carmustine and nadp

carmustine has been researched along with nadp in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199014 (42.42)18.7374
1990's12 (36.36)18.2507
2000's6 (18.18)29.6817
2010's0 (0.00)24.3611
2020's1 (3.03)2.80

Authors

AuthorsStudies
Shinohara, K; Tanaka, KR1
Hill, DL; Kirk, MC; Struck, RF1
Brodie, AE; Reed, DJ1
Rao, P; Zigler, JS1
Farber, JL; Yamamoto, K1
Lenartowicz, E1
Miller, RM; Park, EM; Thomas, JA1
Frischer, H; Hohl, RJ; Kennedy, EJ1
Bauman, C; FitzGerald, GB; Hussoin, MS; Wick, MM1
Jones, DP; Tribble, DL1
Ayala, A; F-Lobato, M; Machado, A1
Jackson, JH; McMurtry, IF; Repine, JE; White, CW1
Kim, G; Kramer, RA; Zakher, J1
Fabregat, I; Machado, A; Revilla, E1
Alberts, DW; Rush, GF; Smith, PF1
Eklöw-Låstbom, L; Moldéus, P; Orrenius, S1
DeSantis, N; Solomon, F; Winkler, BS1
Ahmad, T; Frischer, H1
Reed, DJ1
Eklöw, L; Moldéus, P; Orrenius, S1
Potter, DW; Reed, DJ1
Lin, HS; Weinkam, RJ1
Aw, TY; Rhoads, CA1
Waxman, DJ; Weber, GF1
Kehrer, JP; Liu, H1
Chakraborti, S; Chakraborti, T; Ghosh, JJ; Ghosh, SK; Roychoudhury, S1
Adachi, T; Cohen, RA1
Bhamre, S; Cohen, HJ; Nuzzo, RL; Olshen, RA; Whitin, JC1
Adam-Vizi, V; Tretter, L1
Carlson, L; Dwivedi, C; Guan, X; Herman, J; Peitz, G; Seefeldt, T; Zhang, Z1
Krause, WJ; Manandhar, G; Miranda-Vizuete, A; Pedrajas, JR; Sutovsky, M; Sutovsky, P; Zimmerman, S1
Funakoshi, M; Ishii, K; Ogasawara, Y1
Aliverti, A; de Rosa, M; Nonnis, S1

Other Studies

33 other study(ies) available for carmustine and nadp

ArticleYear
Mechanism of inhibition of red blood cell glutathione reductase activity by BCNU (1,3-bis(2-chloroethyl)-1-nitrosourea).
    Clinica chimica acta; international journal of clinical chemistry, 1979, Mar-01, Volume: 92, Issue:2

    Topics: Carmustine; Erythrocytes; Ethylmaleimide; Glutathione; Glutathione Reductase; Humans; In Vitro Techniques; Mercaptoethanol; NADP

1979
Microsomal metabolism of nitrosoureas.
    Cancer research, 1975, Volume: 35, Issue:2

    Topics: Animals; Binding, Competitive; Carbon Radioisotopes; Carmustine; Cell Fractionation; Chemical Phenomena; Chemistry; Cyclohexanes; Cyclophosphamide; Female; In Vitro Techniques; Lung; Mass Spectrometry; Mice; Mice, Inbred DBA; Microsomes, Liver; Mixed Function Oxygenases; NADP; Nicotine; Nitrosourea Compounds

1975
Glutathione disulfide reduction in tumor mitochondria after t-butyl hydroperoxide treatment.
    Chemico-biological interactions, 1992, Sep-28, Volume: 84, Issue:2

    Topics: Adenosine Diphosphate; Animals; Antimycin A; Carmustine; Glutathione; Glutathione Disulfide; Glutathione Reductase; Ketoglutaric Acids; Liver Neoplasms, Experimental; Malates; Mitochondria, Liver; NADP; Oxidation-Reduction; Peroxides; Rats; Rats, Sprague-Dawley; Succinates; Succinic Acid; tert-Butylhydroperoxide

1992
Quinone induced stimulation of hexose monophosphate shunt activity in the guinea pig lens: role of zeta-crystallin.
    Biochimica et biophysica acta, 1992, Mar-05, Volume: 1116, Issue:1

    Topics: Animals; Carmustine; Crystallins; Dose-Response Relationship, Drug; Guinea Pigs; Hydrogen Peroxide; Lens, Crystalline; NADP; Naphthoquinones; Organ Culture Techniques; Pentose Phosphate Pathway; Rats; Rats, Inbred Strains

1992
Metabolism of pyridine nucleotides in cultured rat hepatocytes intoxicated with tert-butyl hydroperoxide.
    Biochemical pharmacology, 1992, Mar-03, Volume: 43, Issue:5

