Compounds > carnitine

carnitine and malonyl coenzyme a

carnitine has been researched along with malonyl coenzyme a in 71 studies

Research

Studies (71)

TimeframeStudies, this research(%)All Research%
pre-199018 (25.35)18.7374
1990's12 (16.90)18.2507
2000's26 (36.62)29.6817
2010's13 (18.31)24.3611
2020's2 (2.82)2.80

Authors

AuthorsStudies
Foster, DW; Mannaerts, GP; McGarry, JD1
Nozu, F; Takeyama, N; Tanaka, T1
Chiodi, P; Maccari, F; Ramacci, MT1
Allen, RH; Brass, EP; Ruff, LJ; Stabler, SP1
Kitazawa, Y; Matsuo, N; Takagi, D; Takeyama, N; Tanaka, T1
Dubelaar, ML; Hulsmann, WC; Luyt-Houwen, IE; Scholte, HR1
Bezard, J; Cao Danh, H; Clouet, P; Henninger, C; Pascal, M1
Bieber, LL; Fiol, CJ; Kerner, J1
Brady, LJ; Brady, PS1
Deaciuc, IV; Kuhnle, HF; Schmidt, FH1
Grantham, BD; Zammit, VA1
Bird, MI; Saggerson, ED1
Van Moerkerk, HT; Veerkamp, JH1
Beattie, MA; Winder, WW1
Foster, DW2
Foster, DW; McGarry, JD1
Paulson, DJ; Shug, AL; Ward, KM1
Bieber, LL; Fiol, CJ1
Foster, DW; Long, CS; McGarry, JD; Mills, SE1
Zammit, VA2
Gamble, J; Lopaschuk, GD1
Rodnick, KJ; Sidell, BD1
Allard, MF; Lopaschuk, GD; Schönekess, BO1
Bieber, LL; Wagner, M1
Arvidson, DN; Cregg, JM; de Vries, Y; Shi, J; Woldegiorgis, G; Zhu, H1
Abdel-aleem, S; El-Dawy, K; El-Shewy, HM; Hendrickson, SC; Lowe, JE; St Louis, J; Taylor, DA1
Adams, SH; Brown, NF; Esser, V; Foster, DW; Ing, NH; Johnson, L; McGarry, JD1
Elliott, KR; Krauss, S; New, KJ; Quant, PA1
Gellerich, FN; Hein, W; Hertel, K; Zierz, S1
Cameron, JM; Fraser, F; Jackson, VN; Price, NT; Zammit, VA1
Hoppel, C; Kerner, J1
Chien, D; Dean, D; Flatt, JP; Ruderman, NB; Saha, AK1
Jackson, VN; Price, NT; Zammit, VA2
Fraser, F; Padovese, R; Zammit, VA1
Guertl, B; Hoefler, G; Noehammer, C1
Haro, D; Hegardt, FG; Marrero, PF; Nicot, C; Woldegiorgis, G1
Dagher, Z; Ido, Y; Ruderman, N; Tornheim, K1
Clayton, CA; Heigenhauser, GJ; Mercado, AJ; Richards, JG; Wood, CM1
Campbell, FM; Dyck, JR; Hopkins, TA; Lopaschuk, GD; Onay Besikci, A; Onay-Besikci, A1
Dai, J; Haro, D; Marrero, PF; Napal, L; Treber, M; Woldegiorgis, G1
Kiens, B; Roepstorff, C1
Gellerich, FN; Traufeller, K; Zierz, S1
Halberg, N; Hillig, T; Kiens, B; Richter, EA; Roepstorff, C; Ruderman, NB; Saha, AK; Wojtaszewski, JF1
Gacias, M; Haro, D; Marrero, PF; Nicot, C; Relat, J; Woldegiorgis, G1
Calvani, M; Grippo, P; Margarucci, S; Melone, MA; Peluso, G; Petillo, O; Tuccillo, F1
Dai, J; Liu, H; Treber, M; Woldegiorgis, G; Zheng, G1
Asaumi, M; Cha, SH; Dai, Y; Kurama, T; Lane, MD; Matsumoto, S; Shimokawa, T; Suwa, A; Wolfgang, MJ1
Asins, G; Bentebibel, A; de Arriaga, D; Gómez-Puertas, P; Gurunathan, C; Hegardt, FG; López-Viñas, E; Morillas, M; Serra, D1
Alexandre, A; Bortolami, S; Cavallini, L; Comelato, E; Zoccarato, F1
Hoppel, CL; Kerner, J; Minkler, PE; Parland, WK1
Haro, D; Marrero, PF; Pujol-Vidal, M; Relat, J1
Ide, T; Lim, JS; Nakashima, Y; Odbayar, TO1
Downs, SM; Klinger, J; Mosey, JL1
Albaugh, VL; Breazeale, S; Elich, TD; Ilkayeva, O; Joyal, JL; Lang, CH; Lynch, CJ; Maresca, KP; Vary, TC; Wenner, BR1
Bell, JA; Cree, MG; Dohm, GL; Ilkayeva, O; Koves, TR; Muoio, DM; Tapscott, EB; Thyfault, JP; Wolfe, RR1
Burch, M; Cleary, MA; Dixon, M; Footitt, EJ; Jakobs, C; Salomons, GS; Stafford, J1
Dudkiewicz, Z; Hozyasz, KK; Oltarzewski, M1
Garcia-Menendez, L; Kolwicz, SC; Marney, LC; Olson, DP; Synovec, RE; Tian, R1
Grenier, MA; Huth, CM; Jefferies, JL; Leslie, ND; Page, KI; Prada, CE; Spicer, RL; Towbin, JA1
Holloway, GP; Koves, TR; Muoio, DM; Neufer, PD; Perry, CG; Smith, BK; Smith, JC; Wright, DC1
Casals, N; Gao, S; Keung, W; Lopaschuk, GD; Moran, TH1
Gao, S; Hegardt, FG; Keung, W; Lopaschuk, GD; Serra, D1
Al-Harbi, MM; Al-Harbi, NO; Al-Hosaini, KA; Al-Shabanah, OA; Al-Sharary, SD; Aldelemy, ML; Hafez, MM; Sayed-Ahmed, MM1
Gao, X; Gong, Z; Gu, X; Han, L; Jin, J; Qiu, W; Wang, Y; Wu, S; Ye, J; Zhang, H1
Ali, SF; Bauermann, O; Binienda, ZK; Diedenhofen, A; Pinto, L; van der Leij, FR; Virmani, A; Zerelli, S1
Abdullah, ML; Al-Shabanah, OA; Alrikabi, A; Alrufaiq, BI; Hafez, MM; Sayed-Ahmed, MM1
Joshi, PR; Zierz, S1
Abily-Donval, L; Bekri, S; Goldenberg, A; Marret, S; Salomons, GS; Snanoudj, S; Sudrié-Arnaud, B; Tebani, A; Torre, S1

