carmustine and lomustine

carmustine has been researched along with lomustine in 235 studies

Research

Studies (235)

TimeframeStudies, this research(%)All Research%
pre-1990172 (73.19)18.7374
1990's31 (13.19)18.2507
2000's17 (7.23)29.6817
2010's13 (5.53)24.3611
2020's2 (0.85)2.80

Authors

AuthorsStudies
Clayton, SD; Frye, JL; Johnston, TP; Krauth, CA; McCaleb, GS; Montgomery, JA1
Johnston, TP; Laster, WR; Mayo, JG; McCaleb, GS; Montgomery, JA1
Dolan, ME; Weinkam, RJ1
Levin, VA1
Hansch, C; Jow, PY; Leo, A; Montgomery, JA; Schmidt, C1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Benfenati, E; Raska, I; Toropov, AA; Toropova, AP1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bleehen, NM; Twentyman, PR2
Bruntsch, U1
Twentyman, PR1
Murphy, GP; Sufrin, G1
Rao, AP; Rao, PN1
Walker, MD2
Bhuyan, BK; Day, KJ; Fraser, TJ1
Fox, P; Green, D; Nagourney, R; Panasci, LC; Schein, PS1
Kann, HE1
Ewig, RA; Kohn, KW2
Bradley, MO; Erickson, LC; Kohn, KW1
Eisenbrand, G; Fiebig, HH; Zeller, WJ1
Moertel, CG3
Bono, VH1
Livingston, RB1
Boldrey, EB; Drafts, D; Enot, KJ; Gutin, P; Levin, VA; Wilson, CB1
Campbell, RJ; Laws, ER; Saez, RJ1
Schmidt, CG1
Bonadonna, G; Brambilla, C; Monfardini, S; Morello, G; Solero, CL; Vaghi, A; Valagussa, P2
Hassoun, J; Paillas, JE; Pellet, W; Peragut, JC; Prince, MA1
Burgert, EO; Cuttner, J; Degnan, T; Del Duca, V; Falkson, G; Freeman, A; Hakami, N; Holland, J; Koch, K; Kung, FH; Lanzkowsky, P; Leone, LA; Nawabi, IU; Nythan, WL; Pajak, TF; Patterson, RB; Pluess, H; Ruymann, F1
Auletta, AE; Martz, AG; Parmar, AS1
Knerich, R; Paoletti, P; Robustelli della Cuna, G; Strada, MR1
Albert, ED; Bender-Gotze, C; Grosse-Wilde, H; Kolb, HJ; Lieven, HV; Thiel, E; Wundisch, GF1
McIntyre, OR1
Bistoni, F; Bonmassar, E; Frati, L; Goldin, A; Marconi, P; Pitzurra, M; Spreafico, F1
Baldini, M; Knerich, R; Paoletti, P; Princi, L1
Barlogie, B; Drewinko, B; Freireich, EJ1
Corbett, TH; Griswold, DP; Schabel, FM; Venditti, JM; Wolpert, MK1
Lin, HS; Weinkam, RJ2
Deen, DF; Wheeler, KT; Williams, ME1
Begleiter, A; Goldenberg, GJ; Lam, HP1
Fumagalli, R; Paoletti, P; Pezzotta, S; Weiss, JF1
Koós, R; Krauze, I; Péter, A; Schuler, D1
Fumagalli, R; Paoletti, P; Pezzotta, S; Racca, AR2
Goldin, A1
Bono, VH; Louie, AC; Muggia, FM; Turrisi, AT1
Levin, VA; Wilson, CB3
Freeman-Dove, MA; Kabra, PA; Levin, VA1
Byrd, A; Finn, A; Levin, VA; Stearns, J; Weinkam, RJ1
Comis, RL1
Hill, G; Johnson, RO; Krementz, E; Metter, G; Wilson, W1
Carbone, PP; Costello, W1
Marsh, JC1
Schabel, FM1
Ahmann, DL1
Wolf, J1
Bartolucci, A; Dorfman, RF; Durant, JR; Gams, RA; Velez-Garcia, E1
Salmon, SE2
Cruz, AB; Davis, HL; Fletcher, WS; Golomb, FM; Grage, T; Hill, GJ; Johnson, RO; Metter, G; Wilson, WL1
Oliverio, VT1
Kohn, KW1
Aranha, GV; Grage, TB1
Wilson, CB1
Brundrett, RB; Colvin, M; Cowens, W; Jardine, I; Ludlum, DB1
Wasserman, TH1
Hilton, J; Walker, MD1
Balis, E; Brisman, R; Chang, C; Duffy, P; Housepian, EM1
Slavik, M1
Carter, RD; Fletcher, WS; Golomb, FM; Grage, TB; Hill, GJ; Krementz, ET; Metter, GE; Minton, JP; Sparks, FC1
Chuang, RY; Keller, P; Laszlo, J1
Carter, SK; Slavik, M; Wasserman, TH1
James, R; Johnston, TP; Kirk, MC; McCaleb, GS; Montgomery, JA1
Epstein, EH; Zackheim, HS1
Carter, SK1
Drewinko, B; Gottlieb, JA; Loo, TL1
Camus, P; Coudert, B; Foucher, P; Jeannin, L; Lombard, JN; Massin, F; Reybet-Degat, O1
Aziz Rani, A; Chudahman, M; Dharmika, D; Ismail Ali, A; Simadibrata, R1
Dolan, ME; Mitchell, RB; Moschel, RC; Mummert, C; Pegg, AE1
Matthay, RA; Twohig, KJ1
Glover, DJ1
Dolan, ME; Mitchell, RB; Moschel, RC1
Bizzari, JP; Fillastre, JP; Hemet, J; Laquerriere, A; Paraire, M; Paresy, M; Raguenez-Viotte, G1
Wallen, CA; Wheeler, KT; Wong, KH2
Gattamaneni, HR; Ogilvy-Stuart, AL; Shalet, SM1
Davis, RL; Gutin, PH; Hannigan, J; Levin, VA; Silver, P; Wara, WM; Wilson, CB1
Durand, RE1
Bradford, R; Darling, JL; Sier, N; Thomas, DG1
Bradford, R; Darling, JL; Thomas, DG1
Bizzari, JP; Deloffre, P; Etienne, MC; Fischel, JL; Formento, P; Frenay, M; Gioanni, J; Milano, G1
Brajtburg, J; Elberg, S; Medoff, G; Schechtman, KB1
Assietti, R; Butti, G; Gaetani, P; Knerich, R; Paoletti, P1
Anderson, SP; Briscoe, WT; May, HE1
Brent, TP; Smith, DG1
Gerson, SL1
Clayton, PE; Jones, PH; Price, DA; Shalet, SM1
Clyde, C; Dolan, ME; Erickson, LC; Hora, NK; Norbeck, L; Pegg, AE1
Bodell, WJ; Doane-Setzer, P; Evans, CG; Smith, MT; Tokuda, K1
Dive, C; Watson, JV; Workman, P1
Giles, RC; Harrison, SD; Mann, DM1
Kapp, JP; Vance, RB1
Davis, RL; Gutin, PH; Levin, VA; Nutik, S; Resser, KJ; Vestnys, P; Wara, WM; Wilson, CB; Yatsko, K1
Bricolo, A; Della Corte, V; Gerosa, MA; Licata, C; Marcon, C; Rosenblum, ML; Stevanoni, G; Tridente, G1
Brunner, K; Coleman, M; Cooper, MR; Cornwell, GG; Glowienka, LP; Henderson, E; Kochwa, S; McIntyre, OR; Pajak, TF; Rafla, S1
Holden, SA; Rose, CM; Teicher, BA1
Cassady, JR; Hughes, EN; Loeffler, JS; Sallan, SE; Shillito, J; Tarbell, NJ1
Campbell, RH; Clayton, PE; Price, DA; Shalet, SM1
Morimoto, RI; Schaefer, EL; Seidenfeld, J; Theodorakis, NG1
El-Yazigi, A; Martin, CR1
Brajtburg, J; Elberg, S; Kobayashi, GS; Medoff, G1
Adamson, DJ; Brockman, RW; Elliott, RD; Montgomery, JA; Riordan, JM; Shaddix, SC; Thomas, HJ1
Cairncross, JG; Macdonald, DR1
Kamiya, S1
Phillips, GL; Reece, DE1
Denkel, E; Eisenbrand, G; Müller, N; Sterzel, W1
Ludlum, DB1
Godlewski, A; Szczech, J1
Dean, PN; Deen, DF; Gray, JW; Linfoot, PA; Marton, LJ1
Carpenter, L; Hill, GJ; Hill, HZ; Lea, MA; Luke, A; Martinson, CF; Velazquez, O1
Kovatch, RM; Lijinsky, W; Singer, SS1
Powell, SR; Puglia, CD1
Chessa, A; Desogus, A; Floris, C; Muggiano, A; Sulis, E; Tedde, A; Turno, R1
Bosanquet, AG1
Ozhiganov, EL; Platinskiĭ, LV; Sokolova, VD1
Mulcahy, RT; Siemann, DW2
Adams, K; Peacock, JH; Stephens, TC1
Bleehen, NM; Honess, DJ1
Baril, B; Baril, E; Laszlo, J1
Brugerie, E; Huong, TH; Lheritier, J; Pouillart, R1
Kessinger, A1
Huang, AT; Lucas, VS; Pickett, NJ; Seigler, HF1
Gamsu, G; Putman, CE; Sostman, HD1
Bloomfield, CD; Coleman, M; Glicksman, AS; Glidewell, OJ; Gottlieb, AJ; Holland, JF; Nissen, NI; Pajak, TF; Rafla, S; Stutzman, L; Vinciguerra, V1
Heim, ME; Queisser, W1
Rice, LS; Shannon, WM; Suling, WJ1
Wakui, A1
Glatte, P; Osieka, R; Pannenbäcker, R; Schmidt, CG1
deKernion, JB; Lindner, A1
Adams, GE1
Lee, FY; Workman, P1
Bernardo, G; Butti, G; Cuzzoni, Q; Knerich, R; Paoletti, P; Robustelli della Cuna, G1
Erickson, LC; Zlotogorski, C1
Biron, P; Dutou, L; Ehrsam, A; Hervé, P; Le Mevel, A; Philip, I; Philip, T; Philippe, N; Plouvier, E; Souillet, G1
Hill, GJ; Hill, HZ; Krementz, ET1
Preussmann, R1
Fingert, HJ; Hochberg, FH1
Deen, DF; Marton, LJ; Oredsson, SM1
Kann, HE; Petkas, A; Schott, MA1
Hoth, D; Macdonald, JS; Schein, PS1
Mutzner, F1
Bartosek, I; Cattaneo, MT; Russo, RG1
Bernaudin, JF; Cordonnier, C; Lange, F; Mital, P; Rochant, H; Vernant, JP1
Dieckman, J; Medoff, G; Valeriote, F1
Oguro, M; Takenaga, K; Yanagawa, T1
Brannan, TS; Maker, HS; Weiss, C1
Erickson, LC; Kohn, KW; Sariban, E1
Siemann, DW; Wallen, CA; Wheeler, KT; Wolf, KL1
Shapiro, WR1
Issell, BF; Weiss, RB1
Robak, T1
Potter, DW; Reed, DJ1
Gropp, C; Havemann, K1
Brunner, K; Cuttner, J; Falkson, G; Hansen, HH; Holland, JF; Nissen, NI; Pajak, TF; Selawry, OS; Spurr, CL1
Levin, VA; Vestnys, PS; Wilson, CB1
Siemann, DW1
Chin, HW; Maruyama, Y; Muir, W; Young, AB1
Deen, DF; Weinkam, RJ1
Buoncristiani, P; Casotto, A1
Brunner, K; Cooper, MR; Cornwell, GG; Cuttner, J; Glowienka, LP; Haurani, FI; Henderson, E; Kochwa, S; Kyle, RA; McIntyre, OR; Pajak, TF; Rafla, S; Silver, RT1
Kohn, KW; Ludlum, DB; Tong, WP1
Gibson, NW; Hickman, JA1
Gombar, CT; Ludlum, DB; Tong, WP1
Chauhan, SM; Lown, JW1
Blackstock, SC; Cheung, LK; Loo, TL; Smith, RG1
Baldwin, DS; Feiner, HD; Gallo, GR; Lieberman, A; Schacht, RG1
Eisenbrand, G; Habs, M1
Gordy, DD; Murray, JL; Robertson, DM; Wilkinson, CP1
Babson, JR; Brodie, AE; Reed, DJ1
Finn, A; Kane, JP; Levin, VA; Weinkam, RJ1
Smuckler, EA; Zackheim, HS1
Finkel, JM; Hill, DL; Kari, P; McConnell, WR1
Cenci, E; Perito, S; Sbaraglia, G; Vecchiarelli, A1
Ardiet, C; Lind, MJ1
Gazdar, AF; Ghosh, BC; Ihde, DC; Johnson, BE; Linnoila, RI; Minna, JD; Mulshine, JL; Oie, HK; Pass, HI; Phelps, R; Russell, EK; Shaw, GL; Steinberg, SM1
Kohda, K; Terashima, I1
Mennel, HD; Ruschoff, J; Schlegel, J; Stumm, G1
Allison, RR; Barry, T; Schulsinger, A; Shin, KH; Vongtama, V1
Adler, ID; Ehling, UH; Favor, J; Neuhäuser-Klaus, A1
Ahmed, MM; Albores-Saavedra, J; Delgado, R; Fruitwala, MM; Kokkinakis, DM; Mohiuddin, M1
Golovinsky, E; Gugova, R; Staleva, L; Venkov, P; Waltscheva, L1
Gundersen, S; Lote, K; Watne, K1
Bass, G; Bloxham, D; Gandhi, MK; Jestice, K; Marcus, RE; Scott, MA1
Devereux, S; Goldstone, AH; Gregory, W; Hancock, B; Harrison, CN; Hoskin, P; Hudson, GV; Linch, DC; MacMillan, AK; Milligan, D; Newland, AC; Winfield, D1
Curran, WJ; Kramer, S; Leibel, S; Nelson, DF; Prados, MD; Scott, C1
Penketh, PG; Sartorelli, AC; Shyam, K1
Weller, M; Winter, S1
Boiardi, A; Broggi, G; Eoli, M; Pozzi, A; Salmaggi, A; Silvani, A1
Hung, CF1
Bardenheuer, W; Flasshove, M; Jansen, M; Moritz, T; Seeber, S; Sorg, UR1
Blume, KG; Chao, NS; Horning, SJ; Johnston, LJ; Long, GD; Negrin, RS; Shizuru, JA; Stockerl-Goldstein, KE; Stuart, MJ; Wong, RM1
Mo, H; Ou, G; Qin, D1
Eisen, TG; Lens, MB1
Jung, SM; Liau, CT; Tseng, CK; Wei, KC1
Berrak, S; Koontz Webb, SE; Wolff, JE; Zhang, M1
Ansell, S; Arndt, C; Buckner, J; Christianson, T; Galanis, E; Gill, P; Litzow, M; Moynihan, T1
Kobiakov, GL1
Deray, G; Isnard-Bagnis, C; Janus, N; Karie, S; Launay-Vacher, V1
Amarasingh, S; Macleod, MR; Whittle, IR1
Kartashev, AV; Vinogradov, VM1
Filatova, LV; Gershanovich, ML1
Nishikawa, R1
Kim, JH; Kim, ST; Kim, WS; Kong, DS; Kwon, KH; Lee, JI; Lim, DH; Nam, DH; Park, K; Suh, YL1
Audrain, O; Carsin, B; Gedouin, D; Hamlat, A; Lecouillard, I; Lesimple, T; Louvel, G; Mesbah, H; Quillien, V; Riffaud, L; Vauleon, E1
Ahmed, AB; Bruserud, O; Hatfield, KJ; Kittang, AO; Reikvam, H; Sjo, M; Tvedt, TH1
Brodbelt, A; Mallucci, C; Pizer, B; Salehzadeh, A1
Alexander, BM; Beroukhim, R; Doherty, L; Hempfling, K; Huang, RY; LaFrankie, D; Lee, EQ; Nayak, L; Norden, AD; Rahman, R; Rai, A; Reardon, DA; Rifenburg, J; Rinne, ML; Ruland, S; Wen, PY1
Abuali, I; Grossman, SA; Lu, Y; Strowd, RE; Ye, X1
Gore, A; Gupta, A; Jain, R; Jeevangi, N; Kannan, S; Khattry, N; Nair, R; Saikia, T; Thippeswamy, R1
Ardeshna, KM; Foley, M; Kothari, J; Lambert, J; Linch, DC; Mackenzie, S; Morris, E; Peggs, KS; Thomson, K; Virchis, AE1
Bettarello, G; Costa, LJM; da Matta Abreu, M; Dos Santos, KB; Hallack Neto, AE; Mayrink, GTC; Mota, MA; Pereira, J; Ribeiro, LC1
Kelsey, P; Kirkland, K; Lambert, J; Malladi, R; Morley, N; Paul, R; Pearce, R; Peniket, A; Perry, J; Snowden, JA1
Awortwe, C; Cascorbi, I; Kaehler, M; Majchrzak-Celińska, A; Nagel, I; Radtke, L; Sebens, S; Vater, I1

