Page last updated: 2024-08-17

carbon tetrachloride and transforming growth factor beta

carbon tetrachloride has been researched along with transforming growth factor beta in 221 studies

Research

Studies (221)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	24 (10.86)	18.2507
2000's	77 (34.84)	29.6817
2010's	80 (36.20)	24.3611
2020's	40 (18.10)	2.80

Authors

Authors	Studies
Heinrichs, O; Herbst, H; Milani, S; Schuppan, D	1
Biempica, L; Czaja, MJ; Shah, A; Weiner, FR; Zern, MA	1
Greenwel, P; Grimaud, JA; Peyrol, S; Rojkind, M; Rosas, M; Schwartz, M	1
Higuchi, O; Nakamura, T	1
Annoni, G; Biempica, L; Degli Esposti, S; Sun, MA; Wang, BE; Zern, MA	1
Greenwel, P; Inagaki, Y; Kobayashi, K; Ramirez, F; Rojkind, M; Truter, S; Unoura, M	1
Aikou, T; Hamanoue, M; Mitsue, S; Nakamura, T; Ogura, Y; Tanabe, G; Yoshidome, S	1
Bedossa, P; Poynard, T; Terris, B	1
de Bleser, PJ; Geerts, A; Hoogerbrugge, CM; Jannes, P; Niki, T; Rogiers, V; van Buul-Offers, SC; van den Brande, JL; van Schravendijk, CF; Wisse, E	1
Collins, S; Delaney, B; Kaminski, NE; Strom, SC	1
Armendariz-Borunda, J; Jones, CM; Kang, AH; Katai, H; Raghow, R; Seyer, JM	1
Greenwel, P; Hertzberg, EL; Rojkind, M; Rubin, J; Schwartz, M	1
Jiang, H; Wang, Q; Xia, S	1
Han, SH; Jeon, YJ; Kaminski, NE; Yang, KH	1
Armendáriz-Borunda, J; Campollo, O; LeGros, L; Panduro, A; Rincón, AR	1
Annoni, G; Arosio, B; Biasi, F; Gagliano, N; Ryan, A; Santambrogio, D; Vergani, C	1
Bursch, W; Grasl-Kraupp, B; Kammerer, B; Müllauer, L; Rossmanith, W; Ruttkay-Nedecky, B; Schulte-Hermann, R	1
Degraef, C; Demols, A; Devière, J; Geerts, A; Goldman, M; Le Moine, O; Louis, H; Quertinmont, E; Van den Berg, K; Van Laethem, JL; Wu, W	1
Ang, HK; Ho, JM; Tan, CE; Wasser, S	1
Brenner, DA; Burchardt, ER; Giordano, F; Hellerbrand, C; Stefanovic, B	1
Akiyama, M; Harada, A; Ishikura, H; Kaneko, S; Matsushima, K; Mukaida, N; Nakanishi, I; Natsume, M; Tsuji, H; Yano, T	1
Bashey, R; Frizell, E; Liu, SL; Norton, P; Rubin, R; Wu, J; Zern, MA; Zhu, J	1
Knittel, T; Krüger, M; Neubauer, K; Quondamatteo, F; Ramadori, G; Saile, B	1
De Bleser, PJ; Geerts, A; Rogiers, V; Rombouts, K; Xu, G	1
Chang, S; DePinho, RA; Millard, M; Rudolph, KL; Schreiber-Agus, N	1
Iredale, J; Williams, E	1
Date, M; Furukawa, F; Inoue, K; Matsushita, M; Matsuzaki, K; Tahashi, Y	1
Akiyama, Y; Hamanaka, Y; Hamasaki, K; Hsu, CT; Ito, M; Naito, S; Nakashima, M; Ohtsuru, A; Sekine, I	1
Armendariz-Borunda, J; Dominguez-Rosales, JA; Fontana, L; Greenwel, P; Nieto, N; Rojkind, M; Salazar, A	1
Doi, K; Nakayama, H; Shimizu, H; Uetsuka, K	1
Adachi, Y; Bradford, BU; Burchardt, ER; Hunt, KJ; Koop, DR; Rippe, RA; Rivera, CA; Schrum, LW; Thurman, RG	1
Brenner, DA; Frederick, JP; Kweon, YO; Rippe, RA; Schnabl, B; Wang, XF	1
Date, M; Furukawa, F; Himeno, Y; Inagaki, Y; Inoue, K; Matsushita, M; Matsuzaki, K; Sugano, Y; Tahashi, Y; Yoshida, K	1
Huang, Y; Li, S; Wang, C; Zhou, M	1
Anselmi, K; Gandhi, CR; Nemoto, E; Subbotin, VM	1
Farrell, GC; Leclercq, IA; Robertson, GR; Schriemer, R	1
Annoni, G; Arosio, B; Gagliano, N; Grizzi, F; Vergani, C	1
Chang, XM; Dong, L; Gong, J; Hao, ZM; Jia, A; Luo, JY; Xu, GP; Xu, JW	1
Lu, R; Shen, X; Wu, M; Xiao, J	1
Crissey, MA; Leu, JI; Taub, R	1
Mezey, E; Potter, JJ; Rennie-Tankesley, L	1
Anania, FA; Floyd, JJ; Saliba, G; Saxena, NK	1
Chen, XB; Jiang, MD; Lei, CT; Wang, PL; Wang, Z; Wu, XL; Xu, H; Zeng, WZ; Zhang, Y	1
Chen, XM; Huang, X; Li, DG; Lu, HM; Wang, YQ; Wang, ZR; Wei, HS; Xu, QF	1
Chayama, K; Kanno, K; Tazuma, S	1
Blanco, G; Borrás-Cuesta, F; Bustos, M; Castilla-Cortázar, I; Dotor, J; Ezquerro, IJ; Greenwel, P; Lasarte, JJ; Lechuga, Mdel C; Peñuelas, I; Prieto, J; Rodríguez, C; Rojkind, M	1
Arii, S; Imamura, M; Mori, A; Murata, T	1
Basilico, C; Huang, X; Jin, C; McKeehan, WL; Miller, DL; Wang, F; Yu, C	1
Akiyoshi, H; Inoue, A; Isono, M; Sato, K; Soda, M	1
Chen, ZX; Huang, YH; Li, D; Wang, XZ; Yu, JP; Zhang, LJ	1
Fukui, K; Funahashi, T; Kamada, Y; Kihara, S; Kiso, S; Maeda, N; Matsumoto, H; Matsuzawa, Y; Miyagawa, J; Nagaretani, H; Nishizawa, H; Okamoto, Y; Saji, Y; Shinomura, Y; Tamura, S; Yoshida, Y	1
Li, X; Meng, Y; Wu, PS; Yang, XS; Zhang, ZS; Zou, JL	1
Armbrust, T; Kreissig, M; Ramadori, G; Tron, K	1
Imamura, M; Itoh, H; Nie, L; Ueno, H	1
Fang, B; Liao, L; Liu, Y; Shi, M; Yang, S; Zhao, RC	1
He, ZP; Leng, XS; Xu, XB; Yang, X	1
Jun, L; Qiang, CJ; Wei, YH	1
Chen, JQ; Li, J; Xu, SY; Yao, HW	1
Brenner, DA; Fagin, JA; Fuller, CR; Liu, S; Lund, PK; Martínez-Chantar, ML; Pardo, A; Prieto, J; Pucilowska, JB; Rodríguez-Ortigosa, CM; Sanz, S; Simmons, JG	1
Gong, ZJ; Huang, YQ; Ruan, P; Song, SL	1
Do, SH; Jeong, DH; Jeong, KS; Jeong, WI; Kim, KJ; Lee, GP; Park, HY; Yang, HJ; Yuan, DW	1
Moriwaki, H; Saito, K; Seishima, M; Sudo, K; Yamada, Y	1
Bouscarel, B; Doy, M; Ikegami, T; Karube, M; Matsuzaki, Y; Miyazaki, T; Tanaka, N	1
Cederbaum, AI; Nieto, N	1
Bou-Gharios, G; Higashi, K; Higashiyama, R; Hong, YY; Ikeda, K; Inagaki, Y; Itoh, J; Kawada, N; Kiyama, H; Kushida, M; Namikawa, K; Okazaki, I; Watanabe, T	1
Arezzini, B; Comporti, M; Gardi, C; Monaco, B; Sgherri, C; Signorini, C	1
Ding, J; Hu, W; Li, D; Luo, H; Luo, Y; Wang, C; Yu, H; Yu, J	1
He, L; Liu, SQ; Luo, HS; Yu, HG; Yu, JP	1
Lin, WC; Lin, WL	1
Bollito, E; Tessitore, L	1
Farnworth, SL; Haslett, C; Henderson, NC; Iredale, JP; Mackinnon, AC; Poirier, F; Russo, FP; Sethi, T; Simpson, KJ	1
Akahane, T; Asada, K; Fukui, H; Ikenaka, Y; Kitade, M; Kuriyama, S; Namisaki, T; Noguchi, R; Tsujimoto, T; Uemura, M; Yamazaki, M; Yanase, K; Yoshii, J; Yoshiji, H	1
Fan, ST; Glockzin, G; Lau, CK; Ma, J; Obed, A; Schlitt, HJ; Tsui, TY	1
Inoue, K; Kodai, S; Minamiyama, Y; Mizuguchi, S; Okada, S; Suehiro, S; Takemura, S; Tsukioka, T	1
Jiang, S; Jin, Y; Li, D; Li, G; Lu, H; Shi, Y; Xie, Q; Zhang, M; Zhou, H	1
Chen, ZX; Huang, YH; Shi, MN; Wang, XZ; Zhang, LJ; Zheng, WD	1
Fang, HL; Kuo, SC; Lin, WC; Lin, WL; Wang, BC	1
Chayama, K; Horiuchi, M; Hyogo, H; Iwai, M; Kanno, K; Nabeshima, Y; Tazuma, S	1
Fu, H; He, SX; Liu, EQ; Luo, JY; Wang, YL; Wang, YP; Xu, JL; Zhao, G	1
Chávez, E; Moreno, MG; Muriel, P; Reyes-Gordillo, K; Segovia, J; Shibayama, M; Tsutsumi, V; Vergara, P	1
Fujimoto, J; Hirano, T; Iimuro, Y; Kaneda, Y; Seki, E; Son, G	1
Ciuclan, L; Dooley, S; Ehnert, S; Godoy, P; Hamzavi, J; Heuchel, R; Mertens, PR; Weng, H	1
Jiang, MD; Qin, JP; Wu, XL; Xu, H; Zeng, WZ	1
Lindhorst, A; Neubauer, K; Ramadori, G; Saile, B; Tron, K	1
Castilla, A; Castilla-Cortázar, I; Clavijo, E; García Fernández, M; Juanarena, N; Monreal, I; Puche, JE; Rodríguez-Ortigosa, C; Tutau, F	1
Breitkopf, K; Ciuclan, L; Dooley, S; Ehnert, S; Gebhardt, R; Geier, A; Godoy, P; Hamzavi, J; Ilkavets, I; Kanzler, S; Mertens, PR; Ueberham, E; Weng, H	1
Aoyagi, Y; Fukunaga, K; Hashimoto, I; Ikeda, O; Matsuo, R; Murata, S; Nakano, Y; Ohkohchi, N; Watanabe, M; Yasue, H	1
Galicia-Moreno, M; Moreno, MG; Muriel, P; Reyes-Gordillo, K; Rodríguez-Rivera, A; Segovia, J; Shibayama, M; Tsutsumi, V; Vergara, P	2
Armendáriz-Borunda, J; Castrejón-Gómez, E; López-Reyes, A; Ruiz-Corro, L; Salazar-Montes, A	1
Moreno, MG; Muriel, P; Reyes-Gordillo, K; Segovia, J; Shibayama, M; Tsutsumi, V; Vergara, P	1
Behrns, KE; Kim, JS; Mohuczy, D; Nitta, T	1
Khimji, AK; Rockey, DC; Shao, R	1
Chen, YX; Hu, PF; Lin, Y; Xie, WF; Yin, C; Yue, HY; Zhang, X; Zhong, W; Zhu, YW	1
Fernández-Martínez, E; Galicia-Moreno, M; Moreno, MG; Muriel, P; Pérez-Alvarez, VM; Reyes-Gordillo, K; Rodríguez-Rivera, A; Segovia, J; Shibayama, M; Tsutsumi, V; Vergara, P	1
Fernández-Checa, JC; Marí, M; Moles, A; Tarrats, N	1
Cubero, FJ; Nieto, N; Urtasun, R; Vera, M	1
Hennighausen, L; Hosui, A; Kimura, A; Na, R; Yamaji, D; Zhu, BM	1
Flavell, RA; Gomes, DA; Hashmi, A; Jhandier, MN; Mahmood, S; Mehal, WZ; Nagata, J; Shi, Y; Sohail, MA; Sutterwala, FS; Watanabe, A	1
Gao, XL; Liu, P; Qian, W; Xu, KS; Yu, J	1
Dabeva, MD; Grozdanov, PN; Neufeld, DS; Yovchev, MI; Zhang, J	1
Chan, HH; Chao, D; Chen, CL; Cheng, KH; Cheng, YF; Chung, YH; Goto, S; Hu, TH; Jawan, B; Kao, YH; Kuo, SM; Lin, YC; Sun, CK; Tai, MH; Wu, DC	1
Liu, A; Lourensz, D; Manuelpillai, U; Samuel, CS; Sievert, W; Tchongue, J; Vaghjiani, V; Williams, ED	1
Castro-Sánchez, L; Chávez, E; Moreno, MG; Muriel, P; Salazar, EP; Segovia, J; Shibayama, M; Tsutsumi, V; Vergara, P	1
Hwang, SG; Jung, J; Kim, GI; Kim, GJ; Kim, JH; Kwon, SW; Lee, HJ; Lee, MJ; Moon, JS; Na, KH	1
Higashi, K; Inagaki, Y; Kaneko, H; Kimura, T; Mikami, T; Miyata, K; Moro, T; Shiraki, H; Tomigahara, Y	1
Friedman, SL; Kwong, SQ; Lam, RWC; Li, FR; Liu, Y; Lui, ELH; Wang, Z; Ye, T; Zhang, GC; Zhang, H	1
Jia, J; Wang, H; Wang, T; You, H; Zhang, Y	1
Baffet, G; Bonnier, D; Bourd-Boittin, K; Ezan, F; Leyme, A; Mari, B; Samson, M; Theret, N; Tuffery, P	1
Chen, LJ; Chen, ZZ; Cheng, P; Deng, CY; Luo, YF; Wang, XH; Wang, ZL; Xie, CF; Zheng, H	1
Brouillet, A; Chobert, MN; Couchie, D; Fourcot, A; Laperche, Y; Mavier, P; Zafrani, ES	1
Ebinuma, H; Hibi, T; Hiroi, S; Hokari, R; Irie, R; Kanai, T; Kurihara, C; Miura, S; Okada, Y; Oshikawa, T; Saito, H; Shimamura, K; Sugiyama, K; Suzuki, T; Teratani, T; Tominaga, S; Tomita, K; Yokoyama, H	1
Knight, V; Lourensz, D; Sievert, W; Tchongue, J; Tipping, P	1
Azevedo, CM; de Freitas Souza, BS; de Freitas, LA; de Oliveira, SA; Guimarães, ET; Kaneto, CM; Neto, HA; Ribeiro-Dos-Santos, R; Sá Barreto, EP; Soares, MB	1
Bugyik, E; Dezso, K; Nagy, P; Paku, S; Szurián, K; Turányi, E	1
He, RH; Huang, XR; Lan, HY; Meng, XM; Tan, JJ; Tang, LX; Yang, G; Zhou, L	1
Castro-Sánchez, L; Chávez, E; Moreno, MG; Muriel, P; Shibayama, M; Tsutsumi, V	1
Arteta, B; Beraza, N; Caballeria, J; Embade, N; Fernández-Ramos, D; García-Rodríguez, JL; Gutiérrez-De Juan, V; Iruarrizaga-Lejarreta, M; Lu, SC; Martínez-Chantar, ML; Martínez-López, N; Mato, JM; Varela-Rey, M; Woodhoo, A	1
Cai, Y; Fu, D; Shen, XZ; Zhou, CH	1
Chen, Z; Fu, S; Huang, J; Huang, Q; Huang, R; Jiao, Y; Lin, X; Wei, L; Zhang, S; Zheng, L	1
Hennighausen, L; Kang, K; Riedlinger, G; Yu, JH; Zhu, BM	1
Dong, HY; Fan, L; Li, G; Liu, JC; Niu, YC; Zhang, C; Zhang, YB; Zhao, XM; Zou, Y	1
Dapito, DH; Friedman, RA; Gwak, GY; Hsu, CC; Mederacke, I; Mu, X; Pradere, JP; Schwabe, RF; Troeger, JS	1
Kweon, YO; Lee, JY; Lee, MS; Park, SY; Tak, WY	1
Crosas-Molist, E; Eferl, R; Fabregat, I; Fernández-Rodriguez, CM; Huber, H; Mainez, J; Mikulits, W; Pinedo, F; Roncero, C; Sancho, P	1
Chen, X; Li, J; Liu, XQ; Tao, L; Wang, H; Wang, JQ; Xu, DX; Xu, YB; Zhang, C; Zhang, ZH	1
Friedman, SL; Ji, L; Kwong, S; Lam, W; Li, F; Liu, Y; Lui, EL; Ren, Q; Tang, S; Wang, J; Wang, X; Wang, Z; Xu, Z; Ye, T; Zhang, H; Zhou, S	1
Asahina, K; Li, Y; Wang, J	1
Boyle, PM; Duncan, MB; Kalluri, R; Keskin, D; Olsen, BR; Sugimoto, H; Tanjore, H; Yang, C; Zeisberg, M	1
Ishikawa, F; Kado, S; Kano, M; Kobayashi, T; Kubota, N; Masuoka, N; Miyazaki, K; Nagata, Y	1
Dong, W; Lv, B; Wei, F; Yang, L	1
Bennett, RG; Heimann, DG; Simpson, RL; Singh, S; Tuma, DJ	1
Dooley, S; Hall, RA; Lammert, F; Liebe, R; Williams, RW	1
Fukunaga, K; Murata, S; Ohkohchi, N; Takahashi, K	1
Aldaba-Muruato, LR; Moreno, MG; Muriel, P; Shibayama, M; Tsutsumi, V	1
Chen, J; Dong, L; Gao, Z; Hu, W; Huang, Z; Zang, Y; Zha, Y; Zhang, J; Zhang, Z	1
Deng, WS; Gu, L; Sun, XF; Xu, Q	1
Gao, X; Han, D; Jin, J; Li, F; Luo, S; Lv, G; Ma, N; Qiao, Y; Wang, L; Wu, G; Xiang, Y; Xu, C; Xu, Y; Yan, B; Zhang, Y; Zhao, R	1
Chung, LC; Day, CH; Huang, CY; Ju, DT; Ting, WJ; Tsai, CH; Tsai, FJ; Tsai, Y; Yang, CH; Yeh, YL	1
Bou-Gharios, G; Jawaid, S; Sakai, K; Sakai, T; Sasaki, T	1
Muriel, P; Pérez-Vargas, JE; Segovia, J; Shibayama, M; Tsutsumi, V; Zarco, N	1
Jeong, B; Jo, I; Jung, SC; Kim, HS; Kim, YH; Lee, H; Lee, HJ; Park, JW; Park, M; Park, YS; Ryu, KH; Woo, SY; Yu, Y	1
Cameron, AM; Chivukula, RR; Clark, KR; Creamer, TJ; Hwang, HW; Karhadkar, S; Knabel, MK; Mendell, JT; Montgomery, RA; Ramachandran, K; Sheikh, F; Torbenson, M; Warren, DS	1
Choi, MK; Han, JM; Kim, HG; Lee, JS; Park, HJ; Son, CG; Wang, JH	1
Aldridge, V; Buckley, CD; Croft, AP; Fear, J; Garg, A; Haldar, D; Hedegaard, D; Henderson, NC; Naylor, AJ; Newsome, PN; Reynolds, GM; Weston, CJ; Wilhelm, A	1
Alder, J; Benz, F; Gautheron, J; Hellerbrand, C; Luedde, T; Pottier, N; Roderburg, C; Roy, S; Schneider, A; Tacke, F; Trautwein, C; Vargas Cardenas, D; Vucur, M	1
Chang, SH; Hsu, HH; Huang, CY; Lin, YM; Padma, VV; Shen, CY; Ting, WJ; Tsai, FJ; Tsai, Y; Yang, CH	1
Fu, W; Kim-Kaneyama, JR; Lei, XF; Li, B; Miyazaki, A; Miyazaki, T; Omoto, T	1
Akhtar, R; Iwasaki, A; Keene, DR; Miyazono, T; Morishita, S; Moriya, K; Sakai, K; Sakai, T; Sasaki, T; Watanabe, M; Yasumura, S	1
Campos-Esparza, Mdel R; Cervantes-García, D; Elías-Flores, TG; Gerardo-Rodríguez, M; Llamas-Ramírez, RW; Muñoz-Fernández, L; Muñoz-Ortega, MH; Romero-Delgadillo, NI; Tavares-Rodríguez, Ede J; Ventura-Juárez, J	1
Hashimoto, S; Ido, A; Kanmura, S; Kumagai, K; Mawatari, S; Morinaga, Y; Moriuchi, A; Sasaki, F; Tabu, K; Takami, Y; Tamai, T; Tanoue, S; Tsubouchi, H; Uto, H	1
Cai, FJ; Ding, JG; Du, QW; Fu, RQ; Hong, L; Sun, QF; Wu, YH; Xu, S; Xu, TY; Zhang, D; Zhang, H; Zhou, K; Zhou, QQ	1
He, Q; Lei, F; Lei, X; Li, R; Tan, H	1
Geng, Y; Li, W; Lu, ZM; Shi, JS; Sun, Q; Xu, HY; Xu, ZH	1
Li, W; Liu, F; Liu, J; Xiong, P; Xu, D; Zhang, J; Zhu, J	1
Bansal, R; Öztürk Akcora, B; Prakash, J; Storm, G	1
Bugyik, E; Dezső, K; Mózes, M; Nagy, P; Paku, S; Rókusz, A; Szücs, A; Veres, D	1
Banik, A; Garg, M; Kaur, S; Kumar, V; Mukhopadhyay, A; Rastogi, A; Sarin, SK; Trehanpati, N	1
Cao, Y; Chen, Q; Li, Y; Sun, S; Zhang, G; Zhang, H; Zhang, J	1
Adams, DH; Birdsey, GM; Chauhan, A; Dufton, NP; Kalna, V; Lalor, P; Mason, JC; Osuna-Almagro, L; Peghaire, CR; Raimondi, C; Randi, AM; Webb, G; Yang, Y	1
Chen, M; Ling, W; Liu, J; Yang, W	1
Ahmad Bhat, S; Ahmad, B; Ahmad, SB; Ahmad, SP; Farooq, A; Fatima, B; Hussain, I; Mir, MUR; Muzamil, S; Rashid, SM; Razzaq, R; Rehman, MU	1
Chen, L; Li, W; Liu, J; Wang, B; Yu, J; Zhang, J; Zhang, Y; Zhang, Z; Zheng, W; Zhu, J; Zhuo, Q	1
Abdelghany, RH; El-Ahwany, E; Helal, NS; Mahmoud, AAA; Saber, S	1
Bordukalo-Niksic, T; Brkljacic, J; Bubic-Spoljar, J; Dumic-Cule, I; Erjavec, I; Grgurevic, I; Grgurevic, L; Kufner, V; Matijasic, M; Novak, R; Paljetak, HC; Pauk, M; Plecko, M; Rogic, D; Verbanac, D; Vukicevic, S	1
Du, M; Li, W; Liu, J; Luo, Z; Pan, Y; Wang, B; Xiong, P; Xu, D; Yu, J; Zhang, J; Zhang, Z; Zheng, W; Zhu, J	1
Nie, Y; Pan, R; Ruan, W; Shen, X; Wu, Y	1
Gui, S; Liu, G; Liu, J; Lu, B; Pian, L	1
Arab, JP; Cao, S; De Assuncao, TM; Greuter, T; Huebert, RC; Jalan-Sakrikar, N; Lomberk, G; Martin-Mateos, R; Mathison, AJ; Mathurin, P; Shah, VH; Urrutia, R; Verma, VK; Yaqoob, U	1
Hashemnia, M; Karimi, J; Khodadadi, I; Mohseni, R; Tavilani, H	1
Jiang, H; Ma, J; Qiu, Y; Wang, M; Zhang, M; Zhao, X	1
Cho, IJ; Cho, SS; Jegal, KH; Ka, SO; Ki, SH; Kim, JK; Kim, KM; Ku, SK; Lee, HJ; Na, CS; Park, BH; Park, SG; Shin, SM; Yang, JH	1
Huang, Y; Jiang, R; Jiang, X; Li, X; Ling, W; Pang, N; Pei, L; Qiu, Y; Wan, T; Wang, S; Yang, H; Yang, L; Ye, M; Zhang, Z; Zhou, Y	1
Akcora, BÖ; Bansal, R; Dathathri, E; Gabriël, AV; Ortiz-Perez, A; Prakash, J; Storm, G	1
Agarwal, SK; Pedroza, M; Smith, J; To, S	1
Beckett, JD; Bedja, D; Butcher, JT; Chen, Y; Creamer, TJ; Dietz, HC; Gould, RA; Hata, S; Kim, DH; MacFarlane, EG; Mitzner, W; Nagpal, V; Rouf, R; Seman-Senderos, MA; Warren, DS	1
Badr, G; Hassan, KA; Mahmoud, MH; Sayed, EA; Selamoglu, Z; Waly, H	1
Chen, J; Chen, W; Cong, M; Dooley, S; Fan, W; Fu, Y; Hammad, S; Hausser, I; He, Y; Hou, J; Hui, L; Jia, J; Li, D; Li, L; Li, N; Lian, Q; Ling, Z; Liu, C; Liu, T; Liu, Z; Longerich, T; Ma, L; Sun, B; Wang, P; Wang, Y; Xu, H; Yan, C; Yi, C; You, H; Zhang, Y; Zhao, X	1
Kong, D; Liu, J; Liu, X; Lu, Z; Qiu, J; Wang, Y; Xie, Y; Zhang, R; Zhou, C	1
Li, C; Rong, X; Wang, Y; Yang, Y; Zhang, G; Zhang, H	1
Artmann, R; Bösch, F; de Toni, EN; Denk, G; Gerbes, AL; Hohenester, S; Kanitz, V; Mayerle, J; Mayr, D; Regel, I; Reiter, FP; Steib, CJ; Trauner, M; Wimmer, R; Ye, L; Ziesch, A	1
Chen, T; Li, J; Xiao, P; Xie, X; Yan, X; Zhang, L; Zhou, D; Zhu, J	1
Chen, X; Cheng, J; Feng, S; Han, K; Han, M; Liang, P; Liu, S; Lu, H; Wang, Y; Yuan, X; Zhao, J; Zhou, L	1
Chale-Dzul, J; Moo-Puc, R; Olivera-Castillo, L; Pérez-Cabeza de Vaca, R; Quintal-Novelo, C	1
Fathy, M; Okabe, M; Saad Eldien, HM; Yoshida, T	1
Hausser, A; Ishikawa, E; Jin, ZG; Liu, H; Pei, X; Yamasaki, S; Yin, M; Zhang, S	1
Chen, J; Chen, K; Dai, W; Fan, X; Feng, J; Guo, C; Ji, J; Li, J; Mao, Y; Wang, F; Wu, J; Wu, L; Xu, S; Yu, Q; Zhang, J; Zhou, Y	1
Abdelgwad, M; Alhelf, M; Altaib, ZM; Ewaiss, M; Khalifa, WA; Sabry, D	1
Li, HT; Li, XX; Shi, YS; Zhang, Y	1
Bai, J; Bi, Z; Li, H; Li, X; Ma, B; Ma, X; Ning, W; Shao, S; Wei, Y; Xie, C; Yang, C; Zhang, L; Zhang, R; Zhang, S; Zhou, H	1
Chen, X; Kong, L; Luo, J; Xiang, D; Zhang, H; Zhu, X; Zou, J	1
He, J; Huang, C; Huang, H; Huang, Y; Li, R; Li, Y; Liu, Q; Mo, L; Tang, Q; Wu, T; Zhang, G; Zhang, J; Zhang, Z; Zhao, Y; Zhou, J	1
Chen, T; Du, X; Han, T; Hong, W; Shao, S; Shi, Z; Zhang, K; Zhang, Y; Zhao, Y; Zheng, L	1
Cho, SS; Jeong, EH; Ki, SH; Kim, JH; Kim, KM; Kim, SJ; Lee, JH; Park, EY; Seo, KH; Yang, JH	1
Chen, G; Guo, J; Liang, X; Ma, R; Wang, X; Yu, W; Zhu, L; Zhu, Y	1
Ijaz, B; Koloko, BL; Malik, A; Rehman, S; Shahid, AA; Tariq, S	1
Cho, ILJ; Ki, SH; Ku, SK; Lee, JH; Na, CS; Yang, JH	1
Cao, W; Feng, YD; Kang, R; Li, C; Li, XQ; Li, ZZ; Sun, Y; Tian, W; Zhang, HN	1
Chien, CY; Hsu, FY; Lee, YC; Liao, YJ; Wang, YH; Wu, CY	1
Lv, XW; Shuai, C; Wang, S; Xia, GQ; Yuan, F	1
Abbas, A; Ahmad, S; Ahmed, A; Ali, U; Chen, G; Hussain, A; Khan, H; Liu, D; Qiu, Z; Raza, F; Shafiq, M; Ullah, A; Usman, M; Zheng, M; Zhou, Z	1
Liu, LL; Wang, JH; Wang, L; Zhao, TJ; Zheng, Y	1
Ba, Q; Gu, P; Jiang, Z; Li, J; Li, W; Li, X; Liu, C; Sun, M; Wang, H; Wang, W; Yang, Y; You, R	1
Jia, QA; Li, HY; Sun, BR; Wang, GP; Zhang, C	1
Chen, Y; Li, Y; Lin, L; Que, R; Zhang, N; Zhou, M	1
Chen, GF; Chen, JM; Fu, YD; Gao, SQ; Hu, YH; Ji, Q; Liu, P; Liu, W; Mu, YP; Xiao, Z	1
Chen, R; Chen, X; Cong, W; Dong, Y; Fan, J; Hu, Z; Huang, P; Jin, L; Jin, Z; Lee, J; Li, S; Li, X; Mei, L; Sui, Y; Tong, G; Wang, X; Zhou, B; Zhu, K	1
Bai, L; Chen, YL; Duan, SZ; Li, HX; Liu, Y; Song, ZC; Wang, YL; Zhu, SW	1
Chalasani, N; Culver, A; Dai, G; Garcia, V; Hamang, M; Jiang, H; Kusumanchi, P; Lee, J; Liangpunsakul, S; Wang, Y; White, E; Yaden, BC; Yanum, J	1
Fang, Y; Jiang, C; Qiu, J; Wang, P; Wang, Z; Zhou, Y	1
Alisi, A; Bianchi, M; Braghini, MR; Comparcola, D; Condorelli, AG; Conti, LA; Crudele, A; De Stefanis, C; Gurrado, F; Lioci, G; Mosca, A; Nobili, R; Panera, N; Sartorelli, MR; Scoppola, V; Smeriglio, A; Svegliati-Baroni, G; Trombetta, D	1
Feng, J; Fu, Q; Guo, J; Ling, B; Ning, K; Wang, J; Wu, B; Xiu, G; Xu, J	1
Gao, C; Hong, J; Kang, Z; Li, J; Qu, H; Wu, J; Xiao, Y; You, Y	1
Cheng, GL; Li, YR; Tan, YJ; Wang, EL; Yao, JC; Zhang, GM; Zhao, Y; Zhao, YF	1
Guo, Q; Huang, ZL; Ji, LL; Lu, B; Zhang, Y	1
Allur-Subramaniyan, S; Doods, H; Feng, H; Lee, D; Pekcec, A; Rampa, DR; Shim, K; Wu, D	1
Ao, J; Chiba, T; Fujita, N; Fujiwara, K; Honda, T; Inoue, M; Ishino, T; Iwanaga, T; Kan, M; Kanda, T; Kaneko, T; Kanogawa, N; Kanzaki, H; Kato, J; Kato, N; Kiyono, S; Kobayashi, K; Kogure, T; Kondo, T; Koroki, K; Kusakabe, Y; Ma, Y; Maruyama, H; Mimura, N; Murayama, T; Muroyama, R; Nakagawa, M; Nakagawa, R; Nakamoto, S; Nakamura, H; Nakamura, M; Ogasawara, S; Ogawa, K; Qiang, N; Sakuma, T; Yumita, S; Zhang, J	1
Chen, S; Cheng, J; Dong, L; Fu, R; Han, P; Li, R; Li, S; Liu, Z; Pei, H; Shen, X; Song, G; Song, Y; Wang, H; Wei, J; Wu, J; Yao, Q; Zhang, G; Zhang, S; Zhao, Y; Zhu, C; Zhu, J	1
Guo, F; Song, Y; Zhang, N	1
Bao, B; Chen, L; Chen, X; Li, C; Sun, Y; Zhou, Y	1
Cai, X; Dong, H; Guo, Y; Lu, J; Lu, L; Luo, X; Luo, Y; Qu, Y; Shen, B; Shen, Z; Sun, Z; Wang, J; Xu, X; Ye, Y; Zhang, Q; Zhou, C	1