Reviews

8 review(s) available for carnitine and malonyl coenzyme a

ArticleYear
Banting lecture 1984. From glycogen to ketones--and back.
    Diabetes, 1984, Volume: 33, Issue:12

    Topics: Animals; Carnitine; Carnitine O-Palmitoyltransferase; Fasting; Fatty Acids; Food; Fructosediphosphates; Glucagon; Glucose-6-Phosphatase; Humans; Insulin Antibodies; Ketone Bodies; Liver; Liver Glycogen; Malonyl Coenzyme A; Models, Biological; Perfusion; Phosphorylation

1984
Regulation of hepatic fatty acid oxidation and ketone body production.
    Annual review of biochemistry, 1980, Volume: 49

    Topics: Acetyl Coenzyme A; Adipose Tissue; Animals; Carnitine; Carnitine Acyltransferases; Fatty Acids; Fatty Acids, Nonesterified; Glucagon; Glycogen; Insulin; Ketone Bodies; Liver; Malonyl Coenzyme A; Meglutol; Models, Biological; Triglycerides

1980
The 1993 Merck Frosst Award. Acetyl-CoA carboxylase: an important regulator of fatty acid oxidation in the heart.
    Canadian journal of physiology and pharmacology, 1994, Volume: 72, Issue:10

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Animals; Carbohydrate Metabolism; Carnitine; Carnitine O-Palmitoyltransferase; Diabetes Mellitus; Down-Regulation; Fatty Acids; Humans; Malonyl Coenzyme A; Mitochondria, Heart; Myocardial Ischemia; Oxidation-Reduction

1994
Fatty acid import into mitochondria.
    Biochimica et biophysica acta, 2000, Jun-26, Volume: 1486, Issue:1

    Topics: Animals; Binding Sites; Biological Transport; Carnitine; Carnitine O-Palmitoyltransferase; Coenzyme A Ligases; Fatty Acids; Gene Expression Regulation, Enzymologic; Humans; Intracellular Membranes; Malonyl Coenzyme A; Mitochondria; Oxidation-Reduction; Porins; Repressor Proteins; Saccharomyces cerevisiae Proteins; Structure-Activity Relationship

2000
Metabolic cardiomyopathies.
    International journal of experimental pathology, 2000, Volume: 81, Issue:6

    Topics: Adult; Animals; Calcium; Cardiomegaly; Cardiomyopathies; Cardiomyopathy, Alcoholic; Carnitine; Diabetes Mellitus; Fatty Acids; Glucose; Heart Failure; Humans; Lysosomal Storage Diseases; Malonyl Coenzyme A; Mitochondrial Myopathies; Mucopolysaccharidoses; Myocardium; Oxidative Phosphorylation

2000
Utilization of long-chain fatty acids in human skeletal muscle during exercise.
    Acta physiologica Scandinavica, 2003, Volume: 178, Issue:4

    Topics: Biological Transport, Active; Carnitine; Cell Membrane; Energy Metabolism; Exercise; Fatty Acids; Humans; Male; Malonyl Coenzyme A; Mitochondria; Muscle, Skeletal; Oxidation-Reduction; Physical Endurance

2003
The role of the carnitine system in human metabolism.
    Annals of the New York Academy of Sciences, 2004, Volume: 1033

    Topics: Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Carnitine; Carnitine O-Palmitoyltransferase; DNA-Binding Proteins; Fatty Acids; Glucose; Humans; Intracellular Signaling Peptides and Proteins; Ketones; Liver; Malonyl Coenzyme A; Membrane Proteins; Mice; Oxidation-Reduction; PPAR gamma; Stearoyl-CoA Desaturase; Transcription Factors

2004
Muscle Carnitine Palmitoyltransferase II (CPT II) Deficiency: A Conceptual Approach.
    Molecules (Basel, Switzerland), 2020, Apr-13, Volume: 25, Issue:8

    Topics: Carnitine; Carnitine O-Palmitoyltransferase; Fatty Acids; Female; Genetic Association Studies; Humans; Male; Malonyl Coenzyme A; Metabolism, Inborn Errors; Mitochondria; Muscle, Skeletal; Oxidation-Reduction

2020

Other Studies

63 other study(ies) available for carnitine and malonyl coenzyme a

ArticleYear
Characteristics of fatty acid oxidation in rat liver homogenates and the inhibitory effect of malonyl-CoA.
    Biochimica et biophysica acta, 1978, Sep-28, Volume: 530, Issue:3

    Topics: Acyl Coenzyme A; Animals; Caprylates; Carnitine; Kidney Cortex; Male; Malonyl Coenzyme A; Mitochondria, Liver; Myocardium; Oleic Acids; Rats

1978
Changes of hepatic fatty acid metabolism produced by chronic thioacetamide administration in rats.
    Hepatology (Baltimore, Md.), 1992, Volume: 15, Issue:6

    Topics: Animals; Carnitine; Carnitine O-Palmitoyltransferase; Fatty Acids; Ketone Bodies; Liver; Liver Cirrhosis, Experimental; Male; Malonyl Coenzyme A; Mitochondria, Liver; Oxidation-Reduction; Oxygen; Palmitoyl Coenzyme A; Palmitoylcarnitine; Rats; Rats, Inbred Strains; Thioacetamide; Time Factors