Reviews

28 review(s) available for carmustine and lomustine

ArticleYear
Review of mechanism of action studies of the nitrosoureas.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Alkylating Agents; Animals; Bone Marrow; Bone Marrow Cells; Carmustine; Cell Division; Cell Survival; DNA; DNA, Neoplasm; Ethyl Chloride; Lomustine; Mice; NAD+ Nucleosidase; Neoplasms, Experimental; Nitrosourea Compounds; Protein Biosynthesis; RNA; Semustine; Streptozocin

1976
Current concepts in cancer. Multiple myeloma.
    The New England journal of medicine, 1979, Jul-26, Volume: 301, Issue:4

    Topics: Antineoplastic Agents; Carmustine; Cyclophosphamide; Drug Therapy, Combination; Humans; Immunoglobulins; Lomustine; Melphalan; Multiple Myeloma; Neoplasm Staging; Plasmapheresis; Prednisone; Risk; Sodium Fluoride; Uremia

1979
DTIC (NSC-45388) in malignant melanoma: a perspective.
    Cancer treatment reports, 1976, Volume: 60, Issue:2

    Topics: Animals; Antineoplastic Agents; Carmustine; Clinical Trials as Topic; Dacarbazine; Drug Evaluation; Drug Therapy, Combination; Humans; Lomustine; Melanoma; Mice; Neoplasm Metastasis; Nitrosourea Compounds; Remission, Spontaneous; Triazenes

1976
The effects of cancer chemotherapeutic agents on normal hematopoietic precursor cells: a review.
    Cancer research, 1976, Volume: 36, Issue:6

    Topics: Alkylating Agents; Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Asparaginase; Benzamides; Busulfan; Carmustine; Cisplatin; Cyclophosphamide; Cytarabine; Drug Evaluation, Preclinical; Erythrocytes; Fluorouracil; Hematopoietic Stem Cells; Humans; Hydroxyurea; Lomustine; Methotrexate; Nitrogen Mustard Compounds; Spleen; Vinca Alkaloids

1976
Nitrosoureas: a review of experimental antitumor activity.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Animals; Carmustine; Colonic Neoplasms; Drug Evaluation, Preclinical; Drug Resistance; Drug Therapy, Combination; Leukemia L1210; Lomustine; Lung Neoplasms; Mammary Neoplasms, Experimental; Melanoma; Methylnitronitrosoguanidine; Methylnitrosourea; Mice; Neoplasms, Experimental; Nitrosourea Compounds; Semustine

1976
Chemotherapy: the agents in current use.
    Seminars in oncology, 1975, Volume: 2, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Dacarbazine; Drug Therapy, Combination; Glioma; Humans; Lomustine; Medulloblastoma; Methotrexate; Nitrogen Mustard Compounds; Procarbazine; Semustine; Teniposide; Vincristine

1975
Clinical comparison of the nitrosoureas.
    Cancer, 1975, Volume: 36, Issue:4

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Breast Neoplasms; Carmustine; Chemical Phenomena; Chemistry; Colonic Neoplasms; Drug Therapy, Combination; Hodgkin Disease; Humans; Lomustine; Lung Neoplasms; Lymphoma; Melanoma; Methylnitrosourea; Mice; Neoplasms, Experimental; Nitrosourea Compounds; Rectal Neoplasms

1975
[Nitrosourea-induced lung diseases].
    Revue des maladies respiratoires, 1992, Volume: 9, Issue:6

    Topics: Adult; Brain Neoplasms; Carmustine; Child; Drug Therapy, Combination; Female; Humans; Iatrogenic Disease; Lomustine; Lung; Lung Diseases; Nitrosourea Compounds; Pneumonia; Prognosis; Pulmonary Fibrosis; Risk Factors; Semustine

1992
Pulmonary effects of cytotoxic agents other than bleomycin.
    Clinics in chest medicine, 1990, Volume: 11, Issue:1

    Topics: Antineoplastic Agents; Bleomycin; Busulfan; Carmustine; Cyclophosphamide; Humans; Lomustine; Methotrexate; Mitomycins; Pulmonary Fibrosis; Vinblastine; Vindesine

1990
Clinical studies of autologous bone marrow transplantation in Hodgkin's disease.
    Clinics in haematology, 1986, Volume: 15, Issue:1

    Topics: Alkylating Agents; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation; Carmustine; Cell Separation; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Drug Resistance; Etoposide; Hodgkin Disease; Humans; Lomustine; Pulmonary Fibrosis; Risk; Thioguanine; Transplantation, Autologous; Whole-Body Irradiation

1986
DNA adducts and DNA damage by antineoplastic and carcinogenic N-nitrosocompounds.
    Journal of cancer research and clinical oncology, 1986, Volume: 112, Issue:3

    Topics: Alkylation; Animals; Antineoplastic Agents; Carcinogens; Carmustine; Chemical Phenomena; Chemistry; DNA; Ethylnitrosourea; Liver Neoplasms; Lomustine; Mammary Neoplasms, Experimental; Nitrosourea Compounds; Nucleic Acid Conformation

1986
Stability of solutions of antineoplastic agents during preparation and storage for in vitro assays. General considerations, the nitrosoureas and alkylating agents.
    Cancer chemotherapy and pharmacology, 1985, Volume: 14, Issue:2

    Topics: Alkylation; Antineoplastic Agents; Carmustine; Chlorambucil; Colony-Forming Units Assay; Cyclophosphamide; Drug Storage; Hydrogen-Ion Concentration; Lomustine; Mathematics; Melphalan; Nimustine; Nitrosourea Compounds; Solutions; Temperature; Tumor Stem Cell Assay

1985
[Chemotherapy of cancer of the large intestine].
    Sovetskaia meditsina, 1985, Issue:3

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Colonic Neoplasms; Drug Evaluation; Fluorouracil; Humans; Lomustine; Melphalan; Methotrexate; Rectal Neoplasms; Semustine; Vincristine

1985
High dose chemotherapy with autologous bone marrow rescue for high grade gliomas of the brain: a potential for improvement in therapeutic results.
    Neurosurgery, 1984, Volume: 15, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Brain Neoplasms; Carmustine; Combined Modality Therapy; Etoposide; Glioblastoma; Glioma; Humans; Lomustine; Teniposide

1984
Review: diagnosis of chemotherapy lung.
    AJR. American journal of roentgenology, 1981, Volume: 136, Issue:1

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Bleomycin; Busulfan; Carmustine; Cyclophosphamide; Female; Humans; Lomustine; Lung Diseases; Lung Neoplasms; Male; Mercaptopurine; Methotrexate; Middle Aged; Pulmonary Fibrosis; Radiography

1981
Chemotherapy in alimentary tract malignomas.
    Hepato-gastroenterology, 1981, Volume: 28, Issue:5

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Carmustine; Colonic Neoplasms; Cytarabine; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lomustine; Male; Methotrexate; Mitomycin; Mitomycins; Rectal Neoplasms; Semustine; Stomach Neoplasms; Streptozocin; Tegafur; Vincristine

1981
[Cancer chemotherapy with special reference to pharmacokinetics of nitrosoureas].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1982, Volume: 9, Issue:8

    Topics: Carmustine; Humans; Kinetics; Lomustine; Neoplasms; Nimustine; Nitrosourea Compounds; Semustine; Solubility; Streptozocin

1982
Chemotherapy of hormonally unresponsive prostatic carcinoma.
    The Urologic clinics of North America, 1984, Volume: 11, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Carmustine; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Diethylstilbestrol; Doxorubicin; Estramustine; Fluorouracil; Humans; Imidazoles; Lomustine; Male; Methotrexate; Mitomycin; Mitomycins; Prednimustine; Prednisone; Procarbazine; Prostatic Neoplasms; Random Allocation; Streptozocin; Vincristine

1984
Carcinogenic N-nitroso compounds and their environmental significance.
    Die Naturwissenschaften, 1984, Volume: 71, Issue:1

    Topics: Alkylation; Animals; Brain Neoplasms; Carcinogens; Carcinogens, Environmental; Carmustine; Dimethylnitrosamine; Dose-Response Relationship, Drug; Environmental Exposure; Food Analysis; Food Contamination; Humans; Hydroxylation; Leukemia; Life Style; Liver; Lomustine; Mice; Neoplasms; Nitrosamines; Nitroso Compounds; Rats; Risk; Smoking

1984
Treatment of neuroectodermal brain tumors.
    Annals of neurology, 1982, Volume: 12, Issue:3

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Astrocytoma; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Drug Therapy, Combination; Glioma; Humans; Lomustine; Middle Aged; Mitotic Index; Oligodendroglioma; Prospective Studies; Random Allocation; Semustine

1982
The nitrosoureas: carmustine (BCNU) and lomustine (CCNU).
    Cancer treatment reviews, 1982, Volume: 9, Issue:4

    Topics: Bone Marrow; Brain Neoplasms; Carmustine; Drug Therapy, Combination; Gastrointestinal Neoplasms; Hodgkin Disease; Humans; Kidney; Lomustine; Lung; Lung Neoplasms; Lymphoma; Melanoma; Multiple Myeloma; Neoplasms; Nitrosourea Compounds

1982
Potentiation of chemotherapy by hypoxic cell radiation sensitizers--a review.
    International journal of radiation oncology, biology, physics, 1982, Volume: 8, Issue:6

    Topics: Anaerobiosis; Animals; Antineoplastic Agents; Carmustine; Cyclophosphamide; Drug Synergism; Lomustine; Mice; Misonidazole; Neoplasms, Experimental; Radiation-Sensitizing Agents

1982
Pharmacokinetics of alkylating agents.
    Cancer surveys, 1993, Volume: 17

    Topics: Alkylating Agents; Carmustine; Chlorambucil; Cyclophosphamide; Humans; Ifosfamide; Lomustine; Melphalan; Neoplasms; Nitrosourea Compounds; Organophosphorus Compounds; Thiotepa

1993
Systemic chemotherapy in the treatment of malignant melanoma.
    Expert opinion on pharmacotherapy, 2003, Volume: 4, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carmustine; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Dacarbazine; Humans; Lomustine; Melanoma; Neoplasm Metastasis; Skin Neoplasms; Tamoxifen; Treatment Outcome; Vincristine

2003
[Clinical significance of mustoforan in management of malignant glioma].
    Voprosy onkologii, 2007, Volume: 53, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Astrocytoma; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Disease-Free Survival; Female; Glioblastoma; Glioma; Humans; Lomustine; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm, Residual; Nitrosourea Compounds; Oligodendroglioma; Organophosphorus Compounds; Semustine; Survival Analysis; Treatment Outcome

2007
What is the translational efficacy of chemotherapeutic drug research in neuro-oncology? A systematic review and meta-analysis of the efficacy of BCNU and CCNU in animal models of glioma.
    Journal of neuro-oncology, 2009, Volume: 91, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Disease Models, Animal; Drug Evaluation; Glioma; Humans; Lomustine; Meta-Analysis as Topic

2009
[Treatment of glioma with temozolomide].
    Brain and nerve = Shinkei kenkyu no shinpo, 2009, Volume: 61, Issue:7

