carglumic acid has been researched along with arginine in 29 studies
| Studies (carglumic acid) | Trials (carglumic acid) | Recent Studies (post-2010) (carglumic acid) | Studies (arginine) | Trials (arginine) | Recent Studies (post-2010) (arginine) |
|---|---|---|---|---|---|
| 129 | 18 | 87 | 46,388 | 1,688 | 11,176 |
| Protein | Taxonomy | carglumic acid (IC50) | arginine (IC50) |
|---|---|---|---|
| Cationic amino acid transporter 3 | Homo sapiens (human) | 283 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.45) | 18.7374 |
| 1990's | 3 (10.34) | 18.2507 |
| 2000's | 1 (3.45) | 29.6817 |
| 2010's | 22 (75.86) | 24.3611 |
| 2020's | 2 (6.90) | 2.80 |
| Authors | Studies |
|---|---|
| Alvaro, I; Arilla, E; Bodega, G; Boyano, MC | 1 |
| Lyftogt, C; Raphael, D; Zieve, L | 1 |
| Bardet, J; Cadoudal, M; Drouin, V; Kuchler, G; Meyer-Gast, D; Poggi-Travert, F; Rabier, D; Saudubray, JM | 1 |
| Cho, H; Kim, S; Kim, WH; Kwak, YS; Lee, JH; Paik, WK | 1 |
| Cho, H; Jeon, SH; Kim, S; Kim, WH; Lee, JH; Paik, WK; Park, H; Yun, C | 1 |
| Gao, Y; Geng, M; Hou, Y; Ruan, Z; Wang, L; Wu, G; Wu, X; Yin, Y; Zhou, X | 1 |
| Blachier, F; Geng, MM; Liu, XD; Liu, YQ; Wu, GY; Wu, X; Yang, HS; Yin, YL | 1 |
| Deng, ZY; Huang, RL; Li, TJ; Liu, XD; Liu, YQ; Liu, ZQ; Ruan, Z; Wu, X; Yin, YL | 1 |
| Bellantuono, R; Bellino, V; De Palo, T; Favia, V; Morrone, A; Papadia, F; Ranieri, A; Tummolo, A | 1 |
| Cao, W; Chen, X; Fang, T; Jia, G; Liu, G; Wang, J; Wu, C; Xiao, L; Zhao, H | 1 |
| Deng, M; Ma, T; Nie, H; Sun, L; Wang, F; Wang, Z; Zhang, G; Zhang, H | 1 |
| Cai, J; Cao, W; Chen, X; Fang, T; Jia, G; Liu, G; Wang, J; Wu, C; Wu, X; Xiao, L; Zhao, H | 1 |
| Deng, MT; Guo, RH; Ma, TW; Sun, LW; Wang, F; Wang, ZY; Zhang, GM; Zhang, H | 1 |
| Fan, Y; Guo, Y; Nie, H; Sun, L; Wang, F; Zhang, G; Zhang, H | 1 |
| Liu, Y; Qiao, S; Ye, C; Ye, Q; Zeng, X; Zhu, J | 1 |
| Bai, JH; Chen, ZL; Feng, T; Liu, Y; Spicer, LJ; Xu, XL | 1 |
| Feng, T; Morrell, BC; Perego, MC; Schütz, LF; Spicer, LJ | 1 |
| Dong, L; Loor, JJ; Peng, A; Wang, H; Wang, M; Yu, L; Zhang, H; Zhao, F | 1 |
| Du, X; Li, J; Luo, L; Wang, C; Wang, L; Xu, Q; Zhao, Z | 1 |
| Abreu, MLT; Palencia, JYP; Pospissil Garbossa, CA; Saraiva, A; Schinckel, AP; Zangeronimo, MG | 1 |
| Guo, S; Loor, JJ; Peng, A; Wang, H; Wang, M; Zhang, H | 1 |
| Fan, Y; Guo, Y; Sun, L; Wang, F; Wang, Z; Zhang, H | 1 |
| Loor, JJ; Ma, T; Nie, H; Wang, F; Wang, Z; Zhang, H; Zhao, F | 1 |
| Chen, P; Gu, X; Huang, HY; Liang, XF; Wu, XF; Xue, M | 1 |
| Coleman, DN; Guo, S; Loor, JJ; Peng, A; Wang, H; Wang, M; Yu, Y; Zhang, H | 1 |
| Guo, S; Loor, JJ; Peng, A; Sun, H; Wang, H; Wang, M; Zhang, H | 1 |
| DeVore, AA; Feng, T; Morrell, BC; Perego, MC; Spicer, LJ | 1 |
| Elsabagh, M; Loor, JJ; Ma, Y; Wang, H; Wang, M; Zhang, H | 1 |
| Caldovic, L; Haskins, N; McNutt, M; Morizono, H; Senkevitch, E; Sonaimuthu, P; Tuchman, M; Uapinyoying, P | 1 |
1 review(s) available for carglumic acid and arginine
| Article | Year |
|---|---|
Effectiveness of citrulline and N-carbamoyl glutamate as arginine precursors on reproductive performance in mammals: A systematic review.