Trials

1 trial(s) available for carbon tetrachloride and transforming growth factor beta

Article	Year
The autoregulatory feedback loop of microRNA-21/programmed cell death protein 4/activation protein-1 (MiR-21/PDCD4/AP-1) as a driving force for hepatic fibrosis development. The Journal of biological chemistry, 2013, Dec-27, Volume: 288, Issue:52 Topics: Adult; Aged; Animals; Apoptosis Regulatory Proteins; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Female; Hepatic Stellate Cells; Humans; Liver Cirrhosis, Experimental; Male; Mice; Mice, Inbred ICR; MicroRNAs; Middle Aged; RNA-Binding Proteins; Signal Transduction; Thioacetamide; Transcription Factor AP-1; Transforming Growth Factor beta	2013

Article

Year

The autoregulatory feedback loop of microRNA-21/programmed cell death protein 4/activation protein-1 (MiR-21/PDCD4/AP-1) as a driving force for hepatic fibrosis development.

The Journal of biological chemistry, 2013, Dec-27, Volume: 288, Issue:52

Topics: Adult; Aged; Animals; Apoptosis Regulatory Proteins; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Female; Hepatic Stellate Cells; Humans; Liver Cirrhosis, Experimental; Male; Mice; Mice, Inbred ICR; MicroRNAs; Middle Aged; RNA-Binding Proteins; Signal Transduction; Thioacetamide; Transcription Factor AP-1; Transforming Growth Factor beta

2013

Other Studies

220 other study(ies) available for carbon tetrachloride and transforming growth factor beta

