carmustine and ethylnitrosourea

carmustine has been researched along with ethylnitrosourea in 41 studies

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-199028 (68.29)18.7374
1990's10 (24.39)18.2507
2000's3 (7.32)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fox, P; Green, D; Nagourney, R; Panasci, LC; Schein, PS1
Kann, HE1
Eisenbrand, G; Fiebig, HH; Zeller, WJ1
Brundrett, RB; Colvin, M; Cowens, W; Jardine, I; Ludlum, DB1
Agradi, E; Paoletti, P; Pezzotta, S1
Tokuda, K1
Eberle, G; Huh, NH; Nehls, P; Rajewsky, MF; Thomale, J1
Eisenbrand, G; Krauth-Siegel, RL; Schirmer, RH; Stahl, W1
Dive, C; Watson, JV; Workman, P1
D'Incalci, M; Day, R; Erickson, LC; Kohn, KW; Kornblith, PL; Laurent, G; Sariban, E; Smith, BH; Zlotogorski, C1
Ducore, JM1
Denkel, E; Eisenbrand, G; Müller, N; Sterzel, W1
Ludlum, DB1
Carchman, RA; Carter, WH; Chinchilli, VM; Solana, RP; Wilson, JD1
Dean, PN; Deen, DF; Gray, JW; Linfoot, PA; Marton, LJ1
Kovatch, RM; Lijinsky, W; Singer, SS1
Allen, EB; Bhat, UG; Chauhan, SM; Koganty, RR; Lown, JW; Sapse, AM1
Kacinski, BM; Ludlum, DB; Rupp, WD1
Ducore, JM; Rosenstein, BS2
Aida, T; Berger, MS; Bodell, WJ; Rosenblum, ML1
Dolan, ME; Weinkam, RJ1
Bedford, P; Eisenbrand, G1
Bedford, P; Berger, MR; Eisenbrand, G; Schmähl, D1
Deen, DF; Marton, LJ; Oredsson, SM1
Dornish, JM; Markussen, G; Smith-Kielland, I1
Erickson, LC; Kohn, KW; Sariban, E1
Habs, M; Ivankovic, S; Schmähl, D; Zeller, WJ1
Kohn, KW; Ludlum, DB; Tong, WP1
Fiebig, HH; Schmähl, D; Strobel, H1
Buschfort, C; Müller, MR; Rajewsky, MF; Seeber, S; Seiler, F; Thomale, J1
Berger, SJ; Donovan, C; Gerson, SL; Varnes, ME1
Gwilt, PR; Lawson, T1
Bodell, WJ; Chen, FX; Church, KM; Gold, B; Zhang, Y1
Buschfort, C; Lensing, C; Müller, MR; Rajewsky, MF; Seeber, S; Thomale, J1
Brent, TP; Edwards, CC; Harris, LC; Houghton, PJ; Marathi, UK; Sorrentino, BP; Srivastava, DK; Vanin, EF1
Bibby, MC; Margison, GP; McElhinney, RS; Rafferty, JA; Thompson, MJ1
Gerson, SL; Phillips, WP1
Bodell, WJ; Dhananjaya, N; Giannini, DD; Miller, DL; Sprung, CN; Wang, YP1
Debiton, E; Glasser, AL; Madelmont, JC; Marchenay, C; Maurizis, JC; Rolhion, C1
Bodell, WJ1

Reviews

1 review(s) available for carmustine and ethylnitrosourea

ArticleYear
DNA adducts and DNA damage by antineoplastic and carcinogenic N-nitrosocompounds.
    Journal of cancer research and clinical oncology, 1986, Volume: 112, Issue:3

    Topics: Alkylation; Animals; Antineoplastic Agents; Carcinogens; Carmustine; Chemical Phenomena; Chemistry; DNA; Ethylnitrosourea; Liver Neoplasms; Lomustine; Mammary Neoplasms, Experimental; Nitrosourea Compounds; Nucleic Acid Conformation

1986

Other Studies

40 other study(ies) available for carmustine and ethylnitrosourea

ArticleYear
A structure-activity analysis of chemical and biological parameters of chloroethylnitrosoureas in mice.
    Cancer research, 1977, Volume: 37, Issue:8 Pt 1

    Topics: Alkylation; Animals; Bone Marrow; Carmustine; Ethyl Chloride; Ethylnitrosourea; Half-Life; Leukemia L1210; Leukocyte Count; Lomustine; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Neutrophils; Nitrosourea Compounds; Statistics as Topic; Streptozocin; Structure-Activity Relationship