1992
Tissue lipid accumulation by L-aminocarnitine, an inhibitor of carnitine-palmitoyltransferase-2. Studies in intact rats and isolated mitochondria.
    Biochimica et biophysica acta, 1992, Jul-09, Volume: 1127, Issue:1

    Topics: Animals; Betaine; Carnitine; Carnitine O-Palmitoyltransferase; Cholesterol; Female; Lipid Metabolism; Malonyl Coenzyme A; Mitochondria, Liver; Oxidation-Reduction; Palmitoylcarnitine; Phospholipids; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Succinates; Succinic Acid; Triglycerides

1992
Effect of hydroxycobalamin[c-lactam] on propionate and carnitine metabolism in the rat.
    The Biochemical journal, 1990, Mar-15, Volume: 266, Issue:3

    Topics: Acyl Coenzyme A; Animals; Carnitine; Hydroxocobalamin; Lactams; Liver; Male; Malonates; Malonyl Coenzyme A; Propionates; Rats; Vitamin B 12 Deficiency

1990
Altered hepatic fatty acid metabolism in endotoxicosis: effect of L-carnitine on survival.
    The American journal of physiology, 1989, Volume: 256, Issue:1 Pt 1

    Topics: Animals; Carnitine; Carnitine O-Acetyltransferase; Carnitine O-Palmitoyltransferase; Coenzyme A; Coenzyme A Ligases; Escherichia coli; Esterification; Fatty Acids; Ketone Bodies; Lipopolysaccharides; Liver; Male; Malonyl Coenzyme A; Oxidation-Reduction; Rats; Rats, Inbred Strains; Repressor Proteins; Saccharomyces cerevisiae Proteins; Shock, Septic

1989
The source of malonyl-CoA in rat heart. The calcium paradox releases acetyl-CoA carboxylase and not propionyl-CoA carboxylase.
    FEBS letters, 1986, Mar-17, Volume: 198, Issue:1

    Topics: Acetyl-CoA Carboxylase; Acyl Coenzyme A; Animals; Calcium; Carboxy-Lyases; Carnitine; Carnitine O-Palmitoyltransferase; Ligases; Male; Malonyl Coenzyme A; Methylmalonyl-CoA Decarboxylase; Myocardium; Rats; Rats, Inbred Strains

1986
Effects of fenofibrate treatment on fatty acid oxidation in liver mitochondria of obese Zucker rats.
    Biochemical pharmacology, 1987, Oct-01, Volume: 36, Issue:19

    Topics: Animals; Carnitine; Carnitine O-Acetyltransferase; Fatty Acids; Fenofibrate; Hypolipidemic Agents; Male; Malonyl Coenzyme A; Mitochondria, Liver; Oxidation-Reduction; Palmitoyl Coenzyme A; Propionates; Rats; Rats, Zucker

1987
Effect of malonyl-CoA on the kinetics and substrate cooperativity of membrane-bound carnitine palmitoyltransferase of rat heart mitochondria.
    Biochimica et biophysica acta, 1987, Dec-18, Volume: 916, Issue:3

    Topics: Acyl Coenzyme A; Acyltransferases; Animals; Carnitine; Carnitine O-Palmitoyltransferase; Fasting; Kinetics; Malonyl Coenzyme A; Membranes; Mitochondria, Heart; Mitochondrial Swelling; Rats; Substrate Specificity

1987
Action in vivo and in vitro of 2-tetradecylglycidic acid, 2-tetradecylglycidyl-CoA and 2-tetradecylglycidylcarnitine on hepatic carnitine palmitoyltransferase.
    The Biochemical journal, 1986, Sep-15, Volume: 238, Issue:3

    Topics: Acyl Coenzyme A; Acyltransferases; Administration, Oral; Animals; Azetidines; Carnitine; Carnitine O-Palmitoyltransferase; Epoxy Compounds; Ethers, Cyclic; Fatty Acids; Female; Fluorescence Polarization; Hypoglycemic Agents; In Vitro Techniques; Kinetics; Liver; Male; Malonyl Coenzyme A; Mitochondria, Liver; Palmitoyl Coenzyme A; Rats; Rats, Inbred Strains

1986
A new inhibitor of the long-chain fatty acid transfer across the mitochondrial membrane: 2-(3-methylcinnamylhydrazono)-propionate (BM 42.304).
    Life sciences, 1985, Jan-07, Volume: 36, Issue:1

    Topics: Acyltransferases; Animals; Biological Transport; Carnitine; Carnitine Acyltransferases; Carnitine O-Palmitoyltransferase; Cinnamates; Epoxy Compounds; Fatty Acids; Guinea Pigs; Hypoglycemic Agents; Intracellular Membranes; Kinetics; Male; Malonyl Coenzyme A; Mitochondria, Liver; Palmitoylcarnitine; Transferases

1985
Binding of [14C]malonyl-CoA to rat liver mitochondria after blocking of the active site of carnitine palmitoyltransferase I. Displacement of low-affinity binding by palmitoyl-CoA.
    The Biochemical journal, 1986, Jan-15, Volume: 233, Issue:2

    Topics: Acyl Coenzyme A; Acyltransferases; Animals; Binding Sites; Carnitine; Carnitine O-Palmitoyltransferase; Coenzyme A; Isoenzymes; Malonyl Coenzyme A; Mitochondria, Liver; Palmitoyl Coenzyme A; Rats

1986
Interacting effects of L-carnitine and malonyl-CoA on rat liver carnitine palmitoyltransferase.
    The Biochemical journal, 1985, Aug-15, Volume: 230, Issue:1

    Topics: Acyl Coenzyme A; Acyltransferases; Animals; Carnitine; Carnitine O-Palmitoyltransferase; Kinetics; Male; Malonyl Coenzyme A; Mitochondria, Heart; Mitochondria, Liver; Palmitoyl Coenzyme A; Rats; Rats, Inbred Strains; Starvation

1985
Effect of various agents and conditions on palmitate oxidation by homogenates of rat liver and rat and human skeletal muscle.
    The International journal of biochemistry, 1985, Volume: 17, Issue:11