Article	Year
[Pathomorphology of acute and chronic stages of CCl4-induced liver fibrosis: immunohistochemical and in situ hybridization studies]. Zeitschrift fur Gastroenterologie, 1992, Volume: 30 Suppl 1 Topics: Animals; Carbon Tetrachloride; Extracellular Matrix Proteins; Humans; Immunoenzyme Techniques; In Situ Hybridization; Liver; Liver Cirrhosis; Liver Cirrhosis, Experimental; Liver Regeneration; Procollagen; Proto-Oncogene Proteins; Rats; RNA Probes; Transcription, Genetic; Transforming Growth Factor beta	1992
The effects of hepatic fibrosis on Ito cell gene expression. Matrix (Stuttgart, Germany), 1992, Volume: 12, Issue:1 Topics: Animals; Carbon Tetrachloride; Endothelium; Extracellular Matrix Proteins; Gene Expression Regulation; Kupffer Cells; Liver Cirrhosis, Experimental; Male; Neoplasm Proteins; Phenotype; Rats; Rats, Inbred Strains; RNA, Messenger; RNA, Neoplasm; Transforming Growth Factor beta	1992
Characterization of fat-storing cell lines derived from normal and CCl4-cirrhotic livers. Differences in the production of interleukin-6. Laboratory investigation; a journal of technical methods and pathology, 1991, Volume: 65, Issue:6 Topics: Adipose Tissue; Animals; Carbon Tetrachloride; Cell Line; Collagen; Fibronectins; Interleukin-6; Liver; Liver Cirrhosis, Experimental; Male; Microscopy, Electron; Platelet-Derived Growth Factor; Rats; Rats, Inbred Strains; Transforming Growth Factor beta	1991
Identification and change in the receptor for hepatocyte growth factor in rat liver after partial hepatectomy or induced hepatitis. Biochemical and biophysical research communications, 1991, Apr-30, Volume: 176, Issue:2 Topics: Animals; Carbon Tetrachloride; Cell Membrane; Cells, Cultured; Chemical and Drug Induced Liver Injury; Cross-Linking Reagents; DNA; Down-Regulation; Epidermal Growth Factor; Growth Substances; Hepatectomy; Hepatocyte Growth Factor; Humans; Liver; Liver Regeneration; Male; Molecular Weight; Rats; Rats, Inbred Strains; Recombinant Proteins; Transforming Growth Factor alpha; Transforming Growth Factor beta	1991
Two rat models of hepatic fibrosis. A morphologic and molecular comparison. Laboratory investigation; a journal of technical methods and pathology, 1990, Volume: 63, Issue:4 Topics: Animals; Antigen-Antibody Complex; Carbon Tetrachloride; Collagen; Disease Models, Animal; Gene Expression; Humans; Infant, Newborn; Liver Cirrhosis, Experimental; Male; Rats; Rats, Inbred Strains; RNA, Messenger; Transforming Growth Factor beta	1990
Regulation of the alpha 2(I) collagen gene transcription in fat-storing cells derived from a cirrhotic liver. Hepatology (Baltimore, Md.), 1995, Volume: 22, Issue:2 Topics: Adipocytes; Animals; Binding Sites; Blotting, Northern; Carbon Tetrachloride; Collagen; Gene Expression Regulation; Humans; Liver Cirrhosis, Experimental; Nuclear Proteins; Phenotype; Rats; Regulatory Sequences, Nucleic Acid; RNA, Messenger; Transcription, Genetic; Transfection; Transforming Growth Factor beta	1995
Expression of HGF and TGF-beta 1 mRNA after partial hepatectomy in rats with liver cirrhosis. Surgery today, 1995, Volume: 25, Issue:3 Topics: Animals; Carbon Tetrachloride; Hepatectomy; Hepatocyte Growth Factor; Liver Cirrhosis, Experimental; Liver Regeneration; Male; Rats; Rats, Wistar; RNA, Messenger; Transaminases; Transforming Growth Factor beta	1995
No effect of neutralizing antibody to TGF-beta 1 in acute CC14-induced liver fibrogenesis. Journal of hepatology, 1994, Volume: 21, Issue:6 Topics: Acute Disease; Animals; Antibodies; Carbon Tetrachloride; Liver; Liver Cirrhosis, Experimental; Male; Procollagen; Rats; Rats, Wistar; RNA, Messenger; Transforming Growth Factor beta	1994
Insulinlike growth factor-II/mannose 6-phosphate receptor is expressed on CCl4-exposed rat fat-storing cells and facilitates activation of latent transforming growth factor-beta in cocultures with sinusoidal endothelial cells. Hepatology (Baltimore, Md.), 1995, Volume: 21, Issue:5 Topics: Animals; Blotting, Northern; Carbon Tetrachloride; Cells, Cultured; Cross-Linking Reagents; Cytological Techniques; Endothelium; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Lipid Metabolism; Liver; Male; Rats; Rats, Wistar; Receptor, IGF Type 2; Transforming Growth Factor beta	1995
Carbon tetrachloride suppresses T-cell-dependent immune responses by induction of transforming growth factor-beta 1. Toxicology and applied pharmacology, 1994, Volume: 126, Issue:1 Topics: Animals; Antibody-Producing Cells; Carbon Tetrachloride; Immunosuppressive Agents; Interleukin-2; Mice; Mice, Inbred Strains; Receptors, Interleukin-2; Spleen; T-Lymphocytes; Transforming Growth Factor beta	1994
Transforming growth factor beta gene expression is transiently enhanced at a critical stage during liver regeneration after CCl4 treatment. Laboratory investigation; a journal of technical methods and pathology, 1993, Volume: 69, Issue:3 Topics: Animals; Antibodies; Carbon Tetrachloride; Cell Division; Cells, Cultured; DNA Replication; Gene Expression; Immunohistochemistry; In Situ Hybridization; Liver; Liver Regeneration; Male; Rats; Rats, Wistar; Reference Values; RNA, Messenger; Thymidine; Transcription, Genetic; Transforming Growth Factor beta	1993
Liver fat-storing cell clones obtained from a CCl4-cirrhotic rat are heterogeneous with regard to proliferation, expression of extracellular matrix components, interleukin-6, and connexin 43. Laboratory investigation; a journal of technical methods and pathology, 1993, Volume: 69, Issue:2 Topics: Animals; Carbon Tetrachloride; Cell Division; Clone Cells; Connexins; Extracellular Matrix Proteins; Interleukin-6; Lipid Metabolism; Liver; Liver Cirrhosis, Experimental; Membrane Proteins; Rats; RNA, Messenger; Transforming Growth Factor beta	1993
[The mechanism for splenic promoting effects on liver cirrhosis]. Zhonghua yi xue za zhi, 1995, Volume: 75, Issue:10 Topics: Animals; Carbon Tetrachloride; Cells, Cultured; Collagen; Fibronectins; Laminin; Liver Cirrhosis, Experimental; Rats; Rats, Sprague-Dawley; Spleen; Splenectomy; Transforming Growth Factor beta	1995
Induction of liver-associated transforming growth factor beta 1 (TGF-beta 1) mRNA expression by carbon tetrachloride leads to the inhibition of T helper 2 cell-associated lymphokines. Toxicology and applied pharmacology, 1997, Volume: 144, Issue:1 Topics: Acetaminophen; Animals; Carbon Tetrachloride; Female; Gene Expression Regulation; Immunoglobulin M; Liver; Lymphokines; Mice; Mice, Inbred Strains; NF-kappa B; Pregnancy; Protein Binding; RNA, Messenger; Spleen; Th2 Cells; Transforming Growth Factor beta	1997
Antisense S-oligodeoxynucleotides down-regulate TGFbeta-production by Kupffer cells from CCl4-injured rat livers. Biochimica et biophysica acta, 1997, Sep-12, Volume: 1353, Issue:3 Topics: Animals; Carbon Tetrachloride; Cells, Cultured; Gene Expression Regulation; Kupffer Cells; Liver; Macrophages; Oligonucleotides, Antisense; Rats; RNA, Messenger; Thionucleotides; Transforming Growth Factor beta	1997
Glutathione pretreatment lessens the acute liver injury induced by carbon tetrachloride. Pharmacology & toxicology, 1997, Volume: 81, Issue:4 Topics: Animals; Biomarkers; Blotting, Northern; Carbon Tetrachloride; Erythrocytes; Glutathione; Liver; Male; Necrosis; Procollagen; Rats; Rats, Sprague-Dawley; RNA, Messenger; Serum Albumin; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha	1997
Levels of transforming growth factor beta and transforming growth factor beta receptors in rat liver during growth, regression by apoptosis and neoplasia. Hepatology (Baltimore, Md.), 1998, Volume: 28, Issue:3 Topics: Animals; Apoptosis; Carbon Tetrachloride; Female; Hyperplasia; Liver; Liver Neoplasms, Experimental; Lymphotoxin beta Receptor; Male; Rats; Rats, Wistar; Receptors, Tumor Necrosis Factor; RNA, Messenger; Transforming Growth Factor beta	1998
Interleukin-10 controls neutrophilic infiltration, hepatocyte proliferation, and liver fibrosis induced by carbon tetrachloride in mice. Hepatology (Baltimore, Md.), 1998, Volume: 28, Issue:6 Topics: Animals; Carbon Tetrachloride; Cell Division; Cell Movement; Chemical and Drug Induced Liver Injury; Injections; Interleukin-10; Interleukin-6; Liver; Liver Cirrhosis, Experimental; Mice; Mice, Inbred C57BL; Mice, Knockout; Necrosis; Neutrophils; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha	1998
Salvia miltiorrhiza reduces experimentally-induced hepatic fibrosis in rats. Journal of hepatology, 1998, Volume: 29, Issue:5 Topics: Animals; Carbon Tetrachloride; Drugs, Chinese Herbal; Extracellular Matrix Proteins; Free Radical Scavengers; Liver Cirrhosis, Experimental; Male; Plant Extracts; Rats; Rats, Wistar; Salvia miltiorrhiza; Transforming Growth Factor beta	1998
The role of TGFbeta1 in initiating hepatic stellate cell activation in vivo. Journal of hepatology, 1999, Volume: 30, Issue:1 Topics: Actins; Animals; Carbon Tetrachloride; Collagen; Growth Inhibitors; Humans; Liver; Mice; Mice, Knockout; Muscle, Smooth; Recombinant Proteins; Reference Values; RNA, Messenger; Transduction, Genetic; Transforming Growth Factor beta	1999
Attenuated liver fibrosis and depressed serum albumin levels in carbon tetrachloride-treated IL-6-deficient mice. Journal of leukocyte biology, 1999, Volume: 66, Issue:4 Topics: Animals; Carbon Tetrachloride; Female; Gene Expression; Hepatocyte Growth Factor; Interleukin-6; Liver Cirrhosis, Experimental; Mice; Mice, Inbred BALB C; Mice, Knockout; Serum Albumin; Transforming Growth Factor beta	1999
Rapamycin inhibits hepatic stellate cell proliferation in vitro and limits fibrogenesis in an in vivo model of liver fibrosis. Gastroenterology, 1999, Volume: 117, Issue:5 Topics: Animals; Carbon Tetrachloride; Cell Division; Cells, Cultured; Collagen; Extracellular Matrix; Immunosuppressive Agents; Liver; Liver Cirrhosis, Experimental; Male; Platelet-Derived Growth Factor; Procollagen; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sirolimus; Transforming Growth Factor beta; Transglutaminases	1999
Transforming growth factor-beta1 stimulates the synthesis of basement membrane proteins laminin, collagen type IV and entactin in rat liver sinusoidal endothelial cells. Journal of hepatology, 1999, Volume: 31, Issue:4 Topics: Animals; Basement Membrane; Blood Vessels; Blotting, Northern; Carbon Tetrachloride; Cells, Cultured; Collagen; Endothelium, Vascular; Extracellular Matrix Proteins; Gene Expression; Guinea Pigs; Immunologic Techniques; Laminin; Liver Circulation; Male; Membrane Glycoproteins; Rats; Rats, Wistar; RNA, Messenger; Transforming Growth Factor beta	1999
Glutathione levels discriminate between oxidative stress and transforming growth factor-beta signaling in activated rat hepatic stellate cells. The Journal of biological chemistry, 1999, Nov-26, Volume: 274, Issue:48 Topics: Acetylcysteine; Animals; Blotting, Northern; Carbon Tetrachloride; Catalase; Dose-Response Relationship, Drug; Glutathione; Glutathione Peroxidase; Hydrogen Peroxide; Liver; Male; Oxidative Stress; Rats; Rats, Wistar; RNA, Messenger; Signal Transduction; Superoxide Dismutase; Transforming Growth Factor beta; Vitamin K	1999
Inhibition of experimental liver cirrhosis in mice by telomerase gene delivery. Science (New York, N.Y.), 2000, Feb-18, Volume: 287, Issue:5456 Topics: Adenoviridae; Animals; Apoptosis; Carbon Tetrachloride; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Hepatectomy; Liver; Liver Cirrhosis, Experimental; Liver Regeneration; Mice; Mice, Knockout; Mice, Transgenic; Mitosis; Spleen; Telomerase; Telomere; Transforming Growth Factor beta	2000
Hepatic regeneration and TGF-beta: growing to a prosperous perfection. Gut, 2000, Volume: 46, Issue:5 Topics: Animals; Carbon Tetrachloride; Cell Division; Gene Expression; Humans; Liver; Liver Cirrhosis, Experimental; Liver Regeneration; Rats; Receptors, Transforming Growth Factor beta; RNA, Messenger; Transforming Growth Factor beta	2000
Modulation of transforming growth factor beta function in hepatocytes and hepatic stellate cells in rat liver injury. Gut, 2000, Volume: 46, Issue:5 Topics: Animals; Carbon Tetrachloride; Cell Division; DNA; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Fibronectins; Iodine Radioisotopes; Liver; Liver Regeneration; Male; Rats; Rats, Wistar; Receptors, Transforming Growth Factor beta; RNA, Messenger; Time Factors; Transforming Growth Factor beta	2000
The sympathetic nervous system promotes carbon tetrachloride-induced liver cirrhosis in rats by suppressing apoptosis and enhancing the growth kinetics of regenerating hepatocytes. Journal of gastroenterology, 2001, Volume: 36, Issue:2 Topics: Animals; Apoptosis; Carbon Tetrachloride; Carcinoma, Hepatocellular; Cell Division; Hepatocytes; Immunohistochemistry; Liver Cirrhosis; Liver Regeneration; Male; Models, Animal; Norepinephrine; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sympathectomy; Sympathetic Nervous System; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Cells, Cultured	2001
Rat hepatic stellate cells contribute to the acute-phase response with increased expression of alpha1(I) and alpha1(IV) collagens, tissue inhibitor of metalloproteinase-1, and matrix-metalloproteinase-2 messenger RNAs. Hepatology (Baltimore, Md.), 2001, Volume: 33, Issue:3 Topics: Acute-Phase Reaction; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Collagen; Interleukin-6; Irritants; Liver; Liver Diseases; Male; Matrix Metalloproteinase 2; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; RNA, Messenger; Time Factors; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha; Turpentine	2001
Carbon tetrachloride-induced acute liver injury in Mini and Wistar rats. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2001, Volume: 53, Issue:1 Topics: Alkaline Phosphatase; Animals; Animals, Genetically Modified; Apoptosis; Aspartate Aminotransferases; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cell Count; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Hepatocyte Growth Factor; Hepatocytes; Immunoenzyme Techniques; In Situ Nick-End Labeling; Liver; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Species Specificity; Transforming Growth Factor beta	2001
Attenuation of CCl(4)-induced hepatic fibrosis by GdCl(3) treatment or dietary glycine. American journal of physiology. Gastrointestinal and liver physiology, 2001, Volume: 281, Issue:1 Topics: Actins; Animals; Anti-Inflammatory Agents; Carbon Tetrachloride; Collagen; Endotoxins; Gadolinium; Gene Expression; Glycine; Kupffer Cells; Liver; Liver Cirrhosis; Male; Nitrophenols; Rats; Rats, Wistar; RNA, Messenger; Transforming Growth Factor beta	2001
The role of Smad3 in mediating mouse hepatic stellate cell activation. Hepatology (Baltimore, Md.), 2001, Volume: 34, Issue:1 Topics: Actins; Animals; Carbon Tetrachloride; Cattle; Cell Division; Cells, Cultured; Chemical and Drug Induced Liver Injury; Collagen; DNA; DNA-Binding Proteins; Enzyme Activation; Fetal Blood; Hepatocytes; In Situ Hybridization; Liver Diseases; Mice; Mice, Knockout; Mitogen-Activated Protein Kinases; Muscle, Smooth; Platelet-Derived Growth Factor; RNA, Messenger; Smad3 Protein; Trans-Activators; Transforming Growth Factor beta	2001
Differential regulation of TGF-beta signal in hepatic stellate cells between acute and chronic rat liver injury. Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1 Topics: Acute Disease; Animals; Carbon Tetrachloride; Cell Division; Cell Line; Cells, Cultured; Chemical and Drug Induced Liver Injury; Chronic Disease; Collagen; Collagen Type I; DNA-Binding Proteins; Fibroblasts; Gene Expression; Hepatocytes; Liver; Liver Diseases; Male; Phosphorylation; Plasminogen Activator Inhibitor 1; Promoter Regions, Genetic; Rats; Rats, Wistar; RNA, Messenger; Signal Transduction; Smad2 Protein; Smad7 Protein; Trans-Activators; Transfection; Transforming Growth Factor beta	2002
[Experimental study of the therapeutic effect of interferon-alpha on liver fibrosis]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2002, Volume: 10, Issue:1 Topics: Animals; Carbon Tetrachloride; Collagen Type IV; Disease Models, Animal; Hyaluronic Acid; Inflammation; Interferon-alpha; Laminin; Liver Cirrhosis; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta	2002
Accelerated reversal of carbon tetrachloride-induced cirrhosis in rats by the endothelin receptor antagonist TAK-044. Journal of gastroenterology and hepatology, 2002, Volume: 17, Issue:5 Topics: Animals; Arteries; Blood Pressure; Carbon Tetrachloride; Collagen; Collagenases; Endothelin Receptor Antagonists; Endothelin-1; Hydroxyproline; Liver; Liver Cirrhosis; Male; Peptides, Cyclic; Portal Vein; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptors, Endothelin; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1	2002
Leptin is essential for the hepatic fibrogenic response to chronic liver injury. Journal of hepatology, 2002, Volume: 37, Issue:2 Topics: Animals; Carbon Tetrachloride; Chronic Disease; Disease Progression; Fatty Liver; Female; Leptin; Liver Cirrhosis; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Oxidative Stress; Phenotype; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha	2002
Acute liver CCl(4) intoxication causes low HSP70 gene expression and a delayed transition through the cell cycle in aged rats. Experimental gerontology, 2002, Volume: 37, Issue:6 Topics: Aging; Alanine Transaminase; Albumins; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cell Cycle; Gene Expression; Glutathione; Hepatocyte Growth Factor; HSP70 Heat-Shock Proteins; Liver; Male; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-myc; Rats; Rats, Sprague-Dawley; Transforming Growth Factor alpha; Transforming Growth Factor beta; Transforming Growth Factor beta1	2002
Estrogen reduces CCL4- induced liver fibrosis in rats. World journal of gastroenterology, 2002, Volume: 8, Issue:5 Topics: Actins; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Biomarkers; Carbon Tetrachloride; Collagen Type I; Estrogen Antagonists; Estrogens; Female; Liver; Liver Cirrhosis; Male; Platelet-Derived Growth Factor; Rats; Rats, Sprague-Dawley; Tamoxifen; Transforming Growth Factor beta; Transforming Growth Factor beta1	2002