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Dacarbazine; DNA Damage; Glioblastoma; Humans; Leukemia, Myeloid, Acute; Lomustine; Myelodysplastic Syndromes; Neoplasms, Second Primary; O(6)-Methylguanine-DNA Methyltransferase; Temozolomide

2009
High-dose etoposide in allogeneic stem cell transplantation.
    Cancer chemotherapy and pharmacology, 2012, Volume: 70, Issue:6

    Topics: Adenine Nucleotides; Anthracyclines; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Busulfan; Carboplatin; Carmustine; Clinical Trials as Topic; Clofarabine; Cyclophosphamide; Dose Fractionation, Radiation; Drug Administration Schedule; Etoposide; Humans; Ifosfamide; Leukemia; Leukemia, Myeloid, Acute; Lomustine; Mucositis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radiotherapy, Adjuvant; Severity of Illness Index; Stem Cell Transplantation; Transplantation Conditioning; Transplantation, Homologous; Whole-Body Irradiation

2012

Trials

32 trial(s) available for carmustine and lomustine

ArticleYear
Chemotherapy: adjuvant to surgery and radiation therapy.
    Seminars in oncology, 1975, Volume: 2, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Fluorouracil; Glioma; Humans; Lomustine; Maryland; Plicamycin; Prospective Studies; Semustine; Vincristine

1975
Nitrosourea combinations in lung cancer.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Adenocarcinoma; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Carmustine; Clinical Trials as Topic; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Humans; Lomustine; Lung Neoplasms; Methotrexate; Nitrosourea Compounds; Semustine

1976
Controlled study with BCNU vs. CCNU as adjuvant chemotherapy following surgery plus radiotherapy for glioblastoma multiforme.
    Cancer clinical trials, 1979,Spring, Volume: 2, Issue:1

    Topics: Brain Neoplasms; Carmustine; Clinical Trials as Topic; Female; Glioblastoma; Humans; Lomustine; Male; Middle Aged; Nitrosourea Compounds; Radiotherapy, High-Energy; Random Allocation

1979
Vincristine, prednisone and L-asparaginase in the induction of remission in children with acute lymphoblastic leukemia following relapse.
    Cancer, 1978, Volume: 41, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Agents; Asparaginase; Bone Marrow; Brain Neoplasms; Carmustine; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Female; Humans; Infant; Leukemia, Lymphoid; Lomustine; Male; Prednisone; Recurrence; Remission, Spontaneous; Vincristine

1978
Multidisciplinary treatment for central nervous system tumours with nitrosourea compounds.
    Acta neurochirurgica, 1978, Volume: 41, Issue:4

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Female; Humans; Lomustine; Male; Middle Aged; Neoplasm Metastasis; Nitrosourea Compounds

1978
DTIC (NSC-45388) in malignant melanoma: a perspective.
    Cancer treatment reports, 1976, Volume: 60, Issue:2

    Topics: Animals; Antineoplastic Agents; Carmustine; Clinical Trials as Topic; Dacarbazine; Drug Evaluation; Drug Therapy, Combination; Humans; Lomustine; Melanoma; Mice; Neoplasm Metastasis; Nitrosourea Compounds; Remission, Spontaneous; Triazenes

1976
Phase I evaluation of DTIC (NSC-45388) and other studies in malignant melanoma in the Central Oncology Group.
    Cancer treatment reports, 1976, Volume: 60, Issue:2

    Topics: Carmustine; Clinical Trials as Topic; Dacarbazine; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Leukopenia; Lomustine; Male; Melanoma; Middle Aged; Nausea; Sex Factors; Thrombocytopenia; Triazenes; Vincristine; Vomiting

1976
Eastern Cooperative Oncology Group studies with DTIC (NSC-45388).
    Cancer treatment reports, 1976, Volume: 60, Issue:2

    Topics: Adult; Aged; Carmustine; Clinical Trials as Topic; Dacarbazine; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Lomustine; Male; Melanoma; Middle Aged; Sex Factors; Skin Neoplasms; Triazenes

1976
Nitrosoureas in the management of disseminated malignant melanoma.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Carmustine; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, Combination; Humans; Lomustine; Melanoma; Nitrosourea Compounds; Semustine

1976
Nitrosoureas as single agents in the treatment of pulmonary cancer.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Carmustine; Clinical Trials as Topic; Cyclophosphamide; Female; Humans; Lomustine; Lung Neoplasms; Male; Nitrosourea Compounds; Semustine

1976
Southeastern Cancer Study Group trials with nitrosoureas in Hodgkin's disease.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Administration, Oral; Carmustine; Clinical Trials as Topic; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Hodgkin Disease; Humans; Lomustine; Nitrosourea Compounds; Prednisone; Procarbazine; Semustine; Vinblastine

1976
Nitrosoureas in multiple myeloma.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Carmustine; Clinical Trials as Topic; Doxorubicin; Drug Evaluation; Drug Therapy, Combination; Humans; Lomustine; Multiple Myeloma; Neoplasm Recurrence, Local; Nitrosourea Compounds; Prednisone; Remission, Spontaneous

1976
Adjuvant nitrosourea therapy for glioblastoma.
    Archives of neurology, 1976, Volume: 33, Issue:11

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Carmustine; Child; Child, Preschool; Drug Evaluation; Female; Glioma; Humans; Lomustine; Male; Middle Aged; Nitrosourea Compounds; Semustine

1976
DTIC (nsc-45388) and combination therapy for melanoma. I. Studies with DTIC, BCNU (NSC-409962), CCNU (NSC-79037), vincristine (NSC-67574), and hydroxyurea (NSC-32065).
    Cancer treatment reports, 1976, Volume: 60, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Carmustine; Dacarbazine; Drug Therapy, Combination; Humans; Hydroxyurea; Lomustine; Melanoma; Middle Aged; Triazenes; United States; Vincristine

1976
Superiority of post-radiotherapy adjuvant chemotherapy with CCNU, procarbazine, and vincristine (PCV) over BCNU for anaplastic gliomas: NCOG 6G61 final report.
    International journal of radiation oncology, biology, physics, 1990, Volume: 18, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Combined Modality Therapy; Glioblastoma; Glioma; Humans; Lomustine; Middle Aged; Multicenter Studies as Topic; Procarbazine; Prognosis; Randomized Controlled Trials as Topic; United States; Vincristine

1990
Phase III comparison of BCNU and the combination of procarbazine, CCNU, and vincristine administered after radiotherapy with hydroxyurea for malignant gliomas.
    Journal of neurosurgery, 1985, Volume: 63, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Clinical Trials as Topic; Combined Modality Therapy; Female; Glioblastoma; Glioma; Humans; Hydroxyurea; Lomustine; Male; Middle Aged; Procarbazine; Vincristine

1985
Vincristine and prednisone prolong the survival of patients receiving intravenous or oral melphalan for multiple myeloma: Cancer and Leukemia Group B experience.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1988, Volume: 6, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carmustine; Clinical Trials as Topic; Drug Administration Schedule; Female; Humans; Lomustine; Male; Melphalan; Middle Aged; Multiple Myeloma; Prednisone; Random Allocation; Vincristine

1988
Chemotherapy and combined modality therapy for Hodgkin's disease: a progress report on Cancer and Leukemia Group B studies.
    Cancer treatment reports, 1982, Volume: 66, Issue:4

    Topics: Adult; Antineoplastic Agents; Bleomycin; Carmustine; Doxorubicin; Drug Therapy, Combination; Female; Hodgkin Disease; Humans; Lomustine; Male; Prednisone; Procarbazine; Vincristine

1982
Chemotherapy of hormonally unresponsive prostatic carcinoma.
    The Urologic clinics of North America, 1984, Volume: 11, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Carmustine; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Diethylstilbestrol; Doxorubicin; Estramustine; Fluorouracil; Humans; Imidazoles; Lomustine; Male; Methotrexate; Mitomycin; Mitomycins; Prednimustine; Prednisone; Procarbazine; Prostatic Neoplasms; Random Allocation; Streptozocin; Vincristine

1984
Dimethyl triazeno imidazole carboxamide and combination therapy for melanoma. IV. Late results after complete response to chemotherapy (Central Oncology Group protocols 7130, 7131, and 7131A).
    Cancer, 1984, Mar-15, Volume: 53, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Clinical Trials as Topic; Dacarbazine; Female; Humans; Hydroxyurea; Lomustine; Male; Melanoma; Middle Aged; Neoplasm Recurrence, Local; Retrospective Studies; Sex Factors; Skin Neoplasms; Soft Tissue Neoplasms; Time Factors; Vincristine

1984
Treatment of neuroectodermal brain tumors.
    Annals of neurology, 1982, Volume: 12, Issue:3

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Astrocytoma; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Drug Therapy, Combination; Glioma; Humans; Lomustine; Middle Aged; Mitotic Index; Oligodendroglioma; Prospective Studies; Random Allocation; Semustine

1982
[Use of nitrosourea compounds in cancer chemotherapy].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1982, Sep-27, Volume: 37, Issue:36

    Topics: Carmustine; Clinical Trials as Topic; Humans; Lomustine; Neoplasms; Nitrosourea Compounds; Semustine

1982
The superiority of CCNU in the treatment of advanced Hodgkin's disease: Cancer and Leukemia Group B Study.
    Cancer, 1981, Jan-01, Volume: 47, Issue:1

    Topics: Adult; Carmustine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Hodgkin Disease; Humans; Leukopenia; Lomustine; Male; Nausea; Nitrosourea Compounds; Prognosis; Thrombocytopenia; Vomiting

1981
Primary intracranial gliomas: clinical studies and treatment regimens of the Brain Tumor Research Center, University of California, San Francisco, 1977-1979.
    Cancer treatment reports, 1981, Volume: 65 Suppl 2

    Topics: Antineoplastic Agents; Brain Neoplasms; California; Carmustine; Clinical Trials as Topic; Drug Therapy, Combination; Fluorouracil; Follow-Up Studies; Glioma; Humans; Hydroxyurea; Lomustine; Neoplasm Recurrence, Local; Procarbazine; Vincristine

1981
Comparison of oral melphalan, CCNU, and BCNU with and without vincristine and prednisone in the treatment of multiple myeloma. Cancer and Leukemia Group B experience.
    Cancer, 1982, Nov-01, Volume: 50, Issue:9

    Topics: Antineoplastic Agents; Carmustine; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leukopenia; Lomustine; Male; Melphalan; Middle Aged; Multiple Myeloma; Prednisone; Random Allocation; Thrombocytopenia; Vincristine

1982
Correlation of in vitro drug sensitivity testing results with response to chemotherapy and survival: comparison of non-small cell lung cancer and small cell lung cancer.
    Journal of cellular biochemistry. Supplement, 1996, Volume: 24

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Carmustine; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Etoposide; Evaluation Studies as Topic; Humans; Lomustine; Lung Neoplasms; Mechlorethamine; Methotrexate; Palliative Care; Predictive Value of Tests; Prospective Studies; Specimen Handling; Survival Analysis; Treatment Outcome; Tumor Cells, Cultured; Vincristine

1996
Efficacy and toxicity of a CCNU-containing high-dose chemotherapy regimen followed by autologous hematopoietic cell transplantation in relapsed or refractory Hodgkin's disease.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2001, Volume: 7, Issue:10

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Child; Cyclophosphamide; Dose-Response Relationship, Drug; Etoposide; Female; Hodgkin Disease; Humans; Lomustine; Lung Diseases, Interstitial; Lymphoma, Non-Hodgkin; Male; Maximum Tolerated Dose; Middle Aged; Salvage Therapy; Stem Cell Transplantation; Survival Rate; Therapeutic Equivalency; Transplantation, Autologous

2001
[Therapeutic effect on glioblastoma of chemotherapy on the basis of brain irradiation].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2001, Volume: 23, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Carmustine; Child; Dose-Response Relationship, Radiation; Female; Glioblastoma; Humans; Lomustine; Male; Middle Aged; Survival Analysis; Survival Rate; Treatment Outcome

2001
[Postoperative chemoradiotherapy for cerebral glioblastoma].
    Voprosy onkologii, 2008, Volume: 54, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Dose Fractionation, Radiation; Drug Administration Schedule; Female; Glioblastoma; Humans; Immunotherapy; Interleukin-2; Lomustine; Male; Middle Aged; Postoperative Period; Radiotherapy, Adjuvant; Recombinant Proteins; Survival Analysis; Treatment Outcome; Vincristine

2008
Impact of adjuvant chemotherapy for gliomatosis cerebri.
    BMC cancer, 2010, Aug-13, Volume: 10

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Child; Cohort Studies; Combined Modality Therapy; Cranial Irradiation; Dacarbazine; Female; Humans; Lomustine; Male; Middle Aged; Neoplasm Staging; Neoplasms, Neuroepithelial; Neoplasms, Radiation-Induced; Procarbazine; Prognosis; Retrospective Studies; Survival Rate; Temozolomide; Vincristine; Young Adult

2010
The role of temozolomide in the management of patients with newly diagnosed anaplastic astrocytoma: a comparison of survival in the era prior to and following the availability of temozolomide.
    Journal of neuro-oncology, 2016, Volume: 127, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustine; Dacarbazine; Female; Follow-Up Studies; Humans; Lomustine; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Procarbazine; Prognosis; Retrospective Studies; Survival Rate; Temozolomide; Vincristine

2016
LEAM versus CBV for conditioning in autologous hematopoietic stem cell transplantation for lymphoma.
    Bone marrow transplantation, 2019, Volume: 54, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cyclophosphamide; Doxorubicin; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Lomustine; Lymphoma; Male; Methotrexate; Prednisolone; Prospective Studies; Transplantation Conditioning; Transplantation, Autologous

2019

Other Studies

178 other study(ies) available for carmustine and lomustine

ArticleYear
Synthesis of analogues of N-(2-chloroethyl)-N'-(trans-4-methylcyclohexyl)-N-nitrosourea for evaluation as anticancer agents.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:2

    Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Isomerism; Leukemia L1210; Mice; Mice, Inbred Strains; Nitrosourea Compounds; Semustine; Structure-Activity Relationship

1977
Inhibition of solid tumors by nitrosoureas. 1. Lewis lung carcinoma.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:2