    Topics: Animals; Antimycin A; Betaine; Carbon Radioisotopes; Carnitine; Clofibric Acid; Cyanates; Fatty Acids; Humans; Liver; Malonyl Coenzyme A; Mitochondria, Liver; Mitochondria, Muscle; Muscles; Oxidation-Reduction; Palmitic Acid; Palmitic Acids; Rats

1985
Mechanism of training-induced attenuation of postexercise ketosis.
    The American journal of physiology, 1984, Volume: 247, Issue:5 Pt 2

    Topics: 3-Hydroxybutyric Acid; Acidosis; Animals; Carnitine; Cyclic AMP; Hydroxybutyrates; Ketosis; Liver; Liver Glycogen; Male; Malonyl Coenzyme A; Physical Conditioning, Animal; Physical Endurance; Physical Exertion; Rats; Rats, Inbred Strains

1984
Malonyl CoA inhibition of carnitine palmityltransferase in rat heart mitochondria.
    FEBS letters, 1984, Oct-29, Volume: 176, Issue:2

    Topics: Acyl Coenzyme A; Acyltransferases; Animals; Carnitine; Carnitine O-Palmitoyltransferase; Fasting; Malates; Malonyl Coenzyme A; Mitochondria, Heart; Mitochondrial ADP, ATP Translocases; Oxygen Consumption; Palmitoyl Coenzyme A; Pyruvates; Pyruvic Acid; Rats

1984
Sigmoid kinetics of purified beef heart mitochondrial carnitine palmitoyltransferase. Effect of pH and malonyl-CoA.
    The Journal of biological chemistry, 1984, Nov-10, Volume: 259, Issue:21

    Topics: Acyl Coenzyme A; Acyltransferases; Animals; Carnitine; Carnitine O-Palmitoyltransferase; Cattle; Hydrogen-Ion Concentration; Kinetics; Malonyl Coenzyme A; Mitochondria, Heart; Palmitoyl Coenzyme A; Protein Binding

1984
Observations on the affinity for carnitine, and malonyl-CoA sensitivity, of carnitine palmitoyltransferase I in animal and human tissues. Demonstration of the presence of malonyl-CoA in non-hepatic tissues of the rat.
    The Biochemical journal, 1983, Jul-15, Volume: 214, Issue:1

    Topics: Acyl Coenzyme A; Acyltransferases; Animals; Carnitine; Carnitine O-Palmitoyltransferase; Dogs; Female; Guinea Pigs; Humans; In Vitro Techniques; Kinetics; Liver; Male; Malonyl Coenzyme A; Mitochondria; Muscles; Myocardium; Palmitoyl Coenzyme A; Rats; Rats, Inbred Strains; Starvation

1983
Time-dependence of inhibition of carnitine palmitoyltransferase I by malonyl-CoA in mitochondria isolated from livers of fed or starved rats. Evidence for transition of the enzyme between states of low and high affinity for malonyl-CoA.
    The Biochemical journal, 1984, Mar-01, Volume: 218, Issue:2

    Topics: Acyl Coenzyme A; Acyltransferases; Animals; Carnitine; Carnitine O-Palmitoyltransferase; Female; In Vitro Techniques; Isoenzymes; Malonyl Coenzyme A; Mitochondria, Liver; Rats; Starvation; Time Factors

1984
Regulation of hepatic fatty acid metabolism. The activities of mitochondrial and microsomal acyl-CoA:sn-glycerol 3-phosphate O-acyltransferase and the concentrations of malonyl-CoA, non-esterified and esterified carnitine, glycerol 3-phosphate, ketone bod
    The Biochemical journal, 1981, Jul-15, Volume: 198, Issue:1

    Topics: Acyl Coenzyme A; Animals; Carnitine; Fatty Acids; Female; Glycerol-3-Phosphate O-Acyltransferase; Glycerophosphates; Ketone Bodies; Lactation; Liver; Malonyl Coenzyme A; Pregnancy; Rats; Starvation; Weaning

1981
Cold acclimation increases carnitine palmitoyltransferase I activity in oxidative muscle of striped bass.
    The American journal of physiology, 1994, Volume: 266, Issue:2 Pt 2

    Topics: Acclimatization; Analysis of Variance; Animals; Bass; Carnitine; Carnitine O-Palmitoyltransferase; Cold Temperature; Kinetics; Malonyl Coenzyme A; Mitochondria, Muscle; Muscles; Oxygen Consumption

1994
Propionyl L-carnitine improvement of hypertrophied rat heart function is associated with an increase in cardiac efficiency.
    European journal of pharmacology, 1995, Nov-14, Volume: 286, Issue:2

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Adenosine Triphosphate; Animals; Cardiomegaly; Cardiotonic Agents; Carnitine; Heart; In Vitro Techniques; Male; Malonyl Coenzyme A; Myocardium; Rats; Rats, Inbred WKY

1995
Effect of pH and acyl-CoA chain length on the conversion of heart mitochondrial CPT-I/CPTo to a high affinity, malonyl-CoA-inhibited state.
    Biochimica et biophysica acta, 1996, Aug-13, Volume: 1290, Issue:3

    Topics: Acyl Coenzyme A; Animals; Carnitine; Carnitine O-Palmitoyltransferase; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Hydrogen-Ion Concentration; Malonyl Coenzyme A; Mitochondria, Heart; Palmitoyl Coenzyme A; Rats

1996
Functional studies of yeast-expressed human heart muscle carnitine palmitoyltransferase I.
    Archives of biochemistry and biophysics, 1997, Nov-01, Volume: 347, Issue:1

    Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Carnitine; Carnitine O-Palmitoyltransferase; Cloning, Molecular; Gene Expression; Humans; Immunoblotting; Kinetics; Malonyl Coenzyme A; Mitochondria; Molecular Sequence Data; Myocardium; Palmitoyl Coenzyme A; Pichia; Rats; Recombinant Proteins; RNA, Messenger

1997
Regulation of carbohydrate and fatty acid utilization by L-carnitine during cardiac development and hypoxia.
    Molecular and cellular biochemistry, 1998, Volume: 180, Issue:1-2

