carmustine and nimustine

carmustine has been researched along with nimustine in 45 studies

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-199016 (35.56)18.7374
1990's15 (33.33)18.2507
2000's9 (20.00)29.6817
2010's5 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Fan, T; Sun, G; Zhang, N; Zhang, S; Zhao, L; Zhong, R1
Lai, X; Ren, T; Sun, G; Wang, Y; Zhang, N; Zhao, L; Zhong, R1
Darling, JL; Hoffmann, O; Kraemer, HP; Nikkhah, G; Schachenmayr, W; Schönmayr, R; Tonn, JC1
Roosen, K; Schachenmayr, W; Tonn, JC1
Dahl, O; Schem, BC1
Erbersdobler, A; Gassmann, W; Glass, B; Löffler, H; Mueller-Ruchholtz, W; Schmitz, N; Uharek, L; Wottge, HU1
Arita, N; Bitoh, S; Hasegawa, H; Hayakawa, T; Ikeda, H; Kanai, N; Kanoh, M; Mogami, H; Oku, Y; Ushio, Y1
Heuser, K1
Kraemer, HP; Schönmayr, R; Tonn, JC2
Fields, WS; Iwata, K; Yung, WK1
Bamberg, M; Budach, W; Sprengel, M; Strehl, K; Stuschke, M1
Jaksche, H; Loew, F; Papavero, L1
Aida, T1
Ishii, H1
Bamberg, M; Budach, V; Gerhard, L; Stuschke, M1
Aida, T; Bodell, WJ2
Kamiya, S1
Aida, T; Berger, MS; Bodell, WJ; Gerosa, M; Rosenblum, ML1
Bosanquet, AG1
Hayakawa, T; Mogami, H; Nakata, Y; Sakamoto, Y; Shimizu, K; Ushio, Y; Yoshida, T2
Wakui, A1
Oguro, M; Takenaga, K; Yanagawa, T1
Krossnes, BK; Mella, O; Roszinski, S; Schem, BC1
Kuratsu, J; Ushio, Y1
Chen, JM; Chen, YN; Fan, GC; He, T; Wu, Y; Xu, HY; Zhang, YP1
Fujioka, K; Funabiki, T; Ikuta, K; Kai, S; Kajigaya, Y; Matsuyama, S; Sakai, H; Sekiguchi, H; Sumita, H; Takahashi, H1
Nemoto, S1
Kohda, K; Terashima, I1
Damian, MS; Leweke, F; Schachenmayr, W; Schindler, C1
Makhova, EV; Moshkovskaia, EIu; Vasil'eva, SV1
Weller, M; Winter, S1
Bardenheuer, W; Flasshove, M; Jansen, M; Moritz, T; Seeber, S; Sorg, UR1
Boiardi, A; Eoli, M; Erbetta, A; Fariselli, L; Salmaggi, A; Silvani, A1
Zhang, YP1
Shibui, S1
Berrak, S; Koontz Webb, SE; Wolff, JE; Zhang, M1
Ogawa, M; Ueda, T; Yamauchi, T1
Bekö, SL; Glaubitz, C; Lakatos, A; Schmidt, MU; Urmann, D1
Allgayer, H; Fruehauf, S; Heckmann, D; Laufs, S; Maier, P; Spier, I; Wenz, F; Zeller, WJ; Zucknick, M1
Kanamori, M; Kumabe, T; Mano, Y; Saito, R; Sonoda, Y; Tominaga, T; Zhang, R1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1

Reviews

5 review(s) available for carmustine and nimustine

ArticleYear
Stability of solutions of antineoplastic agents during preparation and storage for in vitro assays. General considerations, the nitrosoureas and alkylating agents.
    Cancer chemotherapy and pharmacology, 1985, Volume: 14, Issue:2

    Topics: Alkylation; Antineoplastic Agents; Carmustine; Chlorambucil; Colony-Forming Units Assay; Cyclophosphamide; Drug Storage; Hydrogen-Ion Concentration; Lomustine; Mathematics; Melphalan; Nimustine; Nitrosourea Compounds; Solutions; Temperature; Tumor Stem Cell Assay

1985
[Cancer chemotherapy with special reference to pharmacokinetics of nitrosoureas].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1982, Volume: 9, Issue:8