[Green tea extracts protected against carbon tetrachloride-induced chronic liver damage and cirrhosis]. Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 2002, Volume: 36, Issue:4 Topics: Animals; Carbon Tetrachloride; Chronic Disease; Liver; Liver Cirrhosis; Male; Malondialdehyde; Plant Extracts; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tea; Transforming Growth Factor beta; Transforming Growth Factor beta1	2002
Massive hepatic apoptosis associated with TGF-beta1 activation after Fas ligand treatment of IGF binding protein-1-deficient mice. The Journal of clinical investigation, 2003, Volume: 111, Issue:1 Topics: Animals; Apoptosis; Carbon Tetrachloride; Caspase 3; Caspase 8; Caspase 9; Caspases; Cell Differentiation; Enzyme Activation; Fas Ligand Protein; fas Receptor; Fibronectins; Hepatocytes; Immunohistochemistry; In Situ Nick-End Labeling; Insulin-Like Growth Factor Binding Protein 1; Integrins; Liver; Matrix Metalloproteinase 9; Membrane Glycoproteins; Mice; Mice, Transgenic; Models, Biological; Models, Genetic; Signal Transduction; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1; Up-Regulation	2003
Influence of leptin in the development of hepatic fibrosis produced in mice by Schistosoma mansoni infection and by chronic carbon tetrachloride administration. Journal of hepatology, 2003, Volume: 38, Issue:3 Topics: Animals; Carbon Tetrachloride; Cytokines; Drug Administration Schedule; Leptin; Liver; Liver Cirrhosis, Experimental; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Obesity; Schistosomiasis mansoni; Spleen; Transforming Growth Factor beta; Transforming Growth Factor beta1	2003
Leptin induces increased alpha2(I) collagen gene expression in cultured rat hepatic stellate cells. Journal of cellular biochemistry, 2003, May-15, Volume: 89, Issue:2 Topics: Alanine Transaminase; Animals; Carbon Tetrachloride; Cells, Cultured; Collagen; Collagen Type I; Cycloheximide; Dactinomycin; Electrophoretic Mobility Shift Assay; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Leptin; Liver; Male; Mice; Promoter Regions, Genetic; Protein Synthesis Inhibitors; Rats; RNA, Messenger; Transforming Growth Factor beta	2003
Effect of compound rhodiola sachalinensis A Bor on CCl4-induced liver fibrosis in rats and its probable molecular mechanisms. World journal of gastroenterology, 2003, Volume: 9, Issue:7 Topics: Animals; Biomarkers; Carbon Tetrachloride; Drugs, Chinese Herbal; Gene Expression; Liver; Liver Cirrhosis; Male; Plant Preparations; Rats; Rats, Sprague-Dawley; Rhodiola; RNA, Messenger; Sodium-Calcium Exchanger; Transforming Growth Factor beta; Transforming Growth Factor beta1	2003
[Therapeutic effects of octreotide on hepatofibrosis-induced with carbon tetrachloride in rats]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2003, Volume: 11, Issue:7 Topics: Actins; Animals; Carbon Tetrachloride; Collagen Type I; Collagen Type III; Hyaluronic Acid; Laminin; Liver; Liver Cirrhosis, Experimental; Male; Octreotide; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1	2003
AT1A-deficient mice show less severe progression of liver fibrosis induced by CCl(4). Biochemical and biophysical research communications, 2003, Aug-15, Volume: 308, Issue:1 Topics: Animals; Base Sequence; Carbon Tetrachloride; DNA Primers; Enzyme-Linked Immunosorbent Assay; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Mice; Mice, Knockout; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha	2003
A synthetic peptide from transforming growth factor beta type III receptor inhibits liver fibrogenesis in rats with carbon tetrachloride liver injury. Cytokine, 2003, Volume: 22, Issue:1-2 Topics: Amino Acid Sequence; Animals; Carbon Tetrachloride; Liver Cirrhosis, Experimental; Molecular Sequence Data; Peptides; Proteoglycans; Rats; Receptors, Transforming Growth Factor beta; Transcriptional Activation; Transforming Growth Factor beta; Transforming Growth Factor beta1	2003
Therapeutic significance of Y-27632, a Rho-kinase inhibitor, on the established liver fibrosis. The Journal of surgical research, 2003, Volume: 114, Issue:1 Topics: Actins; Amides; Animals; Carbon Tetrachloride; Enzyme Inhibitors; Infusion Pumps, Implantable; Infusions, Parenteral; Intracellular Signaling Peptides and Proteins; Liver; Liver Cirrhosis, Experimental; Male; Models, Animal; Myocytes, Smooth Muscle; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Wistar; rho-Associated Kinases; Sodium-Calcium Exchanger; Transforming Growth Factor beta; Transforming Growth Factor beta1	2003
Role of fibroblast growth factor type 1 and 2 in carbon tetrachloride-induced hepatic injury and fibrogenesis. The American journal of pathology, 2003, Volume: 163, Issue:4 Topics: Actins; Animals; Bile Acids and Salts; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Collagen Type I; Drug Administration Schedule; Extracellular Matrix; Fibroblast Growth Factor 1; Fibroblast Growth Factor 2; Hepatectomy; Liver; Liver Cirrhosis; Liver Diseases; Liver Regeneration; Mice; Mice, Knockout; Muscle, Smooth; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1	2003
Reverse transformation of hepatic myofibroblast-like cells by TGFbeta1/LAP. Biochemical and biophysical research communications, 2003, Nov-28, Volume: 311, Issue:4 Topics: Animals; Carbon Tetrachloride; Cell Differentiation; Cell Line; Extracellular Matrix; Fibroblasts; Liver; Liver Cirrhosis; Male; Peptide Fragments; Protein Precursors; Rats; Rats, Wistar; Recombinant Proteins; Transforming Growth Factor beta; Transforming Growth Factor beta1	2003
Effects of cytokines on carbon tetrachloride-induced hepatic fibrogenesis in rats. World journal of gastroenterology, 2004, Volume: 10, Issue:1 Topics: Animals; Antineoplastic Agents; Carbon Tetrachloride; Cytokines; Disease Models, Animal; Interleukin-10; Interleukin-6; Liver Cirrhosis; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha	2004
Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectin. Gastroenterology, 2003, Volume: 125, Issue:6 Topics: Active Transport, Cell Nucleus; Adenoviridae; Adiponectin; Animals; Becaplermin; Carbon Tetrachloride; Cell Division; Cell Movement; Connective Tissue Growth Factor; DNA-Binding Proteins; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Liver; Liver Cirrhosis, Experimental; Male; Mice; Mice, Knockout; Platelet-Derived Growth Factor; Proteins; Proto-Oncogene Proteins c-sis; Receptors, Adiponectin; Receptors, Cell Surface; RNA, Messenger; Smad2 Protein; Trans-Activators; Transforming Growth Factor beta; Transforming Growth Factor beta1	2003
[Perindopril attenuates the progression of CCl4-inducing rat hepatic fibrosis]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2004, Volume: 12, Issue:1 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Becaplermin; Blotting, Western; Carbon Tetrachloride; Liver; Liver Cirrhosis, Experimental; Male; Perindopril; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Rats; Rats, Wistar; Transforming Growth Factor beta; Transforming Growth Factor beta1	2004
Modulation of fibronectin gene expression in inflammatory mononuclear phagocytes of rat liver after acute liver injury. Journal of hepatology, 2004, Volume: 40, Issue:4 Topics: Acute Disease; Animals; Carbon Tetrachloride; Dexamethasone; Fibronectins; Gene Expression; Immunohistochemistry; In Situ Hybridization; In Vitro Techniques; Interferon-gamma; Lipopolysaccharides; Liver; Phagocytes; Rats; Rats, Wistar; Recombinant Proteins; RNA, Messenger; Transforming Growth Factor beta	2004
Pitavastatin enhances the anti-fibrogenesis effects of candesartan, an angiotensin II receptor blocker, on CCl4-induced liver fibrosis in rats. Journal of UOEH, 2004, Jun-01, Volume: 26, Issue:2 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Carbon Tetrachloride; Depression, Chemical; Drug Synergism; Drug Therapy, Combination; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Liver Cirrhosis; Male; Quinolines; Rats; Rats, Sprague-Dawley; Tetrazoles; Transforming Growth Factor beta	2004
Systemic infusion of FLK1(+) mesenchymal stem cells ameliorate carbon tetrachloride-induced liver fibrosis in mice. Transplantation, 2004, Jul-15, Volume: 78, Issue:1 Topics: Actins; Animals; Carbon Tetrachloride; Cell Differentiation; Female; Liver Cirrhosis; Male; Mesoderm; Mice; Mice, Inbred BALB C; RNA, Messenger; Stem Cell Transplantation; Stem Cells; Transforming Growth Factor beta; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor Receptor-2	2004
[Obstruction of TGF-beta1 signal transduction can decrease the process of hepatocellular carcinoma in mice induced by CCl4/ethanol]. Zhonghua yi xue za zhi, 2004, Jul-02, Volume: 84, Issue:13 Topics: Adenoviridae; Animals; Antisense Elements (Genetics); Carbon Tetrachloride; Cell Transformation, Neoplastic; DNA-Binding Proteins; Ethanol; Liver Cirrhosis, Experimental; Liver Neoplasms, Experimental; Male; Mice; Random Allocation; Signal Transduction; Smad4 Protein; Trans-Activators; Transforming Growth Factor beta; Transforming Growth Factor beta1	2004
Effect of losartan, an angiotensin II antagonist, on hepatic fibrosis induced by CCl4 in rats. Digestive diseases and sciences, 2004, Volume: 49, Issue:10 Topics: Alanine Transaminase; Angiotensin II Type 1 Receptor Blockers; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Liver Cirrhosis; Losartan; Male; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha	2004
[The active metabolite of leflunomide A771726 inhibits proliferation and collagen synthesis of hepatic stellate cell]. Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2004, Volume: 33, Issue:6 Topics: Aniline Compounds; Animals; Carbon Tetrachloride; Cell Division; Cells, Cultured; Collagen Type I; Crotonates; Hepatocytes; Hydroxybutyrates; Immunosuppressive Agents; Interleukin-1; Isoxazoles; Kupffer Cells; Leflunomide; Male; Nitriles; Rats; Rats, Sprague-Dawley; Toluidines; Transforming Growth Factor beta	2004
Expression of insulin-like growth factor I by activated hepatic stellate cells reduces fibrogenesis and enhances regeneration after liver injury. Gut, 2005, Volume: 54, Issue:1 Topics: Actins; Adipocytes; Animals; Carbon Tetrachloride; Cells, Cultured; Collagen; Female; Fibronectins; Insulin-Like Growth Factor I; Liver Cirrhosis, Experimental; Liver Regeneration; Mice; Mice, Transgenic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1	2005
[Effects of perindopril and valsartan on the expression of TGF beta 1 and TGF beta receptor II mRNA, Smad3 and Smad7 in experimental hepatic fibrotic rats]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2004, Volume: 12, Issue:12 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Female; Liver Cirrhosis, Experimental; Male; Perindopril; Random Allocation; Rats; Rats, Wistar; Receptors, Transforming Growth Factor beta; RNA, Messenger; Smad3 Protein; Smad7 Protein; Tetrazoles; Transforming Growth Factor beta; Transforming Growth Factor beta1; Valine; Valsartan	2004
Alterations of mast cells and TGF-beta1 on the silymarin treatment for CCl(4)-induced hepatic fibrosis. World journal of gastroenterology, 2005, Feb-28, Volume: 11, Issue:8 Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Collagen; Immunohistochemistry; Liver; Liver Cirrhosis; Male; Mast Cells; Rats; Rats, Wistar; Silymarin; Transforming Growth Factor beta; Transforming Growth Factor beta1	2005
Lack of tumor necrosis factor receptor type 1 inhibits liver fibrosis induced by carbon tetrachloride in mice. Cytokine, 2005, Mar-07, Volume: 29, Issue:5 Topics: Animals; Carbon Tetrachloride; Gene Deletion; Intercellular Adhesion Molecule-1; Interleukin-6; Liver Cirrhosis; Mice; Mice, Knockout; Procollagen; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; RNA, Messenger; Transcription Factors; Transforming Growth Factor beta; Transforming Growth Factor beta2; Vascular Cell Adhesion Molecule-1	2005
Taurine inhibits oxidative damage and prevents fibrosis in carbon tetrachloride-induced hepatic fibrosis. Journal of hepatology, 2005, Volume: 43, Issue:1 Topics: Actins; Animals; Carbon Tetrachloride; Cells, Cultured; Dose-Response Relationship, Drug; Hydroxyproline; Immunohistochemistry; Lipid Peroxides; Liver; Liver Cirrhosis, Experimental; Male; Myocytes, Smooth Muscle; Osmolar Concentration; Oxidative Stress; Rats; Rats, Sprague-Dawley; RNA, Messenger; Taurine; Transforming Growth Factor beta; Transforming Growth Factor beta1	2005
S-adenosylmethionine blocks collagen I production by preventing transforming growth factor-beta induction of the COL1A2 promoter. The Journal of biological chemistry, 2005, Sep-02, Volume: 280, Issue:35 Topics: Animals; Base Sequence; Carbon Tetrachloride; Cells, Cultured; Collagen; Collagen Type I; Cytochrome P-450 CYP2E1; Fibrosis; Gene Expression Regulation; Genes, Reporter; Glutathione; Hepatocytes; Humans; Lipid Peroxidation; Liver; Mice; Mice, Transgenic; Molecular Sequence Data; Promoter Regions, Genetic; S-Adenosylmethionine; Transforming Growth Factor beta	2005
Cell type-specific intervention of transforming growth factor beta/Smad signaling suppresses collagen gene expression and hepatic fibrosis in mice. Gastroenterology, 2005, Volume: 129, Issue:1 Topics: Adenoviridae; Animals; Carbon Tetrachloride; Collagen; Collagen Type I; DNA-Binding Proteins; Enhancer Elements, Genetic; Gene Expression; Genetic Therapy; Green Fluorescent Proteins; Interferon-gamma; Liver Cirrhosis; Mice; Mice, Transgenic; Nuclear Proteins; Promoter Regions, Genetic; Rats; Signal Transduction; Smad Proteins; Trans-Activators; Transforming Growth Factor beta; Y-Box-Binding Protein 1	2005
F2-isoprostanes stimulate collagen synthesis in activated hepatic stellate cells: a link with liver fibrosis? Laboratory investigation; a journal of technical methods and pathology, 2005, Volume: 85, Issue:11 Topics: Animals; Carbon Tetrachloride; Cell Proliferation; Cells, Cultured; Collagen; DNA; Dose-Response Relationship, Drug; F2-Isoprostanes; Fibrosis; Hepatocytes; Humans; Injections, Intraperitoneal; Liver; Liver Cirrhosis, Experimental; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta; Transforming Growth Factor beta1; U937 Cells	2005
Ginkgo biloba extract alleviates liver fibrosis induced by CCl in rats. Liver international : official journal of the International Association for the Study of the Liver, 2005, Volume: 25, Issue:6 Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Collagen Type I; Ginkgo biloba; Growth Substances; Hepatocytes; Immunohistochemistry; Liver; Liver Cirrhosis, Experimental; Male; Malondialdehyde; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Transforming Growth Factor beta; Transforming Growth Factor beta1	2005
[Effects of nuclear factor kappaB and transforming growth factor beta1 in the anti-liver fibrosis process using Ginkgo biloba extract]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2005, Volume: 13, Issue:12 Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Drugs, Chinese Herbal; Ginkgo biloba; Liver Cirrhosis, Experimental; Male; NF-kappa B; Phytotherapy; Plant Leaves; Rats; Rats, Wistar; Transforming Growth Factor beta	2005
Ameliorative effect of Ganoderma lucidum on carbon tetrachloride-induced liver fibrosis in rats. World journal of gastroenterology, 2006, Jan-14, Volume: 12, Issue:2 Topics: Animals; Body Weight; Carbon Tetrachloride; Liver; Liver Cirrhosis, Experimental; Male; Methionine Adenosyltransferase; Organ Size; Plant Extracts; Rats; Rats, Wistar; Reishi; Transforming Growth Factor beta; Transforming Growth Factor beta1	2006
Early induction of TGF-beta1 through a fasting-re-feeding regimen promotes liver carcinogenesis by a sub-initiating dose of diethylnitrosamine. Cell proliferation, 2006, Volume: 39, Issue:2 Topics: 2-Acetylaminofluorene; Animals; Apoptosis; bcl-2-Associated X Protein; Carbon Tetrachloride; Carcinogens; Diethylnitrosamine; Eating; Fasting; Liver Cirrhosis, Experimental; Liver Neoplasms, Experimental; Male; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Inbred F344; Transforming Growth Factor beta; Transforming Growth Factor beta1; Up-Regulation	2006
Galectin-3 regulates myofibroblast activation and hepatic fibrosis. Proceedings of the National Academy of Sciences of the United States of America, 2006, Mar-28, Volume: 103, Issue:13 Topics: Animals; Carbon Tetrachloride; Fibroblasts; Galectin 3; Humans; Inflammation; Liver; Liver Cirrhosis; Liver Cirrhosis, Experimental; Mice; Mice, Knockout; Muscle Cells; Rats; RNA, Small Interfering; Signal Transduction; Smad Proteins; Transforming Growth Factor beta; Up-Regulation	2006
Amelioration of liver fibrogenesis by dual inhibition of PDGF and TGF-beta with a combination of imatinib mesylate and ACE inhibitor in rats. International journal of molecular medicine, 2006, Volume: 17, Issue:5 Topics: Actins; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzamides; Carbon Tetrachloride; Drug Synergism; Drug Therapy, Combination; Imatinib Mesylate; Immunohistochemistry; Liver; Liver Cirrhosis, Experimental; Male; Muscle, Smooth; Phosphorylation; Piperazines; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Pyrimidines; Rats; Rats, Inbred F344; Receptors, Platelet-Derived Growth Factor; Severity of Illness Index; Transforming Growth Factor beta	2006
Adeno-associated virus-mediated heme oxygenase-1 gene transfer suppresses the progression of micronodular cirrhosis in rats. World journal of gastroenterology, 2006, Apr-07, Volume: 12, Issue:13 Topics: Animals; Carbon Tetrachloride; Dependovirus; Gene Transfer, Horizontal; Genetic Therapy; Heme Oxygenase-1; Liver; Liver Cirrhosis, Experimental; Rats; Rats, Inbred Lew; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1	2006
S-allyl cysteine attenuated CCl4-induced oxidative stress and pulmonary fibrosis in rats. BioFactors (Oxford, England), 2006, Volume: 26, Issue:1 Topics: Animals; Bronchoalveolar Lavage Fluid; Carbon Tetrachloride; Cysteine; Enzyme Precursors; Glutathione; Hydroxyproline; Liver; Lung; Male; Matrix Metalloproteinase 9; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Pulmonary Fibrosis; Rats; Rats, Wistar; Reactive Oxygen Species; Sulfhydryl Compounds; Transforming Growth Factor beta; Transforming Growth Factor beta1	2006
Inhibition of connective tissue growth factor by siRNA prevents liver fibrosis in rats. The journal of gene medicine, 2006, Volume: 8, Issue:7 Topics: Animals; Base Sequence; Carbon Tetrachloride; Connective Tissue Growth Factor; Gene Expression; Gene Silencing; Immediate-Early Proteins; Injections, Intravenous; Intercellular Signaling Peptides and Proteins; Liver; Liver Cirrhosis; Male; Portal Vein; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Smad2 Protein; Smad7 Protein; Transforming Growth Factor beta; Transforming Growth Factor beta1	2006
