carcinine and carnosine

carcinine has been researched along with carnosine in 45 studies

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-19905 (11.11)18.7374
1990's10 (22.22)18.2507
2000's6 (13.33)29.6817
2010's21 (46.67)24.3611
2020's3 (6.67)2.80

Authors

AuthorsStudies
Dutkiewicz, M; Filipek, S; Kowalewska, M; Koziak, K; Krzeczyński, P; Niewieczerzał, S; Trzaskowski, B; Zegrocka-Stendel, O; Żyżyńska-Granica, B1
Arnould, JM; Frentz, R1
Fisher, H; Fitzpatrick, JC; Flancbaum, L1
Brotman, DN; Fisher, H; Fitzpatrick, JC; Flancbaum, L; Kasziba, E; Van Es, T1
Brotman, DN; Fisher, H; Flancbaum, L; Kang, YH; Merrill, GF1
Arnould, JM3
Arnould, JM; Tankosic, C1
Evstigneeva, RP; Kubatiev, AA; Rozhkova, EA; Tkachenko, SB; Zheltukhina, GA1
Ageyeva, EA; Babizhayev, MA; Evstigneeva, RP; Gueyne, J; Seguin, MC; Zheltukhina, GA1
Ageeva, EA; Babizhaev, MA; Evstigneeva, RP; Zheltukhina, GA1
Evstigneeva, RP; Grigor'ev, DN; Rozhkova, EA; Zheltukhina, GA1
Notterman, DA; Steinberg, C1
Babizhayev, MA; Lozovskaya, EL; Lul'kin, YA; Makareyeva, EN; Sapezhinskii, II1
Gérardin-Charbonnier, C; Ozer, MS; Rodehüser, L; Selve, C; Thiébaut, S1
Borycz, J; Borycz, JA; Loubani, M; Meinertzhagen, IA1
Chen, Z; Hu, WW; Jin, CL; Sakurai, E; Xu, LS; Yanai, K1
Chen, Z; Hu, W; Jin, C; Kato, M; Kiso, Y; Sakurai, E; Watanabe, T; Wei, E; Yanai, K1
Arkosi, Z; Gajda, T; Henry, B; Korecz, L; Paksi, Z; Rockenbauer, A1
Babizhayev, MA4
Arruda, SE; Dolph, PJ; Gavin, BA1
Aust, S; Brüsselbach, F; Hovemann, BT; Pütz, S1
Babizhayev, MA; Yegorov, YE2
Babizhayev, MA; Nikolayev, GM; Nikolayeva, JG; Yegorov, YE1
Babizhayev, MA; Deyev, AI; Lankin, VZ; Savel'yeva, EL; Yegorov, YE1
Babizhayev, MA; Kasus-Jacobi, A; Khoroshilova-Maslova, IP1
Borycz, J; Borycz, JA; Boulianne, GL; Edwards, TN; Meinertzhagen, IA1
Babizhayev, MA; Kasus-Jacobi, A; Li, F; Marchette, LD; Wang, H1
Chaturvedi, R; Li, HS; Reddig, K1
Babizhayev, MA; Kasus-Jacobi, A; Vishnyakova, KS; Yegorov, YE1
Dovengerds, C; Hartwig, S; Herrmann, C; Hovemann, BT1
Krämer, H; Moehlman, AT; Stenesen, D1
Borman, RP; Denno, ME; Privman, E; Venton, BJ; Wolin, DC1
Chaturvedi, R; Guo, P; Li, HS; Luan, Z1
Dyrynda, EA; Smith, VJ; Suleiman, S1
Carroll, L; Davies, MJ; Karton, A; Pattison, DI; Radom, L1
Krämer, H; Moehlman, AT; Rodan, AR; Schellinger, JN; Stenesen, D1
Aldini, G; Angeli, A; Dallanoce, C; Fumagalli, L; Supuran, CT; Vistoli, G1
Liu, W; Liu, Z; Qi, F; Song, X; Xia, K; Zhao, M; Zhao, T; Zheng, Y1
Bellia, F; Bognanni, N; Vecchio, G1