    Topics: Animals; Benzamides; Carmustine; Cell Death; Cells, Cultured; Deferoxamine; Drug Interactions; Hydrogen Peroxide; Liver; Male; NAD; NADP; Peroxides; Phenylenediamines; Rats; Rats, Inbred Strains; tert-Butylhydroperoxide; Time Factors

1992
Ca(2+)-sensitive reduction of 5,5'-dithiobis-(2-nitrobenzoic acid) by rat liver mitochondria.
    Biochemical and biophysical research communications, 1992, Apr-30, Volume: 184, Issue:2

    Topics: Animals; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Carmustine; Dithionitrobenzoic Acid; Edetic Acid; Kinetics; Magnesium; Mitochondria, Liver; NADP; Oxidation-Reduction; Rats; Spermine

1992
Reduction (dethiolation) of protein mixed-disulfides; distribution and specificity of dethiolating enzymes and N,N'-bis(2-chlorethyl)-N-nitrosourea inhibition of an NADPH-dependent cardiac dethiolase.
    Archives of biochemistry and biophysics, 1991, May-15, Volume: 287, Issue:1

    Topics: Animals; Carmustine; Cattle; Disulfides; Glutaredoxins; Mice; NADH, NADPH Oxidoreductases; NADP; Organ Specificity; Oxidation-Reduction; Oxidoreductases; Prohibitins; Proteins; Rabbits; Rats; Solubility; Substrate Specificity; Thioredoxins

1991
Defenses against oxidation in human erythrocytes: role of glutathione reductase in the activation of glucose decarboxylation by hemolytic drugs.
    The Journal of laboratory and clinical medicine, 1991, Volume: 117, Issue:4

    Topics: Carbon Dioxide; Carmustine; Decarboxylation; Erythrocytes; Glucose; Glucosephosphate Dehydrogenase Deficiency; Glutathione Reductase; Hemolysis; Humans; NADP; Oxidation-Reduction; Pentose Phosphate Pathway

1991
2,4-Dihydroxybenzylamine: a specific inhibitor of glutathione reductase.
    Biochemical pharmacology, 1991, Jan-15, Volume: 41, Issue:2

    Topics: Binding Sites; Binding, Competitive; Carmustine; Catechols; Dithioerythritol; Dose-Response Relationship, Drug; Glutathione; Glutathione Reductase; Models, Chemical; NADP

1991
Oxygen dependence of oxidative stress. Rate of NADPH supply for maintaining the GSH pool during hypoxia.
    Biochemical pharmacology, 1990, Feb-15, Volume: 39, Issue:4

    Topics: Animals; Carmustine; Citrates; Citric Acid; Diamide; Glucose; Glutathione; Glutathione Reductase; Hypoxia; Kinetics; Liver; Male; NADP; Oxidation-Reduction; Oxygen; Rats; Sulfhydryl Compounds

1990
Malic enzyme levels are increased by the activation of NADPH-consuming pathways: detoxification processes.
    FEBS letters, 1986, Jun-23, Volume: 202, Issue:1

    Topics: Adipose Tissue; Animals; Carmustine; Enzyme Activation; Female; Glutathione Reductase; Immunochemistry; Inactivation, Metabolic; Malate Dehydrogenase; NADP; NADPH-Ferrihemoprotein Reductase; Peroxides; Phenobarbital; Rats; Rats, Inbred Strains; tert-Butylhydroperoxide

1986
Hypoxia increases glutathione redox cycle and protects rat lungs against oxidants.
    Journal of applied physiology (Bethesda, Md. : 1985), 1988, Volume: 65, Issue:6

    Topics: 6-Aminonicotinamide; Animals; Carmustine; Glutathione; Hydrogen Peroxide; Hypoxia; In Vitro Techniques; Lung; Lung Injury; Male; NADP; Oxidation-Reduction; Pentose Phosphate Pathway; Pulmonary Edema; Rats; Rats, Inbred Strains

1988
Role of the glutathione redox cycle in acquired and de novo multidrug resistance.
    Science (New York, N.Y.), 1988, Aug-05, Volume: 241, Issue:4866

    Topics: Animals; Carmustine; Colonic Neoplasms; Doxorubicin; Drug Resistance; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Humans; Leukemia P388; Mice; NADP; Oxidation-Reduction; Phenotype; Rectal Neoplasms; Tumor Cells, Cultured; Verapamil

1988
The NADPH consumption regulates the NADPH-producing pathways (pentose phosphate cycle and malic enzyme) in rat adipocytes.
    Molecular and cellular biochemistry, 1987, Volume: 74, Issue:1

    Topics: Adipose Tissue; Animals; Carmustine; Female; Kinetics; Kynurenic Acid; Malate Dehydrogenase; NADP; Oxidation-Reduction; Pentose Phosphate Pathway; Peroxides; Rats; Rats, Inbred Strains; tert-Butylhydroperoxide