1977
Comparison of biochemical and biological effects of four nitrosoureas with differing carbamoylating activities.
    Cancer research, 1978, Volume: 38, Issue:8

    Topics: Animals; Carmustine; Cell Survival; Cells, Cultured; Chemical Phenomena; Chemistry; DNA, Neoplasm; Ethylnitrosourea; Leukemia L1210; Lomustine; Neoplasm Proteins; Nitrosourea Compounds; RNA, Neoplasm; Streptozocin; Time Factors

1978
Chemotherapeutic activity of new 2-chloroethylnitrosoureas in rat L5222 leukemia: comparison of bifunctional and water-soluble derivatives with 1,3-bis(2-chloroethyl)-1-nitrosourea.
    Journal of the National Cancer Institute, 1978, Volume: 60, Issue:2

    Topics: Animals; Carmustine; Ethylnitrosourea; Female; Leukemia, Experimental; Male; Rats; Rats, Inbred Strains; Solubility; Water

1978
A chemical basis for the antitumor activity of chloroethylnitrosoureas.
    Biochemical pharmacology, 1976, Mar-15, Volume: 25, Issue:6

    Topics: Animals; Antineoplastic Agents; Buffers; Carmustine; Chemical Phenomena; Chemistry; Ethylnitrosourea; Ions; Leukemia L1210; Lomustine; Nitrosourea Compounds; Solutions; Time Factors

1976
The effect of BCNU, CCNU and MeCCNU in the prevention of the development of tumors of the nervous system.
    Pharmacological research communications, 1975, Volume: 07, Issue:1

    Topics: Animals; Brain Neoplasms; Carmustine; Ethylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Semustine

1975
[Effect of pretreatment with N-methyl-N-nitrosourea or streptozotocin on the cytotoxicity and the induction of sister chromatid exchanges in human and rodent brain tumor cells treated with chloroethylnitrosourea].
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1992, Volume: 67, Issue:4

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Survival; Drug Resistance; Drug Synergism; Ethylnitrosourea; Glioma; Methylnitrosourea; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Rats; Rats, Inbred F344; Sister Chromatid Exchange; Streptozocin; Tumor Cells, Cultured

1992
Repair of O6-ethylguanine in DNA protects rat 208F cells from tumorigenic conversion by N-ethyl-N-nitrosourea.
    Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:24

    Topics: Animals; Carmustine; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Clone Cells; DNA; DNA Repair; Ethylnitrosourea; Guanine; Kinetics; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Rats

1990
A method to determine the carbamoylating potential of 1-(2-chloroethyl)-1-nitrosoureas.
    IARC scientific publications, 1987, Issue:84

    Topics: Alkylating Agents; Carbamates; Carmustine; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Dithionitrobenzoic Acid; Ethylnitrosourea; Glutathione; Humans; Nitrosourea Compounds; Semustine; Streptozocin

1987
Inhibition of intracellular esterases by antitumour chloroethylnitrosoureas. Measurement by flow cytometry and correlation with molecular carbamoylation activity.
    Biochemical pharmacology, 1988, Oct-15, Volume: 37, Issue:20

    Topics: Animals; Antineoplastic Agents; Carmustine; Esterases; Ethylnitrosourea; Flow Cytometry; Lomustine; Mice; Proteins; Spectrometry, Fluorescence; Streptozocin; Structure-Activity Relationship

1988
DNA cross-linking responses of human malignant glioma cell strains to chloroethylnitrosoureas, cisplatin, and diaziquone.
    Cancer research, 1987, Aug-01, Volume: 47, Issue:15

    Topics: Aziridines; Benzoquinones; Brain Neoplasms; Carmustine; Cells, Cultured; Cisplatin; Cross-Linking Reagents; DNA Damage; DNA, Neoplasm; Drug Resistance; Ethylnitrosourea; Glioblastoma; Humans; Neoplasm Proteins; Nitrosourea Compounds

1987
alpha-Difluoromethylornithine effects on nitrosourea-induced cytotoxicity and crosslinking in a methylation excision repair positive (MER+) human cell line.
    Biochemical pharmacology, 1987, Jul-01, Volume: 36, Issue:13

    Topics: Burkitt Lymphoma; Carmustine; Cell Line; Cell Survival; DNA; DNA Repair; Eflornithine; Ethylnitrosourea; Humans; Methylation; Methyltransferases; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase

1987
Nature and biological significance of DNA modification by the haloethylnitrosoureas.
    IARC scientific publications, 1986, Issue:78

    Topics: Antineoplastic Agents; Carmustine; Chromatography, High Pressure Liquid; Cross-Linking Reagents; DNA; DNA Damage; DNA Repair; Ethylnitrosourea; Lomustine; Nitrosourea Compounds; Spectrophotometry, Ultraviolet; Structure-Activity Relationship

1986
Evaluation of the interaction of three genotoxic agents in eliciting sister-chromatid exchanges using response surface methodology.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1987, Volume: 9, Issue:3

    Topics: Animals; Carmustine; Cell Line; Cisplatin; Data Interpretation, Statistical; Ethylnitrosourea; Sister Chromatid Exchange

1987
Effect of cell cycle position on the survival of 9L cells treated with nitrosoureas that alkylate, cross-link, and carbamoylate.
    Cancer research, 1986, Volume: 46, Issue:5

    Topics: Alkylating Agents; Animals; Brain Neoplasms; Carbamates; Carmustine; Cell Cycle; Cell Line; Cell Survival; Cross-Linking Reagents; Ethylnitrosourea; Lomustine; Nitroso Compounds; Nitrosourea Compounds; Rats; Structure-Activity Relationship

1986
Carcinogenesis in F-344 rats induced by nitrosohydroxyalkyl-chloroethylureas.
    Journal of cancer research and clinical oncology, 1986, Volume: 112, Issue:3

    Topics: Animals; Carmustine; Ethylnitrosourea; Female; Lomustine; Magnetic Resonance Spectroscopy; Male; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Rats, Inbred F344; Rats, Inbred Strains

1986
Isolation and characterization of electrophiles from 2-haloethylnitrosoureas forming cytotoxic DNA cross-links and cyclic nucleotide adducts and the analysis of base site-selectivity by ab initio calculations.
    IARC scientific publications, 1986, Issue:70

    Topics: Alkylation; Carmustine; Chemical Phenomena; Chemistry; Cross-Linking Reagents; Cytidine; DNA; DNA Damage; Ethylnitrosourea; Guanosine

1986
Repair of haloethylnitrosourea-induced DNA damage in mutant and adapted bacteria.
    Cancer research, 1985, Volume: 45, Issue:12 Pt 1

    Topics: Alkylation; Carmustine; DNA Repair; Dose-Response Relationship, Drug; Escherichia coli; Ethylnitrosourea; Methylnitronitrosoguanidine; Mutation; Rec A Recombinases; Recombination, Genetic

1985
Theophylline release of replicon initiation inhibition by nitrosoureas correlates with the synergistic killing in L1210 leukemia in vitro.
    Mutation research, 1985, Volume: 146, Issue:1

    Topics: Animals; Carmustine; Cell Survival; Cells, Cultured; DNA, Neoplasm; Drug Synergism; Ethylnitrosourea; Leukemia L1210; Mice; Replicon; Theophylline

1985
Repair of O6-(2-chloroethyl)guanine mediates the biological effects of chloroethylnitrosoureas.
    Environmental health perspectives, 1985, Volume: 62

    Topics: Alkylation; Animals; Carmustine; Cell Line; Cell Survival; DNA; DNA Repair; Drug Resistance; Ethylnitrosourea; Guanine; Kinetics; L Cells; Methyltransferases; Mice; O(6)-Methylguanine-DNA Methyltransferase; Sister Chromatid Exchange

1985
An analysis of 1-(2-chloroethyl)-1-nitrosourea activity at the cellular level.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:11

    Topics: Animals; Antineoplastic Agents; Carmustine; Cell Survival; Drug Evaluation, Preclinical; Ethylnitrosourea; Leukemia L1210; Leukemia P388; Lomustine; Mice; Nitrosourea Compounds; Streptozocin; Structure-Activity Relationship

1983
DNA damage and repair in the bone marrow of rats treated with four chloroethylnitrosoureas.
    Cancer research, 1984, Volume: 44, Issue:2

    Topics: Animals; Bone Marrow; Carcinogens; Carmustine; DNA Repair; Ethylnitrosourea; Female; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Streptozocin

1984
The level of DNA interstrand crosslinking in bone marrow parallels the extent of myelosuppression in mice treated with four chloroethylnitrosoureas.
    Journal of cancer research and clinical oncology, 1984, Volume: 108, Issue:1