Reviews

8 review(s) available for carcinine and carnosine

ArticleYear
Therapeutic uses of drug-carrier systems for imidazole-containing dipeptide compounds that act as pharmacological chaperones and have significant impact on the treatment of chronic diseases associated with increased oxidative stress and the formation of a
    Critical reviews in therapeutic drug carrier systems, 2010, Volume: 27, Issue:2

    Topics: Aging; Animals; Biomarkers; Carnosine; Chemistry, Pharmaceutical; Chronic Disease; Drug Carriers; Drug Compounding; Drug Design; Eye Diseases; Glycation End Products, Advanced; Humans; Lens, Crystalline; Lipid Peroxidation; Models, Molecular; Molecular Structure; Oxidative Stress; Skin; Skin Aging; Skin Diseases; Structure-Activity Relationship

2010
Designation of imidazole-containing dipeptides as pharmacological chaperones.
    Human & experimental toxicology, 2011, Volume: 30, Issue:7

    Topics: Carnosine; Cataract; Drug Carriers; Humans; Imidazoles; Lipid Peroxidation; Macular Degeneration; Molecular Chaperones; Oxidative Stress

2011
Biologic activities of molecular chaperones and pharmacologic chaperone imidazole-containing dipeptide-based compounds: natural skin care help and the ultimate challenge: implication for adaptive responses in the skin.
    American journal of therapeutics, 2012, Volume: 19, Issue:2

    Topics: Antioxidants; Carnosine; Free Radicals; Humans; Molecular Chaperones; Oxidative Stress; Skin Aging; Skin Diseases; Skin Physiological Phenomena

2012
Advanced drug delivery of N-acetylcarnosine (N-acetyl-beta-alanyl-L-histidine), carcinine (beta-alanylhistamine) and L-carnosine (beta-alanyl-L-histidine) in targeting peptide compounds as pharmacological chaperones for use in tissue engineering, human di
    Recent patents on drug delivery & formulation, 2010, Volume: 4, Issue:3

    Topics: Animals; Carnosine; Drug Delivery Systems; Heat-Shock Proteins; Humans; Molecular Chaperones; Patents as Topic; Protein Folding; Tissue Engineering

2010
Novel intraocular and systemic absorption drug delivery and efficacy of N-acetylcarnosine lubricant eye drops or carcinine biologics in pharmaceutical usage and therapeutic vision care.
    Fundamental & clinical pharmacology, 2012, Volume: 26, Issue:5

    Topics: Administration, Ophthalmic; Animals; Carnosine; Cataract; Chromatography, High Pressure Liquid; Clinical Trials, Phase II as Topic; Drug Delivery Systems; Eye Diseases; Humans; Prodrugs; Randomized Controlled Trials as Topic; Vitreoretinopathy, Proliferative

2012
Structural and functional properties, chaperone activity and posttranslational modifications of alpha-crystallin and its related subunits in the crystalline lens: N-acetylcarnosine, carnosine and carcinine act as alpha- crystallin/small heat shock protein
    Recent patents on drug delivery & formulation, 2012, Volume: 6, Issue:2

    Topics: Age Factors; alpha-Crystallins; Animals; Carnosine; Cataract; Drug Design; Humans; Lens, Crystalline; Molecular Chaperones; Oxidative Stress; Patents as Topic

2012
The detox strategy in smoking comprising nutraceutical formulas of non-hydrolyzed carnosine or carcinine used to protect human health.
    Human & experimental toxicology, 2014, Volume: 33, Issue:3

    Topics: Carnosine; Dietary Supplements; Free Radical Scavengers; Health; Humans; Nicotiana; Oxidative Stress; Pulmonary Disease, Chronic Obstructive; Smoke; Smoking; Telomere Shortening

2014
Novel neuroendocrine and metabolic mechanism provides the patented platform for important rejuvenation therapies: targeted therapy of telomere attrition and lifestyle changes of telomerase activity with the timing of neuron-specific imidazole-containing d
    Recent patents on endocrine, metabolic & immune drug discovery, 2014, Volume: 8, Issue:3

    Topics: Aging; Carnosine; Dipeptides; Humans; Imidazoles; Life Style; Molecular Targeted Therapy; Patents as Topic; Rejuvenation; Telomere Homeostasis; Telomere Shortening

