cardiovascular-agents has been researched along with acemetacin* in 1 studies
1 other study(ies) available for cardiovascular-agents and acemetacin
| Article | Year |
|---|---|
[Interaction of coronary-active compounds and anti-inflammatory drugs on the coronary vascular system (author's transl)].
The effect of acemetacin (Rantudil) and indomethacin, respectively, on coronary flow and O2-pressure in coronary sinus blood before and after i.v. injections of coronary active compounds was permanently registered in anesthetised closed-chest dogs. It was found that i.v. infections of 2 mg acemetacin/kg extended effects of i.v. injected morocromen. After administration of morocromen (4.0 mg/kg), carbocromen (2.0 mg/kg), or dipyridamole (0.4 mg/kg) the application of acemetacin or indomethacin, respectively, produced a markedly increased effect on the coronary blood vessels. Comparative studies of indole-derivatives, the Ca-antagonizing compounds prenylamine, verapamil, nifedipine, and the phosphodiesterase inhibitor papaverine showed no similar effects. Topics: Animals; Anti-Inflammatory Agents; Cardiovascular Agents; Chromonar; Coronary Circulation; Coumarins; Dipyridamole; Dogs; Drug Interactions; Female; Indoleacetic Acids; Indomethacin; Male; Morpholines; Myocardium; Oxygen Consumption | 1981 |