Compounds > carbon tetrachloride
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carbon tetrachloride and nadp

carbon tetrachloride has been researched along with nadp in 106 studies

Research

Studies (106)

TimeframeStudies, this research(%)All Research%
pre-199081 (76.42)18.7374
1990's18 (16.98)18.2507
2000's2 (1.89)29.6817
2010's5 (4.72)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ghosh, JJ; Mitra, G; Poddar, MK1
Uehleke, H; Werner, T1
Tappel, AL; Taylor, SL1
Burdino, E; Sawyer, BC; Slater, TF; Torrielli, MV; Ugazio, G1
Chen, WJ; Chi, EY; Smuckler, EA1
Sawyer, BC; Slater, TF3
Gillette, JR; Krishna, G; Sipes, IG1
Reid, AM; Slater, TF1
Masuda, Y; Murano, T1
Davis, ER; Floyd, RA; Janzen, EG; McCay, PB; Poyer, JL1
Shires, TK1
Recknagel, RO; Willis, RJ1
Chignell, CF; Kalyanaraman, B; Mason, RP; Perez-Reyes, E; Philpot, RM; Wolf, CR1
Kamataki, T; Kato, R; Sugiura, M; Yamazoe, Y1
Castro, JA; Díaz Gómez, MI; Villarruel, MC1
Khan, S; Lauriault, VV; O'Brien, PJ1
Barth, A; Bernst, M1
Advani, S; Bidlack, WR; Riebow, JF; Tortoriello, PJ1
Ishii, S; Okada, S; Tezuka, M1
Kostyuk, VA; Potapovich, AI; Tereshchenko, SM1
Albano, E; Basaga, H; Busolin, D; Carini, R; Comoglio, A; Leonarduzzi, G; Magistretti, MJ; Morazzoni, P; Poli, G; Tomasi, A1
Ingelman-Sundberg, M; Persson, JO; Terelius, Y1
Chen, NQ; Holtzman, JL; Srivastava, SP1
Fujii, K; Kawamoto, M; Morio, M; Sato, N; Yuge, O1
Advani, SV; Bidlack, WR; Riebow, JF; Tortoriello, P1
Smith, LL1
Beaune, P; Descatoire, V; Labbe, G; Larrey, D; Letteron, P; Pessayre, D1
Fujii, K; Morio, M; Sato, N; Yuge, O1
Castro, GD; Castro, JA; Díaz Gómez, MI1
Afanas'ev, IB; Brodskii, AV; Dorozhko, AI; Kostyuk, VA; Potapovitch, AI1
Delaforge, M; Jaouen, M; Jollès, P; Mansuy, D; Migliore-Samour, D1
de Groot, H; Noll, T; Tölle, T1
Boigegrain, RA; Cambon-Gros, C; Deltour, P; Fernandez, Y; Mitjavila, S1
Button, J; Clawson, GA; Geller, DA; Hammock, BD; Loury, DN; Moody, DE; Smuckler, EA; Taylor, LA1
Coleman, JB; Condie, LW; Lamb, RG1
Lange, R; Larroque, C1
Head, B; James, JL; Moody, DE; Smuckler, EA; Woo, CH1
de Groot, H; Noll, T; Sies, H1
Kenel, MF; Kulkarni, AP1
Davis, DC; Gillette, JR; Sasame, HA1
Hellmer, KH; Tabarelli, S; Uehleke, H1
Hellmer, KH; Tabarelli-Poplawski, S; Uehleke, H1
Jose, PJ; Slater, TF1
Hasumura, Y; Lieber, CS; Teschke, R1
Matsuoka, S; Oama, H; Tahara, K1
Brody, TM; Gibb, JW1
Schnitger, F; Uehleke, H1
Wills, ED1
Gillette, JR2
Glende, EA; Recknagel, RO1
Uehleke, H1
Chen, C; Lin, CC1
Davis, DC; Gillette, JR; Gram, TE; Reagan, RL; Schroeder, DH1
Brodie, BB; Cho, AK; Krishna, G; Reid, WD1
Arvela, P; Vorne, M1
Slater, TF; Torrielli, MV1
Heni, N1
Jacobson, M; Kuntzman, R; Levin, W1
Gerdes, H; Littmann, KP; Spuck, W1
McIntosh, DA; Topham, JC1
Carter, EA; Isselbacher, KJ1
Nachtomi, E1
Athanassopoulos, S; Hellmer, KH; Murray, RE; Reiner, O; Uehleke, H1
Gillette, JR; Krishna, G; Maling, HM; Sipes, IG; Stripp, B1
Glende, EA1
Kamm, JJ; Szuna, A1
Bernacchi, AS; Castro, JA; de Castro, CR; Fernández, G; Villarruel, MC1
Davis, ER; Janzen, EG; Lai, EK; McCay, PB; Poyer, JL1
Hodgson, E; Kulkarni, AP1
King, MM; Lai, EK; McCay, PB; Poyer, JL1
Gadeholt, G1
Kuriyama, K; Nakashima, T; Takino, T1
George, JW; Pohl, LR1
Kappus, H; Muliawan, H1
Rauckman, EJ; Rosen, GM1
Lesca, P; Liu, KT1
Moore, L; Ray, P1
Lamb, RG; Schwertz, DW1
de Groot, H; Haas, W1
Beer, DG; Grubbs, JH; Hjelle, JJ; Petersen, DR1
Kitta, D; Kunz, W; Schwarz, M; Tennekes, HA; Uehleke, H1
Castro, JA; Diaz Gomez, MI1
Ahr, HJ; King, LJ; Nastainczyk, W; Ullrich, V1
Harrelson, WG; Kalyanaraman, B; Mason, RP; Nastainczyk, WM; Philpot, RM; Wolf, CR1
Castro, GD; Castro, JA; de Mecca, MM; Díaz Gómez, MI1
Crossley, C; Janzen, EG; McCay, PB; Poyer, JL; West, MS1
Dhawan, D; Goel, A1
Ip, SP; Ko, KM1
Nakajin, S; Shinoda, M; Toyoshima, S; Uchida, M1
Chun, YJ; Jeong, TC; Kim, HJ; Kim, SI; Park, JD; Roh, JK1
Chen, G; Connor, HD; Janzen, EG; Mason, RP; Poyer, JL; Thurman, RG1
Gervasi, PG; Longo, V; Marini, S; Mazzaccaro, A1
Fung, PC; Zhu, W1
Dash, D; Dey, A; Dhawan, A; Parmar, D; Seth, PK1
BLUME, E; FRUNDER, H; KLUGE, H1
KANICS, L; RUBINSTEIN, D1
SLATER, TF1
Kondeva-Burdina, MS; Krasteva, IN; Mitcheva, MK; Nikolov, SD; Simeonova, RL; Vitcheva, VB1
Bag, PP; Hodage, A; Iwaoka, M; Jain, VK; Prabhu, P; Priyadarsini, KI; Singh, BG1
Cui, W; Ibi, M; Iwata, K; Katsuyama, M; Matsumoto, M; Matsuno, K; Torok, NJ; Yabe-Nishimura, C; Zhang, J; Zhu, K1
Guelfi, M; Maioli, MA; Medeiros, HC; Mingatto, FE; Moreira, PR; Pereira, FT1
Fukuishi, N; Miura, N; Nonogaki, T; Onosaka, S; Usuda, H; Yoshioka, H1