    Topics: Animals; Antineoplastic Agents; Bone Marrow; Carmustine; DNA; Ethylnitrosourea; Hematopoietic Stem Cells; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Nitrosourea Compounds; Streptozocin

1984
Influence of polyamine depletion caused by alpha-difluoromethylornithine, an enzyme-activated irreversible inhibitor of ornithine decarboxylase, on alkylation- and carbamoylation-induced cytotoxicity in 9L rat brain tumor cells in vitro.
    Cancer research, 1983, Volume: 43, Issue:10

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carboxy-Lyases; Carmustine; Cell Line; Cell Survival; Drug Synergism; Eflornithine; Ethylnitrosourea; Lomustine; Methylnitrosourea; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Rats

1983
Inhibition of protein A24 lyase by nitrosoureas.
    FEBS letters, 1984, Oct-29, Volume: 176, Issue:2

    Topics: Animals; Carcinoma, Ehrlich Tumor; Carmustine; Cyanates; Ethyl Methanesulfonate; Ethylnitrosourea; Histones; Isocyanates; Lyases; Methyl Methanesulfonate; Methylnitrosourea; Nitrosourea Compounds; Ubiquitins

1984
Theophylline does not reverse DNA replicon initiation inhibition in human cells resistant to alkylating agent-theophylline killing synergism.
    Chemico-biological interactions, 1984, Sep-15, Volume: 51, Issue:2

    Topics: Alkylating Agents; Burkitt Lymphoma; Carmustine; Cell Line; Cell Survival; Cisplatin; Cross-Linking Reagents; DNA, Neoplasm; Drug Resistance; Drug Synergism; Ethylnitrosourea; Humans; Melphalan; Replicon; Theophylline

1984
Effects of carbamoylation on cell survival and DNA repair in normal human embryo cells (IMR-90) treated with various 1-(2-chloroethyl)-1-nitrosoureas.
    Cancer research, 1984, Volume: 44, Issue:4

    Topics: Carmustine; Cell Line; Cell Survival; DNA; DNA Repair; DNA Replication; Ethylnitrosourea; Female; Humans; Lomustine; Lung; Nitrosourea Compounds; Pregnancy; Structure-Activity Relationship

1984
Experimental chemical production of brain tumors.
    Annals of the New York Academy of Sciences, 1982, Volume: 381

    Topics: Animals; Brain Neoplasms; Carmustine; Ethylnitrosourea; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Rats

1982
Modifications of DNA by different haloethylnitrosoureas.
    Cancer research, 1982, Volume: 42, Issue:11

    Topics: Animals; Carmustine; Cattle; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; DNA; Ethylnitrosourea; Lomustine; Nitrosourea Compounds; Structure-Activity Relationship; Thymus Gland

1982
Experimental chemotherapy with N'N'-bis(2-chloroethyl)-N-nitrosourea (BCNU) in autochthonous neurogenic tumors of the rat transplacentally induced by ethylnitrosourea.
    Journal of cancer research and clinical oncology, 1982, Volume: 104, Issue:1-2

    Topics: Animals; Carmustine; Disease Models, Animal; Ethylnitrosourea; Female; Fetus; Maternal-Fetal Exchange; Neoplasms, Experimental; Nervous System Neoplasms; Pregnancy; Rats

1982
Capacity of individual chronic lymphatic leukemia lymphocytes and leukemic blast cells for repair of O6-ethylguanine in DNA: relation to chemosensitivity in vitro and treatment outcome.
    Cancer research, 1994, Aug-15, Volume: 54, Issue:16

    Topics: Acute Disease; Carmustine; Cyclophosphamide; Cytarabine; DNA Repair; Doxorubicin; Drug Resistance; Ethylnitrosourea; Glutathione; Guanine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid; Lymphocytes; Treatment Outcome

1994
Combined depletion of O6-alkylguanine-DNA alkyltransferase and glutathione to modulate nitrosourea resistance in breast cancer.
    Biochemical pharmacology, 1994, Aug-03, Volume: 48, Issue:3

    Topics: Breast Neoplasms; Carmustine; Cell Line; Cell Survival; Drug Resistance; Ethylnitrosourea; Glutathione; Glutathione Transferase; Guanine; Humans; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase

1994
Clofibrate enhances the DNA damaging action and cytotoxicity of nitrosoureas.
    Cancer letters, 1993, Jun-15, Volume: 70, Issue:1-2

