carbonyl cyanide m-chlorophenyl hydrazone and verapamil

carbonyl cyanide m-chlorophenyl hydrazone has been researched along with verapamil in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19902 (6.06)18.7374
1990's9 (27.27)18.2507
2000's2 (6.06)29.6817
2010's18 (54.55)24.3611
2020's2 (6.06)2.80

Authors

AuthorsStudies
Ghosh, I; Manoharlal, R; Prakash, O; Prasad, R; Puri, N; Sharma, M1
Bucar, F; Gröblacher, B; Kunert, O1
Gupta, S; Jachak, SM; Kumari, N; Nandanwar, H; Pahwa, S; Roy, SK1
Alam, MZ; Bruhn, DF; Feng, L; Hurdle, JG; Lee, RB; Lee, RE; Maddox, MM; Narula, G; Sandhaus, S; Simmons, CJ; Sun, D; Tse-Dinh, YC; Tsutsumi, LS; Wu, X1
Bassetto, M; Brancale, A; Ferla, S; Kandil, S; McGuigan, C; Pertusati, F; Westwell, AD2
Handzlik, J; Jastrzębska-Więsek, M; Kieć-Kononowicz, K; Kucwaj-Brysz, K; Latacz, G; Lubelska, A; Partyka, A; Wesołowska, A1
Abouf, M; Abutaleb, NS; Chen, L; Elsebaei, MM; Ghiaty, A; Hegazy, YA; Malwal, SR; Mayhoub, AS; Mohammad, H; Oldfield, E; Seleem, MN; Zhang, J1
Deka Boruah, HP; Gogoi, P; Manna, P; Neog, K; Sarma, S; Sen, T; Singh, AK1
Hagenow, S; Karcz, T; Kieć-Kononowicz, K; Kotańska, M; Kuder, KJ; Latacz, G; Lubelska, A; Mogilski, S; Siwek, A; Sobolewski, M; Stark, H; Szczepańska, K1
Bora, A; Deka, B; Devi, MV; Dihingia, A; Pahari, P; Sarma, S; Sen, T; Singh, AK; Suri, M1
Prasad, KR; Rosoff, PM1
Henderson, GB1
Kasai, M; Muto, S1
Duddy, SK; Kass, GE; Orrenius, S1
Auld, AM; Barritt, GJ; Bruening, M; Shepherd, M1
Schoff, PK1
Deshpande, S; Hall, JC1
Futai, M; Manabe, T; Moriyama, Y; Tashiro, Y; Yoshimori, T1
Castoldi, AF; Costa, LG; Manzo, L; Tan, XX; Tang, C1
Banerjee, SK; Bhatt, K; Chakraborti, PK; Misra, P; Rana, S1
Chakrabarti, P; Choudhuri, BS; Sen, S1
Bai, J; Goh, BC; Lai, L; Tan, TM; Yeo, HC1
Amaral, L; Couto, I; Kern, WV; Rodrigues, L; Sampaio, D; Vavra, M; Viveiros, M; Wagner, D1
Almeida da Silva, PE; Ramos, DF1
Balganesh, M; Kuruppath, S; Marcel, N; Nair, A; Sharma, S; Sharma, U1
Guo, N; Jin, J; Li, L; Li, Y; Liang, JC; Liu, MY; Sheng, H; Wang, XL; Wu, XP; Yu, L; Zhang, JY1
Chauhan, DS; Chauhan, V; Gupta, K; Jadaun, GP; Katoch, VM; Mishra, R; Nair, S; Sharma, VD; Singh, M; Srivastava, K; Venkatesan, K1
Alfonso, S; Battilocchio, C; Biava, M; Botta, M; Buroni, S; Canseco, JO; De Logu, A; De Rossi, E; Ioerger, TR; Javid, B; La Rosa, V; Manetti, F; Pasca, MR; Poce, G; Porretta, GC; Raju, RM; Rubin, EJ; Sacchettini, JC; Sorrentino, F1
Papakrivos, J; Sá, JM; Wellems, TE1
Guo, Q; Jiang, Y; Li, C; Li, G; Lu, J; Qiu, Y; Wan, K; Wei, J; Zhang, J; Zhao, LL; Zhao, X1
Chien, JY; Hsueh, PR; Yu, CJ1
Coban, AY; Durupınar, B; Valıyeva, G1