Reviews

4 review(s) available for carbon tetrachloride and nadp

ArticleYear
The response of the lung to foreign compounds that produce free radicals.
    Annual review of physiology, 1986, Volume: 48

    Topics: Air Pollutants; Animals; Bleomycin; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; DNA; Dogs; Free Radicals; Haplorhini; Humans; Hydrogen Peroxide; In Vitro Techniques; Lipid Peroxides; Lung; Lung Diseases; Mice; NADP; Nitrofurantoin; Nitrous Oxide; Oxidation-Reduction; Ozone; Paraquat; Rats; Superoxides; Thiourea

1986
Cytochrome P-450 and its role in drug metabolism.
    Annual review of pharmacology, 1972, Volume: 12

    Topics: Adrenalectomy; Animals; Carbon Tetrachloride; Cytochromes; Dealkylation; Deamination; Enzyme Induction; Female; Glucocorticoids; Hydroxylation; Male; Mice; Microsomes, Liver; NADP; Oxidation-Reduction; Oxidoreductases; Oxygen Consumption; Pharmaceutical Preparations; Phenobarbital; Phospholipids; Polycyclic Compounds; Pseudomonas; Rats; Sex Factors; Spectrum Analysis; Spironolactone; Ultraviolet Rays

1972
Cytochrome p450: the tip of another iceberg.
    Food and cosmetics toxicology, 1970, Volume: 8, Issue:3

    Topics: Carbon Tetrachloride; Cytochromes; Enzymes; Microsomes; Microsomes, Liver; NAD; NADP

1970
Factors affecting drug metabolism.
    Annals of the New York Academy of Sciences, 1971, Jul-06, Volume: 179

    Topics: Adrenalectomy; Age Factors; Animals; Carbon Monoxide; Carbon Tetrachloride; Circadian Rhythm; Cytochromes; Dealkylation; Deamination; Enzyme Induction; Female; Half-Life; Humans; Hydrocortisone; Kinetics; Liver Circulation; Male; Mathematics; Metabolism; Mice; Microsomes, Liver; Mitochondria, Muscle; Mixed Function Oxygenases; Models, Biological; Morphinans; Myocardium; NAD; NADP; Oxidation-Reduction; Oxidoreductases; Oxygen; Pharmaceutical Preparations; Protein Binding; Rats

1971

Other Studies

102 other study(ies) available for carbon tetrachloride and nadp

ArticleYear
Effect of delta9-tetrahydrocannabinol on rat liver microsomal lipid peroxidation.
    Toxicology and applied pharmacology, 1975, Volume: 34, Issue:3

    Topics: Animals; Cannabis; Carbon Tetrachloride; Dronabinol; In Vitro Techniques; Lipid Metabolism; Male; Microsomes, Liver; NADP; Peroxides; Rats; Time Factors

1975
A comparative study on the irreversible binding of labeled halothane trichlorofluoromethane, chloroform, and carbon tetrachloride to hepatic protein and lipids in vitro and in vivo.
    Archives of toxicology, 1975, Dec-18, Volume: 34, Issue:4

    Topics: 1-Propanol; Aerobiosis; Age Factors; Anaerobiosis; Animals; Carbon Tetrachloride; Chloroform; Cobalt; Cytochrome P-450 Enzyme System; Endoplasmic Reticulum; Halothane; Humans; In Vitro Techniques; Lipid Metabolism; Liver; Methylcholanthrene; Mice; Microsomes, Liver; Mitochondria, Liver; NADP; Phenobarbital; Protein Binding; Rabbits; Rats; Species Specificity

1975
Effect of dietary antioxidants and phenobarbital pretreatment on microsomal lipid peroxidation and activation by carbon tetrachloride.
    Life sciences, 1976, Oct-15, Volume: 19, Issue:8

    Topics: Animals; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Diet; Fatty Acids; Kinetics; Lipid Metabolism; Male; Microsomes, Liver; NADP; NADPH-Ferrihemoprotein Reductase; Peroxidases; Phenobarbital; Rats; Selenium; Vitamin E

1976
Long-range effects of products of carbon tetrachloride-stimulated lipid peroxidation.
    Biochemical Society transactions, 1976, Volume: 4, Issue:2

    Topics: Animals; Capillary Permeability; Carbon Tetrachloride; Hemolysis; Lipid Metabolism; Male; NADP; Peroxides; Platelet Aggregation; Prostaglandins; Rats

1976
Carbon tetrachloride-induced changes in mixed function oxidases and microsomal cytochromes in the rat lung.
    Laboratory investigation; a journal of technical methods and pathology, 1977, Volume: 36, Issue:4

    Topics: Administration, Oral; Aerosols; Aniline Compounds; Animals; Carbon Tetrachloride; Cytochromes; Lung; Male; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidoreductases; Oxidoreductases, N-Demethylating; Rats; Time Factors

1977
The effects of CCl4 on the content of nicotinamide adenine dinucleotide phosphate in rat liver.
    Chemico-biological interactions, 1977, Volume: 16, Issue:3

    Topics: Animals; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Female; Kinetics; Liver; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Rats; Time Factors

1977
Bioactivation of carbon tetrachloride, chloroform and bromotrichloromethane: role of cytochrome P-450.
    Life sciences, 1977, May-01, Volume: 20, Issue:9

    Topics: Allylisopropylacetamide; Animals; Bromotrichloromethane; Carbon Monoxide; Carbon Tetrachloride; Chloroform; Cytochrome P-450 Enzyme System; Glutathione; Immune Sera; In Vitro Techniques; Male; Microsomes, Liver; NADP; NADPH-Ferrihemoprotein Reductase; Nitrogen; Proadifen; Protein Binding; Rats

1977
Some effects of ethanol in vivo and in vitro on lipid peroxidation [proceedings].
    Biochemical Society transactions, 1977, Volume: 5, Issue:5

    Topics: Animals; Carbon Tetrachloride; Ethanol; Lipid Metabolism; Male; Malondialdehyde; Microsomes, Liver; NADP; Peroxides; Rats

1977
Carbon tetrachloride-induced lipid peroxidation of rat liver microsomes in vitro.
    Biochemical pharmacology, 1977, Dec-01, Volume: 26, Issue:23