Relationship between transforming growth factor beta1 and anti-fibrotic effect of interleukin-10. World journal of gastroenterology, 2006, Apr-21, Volume: 12, Issue:15 Topics: Animals; Base Sequence; Carbon Tetrachloride; Gene Expression; Immunohistochemistry; Interleukin-10; Liver Cirrhosis; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1	2006
Filtrate of fermented mycelia from Antrodia camphorata reduces liver fibrosis induced by carbon tetrachloride in rats. World journal of gastroenterology, 2006, Apr-21, Volume: 12, Issue:15 Topics: Animals; Base Sequence; Carbon Tetrachloride; Collagen Type I; Fermentation; Hydroxyproline; Liver Cirrhosis; Male; Malondialdehyde; Polyporales; Rats; Rats, Wistar; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta; Transforming Growth Factor beta1	2006
Anti-fibrogenic function of angiotensin II type 2 receptor in CCl4-induced liver fibrosis. Biochemical and biophysical research communications, 2006, Aug-04, Volume: 346, Issue:3 Topics: Animals; Carbon Tetrachloride; Gene Expression Regulation; Hydroxyproline; Inflammation; Liver Cirrhosis; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Thiobarbituric Acid Reactive Substances; Transforming Growth Factor beta	2006
Effects of extract from Ginkgo biloba on carbon tetrachloride-induced liver injury in rats. World journal of gastroenterology, 2006, Jun-28, Volume: 12, Issue:24 Topics: Actins; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Collagen Type I; Collagen Type III; Collagen Type IV; Ginkgo biloba; Glutathione Peroxidase; Hyaluronic Acid; Immunohistochemistry; Liver; Liver Cirrhosis; Male; Plant Extracts; Random Allocation; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Transforming Growth Factor beta; Transforming Growth Factor beta1	2006
Resveratrol prevents fibrosis, NF-kappaB activation and TGF-beta increases induced by chronic CCl4 treatment in rats. Journal of applied toxicology : JAT, 2008, Volume: 28, Issue:1 Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Bilirubin; Carbon Tetrachloride; Glutathione; Glutathione Disulfide; Glycogen; Lipid Peroxidation; Liver; Liver Cirrhosis, Experimental; Male; NF-kappa B; Protective Agents; Rats; Rats, Wistar; Resveratrol; Stilbenes; Transforming Growth Factor beta	2008
Selective inactivation of NF-kappaB in the liver using NF-kappaB decoy suppresses CCl4-induced liver injury and fibrosis. American journal of physiology. Gastrointestinal and liver physiology, 2007, Volume: 293, Issue:3 Topics: Actins; Active Transport, Cell Nucleus; Animals; Anti-Inflammatory Agents; Apoptosis; Carbon Tetrachloride; Cell Nucleus; Cells, Cultured; Chemical and Drug Induced Liver Injury; Collagen Type I; Cytokines; Disease Models, Animal; Gene Transfer Techniques; Genetic Therapy; Hydrogen Peroxide; Kupffer Cells; Liposomes; Liver; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Oligonucleotides; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sendai virus; Time Factors; Transfection; Transforming Growth Factor beta	2007
Disruption of the Smad7 gene enhances CCI4-dependent liver damage and fibrogenesis in mice. Journal of cellular and molecular medicine, 2008, Volume: 12, Issue:5B Topics: Actins; Animals; Apoptosis; Carbon Tetrachloride; Collagen; Disease Models, Animal; Fibrosis; Genes, Reporter; Immunohistochemistry; Inflammation; Liver Cirrhosis; Liver Diseases; Luciferases; Mice; Mice, Mutant Strains; Phosphorylation; Recombinant Proteins; Signal Transduction; Smad2 Protein; Smad7 Protein; Transforming Growth Factor beta; Up-Regulation	2008
Effect of Oxymatrine on the TGFbeta-Smad signaling pathway in rats with CCl4-induced hepatic fibrosis. World journal of gastroenterology, 2008, Apr-07, Volume: 14, Issue:13 Topics: Alkaloids; Animals; Antiviral Agents; Carbon Tetrachloride; CREB-Binding Protein; Liver Cirrhosis; Male; Models, Biological; Quinolizines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Smad Proteins; Smad3 Protein; Smad7 Protein; Transforming Growth Factor beta	2008
Decrease of PECAM-1-gene-expression induced by proinflammatory cytokines IFN-gamma and IFN-alpha is reversed by TGF-beta in sinusoidal endothelial cells and hepatic mononuclear phagocytes. BMC physiology, 2008, May-08, Volume: 8 Topics: Animals; Carbon Tetrachloride; Cells, Cultured; Chemical and Drug Induced Liver Injury; Cytokines; Down-Regulation; Endothelial Cells; Gene Expression Regulation; Immunologic Factors; Interferon-alpha; Interferon-gamma; Liver; Male; Mononuclear Phagocyte System; Rats; Rats, Wistar; Transforming Growth Factor beta	2008
Enhanced actions of insulin-like growth factor-I and interferon-alpha co-administration in experimental cirrhosis. Liver international : official journal of the International Association for the Study of the Liver, 2009, Volume: 29, Issue:1 Topics: Animals; Carbon Tetrachloride; Drug Therapy, Combination; Insulin-Like Growth Factor I; Interferon-alpha; Lipid Peroxidation; Liver; Liver Cirrhosis, Experimental; Oligonucleotides; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Serum Albumin; Statistics, Nonparametric; Transforming Growth Factor beta	2009
Hepatocyte-specific Smad7 expression attenuates TGF-beta-mediated fibrogenesis and protects against liver damage. Gastroenterology, 2008, Volume: 135, Issue:2 Topics: Animals; Apoptosis; Carbon Tetrachloride; Cell Line; Cell Survival; Cell Transdifferentiation; Cells, Cultured; Collagen; Disease Models, Animal; Gene Expression Profiling; Hepatitis B; Hepatocytes; Humans; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oligonucleotide Array Sequence Analysis; Phenotype; Schistosomiasis; Smad7 Protein; Time Factors; Transforming Growth Factor beta	2008
Platelets contribute to the reduction of liver fibrosis in mice. Journal of gastroenterology and hepatology, 2009, Volume: 24, Issue:1 Topics: Animals; Blood Platelets; Carbon Tetrachloride; Cell Proliferation; Disease Models, Animal; Female; Gene Expression Regulation; Hydroxyproline; Liver; Liver Cirrhosis; Liver Regeneration; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitotic Index; Phosphorylation; Platelet Count; Proto-Oncogene Proteins c-akt; RNA, Messenger; Splenectomy; Thrombocytosis; Thrombopoietin; Transforming Growth Factor beta	2009
Methyl palmitate prevents CCl(4)-induced liver fibrosis. Journal of applied toxicology : JAT, 2008, Volume: 28, Issue:8 Topics: Animals; Biotransformation; Blotting, Western; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Collagen; Down-Regulation; Histocytochemistry; Lipid Peroxidation; Liver Cirrhosis; Male; Necrosis; Palmitates; Rats; Rats, Wistar; Transforming Growth Factor beta	2008
Potent antioxidant role of pirfenidone in experimental cirrhosis. European journal of pharmacology, 2008, Oct-24, Volume: 595, Issue:1-3 Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Bilirubin; Carbon Tetrachloride; Catalase; Collagen Type I; Common Bile Duct; Hepatocyte Growth Factor; Ligation; Liver; Liver Cirrhosis, Experimental; Malondialdehyde; NF-kappa B; Nitric Oxide Synthase Type II; Nitrites; Onium Compounds; Oxidative Stress; Proto-Oncogene Proteins c-met; Pyridones; Rats; Rats, Wistar; Superoxide Dismutase; Transforming Growth Factor beta	2008
Curcumin prevents and reverses cirrhosis induced by bile duct obstruction or CCl4 in rats: role of TGF-beta modulation and oxidative stress. Fundamental & clinical pharmacology, 2008, Volume: 22, Issue:4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cholestasis; Curcumin; Dose-Response Relationship, Drug; Drug Interactions; Liver Cirrhosis, Experimental; Male; Oxidative Stress; Rats; Rats, Wistar; Transforming Growth Factor beta	2008
Murine cirrhosis induces hepatocyte epithelial mesenchymal transition and alterations in survival signaling pathways. Hepatology (Baltimore, Md.), 2008, Volume: 48, Issue:3 Topics: Animals; Carbon Tetrachloride; Cell Survival; Cell Transdifferentiation; Cells, Cultured; Collagen Type I; Epithelial Cells; Hepatocytes; Liver; Liver Cirrhosis; Male; Mesoderm; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinase Kinases; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Smad Proteins; Transforming Growth Factor beta; Vimentin	2008
Divergent transforming growth factor-beta signaling in hepatic stellate cells after liver injury: functional effects on ECE-1 regulation. The American journal of pathology, 2008, Volume: 173, Issue:3 Topics: Animals; Aspartic Acid Endopeptidases; Bile Ducts; Carbon Tetrachloride; Cells, Cultured; Electrophoretic Mobility Shift Assay; Endothelin-Converting Enzymes; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Hepatocytes; Humans; Immunoblotting; Immunohistochemistry; Immunoprecipitation; Ligation; Liver; Liver Diseases; Metalloendopeptidases; Rats; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta	2008
Inhibition of plasminogen activator inhibitor-1 expression by siRNA in rat hepatic stellate cells. Journal of gastroenterology and hepatology, 2008, Volume: 23, Issue:12 Topics: Actins; Animals; Carbon Tetrachloride; Cell Line; Cell Proliferation; Collagen Type I; Collagen Type III; Disease Models, Animal; Down-Regulation; Hepatic Stellate Cells; Liver; Liver Cirrhosis, Experimental; Male; Plasminogen Activator Inhibitor 1; Rats; Rats, Sprague-Dawley; RNA Interference; RNA, Messenger; RNA, Small Interfering; Time Factors; Tissue Inhibitor of Metalloproteinase-1; Transfection; Transforming Growth Factor beta	2008
Trolox down-regulates transforming growth factor-beta and prevents experimental cirrhosis. Basic & clinical pharmacology & toxicology, 2008, Volume: 103, Issue:5 Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidants; Blotting, Western; Carbon Tetrachloride; Chromans; Down-Regulation; gamma-Glutamyltransferase; Glutathione; Glycogen; Hydroxyproline; Lipid Peroxidation; Liver Cirrhosis, Experimental; Male; Rats; Rats, Wistar; Transforming Growth Factor beta	2008
Cathepsins B and D drive hepatic stellate cell proliferation and promote their fibrogenic potential. Hepatology (Baltimore, Md.), 2009, Volume: 49, Issue:4 Topics: Actins; Animals; Carbon Tetrachloride; Cathepsin B; Cathepsin D; Cell Line; Cell Proliferation; Cell Transdifferentiation; Down-Regulation; Gene Expression; Gene Silencing; Hepatic Stellate Cells; Humans; Liver Cirrhosis; Mice; Mice, Inbred C57BL; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Transforming Growth Factor beta; Up-Regulation	2009
Reactive nitrogen species switch on early extracellular matrix remodeling via induction of MMP1 and TNFalpha. Gastroenterology, 2009, Volume: 136, Issue:4 Topics: Actins; Animals; Apoptosis; Carbon Tetrachloride; Cell Line; Cell Proliferation; Cells, Cultured; Collagen; Collagen Type I; Collagen Type I, alpha 1 Chain; Disease Models, Animal; Extracellular Matrix; Female; Humans; Liver; Liver Cirrhosis; Matrix Metalloproteinase 1; Molsidomine; Nitric Oxide Donors; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Reactive Nitrogen Species; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha	2009
Loss of STAT5 causes liver fibrosis and cancer development through increased TGF-{beta} and STAT3 activation. The Journal of experimental medicine, 2009, Apr-13, Volume: 206, Issue:4 Topics: Animals; Carbon Tetrachloride; Disease Progression; Fibrinogens, Abnormal; Gene Deletion; Haptoglobins; Hepatocytes; Liver; Liver Cirrhosis; Liver Neoplasms; Mice; Mice, Knockout; STAT3 Transcription Factor; STAT5 Transcription Factor; Transforming Growth Factor beta	2009
Inflammasome-mediated regulation of hepatic stellate cells. American journal of physiology. Gastrointestinal and liver physiology, 2009, Volume: 296, Issue:6 Topics: Actins; Animals; Apoptosis Regulatory Proteins; Calcium Signaling; Carbon Tetrachloride; CARD Signaling Adaptor Proteins; Carrier Proteins; Cell Line, Transformed; Chemotaxis; Collagen Type I; Cytoskeletal Proteins; Gene Expression; Hepatic Stellate Cells; Humans; Inflammation; Inositol 1,4,5-Trisphosphate; Liver; Liver Cirrhosis; Mice; Mice, Inbred C57BL; Mice, Knockout; NLR Family, Pyrin Domain-Containing 3 Protein; Platelet-Derived Growth Factor; Thioacetamide; Transforming Growth Factor beta; Uric Acid	2009
N-acetylcysteine prevents carbon tetrachloride-induced liver cirrhosis: role of liver transforming growth factor-beta and oxidative stress. European journal of gastroenterology & hepatology, 2009, Volume: 21, Issue:8 Topics: Acetylcysteine; Animals; Antioxidants; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Liver Cirrhosis, Experimental; Male; Oxidative Stress; Rats; Rats, Wistar; Transforming Growth Factor beta	2009
[Effects of transforming growth factor beta 3 on the histopathology and expression of collagen I in experimental hepatic fibrotic rats]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2009, Volume: 17, Issue:6 Topics: Animals; Carbon Tetrachloride; Collagen Type I; Dependovirus; Disease Models, Animal; Genetic Therapy; Genetic Vectors; Immunohistochemistry; Liver; Liver Cirrhosis, Experimental; Male; Random Allocation; Rats; Rats, Sprague-Dawley; Transfection; Transforming Growth Factor beta	2009
Thymus cell antigen-1-expressing cells in the oval cell compartment. Hepatology (Baltimore, Md.), 2009, Volume: 50, Issue:2 Topics: Actins; Animals; Carbon Tetrachloride; Cells, Cultured; Desmin; Extracellular Matrix; Gene Expression; Intercellular Signaling Peptides and Proteins; Liver; Liver Regeneration; Male; Rats; Rats, Inbred F344; Thy-1 Antigens; Transforming Growth Factor beta	2009
Upregulation of hepatoma-derived growth factor is involved in murine hepatic fibrogenesis. Journal of hepatology, 2010, Volume: 52, Issue:1 Topics: Animals; Carbon Tetrachloride; Cells, Cultured; Disease Models, Animal; Hepatocytes; Intercellular Signaling Peptides and Proteins; Ligation; Liver Cirrhosis; Male; Mice; Mice, Inbred ICR; Rats; Rats, Sprague-Dawley; Signal Transduction; Transforming Growth Factor beta; Up-Regulation	2010
Transplantation of human amnion epithelial cells reduces hepatic fibrosis in immunocompetent CCl₄-treated mice. Cell transplantation, 2010, Volume: 19, Issue:9 Topics: Amnion; Animals; Apoptosis; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cell Separation; Cell Transplantation; Epithelial Cells; Female; Humans; Immunohistochemistry; Liver; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Pregnancy; Transforming Growth Factor beta; Transplantation, Heterologous	2010
Antifibrotic and fibrolytic properties of celecoxib in liver damage induced by carbon tetrachloride in the rat. Liver international : official journal of the International Association for the Study of the Liver, 2010, Volume: 30, Issue:7 Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Antioxidants; Aspartate Aminotransferases; Carbon Tetrachloride; Celecoxib; Chemical and Drug Induced Liver Injury; Collagen; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; gamma-Glutamyltransferase; Glutathione; Glycogen; Liver; Liver Cirrhosis; Male; Malondialdehyde; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Pyrazoles; Rats; Rats, Wistar; Sulfonamides; Time Factors; Transforming Growth Factor beta	2010
Anti-fibrotic effect of chorionic plate-derived mesenchymal stem cells isolated from human placenta in a rat model of CCl(4)-injured liver: potential application to the treatment of hepatic diseases. Journal of cellular biochemistry, 2010, Dec-15, Volume: 111, Issue:6 Topics: Animals; Blotting, Western; Carbon Tetrachloride; Cell Differentiation; Cell Line; Cells, Cultured; Chemical and Drug Induced Liver Injury; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Humans; Liver Diseases; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Placenta; Pregnancy; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Transforming Growth Factor beta	2010
A novel small compound that promotes nuclear translocation of YB-1 ameliorates experimental hepatic fibrosis in mice. The Journal of biological chemistry, 2011, Feb-11, Volume: 286, Issue:6 Topics: Active Transport, Cell Nucleus; Alkadienes; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cell Nucleus; Collagen; DNA-Binding Proteins; Gene Expression Regulation; Humans; Liver Cirrhosis, Experimental; Mice; Nuclear Proteins; Poly(A)-Binding Proteins; Protein Binding; Protein Structure, Tertiary; Rats; Signal Transduction; Smad3 Protein; Transcription Factors; Transforming Growth Factor beta; Y-Box-Binding Protein 1	2011
Inhibition of PDGF, TGF-β, and Abl signaling and reduction of liver fibrosis by the small molecule Bcr-Abl tyrosine kinase antagonist Nilotinib. Journal of hepatology, 2011, Volume: 55, Issue:3 Topics: Actins; Animals; Apoptosis; Bile Ducts; Carbon Tetrachloride; Cell Proliferation; Collagen; G1 Phase Cell Cycle Checkpoints; Genes, abl; Hepatic Stellate Cells; Hepatocytes; Humans; Ligation; Liver Cirrhosis; Male; Mice; Mice, Inbred BALB C; Platelet-Derived Growth Factor; PPAR gamma; Protein-Tyrosine Kinases; Pyrimidines; Receptors, TNF-Related Apoptosis-Inducing Ligand; Signal Transduction; Transforming Growth Factor beta	2011
N-methyl-4-isoleucine cyclosporine attenuates CCl -induced liver fibrosis in rats by interacting with cyclophilin B and D. Journal of gastroenterology and hepatology, 2011, Volume: 26, Issue:3 Topics: Actins; Alanine Transaminase; Analysis of Variance; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Cell Line; Collagen Type III; Cyclophilins; Cyclosporine; Cytoprotection; Dose-Response Relationship, Drug; Hepatic Stellate Cells; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Male; Matrix Metalloproteinase 13; Peptidyl-Prolyl Isomerase F; Rats; Rats, Wistar; RNA Interference; RNA, Messenger; Serum Albumin; Time Factors; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta	2011
Protease profiling of liver fibrosis reveals the ADAM metallopeptidase with thrombospondin type 1 motif, 1 as a central activator of transforming growth factor beta. Hepatology (Baltimore, Md.), 2011, Volume: 54, Issue:6 Topics: ADAM Proteins; ADAMTS1 Protein; Aged; Amino Acid Motifs; Animals; Carbon Tetrachloride; Collagen Type I; Disease Models, Animal; Down-Regulation; Female; Gene Expression Profiling; Hepatic Stellate Cells; Humans; Liver Cirrhosis; Male; Mice; Middle Aged; Peptides; Protein Precursors; Transforming Growth Factor beta; Up-Regulation	2011
