carbon tetrachloride has been researched along with oleanolic acid in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.57) | 18.7374 |
| 1990's | 6 (21.43) | 18.2507 |
| 2000's | 8 (28.57) | 29.6817 |
| 2010's | 10 (35.71) | 24.3611 |
| 2020's | 3 (10.71) | 2.80 |
| Authors | Studies |
|---|---|
| Balanehru, S; Nagarajan, B | 1 |
| Chuang, CH; Lin, CC; Liu, SY; Yen, MH | 1 |
| Amagaya, S; Hikino, H; Kiso, Y; Ogihara, Y | 1 |
| Arao, T; Kinjo, J; Miyao, H; Nohara, T; Udayama, M | 1 |
| Jeong, HG; Park, HY | 1 |
| Hartley, DP; Liu, J; Liu, Y | 1 |
| Jeong, HG | 1 |
| Ko, KM; Pak, WF; Wu, WK; Yim, TK | 1 |
| Chen, Y; Liu, J; Xu, H; Yang, X; Zhao, X | 1 |
| Cho, SY; Choi, JW; Kim, NY; Kim, SH; Kim, SJ; Lee, JS; Lee, MK; Park, HJ; Park, MJ | 1 |
| Chen, J; Fang, F; Gao, J; Tang, XH; Xu, LZ; Xu, Q; Zhao, XN | 1 |
| Baiuomy, AR; El-Sayed, MM; Marzouk, MS; Mohamed, MA; Moharram, FA | 1 |
| Cheng, YA; Dang, SS; Li, ZF; Liu, ZG; Song, P; Wang, BF | 1 |
| Kong, XW; Sun, Y; Wu, LM; Wu, XX; Xu, Q; Zhang, YH | 1 |
| Chao, JC; Chu, CC; Lin, YH; Tsai, YH; Wu, SJ | 1 |
| Chang, CC; Chao, JC; Tam, KW; Tsai, YH; Wu, SJ | 1 |
| Baev, DS; Bessergeneva, EP; Glukhov, BM; Nepomnyaschikh, GI; Semenov, DE; Sorokina, IV; Tolstikova, TG; Zhukova, NA | 1 |
| Huang, XT; Li, N; Li, YY; Liu, CH; Mi, SQ; Wang, NS; Zheng, X | 1 |
| Feng, Y; Li, S; Li, X; Li, Y; Liu, L; Lv, S; Zhang, K | 1 |
| Fang, H; Qiu, X; Sun, Y; Wang, J; Wang, X; Wang, Z; Xia, Z; Zhang, F | 1 |
| Arya, PV; Dobhal, MP; Gupta, RS; Sharma, A; Singh, D | 1 |
| Baiev, DS; Biryukova, MS; Ivanova, EP; Nepomnyashchikh, GI; Semenov, DE; Sorokina, IV; Tolstikova, TG; Zhukova, NA | 1 |
| Cusimano, FA; Getachew, Y; Gopal, P; Reisman, SA; Shay, JW | 1 |
| Jiang, T; Li, G; Peng, W; Sun, W; Yu, R; Yu, Z | 1 |
| Chen, Y; Li, Y; Lin, L; Que, R; Shen, Y; Yan, N | 1 |
| Chen, Y; Li, Y; Lin, L; Liu, X; Que, R; Shi, Z; Zhang, K; Zhou, M | 1 |
| Liu, S; Qu, H; Wang, Z; Xin, C | 1 |
| Chen, Y; Li, Y; Lin, L; Que, R; Zhang, N; Zhou, M | 1 |
28 other study(ies) available for carbon tetrachloride and oleanolic acid
| Article | Year |
|---|---|
Protective effect of oleanolic acid and ursolic acid against lipid peroxidation.
Topics: Adenosine Diphosphate; Animals; Antineoplastic Agents, Phytogenic; Ascorbic Acid; Carbon Tetrachloride; Iron; Lipid Peroxidation; Microsomes, Liver; Oleanolic Acid; Rats; Triterpenes; Ursolic Acid | 1991 |
Evaluation of root quality of Bupleurum species by TLC scanner and the liver protective effects of "xiao-chai-hu-tang" prepared using three different Bupleurum species.
Topics: Animals; Calibration; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chromatography, Thin Layer; Drugs, Chinese Herbal; Liver; Liver Diseases; Male; Oleanolic Acid; Plant Extracts; Rats; Rats, Inbred Strains; Sapogenins; Saponins | 1991 |
Antihepatotoxic actions of papyriogenins and papyriosides, triterpenoids of Tetrapanax papyriferum leaves.
Topics: Alanine Transaminase; Animals; Carbon Tetrachloride; Cells, Cultured; Galactosamine; Liver; Oleanolic Acid; Plants, Medicinal; Rats; Sapogenins; Structure-Activity Relationship; Triterpenes | 1984 |
Kaikasaponin III and soyasaponin I, major triterpene saponins of Abrus cantoniensis, act on GOT and GPT: influence on transaminase elevation of rat liver cells concomitantly exposed to CCl4 for one hour.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbohydrate Sequence; Carbon Tetrachloride; Liver; Male; Medicine, Chinese Traditional; Molecular Sequence Data; Oleanolic Acid; Plants, Medicinal; Rats; Rats, Wistar; Saponins | 1998 |
The prevention of carbon tetrachloride-induced hepatotoxicity in mice by alpha-hederin: inhibiton of cytochrome P450 2E1 expression.
