carboxyebselen has been researched along with ebselen in 6 studies
Studies (carboxyebselen) | Trials (carboxyebselen) | Recent Studies (post-2010) (carboxyebselen) | Studies (ebselen) | Trials (ebselen) | Recent Studies (post-2010) (ebselen) |
---|---|---|---|---|---|
6 | 0 | 5 | 839 | 9 | 366 |
Protein | Taxonomy | carboxyebselen (IC50) | ebselen (IC50) |
---|---|---|---|
RNA polymerase beta subunit (EC 2.7.7.6), partial | Escherichia coli | 11.6872 | |
Arrestin, beta 1 | Homo sapiens (human) | 1.524 | |
MPI protein | Homo sapiens (human) | 0.19 | |
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase | Plasmodium berghei | 15.0867 | |
TPA: protein transporter TIM10 | Saccharomyces cerevisiae S288C | 5.29 | |
TPA: protein transporter TIM23 | Saccharomyces cerevisiae S288C | 0.88 | |
hexokinase | Trypanosoma brucei brucei TREU927 | 0.9009 | |
Spike glycoprotein | Betacoronavirus England 1 | 0.67 | |
Replicase polyprotein 1ab | Betacoronavirus England 1 | 0.67 | |
neutrophil cytosol factor 1 | Homo sapiens (human) | 0.39 | |
phosphomannomutase 2 | Homo sapiens (human) | 0.672 | |
perilipin-5 | Homo sapiens (human) | 1.101 | |
glucose-6-phosphate 1-dehydrogenase isoform b | Homo sapiens (human) | 13.2 | |
phosphoethanolamine/phosphocholine phosphatase isoform 1 | Homo sapiens (human) | 0.111 | |
perilipin-1 | Homo sapiens (human) | 3.41 | |
eukaryotic translation initiation factor 4 gamma 1 isoform 4 | Homo sapiens (human) | 1.15 | |
eukaryotic translation initiation factor 4E isoform 1 | Mus musculus (house mouse) | 1.15 | |
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a | Homo sapiens (human) | 2.2555 | |
Sulfhydryl oxidase 1 | Homo sapiens (human) | 5.4 | |
Transmembrane protease serine 2 | Homo sapiens (human) | 0.67 | |
Prostaglandin G/H synthase 1 | Bos taurus (cattle) | 2.1 | |
Gamma-butyrobetaine dioxygenase | Homo sapiens (human) | 0.742 | |
Bile salt export pump | Homo sapiens (human) | 10 | |
Procathepsin L | Homo sapiens (human) | 0.67 | |
Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | 0.67 | |
Replicase polyprotein 1ab | Human coronavirus 229E | 0.67 | |
Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | 0.62 | |
Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | 0.7928 | |
Macrophage migration inhibitory factor | Homo sapiens (human) | 2.4 | |
Insulin-degrading enzyme | Homo sapiens (human) | 0.028 | |
Urease subunit alpha | Helicobacter pylori 26695 | 3.745 | |
Toxin B | Clostridioides difficile | 0.0172 | |
Caspase-1 | Homo sapiens (human) | 4.04 | |
Bifunctional epoxide hydrolase 2 | Homo sapiens (human) | 0.7575 | |
Methionine aminopeptidase 2 | Homo sapiens (human) | 2.43 | |
Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | 0.67 | |
Urease subunit beta | Helicobacter pylori 26695 | 3.745 | |
UDP-glucose 4-epimerase | Homo sapiens (human) | 0.014 | |
Structural capsid protein | Human immunodeficiency virus 1 | 0.0467 | |
Histone-lysine N-methyltransferase EHMT2 | Homo sapiens (human) | 0.4 | |
Angiotensin-converting enzyme 2 | Homo sapiens (human) | 0.67 | |
Histone-lysine N-methyltransferase EHMT1 | Homo sapiens (human) | 0.73 | |
Histone deacetylase 6 | Homo sapiens (human) | 4.05 | |
Histone deacetylase 9 | Homo sapiens (human) | 3.7 | |