2014

Trials

1 trial(s) available for carcinine and carnosine

ArticleYear
Skin beautification with oral non-hydrolized versions of carnosine and carcinine: Effective therapeutic management and cosmetic skincare solutions against oxidative glycation and free-radical production as a causal mechanism of diabetic complications and
    The Journal of dermatological treatment, 2012, Volume: 23, Issue:5

    Topics: Adolescent; Adult; Aged; Carnosine; Ceruloplasmin; Dermatologic Agents; Diabetes Complications; Double-Blind Method; Female; Free Radicals; Glycation End Products, Advanced; Humans; Lysine; Middle Aged; Oxidative Stress; Pyruvaldehyde; Schiff Bases; Skin Aging; Skin Diseases; Young Adult

2012

Other Studies

36 other study(ies) available for carcinine and carnosine

ArticleYear
Pharmacophore guided discovery of small-molecule interleukin 15 inhibitors.
    European journal of medicinal chemistry, 2017, Aug-18, Volume: 136

    Topics: Dose-Response Relationship, Drug; Humans; Interleukin-15; Molecular Structure; Small Molecule Libraries; Structure-Activity Relationship

2017
[Carcinine (beta-alanyl-histamine): rapid synthesis and action on vertebrate blood pressure].
    Archives internationales de physiologie et de biochimie, 1977, Volume: 85, Issue:2

    Topics: Animals; Blood Pressure; Carnosine; Dicyclohexylcarbodiimide; Dipeptides; Heart Rate; Rabbits; Rats; Species Specificity

1977
Effect of histamine antagonists on myocardial carcinine metabolism during compound 48/80-induced shock.
    The Journal of surgical research, 1990, Volume: 49, Issue:4

    Topics: Animals; Carnosine; Chromatography, High Pressure Liquid; Cimetidine; Diphenhydramine; Histamine; Histamine Antagonists; Histidine; Male; Methylhistamines; Myocardium; Oxamic Acid; p-Methoxy-N-methylphenethylamine; Rats; Rats, Inbred Strains; Receptors, Histamine H1; Receptors, Histamine H2; Shock

1990
Existence of carcinine, a histamine-related compound, in mammalian tissues.
    Life sciences, 1990, Volume: 47, Issue:17

    Topics: Animals; Carnosine; Female; Guinea Pigs; Histamine; Histidine; Humans; Intestines; Kidney; Liver; Male; Mice; Myocardium; Pituitary Gland; Rats; Rats, Inbred Strains

1990
Positive inotropic effect of carcinine in the isolated perfused guinea pig heart.
    Critical care medicine, 1990, Volume: 18, Issue:3

    Topics: Animals; Carnosine; Dipeptides; Dose-Response Relationship, Drug; Guinea Pigs; Heart; Myocardial Contraction; Stimulation, Chemical

1990
[Biosynthesis of carcinine (beta-alanyl-histamine) in vivo].
    Archives internationales de physiologie et de biochimie, 1985, Volume: 93, Issue:4

    Topics: Alanine; Animals; Brachyura; Carnosine; Dipeptides; Histidine; Time Factors

1985
[Beta-alanylation, a means for neutralization of histamine in the central nervous system of Carcinus maenas].
    Canadian journal of physiology and pharmacology, 1987, Volume: 65, Issue:9

    Topics: Alanine; Animals; beta-Alanine; Carnosine; Crustacea; Histamine; Muscles; Myocardium; Nervous System

1987
[Demonstration of carcinine synthetase, a new enzyme catalysing the metabolism of histamine in the central nervous system of Carcinus maenas].
    Journal of neurochemistry, 1987, Volume: 48, Issue:4

    Topics: Adenosine Triphosphate; Alanine; Animals; Brachyura; Carnosine; Dithiothreitol; Histamine; Histidine; Magnesium; Muscles; Myocardium; Nervous System; Peptide Synthases; Substrate Specificity; Tissue Distribution

1987
[Titration method for determination of carcinine (beta-alanyl-histamine). Application to the heart of Carcinus maenas (L.)].
    Archives internationales de physiologie et de biochimie, 1980, Volume: 88, Issue:3

