Page last updated: 2024-08-17

carbon tetrachloride and promethazine

carbon tetrachloride has been researched along with promethazine in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199026 (86.67)18.7374
1990's1 (3.33)18.2507
2000's0 (0.00)29.6817
2010's3 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Glen, RC; Lowe, R; Mitchell, JB1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chiono, MP; Dianzani, MU; Gravela, E; Poli, G; Slater, TF1
Packer, JE; Slater, TF; Willson, RL1
Castro, JA; D'Acosta, N; de Castro, CR; de Fenos, OM; de Ferreyra, EC; Gómez, MI1
Lawson, TA; Pound, AW1
Masuda, Y; Nakamura, Y1
Biasi, F; Cheeseman, KH; Chiarpotto, E; Dianzani, MU; Esterbauer, H; Poli, G; Slater, TF1
Maruyama, M; Sato, Y1
Jose, PJ; Slater, TF2
Marchand, C; Nadeau, D1
Baccino, FM; Dianzani, MU; Rita, GA1
Plaa, GL; Rice, AJ1
Sawyer, BC; Slater, TF1
Kaszewska-Jablońska, I1
Cheeseman, KH; Reddrop, CJ; Slater, TF1
Glende, EA; Recknagel, RO; Waller, RL1
Slater, TF1
Reddrop, CJ; Riess, W; Slater, TF2
Castro, JA; de Toranzo, EG; Marzi, A1
REES, KR; SPECTOR, WG1
GALLAGHER, CH; REES, KR1
BALWANI, JH; CHITALE, GK; JOGLEKAR, GV1
BALWANI, JH; CHITALE, GK; JOGLEKAR, GV; KARANDIKAR, SM1
WIGGLESWORTH, JS1
AMER, S; PETZOLD, H; ZIMMERMANN, S1
AHMED, K; JUDAH, JD; MCLEAN, AE1

Other Studies

30 other study(ies) available for carbon tetrachloride and promethazine

ArticleYear
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Effects of carbon tetrachloride on isolated rat liver cells: stimulation of lipid peroxidation and inhibitory action of free-radical scavengers [proceedings].
    Biochemical Society transactions, 1978, Volume: 6, Issue:3

    Topics: Animals; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Free Radicals; In Vitro Techniques; Liver; Male; Peroxidases; Promethazine; Rats

1978
Reactions of the carbon tetrachloride-related peroxy free radical (CC13O.2) with amino acids: pulse radiolysis evidence.
    Life sciences, 1978, Dec-25, Volume: 23, Issue:26

    Topics: Amino Acids; Carbon Tetrachloride; Chemical Phenomena; Chemistry; Free Radicals; Promethazine; Spectrum Analysis

1978
Carbon tetrachloride induced polysome breakdown. Relative importance of lipid peroxidation and of binding to ribosomal components in the process.
    Research communications in chemical pathology and pharmacology, 1975, Volume: 10, Issue:1

    Topics: Animals; Antioxidants; Carbon Radioisotopes; Carbon Tetrachloride; Cystamine; Free Radicals; Hydrolyzable Tannins; In Vitro Techniques; Lipid Metabolism; Microsomes, Liver; Peroxides; Phenylenediamines; Polyribosomes; Promethazine; Rats; Ribosomes; Spectrophotometry, Ultraviolet; Time Factors; Vitamin E

1975
Reduction of carbon tetrachloride toxicity by prior administration of a single small dose in mice and rats.
    British journal of experimental pathology, 1975, Volume: 56, Issue:2

    Topics: Animals; Carbon Tetrachloride; Dimethylnitrosamine; Ether; Lethal Dose 50; Liver; Male; Mice; Premedication; Promethazine; Rats; Time Factors

1975
Effects of oxygen deficiency and calcium omission on carbon tetrachloride hepatotoxicity in isolated perfused livers from phenobarbital-pretreated rats.
    Biochemical pharmacology, 1990, Oct-15, Volume: 40, Issue:8

    Topics: Animals; Calcium; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; In Vitro Techniques; Liver; Liver Diseases; Male; Oxygen; Perfusion; Phenobarbital; Phenylenediamines; Promethazine; Rats; Rats, Inbred Strains

1990
Promethazine inhibits the formation of aldehydic products of lipid peroxidation but not covalent binding resulting from the exposure of rat liver fractions to CCl4.
    The Biochemical journal, 1989, Dec-01, Volume: 264, Issue:2

    Topics: Aldehydes; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cells, Cultured; Kinetics; Lipid Metabolism; Lipid Peroxidation; Liver; Male; Microsomes, Liver; Promethazine; Protein Binding; Proteins; Rats; Rats, Inbred Strains; Reference Values