    Topics: Carmustine; Humans; Kinetics; Lomustine; Neoplasms; Nimustine; Nitrosourea Compounds; Semustine; Solubility; Streptozocin

1982
[Chemotherapy of brain tumors].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21 Suppl 3

    Topics: Blood-Brain Barrier; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Combined Modality Therapy; Glioma; Humans; Nimustine

1994
[Study on MGMT assay and tumor individual predictable chemotherapy].
    Ai zheng = Aizheng = Chinese journal of cancer, 2004, Volume: 23, Issue:6

    Topics: Alkylating Agents; Animals; Antineoplastic Agents; Brain Neoplasms; Carmustine; Drug Resistance, Neoplasm; HeLa Cells; Humans; Mice; Mice, Nude; Neoplasms; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Reagent Kits, Diagnostic; RNA, Messenger

2004
[Treatment for malignant glioma].
    No to shinkei = Brain and nerve, 2005, Volume: 57, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Clinical Trials, Phase III as Topic; Combined Modality Therapy; Glioma; Humans; Nimustine

2005

Trials

3 trial(s) available for carmustine and nimustine

ArticleYear
Chemotherapy of brain metastases from lung carcinoma: a controlled randomized study.
    Neurosurgery, 1991, Volume: 28, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Carmustine; Combined Modality Therapy; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nimustine; Radiotherapy Dosage; Remission Induction; Semustine; Survival Rate; Tegafur

1991
[High-dose busulfan, VP-16 and ACNU therapy with stem cell transplantation for the treatment of children with acute leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1993, Volume: 34, Issue:5

    Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Carmustine; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Male; Nimustine

1993
Intra-arterial ACNU and carboplatin versus intravenous chemotherapy with cisplatin and BCNU in newly diagnosed patients with glioblastoma.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2002, Volume: 23, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carmustine; Cisplatin; Drug Administration Routes; Female; Glioblastoma; Humans; Injections, Intra-Arterial; Injections, Intravenous; Karnofsky Performance Status; Male; Middle Aged; Nimustine

2002

Other Studies

37 other study(ies) available for carmustine and nimustine

ArticleYear
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Synthesis and antitumor activity evaluation of a novel combi-nitrosourea prodrug: Designed to release a DNA cross-linking agent and an inhibitor of O(6)-alkylguanine-DNA alkyltransferase.
    Bioorganic & medicinal chemistry, 2016, May-01, Volume: 24, Issue:9

    Topics: Antineoplastic Agents; Cross-Linking Reagents; Enzyme Inhibitors; Humans; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase; Prodrugs

2016
Synthesis and Antitumor Activity Evaluation of a Novel Combi-nitrosourea Prodrug: BGCNU.
    ACS medicinal chemistry letters, 2017, Feb-09, Volume: 8, Issue:2

    Topics:

2017
The MTT assay for chemosensitivity testing of human tumors of the central nervous system. Part II: Evaluation of patient- and drug-specific variables.
    Journal of neuro-oncology, 1992, Volume: 13, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cell Survival; Colony-Forming Units Assay; Coloring Agents; Drug Screening Assays, Antitumor; Glioma; Humans; Mitomycin; Mitoxantrone; Nimustine; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

1992
Brain necroses after intraarterial chemotherapy and irradiation of malignant gliomas--a complication of both ACNU and BCNU?
    Journal of neuro-oncology, 1991, Volume: 11, Issue:3

    Topics: Brain; Brain Diseases; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Combined Modality Therapy; Cranial Irradiation; Glioma; Humans; Infusions, Intravenous; Injections, Intra-Arterial; Necrosis; Nimustine; Prospective Studies; Radiation Injuries

1991
Thermal enhancement of ACNU and potentiation of thermochemotherapy with ACNU by hypertonic glucose in the BT4An rat glioma.
    Journal of neuro-oncology, 1991, Volume: 10, Issue:3

    Topics: Animals; Brain Neoplasms; Carmustine; Combined Modality Therapy; Drug Screening Assays, Antitumor; Drug Synergism; Glioma; Glucose; Hydrogen-Ion Concentration; Hyperthermia, Induced; Hypertonic Solutions; Neoplasm Transplantation; Nimustine; Rats; Rats, Inbred Strains; Retinal Diseases; Skin Neoplasms; Tumor Cells, Cultured