(Z)2-(5-(4-methoxybenzylidene)-2, 4-dioxothiazolidin-3-yl) acetic acid protects rats from CCl(4) -induced liver injury. Journal of gastroenterology and hepatology, 2012, Volume: 27, Issue:5 Topics: Alanine Transaminase; Aldehyde Reductase; Animals; Carbon Tetrachloride; Cells, Cultured; Chemical and Drug Induced Liver Injury; Enzyme Inhibitors; Glutathione; I-kappa B Proteins; Interleukin-1beta; Liver; Liver Cirrhosis, Experimental; Macrophages; Male; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Thiazolidinediones; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha	2012
Liver precursor cells increase hepatic fibrosis induced by chronic carbon tetrachloride intoxication in rats. Laboratory investigation; a journal of technical methods and pathology, 2012, Volume: 92, Issue:1 Topics: 2-Acetylaminofluorene; Actins; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Carbon Tetrachloride; Epithelial-Mesenchymal Transition; Keratin-19; Liver; Liver Cirrhosis, Experimental; Male; Rats; Rats, Sprague-Dawley; Stem Cells; Transforming Growth Factor beta	2012
A high-cholesterol diet exacerbates liver fibrosis in mice via accumulation of free cholesterol in hepatic stellate cells. Gastroenterology, 2012, Volume: 142, Issue:1 Topics: Animals; Apoptosis; Bile Ducts; Carbon Tetrachloride; Cholesterol, Dietary; Disease Models, Animal; Disease Progression; Hepatic Stellate Cells; Intracellular Signaling Peptides and Proteins; Kupffer Cells; Ligation; Liver Cirrhosis; Male; Membrane Proteins; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Niemann-Pick C1 Protein; Niemann-Pick Disease, Type C; Proteins; Signal Transduction; Time Factors; Toll-Like Receptor 4; Transforming Growth Factor beta	2012
Protease-activated receptor 2 promotes experimental liver fibrosis in mice and activates human hepatic stellate cells. Hepatology (Baltimore, Md.), 2012, Volume: 55, Issue:3 Topics: Animals; Carbon Tetrachloride; Cell Proliferation; Cells, Cultured; Collagen; Cytokines; Disease Models, Animal; Disease Progression; Hepatic Stellate Cells; Humans; Hydroxyproline; In Vitro Techniques; Liver; Liver Cirrhosis; Male; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Mice, Knockout; Oligopeptides; Receptor, PAR-2; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta	2012
Reduction of galectin-3 expression and liver fibrosis after cell therapy in a mouse model of cirrhosis. Cytotherapy, 2012, Volume: 14, Issue:3 Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Carbon Tetrachloride; Cell Movement; Chimera; Collagen Type I; Ethanol; Female; Galectin 3; Green Fluorescent Proteins; Inflammation; Liver; Liver Cirrhosis, Experimental; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Transgenic; Phagocytes; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta; Transplantation Chimera	2012
1,4-Bis[2-(3,5-dichloropyridyloxy)]benzene induces substantial hyperplasia in fibrotic mouse liver. International journal of experimental pathology, 2012, Volume: 93, Issue:2 Topics: Animals; Aryl Hydrocarbon Hydroxylases; Biomarkers; Bromodeoxyuridine; Carbon Tetrachloride; Cell Proliferation; Cyclin A; Cytochrome P450 Family 2; Disease Models, Animal; Gene Expression; Hepatocytes; Hyperplasia; Liver; Liver Cirrhosis; Liver Regeneration; Male; Mice; Mice, Inbred C57BL; Pyridines; Steroid Hydroxylases; Thioacetamide; Transforming Growth Factor beta	2012
Asiatic acid inhibits liver fibrosis by blocking TGF-beta/Smad signaling in vivo and in vitro. PloS one, 2012, Volume: 7, Issue:2 Topics: Animals; Blotting, Western; Carbon Tetrachloride; Cell Line; Collagen Type I; Gene Knockdown Techniques; Hepatic Stellate Cells; Immunohistochemistry; Liver; Liver Cirrhosis; Liver Function Tests; Male; Pentacyclic Triterpenes; Phosphorylation; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Signal Transduction; Smad Proteins; Time Factors; Transforming Growth Factor beta; Up-Regulation	2012
Sulfasalazine prevents the increase in TGF-β, COX-2, nuclear NFκB translocation and fibrosis in CCl4-induced liver cirrhosis in the rat. Human & experimental toxicology, 2012, Volume: 31, Issue:9 Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Carbon Tetrachloride; Collagen; Cyclooxygenase 2; gamma-Glutamyltransferase; Glutathione; Glutathione Disulfide; Lipid Peroxidation; Liver Cirrhosis; Liver Cirrhosis, Experimental; Male; NF-kappa B; Rats; Rats, Wistar; Sulfasalazine; Transforming Growth Factor beta	2012
Human antigen R contributes to hepatic stellate cell activation and liver fibrosis. Hepatology (Baltimore, Md.), 2012, Volume: 56, Issue:5 Topics: Actins; AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Antigens, Surface; Butadienes; Carbon Tetrachloride; Cell Movement; Cell Proliferation; Common Bile Duct; ELAV Proteins; ELAV-Like Protein 1; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Gene Silencing; Hepatic Stellate Cells; Humans; Ligation; Liver Cirrhosis; Mice; Nitriles; Phosphatidylinositol 3-Kinase; Phosphorylation; Platelet-Derived Growth Factor; Protein Serine-Threonine Kinases; Rats; RNA-Binding Proteins; RNA, Messenger; Transforming Growth Factor beta	2012
Overexpression of Smad ubiquitin regulatory factor 2 suppresses transforming growth factor-β mediated liver fibrosis. Journal of digestive diseases, 2012, Volume: 13, Issue:6 Topics: Animals; Carbon Tetrachloride; Cells, Cultured; Collagen; Disease Progression; Gene Expression Regulation; Humans; Laminin; Liver; Liver Cirrhosis; Liver Cirrhosis, Experimental; Male; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Signal Transduction; Smad7 Protein; Transfection; Transforming Growth Factor beta; Ubiquitin; Ubiquitin-Protein Ligases	2012
Protective effect of Fufang-Liu-Yue-Qing, a traditional Chinese herbal formula, on CCl4 induced liver fibrosis in rats. Journal of ethnopharmacology, 2012, Jul-13, Volume: 142, Issue:2 Topics: Actins; Animals; Antioxidants; Apoptosis; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Colchicine; Collagen; Down-Regulation; Drugs, Chinese Herbal; Interleukin-6; Lipid Peroxidation; Liver; Liver Cirrhosis, Experimental; Magnoliopsida; Male; Matrix Metalloproteinase 2; Phytotherapy; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1; Transaminases; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha	2012
The liver-specific tumor suppressor STAT5 controls expression of the reactive oxygen species-generating enzyme NOX4 and the proapoptotic proteins PUMA and BIM in mice. Hepatology (Baltimore, Md.), 2012, Volume: 56, Issue:6 Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Carbon Tetrachloride; Carcinoma, Hepatocellular; Caspase 3; Cells, Cultured; Fatty Liver; Fibroblasts; Gene Expression Regulation, Neoplastic; Growth Hormone; Hepatocytes; Liver; Liver Neoplasms; Membrane Proteins; Mice; NADPH Oxidase 4; NADPH Oxidases; Promoter Regions, Genetic; Proto-Oncogene Proteins; Reactive Oxygen Species; RNA, Messenger; Signal Transduction; STAT5 Transcription Factor; Transforming Growth Factor beta; Tumor Suppressor Proteins	2012
Hydroxysafflor yellow A attenuates carbon tetrachloride-induced hepatic fibrosis in rats by inhibiting ERK5 signaling. The American journal of Chinese medicine, 2012, Volume: 40, Issue:3 Topics: Actins; Animals; Carbon Tetrachloride; Carthamus; Chalcone; Chemical and Drug Induced Liver Injury; Collagen; Gene Expression; Hepatic Stellate Cells; Liver; Liver Cirrhosis, Experimental; Male; MEF2 Transcription Factors; Mitogen-Activated Protein Kinase 7; Myogenic Regulatory Factors; Phosphorylation; Phytotherapy; Plant Extracts; Quinones; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Transforming Growth Factor beta	2012
Deactivation of hepatic stellate cells during liver fibrosis resolution in mice. Gastroenterology, 2012, Volume: 143, Issue:4 Topics: Actins; Animals; Biomarkers; Carbon Tetrachloride; Cells, Cultured; Collagen Type I; Collagen Type I, alpha 1 Chain; Gene Expression; Genetic Techniques; Genotype; Green Fluorescent Proteins; Hepatic Stellate Cells; Integrases; Liver Cirrhosis; Male; Mice; Mice, Transgenic; Myofibroblasts; Platelet-Derived Growth Factor; Polymerase Chain Reaction; RNA, Messenger; Tamoxifen; Transforming Growth Factor beta; Vimentin	2012
Erythropoietin decreases carbon tetrachloride-induced hepatic fibrosis by inhibiting transforming growth factor-beta. Chinese medical journal, 2012, Volume: 125, Issue:17 Topics: Animals; Carbon Tetrachloride; Cells, Cultured; Erythropoietin; Fibronectins; Hepatic Stellate Cells; Liver Cirrhosis, Experimental; Male; Mice; Mice, Inbred BALB C; Recombinant Proteins; Smad2 Protein; Transforming Growth Factor beta	2012
NADPH oxidase NOX4 mediates stellate cell activation and hepatocyte cell death during liver fibrosis development. PloS one, 2012, Volume: 7, Issue:9 Topics: Animals; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Biopsy; Carbon Tetrachloride; Cell Transdifferentiation; Cyclin-Dependent Kinase Inhibitor p16; Gene Expression; Hepacivirus; Hepatic Stellate Cells; Hepatitis C, Chronic; Hepatocytes; Humans; Liver; Liver Cirrhosis; Mice; Mice, Knockout; Myofibroblasts; NADPH Oxidase 4; NADPH Oxidases; Signal Transduction; STAT3 Transcription Factor; Transforming Growth Factor beta	2012
Phenylbutyric acid protects against carbon tetrachloride-induced hepatic fibrogenesis in mice. Toxicology and applied pharmacology, 2013, Jan-15, Volume: 266, Issue:2 Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Endoplasmic Reticulum Stress; Hepatic Stellate Cells; Inflammation; Injections, Intraperitoneal; Liver Cirrhosis, Experimental; Male; Mice; Phenylbutyrates; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Unfolded Protein Response	2013
A histone deacetylase inhibitor, largazole, decreases liver fibrosis and angiogenesis by inhibiting transforming growth factor-β and vascular endothelial growth factor signalling. Liver international : official journal of the International Association for the Study of the Liver, 2013, Volume: 33, Issue:4 Topics: Acetylation; Angiogenesis Inhibitors; Animals; Apoptosis; Carbon Tetrachloride; Cell Line; Depsipeptides; Dose-Response Relationship, Drug; Hepatic Stellate Cells; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Liver; Liver Cirrhosis, Experimental; Male; Mice; Mice, Inbred BALB C; Neovascularization, Physiologic; Rats; RNA Interference; Signal Transduction; Thiazoles; Time Factors; Transfection; Transforming Growth Factor beta; Vascular Endothelial Growth Factor A	2013
Mesothelial cells give rise to hepatic stellate cells and myofibroblasts via mesothelial-mesenchymal transition in liver injury. Proceedings of the National Academy of Sciences of the United States of America, 2013, Feb-05, Volume: 110, Issue:6 Topics: Animals; Biliary Tract; Carbon Tetrachloride; Cell Lineage; Cell Transdifferentiation; Cells, Cultured; Chemical and Drug Induced Liver Injury; Epithelium; Gene Expression; Hepatic Stellate Cells; Liver; Liver Cirrhosis; Liver Regeneration; Membrane Glycoproteins; Mesoderm; Mice; Mice, Transgenic; Myofibroblasts; Nerve Tissue Proteins; RNA, Messenger; Signal Transduction; Transforming Growth Factor beta; WT1 Proteins	2013
Type XVIII collagen is essential for survival during acute liver injury in mice. Disease models & mechanisms, 2013, Volume: 6, Issue:4 Topics: Animals; Carbon Tetrachloride; Cell Death; Collagen Type XVIII; Extracellular Matrix; Gene Expression Regulation; Hepatocytes; Integrin alpha1beta1; Liver; Liver Diseases; Mice; Protein Binding; Signal Transduction; Survival Analysis; Transforming Growth Factor beta	2013
A high-fat diet and multiple administration of carbon tetrachloride induces liver injury and pathological features associated with non-alcoholic steatohepatitis in mice. Clinical and experimental pharmacology & physiology, 2013, Volume: 40, Issue:7 Topics: Alanine Transaminase; Animals; Apoptosis; Carbon Tetrachloride; Diet, High-Fat; Disease Models, Animal; DNA Copy Number Variations; DNA, Mitochondrial; Fatty Liver; Fibrosis; Glutathione; Glutathione Disulfide; Inflammation; Liver; Liver Diseases; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Obesity; Oxidative Stress; RNA, Messenger; Superoxide Dismutase; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha	2013
Recombinant bovine pancreatic trypsin inhibitor protects the liver from carbon tetrachloride-induced chronic injury in rats. Pharmaceutical biology, 2013, Volume: 51, Issue:10 Topics: Alanine Transaminase; Animals; Aprotinin; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury, Chronic; Cytoprotection; Disease Models, Animal; Fatty Liver; Hydroxyproline; Inflammation Mediators; Interleukin-1beta; Liver; Liver Cirrhosis, Experimental; Male; Necrosis; Protective Agents; Rats; Rats, Wistar; Recombinant Proteins; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Transforming Growth Factor beta	2013
Relaxin decreases the severity of established hepatic fibrosis in mice. Liver international : official journal of the International Association for the Study of the Liver, 2014, Volume: 34, Issue:3 Topics: Actins; Animals; Carbon Tetrachloride; Cells, Cultured; Collagen; Hepatic Stellate Cells; Hepatocytes; Liver; Liver Cirrhosis; Male; Matrix Metalloproteinases, Secreted; Mice; Mice, Inbred C57BL; Relaxin; Smad2 Protein; Tissue Inhibitor of Metalloproteinase-2; Transforming Growth Factor beta	2014
Systems genetics of hepatocellular damage in vivo and in vitro: identification of a critical network on chromosome 11 in mouse. Physiological genomics, 2013, Oct-16, Volume: 45, Issue:20 Topics: Animals; Carbon Tetrachloride; Chromosome Mapping; Chromosomes, Mammalian; Ethanol; Female; Gene Expression Regulation; Gene Regulatory Networks; Genetic Predisposition to Disease; Genome; Hepatocytes; L-Lactate Dehydrogenase; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Quantitative Trait Loci; Systems Biology; Transforming Growth Factor beta	2013
Human platelets inhibit liver fibrosis in severe combined immunodeficiency mice. World journal of gastroenterology, 2013, Aug-28, Volume: 19, Issue:32 Topics: Actins; Animals; Biomarkers; Carbon Tetrachloride; Caspase 3; Hepatocyte Growth Factor; Hepatocytes; Humans; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Male; Matrix Metalloproteinase 9; Mice; Mice, SCID; Phosphorylation; Platelet Transfusion; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-met; Signal Transduction; Smad3 Protein; Time Factors; Transforming Growth Factor beta	2013
Allopurinol reverses liver damage induced by chronic carbon tetrachloride treatment by decreasing oxidative stress, TGF-β production and NF-κB nuclear translocation. Pharmacology, 2013, Volume: 92, Issue:3-4 Topics: Allopurinol; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury, Chronic; Collagen; Glutathione; Glutathione Disulfide; Glycogen; Lipid Peroxidation; Liver; Male; NF-kappa B; Oxidative Stress; Rats; Rats, Wistar; Transforming Growth Factor beta; Xanthine Oxidase	2013
Impaired balance of T helper 17/T regulatory cells in carbon tetrachloride-induced liver fibrosis in mice. World journal of gastroenterology, 2014, Feb-28, Volume: 20, Issue:8 Topics: Actins; Animals; Carbon Tetrachloride; Flow Cytometry; Hepatic Stellate Cells; Interleukin-6; Liver; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; T-Lymphocytes, Regulatory; Th17 Cells; Transforming Growth Factor beta	2014
Overexpression of miR-483-5p/3p cooperate to inhibit mouse liver fibrosis by suppressing the TGF-β stimulated HSCs in transgenic mice. Journal of cellular and molecular medicine, 2014, Volume: 18, Issue:6 Topics: Animals; Carbon Tetrachloride; Carcinoma, Hepatocellular; Cells, Cultured; Coculture Techniques; Hepatic Stellate Cells; Humans; Liver Cirrhosis; Liver Neoplasms; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Mice, Transgenic; MicroRNAs; Platelet-Derived Growth Factor; Rats; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-2; Transforming Growth Factor beta	2014
SHSST cyclodextrin complex prevents the fibrosis effect on CCl₄-induced cirrhotic cardiomyopathy in rats through TGF-β pathway inhibition effects. International journal of molecular sciences, 2014, May-08, Volume: 15, Issue:5 Topics: Animals; Antioxidants; beta-Cyclodextrins; Carbon Tetrachloride; Cardiomyopathies; Drug Carriers; Drugs, Chinese Herbal; Flavanones; Heart; Liver; Liver Cirrhosis; Myocardium; Rats; Rats, Sprague-Dawley; Signal Transduction; Silymarin; Transforming Growth Factor beta	2014
Transforming growth factor-β-independent role of connective tissue growth factor in the development of liver fibrosis. The American journal of pathology, 2014, Volume: 184, Issue:10 Topics: Animals; Carbon Tetrachloride; Chronic Disease; Collagen Type I; Connective Tissue Growth Factor; Disease Models, Animal; Fibronectins; Gene Expression Regulation; Humans; Liver; Liver Cirrhosis; Mice; Mice, Knockout; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; RNA, Messenger; Signal Transduction; Transforming Growth Factor beta; Up-Regulation	2014
Hesperidin prevents liver fibrosis in rats by decreasing the expression of nuclear factor-κB, transforming growth factor-β and connective tissue growth factor. Pharmacology, 2014, Volume: 94, Issue:1-2 Topics: Animals; Antioxidants; Blotting, Western; Carbon Tetrachloride; Connective Tissue Growth Factor; Disease Models, Animal; Gene Expression Regulation; Hesperidin; Lipid Peroxidation; Liver Cirrhosis; Male; Necrosis; NF-kappa B; Oxidative Stress; Rats; Rats, Wistar; Transforming Growth Factor beta	2014
Tonsil-derived mesenchymal stem cells ameliorate CCl4-induced liver fibrosis in mice via autophagy activation. Scientific reports, 2015, Feb-27, Volume: 5 Topics: Animals; Autophagy; Carbon Tetrachloride; Cell Differentiation; Cells, Cultured; Collagen Type I; Female; Liver Cirrhosis; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice, Inbred C57BL; Palatine Tonsil; Transforming Growth Factor beta	2015
Systemic Delivery of scAAV8-Encoded MiR-29a Ameliorates Hepatic Fibrosis in Carbon Tetrachloride-Treated Mice. PloS one, 2015, Volume: 10, Issue:4 Topics: Animals; Carbon Tetrachloride; Cell Line; Chemical and Drug Induced Liver Injury; Dependovirus; Extracellular Matrix; Gene Expression Regulation; Genetic Vectors; Hepatic Stellate Cells; Hepatocytes; Humans; Liver Cirrhosis; Mice; MicroRNAs; Transforming Growth Factor beta	2015