    Topics: Animals; Carcinoma; Leukemia L1210; Lung Neoplasms; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Nitrosourea Compounds; Structure-Activity Relationship; Time Factors

1977
An analysis of 1-(2-chloroethyl)-1-nitrosourea activity at the cellular level.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:11

    Topics: Animals; Antineoplastic Agents; Carmustine; Cell Survival; Drug Evaluation, Preclinical; Ethylnitrosourea; Leukemia L1210; Leukemia P388; Lomustine; Mice; Nitrosourea Compounds; Streptozocin; Structure-Activity Relationship

1983
Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:6

    Topics: Animals; Blood-Brain Barrier; Brain; Capillary Permeability; Male; Models, Biological; Molecular Weight; Rats; Rats, Inbred F344; Solubility; Structure-Activity Relationship

1980
Antitumor structure-activity relations. Nitrosoureas vs. L-1210 leukemia.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:10

    Topics: Animals; Antineoplastic Agents; Leukemia L1210; Mice; Models, Theoretical; Nitrosourea Compounds; Solubility; Structure-Activity Relationship

1980
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:4

    Topics: Antineoplastic Agents; Models, Chemical; Octanols; Quantitative Structure-Activity Relationship; Water

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
The sensitivity to cytotoxic agents of the EMT6 tumor in vivo. Comparative response of lung nodules in rapid expotential growth and of the solid flank tumour.
    British journal of cancer, 1976, Volume: 33, Issue:3

    Topics: Animals; Antineoplastic Agents; Bleomycin; Carmustine; Cell Line; Cell Survival; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Lomustine; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Time Factors

1976
[Chemotherapy in bronchogenic carcinoma (author's transl)].
    Rontgen-Blatter; Zeitschrift fur Rontgen-Technik und medizinisch-wissenschaftliche Photographie, 1977, Volume: 30, Issue:4

    Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Bronchogenic; Carmustine; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Humans; Lomustine; Lung Neoplasms; Mechlorethamine; Methotrexate; Procarbazine; Vinblastine

1977
Comparative chemosensitivity of exponential- versus plateau-phase cells in both in vitro model systems.
    Cancer treatment reports, 1976, Volume: 60, Issue:12

    Topics: Animals; Antineoplastic Agents; Bleomycin; Carmustine; Cell Division; Cell Survival; Cells, Cultured; Doxorubicin; Kinetics; Lomustine; Lung Neoplasms; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Time Factors

1976
Pharmacokinetic studies of a transplantable murine renal adenocarcinoma.
    Investigative urology, 1977, Volume: 15, Issue:1

    Topics: Adenocarcinoma; Animals; Bleomycin; Carmustine; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Evaluation, Preclinical; Kidney Neoplasms; Lomustine; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms, Experimental

1977
The cause of G2-arrest in Chinese hamster ovary cells treated with anticancer drugs.
    Journal of the National Cancer Institute, 1976, Volume: 57, Issue:5

    Topics: Animals; Antineoplastic Agents; Carmustine; Cell Division; Cell Fusion; Cells, Cultured; Chromosomes; Cricetinae; Cyclohexanecarboxylic Acids; DNA; Lomustine; Mitosis; Nitrogen Mustard Compounds; Teniposide; Zinostatin

1976
Cell proliferation kinetics and drug sensitivity of exponential and stationary populations of cultured L1210 cells.
    Cancer research, 1977, Volume: 37, Issue:4

    Topics: Amino Acids; Animals; Antineoplastic Agents; Carmustine; Cell Division; Cell Survival; Cells, Cultured; Culture Media; Cytarabine; Dactinomycin; Daunorubicin; DNA, Neoplasm; Doxorubicin; Glucose; Hydroxyurea; Kinetics; Leukemia L1210; Lomustine; Streptozocin; Thymidine; Vincristine

1977
A structure-activity analysis of chemical and biological parameters of chloroethylnitrosoureas in mice.
    Cancer research, 1977, Volume: 37, Issue:8 Pt 1

    Topics: Alkylation; Animals; Bone Marrow; Carmustine; Ethyl Chloride; Ethylnitrosourea; Half-Life; Leukemia L1210; Leukocyte Count; Lomustine; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Neutrophils; Nitrosourea Compounds; Statistics as Topic; Streptozocin; Structure-Activity Relationship

1977
Comparison of biochemical and biological effects of four nitrosoureas with differing carbamoylating activities.
    Cancer research, 1978, Volume: 38, Issue:8

    Topics: Animals; Carmustine; Cell Survival; Cells, Cultured; Chemical Phenomena; Chemistry; DNA, Neoplasm; Ethylnitrosourea; Leukemia L1210; Lomustine; Neoplasm Proteins; Nitrosourea Compounds; RNA, Neoplasm; Streptozocin; Time Factors

1978
DNA-protein cross-linking and DNA interstrand cross-linking by haloethylnitrosoureas in L1210 cells.
    Cancer research, 1978, Volume: 38, Issue:10

    Topics: Animals; Carmustine; Cells, Cultured; Chemical Phenomena; Chemistry; DNA, Neoplasm; Endopeptidases; Leukemia L1210; Lomustine; Mechlorethamine; Neoplasm Proteins; Nitrosourea Compounds; Streptozocin

1978
Measurements of DNA damage in Chinese hamster cells treated with equitoxic and equimutagenic doses of nitrosoureas.
    Cancer research, 1978, Volume: 38, Issue:10

    Topics: Carmustine; Cell Line; Cell Survival; Cyanates; DNA; Dose-Response Relationship, Drug; Ethyl Chloride; Lomustine; Methylnitrosourea; Mutation; Nitrosourea Compounds; Streptozocin; Time Factors

1978
Examination of four newly synthesized 2-chloroethylnitrosoureas in comparison with BCNU, CCNU, MeCCNU, chlorozotocin and hydroxyethyl-CNU in preterminal rat leukemia L 5222.
    Journal of cancer research and clinical oncology, 1979, Volume: 95, Issue:1

    Topics: Animals; Carmustine; Drug Evaluation, Preclinical; Female; Leukemia, Experimental; Lomustine; Male; Nitrosourea Compounds; Rats; Semustine; Streptozocin

1979
Clinical management of advanced gastrointestinal cancer.
    Cancer, 1975, Volume: 36, Issue:2

    Topics: Adenoma, Islet Cell; Carcinoma, Hepatocellular; Carmustine; Colonic Neoplasms; Cytarabine; Drug Therapy, Combination; Floxuridine; Fluorouracil; Gastrointestinal Neoplasms; Humans; Liver Neoplasms; Lomustine; Malignant Carcinoid Syndrome; Mitomycins; Pancreatic Neoplasms; Rectal Neoplasms; Stomach Neoplasms; Streptozocin

1975
Walter Hubert lecture Chemotherapy of upper gastrointestinal carcinoma.
    British journal of cancer, 1976, Volume: 34, Issue:3

    Topics: Adenoma, Islet Cell; Antineoplastic Agents; Carcinoid Tumor; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Carmustine; Colonic Neoplasms; Drug Therapy, Combination; Esophageal Neoplasms; Fluorouracil; Gastrointestinal Neoplasms; Humans; Liver Neoplasms; Lomustine; Malignant Carcinoid Syndrome; Nitrosourea Compounds; Pancreatic Neoplasms; Pyrimidines; Rectal Neoplasms; Stomach Neoplasms; Streptozocin

1976
Single-agent chemotherapy of brain tumors. A five-year review.
    Archives of neurology, 1976, Volume: 33, Issue:11

    Topics: Astrocytoma; Bone Marrow Diseases; Brain Neoplasms; Carmustine; Glioma; Humans; Imidazoles; Lomustine; Medulloblastoma; Melanoma; Nitrosourea Compounds; Peripheral Nervous System Diseases; Procarbazine; Time Factors; Vincristine

1976
Chemotherapeutic trials on human malignant astrocytomas in organ culture.
    Journal of neurosurgery, 1977, Volume: 46, Issue:3

    Topics: Antineoplastic Agents; Astrocytoma; Carmustine; Cell Survival; Cyanides; Drug Evaluation, Preclinical; Etoposide; Humans; Lomustine; Luciferases; Methylprednisolone; NAD; Organ Culture Techniques

1977
[Polychemotherapy of glioblastoma multiforme].
    Deutsche medizinische Wochenschrift (1946), 1977, Sep-09, Volume: 102, Issue:36

    Topics: Adult; Brain Neoplasms; Carmustine; Glioblastoma; Humans; Lomustine; Male

1977
Adjuvant chemotherapy with nitrosourea compounds following surgery plus radiotherapy in glioblastoma multiforme.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1978, Volume: 68

    Topics: Brain Neoplasms; Carmustine; Glioblastoma; Humans; Lomustine; Nitrosourea Compounds; Semustine

1978
[Value of chemotherapy associated with conventional treatment of malignant gliomas of the brain. Study of 95 cases with histological verification and follow-up of 1 to 6 years 9 months].
    Revue neurologique, 1979, Volume: 135, Issue:3

    Topics: Administration, Oral; Adult; Brain Neoplasms; Carmustine; Drug Evaluation; Drug Therapy, Combination; Female; Follow-Up Studies; Glioblastoma; Glioma; Humans; Injections, Intravenous; Lomustine; Male; Middle Aged; Nitrosourea Compounds; Podophyllotoxin; Retrospective Studies; Teniposide

1979
Mutagenicity of nitrosourea compounds for Salmonella typhimurium.
    Journal of the National Cancer Institute, 1978, Volume: 60, Issue:6

    Topics: Carmustine; Lomustine; Methods; Methylnitrosourea; Mutagens; Nitrosourea Compounds; Salmonella typhimurium; Semustine

1978
Clinical bone marrow transplantation (BMT) in children with acute lymphoblastic leukemia (ALL). Presentation of cases (Munchen group) [proceedings].
    Pathologie-biologie, 1978, Volume: 26, Issue:1

    Topics: Bone Marrow Transplantation; Carmustine; Child; Cyclophosphamide; Cytarabine; Female; Graft Survival; Humans; Leukemia, Lymphoid; Lomustine; Male; Transplantation, Homologous

1978
Combined effects of BCG or Candida albicans (CA) with antitumor agents against a virus-induced lymphoma in mice.
    European journal of cancer, 1979, Volume: 15, Issue:11

    Topics: Adjuvants, Immunologic; Animals; Antineoplastic Agents; BCG Vaccine; Candida albicans; Carmustine; Drug Synergism; Drug Therapy, Combination; Female; Leukemia, Experimental; Lomustine; Lymphoma; Male; Mice; Mice, Inbred BALB C; Moloney murine leukemia virus; Nitrosourea Compounds

1979
Treatment of primitive malignant tumors of the central nervous system. Clinical evaluation of 91 cases.
    Acta neurologica, 1979, Volume: 1, Issue:1

    Topics: Astrocytoma; Brain Neoplasms; Carmustine; Ependymoma; Glioma; Humans; Lomustine; Oligodendroglioma

1979
Response of exponentially growing, stationary-phase, and synchronized cultured human colon carcinoma cells to treatment with nitrosourea derivatives.
    Cancer research, 1979, Volume: 39, Issue:7 Pt 1

    Topics: Carmustine; Cell Cycle; Cell Division; Cell Survival; Cells, Cultured; Colonic Neoplasms; Dose-Response Relationship, Drug; Humans; Interphase; Lomustine; Nitrosourea Compounds

1979
Design and evaluation of combination chemotherapy trials in experimental animal tumor systems.
    Cancer treatment reports, 1979, Volume: 63, Issue:5

    Topics: Animals; Antineoplastic Agents; Carmustine; Cisplatin; Colonic Neoplasms; Drug Evaluation, Preclinical; Drug Therapy, Combination; Evaluation Studies as Topic; Fluorouracil; Lomustine; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Neoplasms, Experimental; Research Design; Semustine

1979
Reactions of 1,3-bis(2-chloroethyl)-1-nitrosourea and 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea in aqueous solution.
    Journal of medicinal chemistry, 1979, Volume: 22, Issue:10

    Topics: Carmustine; Chemical Phenomena; Chemistry; Lomustine; Nitrosourea Compounds; Solutions; Water

1979
Comparison of the CCNU and BCNU modification of the in vitro radiation response in 9L brain tumor cells of rats.
    International journal of radiation oncology, biology, physics, 1979, Volume: 5, Issue:9

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Lomustine; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Time Factors

1979
Mechanism of uptake of nitrosoureas by L5178Y lymphoblasts in vitro.
    Cancer research, 1977, Volume: 37, Issue:4

    Topics: Animals; Biological Transport; Carmustine; Cell Membrane; Cells, Cultured; Cyanates; Cytosol; Kinetics; Leukemia, Experimental; Lomustine; Nitrosourea Compounds; Sodium

1977
DNA damage and repair in mouse leukemia L1210 cells treated with nitrogen mustard, 1,3-bis(2-chloroethyl)-1-nitrosourea, and other nitrosoureas.
    Cancer research, 1977, Volume: 37, Issue:7 Pt 1

    Topics: Animals; Carmustine; Cell Survival; Cells, Cultured; Chemical Phenomena; Chemistry; DNA Repair; DNA, Neoplasm; DNA, Single-Stranded; Leukemia L1210; Lomustine; Mechlorethamine; Methylnitrosourea; Neoplasm Proteins; Nitrosourea Compounds

1977
Desmosterol: a biochemical marker of glioma growth.
    Surgical neurology, 1977, Volume: 8, Issue:6

    Topics: Astrocytoma; Brain Neoplasms; Carmustine; Cholesterol; Chromatography, Gas; Desmosterol; Diagnosis, Differential; Ependymoma; Glioma; Humans; Lomustine; Medulloblastoma; Oligodendroglioma; Triparanol

1977
Paraneoplastic syndrome in childhood.
    Acta paediatrica Academiae Scientiarum Hungaricae, 1977, Volume: 18, Issue:1

    Topics: Brain Diseases; Carmustine; Child, Preschool; Humans; Lomustine; Male; Mediastinal Neoplasms; Methotrexate; Neuroblastoma; Syndrome

1977
Chemotherapy of human nervous system tumors: influence on cerebrospinal fluid sterols.
    National Cancer Institute monograph, 1977, Volume: 46