Topics: Animal Feed; Animals; Arginine; Birth Weight; Citrulline; Dietary Supplements; Female; Fetal Development; Fetus; Glutamates; Goats; Mammals; Pregnancy; Rats; Reproduction; Sheep | 2018 |
1 trial(s) available for carglumic acid and arginine
| Article | Year |
|---|---|
Effect of dietary arginine and N-carbamoylglutamate supplementation on reproduction and gene expression of eNOS, VEGFA and PlGF1 in placenta in late pregnancy of sows.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Arginine; Diet; Dietary Supplements; Female; Glutamates; Litter Size; Maternal Nutritional Physiological Phenomena; Nitric Oxide Synthase Type III; Placenta Growth Factor; Pregnancy; Pregnancy Proteins; Reverse Transcriptase Polymerase Chain Reaction; Swine; Vascular Endothelial Growth Factor A | 2012 |
27 other study(ies) available for carglumic acid and arginine
| Article | Year |
|---|---|
Somatostatin binding reduced by ammonium acetate in the rat hippocampus can be reversed by treatment with N-carbamyl-L-glutamate plus L-arginine.
Topics: Acetates; Ammonia; Animals; Arginine; Drug Administration Schedule; Female; Glutamates; Glutamine; Hippocampus; Rats; Rats, Wistar; Receptors, Somatostatin; Somatostatin; Time Factors | 1992 |
Ammonia toxicity: comparative protective effect of various arginine and ornithine derivatives, aspartate, benzoate, and carbamyl glutamate.
Topics: Ammonia; Ammonium Chloride; Animals; Arginine; Aspartic Acid; Benzoates; Brain Diseases; Coma; Dose-Response Relationship, Drug; Glutamates; Male; Rats; Rats, Inbred Strains | 1986 |
Therapeutic use of carbamylglutamate in the case of carbamoyl-phosphate synthetase deficiency.
Topics: Ammonia; Arginine; Carbamoyl-Phosphate Synthase (Ammonia); Child, Preschool; Citrulline; Glutamates; Glutamic Acid; Glutamine; Humans; Male | 1996 |
N-carbamoyl-L-glutamate plus L-arginine can protect ammonia intoxication in rats with reduced functional liver mass.
Topics: Acetates; Ammonia; Animals; Arginine; Behavior, Animal; Blood Urea Nitrogen; Glutamates; Hepatectomy; Liver; Liver Diseases; Male; Organ Size; Rats; Rats, Sprague-Dawley | 1998 |
Mixture of N-carbamoyl-L-glutamate plus L-arginine can protect rats with liver cirrhosis from acute ammonia intoxication.
Topics: Acetates; Acute Disease; Ammonia; Animals; Arginine; Behavior, Animal; Carbamoyl-Phosphate Synthase (Ammonia); Dimethylnitrosamine; Drug Synergism; Glutamates; Liver Cirrhosis; Male; Poisoning; Rats; Rats, Sprague-Dawley; Time Factors | 2001 |
Dietary supplementation with L-arginine or N-carbamylglutamate enhances intestinal growth and heat shock protein-70 expression in weanling pigs fed a corn- and soybean meal-based diet.
Topics: Animal Feed; Animals; Arginine; Dietary Supplements; Female; Gene Expression; Glutamates; Glycine max; HSP70 Heat-Shock Proteins; Intestine, Small; Male; Sus scrofa; Weaning; Zea mays | 2010 |
Effects of dietary L-arginine or N-carbamylglutamate supplementation during late gestation of sows on the miR-15b/16, miR-221/222, VEGFA and eNOS expression in umbilical vein.
Topics: Animal Feed; Animals; Arginine; Birth Weight; Dietary Supplements; Female; Fetal Development; Fetus; Gene Expression; Genetic Fitness; Glutamates; MicroRNAs; Nitric Oxide Synthase Type III; Pregnancy; Pregnancy, Animal; Real-Time Polymerase Chain Reaction; Swine; Umbilical Cord; Vascular Endothelial Growth Factor A | 2012 |
Successful early management of a female patient with a metabolic stroke due to ornithine transcarbamylase deficiency.