1989
The inhibition of tryptophan pyrrolase synthesis in rat liver by carbon tetrachloride.
    Journal of biochemistry, 1972, Volume: 72, Issue:5

    Topics: Animals; Carbon Tetrachloride; Dactinomycin; Depression, Chemical; Enzyme Induction; Liver; Male; Nitriles; Promethazine; Rats; Triamcinolone Acetonide; Tryptophan; Tryptophan Oxygenase

1972
The stimulation of lipid peroxidation produced by dimethylnitrosamine in rat liver microsomes in vitro: the effects of promethazine and inhibitors of drug metabolism, and a comparison with previous studies using carbon tetrachloride.
    Xenobiotica; the fate of foreign compounds in biological systems, 1973, Volume: 3, Issue:6

    Topics: Animals; Binding Sites; Carbon Tetrachloride; Chloromercuribenzoates; Cytochrome P-450 Enzyme System; Female; Kinetics; Lipid Metabolism; Male; Microsomes, Liver; NAD; NADP; Nitrosamines; Proadifen; Promethazine; Protein Binding; Rats; Spectrophotometry; Spectrophotometry, Ultraviolet; Stimulation, Chemical; Time Factors

1973
Importance of the route of administration of ccl 4 in the protective effect of promethazine.
    Biochemical pharmacology, 1973, May-15, Volume: 22, Issue:10

    Topics: Alanine Transaminase; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Glucose-6-Phosphatase; In Vitro Techniques; Intestinal Absorption; Liver Diseases; Male; Promethazine; Rats; Time Factors

1973
Increased concentrations of malonaldehyde in the livers of rats treated with carbon tetrachloride.
    The Biochemical journal, 1972, Volume: 128, Issue:4

    Topics: Aldehydes; Animals; Carbon Tetrachloride; Liver; Malonates; Promethazine; Rats; Trichloroacetic Acid

1972
Further experiments on the action of CCl-4 on lysosomes in vitro.
    Enzymologia, 1965, Nov-06, Volume: 29, Issue:3

    Topics: Acid Phosphatase; Animals; Carbon Tetrachloride; Diphenhydramine; Edetic Acid; Glucuronidase; In Vitro Techniques; Liver; Lysosomes; Promethazine; Rats; Ribonucleases; Serum Albumin, Bovine; Sulfatases

1965
The role of triglyceride accumulation and of necrosis in the hemodynamic responses of the isolated perfused rat liver after administration of carbon tetrachloride.
    Toxicology and applied pharmacology, 1969, Volume: 14, Issue:1

    Topics: Acetates; Amides; Animals; Body Temperature; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Castration; Chemical and Drug Induced Liver Injury; Edetic Acid; Ethionine; Female; Hemodynamics; Hypothermia, Induced; Liver Circulation; Liver Diseases; Male; Methionine; Necrosis; Ovary; Perfusion; Promethazine; Quaternary Ammonium Compounds; Rats; Testosterone; Triglycerides

1969
The stimulatory effects of carbon tetrachloride on peroxidative reactions in rat liver fractions in vitro. Inhibitory effects of free-radical scavengers and other agents.
    The Biochemical journal, 1971, Volume: 123, Issue:5

    Topics: Aldehydes; Aniline Compounds; Animals; Carbon Tetrachloride; Deferoxamine; Edetic Acid; Female; Gallic Acid; Glycols; In Vitro Techniques; Inosine; Lipid Metabolism; Liver; Malonates; Microsomes, Liver; Peroxides; Polyethylenes; Promethazine; Rats; Vitamin E

1971
[Iron of the subcellular fractions of liver tissue. 3. Effect of promethazine on hepatocellular changes in carbon tetrachloride poisoning].
    Polskie Archiwum Medycyny Wewnetrznej, 1972, Volume: 48, Issue:6

    Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Iron; Liver; Necrosis; Promethazine; Rats; Subcellular Fractions

1972
Correlations between common tests for assessment of liver damage: indices of the hepatoprotective activity of promethazine in carbon tetrachloride hepatotoxicity.
    Cell biochemistry and function, 1983, Volume: 1, Issue:1

    Topics: Animals; Body Temperature; Carbon Tetrachloride; Fatty Liver; Lipid Metabolism; Lipid Peroxides; Liver; Male; Microsomes, Liver; Necrosis; Promethazine; Proteins; Rats; Respiration

1983
Carbon tetrachloride and bromotrichloromethane toxicity. Dual role of covalent binding of metabolic cleavage products and lipid peroxidation in depression of microsomal calcium sequestration.
    Biochemical pharmacology, 1983, May-15, Volume: 32, Issue:10