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Carmustine; Cholesterol; Desmosterol; Female; Humans; Lomustine; Male; Middle Aged

1977
The contemporary role of chemotherapy in the treatment of malignant brain tumor.
    Clinical neurosurgery, 1978, Volume: 25

    Topics: Adrenal Cortex Hormones; Animals; Brain Neoplasms; Carmustine; Dose-Response Relationship, Drug; Drug Evaluation; Glioma; Humans; Inactivation, Metabolic; Lomustine; Neoplasms, Experimental; Prognosis; Radiotherapy Dosage; Semustine

1978
Rationale of chemotherapeutic adjuvant treatment.
    Archiv fur Geschwulstforschung, 1978, Volume: 48, Issue:7

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Carmustine; Cyclophosphamide; Drug Administration Schedule; Fluorouracil; Humans; Leukemia L1210; Lomustine; Mercaptopurine; Methotrexate; Mice; Neoplasms

1978
Visual abnormalities following nitrosourea treatment.
    Medical and pediatric oncology, 1978, Volume: 5, Issue:1

    Topics: Carmustine; Humans; Lomustine; Nitrosourea Compounds; Retina; Semustine; Vision Disorders; Visual Acuity

1978
Correlations between experimental chemotherapy in the murine glioma and effectiveness of clinical therapy regimens.
    Cancer chemotherapy and pharmacology, 1978, Volume: 1, Issue:1

    Topics: Animals; Carmustine; Dianhydrogalactitol; Drug Therapy, Combination; Ellipticines; Glioma; Lomustine; Male; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neoplasms, Experimental; Procarbazine; Time Factors; Transplantation, Homologous

1978
Relationship of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) and 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) pharmacokinetics of uptake, distribution, and tissue/plasma partitioning in rat organs and intracerebral tumors.
    Cancer chemotherapy and pharmacology, 1978, Volume: 1, Issue:4

    Topics: Animals; Brain Neoplasms; Carmustine; DNA; Kinetics; Lomustine; Male; Neoplasm Proteins; Nitrosourea Compounds; Protein Binding; Rats; Rats, Inbred F344; RNA; Tissue Distribution

1978
The effect of phenobarbital pretreatment on the antitumor activity of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU), 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) and 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidyl-1-nitrosourea (PCNU), and on the plasma p
    The Journal of pharmacology and experimental therapeutics, 1979, Volume: 208, Issue:1

    Topics: Alkylating Agents; Animals; Biotransformation; Brain Neoplasms; Carmustine; Dexamethasone; Drug Interactions; In Vitro Techniques; Kinetics; Liver; Lomustine; Male; Methylprednisolone; Neoplasms, Experimental; Nitrosourea Compounds; Phenobarbital; Phenytoin; Rats; Rats, Inbred F344

1979
Multimodal surgical adjuvant therapy for a broad spectrum of tumors in humans.?
    Surgery, gynecology & obstetrics, 1976, Volume: 142, Issue:6

    Topics: Adult; Altretamine; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Carmustine; Colonic Neoplasms; Cyclophosphamide; Dacarbazine; Doxorubicin; Drug Evaluation; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Lomustine; Lung Neoplasms; Male; Melanoma; Mitolactol; Neoplasms; Osteosarcoma; Pancreatic Neoplasms; Rectal Neoplasms; Vincristine

1976
Pharmacology of the nitrosoureas: an overview.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Animals; Carmustine; Dogs; Half-Life; Haplorhini; Humans; Lomustine; Mice; Microsomes, Liver; Nitrosourea Compounds; Semustine

1976
Interstrand cross-linking of DNA by 1,3-bis(2-chloroethyl)-1-nitrosourea and other 1-(2-haloethyl)-1-nitrosoureas.
    Cancer research, 1977, Volume: 37, Issue:5

    Topics: Carmustine; Chemical Phenomena; Chemistry; DNA; Kinetics; Lomustine; Methylnitrosourea; Nitrosourea Compounds

1977
Single drug and combination chemotherapy in the treatment. Disseminated malignant melanoma.
    Minnesota medicine, 1977, Volume: 60, Issue:8

    Topics: Antineoplastic Agents; Carmustine; Dacarbazine; Drug Therapy, Combination; Humans; Hydroxyurea; Lomustine; Melanoma; Neoplasm Metastasis; Skin Neoplasms; Vincristine

1977
Chemotherapy of brain tumors.
    Advances in neurology, 1976, Volume: 15

    Topics: Brain Neoplasms; Carmustine; Drug Combinations; Glioma; Humans; Lomustine; Methotrexate; Podophyllotoxin; Vincristine

1976
A chemical basis for the antitumor activity of chloroethylnitrosoureas.
    Biochemical pharmacology, 1976, Mar-15, Volume: 25, Issue:6

    Topics: Animals; Antineoplastic Agents; Buffers; Carmustine; Chemical Phenomena; Chemistry; Ethylnitrosourea; Ions; Leukemia L1210; Lomustine; Nitrosourea Compounds; Solutions; Time Factors

1976
Gastrointestinal cancer. Treatment with fluorouracil-nitrosourea combinations.
    JAMA, 1976, May-10, Volume: 235, Issue:19

    Topics: Carmustine; Colonic Neoplasms; Drug Therapy, Combination; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Liver Neoplasms; Lomustine; Male; Methods; Nitrosourea Compounds; Pancreatic Neoplasms; Rectal Neoplasms; Remission, Spontaneous; Semustine; Stomach Neoplasms

1976
The nitrosoureas: an outline of clinical schedules and toxic effects.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Administration, Oral; Bone Marrow; Capsules; Carmustine; Humans; Injections, Intravenous; Lomustine; Nausea; Nitrosourea Compounds; Semustine

1976
Nitrosourea chemotherapy for primary malignant gliomas.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Brain Neoplasms; Carmustine; Drug Therapy, Combination; Fluorouracil; Glioma; Humans; Lomustine; Neoplasm Recurrence, Local; Nitrosourea Compounds; Procarbazine; Semustine; Vincristine

1976
Nitrosourea pharmacodynamics in relation to the central nervous system.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Glioma; Humans; Lomustine; Mice; Molecular Weight; Neoplasms, Experimental; Nitrosourea Compounds; Semustine; Solubility

1976
Clinical studies with nitrosoureas in various solid tumors.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Adenocarcinoma; Breast Neoplasms; Carcinoma, Squamous Cell; Carmustine; Female; Genital Neoplasms, Female; Head and Neck Neoplasms; Humans; Kidney Neoplasms; Lomustine; Male; Neoplasms; Nitrosourea Compounds; Sarcoma; Semustine; Testicular Neoplasms

1976
Sterols in cerebrospinal fluid during nitrosourea chemotherapy of human brain tumors.
    Pharmacological research communications, 1976, Volume: 8, Issue:2

    Topics: Adult; Astrocytoma; Brain Neoplasms; Carmustine; Cholesterol; Desmosterol; Female; Glioma; Humans; Infant; Lomustine; Male; Middle Aged; Nitrosourea Compounds; Oligodendroglioma

1976
Effects of nitrosoureas on human DNA polymerase activities from acute and chronic granulocytic leukemia cells.
    Biochimica et biophysica acta, 1976, Apr-02, Volume: 425, Issue:4

    Topics: Acute Disease; Carmustine; Chronic Disease; DNA Nucleotidyltransferases; Granulocytes; Humans; Kinetics; Leukemia, Myeloid; Leukocytes; Lomustine; Nitrosourea Compounds; Templates, Genetic

1976
Decomposition of N-(2-chloroethyl)-N-nitrosoureas in aqueous media.
    Journal of medicinal chemistry, 1975, Volume: 18, Issue:6

    Topics: Carmustine; Chemical Phenomena; Chemistry; Chromatography, Gas; Lomustine; Mass Spectrometry; Nitrogen Mustard Compounds; Nitrosourea Compounds; Water

1975
Changes in sensitivity to cytotoxic agents occurring during the life history of monolayer cultures of a mouse tumour cell line.
    British journal of cancer, 1975, Volume: 31, Issue:4

    Topics: Alkylating Agents; Animals; Antibiotics, Antineoplastic; Carmustine; Cell Division; Cell Line; Cell Survival; Dactinomycin; Dose-Response Relationship, Drug; Doxorubicin; Lomustine; Mechlorethamine; Mice; Neoplasms, Experimental

1975
Treatment of mycosis fungoides with topical nitrosourea compounds: Further studies.
    Archives of dermatology, 1975, Volume: 111, Issue:12

    Topics: Administration, Topical; Adult; Aged; Bone Marrow; Carmustine; Cross Reactions; Drug Hypersensitivity; Female; Humans; Lomustine; Male; Mechlorethamine; Methylnitrosourea; Middle Aged; Mycosis Fungoides; Nitrosourea Compounds; Skin Neoplasms

1975
Editorial: Large-bowel cancer-The current status of treatment.
    Journal of the National Cancer Institute, 1976, Volume: 56, Issue:1

    Topics: Adjuvants, Immunologic; BCG Vaccine; Carmustine; Colonic Neoplasms; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Immunotherapy; Lomustine; Mitomycins; Neoplasm Metastasis; Neoplasm Recurrence, Local; Rectal Neoplasms; Semustine; United States

1976
A comparison of the lethal effects of three nitrosourea derivatives on cultured human lymphoma cells.
    Cancer research, 1976, Volume: 36, Issue:2 Pt 1

    Topics: Amphotericin B; Carmustine; Cell Line; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Lomustine; Lymphoma; Neoplasms, Experimental; Nitrosourea Compounds; Semustine; Time Factors; Vitamin A

1976
Nitrosoureas: important new drugs for the treatment of cancer.
    Arizona medicine, 1976, Volume: 33, Issue:2

    Topics: Carmustine; Humans; Lomustine; Neoplasms; Nitrosourea Compounds

1976
Chemotherapy for colorectal carcinoma.
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:8 Suppl

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carmustine; Chemotherapy, Adjuvant; Colorectal Neoplasms; Drug Administration Schedule; Fluorouracil; Humans; Lomustine; Mitomycin; Tegafur

1992
Effect of O6-benzylguanine analogues on sensitivity of human tumor cells to the cytotoxic effects of alkylating agents.
    Cancer research, 1991, Jul-01, Volume: 51, Issue:13

    Topics: Alkylating Agents; Antineoplastic Agents; Carmustine; Cell Survival; Cisplatin; Cyclophosphamide; DNA; DNA Damage; Drug Synergism; Guanine; Humans; In Vitro Techniques; Lomustine; Mesylates; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Streptozocin; Tumor Cells, Cultured

1991
New approaches to the chemotherapy of melanoma.
    Oncology (Williston Park, N.Y.), 1991, Volume: 5, Issue:5

    Topics: Alkaloids; Amifostine; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow Transplantation; Carmustine; Cisplatin; Cyclophosphamide; Dacarbazine; Daunorubicin; Humans; Lomustine; Melanoma; Nitrosourea Compounds; Paclitaxel; Procarbazine; Tamoxifen; Taurine; Thiotepa; Vincristine; Vindesine

1991
Effect of O6-benzylguanine on the sensitivity of human tumor xenografts to 1,3-bis(2-chloroethyl)-1-nitrosourea and on DNA interstrand cross-link formation.
    Cancer research, 1992, Mar-01, Volume: 52, Issue:5

    Topics: Animals; Carmustine; Colonic Neoplasms; DNA; DNA, Neoplasm; DNA, Single-Stranded; Drug Resistance; Drug Screening Assays, Antitumor; Drug Synergism; Female; Guanine; Humans; Lomustine; Mice; Mice, Nude; Transplantation, Heterologous; Tumor Cells, Cultured

1992
Nitrosoureas lomustine, carmustine and fotemustine induced hepatotoxic perturbations in rats: biochemical, morphological and flow cytometry studies.
    European journal of cancer (Oxford, England : 1990), 1991, Volume: 27, Issue:5

    Topics: Alkaline Phosphatase; Animals; Bilirubin; Carmustine; Cell Cycle; DNA; Dose-Response Relationship, Drug; Flow Cytometry; Liver; Lomustine; Nitrosourea Compounds; Organophosphorus Compounds; Rats; Transaminases

1991
2-Nitroimidazole potentiation of nitrosourea induced cytotoxicity in subcutaneous implants of rat 9L brain tumor cells.
    Journal of neuro-oncology, 1991, Volume: 11, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cell Line; Cell Survival; Drug Synergism; Etanidazole; Lomustine; Male; Misonidazole; Nitroimidazoles; Rats; Rats, Inbred F344; Streptozocin; Tumor Stem Cell Assay

1991
Thyroid function after treatment of brain tumors in children.
    The Journal of pediatrics, 1991, Volume: 119, Issue:5

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustine; Child; Child, Preschool; Cohort Studies; Combined Modality Therapy; Cranial Irradiation; Female; Glioma; Humans; Infant; Life Tables; Lomustine; Male; Procarbazine; Radiotherapy Dosage; Regression Analysis; Spinal Cord; Thyroid Diseases; Thyroid Gland; Thyrotropin; Thyroxine; Vincristine

1991
Chemosensitization of the nitrosoureas by 2-nitroimidazoles in the subcutaneous 9L tumor model: pharmacokinetic and structure-activity considerations.
    International journal of radiation oncology, biology, physics, 1990, Volume: 18, Issue:5

    Topics: Animals; Carmustine; Drug Synergism; Etanidazole; Lomustine; Male; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Nitrosourea Compounds; Rats; Rats, Inbred F344; Structure-Activity Relationship

1990
Cisplatin and CCNU synergism in spheroid cell subpopulations.
    British journal of cancer, 1990, Volume: 62, Issue:6

    Topics: Animals; Carmustine; Cell Hypoxia; Cell Line; Cell Survival; Cisplatin; Cricetinae; Dose-Response Relationship, Drug; Drug Synergism; Lomustine

1990
The VM model of glioma: preparation of multicellular tumour spheroids (MTS) and their response to chemotherapy.
    Journal of neuro-oncology, 1990, Volume: 9, Issue:2

    Topics: Animals; Carmustine; Cell Division; Disease Models, Animal; Drug Screening Assays, Antitumor; Glioma; Lomustine; Mice; Procarbazine; Tumor Cells, Cultured; Vincristine

