Compounds > carbon tetrachloride
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carbon tetrachloride and pregnenolone carbonitrile

carbon tetrachloride has been researched along with pregnenolone carbonitrile in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's2 (40.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Drew, RT; Fouts, JR; Lo, RJ; Roth, RP1
Elrick, LJ; Goodwin, B; Haefner, D; Konstantinou, DK; Marek, CJ; Murray, GI; Sigalas, C; Tucker, SJ; Wright, MC1
Abe, T; Hosaka, T; Kodama, S; Okamura, M; Sasaki, T; Shizu, R; Yoshinari, K1

Other Studies

5 other study(ies) available for carbon tetrachloride and pregnenolone carbonitrile

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Dichloromethane inhalation, carboxyhemoglobin concentrations, and drug metabolizing enzymes in rabbits.
    Toxicology and applied pharmacology, 1975, Volume: 33, Issue:3

    Topics: Animals; Carbon Tetrachloride; Carboxyhemoglobin; Hemoglobins; Hydrocarbons, Chlorinated; Male; Methylcholanthrene; Methylene Chloride; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Pregnenolone Carbonitrile; Proadifen; Rabbits

1975
Pregnenolone-16alpha-carbonitrile inhibits rodent liver fibrogenesis via PXR (pregnane X receptor)-dependent and PXR-independent mechanisms.
    The Biochemical journal, 2005, May-01, Volume: 387, Issue:Pt 3

    Topics: Animals; Carbon Tetrachloride; Hepatocytes; Liver Cirrhosis; Male; Mice; Mice, Knockout; Pregnane X Receptor; Pregnenolone Carbonitrile; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid

2005
PXR Functionally Interacts with NF-κB and AP-1 to Downregulate the Inflammation-Induced Expression of Chemokine CXCL2 in Mice.
    Cells, 2020, 10-15, Volume: 9, Issue:10

    Topics: Animals; Anti-Inflammatory Agents; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chemokine CXCL2; Disease Models, Animal; Gene Expression Regulation; HEK293 Cells; Humans; Inflammation; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Pregnane X Receptor; Pregnenolone Carbonitrile; Protein Binding; Transcription Factor AP-1; Tumor Necrosis Factor-alpha

2020