1987
Role of glutathione reductase during menadione-induced NADPH oxidation in isolated rat hepatocytes.
    Biochemical pharmacology, 1987, Nov-15, Volume: 36, Issue:22

    Topics: Animals; Carmustine; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Glutathione Reductase; Liver; Male; NADP; Oxidation-Reduction; Rats; Rats, Inbred Strains; Time Factors; Vitamin K

1987
On the mechanisms of glutathione depletion in hepatocytes exposed to morphine and ethylmorphine.
    Toxicology, 1986, Dec-01, Volume: 42, Issue:1

    Topics: Animals; Carmustine; Ethylmorphine; Glutathione; Glutathione Reductase; Hexobarbital; Hydrogen Peroxide; Liver; Male; Morphine; Morphine Derivatives; NADP; Rats; Rats, Inbred Strains

1986
Multiple NADPH-producing pathways control glutathione (GSH) content in retina.
    Experimental eye research, 1986, Volume: 43, Issue:5

    Topics: Animals; Carmustine; Cold Temperature; Diamide; Glucose; Glutathione; Glutathione Reductase; In Vitro Techniques; Isocitrate Dehydrogenase; Malate Dehydrogenase; NADP; Oxidation-Reduction; Pentose Phosphate Pathway; Pyruvates; Rats; Retina

1986
Active site-specific inhibition by 1,3-bis(2-chloroethyl)-1-nitrosourea of two genetically homologous flavoenzymes: glutathione reductase and lipoamide dehydrogenase.
    The Journal of laboratory and clinical medicine, 1985, Volume: 105, Issue:4

    Topics: Carmustine; Dihydrolipoamide Dehydrogenase; Drug Interactions; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Glutathione Reductase; Humans; In Vitro Techniques; NADP; Oxidation-Reduction; Oxidoreductases; Thioctic Acid

1985
Regulation of reductive processes by glutathione.
    Biochemical pharmacology, 1986, Jan-01, Volume: 35, Issue:1

    Topics: Animals; Carmustine; Cell Survival; Diamide; Doxorubicin; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Humans; Leukemia L5178; Lipid Peroxides; Liver; Mice; NADP; Oxidation-Reduction

1986
Oxidation of glutathione during hydroperoxide metabolism. A study using isolated hepatocytes and the glutathione reductase inhibitor 1,3-bis(2-chloroethyl)-1-nitrosourea.
    European journal of biochemistry, 1984, Feb-01, Volume: 138, Issue:3

    Topics: Animals; Carmustine; Glutathione; Glutathione Reductase; Hydrogen Peroxide; In Vitro Techniques; Liver; Male; NADP; Oxidation-Reduction; Rats; Rats, Inbred Strains

1984
Denitrosation of carcinostatic nitrosoureas by purified NADPH cytochrome P-450 reductase and rat liver microsomes to yield nitric oxide under anaerobic conditions.
    Archives of biochemistry and biophysics, 1982, Volume: 216, Issue:1

    Topics: Anaerobiosis; Animals; Biotransformation; Carmustine; Kinetics; Lomustine; Microsomes, Liver; NADP; NADPH-Ferrihemoprotein Reductase; Nitric Oxide; Nitrosourea Compounds; Oxidation-Reduction; Rats; Rats, Inbred Strains; Spectrophotometry

1982
Metabolism of 1,3-bis(2-chloroethyl)-1-nitrosourea by rat hepatic microsomes.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:6

    Topics: Animals; Carmustine; In Vitro Techniques; Kinetics; Lomustine; Male; Microsomes, Liver; NADP; Phenobarbital; Rats; Rats, Inbred F344

1981
Glucose regulation of hydroperoxide metabolism in rat intestinal cells. Stimulation of reduced nicotinamide adenine dinucleotide phosphate supply.
    The Journal of clinical investigation, 1994, Volume: 94, Issue:6

    Topics: 6-Aminonicotinamide; Animals; Carmustine; Dose-Response Relationship, Drug; Glucose; Glutathione; Inactivation, Metabolic; Intestinal Mucosa; Intestines; Male; NADP; Oxidation-Reduction; Pentose Phosphate Pathway; Peroxides; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; tert-Butylhydroperoxide

1994
Denitrosation of the anti-cancer drug 1,3-bis(2-chloroethyl)-1-nitrosourea catalyzed by microsomal glutathione S-transferase and cytochrome P450 monooxygenases.
    Archives of biochemistry and biophysics, 1993, Volume: 307, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Carmustine; Coenzymes; Cyclophosphamide; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Female; Glutathione Transferase; Ifosfamide; Liver; Male; Microsomes, Liver; NADP; NADPH-Ferrihemoprotein Reductase; Oxidoreductases; Oxygenases; Phosphoramide Mustards; Proadifen; Rats

