Compounds > carboxyebselen
Page last updated: 2024-09-05

carboxyebselen and 2-phenyl-1,2-benzisothiazol-3-(2h)-one

carboxyebselen has been researched along with 2-phenyl-1,2-benzisothiazol-3-(2h)-one in 3 studies

Compound Research Comparison

Studies
(carboxyebselen)		Trials
(carboxyebselen)		Recent Studies (post-2010)
(carboxyebselen)		Studies
(2-phenyl-1,2-benzisothiazol-3-(2h)-one)		Trials
(2-phenyl-1,2-benzisothiazol-3-(2h)-one)		Recent Studies (post-2010) (2-phenyl-1,2-benzisothiazol-3-(2h)-one)
60523011

Protein Interaction Comparison

ProteinTaxonomycarboxyebselen (IC50)2-phenyl-1,2-benzisothiazol-3-(2h)-one (IC50)
MPI proteinHomo sapiens (human)13.825
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonasePlasmodium berghei6.26
hexokinaseTrypanosoma brucei brucei TREU9273.9563
caspase recruitment domain family, member 15Homo sapiens (human)3.999
phosphomannomutase 2Homo sapiens (human)36.9
glucose-6-phosphate 1-dehydrogenase isoform bHomo sapiens (human)8.87
phosphoethanolamine/phosphocholine phosphatase isoform 1Homo sapiens (human)0.941
receptor-interacting serine/threonine-protein kinase 2 isoform 1Homo sapiens (human)3.999
eukaryotic translation initiation factor 4 gamma 1 isoform 4Homo sapiens (human)20.0657
eukaryotic translation initiation factor 4E isoform 1Mus musculus (house mouse)20.0657
DNA dC->dU-editing enzyme APOBEC-3G isoform 1Homo sapiens (human)6.4
Neutrophil elastaseHomo sapiens (human)1.1107
Replicase polyprotein 1abSevere acute respiratory syndrome-related coronavirus0.49
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 20.49
Mannose-6-phosphate isomeraseHomo sapiens (human)6.4
Caspase-3Homo sapiens (human)0.5328
Phosphoethanolamine/phosphocholine phosphataseHomo sapiens (human)0.94

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's2 (66.67)2.80

Authors

AuthorsStudies
Anayee, M; Golden, JE; Gordhan, HM; Hackler, AL; Morris, JC; Patrick, SL; Swasy, MI; Whitehead, DC1
Chen, J; Gao, K; Huang, F; Tepe, JJ; Wang, R; Wei, GW1
Cao, H; Chen, H; Han, X; Huang, Y; Liu, J; Peng, C; Rao, L; Ren, Y; Sheng, C; Su, C; Tu, J; Wan, C; Wan, J; Wen, W1

Other Studies

3 other study(ies) available for carboxyebselen and 2-phenyl-1,2-benzisothiazol-3-(2h)-one

ArticleYear
Evaluation of substituted ebselen derivatives as potential trypanocidal agents.
    Bioorganic & medicinal chemistry letters, 2017, 02-01, Volume: 27, Issue:3

    Topics: Antiprotozoal Agents; Azoles; Dose-Response Relationship, Drug; Isoindoles; Molecular Structure; Organoselenium Compounds; Parasitic Sensitivity Tests; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei

2017
Perspectives on SARS-CoV-2 Main Protease Inhibitors.
    Journal of medicinal chemistry, 2021, 12-09, Volume: 64, Issue:23

    Topics: Antiviral Agents; Coronavirus 3C Proteases; Humans; Protease Inhibitors

2021
Structure-Guided Discovery of the Novel Covalent Allosteric Site and Covalent Inhibitors of Fructose-1,6-Bisphosphate Aldolase to Overcome the Azole Resistance of
    Journal of medicinal chemistry, 2022, 02-10, Volume: 65, Issue:3

    Topics: Allosteric Site; Antifungal Agents; Azoles; Biofilms; Candida albicans; Candida parapsilosis; Drug Resistance, Fungal; Enzyme Inhibitors; Fructose-Bisphosphate Aldolase; Fungal Proteins; Microbial Sensitivity Tests; Molecular Structure; Protein Binding; Structure-Activity Relationship

2022