1991
High-dose cytostatic agents in allogeneic bone marrow transplantation: comparison of the engraftment promoting potential.
    British journal of haematology, 1991, Volume: 78, Issue:3

    Topics: Animals; Antineoplastic Agents; Bone Marrow Transplantation; Carboplatin; Carmustine; Cyclophosphamide; Graft Rejection; Ifosfamide; Immunosuppression Therapy; Male; Melphalan; Nimustine; Rats; Rats, Inbred Lew; Thiotepa

1991
[Chemotherapy in malignant gliomas].
    Neurochirurgia, 1990, Volume: 33 Suppl 1

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Combined Modality Therapy; Cytarabine; Follow-Up Studies; Glioma; Humans; Nimustine; Survival Rate; Teniposide

1990
Sensitivity of human malignant intracranial tumors against MCNU in vitro in comparison to ACNU and BCNU.
    Journal of neuro-oncology, 1990, Volume: 8, Issue:1

    Topics: Aged; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Drug Screening Assays, Antitumor; Female; Glioma; Humans; Male; Middle Aged; Nimustine; Nitrosourea Compounds; Tumor Cells, Cultured

1990
In vitro effects of ACNU, BCNU, CDDP, and bleomycin on human glioma cells.
    Neurologia medico-chirurgica, 1988, Volume: 28, Issue:10

    Topics: Antineoplastic Agents; Bleomycin; Brain Neoplasms; Carmustine; Cell Line; Cisplatin; Drug Screening Assays, Antitumor; Glioblastoma; Humans; Nimustine; Tumor Cells, Cultured

1988
Treatment of high grade glioma xenografts with nitrosoureas in nude mice.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1989, Volume: 165, Issue:7

    Topics: Animals; Carmustine; Glioblastoma; Glioma; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Nimustine; Oligodendroglioma; Transplantation, Heterologous

1989
Intracarotid infusion of ACNU and BCNU as adjuvant therapy of malignant gliomas. Clinical aspects and critical considerations.
    Acta neurochirurgica, 1987, Volume: 85, Issue:3-4

    Topics: Astrocytoma; Brain Neoplasms; Carmustine; Carotid Arteries; Combined Modality Therapy; Follow-Up Studies; Glioblastoma; Glioma; Humans; Infusions, Intra-Arterial; Neoplasm Recurrence, Local; Nimustine; Nitrosourea Compounds; Oligodendroglioma

1987
[Mechanisms of cellular resistance to chloroethylnitrosourea in cell lines derived from human brain tumors].
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1988, Volume: 63, Issue:3

    Topics: Brain Neoplasms; Carmustine; Cell Line; DNA Damage; Drug Resistance; Glioma; Humans; Nimustine; Nitrosourea Compounds; Sister Chromatid Exchange; Tumor Cells, Cultured

1988
Combination chemotherapy for multiple myeloma with melphalan, ifosfamide, prednisolone, nitrosourea and vincristine.
    Acta medica Okayama, 1988, Volume: 42, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Female; Humans; Ifosfamide; Male; Melphalan; Middle Aged; Multiple Myeloma; Neoplasm Staging; Nimustine; Nitrosourea Compounds; Prednisolone; Prognosis; Vincristine

1988
Preliminary experimental results with the nitrosourea derivative ACNU in the treatment of malignant gliomas.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1988, Volume: 12, Issue:1

    Topics: Animals; Astrocytoma; Carmustine; Disease Models, Animal; Dose-Response Relationship, Drug; Lethal Dose 50; Mice; Mice, Nude; Nimustine; Nitrosourea Compounds; Oligodendroglioma; Transplantation, Heterologous

1988
Cellular resistance to chloroethylnitrosoureas, nitrogen mustard, and cis-diamminedichloroplatinum(II) in human glial-derived cell lines.
    Cancer research, 1987, Mar-01, Volume: 47, Issue:5

    Topics: Carmustine; Cell Line; Cell Survival; Cisplatin; DNA; Dose-Response Relationship, Drug; Drug Resistance; Glioma; Humans; Mechlorethamine; Methylation; Nimustine; Nitrosourea Compounds; Sister Chromatid Exchange

1987
[Synthesis of antitumor nitrosourea derivatives and chemical studies of their mechanism of action].
    Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences, 1986, Issue:104

