carnitine has been researched along with cardiovascular agents in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (15.63) | 18.2507 |
| 2000's | 13 (40.63) | 29.6817 |
| 2010's | 13 (40.63) | 24.3611 |
| 2020's | 1 (3.13) | 2.80 |
| Authors | Studies |
|---|---|
| Bertelli, A; Bertelli, AA; Galmozzi, G; Giovannini, L | 1 |
| Bartels, GL; Holwerda, KJ; Kruijssen, DA; Remme, WJ | 1 |
| Arsenian, MA; Cafasso, CM; New, PS | 1 |
| Asaka, N; Kirimoto, T; Miyake, H; Muranaka, Y | 1 |
| Harashima, H; Hayashi, M; Ise, S; Kiwada, H; Kuwajima, M; Lu, Km; Sei, M; Shima, K; Sugiyama, Y | 1 |
| Aoyagi, T; Eto, Y; Hayashi, Y; Kirimoto, T; Matsumoto, A; Momomura, S; Omata, M; Sugiura, S; Yokoyama, I; Yonekura, K | 1 |
| Dambrova, M; Kalvinsh, I; Liepinsh, E | 1 |
| Hill, JA; Schofield, RS | 1 |
| André, A; Clouet, P; Degrace, P; Demaison, L; Demizieux, L; Gresti, J; Tsoko, M | 1 |
| Daĭia, D; Dambrova, M; Kalvin'sh, I; Kir'ianova, O; Liepin'sh, E | 1 |
| Pauly, DF; Pepine, CJ | 1 |
| Arduini, A; Carminati, P; Giannessi, F; Giarrizzo, MG; Peschechera, A; Ricciolini, R; Russo, F; Scalibastri, M | 1 |
| Sakvarelidze, EP | 1 |
| Dambrova, M; Kalvinsh, I; Kirjanova, O; Liepinsh, E; Loca, D; Pugovichs, O; Vilskersts, R | 1 |
| Izzo, A; Koverech, A; Liguori, M; Messano, M; Palermo, G; Riccioni, C; Sarcinella, R; Virmani, A | 1 |
| Chlopicki, S; Dambrova, M; Grinberga, S; Kalvinsh, I; Liepinsh, E; Mateuszuk, L; Vilskersts, R | 1 |
| Cirule, H; Dambrova, M; Grinberga, S; Kalvinsh, I; Kuka, J; Liepinsh, E; Skapare, E; Svalbe, B; Vilskersts, R; Zvejniece, L | 1 |
| Cirule, H; Dambrova, M; Kalvinsh, I; Kuka, J; Liepinsh, E; Pugovics, O; Skapare, E; Svalbe, B; Vilskersts, R | 1 |
| Alvarez de Sotomayor, M; Herrera, MD; Justo, ML; Mingorance, C; Rodríguez-Rodríguez, R | 1 |
| Dambrova, M; Grinberga, S; Kalvinsh, I; Konrade, I; Kuka, J; Liepinsh, E; Pugovics, O; Skapare, E | 1 |
| Cirule, H; Dambrova, M; Grinberga, S; Kalvinsh, I; Kuka, J; Liepinsh, E; Svalbe, B; Vilskersts, R | 1 |
| Cirule, H; Dambrova, M; Kalvinsh, I; Kuka, J; Liepinsh, E; Makrecka, M; Pugovics, O; Vilskersts, R | 1 |
| Cirule, H; Dambrova, M; Grinberga, S; Mezhapuke, R; Vilskersts, R; Zharkova-Malkova, O | 1 |
| Dambrova, M; Grinberga, S; Kalvins, I; Konrade, I; Liepins, E; Petrovska, R; Pugovics, O; Skapare-Makarova, E; Tirzite, D | 1 |
| Dinicolantonio, JJ; Lavie, CJ; Liberopoulos, E; McCarty, MF; Niazi, AK; O'Keefe, JH | 1 |
| Li, H; Shang, R; Sun, Z | 1 |
| Arduini, A; Zammit, VA | 1 |
| Jargin, SV | 1 |
| Heggermont, WA; Heymans, S; Papageorgiou, AP; van Bilsen, M | 1 |
| Bi, Y; Cates, C; Chen, X; Guo, Z; Hu, H; Li, J; Liu, X; Rousselle, T; Xue, M; Yin, J; Zhu, P; Zhuang, J | 1 |
| Berge, RK; Bjørndal, B; Hallström, S; Lindquist, C; Rossmann, CR; Svardal, A | 1 |
| Gryaznova, MV; Gureev, AP; Ignatyeva, DA; Popov, VN; Shaforostova, EA; Volodina, DE | 1 |
8 review(s) available for carnitine and cardiovascular agents
| Article | Year |
|---|---|
Mildronate: cardioprotective action through carnitine-lowering effect.
