Page last updated: 2024-08-17

carbon tetrachloride and simvastatin

carbon tetrachloride has been researched along with simvastatin in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (42.86)29.6817
2010's4 (57.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Abraldes, JG; Bosch, J; García-Calderó, H; García-Pagán, JC; Graupera, M; Rodríguez-Vilarrupla, A; Zafra, C1
Arkad'eva, AV; Baĭdiuk, EV; Morozov, VI; Okovityĭ, SV; Sakuta, GA; Shiriaeva, AP1
Arkadieva, A; Baidyuk, E; Morozov, V; Okovityy, S; Sakuta, G; Shiryaeva, A1
Bosch, J; García-Calderó, H; García-Cardeña, G; García-Pagán, JC; Gracia-Sancho, J; Russo, L1

Other Studies

7 other study(ies) available for carbon tetrachloride and simvastatin

ArticleYear
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Simvastatin treatment improves liver sinusoidal endothelial dysfunction in CCl4 cirrhotic rats.
    Journal of hepatology, 2007, Volume: 46, Issue:6

    Topics: Animals; Anticholesteremic Agents; Carbon Tetrachloride; Cyclic GMP; Liver; Liver Cirrhosis; Liver Diseases; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Perfusion; Phosphorylation; Rats; Rats, Wistar; Simvastatin

2007
[Hepatocyte mitochondrion respiratory chain in rats with experimental toxic hepatitis].
    Tsitologiia, 2007, Volume: 49, Issue:2

    Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochromes c; Dinitrophenols; Electron Transport; Ethanol; Hepatocytes; Malates; Male; Mitochondria; Oxygen Consumption; Pyruvic Acid; Rats; Rats, Wistar; Rotenone; Simvastatin

2007
Hepatocyte mitochondrion electron-transport chain alterations in CCl(4) and alcohol induced hepatitis in rats and their correction with simvastatin.
    Journal of bioenergetics and biomembranes, 2008, Volume: 40, Issue:1

    Topics: Animals; Anticholesteremic Agents; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Central Nervous System Depressants; Electron Transport; Electron Transport Complex I; Electron Transport Complex IV; Ethanol; Hepatitis, Alcoholic; Hepatitis, Animal; Hepatocytes; Male; Mitochondria, Liver; Oxygen Consumption; Rats; Rats, Wistar; Simvastatin

2008
Endothelial expression of transcription factor Kruppel-like factor 2 and its vasoprotective target genes in the normal and cirrhotic rat liver.
    Gut, 2011, Volume: 60, Issue:4

    Topics: Animals; Carbon Tetrachloride; Endothelium, Vascular; Gene Expression Regulation; Hemodynamics; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kruppel-Like Transcription Factors; Liver; Liver Cirrhosis, Experimental; Male; Portal Pressure; Rats; Rats, Wistar; Simvastatin

2011