    Topics: Animals; Brachyura; Carnosine; Chromatography, Ion Exchange; Dipeptides; Histamine; Hydrogen-Ion Concentration; Myocardium; Spectrophotometry

1980
[The effect of carnosine and carcinine on platelet function].
    Doklady Akademii nauk, 1994, Volume: 338, Issue:5

    Topics: Carnosine; Humans; Platelet Activation; Platelet Aggregation

1994
L-carnosine (beta-alanyl-L-histidine) and carcinine (beta-alanylhistamine) act as natural antioxidants with hydroxyl-radical-scavenging and lipid-peroxidase activities.
    The Biochemical journal, 1994, Dec-01, Volume: 304 ( Pt 2)

    Topics: Antioxidants; Ascorbic Acid; Carnosine; Edetic Acid; Ferrous Compounds; Free Radical Scavengers; Histamine; Histidine; Hydrogen Peroxide; Hydroxyl Radical; Kinetics; Linoleic Acid; Linoleic Acids; Lipid Peroxidation; Liposomes; Malondialdehyde; Phosphatidylcholines; Superoxides; Thiobarbituric Acid Reactive Substances

1994
[Lipoperoxidase activity of carnosine and carcinine].
    Doklady Akademii nauk, 1993, Volume: 333, Issue:1

    Topics: Antioxidants; Carnosine; Catalysis; Iron Chelating Agents; Lipid Peroxidation; Peroxidases

1993
[Relationship between the nature of N-acyl substituent, molecular conformation and antioxidative properties of carnosine, carcinine, and their structural analogs].
    Doklady Akademii nauk, 1996, Volume: 349, Issue:5

    Topics: Antioxidants; Carnosine; Histamine; Models, Molecular; Protein Conformation; Structure-Activity Relationship

1996
Hemodynamic effects of carcinine in the anesthetized, instrumented, open-chest rat.
    Critical care medicine, 1996, Volume: 24, Issue:12

    Topics: Anesthesia; Anesthetics, Dissociative; Animals; Carnosine; Dose-Response Relationship, Drug; Hemodynamics; Injections, Intravenous; Ketamine; Male; Rats; Rats, Sprague-Dawley

1996
Photoprotector and antioxidant properties of histamine-containing peptidomimetics in the photooxidation of glycyltryptophan.
    Biochemistry. Biokhimiia, 1998, Volume: 63, Issue:5

    Topics: Antioxidants; Carnosine; Dipeptides; Histamine; In Vitro Techniques; Kinetics; Luminescent Measurements; Models, Molecular; Molecular Conformation; Oxidation-Reduction; Photochemistry

1998
Synthesis of perfluoroalkylated beta-alanine and some peptide derivatives: an access to original surfactants.
    Amino acids, 1999, Volume: 16, Issue:3-4

    Topics: Acrylates; Blood Substitutes; Carnosine; Fluorocarbons; Peptides; Sodium Azide; Surface-Active Agents

1999
tan and ebony genes regulate a novel pathway for transmitter metabolism at fly photoreceptor terminals.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Dec-15, Volume: 22, Issue:24

    Topics: Animals; beta-Alanine; Carnosine; Chromosomal Proteins, Non-Histone; DNA-Binding Proteins; Dopamine; Drosophila melanogaster; Drosophila Proteins; Genes, Insect; Histamine; Microscopy, Fluorescence; Models, Biological; Mutation; Phenotype; Photoreceptor Cells, Invertebrate; Presynaptic Terminals; Signal Transduction; Synaptic Vesicles

2002
[Effect of alahistidine on brain histamine content and seizure development].
    Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2004, Volume: 33, Issue:3

    Topics: Animals; Brain Chemistry; Carnosine; Histamine; Male; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Receptors, Histamine H1; Seizures

2004
Pharmacological effects of carcinine on histaminergic neurons in the brain.
    British journal of pharmacology, 2004, Volume: 143, Issue:5

