carmustine and eflornithine

carmustine has been researched along with eflornithine in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199020 (80.00)18.7374
1990's4 (16.00)18.2507
2000's0 (0.00)29.6817
2010's1 (4.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Deen, DF; Hunter, KJ; Marton, LJ; Pellarin, M1
Ahmann, DL; Creagan, ET; Frytak, S; Schaid, DJ1
Seidenfeld, J; Sprague, WS1
Huben, RP; Pegg, AE; Pine, MJ1
Deen, DF; Hunter, KJ; Marton, LJ2
Chamberlain, M; Levin, V; Prados, M; Rodriguez, L; Silver, P1
Cohen, AR; Cravioto, H; Flamm, ES; Pietronigro, DD1
Ducore, JM1
Barnes, D; Block, AL; Erickson, LC; Seidenfeld, J1
Komar, KA; Seidenfeld, J1
Deen, DF; Feuerstein, BG; Marton, LJ1
Bjerkvig, R; Deen, DF; Linden, M; Marton, LJ; Oredsson, SM1
Deen, DF; Feuerstein, BG; Marton, LJ; Oredsson, SM; Rosenblum, ML; Tofilon, PJ1
Deen, DF; Marton, LJ; Oredsson, SM1
Deen, DF; Marton, LJ; Tofilon, PJ1
Deen, DF; Marton, LJ; Oredsson, SM; Sano, Y1
Alhonen-Hongisto, L; Deen, DF; Marton, LJ1
Cavanaugh, PF; Pavelic, ZP; Porter, CW1
Deen, DF; Hung, DT; Marton, LJ; Seidenfeld, J1
Hervatin, SJ; Koch-Weser, J; Levin, VA; Marton, LJ; McCann, PP; Sjoerdsma, A1
Marton, LJ1
Deen, DF; Marton, LJ; Oredsson, SM; Tofilon, PJ1
Afzal, V; Feeney, L; Wolff, S1

Trials

1 trial(s) available for carmustine and eflornithine

ArticleYear
Disseminated malignant melanoma and recombinant interferon: analysis of seven consecutive phase II investigations.
    The Journal of investigative dermatology, 1990, Volume: 95, Issue:6 Suppl

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Drug Evaluation; Eflornithine; Female; Humans; Interferon alpha-2; Interferon-alpha; Interferon-gamma; Male; Melanoma; Middle Aged; Recombinant Proteins; Time Factors

1990

Other Studies

24 other study(ies) available for carmustine and eflornithine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Effect of alpha-difluoromethylornithine on 1,3-bis(2-chloroethyl)-1-nitrosourea and cis-diamminedichloroplatinum(II) cytotoxicity, DNA interstrand cross-linking, and growth in human brain tumor cell lines in vitro.
    Cancer research, 1990, May-01, Volume: 50, Issue:9

    Topics: Biogenic Polyamines; Brain Neoplasms; Carmustine; Cell Line; Cell Survival; Cisplatin; DNA; Eflornithine; Humans; Tumor Cells, Cultured

1990
Comparisons between sensitive and resistant human tumor cell lines regarding effects of polyamine depletion on chloroethylnitrosourea efficacy.
    Cancer research, 1990, Feb-01, Volume: 50, Issue:3

    Topics: Carmustine; Cell Survival; DNA Repair; Drug Synergism; Eflornithine; Humans; In Vitro Techniques; Methylation; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Polyamines; Putrescine; Streptozocin; Tumor Cells, Cultured

1990
Production of N1-acetyl spermidine by renal cell tumors.
    The Journal of urology, 1989, Volume: 141, Issue:3

    Topics: Animals; Carcinoma, Renal Cell; Carmustine; Eflornithine; Female; Kidney Neoplasms; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Rats; Spermidine; Tumor Cells, Cultured