1990
The chemotherapeutic response of a murine (VM) model of human glioma.
    British journal of cancer, 1990, Volume: 61, Issue:1

    Topics: Animals; Astrocytoma; Brain Neoplasms; Carmustine; Disease Models, Animal; Lomustine; Mice; Mice, Inbred Strains; Procarbazine; Skin Neoplasms; Vincristine

1990
In vitro chemosensitivity testing of Fotemustine (S 10036), a new antitumor nitrosourea.
    Cancer chemotherapy and pharmacology, 1990, Volume: 25, Issue:5

    Topics: Antineoplastic Agents; Carmustine; Cell Division; Cisplatin; Dacarbazine; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Lomustine; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds; Thymidine; Tumor Cells, Cultured

1990
Lysis of human promyelocytic HL-60 cells by amphotericin B in combination with 2-chloroethyl-1-nitrosoureas: role of the carbamoylating activity of nitrosoureas.
    Cancer research, 1990, Jun-01, Volume: 50, Issue:11

    Topics: Amphotericin B; Carmustine; Cell Line; Drug Therapy, Combination; Glutathione; Humans; L-Lactate Dehydrogenase; Leukemia, Promyelocytic, Acute; Lomustine; Nitrosourea Compounds

1990
Chemotherapy for malignant gliomas of the brain: a review of ten-years experience.
    Acta neurochirurgica, 1990, Volume: 103, Issue:1-2

    Topics: Antineoplastic Agents; Aziridines; Benzoquinones; Brain Neoplasms; Carmustine; Cyclohexenes; Glioma; Humans; Lomustine

1990
Base sequence specificity of three 2-chloroethylnitrosoureas.
    Biochemical pharmacology, 1990, Sep-15, Volume: 40, Issue:6

    Topics: Alkylation; Base Sequence; Carmustine; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; DNA; Guanine; Lomustine; Nitrosourea Compounds; Semustine; Structure-Activity Relationship

1990
Response of cultured human cell lines from rhabdomyosarcoma xenografts to treatment with chloroethylnitrosoureas.
    Cancer research, 1989, Feb-15, Volume: 49, Issue:4

    Topics: Animals; Antineoplastic Agents; Carmustine; Cell Division; Cell Survival; Drug Screening Assays, Antitumor; Humans; Kinetics; Lomustine; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Rhabdomyosarcoma; Streptozocin; Transplantation, Heterologous; Tumor Cells, Cultured

1989
Modulation of human lymphocyte O6-alkylguanine-DNA alkyltransferase by streptozotocin in vivo.
    Cancer research, 1989, Jun-01, Volume: 49, Issue:11

    Topics: Carmustine; Cisplatin; DNA Repair; DNA, Neoplasm; Drug Resistance; Humans; Lomustine; Lymphocytes; Methyltransferases; Neoplasms; O(6)-Methylguanine-DNA Methyltransferase; Streptozocin

1989
Ovarian function following chemotherapy for childhood brain tumours.
    Medical and pediatric oncology, 1989, Volume: 17, Issue:2

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Child; Child, Preschool; Female; Humans; Lomustine; Menarche; Ovary; Procarbazine; Puberty

1989
Expression of mammalian O6-alkylguanine-DNA alkyltransferase in a cell line sensitive to alkylating agents.
    Carcinogenesis, 1989, Volume: 10, Issue:9

    Topics: Alkylating Agents; Animals; Carmustine; Cell Division; Cell Line; Cricetinae; Cricetulus; Female; Guanine; Kinetics; Lomustine; Methylnitronitrosoguanidine; Methylnitrosourea; Methyltransferases; Mitoguazone; O(6)-Methylguanine-DNA Methyltransferase; Ovary; Transfection

1989
Glutathione and related enzymes in rat brain tumor cell resistance to 1,3-bis(2-chloroethyl)-1-nitrosourea and nitrogen mustard.
    Cancer research, 1987, May-15, Volume: 47, Issue:10

    Topics: Animals; Brain Neoplasms; Buthionine Sulfoximine; Carmustine; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Clone Cells; Dinitrochlorobenzene; Drug Resistance; gamma-Glutamyltransferase; Glioma; Glutathione; Glutathione Transferase; Lomustine; Mechlorethamine; Methionine Sulfoximine; Rats; Semustine

1987
Inhibition of intracellular esterases by antitumour chloroethylnitrosoureas. Measurement by flow cytometry and correlation with molecular carbamoylation activity.
    Biochemical pharmacology, 1988, Oct-15, Volume: 37, Issue:20

    Topics: Animals; Antineoplastic Agents; Carmustine; Esterases; Ethylnitrosourea; Flow Cytometry; Lomustine; Mice; Proteins; Spectrometry, Fluorescence; Streptozocin; Structure-Activity Relationship

1988
Effect of nitrosoureas on calmodulin activity in vitro and in mouse intestine in vivo.
    Cancer chemotherapy and pharmacology, 1985, Volume: 14, Issue:2

    Topics: Animals; Calcium; Calmodulin; Carmustine; Cattle; Cyanates; Cyclic AMP; Intestinal Mucosa; Intestines; Lomustine; Male; Mice; Nitrosourea Compounds; Phosphoric Diester Hydrolases; Semustine; Streptozocin

1985
Supraophthalmic carotid infusion for recurrent glioma: rationale, technique, and preliminary results for cisplatin and BCNU.
    Journal of neuro-oncology, 1985, Volume: 3, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustine; Carotid Artery, Internal; Cisplatin; Glioblastoma; Glioma; Humans; Infusions, Intra-Arterial; Lomustine; Middle Aged; Prognosis; Tomography, X-Ray Computed

1985
In vitro analysis of BCNU-sensitivity in human malignant gliomas. II. Cross-resistance studies with cisplatinum and nitrosoureas.
    Acta neurologica Scandinavica, 1986, Volume: 73, Issue:1

    Topics: Brain Neoplasms; Carmustine; Cells, Cultured; Cisplatin; Drug Resistance; Glioblastoma; Humans; Lomustine; Tumor Stem Cell Assay

1986
Effect of Fluosol-DA/O2 on tumor-cell and bone-marrow cytotoxicity of nitrosoureas in mice bearing FSA-II fibrosarcoma.
    International journal of cancer, 1986, Aug-15, Volume: 38, Issue:2

    Topics: Animals; Bone Marrow; Carbon Dioxide; Carmustine; Cell Survival; Drug Combinations; Fibrosarcoma; Fluorocarbons; Hydroxyethyl Starch Derivatives; Lomustine; Male; Mice; Mice, Inbred C3H; Nitrosourea Compounds; Oxygen; Semustine

1986
Medulloblastoma at the joint center for radiation therapy between 1968 and 1984. The influence of radiation dose on the patterns of failure and survival.
    Cancer, 1988, May-15, Volume: 61, Issue:10

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cerebellar Neoplasms; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Evaluation Studies as Topic; Female; Humans; Infant; Lomustine; Male; Medulloblastoma; Neoplasm Recurrence, Local; Particle Accelerators; Radiotherapy Dosage; Radiotherapy, High-Energy; Spinal Neoplasms; Vincristine

1988
Testicular damage after chemotherapy for childhood brain tumors.
    The Journal of pediatrics, 1988, Volume: 112, Issue:6

    Topics: Adolescent; Adult; Brain Neoplasms; Carmustine; Child; Follicle Stimulating Hormone; Follow-Up Studies; Humans; Lomustine; Luteinizing Hormone; Male; Testis; Testosterone

1988
Chemical specificity for induction of stress response genes by DNA-damaging drugs in human adenocarcinoma cells.
    Carcinogenesis, 1988, Volume: 9, Issue:10

    Topics: Adenocarcinoma; Antineoplastic Agents; Carmustine; Cell Line; Colonic Neoplasms; DNA Damage; Genes; Heat-Shock Proteins; Humans; Kinetics; Lomustine

1988
Capillary gas chromatography and thermionic N-P-specific detection of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) or 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) in stability and pharmacokinetic studies.
    Pharmaceutical research, 1988, Volume: 5, Issue:4

    Topics: Animals; Calibration; Carmustine; Chromatography, Gas; Drug Stability; Lomustine; Rabbits; Reproducibility of Results

1988
Interference with effects of amphotericin B on Candida albicans cells by 2-chloroethyl-1-nitrosoureas.
    Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:3

    Topics: Amphotericin B; Candida albicans; Carmustine; Catalase; Cyanates; Drug Interactions; Lomustine

1988
Nitrosoureido nucleosides as potential inhibitors of nucleotide biosynthesis.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:1

    Topics: Animals; Carmustine; Cell Division; DNA Replication; Drug Stability; Indicators and Reagents; Leukemia L1210; Lomustine; Mice; Neoplasm Proteins; Nitrosourea Compounds; Nucleosides; Nucleotides; Structure-Activity Relationship; Transcription, Genetic

1988
Successful chemotherapy for recurrent malignant oligodendroglioma.
    Annals of neurology, 1988, Volume: 23, Issue:4

    Topics: Adult; Antineoplastic Agents; Aziridines; Benzoquinones; Brain Neoplasms; Carmustine; Female; Humans; Lomustine; Male; Middle Aged; Oligodendroglioma; Procarbazine; Vincristine

1988
[Synthesis of antitumor nitrosourea derivatives and chemical studies of their mechanism of action].
    Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences, 1986, Issue:104

    Topics: Antineoplastic Agents; Bone Marrow; Carmustine; Humans; Lomustine; Nimustine; Nitroso Compounds; Nitrosourea Compounds

1986
Nature and biological significance of DNA modification by the haloethylnitrosoureas.
    IARC scientific publications, 1986, Issue:78

    Topics: Antineoplastic Agents; Carmustine; Chromatography, High Pressure Liquid; Cross-Linking Reagents; DNA; DNA Damage; DNA Repair; Ethylnitrosourea; Lomustine; Nitrosourea Compounds; Spectrophotometry, Ultraviolet; Structure-Activity Relationship

1986
Appraisal of blood vessels in the rat brain following administration of nitrosourea derivatives.
    Neuropatologia polska, 1986, Volume: 24, Issue:4

    Topics: Animals; Brain; Capillary Permeability; Carmustine; Female; Lomustine; Male; Rats; Rats, Inbred Strains

1986
Effect of cell cycle position on the survival of 9L cells treated with nitrosoureas that alkylate, cross-link, and carbamoylate.
    Cancer research, 1986, Volume: 46, Issue:5

    Topics: Alkylating Agents; Animals; Brain Neoplasms; Carbamates; Carmustine; Cell Cycle; Cell Line; Cell Survival; Cross-Linking Reagents; Ethylnitrosourea; Lomustine; Nitroso Compounds; Nitrosourea Compounds; Rats; Structure-Activity Relationship

1986
Effects of sodium cyanate in mice bearing B16 melanoma.
    Cancer chemotherapy and pharmacology, 1986, Volume: 17, Issue:3

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Carmustine; Cyanates; Eating; Female; Lomustine; Melanoma; Mice; Mice, Inbred C57BL; Thymidine

1986
Carcinogenesis in F-344 rats induced by nitrosohydroxyalkyl-chloroethylureas.
    Journal of cancer research and clinical oncology, 1986, Volume: 112, Issue:3

    Topics: Animals; Carmustine; Ethylnitrosourea; Female; Lomustine; Magnetic Resonance Spectroscopy; Male; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Rats, Inbred F344; Rats, Inbred Strains

1986
Effect of inhibition of glutathione reductase by carmustine on central nervous system oxygen toxicity.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 240, Issue:1

    Topics: Animals; Carmustine; Glucosephosphate Dehydrogenase; Glutathione Reductase; Lomustine; Male; Nitrosourea Compounds; Oxygen; Rats; Rats, Inbred Strains; Seizures; Superoxide Dismutase; Time Factors

1987
Sequential treatment with interferon and chemotherapy of metastatic malignant melanoma. Total remission of cutaneous and visceral metastasis, but not of cerebral metastasis.
    Tumori, 1987, Feb-28, Volume: 73, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Brain Neoplasms; Carmustine; Combined Modality Therapy; Dacarbazine; Drug Evaluation; Female; Humans; Interferon Type I; Lomustine; Lymphatic Metastasis; Male; Melanoma; Middle Aged; Recombinant Proteins; Skin Neoplasms; Vincristine

1987
Sensitization of cancer chemotherapeutic agents by nitroheterocyclics.
    Biochemical pharmacology, 1986, Jan-01, Volume: 35, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cell Survival; Drug Synergism; Heterocyclic Compounds; Hydroxamic Acids; Hypoxia; Lomustine; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents

1986
Emergence of nitrosourea resistant sublines of Lewis lung tumour following MeCCNU treatment in vivo.
    British journal of cancer, 1986, Volume: 53, Issue:2

    Topics: Animals; Carmustine; Cell Line; Cell Survival; Cisplatin; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Resistance; Lomustine; Lung Neoplasms; Melphalan; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Nitrosourea Compounds; Semustine; Time Factors

1986
Thermochemotherapy with cis-platinum, CCNU, BCNU, chlorambucil and melphalan on murine marrow and two tumours: therapeutic gain for melphalan only.
    The British journal of radiology, 1985, Volume: 58, Issue:685

    Topics: Animals; Antineoplastic Agents; Bone Marrow; Carmustine; Chlorambucil; Cisplatin; Combined Modality Therapy; Dose-Response Relationship, Drug; Female; Hyperthermia, Induced; Lomustine; Melphalan; Mice; Mice, Inbred C3H; Neoplasms, Experimental

1985
DNA polymerases in normal and regenerating rat liver and hepatomas: targets for chemotherapy.
    Advances in enzyme regulation, 1974, Volume: 12

    Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Carmustine; Cell Fractionation; Cyanates; DNA; DNA Nucleotidyltransferases; DNA, Neoplasm; Enzyme Activation; Liver; Liver Neoplasms; Liver Regeneration; Lomustine; Male; Membranes; Nitrosourea Compounds; Rats; Ribonucleotide Reductases; Thymidine Kinase; Thymidylate Synthase

1974
Sequential administration of two oncostatic drugs: study of modalities for pharmacodynamic potentiation.
    Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1974, Dec-10, Volume: 21, Issue:12