Topics: Cardiotonic Agents; Cardiovascular Agents; Carnitine; Energy Metabolism; Humans; Methylhydrazines | 2002 |
Role of metabolically active drugs in the management of ischemic heart disease.
Topics: Acetanilides; Animals; Cardiovascular Agents; Carnitine; Clinical Trials as Topic; Dichloroacetic Acid; Energy Metabolism; Fatty Acids; Glucose; Humans; Insulin; Myocardial Ischemia; Myocardium; Piperazines; Potassium; Ranolazine; Trimetazidine | 2001 |
[Biochemical mechanisms of mildronate action during ischemic stress].
Topics: Animals; Cardiovascular Agents; Carnitine; Clinical Trials as Topic; Humans; Methylhydrazines; Myocardial Ischemia; Myocardium; Oxidative Stress; Treatment Outcome | 2004 |
Ischemic heart disease: metabolic approaches to management.
Topics: Acetanilides; Cardiovascular Agents; Carnitine; Dichloroacetic Acid; Energy Metabolism; Humans; Myocardial Ischemia; Oxidation-Reduction; Piperazines; Ranolazine; Ribose; Trimetazidine | 2004 |
Critical update for the clinical use of L-carnitine analogs in cardiometabolic disorders.
Topics: Acetylcarnitine; Animals; Cardiovascular Agents; Cardiovascular Diseases; Carnitine; Diabetes Mellitus, Type 2; Evidence-Based Medicine; Humans; Hypoglycemic Agents; Insulin Resistance; Treatment Outcome | 2011 |
L-carnitine for the treatment of acute myocardial infarction.
Topics: Acyl Coenzyme A; Animals; Cardiovascular Agents; Carnitine; Energy Metabolism; Glucose; Humans; Myocardial Infarction; Myocardium; Oxidation-Reduction; Treatment Outcome | 2014 |
Effective dosing of L-carnitine in the secondary prevention of cardiovascular disease: a systematic review and meta-analysis.
Topics: Administration, Oral; Cardiovascular Agents; Cardiovascular Diseases; Carnitine; Chi-Square Distribution; Drug Administration Schedule; Drug Dosage Calculations; Humans; Odds Ratio; Recurrence; Risk Factors; Secondary Prevention; Treatment Outcome | 2014 |
Metabolic support for the heart: complementary therapy for heart failure?
Topics: Acetyl-CoA C-Acyltransferase; Cardiovascular Agents; Carnitine; Carnitine O-Palmitoyltransferase; Dichloroacetic Acid; Energy Metabolism; Enzyme Inhibitors; Epoxy Compounds; Fatty Acids; Glucose; Heart Failure; Humans; Myocardium; Myocytes, Cardiac; Oxidation-Reduction; Perhexiline; Ranolazine; Stroke Volume; Trimetazidine | 2016 |
4 trial(s) available for carnitine and cardiovascular agents
| Article | Year |
|---|---|
Anti-ischaemic efficacy of L-propionylcarnitine--a promising novel metabolic approach to ischaemia?
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Cardiotonic Agents; Cardiovascular Agents; Carnitine; Cross-Over Studies; Diltiazem; Double-Blind Method; Electrocardiography, Ambulatory; Exercise Test; Female; Heart Rate; Humans; Male; Middle Aged; Treatment Outcome | 1996 |
Evaluation of the efficacy of propionyl-L-carnitine versus pulsed muscular compressions in diabetic and non-diabetic patients affected by obliterating arteriopathy Leriche stage II.
Topics: Aged; Arterial Occlusive Diseases; Cardiovascular Agents; Carnitine; Combined Modality Therapy; Diabetes Mellitus, Type 2; Female; Humans; Infusions, Intravenous; Intermittent Claudication; Intermittent Pneumatic Compression Devices; Male; Middle Aged; Quality of Life; Recovery of Function; Severity of Illness Index; Time Factors; Treatment Outcome; Walking | 2008 |
Mildronate treatment alters γ-butyrobetaine and l-carnitine concentrations in healthy volunteers.
Topics: Adult; Betaine; Cardiovascular Agents; Carnitine; Diet; Female; Humans; Male; Meat; Methylhydrazines; Middle Aged; Young Adult | 2011 |
Meldonium decreases the diet-increased plasma levels of trimethylamine N-oxide, a metabolite associated with atherosclerosis.