Other Studies

33 other study(ies) available for carbonyl cyanide m-chlorophenyl hydrazone and verapamil

ArticleYear
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:11

    Topics: Candida albicans; Membrane Transport Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity

2010
Compounds of Alpinia katsumadai as potential efflux inhibitors in Mycobacterium smegmatis.
    Bioorganic & medicinal chemistry, 2012, Apr-15, Volume: 20, Issue:8

    Topics: Alpinia; Antibiotics, Antitubercular; Antitubercular Agents; Diarylheptanoids; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium smegmatis; Plant Extracts; Seeds

2012
7-Hydroxy-(E)-3-phenylmethylene-chroman-4-one analogues as efflux pump inhibitors against Mycobacterium smegmatis mc² 155.
    European journal of medicinal chemistry, 2013, Volume: 66

    Topics: Anti-Bacterial Agents; Chromans; Chromones; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Microbial Sensitivity Tests; Mycobacterium smegmatis; Structure-Activity Relationship

2013
Synthesis, structure-activity relationship studies, and antibacterial evaluation of 4-chromanones and chalcones, as well as olympicin A and derivatives.
    Journal of medicinal chemistry, 2014, Oct-23, Volume: 57, Issue:20

    Topics: Animals; Anti-Bacterial Agents; Chalcones; Chemistry Techniques, Synthetic; Chlorocebus aethiops; Chromones; DNA Gyrase; DNA Topoisomerase IV; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Phloroglucinol; Structure-Activity Relationship; Topoisomerase II Inhibitors; Vero Cells

2014
Design and synthesis of novel bicalutamide and enzalutamide derivatives as antiproliferative agents for the treatment of prostate cancer.
    European journal of medicinal chemistry, 2016, Aug-08, Volume: 118

    Topics: Anilides; Antineoplastic Agents; Benzamides; Caco-2 Cells; Cell Line, Tumor; Cell Proliferation; Chemistry Techniques, Synthetic; Drug Design; Drug Resistance, Neoplasm; Humans; Male; Microsomes, Liver; Molecular Docking Simulation; Molecular Dynamics Simulation; Nitriles; Permeability; Phenylthiohydantoin; Prostatic Neoplasms; Protein Conformation; Receptors, Androgen; Tosyl Compounds

2016
Rational design and synthesis of novel anti-prostate cancer agents bearing a 3,5-bis-trifluoromethylphenyl moiety.
    Bioorganic & medicinal chemistry letters, 2016, 08-01, Volume: 26, Issue:15

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Male; Molecular Docking Simulation; Molecular Structure; Prostatic Neoplasms; Structure-Activity Relationship; Xylenes

2016
MF-8, a novel promising arylpiperazine-hydantoin based 5-HT
    Bioorganic & medicinal chemistry letters, 2018, 03-01, Volume: 28, Issue:5

    Topics: Dose-Response Relationship, Drug; Humans; Hydantoins; Molecular Structure; Piperazines; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship

2018
Alkynyl-containing phenylthiazoles: Systemically active antibacterial agents effective against methicillin-resistant Staphylococcus aureus (MRSA).
    European journal of medicinal chemistry, 2018, Mar-25, Volume: 148

    Topics: Alkynes; Animals; Anti-Bacterial Agents; Half-Life; Methicillin-Resistant Staphylococcus aureus; Mice; Microsomes, Liver; Staphylococcal Infections; Thiazoles

2018
Efflux pump inhibition by 11H-pyrido[2,1-b]quinazolin-11-one analogues in mycobacteria.
    Bioorganic & medicinal chemistry, 2018, 09-15, Volume: 26, Issue:17

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Binding Sites; Biological Transport; Ethidium; Microbial Sensitivity Tests; Molecular Docking Simulation; Mycobacterium smegmatis; Mycobacterium tuberculosis; Norfloxacin; Quinazolines

2018
Optimization and preclinical evaluation of novel histamine H
    Bioorganic & medicinal chemistry, 2018, 12-15, Volume: 26, Issue:23-24