Topics: Adolescent; Arginine; Brain; Carnitine; Case Management; Citrulline; Coma; Combined Modality Therapy; Drug Therapy, Combination; Electroencephalography; Female; Glutamates; Hemofiltration; Humans; Hyperammonemia; Lethargy; Ornithine Carbamoyltransferase Deficiency Disease; Phenylbutyrates; Renal Dialysis; Tomography, Emission-Computed, Single-Photon; Vomiting | 2013 |
Changes in the metabolome of rats after exposure to arginine and N-carbamylglutamate in combination with diquat, a compound that causes oxidative stress, assessed by 1H NMR spectroscopy.
Topics: Alanine Transaminase; Amino Acids; Animals; Arginine; Aspartate Aminotransferases; Diquat; Energy Metabolism; Female; Gastrointestinal Microbiome; Glutamates; Magnetic Resonance Spectroscopy; Metabolome; Multivariate Analysis; Oxidative Stress; Rats; Rats, Sprague-Dawley | 2016 |
N-carbamylglutamate and L-arginine improved maternal and placental development in underfed ewes.
Topics: Animal Nutritional Physiological Phenomena; Animals; Arginine; Female; Fetal Development; Fetal Growth Retardation; Glutamates; Maternal Nutritional Physiological Phenomena; Placenta; Pregnancy; Sheep | 2016 |
Dietary arginine and N-carbamylglutamate supplementation enhances the antioxidant statuses of the liver and plasma against oxidative stress in rats.
Topics: Analysis of Variance; Animals; Antioxidants; Arginine; Catalase; Diet; Dietary Supplements; Diquat; Enzyme Activation; Female; Glutamates; Glutathione; Hydroxyl Radical; Lipid Peroxidation; Liver; Malondialdehyde; Nitrogen; Oxidative Stress; Plasma; Rats; Rats, Sprague-Dawley; Superoxides | 2016 |
Dietary -carbamylglutamate and rumen-protected -arginine supplementation ameliorate fetal growth restriction in undernourished ewes.
Topics: 3-Hydroxybutyric Acid; Amniotic Fluid; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Arginine; Diet; Dietary Supplements; Female; Fetal Development; Fetal Growth Retardation; Glutamates; Nutritional Requirements; Polyamines; Pregnancy; Prenatal Nutritional Physiological Phenomena; Rumen; Sheep | 2016 |
Metabolomic profiling in umbilical venous plasma reveals effects of dietary rumen-protected arginine or N-carbamylglutamate supplementation in nutrient-restricted Hu sheep during pregnancy.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Arginine; Diet; Dietary Supplements; Female; Fetal Blood; Fetus; Glutamates; Metabolome; Pregnancy; Rumen; Sheep | 2017 |
Dietary N-Carbamylglutamate Supplementation in a Reduced Protein Diet Affects Carcass Traits and the Profile of Muscle Amino Acids and Fatty Acids in Finishing Pigs.
Topics: Amino Acids; Animal Feed; Animals; Arginine; Diet, Protein-Restricted; Dietary Supplements; Glutamates; Leucine; Meat; Muscles; Swine | 2017 |
Effects of N-carbamylglutamate and L-arginine on gonadotrophin-releasing hormone (GnRH) gene expression and secretion in GT1-7 cells.
Topics: Animals; Arginine; Cell Line; Cell Proliferation; Estrogen Receptor alpha; Gene Expression; Glutamates; Gonadotropin-Releasing Hormone; Kisspeptins; Mice; Neurons; Nitric Oxide Synthase Type I; Receptors, Kisspeptin-1 | 2018 |
Effects of N-carbamylglutamate and L-arginine on steroidogenesis and gene expression in bovine granulosa cells.
Topics: Animals; Arginine; Cattle; Cells, Cultured; Culture Media; Cytochrome P-450 Enzyme System; Female; Follicle Stimulating Hormone; Gene Expression Regulation; Glutamates; Granulosa Cells; Insulin-Like Growth Factor I; Membrane Transport Proteins; RNA, Messenger | 2018 |
Effects of Dietary l-Arginine and N-Carbamylglutamate Supplementation on Intestinal Integrity, Immune Function, and Oxidative Status in Intrauterine-Growth-Retarded Suckling Lambs.
Topics: Animals; Arginine; Dietary Supplements; Fetal Growth Retardation; Glutamates; Interleukin-6; Intestinal Mucosa; Intestines; Myeloid Differentiation Factor 88; Oxidative Stress; Sheep; Sheep Diseases; Superoxide Dismutase-1; Toll-Like Receptor 4; Zonula Occludens-1 Protein | 2018 |
Effect of N-carbamoylglutamate supplementation on the growth performance, antioxidant status and immune response of mirror carp (Cyprinus carpio) fed an arginine-deficient diet.