    Topics: Animals; Avoidance Learning; Brain; Carnosine; Convulsants; Dopamine; Histamine; Histidine Decarboxylase; In Vitro Techniques; Kindling, Neurologic; Mice; Mice, Inbred ICR; Motor Activity; Muscarinic Antagonists; Neurons; Pentylenetetrazole; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Scopolamine; Seizures; Serotonin

2004
Reinvestigation of the copper(II)-carcinine equilibrium system: "two-dimensional" EPR simulation and NMR relaxation studies for determining the formation constants and coordination modes.
    Journal of inorganic biochemistry, 2004, Volume: 98, Issue:12

    Topics: Carnosine; Copper; Electron Spin Resonance Spectroscopy; Hydrogen-Ion Concentration; Kinetics; Ligands; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Solutions; Superoxide Dismutase

2004
Biological activities of the natural imidazole-containing peptidomimetics n-acetylcarnosine, carcinine and L-carnosine in ophthalmic and skin care products.
    Life sciences, 2006, Apr-11, Volume: 78, Issue:20

    Topics: Aldehydes; Animals; Aqueous Humor; Carnosine; Chinchilla; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Imidazoles; Lipid Peroxidation; Male; Microsomes; Models, Molecular; Ophthalmic Solutions; Peroxides; Phospholipids; Rabbits; Skin Aging; Skin Care; Superoxide Dismutase; Ultraviolet Rays

2006
The role of carcinine in signaling at the Drosophila photoreceptor synapse.
    PLoS genetics, 2007, Volume: 3, Issue:12

    Topics: Animals; Animals, Genetically Modified; Base Sequence; Carnosine; DNA Primers; DNA-Binding Proteins; Drosophila melanogaster; Drosophila Proteins; Electroretinography; Genes, Insect; Histamine; Histamine H3 Antagonists; Models, Neurological; Mutation; Neuroglia; Neurons, Afferent; Phenotype; Photoreceptor Cells, Invertebrate; Piperidines; Plasma Membrane Neurotransmitter Transport Proteins; Signal Transduction; Synapses

2007
Alternative tasks of Drosophila tan in neurotransmitter recycling versus cuticle sclerotization disclosed by kinetic properties.
    The Journal of biological chemistry, 2010, Jul-02, Volume: 285, Issue:27

    Topics: Animals; Axons; beta-Alanine; Carnosine; Chromatography, Gel; Chromosomal Proteins, Non-Histone; Cysteine; Dimerization; DNA-Binding Proteins; Drosophila melanogaster; Drosophila Proteins; Escherichia coli; Gene Expression Regulation; Genes, Insect; Glycine; Hydrolases; Neurotransmitter Agents; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA; Signal Transduction

2010
The metabolism of histamine in the Drosophila optic lobe involves an ommatidial pathway: β-alanine recycles through the retina.
    The Journal of experimental biology, 2012, Apr-15, Volume: 215, Issue:Pt 8

    Topics: Animals; beta-Alanine; Biosynthetic Pathways; Carnosine; Drosophila melanogaster; Electroretinography; Head; Histamine; Mutation; Optic Lobe, Nonmammalian; Pigments, Biological; Retina; Tritium

2012
Carcinine has 4-hydroxynonenal scavenging property and neuroprotective effect in mouse retina.
    Investigative ophthalmology & visual science, 2012, Jun-20, Volume: 53, Issue:7

    Topics: Aldehydes; Animals; BALB 3T3 Cells; Carnosine; Chromatography, High Pressure Liquid; Electroretinography; Eye Proteins; Mass Spectrometry; Mice; Neuroprotective Agents; Oxidative Stress; Retina; Retinal Degeneration; Retinal Dehydrogenase

2012
Long-distance mechanism of neurotransmitter recycling mediated by glial network facilitates visual function in Drosophila.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Feb-18, Volume: 111, Issue:7

    Topics: Animals; beta-Alanine; Biological Transport; Carnosine; Connexins; Drosophila melanogaster; Drosophila Proteins; Electroretinography; Fluoroimmunoassay; Gene Knockdown Techniques; Histamine; Microscopy, Confocal; Microscopy, Electron, Transmission; Neuroglia; Neurotransmitter Agents; Photoreceptor Cells, Invertebrate; Retina; RNA Interference; Synaptic Transmission; Vision, Ocular

