carmustine and misonidazole

carmustine has been researched along with misonidazole in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199022 (78.57)18.7374
1990's6 (21.43)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Levin, VA1
Scavone, SV; Sebolt-Leopold, JS1
Urano, M; Wong, KH1
Wallen, CA; Wheeler, KT; Wong, KH; Zhang, H1
Wallen, CA; Wheeler, KT; Wong, KH3
Burger, PC; Deutsch, M; Green, SB; Mealey, J; Paoletti, P; Ransohoff, J; Robertson, JT; Selker, RG; Shapiro, WR; Strike, TA1
Gutin, PH; Nelson, DF; Saunders, WM; Sheline, GE; Urtasun, RC1
Diener-West, M; Nelson, DF; Pakuris, E; Weinstein, AS1
Carabell, S; Chang, CH; Diener-West, M; Goodman, R; Nelson, DF; Nelson, JS; Sause, WT; Schoenfeld, D; Weinstein, AS1
Mulcahy, RT; Siemann, DW2
Mulcahy, RT; Siemann, DW; Sutherland, RM2
Adams, GE1
Lee, FY; Workman, P1
Carabell, S; Goodman, RL; Nelson, DF; Nelson, JS; Schoenfeld, D; Wasserman, T; Weinstein, AS1
Siemann, DW; Wallen, CA; Wheeler, KT; Wolf, KL1
Morrissey, S; Siemann, DW; Wheeler, KT; Wolf, K1
Dembs, N; Mulcahy, RT1
Csejtey, J; Landahl, HD; Levin, VA; Patlak, CS; Wright, DC1
Siemann, DW1
Clutterbuck, RD; McElwain, TJ; Millar, JL1
Allen, N1
Twentyman, PR1
Tannock, IF1
Abbott, NJ; Chan, MW; Ray, DE; Romero, IA1

Reviews

2 review(s) available for carmustine and misonidazole

ArticleYear
Recent and current investigations of radiation therapy of malignant gliomas.
    Seminars in oncology, 1986, Volume: 13, Issue:1

    Topics: Brachytherapy; Brain; Brain Neoplasms; Bromodeoxyuridine; Carmustine; Glioma; Helium; Humans; Hyperbaric Oxygenation; Hyperthermia, Induced; Mesons; Metronidazole; Middle Aged; Misonidazole; Neon; Neutrons; Radiation-Sensitizing Agents; Radiotherapy; Radiotherapy, High-Energy

1986
Potentiation of chemotherapy by hypoxic cell radiation sensitizers--a review.
    International journal of radiation oncology, biology, physics, 1982, Volume: 8, Issue:6

    Topics: Anaerobiosis; Animals; Antineoplastic Agents; Carmustine; Cyclophosphamide; Drug Synergism; Lomustine; Mice; Misonidazole; Neoplasms, Experimental; Radiation-Sensitizing Agents

1982

Trials

4 trial(s) available for carmustine and misonidazole

ArticleYear
Results of a randomized trial comparing BCNU plus radiotherapy, streptozotocin plus radiotherapy, BCNU plus hyperfractionated radiotherapy, and BCNU following misonidazole plus radiotherapy in the postoperative treatment of malignant glioma.
    International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:6

    Topics: Adolescent; Adult; Aged; Astrocytoma; Carmustine; Combined Modality Therapy; Glioblastoma; Glioma; Humans; Middle Aged; Misonidazole; Multicenter Studies as Topic; Prognosis; Radiotherapy Dosage; Random Allocation; Streptozocin; Supratentorial Neoplasms

1989
Pulmonary toxicity of carmustine in patients treated for malignant glioma.
    Cancer treatment reports, 1986, Volume: 70, Issue:8

    Topics: Adult; Aged; Carmustine; Clinical Trials as Topic; Combined Modality Therapy; Dose-Response Relationship, Drug; Female; Glioma; Humans; Lung Diseases; Male; Middle Aged; Misonidazole; Random Allocation; Risk

1986
A randomized comparison of misonidazole sensitized radiotherapy plus BCNU and radiotherapy plus BCNU for treatment of malignant glioma after surgery: final report of an RTOG study.
    International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:10

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Combined Modality Therapy; Glioma; Humans; Middle Aged; Misonidazole; Prognosis; Radiation-Sensitizing Agents; Random Allocation