    Topics: Animals; Antineoplastic Agents; Carmustine; Cyclophosphamide; Cytarabine; Dactinomycin; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Kinetics; Leukemia L1210; Lomustine; Mathematics; Methotrexate; Mice; Mitomycins; Neoplasm Transplantation; Nitrosourea Compounds; Time Factors; Vincristine

1974
DTIC, CCNU, bleomycin and vincristine (BOLD) in metastatic melanoma.
    Cancer, 1980, Dec-01, Volume: 46, Issue:11

    Topics: Antineoplastic Agents; Bleomycin; Carmustine; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Humans; Lomustine; Melanoma; Thrombocytopenia; Vincristine; Vomiting

1980
Increased mutagenicity of chloroethylnitrosoureas in the presence of a rat liver S9 microsome mixture.
    Journal of the National Cancer Institute, 1983, Volume: 70, Issue:4

    Topics: Animals; Aroclors; Biotransformation; Carmustine; Chlorodiphenyl (54% Chlorine); Cyclophosphamide; Lomustine; Microsomes, Liver; Mutagenicity Tests; Mutagens; Mutation; Nitrosourea Compounds; Rats; Salmonella typhimurium; Streptozocin

1983
Therapeutic evaluation of five nitrosoureas in a human melanoma xenograft system.
    Cancer chemotherapy and pharmacology, 1983, Volume: 11, Issue:3

    Topics: Animals; Bone Marrow; Brain Neoplasms; Carmustine; Dose-Response Relationship, Drug; Female; Humans; Lomustine; Male; Melanoma; Mice; Mice, Nude; Neoplasm Transplantation; Nitrosourea Compounds; Semustine; Streptozocin; Transplantation Immunology; Transplantation, Heterologous

1983
Radiosensitizers: a conference preview.
    International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:8

    Topics: Animals; Aziridines; Buthionine Sulfoximine; Carmustine; Combined Modality Therapy; Drug Synergism; Etanidazole; Humans; Ketones; Lomustine; Maleates; Methionine Sulfoximine; Mice; Misonidazole; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents

1984
Nitroimidazoles as modifiers of nitrosourea pharmacokinetics.
    International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:9

    Topics: Animals; Antineoplastic Agents; Carmustine; Lomustine; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Nitrosourea Compounds; Radiation-Sensitizing Agents; Semustine; Streptozocin; Time Factors

1984
Clinical toxicity of combined modality treatment with nitrosourea derivatives for central nervous system tumors.
    Neurosurgery, 1982, Volume: 11, Issue:3

    Topics: Bone Marrow Diseases; Brain Neoplasms; Carmustine; Gastrointestinal Diseases; Glioblastoma; Glioma; Hematologic Diseases; Humans; Leukemia; Leukopenia; Lomustine; Meningeal Neoplasms; Nitrosourea Compounds; Sarcoma; Thrombocytopenia

1982
Induction and repair of macromolecular damage by alkylating agents.
    Cancer treatment reviews, 1984, Volume: 11 Suppl A

    Topics: Animals; Carmustine; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Colony-Forming Units Assay; DNA Repair; DNA, Single-Stranded; Drug Resistance; Fibroblasts; Humans; Lomustine; Methylnitronitrosoguanidine; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Simian virus 40

1984
Massive BACT chemotherapy with autologous bone marrow transplantation in 17 cases of non-Hodgkin's malignant lymphoma with a very bad prognosis.
    European journal of cancer & clinical oncology, 1983, Volume: 19, Issue:10

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmustine; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Female; Humans; Lomustine; Lymphoma; Male; Risk; Thioguanine; Whole-Body Irradiation

1983
Megadose chemotherapy with bone marrow rescue.
    Progress in experimental tumor research, 1984, Volume: 28

    Topics: Animals; Bone Marrow Transplantation; Brain Neoplasms; Carmustine; Combined Modality Therapy; Glioma; Humans; Lomustine; Melanoma; Neoplasms

1984
Influence of polyamine depletion caused by alpha-difluoromethylornithine, an enzyme-activated irreversible inhibitor of ornithine decarboxylase, on alkylation- and carbamoylation-induced cytotoxicity in 9L rat brain tumor cells in vitro.
    Cancer research, 1983, Volume: 43, Issue:10

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carboxy-Lyases; Carmustine; Cell Line; Cell Survival; Drug Synergism; Eflornithine; Ethylnitrosourea; Lomustine; Methylnitrosourea; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Rats

1983
Effects of structure and chemical activity on the ability of nitrosoureas to inhibit DNA repair.
    Cancer research, 1980, Volume: 40, Issue:1

    Topics: Animals; Carmustine; Cells, Cultured; DNA Repair; Leukemia L1210; Lomustine; Mice; Nitrosourea Compounds; Streptozocin; Structure-Activity Relationship

1980
Preclinical and clinical studies on chlorozotocin, a new nitrosourea with decreased bone marrow toxicity.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1980, Volume: 70

    Topics: Animals; Bone Marrow; Carmustine; Drug Evaluation; Drug Evaluation, Preclinical; Female; Humans; Leukemia L1210; Lomustine; Mice; Neoplasms; Streptozocin

1980
[State of chemotherapy and adjuvant therapies in the treatment of stomach cancer].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1984, Nov-06, Volume: 73, Issue:45

    Topics: Carmustine; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Humans; Lomustine; Male; Middle Aged; Mitomycins; Stomach Neoplasms

1984
Pharmacokinetics of nitrosoureas: comparison of 1,3-bis-(2-chloroethyl)-1-nitrosourea (BCNU) and 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) after oral and intravenous administration to rats.
    Tumori, 1984, Dec-31, Volume: 70, Issue:6

    Topics: Administration, Oral; Animals; Carmustine; Half-Life; Injections, Intravenous; Kinetics; Lomustine; Male; Rats; Rats, Inbred Strains

1984
Pulmonary fibrosis subsequent to high doses of CCNU for chronic myeloid leukemia.
    Cancer, 1983, May-15, Volume: 51, Issue:10

    Topics: Adult; Carmustine; Female; Humans; Leukemia, Myeloid; Lomustine; Male; Nitrosourea Compounds; Pulmonary Fibrosis

1983
Potentiation of cytotoxicity of anticancer agents by several different polyene antibiotics.
    Journal of the National Cancer Institute, 1984, Volume: 72, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Carmustine; Cell Survival; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Lethal Dose 50; Leukemia, Experimental; Lomustine; Mice; Mice, Inbred AKR; Polyenes

1984
[Antitumor activity of a new nitrosourea, MCNU, on a cellular morphological basis evaluated by a new in vitro antitumor sensitivity assay].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:12 Pt 1

    Topics: Animals; Antineoplastic Agents; Carmustine; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance; Humans; In Vitro Techniques; Leukemia L1210; Lomustine; Nimustine; Nitrosourea Compounds; Semustine; Tumor Stem Cell Assay

1984
The effects of BCNU (1,3-bis(2-chloroethyl)-1-nitrosourea) and CCNU (1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea) on glutathione reductase and other enzymes in mouse tissue.
    Research communications in chemical pathology and pharmacology, 1983, Volume: 40, Issue:3

    Topics: Animals; Brain; Carmustine; Enzymes; Glutathione Reductase; Liver; Lomustine; Male; Mice; Myocardium; Time Factors

1983
Effects of carbamoylation on cell survival and DNA repair in normal human embryo cells (IMR-90) treated with various 1-(2-chloroethyl)-1-nitrosoureas.
    Cancer research, 1984, Volume: 44, Issue:4

    Topics: Carmustine; Cell Line; Cell Survival; DNA; DNA Repair; DNA Replication; Ethylnitrosourea; Female; Humans; Lomustine; Lung; Nitrosourea Compounds; Pregnancy; Structure-Activity Relationship

1984
Hypoxic cells and in situ chemopotentiation of the nitrosoureas by misonidazole.
    British journal of cancer, 1984, Volume: 49, Issue:6

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Lomustine; Misonidazole; Nitroimidazoles; Oxygen; Rats; Skin Neoplasms; Tumor Stem Cell Assay

1984
Denitrosation of carcinostatic nitrosoureas by purified NADPH cytochrome P-450 reductase and rat liver microsomes to yield nitric oxide under anaerobic conditions.
    Archives of biochemistry and biophysics, 1982, Volume: 216, Issue:1

    Topics: Anaerobiosis; Animals; Biotransformation; Carmustine; Kinetics; Lomustine; Microsomes, Liver; NADP; NADPH-Ferrihemoprotein Reductase; Nitric Oxide; Nitrosourea Compounds; Oxidation-Reduction; Rats; Rats, Inbred Strains; Spectrophotometry

1982
[Chemotherapy of stomach cancer].
    Zeitschrift fur Gastroenterologie, 1982, Volume: 20, Issue:12

    Topics: Adenocarcinoma; Antineoplastic Agents; Carmustine; Cisplatin; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Fluorouracil; Gastrectomy; Humans; Lomustine; Mitomycin; Mitomycins; Neoplasm Recurrence, Local; Prognosis; Semustine; Stomach Neoplasms

1982
In vivo chemosensitization by misonidazole in sensitive and resistant tumor lines.
    Cancer research, 1983, Volume: 43, Issue:10

    Topics: Animals; Carmustine; Cell Line; Drug Resistance; Drug Synergism; Humans; Leukemia L1210; Lomustine; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Nitrosourea Compounds; Sarcoma, Experimental

1983
Proper analysis of clinical trials for malignant glioma.
    Cancer treatment reports, 1982, Volume: 66, Issue:1

    Topics: Carmustine; Glioma; Humans; Lomustine; Methods; Statistics as Topic

1982
Quantitative dose-response relations for the cytotoxic activity of chloroethylnitrosoureas in cell culture.
    Cancer research, 1982, Volume: 42, Issue:3

    Topics: Animals; Biotransformation; Brain Neoplasms; Carmustine; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Lomustine; Mustard Compounds; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Semustine; Structure-Activity Relationship; Time Factors

1982
Medulloblastoma in childhood. Multidisciplinary treatment.
    Child's brain, 1982, Volume: 9, Issue:3-4

    Topics: Adolescent; Carmustine; Cerebellar Neoplasms; Cerebellum; Child; Child, Preschool; Female; Humans; Infant; Lomustine; Male; Medulloblastoma; Neoplasm Recurrence, Local; Prognosis

1982
Modifications of DNA by different haloethylnitrosoureas.
    Cancer research, 1982, Volume: 42, Issue:11

    Topics: Animals; Carmustine; Cattle; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; DNA; Ethylnitrosourea; Lomustine; Nitrosourea Compounds; Structure-Activity Relationship; Thymus Gland

1982
The role of isocyanates in the toxicity of antitumour haloalkylnitrosoureas.
    Biochemical pharmacology, 1982, Sep-01, Volume: 31, Issue:17

    Topics: Animals; Antineoplastic Agents; Carmustine; Cyanates; Female; Leukemia L1210; Lomustine; Lymphoma; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Nitrosourea Compounds

1982
Mechanism of action of the nitrosoureas--IV. Reactions of bis-chloroethyl nitrosourea and chloroethyl cyclohexyl nitrosourea with deoxyribonucleic acid.
    Biochemical pharmacology, 1980, Oct-01, Volume: 29, Issue:19

    Topics: Animals; Carmustine; Cattle; Chemical Phenomena; Chemistry; DNA; Lomustine; Nitrosourea Compounds; Thymus Gland

1980
Metabolism of 1,3-bis(2-chloroethyl)-1-nitrosourea by rat hepatic microsomes.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:6

    Topics: Animals; Carmustine; In Vitro Techniques; Kinetics; Lomustine; Male; Microsomes, Liver; NADP; Phenobarbital; Rats; Rats, Inbred F344

1981
Mechanism of action of (2-haloethyl)nitrosoureas on DNA. Isolation and reactions of postulated 2-(alkylimino)-3-nitrosooxazolidine intermediates in the decomposition of 1,3-bis(2-chloroethyl)-, 1-(2-chloroethyl)-3-cyclohexyl-, and 1-(2-chloroethyl)-3-(4'-
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:3

    Topics: Alkylation; Antineoplastic Agents; Carmustine; Chemical Phenomena; Chemistry; DNA; Lomustine; Nitrosourea Compounds; Semustine

1981
Analysis for nitrosourea antitumor agents by gas chromatography--mass spectrometry.
    Analytical chemistry, 1981, Volume: 53, Issue:8

    Topics: Animals; Antineoplastic Agents; Carmustine; Dogs; Gas Chromatography-Mass Spectrometry; Lomustine; Nitrosourea Compounds; Semustine

1981
Nephrotoxicity of nitrosoureas.
    Cancer, 1981, Sep-15, Volume: 48, Issue:6

    Topics: Adolescent; Adult; Aged; Biopsy; Blood Urea Nitrogen; Brain Neoplasms; Carmustine; Child; Creatinine; Dose-Response Relationship, Drug; Female; Humans; Kidney; Kidney Diseases; Lomustine; Male; Middle Aged; Nitrosourea Compounds; Retrospective Studies; Semustine

1981
Chronic toxicity and carcinogenicity of cytostatic N-nitroso-(2-chloroethyl) ureas after repeated intravenous application to rats.
    Developments in toxicology and environmental science, 1980, Volume: 8

    Topics: Animals; Antineoplastic Agents; Carcinogens; Carmustine; Lomustine; Lung Neoplasms; Male; Neoplasms, Experimental; Nervous System Neoplasms; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Semustine; Stomach Neoplasms

1980
Metastatic tumor to the retina and vitreous cavity from primary melanoma of the skin: treatment with systemic and subconjunctival chemotherapy.
    Ophthalmology, 1981, Volume: 88, Issue:12

    Topics: Adult; Carmustine; Dacarbazine; Eye Neoplasms; Female; Humans; Lomustine; Melanoma; Retina; Skin Neoplasms; Vitreous Body

1981
Inhibition of tubulin polymerization by nitrosourea-derived isocyanates.
    Biochemical pharmacology, 1980, Feb-15, Volume: 29, Issue:4