    Topics: Animals; Antioxidants; Buffers; Carbon Tetrachloride; Female; Hemeproteins; Hydrogen-Ion Concentration; In Vitro Techniques; Lipid Metabolism; Malondialdehyde; Methane; Microsomes, Liver; NADP; Peroxides; Radiation-Protective Agents; Rats; Time Factors

1977
Spin-trapping of the trichloromethyl radical produced during enzymic NADPH oxidation in the presence of carbon tetrachloride or bromotrichloromethane.
    Biochimica et biophysica acta, 1978, Mar-20, Volume: 539, Issue:3

    Topics: Animals; Bromotrichloromethane; Carbon Tetrachloride; Chloroform; Computers; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Male; Microsomes, Liver; Models, Chemical; NADP; Oxidation-Reduction; Rats; Spin Labels

1978
Lipoperoxidative effects on liver rough microsomal membranes and the ribosome-membrane complex: studies in vitro and in vivo with chemical carcinogens and carbon tetrachloride.
    Laboratory investigation; a journal of technical methods and pathology, 1978, Volume: 38, Issue:6

    Topics: Aflatoxins; Amino Acids; Animals; Carbon Tetrachloride; Carcinogens; Dimethylnitrosamine; In Vitro Techniques; Liver; Male; Membrane Lipids; Membranes; Microsomes, Liver; NADP; p-Dimethylaminoazobenzene; Potassium; Rats; Ribosomes

1978
Potentiation by carbon tetrachloride of NADPH-dependent lipid peroxidation in lung microsomes.
    Toxicology and applied pharmacology, 1979, Volume: 47, Issue:1

    Topics: Animals; Calcium; Carbon Tetrachloride; In Vitro Techniques; Kinetics; Lipid Metabolism; Lung; Male; Microsomes; Microsomes, Liver; NADP; Oxidation-Reduction; Peroxides; Rats

1979
Characterization of the free radical formed in aerobic microsomal incubations containing carbon tetrachloride and NADPH.
    Biochemical and biophysical research communications, 1979, Aug-28, Volume: 89, Issue:4

    Topics: Aerobiosis; Animals; Carbon Tetrachloride; Electron Spin Resonance Spectroscopy; Free Radicals; Lipoxygenase; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Rats

1979
The apparent loss of cytochrome P-450 associated with metabolic activation of carbon tetrachloride.
    Japanese journal of pharmacology, 1979, Volume: 29, Issue:5

    Topics: Animals; Carbon Monoxide; Carbon Tetrachloride; Chloroform; Cytochrome P-450 Enzyme System; In Vitro Techniques; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Rats; Viologens

1979
The nature of the in vitro irreversible binding of carbon tetrachloride to microsomal lipids.
    Toxicology and applied pharmacology, 1975, Volume: 33, Issue:1

    Topics: Anaerobiosis; Animals; Carbon Tetrachloride; Chlorine; Chromatography, Gas; Chromatography, Thin Layer; Cytochrome P-450 Enzyme System; Cytochrome Reductases; In Vitro Techniques; Lipid Metabolism; Male; Microsomes, Liver; NADP; Radioisotopes; Rats

1975
Hepatocyte cytotoxicity induced by various hepatotoxins mediated by cytochrome P-450IIE1: protection with diethyldithiocarbamate administration.
    Chemico-biological interactions, 1992, Volume: 81, Issue:3

    Topics: Animals; Carbon Disulfide; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Disulfiram; Ditiocarb; Liver Diseases; Male; Microsomes, Liver; NADP; Oxidoreductases, N-Demethylating; Pyrazoles; Rats; Rats, Inbred Strains

1992
Influence of bile acids on stimulated lipid peroxidation and hydrogen peroxide production in rat liver microsomes.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 1992, Volume: 44, Issue:7

    Topics: Animals; Bile Acids and Salts; Carbon Tetrachloride; Cholesterol; Cytochrome P-450 Enzyme System; Ferrous Compounds; Hydrogen Peroxide; Lipid Peroxidation; Male; Microsomes, Liver; NADP; Rats; Rats, Wistar; Thiobarbiturates

1992
The anomaly of pyridine nucleotide synergism in carbon tetrachloride metabolism.
    Free radical biology & medicine, 1991, Volume: 10, Issue:6

    Topics: Animals; Carbon Tetrachloride; Drug Synergism; Male; Microsomes, Liver; NADP; Pyrophosphatases; Rats; Rats, Inbred Strains; Substrate Specificity

1991
Chromium (III) decreases carbon tetrachloride-originated trichloromethyl radical in mice.
    Journal of inorganic biochemistry, 1991, Volume: 44, Issue:4

    Topics: Animals; Carbon Tetrachloride; Chromium; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Lipid Peroxidation; Male; Mice; Microsomes, Liver; NADP; NADPH-Ferrihemoprotein Reductase

1991
4-(4-R-phenylamino)-5-methoxy-1,2-benzoquinones are new selective inhibitors of carbon tetrachloride-initiated free radical reactions in liver.
    Biochemistry international, 1991, Volume: 25, Issue:1

    Topics: Animals; Benzoquinones; Carbon Tetrachloride; Free Radicals; Lipid Peroxidation; Microsomes, Liver; NADP; Rats; Rats, Inbred Strains

1991
Studies on the antioxidant and free radical scavenging properties of IdB 1016 a new flavanolignan complex.
    Free radical research communications, 1990, Volume: 11, Issue:1-3

    Topics: Administration, Oral; Animals; Antioxidants; Ascorbic Acid; Benzene Derivatives; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Free Radicals; Iron; Lipid Peroxidation; Male; Malondialdehyde; Microsomes, Liver; NADH Dehydrogenase; NADP; Oxidation-Reduction; Phosphatidylcholines; Rats; Rats, Inbred Strains; Silymarin

1990
Cytochrome P-450-dependent formation of reactive oxygen radicals: isozyme-specific inhibition of P-450-mediated reduction of oxygen and carbon tetrachloride.
    Xenobiotica; the fate of foreign compounds in biological systems, 1990, Volume: 20, Issue:9

    Topics: Animals; Carbon Tetrachloride; Cimetidine; Cytochrome P-450 Enzyme System; Free Radicals; Hydrogen Peroxide; Imidazoles; In Vitro Techniques; Isoenzymes; Male; Microsomes, Liver; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Oxidoreductases; Oxygen Consumption; Rats; Rats, Inbred Strains

1990
The in vitro NADPH-dependent inhibition by CCl4 of the ATP-dependent calcium uptake of hepatic microsomes from male rats. Studies on the mechanism of the inactivation of the hepatic microsomal calcium pump by the CCl3.radical.
    The Journal of biological chemistry, 1990, May-25, Volume: 265, Issue:15