1986
A randomized comparison of misonidazole sensitized radiotherapy plus BCNU and radiotherapy plus BCNU for treatment of malignant glioma after surgery; preliminary results of an RTOG study.
    International journal of radiation oncology, biology, physics, 1983, Volume: 9, Issue:8

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Drug Administration Schedule; Glioma; Humans; Middle Aged; Misonidazole; Nitroimidazoles; Prospective Studies; Radiation-Sensitizing Agents; Random Allocation

1983

Other Studies

22 other study(ies) available for carmustine and misonidazole

ArticleYear
Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:6

    Topics: Animals; Blood-Brain Barrier; Brain; Capillary Permeability; Male; Models, Biological; Molecular Weight; Rats; Rats, Inbred F344; Solubility; Structure-Activity Relationship

1980
Enhancement of alkylating agent activity in vitro by PD 128763, a potent poly(ADP-ribose) synthetase inhibitor.
    International journal of radiation oncology, biology, physics, 1992, Volume: 22, Issue:3

    Topics: Alkylating Agents; Animals; Carmustine; Drug Synergism; In Vitro Techniques; Isoquinolines; Leukemia L1210; Misonidazole; Poly(ADP-ribose) Polymerase Inhibitors; Streptozocin; Tumor Cells, Cultured

1992
Enhancement of misonidazole chemosensitization effect by mild local hyperthermia.
    International journal of radiation oncology, biology, physics, 1992, Volume: 23, Issue:3

    Topics: Animals; Carmustine; Cyclophosphamide; Hyperthermia, Induced; Mice; Mice, Inbred C3H; Misonidazole; Neoplasms, Experimental

1992
Effect of administration schedules on the potentiation of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) by misonidazole in subcutaneous 9L tumors.
    International journal of radiation oncology, biology, physics, 1992, Volume: 23, Issue:4

    Topics: Animals; Carmustine; Drug Synergism; Male; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Rats, Inbred F344; Survival Rate

1992
2-Nitroimidazole potentiation of nitrosourea induced cytotoxicity in subcutaneous implants of rat 9L brain tumor cells.
    Journal of neuro-oncology, 1991, Volume: 11, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cell Line; Cell Survival; Drug Synergism; Etanidazole; Lomustine; Male; Misonidazole; Nitroimidazoles; Rats; Rats, Inbred F344; Streptozocin; Tumor Stem Cell Assay

1991
Chemosensitization of the nitrosoureas by 2-nitroimidazoles in the subcutaneous 9L tumor model: pharmacokinetic and structure-activity considerations.
    International journal of radiation oncology, biology, physics, 1990, Volume: 18, Issue:5

    Topics: Animals; Carmustine; Drug Synergism; Etanidazole; Lomustine; Male; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Nitrosourea Compounds; Rats; Rats, Inbred F344; Structure-Activity Relationship

1990
Biodistribution of misonidazole and 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) in rats bearing unclamped and clamped 9L subcutaneous tumors.
    International journal of radiation oncology, biology, physics, 1989, Volume: 17, Issue:1

    Topics: Animals; Biological Availability; Carmustine; Constriction; Drug Interactions; Half-Life; Male; Misonidazole; Neoplasms, Experimental; Rats; Rats, Inbred F344; Regional Blood Flow; Tissue Distribution

1989
Sensitization of cancer chemotherapeutic agents by nitroheterocyclics.
    Biochemical pharmacology, 1986, Jan-01, Volume: 35, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cell Survival; Drug Synergism; Heterocyclic Compounds; Hydroxamic Acids; Hypoxia; Lomustine; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents

1986
Nitrosourea-misonidazole combination chemotherapy: effect on KHT sarcomas, marrow stem cells and gut.
    British journal of cancer, 1982, Volume: 45, Issue:6

    Topics: Animals; Antineoplastic Agents; Carmustine; Cell Survival; Cells, Cultured; Colony-Forming Units Assay; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Sarcoma, Experimental; Streptozocin

1982
Radiosensitizers: a conference preview.
    International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:8

    Topics: Animals; Aziridines; Buthionine Sulfoximine; Carmustine; Combined Modality Therapy; Drug Synergism; Etanidazole; Humans; Ketones; Lomustine; Maleates; Methionine Sulfoximine; Mice; Misonidazole; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents

1984
Nitroimidazoles as modifiers of nitrosourea pharmacokinetics.
    International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:9

    Topics: Animals; Antineoplastic Agents; Carmustine; Lomustine; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Nitrosourea Compounds; Radiation-Sensitizing Agents; Semustine; Streptozocin; Time Factors

1984
Hypoxic cells and in situ chemopotentiation of the nitrosoureas by misonidazole.
    British journal of cancer, 1984, Volume: 49, Issue:6

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Lomustine; Misonidazole; Nitroimidazoles; Oxygen; Rats; Skin Neoplasms; Tumor Stem Cell Assay

1984
In vitro potentiation of BCNU activity in rat brain tumour cells pretreated with misonidazole.
    British journal of cancer, 1984, Volume: 49, Issue:6

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Survival; Cells, Cultured; Drug Synergism; Misonidazole; Nitroimidazoles; Rats

1984
Time-dose relationships for simultaneous misonidazole and 1,3-bis(2-chloroethyl)-1-nitrosourea exposures in vitro.
    Cancer research, 1983, Volume: 43, Issue:8

    Topics: Animals; Carmustine; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Fibrosarcoma; Mice; Misonidazole; Nitroimidazoles; Time Factors

1983
In vivo chemosensitization by misonidazole in sensitive and resistant tumor lines.
    Cancer research, 1983, Volume: 43, Issue:10

    Topics: Animals; Carmustine; Cell Line; Drug Resistance; Drug Synergism; Humans; Leukemia L1210; Lomustine; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Nitrosourea Compounds; Sarcoma, Experimental

1983
In situ drug delivery.
    The British journal of cancer. Supplement, 1980, Volume: 4

    Topics: Animals; Capillaries; Carmustine; Half-Life; Misonidazole; Models, Biological; Neoplasms, Experimental; Nitroimidazoles; Rats

1980
Misonidazole enhancement of the action of BCNU and melphalan against human melanoma xenografts.
    American journal of clinical oncology, 1982, Volume: 5, Issue:1

    Topics: Animals; Antineoplastic Agents; Bone Marrow; Carmustine; Cell Line; Drug Synergism; Drug Therapy, Combination; Female; Humans; Male; Melanoma; Melphalan; Mice; Mice, Inbred CBA; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Transplantation, Heterologous

1982
Experimental therapy of brain tumors.
    Progress in clinical and biological research, 1980, Volume: 39

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Line; Methods; Metronidazole; Misonidazole; Neoplasms, Experimental; Radiation-Sensitizing Agents; Rats; Sulfhydryl Compounds; Vitamin A

1980
The response of EMT6 tumor spheroids to combined treatment with misonidazole and either nitrogen mustard, adriamycin, or BCNU.
    Cancer clinical trials, 1980,Fall, Volume: 3, Issue:3

    Topics: Animals; Antineoplastic Agents; Carmustine; Cell Survival; Dose-Response Relationship, Drug; Doxorubicin; In Vitro Techniques; Mammary Neoplasms, Experimental; Mechlorethamine; Mice; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents

1980
In vivo interaction of anti-cancer drugs with misonidazole or metronidazole: cyclophosphamide and BCNU.
    British journal of cancer, 1980, Volume: 42, Issue:6

    Topics: Animals; Body Weight; Carmustine; Cyclophosphamide; Drug Therapy, Combination; Fibrosarcoma; Leukocyte Count; Male; Mammary Neoplasms, Experimental; Metronidazole; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Sarcoma, Experimental

1980
In vivo response of KHT sarcomas to combination chemotherapy with radiosensitizers and BCNU.
    British journal of cancer, 1981, Volume: 43, Issue:1

    Topics: Animals; Carmustine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Sarcoma, Experimental; Time Factors

1981
Increased oxidative metabolism and oxidative stress in m-dinitrobenzene neurotoxicity.
    Biochemical Society transactions, 1994, Volume: 22, Issue:4

    Topics: Animals; Animals, Newborn; Astrocytes; Brain; Carmustine; Cell Survival; Cells, Cultured; Deferoxamine; Dinitrobenzenes; Glutathione; Glutathione Disulfide; Glycolysis; L-Lactate Dehydrogenase; Lactates; Male; Misonidazole; Neurotoxins; Nitrofurazone; Oxidative Stress; Rats; Rats, Inbred F344

1994