1993
The reduction of glutathione disulfide produced by t-butyl hydroperoxide in respiring mitochondria.
    Free radical biology & medicine, 1996, Volume: 20, Issue:3

    Topics: Animals; Antimycin A; Ascorbic Acid; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Carmustine; Glutathione; Glutathione Disulfide; Kinetics; Male; Mitochondria, Liver; NAD; NADP; Oligomycins; Oxidation-Reduction; Oxygen Consumption; Peroxides; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Rotenone; Succinates; tert-Butylhydroperoxide; Time Factors; Uncoupling Agents

1996
Redox state of pyridine nucleotides, but not glutathione, regulate Ca2+ release by H2O2 from mitochondria of pulmonary smooth muscle.
    Indian journal of biochemistry & biophysics, 1996, Volume: 33, Issue:3

    Topics: Animals; Calcium; Carmustine; Cattle; Electron Transport Complex IV; Glutathione; Hydrogen Peroxide; Kinetics; Mitochondria; Muscle, Smooth, Vascular; NAD; NADP; Oxaloacetates; Oxidation-Reduction; Pulmonary Artery

1996
Decreased aortic glutathione levels may contribute to impaired nitric oxide-induced relaxation in hypercholesterolaemia.
    British journal of pharmacology, 2000, Volume: 129, Issue:5

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Carmustine; Diamide; Diet, Atherogenic; Glutathione; Hypercholesterolemia; Isometric Contraction; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NADP; Nitric Oxide; Nitroprusside; Oxidants; Rabbits; Sulfhydryl Reagents; Vasodilator Agents

2000
Intracellular reduction of selenite into glutathione peroxidase. Evidence for involvement of NADPH and not glutathione as the reductant.
    Molecular and cellular biochemistry, 2000, Volume: 211, Issue:1-2

    Topics: Animals; Buthionine Sulfoximine; Carmustine; Cell Line; Cricetinae; Enzyme Inhibitors; Glucosephosphate Dehydrogenase; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Humans; Male; Methylene Blue; NADP; Oxidation-Reduction; Sodium Selenite; Tumor Cells, Cultured

2000
Inhibition of Krebs cycle enzymes by hydrogen peroxide: A key role of [alpha]-ketoglutarate dehydrogenase in limiting NADH production under oxidative stress.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, Dec-15, Volume: 20, Issue:24

    Topics: Aconitate Hydratase; Animals; Carmustine; Cerebral Cortex; Citrate (si)-Synthase; Citric Acid Cycle; Dose-Response Relationship, Drug; Electron Transport; Enzyme Activation; Glucose; Glutamic Acid; Glutathione Reductase; Guinea Pigs; Hydrogen Peroxide; Ketoglutarate Dehydrogenase Complex; Malate Dehydrogenase; NAD; NADP; Oxidative Stress; Pyrimidines; Rotenone; Spectrometry, Fluorescence; Succinate Dehydrogenase; Synaptosomes

2000
2-Acetylamino-3-[4-(2-acetylamino-2-carboxyethylsulfanylcarbonylamino)- phenylcarbamoylsulfanyl]propionic acid and its derivatives as a novel class of glutathione reductase inhibitors.
    Journal of medicinal chemistry, 2005, Aug-11, Volume: 48, Issue:16

    Topics: Carmustine; Cysteine; Glutathione Reductase; Kinetics; NADP; Solubility; Structure-Activity Relationship; Thiocarbamates

2005
Peroxiredoxin 2 and peroxidase enzymatic activity of mammalian spermatozoa.
    Biology of reproduction, 2009, Volume: 80, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Cytoplasm; Hydrogen Peroxide; Immunohistochemistry; Male; Mice; NADP; Peroxidases; Peroxiredoxins; Solubility; Sperm Head; Spermatids; Swine; Testis

2009
Determination of reduced nicotinamide adenine dinucleotide phosphate concentration using high-performance liquid chromatography with fluorescence detection: ratio of the reduced form as a biomarker of oxidative stress.
    Biological & pharmaceutical bulletin, 2009, Volume: 32, Issue:11

    Topics: Biomarkers; Blood Glucose; Carmustine; Chromatography, High Pressure Liquid; Glutathione; Humans; NADP; Oxidation-Reduction; Oxidative Stress; Spectrometry, Fluorescence

2009
Covalent inhibition of P. falciparum ferredoxin-NADP
    Biochemical and biophysical research communications, 2021, 11-05, Volume: 577

    Topics: Antineoplastic Agents, Alkylating; Biocatalysis; Carmustine; Catalytic Domain; Cysteine; Diamide; Enzyme Inhibitors; Ferredoxin-NADP Reductase; Kinetics; Malaria, Falciparum; Molecular Structure; NADP; Organomercury Compounds; Plasmodium falciparum; Protein Binding; Protein Domains; Protozoan Proteins; Substrate Specificity

2021