carmustine has been researched along with acetaminophen in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (37.04) | 18.7374 |
| 1990's | 6 (22.22) | 18.2507 |
| 2000's | 5 (18.52) | 29.6817 |
| 2010's | 6 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Farber, JL; Harman, AW; Kyle, ME; Serroni, A | 1 |
| Farber, JL; Kinugasa, T; Konishi, Y; Maruyama, H; Nakae, D; Yamamoto, K; Yoshiji, H | 1 |
| Farber, JL; Kyle, ME; Sakaida, I; Serroni, A | 1 |
| Adamson, GM; Harman, AW | 2 |
| Hayes, MA; Murray, CA; Rushmore, TH | 1 |
| Gotlieb, AI; Hayes, MA; Koo, EW; Wong, MK | 1 |
| Farber, JL; Kyle, ME; Miccadei, S; Nakae, D | 1 |
| Cotgreave, IA; Harvison, PJ; Moldéus, P; Nelson, SD; Porubek, DJ; Rundgren, M | 1 |
| Farber, JL; Kyle, ME; Nakae, D; Serroni, A | 1 |
| Farber, JL; Kyle, ME; Leonard, TB; Nakae, D; Rogers, SA; Serroni, A | 1 |
| Farber, JL; Nakae, D; Oakes, JW | 1 |
| Harvison, PJ; Moldéus, P; Nelson, SD; Porubek, DJ; Rundgren, M | 1 |
| de Vries, J; Debets, AJ; van de Straat, R; Vermeulen, NP | 1 |
| Claude, JR; Dutertre-Catella, H; Ellouk-Achard, S; Levresse, V; Martin, C; Pham-Huy, C; Thevenin, M; Warnet, JM | 1 |
| Harada, T; Hiraishi, H; Ito, Y; Ivey, KJ; Ogonuki, H; Razandi, M; Suzuki, Y; Terano, A | 1 |
| Chang, C; Chapman, PB; Fleisher, M; Hwu, WJ; Krown, SE; Livingston, PO; Pinto, JT; Williams, L; Wolchok, JD | 1 |
1 trial(s) available for carmustine and acetaminophen
| Article | Year |
|---|---|
Phase I trial of high dose paracetamol and carmustine in patients with metastatic melanoma.
Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Antineoplastic Agents, Alkylating; Carmustine; Cohort Studies; Dose-Response Relationship, Drug; Female; Free Radical Scavengers; Glutathione; Glutathione Reductase; Humans; Leukocytes, Mononuclear; Liver Neoplasms; Lymphatic Metastasis; Male; Maximum Tolerated Dose; Melanoma; Neoplasm Metastasis; Skin Neoplasms; Time Factors | 2003 |
26 other study(ies) available for carmustine and acetaminophen
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
The killing of cultured hepatocytes by N-acetyl-p-benzoquinone imine (NAPQI) as a model of the cytotoxicity of acetaminophen.
Topics: Acetaminophen; Acidosis; Adenosine Triphosphate; Animals; Benzoflavones; Benzoquinones; beta-Naphthoflavone; Carmustine; Cell Survival; Cells, Cultured; Deferoxamine; Glutathione; Glutathione Reductase; Imines; In Vitro Techniques; Liver; Models, Biological; Monensin; Oxidation-Reduction; Phenylenediamines; Rats | 1991 |
Liposome-encapsulated superoxide dismutase prevents liver necrosis induced by acetaminophen.
Topics: Acetaminophen; Animals; Carmustine; Chemical and Drug Induced Liver Injury; Drug Synergism; Glutathione; Lipid Peroxides; Liposomes; Male; Rats; Rats, Inbred Strains; Superoxide Dismutase; Superoxides | 1990 |
Metabolism of acetaminophen by cultured rat hepatocytes. Depletion of protein thiol groups without any loss of viability.
Topics: Acetaminophen; Animals; Carmustine; Cells, Cultured; Deferoxamine; Glutathione; Glutathione Disulfide; Liver; Male; Phenylenediamines; Proteins; Rats; Rats, Inbred Strains; Sulfhydryl Compounds | 1990 |
A role for the glutathione peroxidase/reductase enzyme system in the protection from paracetamol toxicity in isolated mouse hepatocytes.
Topics: Acetaminophen; Age Factors; Animals; Benzoquinones; Carmustine; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Imines; In Vitro Techniques; Liver; Mice; Oxidation-Reduction; Peroxides; tert-Butylhydroperoxide | 1989 |
Influences of glutathione status on different cytocidal responses of monolayer rat hepatocytes exposed to aflatoxin B1 or acetaminophen.
Topics: Acetaminophen; Acetylcysteine; Aflatoxin B1; Aflatoxins; Animals; Carmustine; Cells, Cultured; Drug Interactions; Glutathione; L-Lactate Dehydrogenase; Liver; Male; Rats; Rats, Inbred F344 | 1986 |
Aflatoxin B1 and acetaminophen induce different cytoskeletal responses during prelethal hepatocyte injury.
