carmustine and phenobarbital

carmustine has been researched along with phenobarbital in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19908 (47.06)18.7374
1990's3 (17.65)18.2507
2000's3 (17.65)29.6817
2010's3 (17.65)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Byrd, A; Finn, A; Levin, VA; Stearns, J; Weinkam, RJ1
Mehendale, HM; Utley, WS2
Larson, RE; Stolzenbach, JC1
Ayala, A; F-Lobato, M; Machado, A1
Farber, JL; Kyle, ME; Nakae, D; Serroni, A1
Kanter, PM; Schwartz, HS; West, CR1
Albani, F; Baruzzi, A; Bollini, C; Bollini, P; Cacciari, L; Ida, N; Riva, R1
Larson, RE; Moldowan, MJ; Wilson, VL1
Larson, RE; Wilson, VL1
Lin, HS; Weinkam, RJ1

Other Studies

17 other study(ies) available for carmustine and phenobarbital

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
The effect of phenobarbital pretreatment on the antitumor activity of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU), 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) and 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidyl-1-nitrosourea (PCNU), and on the plasma p
    The Journal of pharmacology and experimental therapeutics, 1979, Volume: 208, Issue:1

    Topics: Alkylating Agents; Animals; Biotransformation; Brain Neoplasms; Carmustine; Dexamethasone; Drug Interactions; In Vitro Techniques; Kinetics; Liver; Lomustine; Male; Methylprednisolone; Neoplasms, Experimental; Nitrosourea Compounds; Phenobarbital; Phenytoin; Rats; Rats, Inbred F344

1979
Phenobarbital-induced cytoprotective mechanisms in menadione metabolism: the role of glutathione reductase and DT-diaphorase.
    The International journal of biochemistry, 1990, Volume: 22, Issue:9

    Topics: Animals; Carmustine; Cell Survival; Dicumarol; Drug Interactions; Glutathione Reductase; Kinetics; Liver; Male; NAD(P)H Dehydrogenase (Quinone); Phenobarbital; Quinone Reductases; Rats; Rats, Inbred Strains; Superoxides; Vitamin K

1990
Evidence for stimulated glutathione synthesis by phenobarbital pretreatment during an oxidative challenge in isolated hepatocytes.
    Journal of biochemical toxicology, 1991,Summer, Volume: 6, Issue:2

    Topics: Animals; Buthionine Sulfoximine; Carmustine; Glutathione; Glutathione Reductase; Homeostasis; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Male; Methionine Sulfoximine; Oxidation-Reduction; Phenobarbital; Rats; Rats, Inbred Strains; Trypan Blue; Vitamin K

1991
BCNU-induced quantitative and qualitative changes in hepatic cytochrome P-450 can be correlated with cholestasis.
    Cancer chemotherapy and pharmacology, 1990, Volume: 25, Issue:4

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Carmustine; Cholestasis; Cytochrome P-450 Enzyme System; Electrophoresis, Disc; Endoplasmic Reticulum; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; Molecular Weight; Organ Size; Phenobarbital; Rats; Rats, Inbred Strains

1990
Malic enzyme levels are increased by the activation of NADPH-consuming pathways: detoxification processes.
    FEBS letters, 1986, Jun-23, Volume: 202, Issue:1

    Topics: Adipose Tissue; Animals; Carmustine; Enzyme Activation; Female; Glutathione Reductase; Immunochemistry; Inactivation, Metabolic; Malate Dehydrogenase; NADP; NADPH-Ferrihemoprotein Reductase; Peroxides; Phenobarbital; Rats; Rats, Inbred Strains; tert-Butylhydroperoxide

1986
1,3-(2-Chloroethyl)-1-nitrosourea potentiates the toxicity of acetaminophen both in the phenobarbital-induced rat and in hepatocytes cultured from such animals.
    Molecular pharmacology, 1988, Volume: 34, Issue:4

    Topics: Acetaminophen; Acetone; Carmustine; Cell Survival; Deferoxamine; Drug Synergism; Enzyme Induction; Glutathione; Liver; Male; Maleates; Methylcholanthrene; Phenobarbital; Phenylenediamines

1988
Functional and chemical markers of PCNU activity.
    Cancer drug delivery, 1983, Volume: 1, Issue:1

    Topics: Animals; Antineoplastic Agents; Carmustine; DNA; Humans; Leukemia; Mice; Nitrosourea Compounds; Phenobarbital; Thymidine

1983
Decreased phenytoin level during antineoplastic therapy: a case report.
    Epilepsia, 1983, Volume: 24, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Drug Interactions; Drug Therapy, Combination; Humans; Male; Methotrexate; Middle Aged; Phenobarbital; Phenytoin; Seizures; Vinblastine

1983
A non-invasive method for the study of hepatic drug metabolism in rodents: antineoplastic drug effects on antipyrine metabolism in mice.
    Chemico-biological interactions, 1982, Volume: 40, Issue:2

    Topics: Aminopyrine; Animals; Antineoplastic Agents; Antipyrine; Carmustine; Half-Life; Liver; Male; Mice; Pharmaceutical Preparations; Phenobarbital; Rats; Rats, Inbred Strains; Saliva

1982
Responsiveness of Carmustine (BCNU) treated mice to induction and inhibition of mixed function oxygenases.
    Research communications in chemical pathology and pharmacology, 1982, Volume: 36, Issue:3

    Topics: Animals; Carmustine; Cytochrome P-450 Enzyme System; Enzyme Induction; Male; Mice; Mice, Inbred Strains; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital

1982
Metabolism of 1,3-bis(2-chloroethyl)-1-nitrosourea by rat hepatic microsomes.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:6

    Topics: Animals; Carmustine; In Vitro Techniques; Kinetics; Lomustine; Male; Microsomes, Liver; NADP; Phenobarbital; Rats; Rats, Inbred F344

1981