carboxymethyl-beta-cyclodextrin has been researched along with 2-phenylsuccinate* in 1 studies
1 other study(ies) available for carboxymethyl-beta-cyclodextrin and 2-phenylsuccinate
| Article | Year |
|---|---|
Enantioselective extraction of phenylsuccinic acid in aqueous two-phase systems based on acetone and β-cyclodextrin derivative: Modeling and optimization through response surface methodology.
A novel aqueous two-phase system (ATPS) composed of β-cyclodextrin (β-CD) derivative and acetone was developed for enantioselective extraction of racemic phenylsuccinic acid (PSA). Binodal curves, tie-lines, and critical points for the investigated ATPS were determined and the experimental tie-lines data were successfully correlated by Othmer-Tobias, Bancroft, and Setschenow-type equations. ATPS containing sulfobutyl ether-β-CD (SBE-β-CD) exhibited better enantioselectivity than that using carboxymethyl-β-CD (CM-β-CD). To optimize enantioselective partitioning conditions of PSA in acetone/SBE-β-CD ATPS, three factors (PSA concentration, pH, and equilibrium temperature) were analyzed by using central composite design in response surface methodology. The calculated equilibrium constants of inclusion complexation are 1638.64M Topics: Acetone; Algorithms; beta-Cyclodextrins; Hydrogen-Ion Concentration; Models, Chemical; Stereoisomerism; Succinates | 2016 |