Topics: Animals; Carbon Tetrachloride; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Drugs, Chinese Herbal; Injections, Intraperitoneal; Injections, Subcutaneous; Liver; Male; Mice; Mice, Inbred BALB C; Microsomes, Liver; Oleanolic Acid; Saponins | 1998 |
Protection against carbon tetrachloride hepatotoxicity by oleanolic acid is not mediated through metallothionein.
Topics: Animals; Carbon Tetrachloride; Dose-Response Relationship, Drug; Drug Interactions; Liver; Male; Metallothionein; Mice; Mice, Knockout; Oleanolic Acid; Rats; Rats, Sprague-Dawley | 1998 |
Inhibition of cytochrome P450 2E1 expression by oleanolic acid: hepatoprotective effects against carbon tetrachloride-induced hepatic injury.
Topics: Alanine Transaminase; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutathione; Glutathione Transferase; L-Lactate Dehydrogenase; Liver; Liver Diseases; Male; Mice; Mice, Inbred BALB C; Microsomes, Liver; Oleanolic Acid | 1999 |
Hepatoprotective action of an oleanolic acid-enriched extract of Ligustrum lucidum fruits is mediated through an enhancement on hepatic glutathione regeneration capacity in mice.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Female; Fruit; Hepatocytes; Liver; Mice; Mice, Inbred BALB C; Oleaceae; Oleanolic Acid; Phytotherapy; Plant Extracts | 2001 |
Oleanolic acid nanosuspensions: preparation, in-vitro characterization and enhanced hepatoprotective effect.
Topics: Administration, Oral; Alanine Transaminase; Animals; Calorimetry, Differential Scanning; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chemistry, Pharmaceutical; China; Dosage Forms; Drug Evaluation, Preclinical; Hepatocytes; Injections, Subcutaneous; Liver Diseases; Malondialdehyde; Medicine, Chinese Traditional; Mice; Nanostructures; Oleanolic Acid; Particle Size; Solubility; Suspensions; Triterpenes; X-Ray Diffraction | 2005 |
Momordin Ic and oleanolic acid from Kochiae Fructus reduce carbon tetrachloride-induced hepatotoxicity in rats.
Topics: Administration, Oral; Animals; Carbon Tetrachloride; Chenopodiaceae; Glutathione; Liver; Male; Oleanolic Acid; Protective Agents; Random Allocation; Rats; Rats, Sprague-Dawley | 2005 |
Hepatoprotection of oleanolic acid is related to its inhibition on mitochondrial permeability transition.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Calcium; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; In Vitro Techniques; Male; Membrane Potentials; Mice; Mice, Inbred ICR; Mitochondria, Liver; Mitochondrial Swelling; Oleanolic Acid | 2005 |
Phytochemical constituents and hepatoprotective activity of Viburnum tinus.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Drug Evaluation, Preclinical; Iridoids; Lipid Peroxides; Liver; Male; Molecular Structure; Nitric Oxide; Oleanolic Acid; Plant Extracts; Plants, Medicinal; Protective Agents; Rats; Saponins; Viburnum | 2005 |
Inhibitory effects of saikosaponin-d on CCl4-induced hepatic fibrogenesis in rats.
Topics: Alanine Transaminase; Animals; Carbon Tetrachloride; Hyaluronic Acid; Laminin; Liver; Liver Cirrhosis, Experimental; Male; Oleanolic Acid; Rats; Rats, Sprague-Dawley; Saponins; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2007 |
A novel synthetic oleanolic acid derivative (CPU-II2) attenuates liver fibrosis in mice through regulating the function of hepatic stellate cells.
Topics: Actins; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cell Line; Cell Survival; Collagen Type I; Collagen Type I, alpha 1 Chain; Down-Regulation; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Male; MAP Kinase Signaling System; Mice; Mice, Inbred ICR; Oleanolic Acid; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Tissue Inhibitor of Metalloproteinase-1 | 2008 |
Curcumin or saikosaponin a improves hepatic antioxidant capacity and protects against CCl4-induced liver injury in rats.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Curcumin; Glutathione; Lipids; Liver; Liver Diseases; Male; Oleanolic Acid; Rats; Rats, Sprague-Dawley; Saponins; Superoxide Dismutase | 2008 |
Curcumin and saikosaponin a inhibit chemical-induced liver inflammation and fibrosis in rats.
Topics: Animals; Anti-Inflammatory Agents; Bupleurum; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Collagen; Curcuma; Curcumin; Cytokines; Dietary Supplements; Drug Therapy, Combination; Fibrosis; Hydroxyproline; Inflammation; Liver; Male; NF-kappa B; Oleanolic Acid; Phytotherapy; Plant Extracts; Plant Roots; Random Allocation; Rats; Rats, Sprague-Dawley; Rhizome; Saponins; Transforming Growth Factor beta1 | 2010 |
Effect of triterpene derivatives on the total hepatocyte count in the liver of rats with toxic hepatitis.