    Topics: Animals; Animals, Newborn; Caprylates; Carbohydrate Metabolism; Carnitine; Cell Hypoxia; Fatty Acids; Glycolysis; Heart; Malonyl Coenzyme A; Myocardium; Oxidation-Reduction; Swine

1998
Expression and possible role of muscle-type carnitine palmitoyltransferase I during sperm development in the rat.
    Biology of reproduction, 1998, Volume: 59, Issue:6

    Topics: Animals; Blotting, Northern; Carnitine; Carnitine O-Palmitoyltransferase; Enzyme Inhibitors; Epoxy Compounds; Gene Expression; In Situ Hybridization; Isoenzymes; Male; Malonyl Coenzyme A; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; RNA, Messenger; Spermatogenesis; Spermatozoa; Testis

1998
Comparisons of flux control exerted by mitochondrial outer-membrane carnitine palmitoyltransferase over ketogenesis in hepatocytes and mitochondria isolated from suckling or adult rats.
    European journal of biochemistry, 1999, Volume: 259, Issue:3

    Topics: Animals; Animals, Suckling; Carbon Dioxide; Carnitine; Carnitine O-Palmitoyltransferase; Cells, Cultured; Energy Metabolism; Enzyme Inhibitors; Epoxy Compounds; Ketone Bodies; Liver; Malonyl Coenzyme A; Membrane Proteins; Mitochondria, Liver; Palmitic Acid; Palmitoyl Coenzyme A; Palmitoylcarnitine; Rats; Rats, Wistar

1999
Kinetic investigation of carnitine palmitoyltransferases in homogenates of human skeletal muscle using L-amino-carnitine and malonyl-CoA.
    Advances in experimental medicine and biology, 1999, Volume: 466

    Topics: Betaine; Carnitine; Carnitine O-Palmitoyltransferase; Enzyme Inhibitors; Humans; Isoenzymes; Kinetics; Malonyl Coenzyme A; Mitochondria, Muscle; Muscle, Skeletal

1999
Use of six chimeric proteins to investigate the role of intramolecular interactions in determining the kinetics of carnitine palmitoyltransferase I isoforms.
    The Journal of biological chemistry, 2000, Jun-30, Volume: 275, Issue:26

    Topics: Amino Acid Sequence; Animals; Carnitine; Carnitine O-Palmitoyltransferase; Cell Membrane; DNA, Complementary; Dose-Response Relationship, Drug; Inhibitory Concentration 50; Kinetics; Malonyl Coenzyme A; Molecular Sequence Data; Palmitoyl Coenzyme A; Pichia; Plasmids; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; Rats; Recombinant Fusion Proteins; Sequence Homology, Amino Acid

2000
Malonyl-CoA content and fatty acid oxidation in rat muscle and liver in vivo.
    American journal of physiology. Endocrinology and metabolism, 2000, Volume: 279, Issue:2

    Topics: Acetyl-CoA Carboxylase; Allosteric Regulation; Animals; Blood Glucose; Body Weight; Carboxy-Lyases; Carnitine; Citric Acid; Eating; Fatty Acids; Fatty Acids, Nonesterified; Food Deprivation; Glycogen; Insulin; Liver; Male; Malonyl Coenzyme A; Muscle, Skeletal; Oxidation-Reduction; Pulmonary Gas Exchange; Rats; Rats, Sprague-Dawley

2000
Identification of positive and negative determinants of malonyl-CoA sensitivity and carnitine affinity within the amino termini of rat liver- and muscle-type carnitine palmitoyltransferase I.
    The Journal of biological chemistry, 2000, Dec-08, Volume: 275, Issue:49

    Topics: Animals; Carnitine; Carnitine O-Palmitoyltransferase; Cloning, Molecular; Kinetics; Liver; Malonyl Coenzyme A; Muscle, Skeletal; Mutagenesis, Site-Directed; Peptide Fragments; Pichia; Rats; Recombinant Proteins; Sequence Deletion

2000
Distinct kinetics of carnitine palmitoyltransferase i in contact sites and outer membranes of rat liver mitochondria.
    The Journal of biological chemistry, 2001, Jun-08, Volume: 276, Issue:23

    Topics: Animals; Carnitine; Carnitine O-Palmitoyltransferase; Catalysis; Intracellular Membranes; Kinetics; Male; Malonyl Coenzyme A; Mitochondria, Liver; Palmitoyl Coenzyme A; Rats; Rats, Wistar

2001
Pig liver carnitine palmitoyltransferase I, with low Km for carnitine and high sensitivity to malonyl-CoA inhibition, is a natural chimera of rat liver and muscle enzymes.
    Biochemistry, 2001, Feb-20, Volume: 40, Issue:7

    Topics: Amino Acid Sequence; Animals; Base Sequence; Carnitine; Carnitine O-Palmitoyltransferase; Cloning, Molecular; DNA, Complementary; Enzyme Inhibitors; Humans; Isoenzymes; Kinetics; Malonyl Coenzyme A; Mice; Mitochondria, Liver; Mitochondria, Muscle; Molecular Sequence Data; Organ Specificity; Pichia; Rats; Sequence Alignment; Swine

2001
Acute regulation of fatty acid oxidation and amp-activated protein kinase in human umbilical vein endothelial cells.
    Circulation research, 2001, Jun-22, Volume: 88, Issue:12

    Topics: 3-O-Methylglucose; Acetyl-CoA Carboxylase; Adenosine Triphosphate; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Caprylates; Carnitine; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Energy Metabolism; Enzyme Activation; Fatty Acids; Glucose; Glycolysis; Humans; Intracellular Fluid; Malonyl Coenzyme A; Multienzyme Complexes; Oxidation-Reduction; Palmitic Acid; Protein Serine-Threonine Kinases; Ribonucleotides; Tritium; Umbilical Veins

2001
Specificity of the interactions between Glu-3, Ser-24, and Gln-30 within the N-terminal segment of rat liver mitochondrial overt carnitine palmitoyltransferase (L-CPT I) in determining the malonyl-CoA sensitivity of the enzyme.
    Biochemistry, 2001, Dec-04, Volume: 40, Issue:48