    Topics: Animals; Calcium; Calcium-Transporting ATPases; Carbon Monoxide; Carbon Radioisotopes; Carbon Tetrachloride; Kinetics; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Rats

1990
Paraquat inhibits the lipid peroxidation caused by carbon tetrachloride in guinea pig liver microsome.
    Research communications in chemical pathology and pharmacology, 1990, Volume: 70, Issue:1

    Topics: Animals; Carbon Tetrachloride; Electron Spin Resonance Spectroscopy; Guinea Pigs; Lipid Peroxidation; Male; Microsomes, Liver; NADP; Paraquat; Pentanes

1990
Microsomal metabolism of carbon tetrachloride: participation of pyridine nucleotide synergism.
    Biochemical medicine and metabolic biology, 1990, Volume: 44, Issue:1

    Topics: Animals; Carbon Tetrachloride; In Vitro Techniques; Lipid Peroxidation; Male; Microsomes, Liver; NAD; NADP; Phenobarbital; Pyridines; Rats; Rats, Inbred Strains

1990
Suicide inactivation of cytochrome P-450 by methoxsalen. Evidence for the covalent binding of a reactive intermediate to the protein moiety.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 250, Issue:3

    Topics: Animals; Carbon Monoxide; Carbon Tetrachloride; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Heme; Kinetics; Methoxsalen; Microsomes, Liver; Mixed Function Oxygenases; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Precipitin Tests; Protein Binding; Rats; Rats, Inbred Strains; Spectrum Analysis; Ultraviolet Rays

1989
Pentane as an index of in vitro lipid peroxidation via microsomal NADPH-P-450 enzyme systems.
    Hiroshima journal of medical sciences, 1989, Volume: 38, Issue:3

    Topics: Animals; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Guinea Pigs; In Vitro Techniques; Lipid Peroxidation; Male; Microsomes, Liver; NADP; Pentanes

1989
Dimethyldisulfide formation during trichloromethyl radical attack on methionine.
    Biochemical pharmacology, 1989, Nov-15, Volume: 38, Issue:22

    Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Disulfides; Gas Chromatography-Mass Spectrometry; Male; Methionine; Microsomes, Liver; NADP; Rats; Rats, Inbred Strains

1989
Chelating and free radical scavenging mechanisms of inhibitory action of rutin and quercetin in lipid peroxidation.
    Biochemical pharmacology, 1989, Jun-01, Volume: 38, Issue:11

    Topics: Aminopyrine N-Demethylase; Animals; Carbon Tetrachloride; Chelating Agents; Chemical Phenomena; Chemistry; Flavonoids; Free Radicals; Lipid Peroxides; Microsomes, Liver; NADP; Phosphatidylcholines; Quercetin; Rats; Rutin

1989
In vivo effects of immunostimulating lipopeptides on mouse liver microsomal cytochromes P-450 and on paracetamol-induced toxicity.
    Experientia, 1989, Sep-15, Volume: 45, Issue:9

    Topics: Acetaminophen; Adjuvants, Immunologic; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome b Group; Cytochrome P-450 Enzyme System; Cytochromes b5; Female; Lipid Peroxidation; Liver Diseases; Mice; Microsomes, Liver; NADP; Oligopeptides; Pimelic Acids

1989
Loss of latent activity of liver microsomal membrane enzymes evoked by lipid peroxidation. Studies of nucleoside diphosphatase, glucose-6-phosphatase, and UDP glucuronyltransferase.
    Biochimica et biophysica acta, 1985, Apr-26, Volume: 815, Issue:1

    Topics: Acid Anhydride Hydrolases; Animals; Carbon Tetrachloride; Ferric Compounds; Glucose-6-Phosphatase; Glucuronosyltransferase; Intracellular Membranes; Kinetics; Lipid Peroxides; Male; Microsomes, Liver; NADP; Phosphoric Monoester Hydrolases; Rats; Rats, Inbred Strains

1985
Radical activation of carbon tetrachloride in foetal and maternal rat liver microsomes.
    Biochemical pharmacology, 1986, Jun-15, Volume: 35, Issue:12

    Topics: Animals; Biotransformation; Calcium; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Female; Fetus; Free Radicals; In Vitro Techniques; Lipid Peroxides; Microsomes, Liver; NADP; Pregnancy; Rats; Rats, Inbred Strains

1986
Sodium cholate extraction of rat liver nuclear xenobiotic-metabolizing enzymes.
    Biochemical pharmacology, 1988, Apr-01, Volume: 37, Issue:7

    Topics: Animals; Carbon Tetrachloride; Cell Nucleus; Cholic Acid; Cholic Acids; Cytochrome P-450 Enzyme System; Cytosol; Liver; Male; Methylcholanthrene; NAD(P)H Dehydrogenase (Quinone); NADP; NADPH-Ferrihemoprotein Reductase; Pharmaceutical Preparations; Phenobarbital; Propane; Quinone Reductases; Rats; Rats, Inbred Strains

1988
The influence of CCl4 biotransformation on the activation of rat liver phospholipase C in vitro.
    Toxicology and applied pharmacology, 1988, Sep-15, Volume: 95, Issue:2

    Topics: Animals; Biotransformation; Calcium; Carbon Tetrachloride; Enzyme Activation; Liver; Male; Metyrapone; NADP; Pyridines; Rats; Rats, Inbred Strains; Type C Phospholipases

1988
Interaction of carbon tetrachloride and progesterone metabolism in liver microsomes from triacetyloleandomycin-treated rats.
    Archives of toxicology, 1987, Volume: 60, Issue:1-3

    Topics: Animals; Carbon Tetrachloride; Electrophoresis, Polyacrylamide Gel; In Vitro Techniques; Male; Microsomes, Liver; NADP; Progesterone; Rats; Rats, Inbred Strains; Troleandomycin

1987
NADPH-dependent and -independent loss of cytochrome P-450 in control and phenobarbital-induced rat hepatic microsomes incubated with carbon tetrachloride.
    Experimental and molecular pathology, 1986, Volume: 44, Issue:3

    Topics: Animals; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Male; Microsomes, Liver; NADP; Phenobarbital; Rats; Rats, Inbred Strains

1986
Distinct temporal relation among oxygen uptake, malondialdehyde formation, and low-level chemiluminescence during microsomal lipid peroxidation.
    Archives of biochemistry and biophysics, 1987, Volume: 252, Issue:1

    Topics: Adenosine Diphosphate; Animals; Carbon Tetrachloride; Iron; Kinetics; Lipid Peroxides; Luminescent Measurements; Male; Malonates; Malondialdehyde; Microsomes, Liver; NADP; Oxygen Consumption; Rats; Rats, Inbred Strains

