Middle Aged; Mutation; Mutation, Missense; Neonatal Screening; Polymorphism, Single Nucleotide; Young Adult | 2010 |
Increased mitochondrial substrate sensitivity in skeletal muscle of patients with type 2 diabetes.
Topics: Carnitine; Case-Control Studies; Cell Respiration; Citrate (si)-Synthase; Diabetes Mellitus, Type 2; Glutamic Acid; Humans; Insulin Resistance; Male; Middle Aged; Mitochondria, Muscle; Muscle, Skeletal; Myosin Heavy Chains; Obesity; Substrate Specificity; Succinic Acid; Superoxide Dismutase; Thinness | 2011 |
Disruption of redox homeostasis in cerebral cortex of developing rats by acylcarnitines accumulating in medium-chain acyl-CoA dehydrogenase deficiency.
Topics: Acyl-CoA Dehydrogenase; alpha-Tocopherol; Animals; Carnitine; Cerebral Cortex; Glutathione; Homeostasis; Lipid Metabolism, Inborn Errors; Lipid Peroxidation; Male; Melatonin; Oxidative Stress; Protein Carbonylation; Rats; Rats, Wistar; Statistics, Nonparametric; Thiobarbituric Acid Reactive Substances | 2012 |
Decreased mitochondrial oxidative phosphorylation capacity in the human heart with left ventricular systolic dysfunction.
Topics: Aged; Biopsy; Carnitine; Creatine; Creatine Kinase, Mitochondrial Form; Energy Metabolism; Fatty Acids; Female; Heart Failure, Systolic; Heart Valve Prosthesis Implantation; Heart-Assist Devices; Humans; Male; Middle Aged; Mitochondria, Heart; Mitochondrial Diseases; Myocardium; Oxidative Phosphorylation; Reference Values; Stroke Volume; Ventricular Dysfunction, Left | 2013 |
Characterization of Pseudomonas aeruginosa growth on O-acylcarnitines and identification of a short-chain acylcarnitine hydrolase.
Topics: Blotting, Western; Carboxylic Ester Hydrolases; Carnitine; Computational Biology; DNA Primers; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Genetic Vectors; Hydrolysis; Polymerase Chain Reaction; Pseudomonas aeruginosa; Type C Phospholipases | 2013 |
Maternal and cord blood LC-HRMS metabolomics reveal alterations in energy and polyamine metabolism, and oxidative stress in very-low birth weight infants.
Topics: Biogenic Polyamines; Carnitine; Female; Fetal Blood; Gestational Age; Glutamic Acid; Glutamine; Humans; Infant; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Male; Maternal-Fetal Exchange; Pregnancy | 2013 |
Identification and assay of underivatized urinary acylcarnitines by paper spray tandem mass spectrometry.
Topics: Adult; Calibration; Carnitine; Humans; Limit of Detection; Paper; Reproducibility of Results; Tandem Mass Spectrometry; Young Adult | 2013 |
Quantification of plasma carnitine and acylcarnitines by high-performance liquid chromatography-tandem mass spectrometry using online solid-phase extraction.
Topics: Acetylcarnitine; Carnitine; Chromatography, High Pressure Liquid; Humans; Limit of Detection; Methanol; Palmitoylcarnitine; Reproducibility of Results; Solid Phase Extraction | 2013 |
The effect of high-intensity training on mitochondrial fat oxidation in skeletal muscle and subcutaneous adipose tissue.
Topics: Adult; Carnitine; Exercise; Female; Humans; Male; Mitochondria; Mitochondria, Muscle; Muscle, Skeletal; Overweight; Oxidative Phosphorylation; Oxygen Consumption; Palmitoylcarnitine; Subcutaneous Fat | 2015 |
Continuous-flow microelectroextraction for enrichment of low abundant compounds.
Topics: Carnitine; Chromatography, Reverse-Phase; Electrochemical Techniques; Equipment Design; Humans; Laurates; Limit of Detection; Mass Spectrometry; Solid Phase Extraction | 2014 |
The impact of ageing on adipose structure, function and vasculature in the B6D2F1 mouse: evidence of significant multisystem dysfunction.
Topics: Adipose Tissue; Aging; Animals; Arteries; Body Weight; Carnitine; Glutamic Acid; Malates; Male; Mice; Mitochondria; Neovascularization, Physiologic; Oxidative Stress; Oxygen Consumption; Succinic Acid; Triglycerides; Tyrosine; Vasodilation | 2014 |
Newborn screening for medium chain acyl-CoA dehydrogenase deficiency: performance improvement by monitoring a new ratio.
Topics: Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenases; Biomarkers; Carnitine; False Positive Reactions; Heterozygote; Humans; Infant; Infant, Newborn; Infant, Very Low Birth Weight; Lipid Metabolism, Inborn Errors; Neonatal Screening; United States | 2014 |
Association between arterial stiffness and serum L-octanoylcarnitine and lactosylceramide in overweight middle-aged subjects: 3-year follow-up study.
Topics: Adult; Antigens, CD; Blood Pressure; Body Mass Index; Carnitine; Case-Control Studies; Humans; Lactosylceramides; Leucine; Middle Aged; Overweight; Vascular Stiffness | 2015 |
Newborn screening blood spot analysis in the UK: influence of spot size, punch location and haematocrit.
Topics: Amino Acids; Blood Specimen Collection; Carnitine; Dried Blood Spot Testing; Heel; Hematocrit; Humans; Infant, Newborn; Leucine; Linear Models; Methionine; Neonatal Screening; Phenylalanine; Thyrotropin; Trypsinogen; Tyrosine; United Kingdom | 2016 |
Altered Oxygen Utilisation in Rat Left Ventricle and Soleus after 14 Days, but Not 2 Days, of Environmental Hypoxia.