Topics: Acetaminophen; Actin Cytoskeleton; Actins; Aflatoxin B1; Aflatoxins; Animals; Carmustine; Cell Survival; Cells, Cultured; Cytoskeleton; Liver; Male; Microscopy, Fluorescence; Pseudopodia; Rats; Rats, Inbred F344 | 1987 |
Superoxide dismutase and catalase protect cultured hepatocytes from the cytotoxicity of acetaminophen.
Topics: Acetaminophen; Animals; Benzoflavones; beta-Naphthoflavone; Carmustine; Catalase; Chlorides; Deferoxamine; Drug Resistance; Ferric Compounds; Ferrous Compounds; Free Radicals; Liver; Male; Mannitol; Methylcholanthrene; Mixed Function Oxygenases; Rats; Rats, Inbred Strains; Superoxide Dismutase | 1987 |
Comparative cytotoxic effects of N-acetyl-p-benzoquinone imine and two dimethylated analogues.
Topics: Acetaminophen; Animals; Benzoquinones; Carmustine; Cell Survival; Chemical Phenomena; Chemistry; Deferoxamine; Dithiothreitol; Dose-Response Relationship, Drug; Glutathione; Imines; Lipid Peroxides; Liver; Oxidation-Reduction; Oxygen; Rats; Structure-Activity Relationship | 1988 |
1,3-(2-Chloroethyl)-1-nitrosourea potentiates the toxicity of acetaminophen both in the phenobarbital-induced rat and in hepatocytes cultured from such animals.
Topics: Acetaminophen; Acetone; Carmustine; Cell Survival; Deferoxamine; Drug Synergism; Enzyme Induction; Glutathione; Liver; Male; Maleates; Methylcholanthrene; Phenobarbital; Phenylenediamines | 1988 |
Peroxidation-dependent and peroxidation-independent mechanisms by which acetaminophen kills cultured rat hepatocytes.
Topics: Acetaminophen; Animals; Carmustine; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Lipid Peroxides; Liver; Male; Membrane Lipids; Methylcholanthrene; Phenylenediamines; Phospholipids; Rats; Rats, Inbred Strains; Time Factors | 1988 |
Potentiation in the intact rat of the hepatotoxicity of acetaminophen by 1,3-bis(2-chloroethyl)-1-nitrosourea.
Topics: Acetaminophen; Animals; Carmustine; Chemical and Drug Induced Liver Injury; Deferoxamine; Drug Synergism; Glutathione Reductase; Male; Methylcholanthrene; Rats; Rats, Inbred Strains | 1988 |
Investigation of mechanisms of acetaminophen toxicity in isolated rat hepatocytes with the acetaminophen analogues 3,5-dimethylacetaminophen and 2,6-dimethylacetaminophen.
Topics: Acetaminophen; Animals; Carmustine; Dithiothreitol; Glutathione; Glutathione Reductase; In Vitro Techniques; Kinetics; Lipid Peroxides; Liver; Male; Maleates; Rats; Rats, Inbred Strains | 1987 |
The mechanism of prevention of paracetamol-induced hepatotoxicity by 3,5-dialkyl substitution. The roles of glutathione depletion and oxidative stress.
Topics: Acetaminophen; Animals; Benzoquinones; Carmustine; Chemical and Drug Induced Liver Injury; Glutathione; Imines; Lipid Peroxides; Liver; Liver Diseases; Male; Maleates; Oxidation-Reduction; Quinones; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1987 |
Ex vivo and in vitro models in acetaminophen hepatotoxicity studies. Relationship between glutathione depletion, oxidative stress and disturbances in calcium homeostasis and energy metabolism.
Topics: Acetaminophen; Animals; Calcium; Carmustine; Chemical and Drug Induced Liver Injury; Cytosol; Energy Metabolism; Glutathione; Glutathione Reductase; Homeostasis; Male; Methylcholanthrene; Oxidative Stress; Rats; Rats, Wistar | 1995 |
Role of iron and glutathione redox cycle in acetaminophen-induced cytotoxicity to cultured rat hepatocytes.
Topics: Acetaminophen; Amitrole; Animals; Carmustine; Catalase; Cells, Cultured; Chromium Radioisotopes; Cytochrome P-450 Enzyme System; Deferoxamine; Glutathione; Glutathione Reductase; Iron; L-Lactate Dehydrogenase; Liver; Male; Maleates; Methylcholanthrene; Oxidation-Reduction; Phenanthrolines; Rats; Rats, Sprague-Dawley | 1994 |
Oxidative stress in cultured hepatocytes exposed to acetaminophen.
Topics: Acetaminophen; Animals; Carmustine; Cells, Cultured; Deferoxamine; Glutathione; Glutathione Disulfide; Liver; Male; Mice | 1993 |