Topics: Adult; Atherosclerosis; Cardiovascular Agents; Carnitine; Diet; Female; HEK293 Cells; Humans; Male; Methylamines; Methylhydrazines; Organic Cation Transport Proteins; Seafood; Solute Carrier Family 22 Member 5 | 2013 |
20 other study(ies) available for carnitine and cardiovascular agents
| Article | Year |
|---|---|
Protective role of propionyl carnitine in vascular disorders experimentally induced by endothelin (ET-1) serotonin and K-carrageenin.
Topics: Animals; Cardiovascular Agents; Carnitine; Carrageenan; Endothelins; Male; Rats; Rats, Wistar; Regional Blood Flow; Serotonin; Tail; Thrombosis; Vascular Diseases | 1993 |
Safety, tolerability, and efficacy of a glucose-insulin-potassium-magnesium-carnitine solution in acute myocardial infarction.
Topics: Aged; Blood Glucose; Calcium; Cardiovascular Agents; Carnitine; Diuretics; Drug Tolerance; Female; Furosemide; Glucose; Humans; Hypertonic Solutions; Hypoglycemic Agents; Infusions, Intravenous; Insulin; Magnesium; Male; Myocardial Infarction; Phosphorus; Potassium; Safety; Thrombolytic Therapy | 1996 |
Cardioprotective profile of MET-88, an inhibitor of carnitine synthesis, and insulin during hypoxia in isolated perfused rat hearts.
Topics: Administration, Oral; Animals; Cardiovascular Agents; Carnitine; Coronary Circulation; Glucose; Glycolysis; Heart; Hypoglycemic Agents; Hypoxia; In Vitro Techniques; Insulin; Lactic Acid; Male; Methylhydrazines; Myocardial Contraction; Oxidation-Reduction; Palmitates; Phosphates; Rats; Rats, Sprague-Dawley | 1998 |
Pharmacokinetic analysis of the cardioprotective effect of 3-(2,2, 2-trimethylhydrazinium) propionate in mice: inhibition of carnitine transport in kidney.
Topics: Animals; Cardiovascular Agents; Carnitine; Carnitine O-Palmitoyltransferase; Fibroblasts; In Vitro Techniques; Kidney; Male; Methylhydrazines; Mice; Mice, Inbred C57BL; Mitochondria, Heart; Myocardium; Rats; Rats, Sprague-Dawley | 1999 |
Inhibition of carnitine synthesis modulates protein contents of the cardiac sarcoplasmic reticulum Ca2+-ATPase and hexokinase type I in rat hearts with myocardial infarction.
Topics: Animals; Calcium-Transporting ATPases; Cardiovascular Agents; Carnitine; Hexokinase; Isoenzymes; Male; Methylhydrazines; Myocardial Infarction; Myocardium; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum Calcium-Transporting ATPases | 2000 |
Fatty acid oxidation and related gene expression in heart depleted of carnitine by mildronate treatment in the rat.
Topics: Animals; Biological Transport; Cardiovascular Agents; Carnitine; Carnitine O-Palmitoyltransferase; Esterification; Fatty Acids; Gene Expression Regulation; In Vitro Techniques; Lipoprotein Lipase; Male; Methylhydrazines; Mitochondria, Heart; Myocardium; Oxidation-Reduction; Oxygen Consumption; Palmitic Acid; Perfusion; Rats; Rats, Wistar; RNA, Messenger; Triglycerides | 2004 |
Carnitine depletion in rat pups from mothers given mildronate: a model of carnitine deficiency in late fetal and neonatal life.
Topics: Animals; Animals, Newborn; Cardiovascular Agents; Carnitine; Female; Heart; Lactation; Liver; Methylhydrazines; Milk; Muscles; Palmitates; Pregnancy; Rats; Rats, Sprague-Dawley; Tissue Distribution; Triglycerides | 2005 |
[Change of concentration of L-carnitine in blood and other tissues in rats on a background of the alcohol intake and influence of mildronate on its level].
Topics: Alcoholism; Animals; Cardiovascular Agents; Carnitine; Ethanol; Male; Methylhydrazines; Rats; Rats, Inbred Strains; Tissue Distribution | 2006 |
Mildronate, an inhibitor of carnitine biosynthesis, induces an increase in gamma-butyrobetaine contents and cardioprotection in isolated rat heart infarction.
Topics: Animals; Betaine; Cardiovascular Agents; Carnitine; Chromatography, High Pressure Liquid; Coronary Circulation; gamma-Butyrobetaine Dioxygenase; In Vitro Techniques; Injections, Intraperitoneal; Male; Methylhydrazines; Myocardial Infarction; Myocardium; Rats; Rats, Wistar | 2006 |
Mildronate, a regulator of energy metabolism, reduces atherosclerosis in apoE/LDLR-/- mice.