Topics: Alanine Transaminase; Alkaline Phosphatase; Amides; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Cell Count; Cell Proliferation; Chemical and Drug Induced Liver Injury; Ethanol; Female; Hepatocytes; L-Lactate Dehydrogenase; Liver; Oleanolic Acid; Rats | 2012 |
[The anti-portal hypertension effect of oleanolic acid in CCl4-induced cirrhosis rats].
Topics: Animals; Body Weight; Carbon Tetrachloride; Disease Models, Animal; Hypertension, Portal; Liver; Liver Cirrhosis, Experimental; Liver Function Tests; Male; Malondialdehyde; Nitric Oxide; Nitric Oxide Synthase Type III; Oleanolic Acid; Phytotherapy; Plant Extracts; Protective Agents; Rats; Rats, Sprague-Dawley | 2012 |
Preparation, characterization, and in vivo pharmacokinetics of nanostructured lipid carriers loaded with oleanolic acid and gentiopicrin.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Female; Iridoid Glucosides; Lipids; Liver; Male; Mice; Nanostructures; Oleanolic Acid; Particle Size; Rats; Rats, Sprague-Dawley | 2013 |
The protective effect of Esculentoside A on experimental acute liver injury in mice.
Topics: Animals; Apoptosis; Carbon Tetrachloride; Cell Proliferation; Chemical and Drug Induced Liver Injury; Immunohistochemistry; In Situ Nick-End Labeling; Inflammation; Interleukin-1beta; Interleukin-6; Mice; Oleanolic Acid; Oxidative Stress; Reactive Oxygen Species; Saponins; Signal Transduction; Sincalide | 2014 |
Modulatory potential of α-amyrin against hepatic oxidative stress through antioxidant status in Wistar albino rats.
Topics: Alstonia; Animals; Carbon Tetrachloride; Liver; Male; Oleanolic Acid; Oxidative Stress; Plant Bark; Rats, Wistar | 2015 |
Hepatoprotective properties of betulonic acid amide and heptral in toxic liver injury induced by carbon tetrachloride in combination with ethanol.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Ethanol; Female; Liver; Oleanolic Acid; Rats; Rats, Wistar | 2015 |
The Synthetic Triterpenoid RTA 405 (CDDO-EA) Halts Progression of Liver Fibrosis and Reduces Hepatocellular Carcinoma Size Resulting in Increased Survival in an Experimental Model of Chronic Liver Injury.
Topics: Animals; Carbon Tetrachloride; Cell Line, Tumor; Cytochrome P-450 CYP2E1; Cytokines; Disease Progression; Humans; Liver Cirrhosis, Experimental; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Oleanolic Acid | 2016 |
Pharmacokinetics in Vitro and in Vivo of Two Novel Prodrugs of Oleanolic Acid in Rats and Its Hepatoprotective Effects against Liver Injury Induced by CCl4.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Liver; Male; Malondialdehyde; Oleanolic Acid; Prodrugs; Protective Agents; Rats; Rats, Wistar; Tissue Distribution | 2016 |
Saikosaponin‑d alleviates carbon‑tetrachloride induced acute hepatocellular injury by inhibiting oxidative stress and NLRP3 inflammasome activation in the HL‑7702 cell line.
Topics: Apoptosis; Carbon Tetrachloride; Cell Line; Cell Survival; Chemical and Drug Induced Liver Injury; Cytokines; Inflammasomes; Inflammation Mediators; Liver; Malondialdehyde; NLR Family, Pyrin Domain-Containing 3 Protein; Oleanolic Acid; Oxidative Stress; Saponins | 2018 |
Saikosaponin-d protects against liver fibrosis by regulating the estrogen receptor-β/NLRP3 inflammasome pathway.
Topics: Animals; Carbon Tetrachloride; Cells, Cultured; Estrogen Receptor beta; Inflammasomes; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Oleanolic Acid; Protective Agents; Saponins | 2021 |
The novel nanocomplexes containing deoxycholic acid-grafted chitosan and oleanolic acid displays the hepatoprotective effect against CCl
Topics: Administration, Oral; Animals; Biological Availability; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chitosan; Deoxycholic Acid; Gene Expression Regulation; Humans; Male; Mice; Nanocomposites; NF-kappa B; Oleanolic Acid; Oxidative Stress; Signal Transduction | 2021 |
Saikosaponin-d alleviates hepatic fibrosis through regulating GPER1/autophagy signaling.
Topics: Animals; Autophagy; Carbon Tetrachloride; Cells, Cultured; China; Fibrosis; Hepatic Stellate Cells; Humans; Liver; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Oleanolic Acid; Receptors, Estrogen; Receptors, G-Protein-Coupled; Saponins; Signal Transduction; Transforming Growth Factor beta | 2021 |