    Topics: Animals; Carnitine; Carnitine O-Palmitoyltransferase; DNA Primers; Glutamic Acid; Glutamine; Malonyl Coenzyme A; Mitochondria, Liver; Palmitoyl Coenzyme A; Peptide Fragments; Pichia; Plasmids; Point Mutation; Protein Structure, Secondary; Rats; Recombinant Proteins; Serine

2001
Substrate utilization during graded aerobic exercise in rainbow trout.
    The Journal of experimental biology, 2002, Volume: 205, Issue:Pt 14

    Topics: Acetylation; Adenosine Triphosphate; Aerobiosis; Animals; Carbohydrate Metabolism; Carnitine; Glucose; Glycogen; Glycolysis; Kinetics; Lactic Acid; Lipid Metabolism; Malonyl Coenzyme A; Muscle, Skeletal; Oncorhynchus mykiss; Oxidation-Reduction; Oxygen Consumption; Phosphocreatine; Physical Exertion; Pyruvate Dehydrogenase Complex; Swimming; Triglycerides

2002
Relative importance of malonyl CoA and carnitine in maturation of fatty acid oxidation in newborn rabbit heart.
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 284, Issue:1

    Topics: Animals; Animals, Newborn; Carnitine; Carnitine O-Palmitoyltransferase; Fatty Acids; Glucose; In Vitro Techniques; Isoenzymes; Kinetics; Malonyl Coenzyme A; Mitochondria, Heart; Myocardium; Rabbits; RNA, Messenger

2003
A single amino acid change (substitution of the conserved Glu-590 with alanine) in the C-terminal domain of rat liver carnitine palmitoyltransferase I increases its malonyl-CoA sensitivity close to that observed with the muscle isoform of the enzyme.
    The Journal of biological chemistry, 2003, Sep-05, Volume: 278, Issue:36

    Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Blotting, Western; Carnitine; Carnitine O-Palmitoyltransferase; Chickens; Dose-Response Relationship, Drug; Glutamic Acid; Glutamine; Humans; Immunoblotting; Kinetics; Liver; Lysine; Malonyl Coenzyme A; Mice; Molecular Sequence Data; Muscles; Mutation; Palmitoyl Coenzyme A; Pichia; Polymerase Chain Reaction; Protein Isoforms; Protein Structure, Tertiary; Rats; Sequence Homology, Amino Acid; Swine

2003
Different sensitivities of CPT I and CPT II for inhibition by l-aminocarnitine in human skeletal muscle.
    Biochimica et biophysica acta, 2004, Feb-15, Volume: 1608, Issue:2-3

    Topics: Betaine; Biopsy; Carnitine; Carnitine O-Palmitoyltransferase; Enzyme Inhibitors; Humans; Malonyl Coenzyme A; Mitochondria, Muscle; Muscle Fibers, Skeletal; Muscle, Skeletal; Oxygen Consumption; Rhabdomyolysis

2004
Malonyl-CoA and carnitine in regulation of fat oxidation in human skeletal muscle during exercise.
    American journal of physiology. Endocrinology and metabolism, 2005, Volume: 288, Issue:1

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Acetylcarnitine; Adenylate Kinase; Adult; Carnitine; Dietary Carbohydrates; Exercise; Fatty Acids; Glucose; Glycogen; Heart Rate; Humans; Insulin; Male; Malonyl Coenzyme A; Muscle, Skeletal; Oxidation-Reduction; Pyruvate Dehydrogenase Complex

2005
Pig muscle carnitine palmitoyltransferase I (CPTI beta), with low Km for carnitine and low sensitivity to malonyl-CoA inhibition, has kinetic characteristics similar to those of the rat liver (CPTI alpha) enzyme.
    Biochemistry, 2004, Oct-05, Volume: 43, Issue:39

    Topics: Amino Acid Sequence; Animals; Carnitine; Carnitine O-Palmitoyltransferase; Cloning, Molecular; Enzyme Inhibitors; Humans; Isoenzymes; Kinetics; Malonyl Coenzyme A; Mice; Mitochondria, Liver; Mitochondria, Muscle; Molecular Sequence Data; Rats; Recombinant Proteins; Sequence Homology, Amino Acid; Swine

2004
Differential carnitine/acylcarnitine translocase expression defines distinct metabolic signatures in skeletal muscle cells.
    Journal of cellular physiology, 2005, Volume: 203, Issue:2

    Topics: Acetyl-CoA Carboxylase; Acetylcarnitine; Acyl Coenzyme A; Antisense Elements (Genetics); Carnitine; Carnitine Acyltransferases; Carnitine O-Palmitoyltransferase; Cell Line; Down-Regulation; Energy Metabolism; Gene Expression Regulation, Enzymologic; Humans; Insulin; Lipid Metabolism; Malonyl Coenzyme A; Mitochondria; Muscle Fibers, Skeletal; Muscle, Skeletal; Palmitates; RNA, Antisense

2005
Cysteine-scanning mutagenesis of muscle carnitine palmitoyltransferase I reveals a single cysteine residue (Cys-305) is important for catalysis.
    The Journal of biological chemistry, 2005, Feb-11, Volume: 280, Issue:6

    Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Blotting, Western; Carnitine; Carnitine O-Palmitoyltransferase; Catalysis; Cysteine; DNA Primers; Humans; Kinetics; Malonyl Coenzyme A; Models, Chemical; Molecular Sequence Data; Mutagenesis; Mutation; Myocardium; Palmitic Acid; Palmitoylcarnitine; Pichia; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine

2005
The brain-specific carnitine palmitoyltransferase-1c regulates energy homeostasis.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, May-09, Volume: 103, Issue:19

    Topics: Animals; Body Weight; Brain; Carnitine; Carnitine Acyltransferases; Carnitine O-Palmitoyltransferase; Catalysis; Fats; Fatty Acids; Feeding Behavior; Homeostasis; Malonyl Coenzyme A; Mice; Mice, Knockout; Oxidation-Reduction; Protein Binding