Topics: Animals; Aorta; Atherosclerosis; Betaine; Cardiovascular Agents; Carnitine; Energy Metabolism; Female; Lipids; Male; Methylhydrazines; Mice; Mice, Knockout; Rats; Rats, Wistar | 2009 |
Protective effects of mildronate in an experimental model of type 2 diabetes in Goto-Kakizaki rats.
Topics: 3-Hydroxybutyric Acid; Administration, Oral; Animals; Blood Glucose; Cardiovascular Agents; Carnitine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Fructosamine; Heart; Hyperalgesia; Hypoglycemic Agents; In Vitro Techniques; Lipids; Male; Methylhydrazines; Myocardial Ischemia; Pain Threshold; Rats; Rats, Wistar | 2009 |
Effects of long-term mildronate treatment on cardiac and liver functions in rats.
Topics: Animals; Betaine; Biomarkers; Blood Glucose; Body Weight; Cardiovascular Agents; Carnitine; Carnitine O-Palmitoyltransferase; Dose-Response Relationship, Drug; Glucose; Heart; Hemodynamics; Lipids; Liver; Liver Glycogen; Male; Methylhydrazines; Myocardium; Rats; Rats, Wistar; Time Factors; Toxicity Tests, Chronic | 2009 |
Administration of L-carnitine and mildronate improves endothelial function and decreases mortality in hypertensive Dahl rats.
Topics: Animals; Cardiovascular Agents; Carnitine; Endothelium, Vascular; Hypertension; Male; Methylhydrazines; Rats; Rats, Inbred Dahl; Sodium Chloride, Dietary; Survival Rate; Vitamin B Complex | 2011 |
The cardioprotective effect of mildronate is diminished after co-treatment with L-carnitine.
Topics: Animals; Betaine; Cardiovascular Agents; Carnitine; Carnitine O-Palmitoyltransferase; Chromatography, Liquid; Drug Interactions; Fatty Acids; Male; Methylhydrazines; Mitochondria, Heart; Mitochondrial Membranes; Myocardial Infarction; Myocardial Reperfusion Injury; Rats; Rats, Wistar; Tandem Mass Spectrometry; Vitamin B Complex | 2012 |
Elevated vascular γ-butyrobetaine levels attenuate the development of high glucose-induced endothelial dysfunction.
Topics: Animals; Aorta; Betaine; Cardiovascular Agents; Carnitine; Drug Therapy, Combination; Endothelium, Vascular; Glucose; Male; Methylhydrazines; Rats; Rats, Wistar | 2013 |
A tennis lesson: sharp practice in the science behind the Sharapova case.
Topics: Athletes; Cardiovascular Agents; Carnitine; Doping in Sports; Female; Heart; Humans; Methylhydrazines; Muscle, Skeletal; Performance-Enhancing Substances; Tennis | 2016 |
Meldonium (Mildronate): Primum nоn nocere.
Topics: Adjuvants, Immunologic; Animals; Cardiovascular Agents; Cardiovascular Diseases; Carnitine; Humans; Methylhydrazines; Randomized Controlled Trials as Topic | 2016 |
L-Carnitine Attenuates Cardiac Dysfunction by Ischemic Insults Through Akt Signaling Pathway.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cardiovascular Agents; Carnitine; Cell Hypoxia; Cells, Cultured; Cytoprotection; Disease Models, Animal; Mice, Inbred C57BL; Myocardial Contraction; Myocardial Reperfusion Injury; Myocytes, Cardiac; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; ST Elevation Myocardial Infarction; Time Factors; Ventricular Function, Left | 2017 |
A fatty acid analogue targeting mitochondria exerts a plasma triacylglycerol lowering effect in rats with impaired carnitine biosynthesis.
Topics: Animals; Cardiovascular Agents; Carnitine; Fatty Acids; Liver; Male; Methylhydrazines; Mitochondria; Oxidation-Reduction; Rats; Rats, Wistar; Triglycerides | 2018 |
Effect of l-carnitine and mildronate on the mitochondrial metabolism of heart and bacterial composition of the gut microbiome in ageing mice.
Topics: Aging; Animals; Bifidobacterium; Cardiovascular Agents; Carnitine; DNA, Mitochondrial; Female; Gastrointestinal Microbiome; Male; Methylhydrazines; Mice; Mice, Inbred C57BL; Mitochondria, Heart | 2022 |