cardiovascular-agents has been researched along with acteoside* in 1 studies
1 other study(ies) available for cardiovascular-agents and acteoside
| Article | Year |
|---|---|
Mechanism of action of verbascoside on the isolated rat heart: increases in level of prostacyclin.
The mechanism of the positive cardioactive effects induced by verbascoside in the Lagendorff rat heart has been investigated. Isolated rat hearts treated with alpha- or beta-adrenergic agents did not show significant reduction of the positive chronotropism, inotropism and increased coronary perfusion rate mediated by verbascoside. A significant increase in prostacyclin levels (142%) observed following the administration of verbascoside suggests that prostacyclin stimulates formation of cAMP which induces the cardioactivity associated with verbascoside. Topics: Animals; Cardiovascular Agents; Epoprostenol; Female; Glucosides; Heart; In Vitro Techniques; Male; Myocardium; Phenols; Rats; Rats, Wistar | 1999 |