1989
Differential response to 1,3-bis (2-chloroethyl)-1-nitrosourea in drug-resistant and -sensitive 9L rat brain tumor cells pretreated with alpha-difluoromethylornithine and 6-thioguanine.
    International journal of cancer, 1989, Oct-15, Volume: 44, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cell Line; Drug Evaluation, Preclinical; Drug Resistance; Drug Synergism; Eflornithine; Flow Cytometry; Rats; Thioguanine; Tumor Cells, Cultured; Tumor Stem Cell Assay

1989
Treatment of recurrent gliomas with 1,3-bis(2-chloroethyl)-1-nitrosourea and alpha-difluoromethylornithine.
    Neurosurgery, 1989, Volume: 24, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustine; Combined Modality Therapy; Eflornithine; Glioblastoma; Humans; Neoplasm Recurrence, Local

1989
Effect of difluoromethylornithine on the antiglioma therapeutic efficacy of intra-arterial BCNU.
    Journal of neurosurgery, 1986, Volume: 65, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Eflornithine; Glioma; Injections, Intra-Arterial; Male; Neoplasm Transplantation; Rats; Rats, Inbred F344; Time Factors

1986
alpha-Difluoromethylornithine effects on nitrosourea-induced cytotoxicity and crosslinking in a methylation excision repair positive (MER+) human cell line.
    Biochemical pharmacology, 1987, Jul-01, Volume: 36, Issue:13

    Topics: Burkitt Lymphoma; Carmustine; Cell Line; Cell Survival; DNA; DNA Repair; Eflornithine; Ethylnitrosourea; Humans; Methylation; Methyltransferases; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase

1987
Comparison of DNA interstrand cross-linking and strand breakage by 1,3-bis(2-chloroethyl)-1-nitrosourea in polyamine-depleted and control human adenocarcinoma cells.
    Cancer research, 1987, Sep-01, Volume: 47, Issue:17

    Topics: Adenocarcinoma; Carmustine; Cell Survival; Cells, Cultured; DNA Damage; DNA, Neoplasm; Eflornithine; Humans; Polyamines

1987
Changes in the glutathione content of rat 9L cells induced by treatment with the ornithine decarboxylase inhibitor alpha-difluoromethylornithine.
    Cancer research, 1987, Oct-15, Volume: 47, Issue:20

    Topics: Alkylating Agents; Animals; Buthionine Sulfoximine; Carmustine; Eflornithine; Glutathione; Methionine Sulfoximine; Ornithine Decarboxylase Inhibitors; Putrescine; Rats; Spermidine

1987
Chemosensitization of cultured human carcinoma cells to 1,3-bis(2-chloroethyl)-1-nitrosourea by difluoromethylornithine-induced polyamine depletion.
    Cancer research, 1985, Volume: 45, Issue:5

    Topics: Carmustine; Cell Division; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Eflornithine; Humans; Neoplasms; Ornithine; Ornithine Decarboxylase; Polyamines

1985
Effects of dicyclohexylamine sulfate, a spermidine synthase inhibitor, in 9L rat brain tumor cells.
    Cancer research, 1985, Volume: 45, Issue:10

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Cycle; Cell Survival; Cyclohexylamines; Eflornithine; Mitoguazone; Ornithine; Polyamines; Putrescine; Rats; Spermidine Synthase; Transferases

1985
Cell cycle age response of 9L cells to 1,3-bis(2-chloroethyl)-1-nitrosourea and modification by alpha-difluoromethylornithine.
    Cancer research, 1983, Volume: 43, Issue:4

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carmustine; Cell Cycle; Cell Line; Eflornithine; Kinetics; Neoplasms, Experimental; Ornithine; Rats

1983
Differential potentiation of 1,3-bis(2-chloroethyl)-1-nitrosourea by alpha-difluoromethylornithine in chloroethylnitrosourea-sensitive and -resistant 9L rat brain tumor cells in vitro.
    Cancer research, 1983, Volume: 43, Issue:8

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carmustine; Cell Line; Drug Resistance; Drug Synergism; Eflornithine; Ornithine; Polyamines; Rats; Sister Chromatid Exchange

1983
Influence of polyamine depletion caused by alpha-difluoromethylornithine, an enzyme-activated irreversible inhibitor of ornithine decarboxylase, on alkylation- and carbamoylation-induced cytotoxicity in 9L rat brain tumor cells in vitro.
    Cancer research, 1983, Volume: 43, Issue:10