1987
Inhibition of hepatic aldehyde dehydrogenase by carbon tetrachloride: an in vitro study.
    The International journal of biochemistry, 1985, Volume: 17, Issue:5

    Topics: Aldehyde Dehydrogenase; Animals; Carbon Tetrachloride; Edetic Acid; In Vitro Techniques; Liver; Male; Microsomes, Liver; Mitochondria, Liver; NAD; NADP; Rats; Rats, Inbred Strains; Time Factors

1985
Binding of 14 C-carbon tetrachloride to microsomal proteins in vitro and formation of CHC1 3 by reduced liver microsomes.
    Xenobiotica; the fate of foreign compounds in biological systems, 1973, Volume: 3, Issue:1

    Topics: Anaerobiosis; Animals; Carbon Isotopes; Carbon Monoxide; Carbon Tetrachloride; Chlorofluorocarbons, Methane; Chloroform; Cystamine; Cytochrome P-450 Enzyme System; Edetic Acid; Ethylmaleimide; Gallic Acid; Glutathione; In Vitro Techniques; Kinetics; Metyrapone; Microsomes, Liver; NADP; Oxidation-Reduction; Protein Binding; Proteins; Rabbits; Spectrophotometry

1973
Metabolic activation of halothane and its covalent binding to liver endoplasmic proteins in vitro.
    Naunyn-Schmiedeberg's archives of pharmacology, 1973, Volume: 279, Issue:1

    Topics: Anaerobiosis; Animals; Carbon Monoxide; Carbon Radioisotopes; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Glutathione; Halothane; In Vitro Techniques; Kidney; Lung; Metyrapone; Microsomes; Microsomes, Liver; NADP; Oxidation-Reduction; Oxygen; Proadifen; Protein Binding; Rabbits; Spectrophotometry; Sulfites

1973
The stimulation of lipid peroxidation produced by dimethylnitrosamine in rat liver microsomes in vitro: the effects of promethazine and inhibitors of drug metabolism, and a comparison with previous studies using carbon tetrachloride.
    Xenobiotica; the fate of foreign compounds in biological systems, 1973, Volume: 3, Issue:6

    Topics: Animals; Binding Sites; Carbon Tetrachloride; Chloromercuribenzoates; Cytochrome P-450 Enzyme System; Female; Kinetics; Lipid Metabolism; Male; Microsomes, Liver; NAD; NADP; Nitrosamines; Proadifen; Promethazine; Protein Binding; Rats; Spectrophotometry; Spectrophotometry, Ultraviolet; Stimulation, Chemical; Time Factors

1973
Increased carbon tetrachloride hepatotoxicity, and its mechanism, after chronic ethanol consumption.
    Gastroenterology, 1974, Volume: 66, Issue:3

    Topics: Alanine Transaminase; Alcohol Drinking; Aminopyrine N-Demethylase; Animals; Bilirubin; Biotransformation; Carbon Dioxide; Carbon Radioisotopes; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cytochrome P-450 Enzyme System; Drug Synergism; Ethanol; Female; Glucose-6-Phosphatase; In Vitro Techniques; Lipids; Liver; Microsomes, Liver; NADP; Ornithine Carbamoyltransferase; Protein Binding; Rats

1974
Effect of riboflavin and riboflavin 2',3',4',5'-tetrabutyrate on rat liver microsomal lipid peroxidation.
    Journal of nutritional science and vitaminology, 1974, Volume: 20, Issue:2

    Topics: Animals; Ascorbic Acid; Butyrates; Carbon Tetrachloride; Drug Synergism; Glucose-6-Phosphatase; Lipid Metabolism; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Oxygen Consumption; Peroxides; Rats; Riboflavin; Structure-Activity Relationship; Time Factors

1974
The protective effect of nicotinamide on carbon tetrachloride-induced hepatotoxicity.
    Biochemical pharmacology, 1967, Volume: 16, Issue:10

    Topics: Animals; Antidotes; Body Temperature; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Female; Liver; Mitochondria, Liver; NAD; NADP; Niacinamide; Rats; Temperature

1967
[Influence of diethylnitrosamine, carbon tetrachloride, butter yellow and cyclophosphamide on amino acid incorporation into fractions of liver homogenates after metabolic activation in vitro. Possibilities for the detection of hepatotoxic effects].
    Archiv fur Toxikologie, 1969, Volume: 25, Issue:2

    Topics: Amino Acids; Aniline Compounds; Animals; Carbon Isotopes; Carbon Tetrachloride; Cyclophosphamide; Leucine; Liver; Male; Microsomes; Models, Biological; NADP; Nitrosamines; p-Dimethylaminoazobenzene; Phenobarbital; Protein Biosynthesis; Rats

1969
Lipid peroxide formation in microsomes. Relationship of hydroxylation to lipid peroxide formation.
    The Biochemical journal, 1969, Volume: 113, Issue:2

    Topics: Aminopyrine; Animals; Carbon Tetrachloride; Chloroform; Chloromercuribenzoates; Codeine; Cysteine; Ethylmaleimide; Glutathione; In Vitro Techniques; Lipid Metabolism; Microsomes; NAD; NADP; Oxidation-Reduction; Peroxides; Rats

1969
Significance of mixed oxygenases and nitroreductase in drug metabolism.
    Annals of the New York Academy of Sciences, 1969, Oct-06, Volume: 160, Issue:2

    Topics: Animals; Anthelmintics; Carbon Monoxide; Carbon Tetrachloride; Chemical Phenomena; Chemistry; Cytochromes; Haplorhini; Imidazoles; Microsomes, Liver; NADP; Nitrogen; Oxidation-Reduction; Oxidoreductases; Oxygenases; Pharmaceutical Preparations; Phenobarbital

1969
Biochemical basis for the in vitro pro-oxidant action of carbon tetrachloride.
    Experimental and molecular pathology, 1969, Volume: 11, Issue:2

    Topics: Aldehydes; Animals; Antimetabolites; Benzene; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cytochromes; Edetic Acid; Electron Transport; Ferricyanides; Glutathione; Lipid Metabolism; Male; Malonates; Methane; Microsomes, Liver; NADP; Oxidation-Reduction; Rats

1969
[N-Hydroxylation of p-phenetidine in vivo and by isolated microsomes from liver and kidney: stimulation by phenobarbital pretreatment].
    Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1969, Volume: 264, Issue:4

    Topics: Aniline Compounds; Animals; Biotransformation; Carbon Tetrachloride; Chromatography, Thin Layer; Dogs; Kidney; Methemoglobin; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; NADP; Nitroso Compounds; Stimulation, Chemical; Ultraviolet Rays

1969
The effects of carbon tetrachloride and some antioxidants on the hydroxylation of tetralin by rat liver homogenate.
    Biochimica et biophysica acta, 1969, Oct-07, Volume: 192, Issue:1