Comparison of TGF-β, PDGF, and CTGF in hepatic fibrosis models using DMN, CCl4, and TAA. Drug and chemical toxicology, 2016, Volume: 39, Issue:1 Topics: Animals; Carbon Tetrachloride; Connective Tissue Growth Factor; Dimethylnitrosamine; Disease Models, Animal; Immunohistochemistry; Lipid Peroxidation; Liver Cirrhosis, Experimental; Male; Platelet-Derived Growth Factor; Rats; Rats, Sprague-Dawley; Thioacetamide; Transforming Growth Factor beta	2016
CD248/endosialin critically regulates hepatic stellate cell proliferation during chronic liver injury via a PDGF-regulated mechanism. Gut, 2016, Volume: 65, Issue:7 Topics: Actins; Angiogenesis Inducing Agents; Animals; Antigens, CD; Antigens, Neoplasm; Becaplermin; Carbon Tetrachloride; Cell Proliferation; Cells, Cultured; Chemical and Drug Induced Liver Injury; Chronic Disease; Collagen; Desmin; Fibrosis; Gene Expression; Hepatic Stellate Cells; Humans; Inflammation; Liver; Liver Cirrhosis; Mice; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Pathologic; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-sis; Receptor, Platelet-Derived Growth Factor alpha; Receptor, Platelet-Derived Growth Factor beta; RNA, Messenger; Signal Transduction; Transforming Growth Factor beta; Vimentin	2016
miR-30c and miR-193 are a part of the TGF-β-dependent regulatory network controlling extracellular matrix genes in liver fibrosis. Journal of digestive diseases, 2015, Volume: 16, Issue:9 Topics: Animals; Area Under Curve; Biomarkers; Carbon Tetrachloride; Cells, Cultured; Down-Regulation; Extracellular Matrix; Gene Expression; Gene Expression Profiling; Hepatic Stellate Cells; Humans; Liver Cirrhosis; Mice; MicroRNAs; Oligonucleotide Array Sequence Analysis; ROC Curve; Snail Family Transcription Factors; Transcription Factors; Transfection; Transforming Growth Factor beta	2015
SHSST-cyclodextrin complex inhibits TGF-β/Smad3/CTGF to a greater extent than silymarin in a rat model of carbon tetrachloride-induced liver injury. Molecular medicine reports, 2015, Volume: 12, Issue:4 Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Connective Tissue Growth Factor; Cyclodextrins; Dose-Response Relationship, Drug; Flavanones; Interleukin-6; Liver; Protective Agents; Rats; Rats, Sprague-Dawley; Signal Transduction; Silymarin; Smad3 Protein; Transforming Growth Factor beta	2015
Hic-5 deficiency attenuates the activation of hepatic stellate cells and liver fibrosis through upregulation of Smad7 in mice. Journal of hepatology, 2016, Volume: 64, Issue:1 Topics: Actins; Animals; Carbon Tetrachloride; Cells, Cultured; Cytoskeletal Proteins; DNA-Binding Proteins; Hepatic Stellate Cells; Humans; LIM Domain Proteins; Liver Cirrhosis; Mice; Mice, Inbred C57BL; Smad2 Protein; Smad7 Protein; Transforming Growth Factor beta; Up-Regulation	2016
Molecular Mechanism Responsible for Fibronectin-controlled Alterations in Matrix Stiffness in Advanced Chronic Liver Fibrogenesis. The Journal of biological chemistry, 2016, Jan-01, Volume: 291, Issue:1 Topics: Animals; Biological Availability; Carbon Tetrachloride; Chronic Disease; Collagen; Extracellular Matrix; Fibronectins; Hepatic Stellate Cells; Liver; Liver Cirrhosis; Mice; Mutation; Myofibroblasts; Protein-Lysine 6-Oxidase; Transforming Growth Factor beta	2016
Doxazosin Treatment Attenuates Carbon Tetrachloride-Induced Liver Fibrosis in Hamsters through a Decrease in Transforming Growth Factor β Secretion. Gut and liver, 2016, Volume: 10, Issue:1 Topics: Adrenergic alpha-1 Receptor Antagonists; Alanine Transaminase; Animals; Aspartate Aminotransferases; Bilirubin; Carbazoles; Carbon Tetrachloride; Carvedilol; Collagen Type I; Cricetinae; Doxazosin; Liver; Liver Cirrhosis; Liver Function Tests; Propanolamines; Serum Albumin; Transforming Growth Factor beta	2016
Glycoprotein Nonmetastatic Melanoma B (Gpnmb)-Positive Macrophages Contribute to the Balance between Fibrosis and Fibrolysis during the Repair of Acute Liver Injury in Mice. PloS one, 2015, Volume: 10, Issue:11 Topics: Acute Disease; Alanine Transaminase; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Collagen; Eye Proteins; Liver; Liver Cirrhosis; Macrophages; Matrix Metalloproteinase 13; Matrix Metalloproteinase 9; Membrane Glycoproteins; Mice, Inbred C57BL; Mice, Inbred DBA; Phagocytosis; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta; Wound Healing	2015
New role and molecular mechanism of Gadd45a in hepatic ﬁbrosis. World journal of gastroenterology, 2016, Mar-07, Volume: 22, Issue:9 Topics: Actins; Animals; Carbon Tetrachloride; Cell Cycle Proteins; Cells, Cultured; Collagen Type I; Hepatic Stellate Cells; Liver; Liver Cirrhosis, Experimental; Male; Mice, Inbred BALB C; Nuclear Proteins; Phosphorylation; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; Signal Transduction; Smad3 Protein; Time Factors; Transfection; Transforming Growth Factor beta	2016
Trillin Reduces Liver Chronic Inflammation and Fibrosis in Carbon Tetrachloride (CCl4) Induced Liver Injury in Mice. Immunological investigations, 2016, Volume: 45, Issue:5 Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; Carbon Tetrachloride; Dioscorea; Enzyme-Linked Immunosorbent Assay; Hepatitis; Humans; Injections, Intraperitoneal; Interleukin-1beta; Interleukin-6; Liver Cirrhosis; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; NF-kappa B; Saponins; Superoxide Dismutase; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha	2016
The common dietary flavonoid myricetin attenuates liver fibrosis in carbon tetrachloride treated mice. Molecular nutrition & food research, 2017, Volume: 61, Issue:4 Topics: Animals; Antifibrinolytic Agents; Becaplermin; Carbon Tetrachloride; Cell Movement; Collagen Type I; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Hepatic Stellate Cells; Liver Cirrhosis; Mice; Phosphorylation; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-sis; Signal Transduction; Transforming Growth Factor beta; Transforming Growth Factor beta1	2017
Positive feedback loop of YB-1 interacting with Smad2 promotes liver fibrosis. Biochemical and biophysical research communications, 2017, 03-18, Volume: 484, Issue:4 Topics: Animals; Carbon Tetrachloride; Cell Line; Feedback, Physiological; HEK293 Cells; Humans; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Signal Transduction; Smad2 Protein; Transcription Factors; Transforming Growth Factor beta; Ubiquitination	2017
Tyrosine kinase inhibitor BIBF1120 ameliorates inflammation, angiogenesis and fibrosis in CCl Scientific reports, 2017, 03-14, Volume: 7 Topics: 3T3 Cells; Animals; Carbon Tetrachloride; Disease Models, Animal; Humans; Indoles; Inflammation; Liver Cirrhosis; Mice; Neovascularization, Pathologic; Protein-Tyrosine Kinases; Signal Transduction; Transforming Growth Factor beta	2017
Ductular reaction correlates with fibrogenesis but does not contribute to liver regeneration in experimental fibrosis models. PloS one, 2017, Volume: 12, Issue:4 Topics: Animals; Carbon Tetrachloride; Cell Proliferation; Disease Models, Animal; Erlotinib Hydrochloride; Fibrosis; Imatinib Mesylate; Keratin-19; Liver; Liver Cirrhosis; Liver Regeneration; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Confocal; Protein Kinase Inhibitors; Thioacetamide; Transforming Growth Factor beta	2017
Bone marrow endothelial progenitor cells activate hepatic stellate cells and aggravate carbon tetrachloride induced liver fibrosis in mice via paracrine factors. Cell proliferation, 2017, Volume: 50, Issue:4 Topics: Animals; Bone Marrow Cells; Carbon Tetrachloride; Cells, Cultured; Coculture Techniques; Culture Media, Conditioned; Disease Models, Animal; Endothelial Cells; Hepatic Stellate Cells; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Paracrine Communication; Transforming Growth Factor beta; Vascular Endothelial Growth Factor A	2017
Schisandrin B attenuates CCl Drug design, development and therapy, 2017, Volume: 11 Topics: Animals; Carbon Tetrachloride; Cyclooctanes; Lignans; Liver Cirrhosis; Male; Molecular Structure; NF-E2-Related Factor 2; Polycyclic Compounds; Rats; Rats, Wistar; Signal Transduction; Smad Proteins; Transforming Growth Factor beta	2017
Dynamic regulation of canonical TGFβ signalling by endothelial transcription factor ERG protects from liver fibrogenesis. Nature communications, 2017, 10-12, Volume: 8, Issue:1 Topics: Animals; Carbon Tetrachloride; Cells, Cultured; Down-Regulation; End Stage Liver Disease; Endothelial Cells; Epithelial-Mesenchymal Transition; Etanercept; Female; Fibrosis; Human Umbilical Vein Endothelial Cells; Humans; Liver; Liver Cirrhosis, Biliary; Liver Cirrhosis, Experimental; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oncogene Proteins; Signal Transduction; Smad1 Protein; Smad2 Protein; Smad3 Protein; Transcriptional Regulator ERG; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Up-Regulation	2017
Lipopolysaccharide mediates hepatic stellate cell activation by regulating autophagy and retinoic acid signaling. Autophagy, 2017, Volume: 13, Issue:11 Topics: Actins; Animals; Autophagy; Bacterial Translocation; Carbon Tetrachloride; Cells, Cultured; Collagen Type I; Collagen Type I, alpha 1 Chain; Down-Regulation; Gram-Negative Bacteria; Hepatic Stellate Cells; Lipid Droplets; Lipopolysaccharides; Liver Cirrhosis, Experimental; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Receptors, Retinoic Acid; Signal Transduction; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta; Tretinoin	2017
Antifibrotic effects of D-limonene (5(1-methyl-4-[1-methylethenyl]) cyclohexane) in CCl Environmental toxicology, 2018, Volume: 33, Issue:3 Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Carbon Tetrachloride; Cyclohexenes; Glutathione; Limonene; Liver; Liver Cirrhosis; Male; NF-kappa B; Oxidative Stress; Rats, Wistar; Terpenes; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha	2018
MicroRNA-212 activates hepatic stellate cells and promotes liver fibrosis via targeting SMAD7. Biochemical and biophysical research communications, 2018, 01-29, Volume: 496, Issue:1 Topics: Animals; Carbon Tetrachloride; Cells, Cultured; Hepatic Stellate Cells; Liver; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Protein Binding; Smad7 Protein; Transforming Growth Factor beta	2018
Renin-angiotensin system inhibition ameliorates CCl Canadian journal of physiology and pharmacology, 2018, Volume: 96, Issue:6 Topics: Actins; Alanine Transaminase; alpha-Fetoproteins; Animals; Carbon Tetrachloride; Gene Expression Regulation; Hydroxyproline; Liver Cirrhosis; Male; Matrix Metalloproteinase 2; Mice; NF-kappa B; Renin-Angiotensin System; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha	2018
Systemic inhibition of BMP1-3 decreases progression of CCl Growth factors (Chur, Switzerland), 2017, Volume: 35, Issue:6 Topics: Actins; Animals; Antibodies; Bone Morphogenetic Proteins; Carbon Tetrachloride; Cell Line; Collagen Type I; Decorin; Humans; Liver Cirrhosis; Male; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta	2017
H19/miR-148a/USP4 axis facilitates liver fibrosis by enhancing TGF-β signaling in both hepatic stellate cells and hepatocytes. Journal of cellular physiology, 2019, Volume: 234, Issue:6 Topics: Animals; Base Sequence; Carbon Tetrachloride; Cell Line; Epithelial-Mesenchymal Transition; Hepatic Stellate Cells; Hepatocytes; Humans; Liver Cirrhosis; Male; Mice, Inbred C57BL; MicroRNAs; Receptor, Transforming Growth Factor-beta Type I; RNA, Long Noncoding; Signal Transduction; Transforming Growth Factor beta; Ubiquitin-Specific Proteases; Up-Regulation	2019
CDH11 promotes liver fibrosis via activation of hepatic stellate cells. Biochemical and biophysical research communications, 2019, 01-08, Volume: 508, Issue:2 Topics: Animals; Cadherins; Carbon Tetrachloride; Cells, Cultured; Hepatic Stellate Cells; Humans; Liver Cirrhosis; Mice; Prognosis; Transforming Growth Factor beta	2019
α‑lipoic acid protects against carbon tetrachloride‑induced liver cirrhosis through the suppression of the TGF‑β/Smad3 pathway and autophagy. Molecular medicine reports, 2019, Volume: 19, Issue:2 Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Autophagy; Carbon Tetrachloride; Down-Regulation; Liver; Liver Cirrhosis; Male; Protective Agents; Rats; Rats, Sprague-Dawley; Signal Transduction; Smad3 Protein; Thioctic Acid; Transforming Growth Factor beta; Up-Regulation	2019
Enhancer of Zeste Homologue 2 Inhibition Attenuates TGF-β Dependent Hepatic Stellate Cell Activation and Liver Fibrosis. Cellular and molecular gastroenterology and hepatology, 2019, Volume: 7, Issue:1 Topics: Animals; Bile Ducts; Carbon Tetrachloride; Enhancer of Zeste Homolog 2 Protein; Extracellular Matrix Proteins; Hepatic Stellate Cells; Humans; Ligation; Liver Cirrhosis; Mice, Inbred C57BL; Platelet-Derived Growth Factor; Transforming Growth Factor beta; Up-Regulation	2019
Carvacrol ameliorates the progression of liver fibrosis through targeting of Hippo and TGF-β signaling pathways in carbon tetrachloride (CCl Immunopharmacology and immunotoxicology, 2019, Volume: 41, Issue:1 Topics: Acyltransferases; Animals; Anti-Inflammatory Agents; Apoptosis Regulatory Proteins; Carbon Tetrachloride; Cymenes; Disease Progression; Liver; Liver Cirrhosis, Experimental; Male; Monoterpenes; Rats, Wistar; Signal Transduction; Transcription Factors; Transforming Growth Factor beta; YAP-Signaling Proteins	2019
Locostatin Alleviates Liver Fibrosis Induced by Carbon Tetrachloride in Mice. Digestive diseases and sciences, 2019, Volume: 64, Issue:9 Topics: Actins; Animals; Carbon Tetrachloride; Cell Movement; Collagen Type I; Collagen Type II; E-Selectin; Hepatic Stellate Cells; Hydroxyproline; Liver Cirrhosis; Male; Matrix Metalloproteinase 13; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Oxazolidinones; Peroxidase; Phosphatidylethanolamine Binding Protein; Platelet-Derived Growth Factor; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Transforming Growth Factor beta	2019
Inhibitory Effect of Sestrin 2 on Hepatic Stellate Cell Activation and Liver Fibrosis. Antioxidants & redox signaling, 2019, 07-20, Volume: 31, Issue:3 Topics: Animals; Binding Sites; Carbon Tetrachloride; Cells, Cultured; Disease Models, Animal; Down-Regulation; Hepatic Stellate Cells; Humans; Liver Cirrhosis; Male; Mice; Nuclear Proteins; Promoter Regions, Genetic; Smad3 Protein; Transforming Growth Factor beta	2019
Nicotinamide riboside protects against liver fibrosis induced by CCl Life sciences, 2019, May-15, Volume: 225 Topics: Acetylation; Animals; Carbon Tetrachloride; E1A-Associated p300 Protein; Gene Expression Regulation; Hepatic Stellate Cells; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Niacinamide; Protective Agents; Pyridinium Compounds; Sirtuin 1; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta	2019
TG101348, a selective JAK2 antagonist, ameliorates hepatic fibrogenesis FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019, Volume: 33, Issue:8 Topics: 3T3 Cells; Animals; Carbon Tetrachloride; Cell Line, Tumor; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Hep G2 Cells; Humans; Liver; Liver Cirrhosis; Macrophages; Male; Mice; Mice, Inbred C57BL; Myofibroblasts; Nitrogen Oxides; Pyrrolidines; Signal Transduction; Sulfonamides; Transforming Growth Factor beta	2019
Cadherin-11 contributes to liver fibrosis induced by carbon tetrachloride. PloS one, 2019, Volume: 14, Issue:7 Topics: Animals; Cadherins; Carbon Tetrachloride; Cells, Cultured; Collagen; Extracellular Matrix; Hepatic Stellate Cells; Hepatocytes; Humans; Liver; Liver Cirrhosis; Mice; Mice, Knockout; Transforming Growth Factor beta	2019
Calpain 9 as a therapeutic target in TGFβ-induced mesenchymal transition and fibrosis. Science translational medicine, 2019, 07-17, Volume: 11, Issue:501 Topics: Angiotensin II; Animals; Bleomycin; Calcium-Binding Proteins; Calpain; Carbon Tetrachloride; Cell Line; Dogs; Epithelial-Mesenchymal Transition; Fibrosis; Humans; Isoenzymes; Liver Cirrhosis; Male; Mice, Inbred C57BL; Molecular Targeted Therapy; Myocardium; Protein Biosynthesis; Protein Multimerization; RNA Stability; Signal Transduction; Transforming Growth Factor beta	2019
The Therapeutic Mechanisms of Propolis Against CCl Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2019, Volume: 53, Issue:2 Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Carbon Tetrachloride; Cytokines; Hepatic Stellate Cells; Liver; Liver Cirrhosis, Experimental; Male; Mice; Mice, Inbred BALB C; Nitric Oxide Synthase Type II; Phosphatidylinositol 3-Kinases; Propolis; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Signal Transduction; Smad2 Protein; TOR Serine-Threonine Kinases; Transforming Growth Factor beta; Tumor Suppressor Protein p53	2019
ECM1 Prevents Activation of Transforming Growth Factor β, Hepatic Stellate Cells, and Fibrogenesis in Mice. Gastroenterology, 2019, Volume: 157, Issue:5 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Extracellular Matrix Proteins; Hepatic Stellate Cells; Hepatitis, Alcoholic; Hepatitis, Viral, Human; Humans; Liver; Liver Cirrhosis, Alcoholic; Liver Cirrhosis, Experimental; Male; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Signal Transduction; Transforming Growth Factor beta	2019
Praziquantel ameliorates CCl British journal of pharmacology, 2019, Volume: 176, Issue:24 Topics: Animals; Carbon Tetrachloride; Cell Line; Disease Models, Animal; Gene Expression; Hepatic Stellate Cells; Humans; Liver Cirrhosis; Mice; NIH 3T3 Cells; Praziquantel; Signal Transduction; Smad Proteins; Smad7 Protein; Transforming Growth Factor beta; Up-Regulation	2019
Antler stem cells as a novel stem cell source for reducing liver fibrosis. Cell and tissue research, 2020, Volume: 379, Issue:1 Topics: Actins; Animals; Antlers; Carbon Tetrachloride; Cell Proliferation; Coculture Techniques; Collagen; Deer; Disease Models, Animal; Hepatic Stellate Cells; Liver; Liver Cirrhosis; Male; Mesenchymal Stem Cell Transplantation; Proliferating Cell Nuclear Antigen; Rats; Stem Cell Transplantation; Stem Cells; Transforming Growth Factor beta	2020