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carboxy-Lyases; Carmustine; Cell Line; Cell Survival; Drug Synergism; Eflornithine; Ethylnitrosourea; Lomustine; Methylnitrosourea; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Rats

1983
alpha-Difluoromethylornithine-induced polyamine depletion of 9L tumor cells modifies drug-induced DNA cross-link formation.
    Science (New York, N.Y.), 1983, Dec-09, Volume: 222, Issue:4628

    Topics: Animals; Carmustine; Cells, Cultured; Cisplatin; Cross-Linking Reagents; DNA; Eflornithine; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Rats

1983
Effects of alpha-difluoromethylornithine on the growth of 9L rat brain tumor multicellular spheroids and their response to 1,3-bis(2-chloroethyl)-1-nitrosourea.
    Cancer research, 1984, Volume: 44, Issue:2

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carmustine; Cell Division; Cell Survival; Drug Therapy, Combination; Eflornithine; Ornithine; Polyamines; Rats

1984
Time dependence of the potentiation of 1,3-bis(2-chloroethyl)-1-nitrosourea cytotoxicity caused by alpha-difluoromethylornithine-induced polyamine depletion in 9L rat brain tumor cells.
    Cancer research, 1984, Volume: 44, Issue:5

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Line; Drug Synergism; Eflornithine; Kinetics; Ornithine; Ornithine Decarboxylase Inhibitors; Putrescine; Rats; Spermidine

1984
Enhancement of 1,3-bis(2-chloroethyl)-1-nitrosourea-induced cytotoxicity and DNA damage by alpha-difluoromethylornithine in L1210 leukemia cells.
    Cancer research, 1984, Volume: 44, Issue:9

    Topics: Animals; Carmustine; Cell Survival; DNA, Neoplasm; Drug Synergism; Eflornithine; Kinetics; Leukemia L1210; Mice; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Spermine

1984
Sensitization of 9L rat brain gliosarcoma cells to 1,3-bis(2-chloroethyl)-1-nitrosourea by alpha-difluoromethylornithine, an ornithine decarboxylase inhibitor.
    Cancer research, 1981, Volume: 41, Issue:7

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Cycle; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Eflornithine; Glioma; Kinetics; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Rats

1981
Potentiation of the antitumor therapeutic effects of 1,3-bis(2-chloroethyl)-1-nitrosourea by alpha-difluoromethylornithine, an ornithine decarboxylase inhibitor.
    Cancer research, 1981, Volume: 41, Issue:11 Pt 1

    Topics: Animals; Brain Neoplasms; Carmustine; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Eflornithine; Male; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Ornithine; Rats; Rats, Inbred F344; Time Factors

1981
An approach to the use of polyamine inhibitors for cancer therapy.
    Medical biology, 1981, Volume: 59, Issue:5-6

    Topics: Animals; Antimetabolites, Antineoplastic; Brain Neoplasms; Carmustine; Drug Therapy, Combination; Eflornithine; Neoplasms, Experimental; Ornithine; Polyamines; Rats

1981
Polyamine depletion influences drug-induced chromosomal damage.
    Science (New York, N.Y.), 1982, Sep-10, Volume: 217, Issue:4564

    Topics: Animals; Carmustine; Chromosomes; Cisplatin; DNA; Eflornithine; Nucleic Acid Conformation; Ornithine; Polyamines; Putrescine; Rats; Sister Chromatid Exchange; Spermidine; Spermine

1982
Depletion of cellular polyamines by alpha-difluoromethylornithine increases 1,3-bis(2-chloroethyl)-1-nitrosourea-induced sister-chromatid exchanges.
    Mutation research, 1993, Volume: 289, Issue:1

    Topics: Animals; Carmustine; Cell Survival; Cells, Cultured; Eflornithine; Nucleic Acid Conformation; Polyamines; Putrescine; Rats; Sister Chromatid Exchange; Spermidine

1993