    Topics: Alcohols; Aniline Compounds; Animals; Antioxidants; Carbon Tetrachloride; Chromatography, Gas; Depression, Chemical; Free Radicals; Glucosephosphate Dehydrogenase; Hexosephosphates; In Vitro Techniques; Liver; Microsomes, Liver; NADP; Naphthalenes; Perfusion; Peroxides; Rats; Stimulation, Chemical; Vitamin E

1969
A comparison of the effects of halothane and CCl 4 on the hepatic drug metabolizing system.
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 177, Issue:3

    Topics: Aniline Compounds; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cytochromes; Dealkylation; Halothane; Liver; Male; Microscopy, Electron; Microsomes, Liver; Mixed Function Oxygenases; Morphinans; NADP; Organ Size; Oxidoreductases; Phenobarbital; Rats

1971
Drug metabolism in man: past, present, and future.
    Annals of the New York Academy of Sciences, 1971, Jul-06, Volume: 179

    Topics: Aerobiosis; Alkylating Agents; Allyl Compounds; Animals; Autoradiography; Bromine; Carbon Isotopes; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemistry; Chlorine; Chromatography, Paper; Ethers, Cyclic; Glutathione; Hydrocarbons, Halogenated; Iodine; Liver; Male; Mice; Microsomes, Liver; Models, Biological; NADP; Necrosis; Phenobarbital; Rats; Sheep; Sulfur Isotopes

1971
Effect of carbon tetrachloride induced progressive liver damage on drug-metabolizing enzymes and cytochrome P-450 in rat liver.
    Acta pharmacologica et toxicologica, 1971, Volume: 29, Issue:5

    Topics: Aniline Compounds; Animals; Body Weight; Carbon Tetrachloride; Cytochromes; Glucosephosphate Dehydrogenase; Hexobarbital; Liver; Liver Cirrhosis; NADP; Nitrophenols; Oxidoreductases; Rats; Time Factors

1971
The stimulatory effects of carbon tetrachloride and other halogenoalkanes on peroxidative reactions in rat liver fractions in vitro. General features of the systems used.
    The Biochemical journal, 1971, Volume: 123, Issue:5

    Topics: Aldehydes; Animals; Carbon Tetrachloride; Chloroform; Female; Free Radicals; Glucose-6-Phosphatase; Hydrocarbons, Halogenated; In Vitro Techniques; Lipid Metabolism; Liver; Malonates; Microsomes, Liver; NADP; Peroxides; Rats

1971
The stimulatory effects of carbon tetrachloride on peroxidative reactions in rat liver fractions in vitro. Interaction sites in the endoplasmic reticulum.
    The Biochemical journal, 1971, Volume: 123, Issue:5

    Topics: Aldehydes; Aminopyrine; Animals; Carbon Monoxide; Carbon Tetrachloride; Chloromercuribenzoates; Cytochromes; Electron Transport; Endoplasmic Reticulum; In Vitro Techniques; Lipid Metabolism; Liver; Malonates; Microsomes, Liver; NADP; Niacinamide; Peroxides; Proadifen; Rats

1971
Inhibition of NADPH-cytochrome c reductase by propyl gallate.
    Biochemical pharmacology, 1971, Volume: 20, Issue:8

    Topics: Aminopyrine; Animals; Antioxidants; Benzoates; Carbon Tetrachloride; Cresols; Dealkylation; Electron Transport; Female; Free Radicals; In Vitro Techniques; Microsomes, Liver; NADP; Oxidoreductases; Oxygen Consumption; Rats; Spectrophotometry

1971
[Extraction of cytochrome P450 after incubation with CCl 4 in an NADPH-regenerating system and partial transformation into cytochrome P420].
    Experientia, 1971, Volume: 27, Issue:7

    Topics: Animals; Carbon Tetrachloride; Cytochromes; Drug Interactions; Male; Microsomes; NADP; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred Strains

1971
Incorporation of radioactive- -aminolevulinic acid into microsomal cytochrome P 450 : selective breakdown of the hemoprotein by allylisopropylacetamide and carbon tetrachloride.
    Archives of biochemistry and biophysics, 1972, Volume: 148, Issue:1

    Topics: Acetamides; Allyl Compounds; Amides; Amino Acids; Animals; Carbon Monoxide; Carbon Tetrachloride; Cytochromes; Heme; Kinetics; Levulinic Acids; Male; Microsomes, Liver; NADP; Oxidoreductases; Protein Binding; Proteins; Rats; Spectrophotometry; Tritium

1972
[Effect of experimental liver damage on the reduction of testosterone and 4-androstene-3,17-dione].
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1972, Volume: 157, Issue:2

    Topics: 17-Ketosteroids; Androstanes; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Ethanol; In Vitro Techniques; Liver Diseases; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Rats; Rats, Inbred Strains; Testosterone

1972
A comparison of mouse and rat liver enzymes and their response to treatment with various compounds.
    Biochemical pharmacology, 1972, Apr-01, Volume: 21, Issue:7

    Topics: Aminopyrine; Animals; Carbon Tetrachloride; Chlorpromazine; Clofibrate; Cytochromes; DDT; Germ-Free Life; Glucose-6-Phosphatase; Glucosephosphate Dehydrogenase; Griseofulvin; L-Lactate Dehydrogenase; Liver; Mice; NAD; NADP; Organ Size; Oxidoreductases; Phenobarbital; Phosphogluconate Dehydrogenase; Rats; Species Specificity

1972
Hepatic microsomal ethanol oxidation. Mechanism and physiologic significance.
    Laboratory investigation; a journal of technical methods and pathology, 1972, Volume: 27, Issue:3

    Topics: Animals; Carbon Dioxide; Carbon Isotopes; Carbon Tetrachloride; Catalase; Culture Techniques; Cyanides; Diet; Ethanol; Female; Hydrogen Peroxide; Microsomes, Liver; NADP; Rats; Triazoles

1972
Effect of ethylene dibromide and carbon tetrachloride on lipid peroxidation in rat and chick liver.
    Experimental and molecular pathology, 1972, Volume: 17, Issue:2

    Topics: Aldehydes; Analysis of Variance; Animals; Carbon Tetrachloride; Cell-Free System; Chickens; Glutathione; Hydrocarbons, Halogenated; In Vitro Techniques; Lipid Metabolism; Liver; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Rats

1972
[Formation of chloroform from carbon tetrachloride in liver microsomes, lipid peroxidation and destruction of cytochrome P-450].
    Archiv fur Toxikologie, 1972, Volume: 29, Issue:3