    Topics: Antineoplastic Agents; Bone Marrow; Carmustine; Humans; Lomustine; Nimustine; Nitroso Compounds; Nitrosourea Compounds

1986
[Anticancer drug induced sister chromatid exchange and correlation to cell survival in human brain tumor cells].
    No to shinkei = Brain and nerve, 1987, Volume: 39, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cell Line; Cell Survival; Cisplatin; Glioma; Humans; Mechlorethamine; Nimustine; Nitrosourea Compounds; Sister Chromatid Exchange; Tumor Stem Cell Assay

1987
Investigation of resistance to DNA cross-linking agents in 9L cell lines with different sensitivities to chloroethylnitrosoureas.
    Cancer research, 1985, Volume: 45, Issue:8

    Topics: Animals; Antineoplastic Agents; Carmustine; Cell Line; Cell Survival; Cross-Linking Reagents; DNA; DNA Repair; Drug Resistance; Nimustine; Nitrosourea Compounds; Rats; Sister Chromatid Exchange

1985
[Chemotherapy of experimental meningeal gliomatosis].
    Neurologia medico-chirurgica, 1984, Volume: 24, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brain; Carmustine; Glioma; Male; Meningeal Neoplasms; Nimustine; Nitrosourea Compounds; Rats; Rats, Inbred F344; Rats, Inbred Strains

1984
[Meningeal gliomatosis models as a chemosensitivity assay system].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:3

    Topics: Animals; Antineoplastic Agents; Carmustine; Cell Division; Cell Survival; Disease Models, Animal; Drug Resistance; Glioma; Male; Meningeal Neoplasms; Nimustine; Nitrosourea Compounds; Rats; Rats, Inbred F344; Rats, Inbred Strains

1984
[Antitumor activity of a new nitrosourea, MCNU, on a cellular morphological basis evaluated by a new in vitro antitumor sensitivity assay].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:12 Pt 1

    Topics: Animals; Antineoplastic Agents; Carmustine; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance; Humans; In Vitro Techniques; Leukemia L1210; Lomustine; Nimustine; Nitrosourea Compounds; Semustine; Tumor Stem Cell Assay

1984
Timing of hypertonic glucose and thermochemotherapy with 1-(4-amino-2-methylpyrimidine-5-yl) methyl-3-(2-chloroethyl)-3-nitrosourea (ACNU) in the BT4An rat glioma: relation to intratumoral pH reduction and circulatory changes after glucose supply.
    International journal of radiation oncology, biology, physics, 1995, Sep-30, Volume: 33, Issue:2

    Topics: Animals; Antineoplastic Agents; Carmustine; Combined Modality Therapy; Drug Administration Schedule; Glioblastoma; Glucose Solution, Hypertonic; Hydrogen-Ion Concentration; Hyperthermia, Induced; Nimustine; Rats; Rats, Inbred Strains; Tumor Cells, Cultured

1995
[Specific curative effects of nitrosourea drugs on tumor cells with Mer--phenotype in Chinese].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1993, Volume: 14, Issue:6

    Topics: Animals; Carmustine; Female; Humans; Liver Neoplasms; Methyltransferases; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Phenotype; Tumor Cells, Cultured; Uterine Cervical Neoplasms

1993
[Intravascular surgery for brain tumors].
    No to shinkei = Brain and nerve, 1993, Volume: 45, Issue:5

    Topics: Brain Neoplasms; Carmustine; Chemoembolization, Therapeutic; Humans; Meningeal Neoplasms; Meningioma; Nimustine

1993
Cytotoxicity of fluoroethylating agents is potentiated by O6-benzylguanine.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:7

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Carmustine; Cell Survival; Drug Synergism; Guanine; HeLa Cells; Humans; Iodoacetamide; Lomustine; Nimustine

1996
Multidrug resistance in glioblastoma. Chemosensitivity testing and immunohistochemical demonstration of P-glycoprotein.
    Pathology, research and practice, 1998, Volume: 194, Issue:3

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain Neoplasms; Carmustine; Cell Survival; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Glioblastoma; Immunohistochemistry; Methotrexate; Mitoxantrone; Nimustine; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

1998
[Expression and functions of adaptive response genes in Escherichia coli treated with mono- and bifunctional alkylating agents. Interference with SOS response].
    Genetika, 1999, Volume: 35, Issue:4