2014
Drosophila Ebony: a novel type of nonribosomal peptide synthetase related enzyme with unusually fast peptide bond formation kinetics.
    The FEBS journal, 2014, Volume: 281, Issue:22

    Topics: Animals; beta-Alanine; Carnosine; Catalytic Domain; DNA-Binding Proteins; Drosophila melanogaster; Drosophila Proteins; Kinetics; Peptide Synthases; Protein Binding; Sf9 Cells; Spodoptera

2014
The carcinine transporter CarT is required in Drosophila photoreceptor neurons to sustain histamine recycling.
    eLife, 2015, Dec-14, Volume: 4

    Topics: Animals; Carnosine; Drosophila; Gene Expression; Gene Knockout Techniques; Genetic Testing; Histamine; Nerve Tissue Proteins; Neuroglia; Photoreceptor Cells; RNA Interference

2015
Quantification of Histamine and Carcinine in Drosophila melanogaster Tissues.
    ACS chemical neuroscience, 2016, Mar-16, Volume: 7, Issue:3

    Topics: Animals; Animals, Genetically Modified; Carnosine; Drosophila melanogaster; Drosophila Proteins; Electrochemical Techniques; Electrophoresis, Capillary; Female; Histamine

2016
Drosophila Vision Depends on Carcinine Uptake by an Organic Cation Transporter.
    Cell reports, 2016, Mar-08, Volume: 14, Issue:9

    Topics: Amino Acid Sequence; Animals; Carnosine; Cation Transport Proteins; Cell Line; Drosophila melanogaster; Drosophila Proteins; Photoreceptor Cells, Invertebrate; Synaptic Transmission; Vision, Ocular

2016
Unusual tissue distribution of carcinin, an antibacterial crustin, in the crab, Carcinus maenas, reveals its multi-functionality.
    Developmental and comparative immunology, 2017, Volume: 76

    Topics: Ablation Techniques; Animal Shells; Animals; Anterior Eye Segment; Anti-Bacterial Agents; Brachyura; Carnosine; Cells, Cultured; Female; Gene Expression; Hemocytes; Hemolymph; Immunity, Innate; Oogenesis; Ovary; Regeneration; Wound Healing

2017
Carnosine and Carcinine Derivatives Rapidly React with Hypochlorous Acid to Form Chloramines and Dichloramines.
    Chemical research in toxicology, 2019, 03-18, Volume: 32, Issue:3

    Topics: Carnosine; Chloramines; Hypochlorous Acid; Kinetics; Molecular Structure

2019
The glial sodium-potassium-2-chloride cotransporter is required for synaptic transmission in the Drosophila visual system.
    Scientific reports, 2019, 02-21, Volume: 9, Issue:1

    Topics: Animals; Carnosine; Drosophila; Drosophila Proteins; Histamine; Mutation; Neuroglia; Phenotype; Photoreceptor Cells, Invertebrate; Protein Serine-Threonine Kinases; Sodium-Potassium-Chloride Symporters; Synaptic Transmission

2019
Activation Effects of Carnosine- and Histidine-Containing Dipeptides on Human Carbonic Anhydrases: A Comprehensive Study.
    International journal of molecular sciences, 2020, Mar-04, Volume: 21, Issue:5

    Topics: Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase IX; Carbonic Anhydrase V; Carbonic Anhydrases; Carnosine; Chelating Agents; Dipeptides; Histidine; Humans; Kinetics; Models, Molecular; Protein Domains; Protons; Software

2020
Whole-cell biotransformation for large scale production of carcinine in Escherichia coli.
    Journal of biotechnology, 2022, Aug-10, Volume: 354

    Topics: beta-Alanine; Biotransformation; Carnosine; Escherichia coli; Glycine; Histamine; Metabolic Engineering

2022
Cyclodextrin Polymers Functionalized with Histidine and Carcinine as Chelating Therapeutics for Copper Dyshomeostasis.
    ChemMedChem, 2023, Jul-03, Volume: 18, Issue:13

    Topics: Antioxidants; Carnosine; Chelating Agents; Copper; Cyclodextrins; Histidine

2023