    Topics: Alcohols; Animals; Carbon Monoxide; Carbon Tetrachloride; Chloroform; Cytochrome P-450 Enzyme System; Desipramine; Disulfiram; Flavonoids; Linoleic Acids; Lipid Metabolism; Male; Metyrapone; Microsomes, Liver; NADP; Oxidation-Reduction; Oxygen; Oxygenases; Piperonyl Butoxide; Rabbits; Rats; Ultraviolet Rays

1972
Enhanced hepatic microsomal activity by pretreatment of rats with acetone or isopropanol.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1973, Volume: 142, Issue:1

    Topics: 1-Propanol; Acetone; Animals; Carbon Isotopes; Carbon Tetrachloride; Chloroform; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Male; Microsomes, Liver; Morphine; NAD; NADP; Nitrosamines; Protein Binding; Rats

1973
Carbon tetrachloride-induced protection against carbon tetrachloride toxicity. The role of the liver microsomal drug-metabolizing system.
    Biochemical pharmacology, 1972, Jun-15, Volume: 21, Issue:12

    Topics: Aminopyrine N-Demethylase; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cytochrome c Group; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Drug Resistance; Male; Microsomes, Liver; NADP; Proteins; Rats; Time Factors

1972
Studies on an unusual N-dealkylation reaction. II. Characteristics of the enzyme system and a proposed pathway for the reaction.
    The Journal of pharmacology and experimental therapeutics, 1973, Volume: 184, Issue:3

    Topics: Anaerobiosis; Animals; Butanes; Carbon Tetrachloride; Cytoplasm; Decarboxylation; Histamine H1 Antagonists; Hydroxylation; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; NAD; NADP; Oxidation-Reduction; Oxides; Oxygen; Phenobarbital; Piperazines; Rats; Subcellular Fractions

1973
Carbon tetrachloride activation by highly purified liver mitochondrial preparations.
    Agents and actions, 1984, Volume: 15, Issue:5-6

    Topics: Animals; Biotransformation; Carbon Tetrachloride; Cyanides; Glucose-6-Phosphatase; In Vitro Techniques; Male; Microscopy, Electron; Microsomes, Liver; Mitochondria, Liver; NADP; Phenobarbital; Rats; Rats, Inbred Strains

1984
Confirmation of assignment of the trichloromethyl radical spin adduct detected by spin trapping during 13C-carbon tetrachloride metabolism in vitro and in vivo.
    Biochemical and biophysical research communications, 1980, Jun-30, Volume: 94, Issue:4

    Topics: Animals; Carbon Isotopes; Carbon Tetrachloride; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrocarbons, Chlorinated; Male; Microsomes, Liver; NADP; Nitrogen Oxides; Rats

1980
A comparison of NADPH and cumene hydroperoxide-stimulated lipid peroxidation in mouse hepatic microsomes.
    The International journal of biochemistry, 1981, Volume: 13, Issue:7

    Topics: Animals; Benzene Derivatives; Carbon Tetrachloride; Diphosphates; Dithiothreitol; Edetic Acid; Iron; Lipid Peroxides; Male; Mice; Microsomes, Liver; NADP; Paraquat; Peroxides

1981
An update on antioxidant theory: spin trapping of trichloromethyl radicals in vivo.
    Annals of the New York Academy of Sciences, 1982, Volume: 393

    Topics: Animals; Antioxidants; Carbon Tetrachloride; Electron Spin Resonance Spectroscopy; Microsomes, Liver; NADP; Oxidation-Reduction; Rats; Vitamin E

1982
Ethanol-inducible cytochrome P-450 is more susceptible to in vitro carbon tetrachloride-mediated destruction than phenobarbital-inducible and beta-naphthoflavone-inducible cytochromes P-450.
    Acta pharmacologica et toxicologica, 1984, Volume: 55, Issue:3

    Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Benzoflavones; beta-Naphthoflavone; Biotransformation; Carbon Tetrachloride; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Ethanol; Free Radicals; Male; Microsomes, Liver; NADP; Nitroanisole O-Demethylase; Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains

1984
Pretreatment with taurine facilitates hepatic lipid peroxide formation associated with carbon tetrachloride intoxication.
    Japanese journal of pharmacology, 1983, Volume: 33, Issue:3

    Topics: Animals; Calcium; Carbon Tetrachloride; Iron; Lipid Peroxides; Liver; Male; Microsomes, Liver; NADP; Necrosis; Rats; Rats, Inbred Strains; Taurine

1983
Identification of dichloromethyl carbene as a metabolite of carbon tetrachloride.
    Biochemical and biophysical research communications, 1983, Dec-16, Volume: 117, Issue:2

    Topics: Alkenes; Animals; Carbon Monoxide; Carbon Tetrachloride; Cyclopropanes; Cytochrome P-450 Enzyme System; Gas Chromatography-Mass Spectrometry; Hydrocarbons, Chlorinated; Male; Microsomes, Liver; NADP; Rats; Rats, Inbred Strains

1983
Alkane formation during liver microsomal lipid peroxidation.
    Biochemical pharmacology, 1982, Feb-15, Volume: 31, Issue:4

    Topics: Alkanes; Animals; Carbon Tetrachloride; In Vitro Techniques; Lipid Peroxides; Microsomes, Liver; NADP; Rats

1982
Carbon tetrachloride-induced lipid peroxidation: a spin trapping study.
    Toxicology letters, 1982, Volume: 10, Issue:4

    Topics: Animals; Carbon Tetrachloride; Free Radicals; In Vitro Techniques; Lipid Peroxides; Male; Microsomes, Liver; NADP; Rats; Rats, Inbred F344; Spin Labels

1982
Pharmacological properties of Dibenzo[a,c]cyclooctene derivatives isolated from Fructus Schizandrae Chinensis III. Inhibitory effects on carbon tetrachloride-induced lipid peroxidation, metabolism and covalent binding of carbon tetrachloride to lipids.
    Chemico-biological interactions, 1982, Jul-15, Volume: 41, Issue:1

    Topics: Animals; Carbon Tetrachloride; China; Cyclooctanes; Dioxoles; Lignans; Lipid Metabolism; Lipid Peroxides; Male; Mice; Mice, Inbred DBA; Microsomes, Liver; NADP; Oxygen Consumption; Plants, Medicinal; Polycyclic Compounds

1982
1, 1-Dichloroethylene inhibition of liver microsomal calcium pump in vitro.
    Archives of biochemistry and biophysics, 1982, Oct-01, Volume: 218, Issue:1

    Topics: Animals; Biological Transport, Active; Calcium; Carbon Tetrachloride; Dichloroethylenes; Endoplasmic Reticulum; Hydrocarbons, Chlorinated; Male; Microsomes, Liver; NADP; Rats; Rats, Inbred Strains

1982
The influence of carbon tetrachloride metabolism on the carbon tetrachloride-induced activation of rat liver cell phospholipase C activity.
    Toxicology and applied pharmacology, 1982, Sep-30, Volume: 65, Issue:3