    Topics: Animals; Antineoplastic Agents; Body Weight; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Hep G2 Cells; Histamine H3 Antagonists; Humans; Ligands; Male; Mice; Models, Molecular; Molecular Structure; Piperazine; Rats; Receptors, Histamine H3; Structure-Activity Relationship

2018
Potentiating the intracellular killing of Staphylococcus aureus by dihydroquinazoline analogues as NorA efflux pump inhibitor.
    Bioorganic & medicinal chemistry, 2022, 01-15, Volume: 54

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Cell Survival; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Molecular Structure; Multidrug Resistance-Associated Proteins; Quinazolines; Staphylococcus aureus; Structure-Activity Relationship; THP-1 Cells

2022
Characterization of the energy-dependent, mating factor-activated Ca2+ influx in Saccharomyces cerevisiae.
    Cell calcium, 1992, Volume: 13, Issue:10

    Topics: 2,4-Dinitrophenol; Biological Transport, Active; Calcium; Calcium Channels; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cations; CDC28 Protein Kinase, S cerevisiae; Cell Cycle Proteins; Cell Differentiation; Dinitrophenols; Fungal Proteins; GTP-Binding Proteins; Interphase; Ion Channel Gating; Mating Factor; Membrane Potentials; Nifedipine; Peptides; Protein Kinases; Protein Serine-Threonine Kinases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction; Valinomycin; Verapamil

1992
Separation and inhibitor specificity of a second unidirectional efflux route for methotrexate in L1210 cells.
    Biochimica et biophysica acta, 1992, Oct-05, Volume: 1110, Issue:2

    Topics: Adenosine Triphosphate; Animals; Biological Transport; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Leukemia L1210; Methotrexate; Mice; Probenecid; Prostaglandins A; Quinidine; Reserpine; Sulfobromophthalein; Tumor Cells, Cultured; Verapamil; Vincristine

1992
Ca2+ pump and Ca2+/H+ antiporter in plasma membrane vesicles isolated by aqueous two-phase partitioning from corn leaves.
    The Journal of membrane biology, 1990, Volume: 114, Issue:2

    Topics: Adenosine Triphosphate; Antiporters; Biological Transport, Active; Calcium Channels; Calcium-Binding Proteins; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cation Transport Proteins; Cell Membrane; Hydrogen-Ion Concentration; Lanthanum; Magnesium; Protons; Salts; Vanadates; Verapamil; Zea mays

1990
Ca2(+)-mobilizing hormones stimulate Ca2+ efflux from hepatocytes.
    The Journal of biological chemistry, 1989, Dec-15, Volume: 264, Issue:35

    Topics: Animals; Benzofurans; Bucladesine; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cells, Cultured; Cytosol; Dibutyryl Cyclic GMP; Fluorescent Dyes; Fura-2; Hydroquinones; Imidazoles; Kinetics; Liver; Nifedipine; Pertussis Toxin; Rats; Tetradecanoylphorbol Acetate; Vasopressins; Verapamil; Virulence Factors, Bordetella

1989
Effects of energy deprivation and hydrogen peroxide on contraction and myoplasmic free calcium concentrations in isolated myocardial muscle cells.
    Biochemical medicine and metabolic biology, 1987, Volume: 38, Issue:2

    Topics: Adenosine Triphosphate; Animals; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Electric Stimulation; Energy Metabolism; Hydrogen Peroxide; In Vitro Techniques; Myocardial Contraction; Myocardium; Rats; Verapamil

1987
Mitochondrial calcium uptake stimulated by Cibacron blue F3GA in bovine sperm.
    Archives of biochemistry and biophysics, 1995, Apr-20, Volume: 318, Issue:2

    Topics: Adenosine Triphosphate; Animals; Biological Transport; Calcium; Calcium Channel Blockers; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cations, Divalent; Cattle; Diltiazem; Glucose; Kinetics; Male; Metals; Mitochondria; Nifedipine; Oligomycins; Protein Synthesis Inhibitors; Rotenone; Ruthenium Red; Spermatozoa; Triazines; Verapamil