    Topics: Animals; Bromotrichloromethane; Calcium; Carbon Tetrachloride; Chloroform; Depression, Chemical; Lipid Metabolism; Lipid Peroxides; Male; Malondialdehyde; Microsomes, Liver; Promethazine; Rats; Rats, Inbred Strains

1983
Biochemical implications of current studies on vitamin E.
    Annals of the New York Academy of Sciences, 1982, Volume: 393

    Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Free Radicals; Liver; Membranes; Promethazine; Vitamin E

1982
Interactions of carbon tetrachloride and promethazine in the rat--I. Effects of promethazine on the concentrations of carbon tetrachloride in blood and liver, and on the production of chloroform.
    Biochemical pharmacology, 1981, Jun-15, Volume: 30, Issue:12

    Topics: Animals; Carbon Tetrachloride; Chloroform; Liver; Male; Promethazine; Rats; Time Factors

1981
Interactions of carbon tetrachloride and promethazine in the rat--II. Elimination of carbon tetrachloride and chloroform in expired air as indications of their metabolism in the intact animal.
    Biochemical pharmacology, 1981, Jun-15, Volume: 30, Issue:12

    Topics: Animals; Carbon Tetrachloride; Chloroform; Chromatography, Gas; Flame Ionization; Male; Promethazine; Rats; Respiration

1981
Promethazine administration to rats and CCl4 induced lipid peroxidation of liver microsomal lipids.
    Research communications in chemical pathology and pharmacology, 1980, Volume: 30, Issue:1

    Topics: Animals; Arachidonic Acids; Carbon Tetrachloride; Fatty Acids; In Vitro Techniques; Lipid Peroxides; Male; Microsomes, Liver; Phospholipids; Promethazine; Rats

1980
Reversible nature of liver cell damage due to carbon tetrachloride as demonstrated by the use of phenergan.
    Nature, 1961, May-27, Volume: 190

    Topics: Carbon Tetrachloride; Liver; Liver Diseases; Promethazine

1961
Levels of pyridine nucleotides in liver poisoning.
    Nature, 1960, Jul-09, Volume: 187

    Topics: Carbon Tetrachloride; Liver; Nucleosides; Nucleotides; Promethazine; Pyridines

1960
PROTECTION BY INDIGENOUS DRUGS AGAINST HEPATOTOXIC EFFECTS OF CARBON TETRACHLORIDE IN MICE.
    Acta pharmacologica et toxicologica, 1963, Volume: 20

    Topics: Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chlorpromazine; Hepatitis; Hepatitis A; Hepatitis, Animal; Medicine, Traditional; Mice; Pathology; Plants, Medicinal; Promethazine; Research; Toxicology

1963
PROTECTION BY INDIGENOUS DRUGS AGAINST HEPATOTOXIC EFFECTS OF CARBON TETRACHLORIDE - A LONG TERM STUDY.
    Acta pharmacologica et toxicologica, 1963, Volume: 20

    Topics: Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Hepatitis; Hepatitis A; Longitudinal Studies; Medicine, Traditional; Pharmacology; Plants, Medicinal; Promethazine; Rats; Research; Sex; Toxicology

1963
THE USE OF THE OSMIUM-ETHYL GALLATE TECHNIQUE IN THE STUDY OF CARBON TETRACHLORIDE LIVER INJURY.
    The Journal of pathology and bacteriology, 1964, Volume: 87

    Topics: Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Gallic Acid; Hepatitis; Osmium; Pathology; Pharmacology; Promethazine; Rats; Research; Toxicology

1964
[THE EFFECT OF DIFFERENT SUBSTANCES ON ACUTE CARBON TETRACHLORIDE NECROSIS OF THE RAT LIVER].
    Archiv fur Toxikologie, 1965, Feb-10, Volume: 20

    Topics: Aspartate Aminotransferases; Blood Chemical Analysis; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chlorpromazine; Hepatitis; Hepatitis A; Histocytochemistry; Liver; Necrosis; Pharmacology; Promethazine; Rats; Research; Reserpine; Toxicology

1965
PROTECTION PROVIDED AGAINST CARBON TETRACHLORIDE AND THIOACETAMIDE POISONING BY STROPHANTHIN-G.
    The Journal of pathology and bacteriology, 1965, Volume: 89

    Topics: Amides; Bilirubin; Blood Chemical Analysis; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Hepatitis; Hepatitis A; Isocitrate Dehydrogenase; Necrosis; Ouabain; Pathology; Pharmacology; Promethazine; Pyruvates; Rats; Research; Sulfhydryl Compounds; Thioacetamide; Toxicology; Transaminases

1965