2006
Definition by functional and structural analysis of two malonyl-CoA sites in carnitine palmitoyltransferase 1A.
    The Journal of biological chemistry, 2007, Jun-22, Volume: 282, Issue:25

    Topics: Amino Acid Sequence; Binding Sites; Carnitine; Carnitine O-Palmitoyltransferase; Humans; Inhibitory Concentration 50; Kinetics; Malonyl Coenzyme A; Molecular Conformation; Molecular Sequence Data; Mutation; Protein Binding; Protein Structure, Tertiary; Saccharomyces cerevisiae; Sequence Homology, Amino Acid

2007
Long chain fatty acyl-CoA modulation of H(2)O (2) release at mitochondrial complex I.
    Journal of bioenergetics and biomembranes, 2008, Volume: 40, Issue:1

    Topics: Animals; Carnitine; Electron Transport; Electron Transport Complex I; Hydrogen Peroxide; Malonyl Coenzyme A; Mitochondria, Heart; NADP; Oxidation-Reduction; Rats; Succinic Acid

2008
Rat liver mitochondrial carnitine palmitoyltransferase-I, hepatic carnitine, and malonyl-CoA: effect of starvation.
    Archives of physiology and biochemistry, 2008, Volume: 114, Issue:3

    Topics: Animals; Blotting, Western; Body Weight; Carnitine; Carnitine O-Palmitoyltransferase; Electrophoresis, Polyacrylamide Gel; Liver; Male; Malonyl Coenzyme A; Mitochondria, Liver; Organ Size; Rats; Rats, Sprague-Dawley; Starvation

2008
A characteristic Glu17 residue of pig carnitine palmitoyltransferase 1 is responsible for the low Km for carnitine and the low sensitivity to malonyl-CoA inhibition of the enzyme.
    The FEBS journal, 2009, Volume: 276, Issue:1

    Topics: Amino Acid Substitution; Animals; Carnitine; Carnitine O-Palmitoyltransferase; Enzyme Inhibitors; Glutamic Acid; Humans; Kinetics; Malonyl Coenzyme A; Microsomes; Mitochondria; Neurons; Sequence Deletion; Swine

2009
Comparative study of sesame lignans (sesamin, episesamin and sesamolin) affecting gene expression profile and fatty acid oxidation in rat liver.
    Journal of nutritional science and vitaminology, 2009, Volume: 55, Issue:1

    Topics: Adipose Tissue; Animals; Antioxidants; Blood Glucose; Carbohydrate Metabolism; Carnitine; Coenzyme A; Epididymis; Gene Expression; Lignans; Lipid Metabolism; Liver; Male; Malonyl Coenzyme A; Mitochondria; Organ Size; Oxidation-Reduction; Peroxisomes; Rats; Rats, Sprague-Dawley; RNA, Messenger; Seeds; Sesamum

2009
Fatty acid oxidation and meiotic resumption in mouse oocytes.
    Molecular reproduction and development, 2009, Volume: 76, Issue:9

    Topics: 4-Butyrolactone; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Carnitine; Carnitine O-Palmitoyltransferase; Cerulenin; Cumulus Cells; Epoxy Compounds; Fatty Acids; Female; Malonyl Coenzyme A; Meiosis; Mice; Mice, Inbred C57BL; Oocytes; Oxidation-Reduction; Palmitic Acid; Ribonucleotides

2009
Atypical antipsychotics rapidly and inappropriately switch peripheral fuel utilization to lipids, impairing metabolic flexibility in rodents.
    Schizophrenia bulletin, 2012, Volume: 38, Issue:1

    Topics: Animals; Antipsychotic Agents; Benzodiazepines; Carnitine; Clozapine; Energy Metabolism; Fatty Acids, Nonesterified; Female; Haloperidol; Insulin Resistance; Lipolysis; Male; Malonyl Coenzyme A; Mice; Olanzapine; Piperazines; Rats; Rats, Sprague-Dawley; Risperidone; Thiazoles; Vitamin B Complex

2012
Metabolic profiling of muscle contraction in lean compared with obese rodents.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2010, Volume: 299, Issue:3

    Topics: Acetyl-CoA Carboxylase; Animals; Biological Transport; Carnitine; Glucose; Glycogen; Lactic Acid; Lipids; Malonyl Coenzyme A; Muscle Contraction; Muscle, Skeletal; Obesity; Pyruvic Acid; Rats; Rats, Zucker; Sciatic Nerve; Triglycerides

2010
Use of a long-chain triglyceride-restricted/medium-chain triglyceride-supplemented diet in a case of malonyl-CoA decarboxylase deficiency with cardiomyopathy.
    Journal of inherited metabolic disease, 2010, Volume: 33 Suppl 3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Carboxy-Lyases; Cardiomyopathies; Carnitine; Child, Preschool; Combined Modality Therapy; Dietary Supplements; Female; Genetic Predisposition to Disease; Humans; Infant; Infant Formula; Infant Nutritional Physiological Phenomena; Infant, Newborn; Malonyl Coenzyme A; Metabolism, Inborn Errors; Methylmalonic Acid; Mutation; Nutritional Status; Phenotype; Treatment Outcome; Triglycerides

2010
Malonylcarnitine in newborns with non-syndromic cleft lip with or without cleft palate.
    International journal of oral science, 2010, Volume: 2, Issue:3

    Topics: Acetylcarnitine; Carnitine; Chromatography, Liquid; Cleft Lip; Cleft Palate; Female; Humans; Infant, Newborn; Likelihood Functions; Male; Malonates; Malonyl Coenzyme A; Neonatal Screening; Retrospective Studies; Tandem Mass Spectrometry

2010
Cardiac-specific deletion of acetyl CoA carboxylase 2 prevents metabolic remodeling during pressure-overload hypertrophy.
    Circulation research, 2012, Aug-31, Volume: 111, Issue:6

    Topics: Acetyl-CoA Carboxylase; Animals; Aorta; Blotting, Western; Cardiomegaly; Carnitine; Constriction, Pathologic; Fatty Acids; Female; Fibrosis; Heart; In Vitro Techniques; Male; Malonyl Coenzyme A; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Mitochondria, Heart; Myocardium; Oxidation-Reduction; Pressure; Ventricular Remodeling