Histone deacetylase 5 | Homo sapiens (human) | 3.4 | |
large T antigen | Betapolyomavirus macacae | 13.91 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (16.67) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 3 (50.00) | 24.3611 |
2020's | 2 (33.33) | 2.80 |
Authors | Studies |
---|---|
Anayee, M; Golden, JE; Gordhan, HM; Hackler, AL; Morris, JC; Patrick, SL; Swasy, MI; Whitehead, DC | 1 |
Chan, EWC; Chan, KF; Chan, TH; Chen, S; Cheng, Q; Gao, W; Jin, WB; Leung, YC; Qi, XL; Wong, KY; Xu, C; Zheng, Z | 1 |
Chen, J; Gao, K; Huang, F; Tepe, JJ; Wang, R; Wei, GW | 1 |
Cao, H; Chen, H; Han, X; Huang, Y; Liu, J; Peng, C; Rao, L; Ren, Y; Sheng, C; Su, C; Tu, J; Wan, C; Wan, J; Wen, W | 1 |
Gryglewski, RJ; Hatchett, RJ; MÅ‚ochowski, J; Radziszewski, W; Zembowicz, A | 1 |
Ashe, AJ; Cai, W; Meyerhoff, ME; Wu, J; Xi, C | 1 |
6 other study(ies) available for carboxyebselen and ebselen
Article | Year |
---|---|
Evaluation of substituted ebselen derivatives as potential trypanocidal agents.
Topics: Antiprotozoal Agents; Azoles; Dose-Response Relationship, Drug; Isoindoles; Molecular Structure; Organoselenium Compounds; Parasitic Sensitivity Tests; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei | 2017 |
Investigation of synergistic antimicrobial effects of the drug combinations of meropenem and 1,2-benzisoselenazol-3(2H)-one derivatives on carbapenem-resistant Enterobacteriaceae producing NDM-1.
Topics: Anti-Bacterial Agents; beta-Lactamases; Carbapenem-Resistant Enterobacteriaceae; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; HeLa Cells; Humans; Meropenem; Molecular Structure; Organoselenium Compounds; Structure-Activity Relationship; Thienamycins | 2018 |
Perspectives on SARS-CoV-2 Main Protease Inhibitors.
Topics: Antiviral Agents; Coronavirus 3C Proteases; Humans; Protease Inhibitors | 2021 |
Structure-Guided Discovery of the Novel Covalent Allosteric Site and Covalent Inhibitors of Fructose-1,6-Bisphosphate Aldolase to Overcome the Azole Resistance of
Topics: Allosteric Site; Antifungal Agents; Azoles; Biofilms; Candida albicans; Candida parapsilosis; Drug Resistance, Fungal; Enzyme Inhibitors; Fructose-Bisphosphate Aldolase; Fungal Proteins; Microbial Sensitivity Tests; Molecular Structure; Protein Binding; Structure-Activity Relationship | 2022 |
Carboxyebselen a potent and selective inhibitor of endothelial nitric oxide synthase.
Topics: Acetylcholine; Acetylcysteine; Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Azoles; Cattle; Cerebellum; Endothelium, Vascular; Female; Glutathione; Glutathione Peroxidase; In Vitro Techniques; Isoindoles; Male; Mice; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Organoselenium Compounds; Rabbits; Spleen; Sulfhydryl Compounds; Swine | 1994 |
Carboxyl-ebselen-based layer-by-layer films as potential antithrombotic and antimicrobial coatings.
Topics: Animals; Anti-Infective Agents; Antithrombins; Azoles; Catalysis; Coated Materials, Biocompatible; Cross-Linking Reagents; Escherichia coli; Free Radical Scavengers; Isoindoles; Microbial Sensitivity Tests; Microbial Viability; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Nitric Oxide; Organoselenium Compounds; Polyethyleneimine; S-Nitrosothiols; Selenium; Sheep; Spectrophotometry, Ultraviolet; Superoxides | 2011 |