1995
Comparison of flash-induced light-scattering transients and proton efflux from auxinic-herbicide resistant and susceptible wild mustard protoplasts: a possible role for calcium in mediating auxinic herbicide resistance.
    Biochimica et biophysica acta, 1995, May-11, Volume: 1244, Issue:1

    Topics: Acridine Orange; Adenosine Triphosphate; Calcimycin; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Drug Resistance; Hydrogen-Ion Concentration; In Vitro Techniques; Indoleacetic Acids; Light; Mustard Plant; Picloram; Plants, Medicinal; Scattering, Radiation; Verapamil

1995
ATP-dependent uptake of anti-neoplastic agents by acidic organelles.
    Journal of biochemistry, 1994, Volume: 115, Issue:2

    Topics: Adenosine Triphosphate; Ammonium Chloride; Animals; Antineoplastic Agents; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cattle; Cells, Cultured; Chromaffin Granules; Daunorubicin; Drug Resistance; Hydrogen-Ion Concentration; Mice; Nigericin; Organelles; Proteolipids; Proton-Translocating ATPases; Quinidine; Reserpine; Valinomycin; Vanadates; Verapamil

1994
Effects of inorganic and organic mercury on intracellular calcium levels in rat T lymphocytes.
    Journal of toxicology and environmental health, 1993, Volume: 38, Issue:2

    Topics: Animals; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Membrane; Cytoplasm; Drug Interactions; Lymphocyte Activation; Male; Mercuric Chloride; Methylmercury Compounds; Rats; Rats, Sprague-Dawley; T-Lymphocytes; Verapamil

1993
Involvement of an efflux system in mediating high level of fluoroquinolone resistance in Mycobacterium smegmatis.
    Biochemical and biophysical research communications, 1996, Sep-13, Volume: 226, Issue:2

    Topics: Amino Acid Sequence; Anti-Infective Agents; Base Sequence; Carbonyl Cyanide m-Chlorophenyl Hydrazone; DNA Gyrase; DNA Topoisomerases, Type II; DNA, Bacterial; Drug Resistance, Microbial; Fluoroquinolones; Molecular Sequence Data; Mutation; Mycobacterium; Verapamil

1996
Isoniazid accumulation in Mycobacterium smegmatis is modulated by proton motive force-driven and ATP-dependent extrusion systems.
    Biochemical and biophysical research communications, 1999, Mar-24, Volume: 256, Issue:3

    Topics: Adenosine Triphosphate; Antitubercular Agents; Biological Transport, Active; Calcium Channel Blockers; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Diltiazem; Drug Resistance, Microbial; Hydrogen-Ion Concentration; Ionophores; Isoniazid; Mycobacterium smegmatis; Nifedipine; Nigericin; Proton-Motive Force; Reserpine; Uncoupling Agents; Valinomycin; Vanadates; Verapamil

1999
Multidrug resistance protein 4 (MRP4/ABCC4) mediates efflux of bimane-glutathione.
    The international journal of biochemistry & cell biology, 2004, Volume: 36, Issue:2

    Topics: Adenosine Triphosphate; Anions; Antimetabolites, Antineoplastic; Benzbromarone; Biological Transport; Biological Transport, Active; Bridged Bicyclo Compounds; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Line; Cyclic AMP; Cyclic GMP; Cyclooxygenase Inhibitors; Dinitrochlorobenzene; Drug Resistance; Estradiol; Glutathione; Humans; Indomethacin; Methotrexate; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Oxygen; Phosphorylation; Thioguanine; Time Factors; Transfection; Verapamil

2004
Thioridazine and chlorpromazine inhibition of ethidium bromide efflux in Mycobacterium avium and Mycobacterium smegmatis.
    The Journal of antimicrobial chemotherapy, 2008, Volume: 61, Issue:5

    Topics: Anti-Bacterial Agents; Automation; Biological Transport, Active; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Chlorpromazine; Ethidium; Fluorometry; Membrane Transport Proteins; Mycobacterium avium; Mycobacterium smegmatis; Thioridazine; Time Factors; Verapamil

2008
Antimycobacterial activity of usnic acid against resistant and susceptible strains of Mycobacterium tuberculosis and non-tuberculous mycobacteria.
    Pharmaceutical biology, 2010, Volume: 48, Issue:3