2012
Malonyl coenzyme A decarboxylase deficiency: early dietary restriction and time course of cardiomyopathy.
    Pediatrics, 2012, Volume: 130, Issue:2

    Topics: Alleles; Carboxy-Lyases; Cardiomyopathies; Carnitine; Chromosome Aberrations; Chromosome Deletion; Codon, Terminator; Dietary Fats; DNA Mutational Analysis; Echocardiography, Doppler, Color; Female; Frameshift Mutation; Genes, Recessive; Homozygote; Humans; Infant; Infant Formula; Infant, Newborn; Isolated Noncompaction of the Ventricular Myocardium; Malonyl Coenzyme A; Metabolism, Inborn Errors; Methylmalonic Acid; Neonatal Screening; Phenotype; Rare Diseases; Triglycerides

2012
Identification of a novel malonyl-CoA IC(50) for CPT-I: implications for predicting in vivo fatty acid oxidation rates.
    The Biochemical journal, 2012, Nov-15, Volume: 448, Issue:1

    Topics: Animals; Carnitine; Carnitine O-Palmitoyltransferase; Cell Membrane Permeability; Dose-Response Relationship, Drug; Fatty Acids; Inhibitory Concentration 50; Kinetics; Malonyl Coenzyme A; Mitochondria, Muscle; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; Oxidation-Reduction; Oxygen Consumption; Palmitoyl Coenzyme A; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley

2012
Differential effects of central ghrelin on fatty acid metabolism in hypothalamic ventral medial and arcuate nuclei.
    Physiology & behavior, 2013, Jun-13, Volume: 118

    Topics: Acyl Coenzyme A; AMP-Activated Protein Kinases; Animals; Arcuate Nucleus of Hypothalamus; Blotting, Western; Carboxy-Lyases; Carnitine; Carnitine O-Palmitoyltransferase; Fatty Acids; Ghrelin; Injections, Intraventricular; Lipid Metabolism; Male; Malonyl Coenzyme A; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; RNA, Messenger; Ventromedial Hypothalamic Nucleus

2013
Important role of ventromedial hypothalamic carnitine palmitoyltransferase-1a in the control of food intake.
    American journal of physiology. Endocrinology and metabolism, 2013, Aug-01, Volume: 305, Issue:3

    Topics: Acyl Coenzyme A; Animals; Appetite Depressants; Arcuate Nucleus of Hypothalamus; Blotting, Western; Body Weight; Carnitine; Carnitine O-Palmitoyltransferase; Dependovirus; Eating; Enzyme Activation; Epoxy Compounds; Fasting; Genetic Vectors; Hypoglycemic Agents; Injections, Intraventricular; Male; Malonyl Coenzyme A; Rats; Rats, Sprague-Dawley; Ventromedial Hypothalamic Nucleus

2013
Inhibition of gene expression of carnitine palmitoyltransferase I and heart fatty acid binding protein in cyclophosphamide and ifosfamide-induced acute cardiotoxic rat models.
    Cardiovascular toxicology, 2014, Volume: 14, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Blotting, Western; Cardiomyopathies; Cardiotoxicity; Carnitine; Carnitine O-Palmitoyltransferase; Creatine Kinase, MB Form; Cyclophosphamide; Disease Models, Animal; Fatty Acid-Binding Proteins; Gene Expression Regulation; Ifosfamide; L-Lactate Dehydrogenase; Male; Malonyl Coenzyme A; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; RNA, Messenger

2014
Biochemical, molecular and outcome analysis of eight chinese asymptomatic individuals with methyl malonic acidemia detected through newborn screening.
    American journal of medical genetics. Part A, 2015, Volume: 167A, Issue:10

    Topics: Acetylcarnitine; Acidosis; Asian People; Asymptomatic Diseases; Carboxy-Lyases; Carnitine; Carrier Proteins; Child; Citrates; Female; Gene Expression; Humans; Infant; Infant, Newborn; Male; Malonates; Malonyl Coenzyme A; Metabolism, Inborn Errors; Methylmalonic Acid; Methylmalonyl-CoA Mutase; Mutation; Neonatal Screening; Oxidoreductases

2015
The Carnitine Palmitoyl Transferase (CPT) System and Possible Relevance for Neuropsychiatric and Neurological Conditions.
    Molecular neurobiology, 2015, Volume: 52, Issue:2

    Topics: Animals; Brain; Cardiovascular Diseases; Carnitine; Carnitine O-Palmitoyltransferase; Ceramides; Diabetes Mellitus, Type 2; Disease Progression; Eating; Endocannabinoids; Energy Metabolism; Fatty Acids; Humans; Hypoglycemia; Insulin; Learning; Lipid Metabolism, Inborn Errors; Malonyl Coenzyme A; Metabolic Syndrome; Mitochondria; Mitochondria, Liver; Mitochondria, Muscle; Multienzyme Complexes; Neurodegenerative Diseases; Oxidation-Reduction; Protein Isoforms

2015
Carnitine Supplementation Attenuates Sunitinib-Induced Inhibition of AMP-Activated Protein Kinase Downstream Signals in Cardiac Tissues.
    Cardiovascular toxicology, 2019, Volume: 19, Issue:4

    Topics: Acetyl-CoA Carboxylase; Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Cardiotoxicity; Carnitine; Carnitine O-Palmitoyltransferase; Dietary Supplements; Energy Metabolism; Heart Diseases; Male; Malonyl Coenzyme A; Mitochondria, Heart; Myocytes, Cardiac; Protein Kinase Inhibitors; Rats, Wistar; Signal Transduction; Sunitinib

2019
Heterogenous Clinical Landscape in a Consanguineous Malonic Aciduria Family.
    International journal of molecular sciences, 2021, Nov-23, Volume: 22, Issue:23

    Topics: Carboxy-Lyases; Carnitine; Child, Preschool; Consanguinity; Homozygote; Humans; Male; Malonates; Malonyl Coenzyme A; Metabolism, Inborn Errors; Methylmalonic Acid; Pedigree; Point Mutation

2021