    Topics: Animals; Carmustine; Cell Survival; Clofibrate; DNA Damage; DNA, Neoplasm; Drug Synergism; Ethylnitrosourea; Leukemia L1210; Mice

1993
DNA crosslinking, sister chromatid exchange and cytotoxicity of N-2-chloroethylnitrosoureas tethered to minor groove binding peptides.
    Carcinogenesis, 1993, Volume: 14, Issue:5

    Topics: Alkylation; Animals; Base Sequence; Carcinogens; Carmustine; Cell Survival; Dipeptides; DNA; Ethylnitrosourea; Kinetics; Leukemia L1210; Mice; Molecular Sequence Data; Plasmids; Sister Chromatid Exchange; Time Factors; Tumor Cells, Cultured

1993
DNA repair and cellular resistance to alkylating agents in chronic lymphocytic leukemia.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1997, Volume: 3, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cell Nucleus; Chlorambucil; Cyclophosphamide; DNA Damage; DNA Repair; DNA, Neoplasm; Drug Resistance, Neoplasm; Ethylnitrosourea; Guanine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Prednisone; Vincristine

1997
Retroviral transfer of a bacterial alkyltransferase gene into murine bone marrow protects against chloroethylnitrosourea cytotoxicity.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1995, Volume: 1, Issue:11

    Topics: Animals; Antineoplastic Agents, Alkylating; Bacterial Proteins; Bone Marrow; Carmustine; Enzyme Inhibitors; Escherichia coli Proteins; Ethylnitrosourea; Feasibility Studies; Gene Transfer Techniques; Guanine; Mice; Mice, Inbred CBA; O(6)-Methylguanine-DNA Methyltransferase; Retroviridae; Transcription Factors

1995
Influence of O6-benzylguanine on the anti-tumour activity and normal tissue toxicity of 1,3-bis(2-chloroethyl)-1-nitrosourea and molecular combinations of 5-fluorouracil and 2-chloroethyl-1-nitrosourea in mice.
    British journal of cancer, 1999, Volume: 79, Issue:9-10

    Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Colony-Forming Units Assay; Drug Combinations; Drug Resistance, Neoplasm; Enzyme Inhibitors; Ethylnitrosourea; Fluorouracil; Guanine; Humans; Male; Mice; Mice, Nude; O(6)-Methylguanine-DNA Methyltransferase; Tumor Stem Cell Assay

1999
Acquired resistance to O6-benzylguanine plus chloroethylnitrosoureas in human breast cancer.
    Cancer chemotherapy and pharmacology, 1999, Volume: 44, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carmustine; Drug Resistance, Neoplasm; Drug Synergism; Ethylnitrosourea; Glutathione; Guanine; Humans; O(6)-Methylguanine-DNA Methyltransferase; Tumor Cells, Cultured

1999
Induction of lacI mutations in Big Blue Rat-2 cells treated with 1-(2-hydroxyethyl)-1-nitrosourea: a model system for the analysis of mutagenic potential of the hydroxyethyl adducts produced by 1,3-bis (2-chloroethyl)-1-nitrosourea.
    Mutation research, 2001, Dec-12, Volume: 484, Issue:1-2

    Topics: Animals; Bacterial Proteins; Base Sequence; Carmustine; Cell Line; Deoxyguanosine; DNA Adducts; DNA Mutational Analysis; Escherichia coli Proteins; Ethylnitrosourea; Guanine; Lac Repressors; Mutagenicity Tests; Mutagens; Mutation; Rats; Repressor Proteins

2001
Inhibition of O6-alkylguanine-DNA alkyltransferase by O6-benzyl-N2-acetylguanosine increases chloroethylnitrosourea-induced apoptosis in Mer+ human melanoma cells.
    Melanoma research, 2002, Volume: 12, Issue:5

    Topics: Animals; Apoptosis; Carmustine; Cattle; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethylnitrosourea; Guanosine; Humans; Melanoma; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase; Time Factors; Tumor Cells, Cultured

2002
DNA alkylation products formed by 1-(2-chloroethyl)-1-nitrosourea as molecular dosimeters of therapeutic response.
    Journal of neuro-oncology, 2009, Volume: 91, Issue:3

    Topics: Alkylation; Antineoplastic Agents, Alkylating; Carmustine; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; DNA Adducts; DNA Modification Methylases; DNA Repair Enzymes; Ethylnitrosourea; Glioma; Humans; Statistics as Topic; Tumor Suppressor Proteins

2009