Antifibrotic effects of hypocalcemic vitamin D analogs in murine and human hepatic stellate cells and in the CCl Laboratory investigation; a journal of technical methods and pathology, 2019, Volume: 99, Issue:12 Topics: Animals; Calcitriol; Calcium; Carbon Tetrachloride; Cell Line; Drug Evaluation, Preclinical; Ergocalciferols; Hepatic Stellate Cells; Humans; Kupffer Cells; Liver Cirrhosis; Male; Mice, Inbred C57BL; Primary Cell Culture; Transforming Growth Factor beta; Vitamin D	2019
Effects of Bone Marrow-Derived Mesenchymal Stem Cells on Hypoxia and the Transforming Growth Factor beta 1 (TGFβ-1) and SMADs Pathway in a Mouse Model of Cirrhosis. Medical science monitor : international medical journal of experimental and clinical research, 2019, Sep-24, Volume: 25 Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bone Marrow; Carbon Tetrachloride; Cell Hypoxia; China; Disease Models, Animal; Fibrosis; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Liver; Liver Cirrhosis; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Smad Proteins; Transforming Growth Factor beta	2019
TAF and TDF attenuate liver fibrosis through NS5ATP9, TGFβ1/Smad3, and NF-κB/NLRP3 inflammasome signaling pathways. Hepatology international, 2020, Volume: 14, Issue:1 Topics: Adenine; Alanine; Animals; Antiviral Agents; Carbon Tetrachloride; Disease Models, Animal; DNA-Binding Proteins; Liver Cirrhosis, Experimental; Male; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Smad3 Protein; Tenofovir; Transforming Growth Factor beta	2020
Hepatoprotective effect of a fucoidan extract from Sargassum fluitans Borgesen against CCl International journal of biological macromolecules, 2020, Feb-15, Volume: 145 Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Disease Models, Animal; Gene Expression Regulation; Humans; Liver; Liver Cirrhosis; Plant Extracts; Polysaccharides; Rats; Sargassum; Signal Transduction; Smad Proteins; Smad3 Protein; Transforming Growth Factor beta; Transforming Growth Factor beta1	2020
AT-MSCs Antifibrotic Activity is Improved by Eugenol through Modulation of TGF-β/Smad Signaling Pathway in Rats. Molecules (Basel, Switzerland), 2020, Jan-15, Volume: 25, Issue:2 Topics: Animals; Anti-Infective Agents; Carbon Tetrachloride; Eugenol; Liver Cirrhosis; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Rats; Rats, Sprague-Dawley; Signal Transduction; Smad Proteins; Transforming Growth Factor beta	2020
Deletion of Protein Kinase D3 Promotes Liver Fibrosis in Mice. Hepatology (Baltimore, Md.), 2020, Volume: 72, Issue:5 Topics: Animals; Carbon Tetrachloride; Cells, Cultured; Disease Progression; Hepatic Stellate Cells; Humans; Liver; Liver Cirrhosis; Liver Cirrhosis, Experimental; Macrophages; Mice; Mice, Knockout; Myofibroblasts; Primary Cell Culture; Protein Kinase C; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Severity of Illness Index; Tissue Array Analysis; Transforming Growth Factor beta	2020
TGF-β/Smad and JAK/STAT pathways are involved in the anti-fibrotic effects of propylene glycol alginate sodium sulphate on hepatic fibrosis. Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:9 Topics: Alginates; Animals; Autophagy; Bile Ducts; Carbon Tetrachloride; Disease Models, Animal; Down-Regulation; Hepatic Stellate Cells; Janus Kinases; Ligation; Liver Cirrhosis; Male; Matrix Metalloproteinase 2; Mice, Inbred C57BL; Models, Biological; Signal Transduction; Smad Proteins; STAT Transcription Factors; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta; Up-Regulation	2020
Comparative study on effect of mesenchymal stem cells and endothelial progenitor cells on treatment of experimental CCL4-induced liver fibrosis. Archives of physiology and biochemistry, 2022, Volume: 128, Issue:4 Topics: Albumins; Animals; Carbon Tetrachloride; Endothelial Progenitor Cells; Liver Cirrhosis; Matrix Metalloproteinase 2; Mesenchymal Stem Cells; Rats; Transforming Growth Factor beta; Vascular Endothelial Growth Factor A	2022
Pelargonidin ameliorates CCl Food & function, 2020, Jun-24, Volume: 11, Issue:6 Topics: Actins; Animals; Anthocyanins; Carbon Tetrachloride; Cell Line; Collagen; Hepatic Stellate Cells; Humans; Inflammasomes; Interleukin-1beta; Liver; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Reactive Oxygen Species; Signal Transduction; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta	2020
Byakangelicin protects against carbon tetrachloride-induced liver injury and fibrosis in mice. Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:15 Topics: Animals; Apoptosis; Biopsy; Carbon Tetrachloride; Cells, Cultured; Chemical and Drug Induced Liver Injury; Cytokines; Disease Models, Animal; Furocoumarins; Hepatic Stellate Cells; Hepatocytes; Liver Cirrhosis; Male; Mice; Protective Agents; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta	2020
Physalin D attenuates hepatic stellate cell activation and liver fibrosis by blocking TGF-β/Smad and YAP signaling. Phytomedicine : international journal of phytotherapy and phytopharmacology, 2020, Volume: 78 Topics: Actins; Adaptor Proteins, Signal Transducing; Animals; Carbon Tetrachloride; Cells, Cultured; Collagen Type I; Collagen Type I, alpha 1 Chain; Hepatic Stellate Cells; Humans; Liver Cirrhosis; Male; Mice, Inbred C57BL; Secosteroids; Signal Transduction; Smad Proteins; Transcription Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1; YAP-Signaling Proteins	2020
SB431542-Loaded Liposomes Alleviate Liver Fibrosis by Suppressing TGF-β Signaling. Molecular pharmaceutics, 2020, 11-02, Volume: 17, Issue:11 Topics: Animals; Benzamides; Carbon Tetrachloride; Cell Line; Dioxoles; Disease Models, Animal; Drug Liberation; Hepatic Stellate Cells; Humans; Liposomes; Liver Cirrhosis, Experimental; Male; Mice; Mice, Inbred C57BL; Rats; Rats, Sprague-Dawley; Signal Transduction; Tissue Distribution; Transforming Growth Factor beta	2020
Transcriptional factor ATF3 promotes liver fibrosis via activating hepatic stellate cells. Cell death & disease, 2020, 12-14, Volume: 11, Issue:12 Topics: Activating Transcription Factor 3; Animals; Carbon Tetrachloride; Cells, Cultured; Feedback, Physiological; Gene Expression Regulation; Hepatic Stellate Cells; Humans; Liver Cirrhosis; Mice; RNA, Long Noncoding; Smad3 Protein; Transforming Growth Factor beta; Up-Regulation	2020
Transforming Growth Factor Beta-Induced Foxo3a Acts as a Profibrotic Mediator in Hepatic Stellate Cells. Toxicological sciences : an official journal of the Society of Toxicology, 2021, 01-28, Volume: 179, Issue:2 Topics: Animals; Carbon Tetrachloride; Hepatic Stellate Cells; Humans; Liver Cirrhosis; Mice; Transforming Growth Factor beta	2021
The Effect of Lecithins Coupled Decorin Nanoliposomes on Treatment of Carbon Tetrachloride-Induced Liver Fibrosis. BioMed research international, 2020, Volume: 2020 Topics: Animals; Bile Ducts; Carbon Tetrachloride; Cell Line; Cell Proliferation; Decorin; Lecithins; Liposomes; Liver Cirrhosis; Male; Nanoparticles; Rats, Sprague-Dawley; Transforming Growth Factor beta	2020
Tectona grandis leaf extract ameliorates hepatic fibrosis: Modulation of TGF- β /Smad signaling pathway and upregulating MMP3/TIMP1 ratio. Journal of ethnopharmacology, 2021, May-23, Volume: 272 Topics: Animals; Carbon Tetrachloride; Cell Survival; Chlorocebus aethiops; Collagen; Disease Models, Animal; Dose-Response Relationship, Drug; Hep G2 Cells; Hepatic Stellate Cells; Humans; Lamiaceae; Liver Cirrhosis; Matrix Metalloproteinase 3; Mice, Inbred C57BL; Plant Extracts; Plant Leaves; Protective Agents; Signal Transduction; Smad2 Protein; Tissue Inhibitor of Metalloproteinase-1; Transaminases; Transforming Growth Factor beta; Vero Cells	2021
Neoagarooligosaccharide Protects against Hepatic Fibrosis via Inhibition of TGF-β/Smad Signaling Pathway. International journal of molecular sciences, 2021, Feb-18, Volume: 22, Issue:4 Topics: Animals; Carbon Tetrachloride; Cell Line; Gene Expression Regulation; Hepatic Stellate Cells; Humans; Liver Cirrhosis; Male; Mice, Inbred ICR; Oligosaccharides; Protective Agents; Signal Transduction; Smad Proteins; Transforming Growth Factor beta	2021
Ligustroflavone ameliorates CCl Chinese journal of natural medicines, 2021, Volume: 19, Issue:3 Topics: Animals; Apigenin; Carbon Tetrachloride; Glycosides; Hepatic Stellate Cells; Liver; Liver Cirrhosis; Mice; Signal Transduction; Smad Proteins; Transforming Growth Factor beta	2021
Ketogenic Diet Enhances the Cholesterol Accumulation in Liver and Augments the Severity of CCl International journal of molecular sciences, 2021, Mar-13, Volume: 22, Issue:6 Topics: 3-Hydroxybutyric Acid; Acetoacetates; Actins; Animals; Becaplermin; Carbon Tetrachloride; Catalase; Cell Proliferation; Cholesterol; Collagen Type I; Cytochrome P-450 CYP1A2; Desmin; Diet, Ketogenic; Disease Progression; Gene Expression Regulation; Hepatic Stellate Cells; Liver; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Primary Cell Culture; Severity of Illness Index; Superoxide Dismutase; Superoxide Dismutase-1; Thioacetamide; Transforming Growth Factor beta	2021
CD39-mediated ATP-adenosine signalling promotes hepatic stellate cell activation and alcoholic liver disease. European journal of pharmacology, 2021, Aug-15, Volume: 905 Topics: 5'-Nucleotidase; Acetaldehyde; Adenosine; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Carbon Tetrachloride; Colchicine; Cytokines; Disease Models, Animal; Ethanol; Gene Knockdown Techniques; Hepatic Stellate Cells; Humans; Liver Diseases, Alcoholic; Mice, Inbred C57BL; Primary Cell Culture; Rats; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta; Tungsten Compounds	2021
Cyclam-Modified Polyethyleneimine for Simultaneous TGFβ siRNA Delivery and CXCR4 Inhibition for the Treatment of CCl International journal of nanomedicine, 2021, Volume: 16 Topics: Animals; Apoptosis; Carbon Tetrachloride; Drug Carriers; Gene Silencing; Heterocyclic Compounds; Humans; Liver Cirrhosis; Mice; Particle Size; Polyethyleneimine; Receptors, CXCR4; RNA, Small Interfering; Transforming Growth Factor beta	2021
Effect of Curcumol on NOD-Like Receptor Thermoprotein Domain 3 Inflammasomes in Liver Fibrosis of Mice. Chinese journal of integrative medicine, 2022, Volume: 28, Issue:11 Topics: Animals; Carbon Tetrachloride; Caspase 1; Collagen; Eosine Yellowish-(YS); Hematoxylin; Inflammasomes; Interleukin-1beta; Liver Cirrhosis; Mice; NLR Family, Pyrin Domain-Containing 3 Protein; NLR Proteins; Peanut Oil; RNA, Messenger; Saline Solution; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha	2022
Rebalancing TGF-β/Smad7 signaling via Compound kushen injection in hepatic stellate cells protects against liver fibrosis and hepatocarcinogenesis. Clinical and translational medicine, 2021, Volume: 11, Issue:7 Topics: Animals; Carbon Tetrachloride; Carcinoma, Hepatocellular; Cell Line; Drugs, Chinese Herbal; Hepatic Stellate Cells; Humans; Liver; Liver Cirrhosis; Liver Neoplasms; Male; Medicine, Chinese Traditional; Meta-Analysis as Topic; Mice; Mice, Inbred C57BL; RNA Interference; RNA, Small Interfering; Signal Transduction; Smad7 Protein; Transforming Growth Factor beta	2021
C1q/tumor necrosis factor-related protein-3 acts as a target treating hepatic fibrosis. European review for medical and pharmacological sciences, 2021, Volume: 25, Issue:17 Topics: Adipokines; Animals; Carbon Tetrachloride; Disease Models, Animal; Extracellular Matrix; Gene Knockout Techniques; Hepatic Stellate Cells; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Transforming Growth Factor beta	2021
Saikosaponin-d alleviates hepatic fibrosis through regulating GPER1/autophagy signaling. Molecular biology reports, 2021, Volume: 48, Issue:12 Topics: Animals; Autophagy; Carbon Tetrachloride; Cells, Cultured; China; Fibrosis; Hepatic Stellate Cells; Humans; Liver; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Oleanolic Acid; Receptors, Estrogen; Receptors, G-Protein-Coupled; Saponins; Signal Transduction; Transforming Growth Factor beta	2021
Amygdalin Ameliorates Liver Fibrosis through Inhibiting Activation of TGF-β/Smad Signaling. Chinese journal of integrative medicine, 2023, Volume: 29, Issue:4 Topics: Amygdalin; Animals; Carbon Tetrachloride; Collagen Type I; Endothelial Cells; Hepatic Stellate Cells; Liver; Liver Cirrhosis; Male; Mice; Olive Oil; Rats; Rats, Wistar; Signal Transduction; Smad Proteins; Transforming Growth Factor beta; Transforming Growth Factor beta1	2023
Fibroblast growth factor 18 attenuates liver fibrosis and HSCs activation via the SMO-LATS1-YAP pathway. Pharmacological research, 2022, Volume: 178 Topics: Animals; Carbon Tetrachloride; Fibroblast Growth Factors; Hepatic Stellate Cells; Liver; Liver Cirrhosis; Mice; Protein Serine-Threonine Kinases; Transforming Growth Factor beta; Transforming Growth Factor beta1	2022
The combination of experimental periodontitis and oral microbiota from periodontitis patients aggravates liver fibrosis in mice. Journal of clinical periodontology, 2022, Volume: 49, Issue:10 Topics: Actins; Alanine Transaminase; Animals; Azo Compounds; Carbon Tetrachloride; Hydroxyproline; Liver Cirrhosis; Male; Methylene Blue; Mice; Microbiota; Periodontitis; RNA, Ribosomal, 16S; Transforming Growth Factor beta	2022
Activin B promotes the initiation and progression of liver fibrosis. Hepatology communications, 2022, Volume: 6, Issue:10 Topics: Activins; Adenosine Diphosphate; Animals; Carbon Tetrachloride; Humans; Liver Cirrhosis; Mice; Nitric Oxide Synthase Type II; Ribose; Transforming Growth Factor beta	2022
miR-345-5p curbs hepatic stellate cell activation and liver fibrosis progression by suppressing hypoxia-inducible factor-1alpha expression. Toxicology letters, 2022, Nov-01, Volume: 370 Topics: 3' Untranslated Regions; Animals; Carbon Tetrachloride; Cell Proliferation; Fibrosis; Hepatic Stellate Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Liver Cirrhosis; Mice; MicroRNAs; RNA, Messenger; Transforming Growth Factor beta	2022
Combination Treatment with Hydroxytyrosol and Vitamin E Improves NAFLD-Related Fibrosis. Nutrients, 2022, Sep-14, Volume: 14, Issue:18 Topics: Animals; Carbon Tetrachloride; Fibrosis; Liver; Liver Cirrhosis; Mice; Non-alcoholic Fatty Liver Disease; Phenylethyl Alcohol; Reactive Oxygen Species; Transcription Factors; Transforming Growth Factor beta; Vitamin E	2022
ADSCs-derived exosomes ameliorate hepatic fibrosis by suppressing stellate cell activation and remodeling hepatocellular glutamine synthetase-mediated glutamine and ammonia homeostasis. Stem cell research & therapy, 2022, 10-04, Volume: 13, Issue:1 Topics: Ammonia; Animals; Carbon Tetrachloride; Carcinoma, Hepatocellular; Diethylnitrosamine; Exosomes; Fibrosis; Glutamate-Ammonia Ligase; Glutamine; Hepatic Stellate Cells; Homeostasis; Liver Cirrhosis; Liver Neoplasms; Mice; Stromal Cells; Transforming Growth Factor beta	2022
Enhanced Expression of ARK5 in Hepatic Stellate Cell and Hepatocyte Synergistically Promote Liver Fibrosis. International journal of molecular sciences, 2022, Oct-28, Volume: 23, Issue:21 Topics: Animals; Carbon Tetrachloride; Hepatic Stellate Cells; Hepatocytes; Liver; Liver Cirrhosis; Mice; Receptor, Transforming Growth Factor-beta Type I; Transforming Growth Factor beta	2022
[Therapeutic effect of Jingfang Granules on CCl_4-induced liver fibrosis in mice and its mechanism]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2022, Volume: 47, Issue:22 Topics: Animals; Carbon Tetrachloride; Interleukin-6; Liver; Liver Cirrhosis; Male; Mice; Olive Oil; Superoxide Dismutase; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha	2022
[Effect of forsythiaside A against CCl_4-induced liver fibrosis in mice and its mechanism]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2022, Volume: 47, Issue:22 Topics: Actins; Alanine Transaminase; Animals; Carbon Tetrachloride; Collagen; Glycosides; Hepatic Stellate Cells; Liver; Liver Cirrhosis; Mice; RNA, Messenger; Transforming Growth Factor beta	2022
Kinin B1 receptor blockade attenuates hepatic fibrosis and portal hypertension in chronic liver diseases in mice. Journal of translational medicine, 2022, 12-13, Volume: 20, Issue:1 Topics: Animals; Carbon Tetrachloride; Fibrosis; Hepatic Stellate Cells; Humans; Hypertension, Portal; Kinins; Liver; Liver Cirrhosis; Mice; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Receptors, Peptide; Transforming Growth Factor beta	2022
Miglustat, a glucosylceramide synthase inhibitor, mitigates liver fibrosis through TGF-β/Smad pathway suppression in hepatic stellate cells. Biochemical and biophysical research communications, 2023, 01-29, Volume: 642 Topics: Animals; Carbon Tetrachloride; Hepatic Stellate Cells; Humans; Liver; Liver Cirrhosis; Mice; Mice, Inbred C57BL; Signal Transduction; Smad Proteins; Transforming Growth Factor beta; Transforming Growth Factor beta1	2023
Tyrosine kinase receptor B attenuates liver fibrosis by inhibiting TGF-β/SMAD signaling. Hepatology (Baltimore, Md.), 2023, 11-01, Volume: 78, Issue:5 Topics: Animals; Carbon Tetrachloride; Hepatic Stellate Cells; Liver; Liver Cirrhosis; Mice; Non-alcoholic Fatty Liver Disease; Receptor Protein-Tyrosine Kinases; Signal Transduction; Smad Proteins; Transforming Growth Factor beta; Transforming Growth Factor beta1; Ubiquitin-Protein Ligases	2023
HOXC8/TGF-β1 positive feedback loop promotes liver fibrosis and hepatic stellate cell activation via activating Smad2/Smad3 signaling. Biochemical and biophysical research communications, 2023, 06-25, Volume: 662 Topics: Animals; Carbon Tetrachloride; Feedback; Fibrosis; Hepatic Stellate Cells; Homeodomain Proteins; Humans; Liver; Liver Cirrhosis; Mice; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta; Transforming Growth Factor beta1	2023
MFAP2 promotes HSCs activation through FBN1/TGF-β/Smad3 pathway. Journal of cellular and molecular medicine, 2023, Volume: 27, Issue:21 Topics: Animals; Carbon Tetrachloride; Fibrillin-1; Hepatic Stellate Cells; Liver; Liver Cirrhosis; Mice; Microfibrils; Transforming Growth Factor beta; Transforming Growth Factor beta1	2023
Hydronidone ameliorates liver fibrosis by inhibiting activation of hepatic stellate cells via Smad7-mediated degradation of TGFβRI. Liver international : official journal of the International Association for the Study of the Liver, 2023, Volume: 43, Issue:11 Topics: Animals; Carbon Tetrachloride; Hepatic Stellate Cells; Liver; Liver Cirrhosis; Mice; Receptor, Transforming Growth Factor-beta Type I; Signal Transduction; Smad7 Protein; Transforming Growth Factor beta	2023