    Topics: Anti-Bacterial Agents; Benzofurans; Calcium Channel Blockers; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Drug Evaluation, Preclinical; Drug Resistance, Bacterial; Ionophores; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nontuberculous Mycobacteria; Tuberculosis, Multidrug-Resistant; Verapamil

2010
Rv1218c, an ABC transporter of Mycobacterium tuberculosis with implications in drug discovery.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:12

    Topics: Antitubercular Agents; ATP-Binding Cassette Transporters; Bacterial Proteins; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Drug Discovery; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazolones; Reserpine; Verapamil

2010
Farnesol, a potential efflux pump inhibitor in Mycobacterium smegmatis.
    Molecules (Basel, Switzerland), 2010, Oct-29, Volume: 15, Issue:11

    Topics: Antitubercular Agents; Bacterial Proteins; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Chlorpromazine; Farnesol; Membrane Transport Proteins; Microbial Sensitivity Tests; Mycobacterium smegmatis; Nitriles; Reserpine; Verapamil

2010
Effect of efflux pump inhibitors on drug susceptibility of ofloxacin resistant Mycobacterium tuberculosis isolates.
    The Indian journal of medical research, 2011, Volume: 133

    Topics: 2,4-Dinitrophenol; ATP-Binding Cassette Transporters; Bacterial Proteins; Base Sequence; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Computational Biology; DNA Gyrase; DNA Primers; Drug Resistance, Bacterial; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Mycobacterium tuberculosis; Ofloxacin; Polymerase Chain Reaction; Sequence Alignment; Sequence Analysis, DNA; Species Specificity; Verapamil

2011
MmpL3 is the cellular target of the antitubercular pyrrole derivative BM212.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:1

    Topics: Animals; Antitubercular Agents; Carbon Radioisotopes; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cattle; DNA Mutational Analysis; Drug Resistance, Multiple, Bacterial; Genome, Bacterial; Genomic Library; Humans; Membrane Transport Proteins; Microbial Sensitivity Tests; Mutation; Mycobacterium bovis; Mycobacterium Infections, Nontuberculous; Mycobacterium smegmatis; Mycobacterium tuberculosis; Piperazines; Pyrroles; Reserpine; Verapamil

2012
Functional characterization of the Plasmodium falciparum chloroquine-resistance transporter (PfCRT) in transformed Dictyostelium discoideum vesicles.
    PloS one, 2012, Volume: 7, Issue:6

    Topics: Adenosine Triphosphate; Ammonia; Animals; Antimalarials; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Line, Transformed; Chloroquine; Cytoplasmic Vesicles; Dictyostelium; Hydrogen-Ion Concentration; Ionophores; Macrolides; Membrane Potentials; Membrane Transport Proteins; Phenotype; Plasmodium falciparum; Potassium; Protozoan Proteins; Valinomycin; Verapamil

2012
Antimycobacterial activity of five efflux pump inhibitors against Mycobacterium tuberculosis clinical isolates.
    The Journal of antibiotics, 2016, Volume: 69, Issue:3

    Topics: Adult; Antitubercular Agents; Carbonyl Cyanide m-Chlorophenyl Hydrazone; China; Chlorpromazine; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Reserpine; Thioridazine; Tuberculosis, Pulmonary; Verapamil

2016
High incidence of fluoroquinolone resistance and effect of efflux pump inhibitors on moxifloxacin resistance among Mycobacterium tuberculosis isolates causing urinary tract infection in Taiwan.
    International journal of antimicrobial agents, 2017, Volume: 50, Issue:3

    Topics: Anti-Bacterial Agents; Biological Transport, Active; Carbonyl Cyanide m-Chlorophenyl Hydrazone; DNA Gyrase; Drug Resistance, Bacterial; Enzyme Inhibitors; Fluoroquinolones; Humans; Incidence; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Prevalence; Reserpine; Taiwan; Tuberculosis, Urogenital; Verapamil

2017
Efflux pump effects on
    Journal of chemotherapy (Florence, Italy), 2023, Volume: 35, Issue:7

    Topics: Anti-Bacterial Agents; Antitubercular Agents; Bacterial Proteins; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Drug Resistance; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Reserpine; Verapamil

2023