Topics: Animals; Carnitine; Carnitine O-Palmitoyltransferase; Energy Metabolism; Gene Expression; Heart Ventricles; Hypoxia; Immunoblotting; Ion Channels; Male; Mitochondria, Muscle; Mitochondrial Proteins; Muscle, Skeletal; Myocardium; Oxidation-Reduction; Oxidative Phosphorylation; Oxygen; Oxygen Consumption; PPAR alpha; Pyruvic Acid; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Uncoupling Protein 3 | 2015 |
Low levels of short- and medium-chain acylcarnitines in HIV-infected patients.
Topics: Adult; Antiretroviral Therapy, Highly Active; Carnitine; Case-Control Studies; Disease Progression; Female; HIV Infections; Humans; Interferon-gamma; Interferon-gamma Release Tests; Longitudinal Studies; Male; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Tumor Necrosis Factor-alpha | 2016 |
Inhibition of β-oxidation is not a valid therapeutic tool for reducing oxidative stress in conditions of neurodegeneration.
Topics: Animals; Brain; Caprylates; Carnitine; Energy Metabolism; Homeostasis; Neurodegenerative Diseases; Oxidation-Reduction; Oxidative Stress; Rats | 2017 |
Correcting false positive medium-chain acyl-CoA dehydrogenase deficiency results from newborn screening; synthesis, purification, and standardization of branched-chain C8 acylcarnitines for use in their selective and accurate absolute quantitation by UHPL
Topics: Acyl-CoA Dehydrogenase; Carnitine; Chromatography, High Pressure Liquid; False Positive Reactions; Humans; Infant, Newborn; Lipid Metabolism, Inborn Errors; Neonatal Screening; Sensitivity and Specificity; Tandem Mass Spectrometry | 2017 |
Elevated Medium-Chain Acylcarnitines Are Associated With Gestational Diabetes Mellitus and Early Progression to Type 2 Diabetes and Induce Pancreatic β-Cell Dysfunction.
Topics: Adult; Animals; Carnitine; Case-Control Studies; Cell Respiration; Diabetes Mellitus, Type 2; Diabetes, Gestational; Disease Progression; Female; Glucose Intolerance; Humans; Insulin; Insulin Secretion; Insulin-Secreting Cells; Islets of Langerhans; Mice; Postpartum Period; Pregnancy | 2018 |
Medium-Chain Acylcarnitines Are Associated With Cardioembolic Stroke and Stroke Recurrence.
Topics: Aged; Biomarkers; Brain Ischemia; Carnitine; Chromatography, Liquid; Female; Humans; Male; Metabolomics; Middle Aged; Recurrence; Stroke; Tandem Mass Spectrometry | 2018 |
A nationwide retrospective observational study of population newborn screening for medium-chain acyl-CoA dehydrogenase (MCAD) deficiency in the Netherlands.
Topics: Acyl-CoA Dehydrogenase; Carnitine; Female; Genotype; Humans; Infant, Newborn; Lipid Metabolism, Inborn Errors; Male; Neonatal Screening; Netherlands; Prevalence; Retrospective Studies | 2019 |
Medium-chain acyl-coenzyme A dehydrogenase deficiency: Six cases in the Chinese population.
Topics: Acyl-CoA Dehydrogenase; Biomarkers; Carnitine; Child, Preschool; China; Female; Genetic Markers; Humans; Infant; Infant, Newborn; Lipid Metabolism, Inborn Errors; Male; Mutation; Neonatal Screening | 2019 |
Plasma metabolites as possible biomarkers for diagnosis of breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Breast Neoplasms; Carnitine; Case-Control Studies; Chromatography, Liquid; Docosahexaenoic Acids; Female; Humans; Hypoxanthine; Mass Spectrometry; Metabolomics; Middle Aged; Pyrrolidonecarboxylic Acid | 2019 |
Preoperative plasma fatty acid metabolites inform risk of prostate cancer progression and may be used for personalized patient stratification.
Topics: Aged; Carnitine; Case-Control Studies; Chromatography, Liquid; Disease Progression; Fatty Acids; Humans; Male; Mass Spectrometry; Metabolomics; Middle Aged; Prognosis; Prostatic Neoplasms; White People | 2019 |
The association between newborn screening analytes as measured on a second screen and childhood autism in a Texas Medicaid population.
Topics: Acetylcarnitine; Autism Spectrum Disorder; Autistic Disorder; Biomarkers; Carnitine; Case-Control Studies; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Male; Neonatal Screening; Odds Ratio; Texas | 2020 |
Early pregnancy metabolites predict gestational diabetes mellitus: implications for fetal programming.
Topics: Adult; Alanine; Arginine; Carnitine; Case-Control Studies; Diabetes, Gestational; Diet Therapy; Dopamine; Early Diagnosis; Epigenesis, Genetic; Female; Fetal Development; Gestational Age; Glucose Tolerance Test; Glucuronides; Humans; Hypoglycemic Agents; Lactones; Lysine; Meglutol; Metabolomics; Neopterin; Orotic Acid; Phenols; Pregnancy; Ribonucleosides; Sulfides | 2021 |
Newborn screening and genetic variation of medium chain acyl-CoA dehydrogenase deficiency in the Chinese population.
Topics: Acyl-CoA Dehydrogenase; Carnitine; China; Fatty Acids; Genetic Variation; Humans; Infant, Newborn; Lipid Metabolism, Inborn Errors; Neonatal Screening; Retrospective Studies; Tandem Mass Spectrometry | 2022 |