    Topics: Animals; Brain; Carmustine; Cattle; Cyanates; Depression, Chemical; In Vitro Techniques; Lomustine; Microtubules; Nerve Tissue Proteins; Nitrosourea Compounds; Polymers; Swine; Tubulin

1980
Lipophilic drugs and lipoproteins: partitioning effects on chloroethylnitrosourea reaction rates in serum.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 214, Issue:2

    Topics: Carmustine; Humans; In Vitro Techniques; Kinetics; Lipids; Lipoproteins; Lomustine; Models, Biological; Nitrosourea Compounds; Semustine; Solubility

1980
Tumorigenic effect of topical mechlorethamine, BCNU and CCNU in mice.
    Experientia, 1980, Oct-15, Volume: 36, Issue:10

    Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Carmustine; Lomustine; Mechlorethamine; Mice; Neoplasms, Experimental; Nitrosourea Compounds; Papilloma; Skin Neoplasms

1980
Distribution of Bratton-Marshall-positive material in mice following intravenous injections of nitrosoureas.
    Cancer chemotherapy and pharmacology, 1980, Volume: 4, Issue:4

    Topics: Animals; Biotransformation; Carmustine; Colorimetry; Injections, Intravenous; Lomustine; Mice; Nitrosourea Compounds; Semustine; Tissue Distribution

1980
[Use of BCG as an immunoadjuvant in combination with antitumor agents in virus-induced leukemia].
    Bollettino della Societa italiana di biologia sperimentale, 1980, Oct-15, Volume: 56, Issue:19

    Topics: Animals; Antineoplastic Agents; BCG Vaccine; Carmustine; Drug Synergism; Drug Therapy, Combination; Hybridization, Genetic; Leukemia, Experimental; Lomustine; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Moloney murine leukemia virus; Neoplasm Transplantation; Semustine; Time Factors

1980
Cytotoxicity of fluoroethylating agents is potentiated by O6-benzylguanine.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:7

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Carmustine; Cell Survival; Drug Synergism; Guanine; HeLa Cells; Humans; Iodoacetamide; Lomustine; Nimustine

1996
Quantitative DNA analysis of an intracerebrally transplanted brain tumour model after experimental chemotherapy with BCNU and CCNU.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 1995, Volume: 47, Issue:4

    Topics: Animals; Brain Neoplasms; Brain Tissue Transplantation; Carmustine; Cell Division; Cytophotometry; DNA, Neoplasm; Glioma; Lomustine; Neoplasm Transplantation; Rats; Rats, Inbred Strains; Transplantation, Isogeneic; Tumor Cells, Cultured

1995
Radiation and chemotherapy improve outcome in oligodendroglioma.
    International journal of radiation oncology, biology, physics, 1997, Jan-15, Volume: 37, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Child; Child, Preschool; Combined Modality Therapy; Female; Humans; Lomustine; Male; Middle Aged; Oligodendroglioma; Procarbazine; Radiotherapy Dosage; Vincristine

1997
Induction of specific-locus and dominant lethal mutations in male mice by 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) and 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU).
    Mutation research, 1997, Oct-06, Volume: 379, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Female; Genes, Dominant; Genes, Lethal; Lomustine; Male; Mice; Mutagenesis; Mutagenicity Tests; Mutagens; Pregnancy; Spermatozoa

1997
Role of O6-methylguanine-DNA methyltransferase in the resistance of pancreatic tumors to DNA alkylating agents.
    Cancer research, 1997, Dec-01, Volume: 57, Issue:23

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents, Alkylating; Apoptosis; Carmustine; Cell Survival; Drug Resistance, Neoplasm; Female; Humans; Lomustine; Male; Middle Aged; Mitosis; Neoplasm Staging; O(6)-Methylguanine-DNA Methyltransferase; Pancreatic Neoplasms; Streptozocin; Survival Rate; Tumor Cells, Cultured

1997
Genotoxic effect of 4-aroyl-1-(2-chloroethyl)-1nitrosohydrazinecarboxamides on Saccharomyces cerevisiae cells.
    Journal of cancer research and clinical oncology, 1998, Volume: 124, Issue:6

    Topics: Antineoplastic Agents; Carmustine; Hydrazines; Lomustine; Mutagenicity Tests; Nitrosourea Compounds; Saccharomyces cerevisiae

1998
A retrospective study of the value of chemotherapy as adjuvant therapy to surgery and radiotherapy in grade 3 and 4 gliomas.
    European journal of cancer (Oxford, England : 1990), 1998, Volume: 34, Issue:10

    Topics: Administration, Oral; Adult; Age Distribution; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Glioblastoma; Humans; Infusions, Intra-Arterial; Lomustine; Middle Aged; Procarbazine; Retrospective Studies; Survival Rate; Treatment Outcome; Vincristine

1998
The minimum CD34 threshold depends on prior chemotherapy in autologous peripheral blood stem cell recipients.
    Bone marrow transplantation, 1999, Volume: 23, Issue:1

    Topics: Adolescent; Adult; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Carmustine; Combined Modality Therapy; Female; Hematologic Neoplasms; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Lomustine; Male; Mechlorethamine; Melphalan; Middle Aged; Transplantation, Autologous

1999
High-dose BEAM chemotherapy with autologous haemopoietic stem cell transplantation for Hodgkin's disease is unlikely to be associated with a major increased risk of secondary MDS/AML.
    British journal of cancer, 1999, Volume: 81, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Child; Child, Preschool; Chlorambucil; Cohort Studies; Combined Modality Therapy; Cytarabine; Doxorubicin; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Hodgkin Disease; Humans; Incidence; Infant; Leukemia, Myeloid; Life Tables; Lomustine; Male; Mechlorethamine; Melphalan; Middle Aged; Myelodysplastic Syndromes; Neoplasms, Second Primary; Podophyllotoxin; Prednisolone; Prednisone; Procarbazine; Retrospective Studies; Risk; Salvage Therapy; Vinblastine; Vincristine

1999
Procarbazine, lomustine, and vincristine (PCV) chemotherapy for anaplastic astrocytoma: A retrospective review of radiation therapy oncology group protocols comparing survival with carmustine or PCV adjuvant chemotherapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1999, Volume: 17, Issue:11

    Topics: Adult; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Carmustine; Combined Modality Therapy; Female; Humans; Karnofsky Performance Status; Lomustine; Male; Middle Aged; Procarbazine; Randomized Controlled Trials as Topic; Retrospective Studies; Survival Analysis; Vincristine

1999
Comparison of DNA lesions produced by tumor-inhibitory 1,2-bis(sulfonyl)hydrazines and chloroethylnitrosoureas.
    Biochemical pharmacology, 2000, Feb-01, Volume: 59, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Bacteriophage T7; Carmustine; Cross-Linking Reagents; DNA; DNA Damage; DNA, Viral; Isocyanates; Lomustine; Semustine

2000
Poly(ADP-ribose) polymerase-independent potentiation of nitrosourea cytotoxicity by 3-aminobenzamide in human malignant glioma cells.
    European journal of pharmacology, 2000, Jun-16, Volume: 398, Issue:2

    Topics: Benzamides; Binding Sites; Carmustine; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; G2 Phase; Glioma; Humans; Lomustine; Methylnitrosourea; Mitosis; Nimustine; Nitrosourea Compounds; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Tumor Cells, Cultured

2000
Locally delivered chemotherapy and repeated surgery can improve survival in glioblastoma patients.
    Italian journal of neurological sciences, 1999, Volume: 20, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Disease Progression; Disease-Free Survival; Drug Evaluation; Glioblastoma; Humans; Injections, Spinal; Lomustine; Middle Aged; Mitoxantrone; Neoplasm Recurrence, Local; Procarbazine; Radiotherapy, Adjuvant; Reoperation; Survival Analysis; Treatment Outcome; Vincristine

1999
Effects of carmustine and lomustine on arylamine N-acetyltransferase activity and 2-aminofluorene-DNA adducts in rat glial tumor cells.
    Neurochemical research, 2000, Volume: 25, Issue:6

    Topics: Animals; Arylamine N-Acetyltransferase; Brain Neoplasms; Carmustine; DNA Adducts; Fluorenes; Glioma; Kinetics; Lomustine; Rats; Tumor Cells, Cultured

2000
Protection of hematopoietic cells from O(6)-alkylation damage by O(6)-methylguanine DNA methyltransferase gene transfer: studies with different O(6)-alkylating agents and retroviral backbones.
    European journal of haematology, 2001, Volume: 67, Issue:1

    Topics: Alkylating Agents; Alkylation; Animals; Carmustine; Cells, Cultured; Colony-Forming Units Assay; Dacarbazine; DNA Damage; DNA, Complementary; Drug Resistance; Genetic Vectors; Hematopoietic Stem Cells; Humans; Lomustine; Mice; Moloney murine leukemia virus; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Recombinant Fusion Proteins; Retroviridae; Sarcoma Viruses, Murine; Spleen Focus-Forming Viruses; Temozolomide; Terminal Repeat Sequences; Transfection

2001
Combination chemotherapy with carmustine and cisplatin followed by procarbazine, lomustine, and vincristine for adult high-grade astrocytoma.
    Chang Gung medical journal, 2005, Volume: 28, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustine; Cisplatin; Female; Glioblastoma; Humans; Lomustine; Male; Middle Aged; Procarbazine; Vincristine

2005
Nitrosourea efficacy in high-grade glioma: a survival gain analysis summarizing 504 cohorts with 24193 patients.
    Journal of neuro-oncology, 2008, Volume: 88, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Cohort Studies; Data Interpretation, Statistical; Databases, Factual; Female; Glioblastoma; Glioma; Humans; Lomustine; Male; Nimustine; Nitrosourea Compounds; Reproducibility of Results; Selection Bias; Survival Analysis; Treatment Outcome

2008
High-dose chemotherapy with autologous stem cell transplantation in adults with recurrent embryonal tumors of the central nervous system.
    Cancer, 2008, Apr-15, Volume: 112, Issue:8

    Topics: Adult; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Central Nervous System Neoplasms; Cisplatin; Cohort Studies; Disease Progression; Etoposide; Female; Follow-Up Studies; Humans; Lomustine; Male; Medulloblastoma; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Procarbazine; Retrospective Studies; Stem Cell Transplantation; Survival Rate; Thiotepa; Transplantation, Autologous

2008
[Chemotherapy and renal toxicity].
    Bulletin du cancer, 2008, May-28, Volume: 95 FMC Onco

    Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Carboplatin; Carmustine; Cisplatin; Deoxycytidine; Gemcitabine; Humans; Kidney; Kidney Diseases; Lomustine; Methotrexate; Organoplatinum Compounds; Oxaliplatin

2008
[Clinical features and combined treatment of the central nervous system in Hodgkin's disease].
    Voprosy onkologii, 2008, Volume: 54, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Child; Female; Hodgkin Disease; Humans; Lomustine; Male; Methylnitrosourea; Middle Aged; Prognosis; Radiotherapy, Adjuvant; Retrospective Studies; Risk Factors; Spinal Cord Compression; Survival Analysis; Treatment Outcome; Young Adult

2008
[Retrospective analysis of 24 recurrent glioblastoma after chemoradiation and treated with nitrosoureas or irinotecan and bevacizumab].
    Bulletin du cancer, 2012, Feb-01, Volume: 99, Issue:2

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Camptothecin; Carmustine; Chemoradiotherapy; Chemotherapy, Adjuvant; Cohort Studies; Dacarbazine; Drug Therapy, Combination; Glioblastoma; Humans; Irinotecan; Lomustine; Middle Aged; Neoplasm Recurrence, Local; Nitrosourea Compounds; Radiation-Sensitizing Agents; Retrospective Studies; Temozolomide

2012
Prolonged survival associated with the use of intraoperative carmustine (Gliadel) in a paediatric patient with recurrent grade III astrocytoma.
    British journal of neurosurgery, 2013, Volume: 27, Issue:4

    Topics: Adolescent; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Astrocytoma; Carmustine; Combined Modality Therapy; Drug Implants; Female; Humans; Lomustine; Neoplasm Recurrence, Local; Procarbazine; Time Factors; Treatment Outcome

2013
Retrospective study of carmustine or lomustine with bevacizumab in recurrent glioblastoma patients who have failed prior bevacizumab.
    Neuro-oncology, 2014, Volume: 16, Issue:11

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Carmustine; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Glioblastoma; Humans; Lomustine; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Retrospective Studies; Salvage Therapy; Survival Rate; Young Adult

2014
LACE versus BEAM conditioning in relapsed and refractory lymphoma transplant: retrospective multicenter analysis of toxicity and efficacy.
    International journal of hematology, 2016, Volume: 103, Issue:3

    Topics: Adolescent; Adult; Autografts; Carmustine; Child; Child, Preschool; Cohort Studies; Cyclophosphamide; Cytarabine; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Hodgkin Disease; Humans; Lomustine; Lymphoma, Non-Hodgkin; Male; Melphalan; Middle Aged; Multicenter Studies as Topic; Retrospective Studies; Survival Rate; Transplantation Conditioning; Young Adult

2016
A retrospective comparison of toxicity and initial efficacy of two autologous stem cell transplant conditioning regimens for relapsed lymphoma: LEAM and BEAM.
    Bone marrow transplantation, 2016, Volume: 51, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cytarabine; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Lomustine; Lymphoma; Male; Melphalan; Middle Aged; Retrospective Studies; Salvage Therapy; Survival Analysis; Transplantation Conditioning; Transplantation, Autologous

2016
Substituting carmustine for lomustine is safe and effective in the treatment of relapsed or refractory Lymphoma-a retrospective study from the BSBMT (BEAM versus LEAM).
    Bone marrow transplantation, 2021, Volume: 56, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cytarabine; Etoposide; Humans; Lomustine; Lymphoma; Melphalan; Retrospective Studies; Transplantation Conditioning; Transplantation, Autologous

2021
CRISPR/Cas9-induced knockout reveals the role of ABCB1 in the response to temozolomide, carmustine and lomustine in glioblastoma multiforme.
    Pharmacological research, 2022, Volume: 185

    Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Carmustine; Cell Line, Tumor; CRISPR-Cas Systems; Drug Resistance, Neoplasm; Glioblastoma; Humans; Lomustine; Neoplasm Proteins; Temozolomide

2022