    Topics: Adaptation, Physiological; Antineoplastic Agents, Alkylating; Biological Evolution; Carmustine; Escherichia coli; Gene Expression Regulation, Bacterial; Nimustine; Operon; SOS Response, Genetics

1999
Poly(ADP-ribose) polymerase-independent potentiation of nitrosourea cytotoxicity by 3-aminobenzamide in human malignant glioma cells.
    European journal of pharmacology, 2000, Jun-16, Volume: 398, Issue:2

    Topics: Benzamides; Binding Sites; Carmustine; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; G2 Phase; Glioma; Humans; Lomustine; Methylnitrosourea; Mitosis; Nimustine; Nitrosourea Compounds; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Tumor Cells, Cultured

2000
Protection of hematopoietic cells from O(6)-alkylation damage by O(6)-methylguanine DNA methyltransferase gene transfer: studies with different O(6)-alkylating agents and retroviral backbones.
    European journal of haematology, 2001, Volume: 67, Issue:1

    Topics: Alkylating Agents; Alkylation; Animals; Carmustine; Cells, Cultured; Colony-Forming Units Assay; Dacarbazine; DNA Damage; DNA, Complementary; Drug Resistance; Genetic Vectors; Hematopoietic Stem Cells; Humans; Lomustine; Mice; Moloney murine leukemia virus; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Recombinant Fusion Proteins; Retroviridae; Sarcoma Viruses, Murine; Spleen Focus-Forming Viruses; Temozolomide; Terminal Repeat Sequences; Transfection

2001
Resistance of human malignant intracranial tumors in vitro: potential guidelines to clinical therapy?
    Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:4 Suppl

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cell Division; Drug Resistance, Neoplasm; Humans; Models, Biological; Nimustine; Tumor Cells, Cultured

1989
Nitrosourea efficacy in high-grade glioma: a survival gain analysis summarizing 504 cohorts with 24193 patients.
    Journal of neuro-oncology, 2008, Volume: 88, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Cohort Studies; Data Interpretation, Statistical; Databases, Factual; Female; Glioblastoma; Glioma; Humans; Lomustine; Male; Nimustine; Nitrosourea Compounds; Reproducibility of Results; Selection Bias; Survival Analysis; Treatment Outcome

2008
Carmustine-resistant cancer cells are sensitized to temozolomide as a result of enhanced mismatch repair during the development of carmustine resistance.
    Molecular pharmacology, 2008, Volume: 74, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cadmium Chloride; Carmustine; Cell Line, Tumor; Cell Proliferation; Comet Assay; Dacarbazine; DNA Mismatch Repair; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Guanine; Humans; Hydroxylamines; Nimustine; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Temozolomide

2008
Nimustine hydrochloride: the first crystal structure determination of a 2-chloroethyl-N-nitrosourea hydrochloride derivative by X-ray powder diffraction and solid-state NMR.
    Acta crystallographica. Section C, Crystal structure communications, 2012, Volume: 68, Issue:Pt 3

    Topics: Carmustine; Crystallography, X-Ray; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Models, Molecular; Nimustine; Powders; X-Ray Diffraction

2012
F2A sequence linking MGMT(P140K) and MDR1 in a bicistronic lentiviral vector enables efficient chemoprotection of haematopoietic stem cells.
    Cancer gene therapy, 2012, Volume: 19, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carmustine; Cell Survival; Cloning, Molecular; Cytoprotection; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Doxorubicin; Genetic Vectors; Hematopoietic Stem Cells; HL-60 Cells; Humans; K562 Cells; Lentivirus; Nimustine; Paclitaxel; Peptides; Real-Time Polymerase Chain Reaction; Temozolomide; Transgenes; Tumor Suppressor Proteins

2012
Concentration rather than dose defines the local brain toxicity of agents that are effectively distributed by convection-enhanced delivery.
    Journal of neuroscience methods, 2014, Jan-30, Volume: 222

    Topics: Animals; Antineoplastic Agents; Brain; Carmustine; Convection; Corpus Striatum; Diffusion; Dose-Response Relationship, Drug; Doxorubicin; Drug Delivery Systems; Immunohistochemistry; Male; Nimustine; Polyethylene Glycols; Rats, Inbred F344

2014
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007