Topics: Animal Feed; Animals; Antioxidants; Arginine; Carps; Diet; Dietary Supplements; Dose-Response Relationship, Drug; Glutamates; Immunity, Innate | 2019 |
Dietary N-carbamylglutamate and l-arginine supplementation improves intestinal energy status in intrauterine-growth-retarded suckling lambs.
Topics: Animal Feed; Animals; Arginine; Dietary Supplements; Energy Metabolism; Female; Fetal Growth Retardation; Glutamates; Intestinal Mucosa; Jejunum; Male; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Sheep; Sirtuin 1 | 2019 |
Dietary rumen-protected arginine and N-carbamylglutamate supplementation enhances fetal growth in underfed ewes.
Topics: Animal Nutritional Physiological Phenomena; Animals; Arginine; Diet; Dietary Supplements; Embryonic Development; Female; Glutamates; Malnutrition; Pregnancy; Sheep | 2018 |
Dietary N-carbamylglutamate and rumen-protected L-arginine supplementation during intrauterine growth restriction in undernourished ewes improve fetal thymus development and immune function.
Topics: Animal Nutritional Physiological Phenomena; Animals; Arginine; Diet; Dietary Supplements; Female; Fetal Development; Fetal Growth Retardation; Glutamates; Immune System; Maternal Nutritional Physiological Phenomena; Pregnancy; Sheep; Thymus Gland | 2018 |
Dietary N-Carbamylglutamate (NCG) alleviates liver metabolic disease and hepatocyte apoptosis by suppressing ERK1/2-mTOR-S6K1 signal pathway via promoting endogenous arginine synthesis in Japanese seabass (Lateolabrax japonicus).
Topics: Animal Feed; Animals; Apoptosis; Arginine; Bass; Diet; Dietary Supplements; Dose-Response Relationship, Drug; Fish Diseases; Fish Proteins; Glutamates; Hepatocytes; Liver Diseases; Metabolic Diseases; Nutrients; Random Allocation; Signal Transduction | 2019 |
N-Carbamylglutamate and l-Arginine Promote Intestinal Absorption of Amino Acids by Regulating the mTOR Signaling Pathway and Amino Acid and Peptide Transporters in Suckling Lambs with Intrauterine Growth Restriction.
Topics: Amino Acid Transport Systems; Amino Acids; Animals; Animals, Newborn; Arginine; Disease Models, Animal; Female; Fetal Growth Retardation; Glutamates; Intestinal Absorption; Membrane Transport Proteins; Nitric Oxide; Pregnancy; RNA, Messenger; Sheep, Domestic; Signal Transduction; TOR Serine-Threonine Kinases | 2019 |
N-carbamylglutamate and l-arginine promote intestinal function in suckling lambs with intrauterine growth restriction by regulating antioxidant capacity via a nitric oxide-dependent pathway.
Topics: Animal Feed; Animals; Antioxidants; Arginine; Catalase; Dietary Supplements; Female; Fetal Growth Retardation; Glutamates; Glutathione Peroxidase; Intestinal Mucosa; Male; NF-E2 Transcription Factor; Sheep; Sheep Diseases; Superoxide Dismutase | 2019 |
Effects of N-carbamylglutamate and arginine on steroidogenesis and proliferation of pig granulosa cells in vitro.
Topics: Animals; Arginine; Cell Proliferation; Cells, Cultured; Estradiol; Female; Glutamates; Gonadal Steroid Hormones; Granulosa Cells; Progesterone; Swine | 2019 |
Dietary supplementation of l-arginine and N-carbamylglutamate enhances duodenal barrier and mitochondrial functions and suppresses duodenal inflammation and mitophagy in suckling lambs suffering from intrauterine-growth-restriction.
Topics: Animal Feed; Animals; Animals, Suckling; Arginine; Dietary Supplements; Fetal Growth Retardation; Glutamates; Random Allocation; Sheep | 2020 |
Gene delivery corrects N-acetylglutamate synthase deficiency and enables insights in the physiological impact of L-arginine activation of N-acetylglutamate synthase.
Topics: Amino-Acid N-Acetyltransferase; Animals; Arginine; Citrulline; Dependovirus; Disease Models, Animal; Gene Transfer Techniques; Glutamates; Humans; Hyperammonemia; Mice; Mice, Knockout; Mutant Proteins; Urea; Urea Cycle Disorders, Inborn | 2021 |