    Topics: Animals; Carbon Monoxide; Carbon Tetrachloride; Cell Membrane; Enzyme Activation; Glycerophosphates; Liver; Male; NADP; Phosphatidylcholines; Phospholipases; Protein Binding; Rats; Rats, Inbred Strains; Type C Phospholipases

1982
Self-catalysed, O2-independent inactivation of NADPH- or dithionite-reduced microsomal cytochrome P-450 by carbon tetrachloride.
    Biochemical pharmacology, 1981, Aug-15, Volume: 30, Issue:16

    Topics: Anaerobiosis; Animals; Carbon Monoxide; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Dithionite; Female; In Vitro Techniques; Microsomes, Liver; NADP; Oxidation-Reduction; Oxygen; Rats; Rats, Inbred Strains; Sulfites

1981
Inhibition of rat liver aldehyde dehydrogenase by carbon tetrachloride.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 219, Issue:3

    Topics: Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; Animals; Body Weight; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Lipid Peroxides; Liver; Male; NADP; Organ Size; Rats; Rats, Inbred Strains; Subcellular Fractions

1981
Covalent binding of CCl4-intermediates to reduced pyridine nucleotides in mouse liver.
    Advances in experimental medicine and biology, 1981, Volume: 136 Pt A

    Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cell Nucleus; Chromatography, Ion Exchange; Liver; Mice; Microsomes, Liver; NAD; NADP; Oxidation-Reduction; RNA, Ribosomal; RNA, Transfer

1981
Nuclear activation of carbon tetrachloride and chloroform.
    Research communications in chemical pathology and pharmacology, 1980, Volume: 27, Issue:1

    Topics: Aerobiosis; Anaerobiosis; Animals; Biotransformation; Carbon Tetrachloride; Cell Nucleus; Chloroform; In Vitro Techniques; Liver; Male; NADP; Rats

1980
The mechanism of chloroform and carbon monoxide formation from carbon tetrachloride by microsomal cytochrome P-450.
    Biochemical pharmacology, 1980, Oct-15, Volume: 29, Issue:20

    Topics: Anaerobiosis; Animals; Carbon Monoxide; Carbon Tetrachloride; Chloroform; Cytochrome P-450 Enzyme System; Male; Microsomes, Liver; NADP; Protoporphyrins; Rats

1980
Metabolism of carbon tetrachloride in hepatic microsomes and reconstituted monooxygenase systems and its relationship to lipid peroxidation.
    Molecular pharmacology, 1980, Volume: 18, Issue:3

    Topics: Animals; Carbon Tetrachloride; Free Radicals; Lipid Peroxides; Male; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidoreductases; Oxygen Consumption; Rabbits

1980
Dithiothreitol inhibitory effects on carbon tetrachloride-promoted NADPH-dependent lipid peroxidation in liver microsomal suspensions.
    Research communications in molecular pathology and pharmacology, 1995, Volume: 88, Issue:2

    Topics: Animals; Carbon Tetrachloride; Dithiothreitol; Free Radicals; Lipid Peroxidation; Male; Microsomes, Liver; NADP; Rats; Rats, Sprague-Dawley

1995
Study of reproducibility of spin trapping results in the use of C-phenyl-N-tert-butyl nitrone (PBN) for trichloromethyl radical detection in CCl4 metabolism by rat liver microsomal dispersions. Biological spin trapping I.
    Journal of biochemical and biophysical methods, 1994, Volume: 29, Issue:3-4

    Topics: Animals; Carbon Isotopes; Carbon Tetrachloride; Catalase; Cyclic N-Oxides; Dimethyl Sulfoxide; Electron Spin Resonance Spectroscopy; Kinetics; Male; Microsomes, Liver; NADP; Nitrogen Oxides; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Solubility; Spin Labels

1994
Further evidence for zinc as a hepatoprotective agent in rat liver toxicity.
    Experimental and molecular pathology, 1995, Volume: 63, Issue:2

    Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Glutathione; Lipid Peroxidation; Liver; Liver Diseases; Male; Mixed Function Oxygenases; NADP; Rats; Zinc

1995
The crucial antioxidant action of schisandrin B in protecting against carbon tetrachloride hepatotoxicity in mice: a comparative study with butylated hydroxytoluene.
    Biochemical pharmacology, 1996, Dec-13, Volume: 52, Issue:11

    Topics: Alanine Transaminase; Animals; Antioxidants; Butylated Hydroxytoluene; Carbon Tetrachloride; Cyclooctanes; Female; Lignans; Liver; Mice; Mice, Inbred BALB C; NADP; Polycyclic Compounds

1996
Antioxidative effect of sesamol and related compounds on lipid peroxidation.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:4

    Topics: Animals; Antioxidants; Ascorbic Acid; Benzodioxoles; Carbon Tetrachloride; Eugenol; Ferrous Compounds; Lipid Peroxidation; Liposomes; Liver; Male; Malondialdehyde; Microsomes, Liver; Mitochondria, Liver; NADP; Oxidation-Reduction; Phenols; Rats; Rats, Wistar; Structure-Activity Relationship

1996
Protection of rat liver microsomes against carbon tetrachloride-induced lipid peroxidation by red ginseng saponin through cytochrome P450 inhibition.
    Planta medica, 1997, Volume: 63, Issue:5

    Topics: Animals; Carbon Tetrachloride; Cytochrome P-450 CYP2E1 Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Kinetics; Lipid Peroxidation; Male; Microsomes, Liver; NADP; Panax; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Saponins

1997
Clarification of the relationship between free radical spin trapping and carbon tetrachloride metabolism in microsomal systems.
    Free radical biology & medicine, 1998, Volume: 24, Issue:9

    Topics: Animals; Carbon Dioxide; Carbon Tetrachloride; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Glutathione; Male; Microsomes, Liver; NADP; Nitrogen Oxides; Rats; Rats, Sprague-Dawley; Spin Labels; Spin Trapping

1998
Xenobiotic-metabolizing enzymes in pig nasal and hepatic tissues.
    Xenobiotica; the fate of foreign compounds in biological systems, 1998, Volume: 28, Issue:10

    Topics: Animals; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Enzymes; Epoxide Hydrolases; Esterases; Female; Glucuronosyltransferase; Lipid Peroxidation; Liver; Microsomes; Microsomes, Liver; NADP; Nasal Mucosa; Olfactory Mucosa; Swine; Testosterone; Xenobiotics

1998
The roles played by crucial free radicals like lipid free radicals, nitric oxide, and enzymes NOS and NADPH in CCl(4)-induced acute liver injury of mice.
    Free radical biology & medicine, 2000, Nov-01, Volume: 29, Issue:9

    Topics: Alanine Transaminase; Animals; Arginine; Carbon Tetrachloride; Free Radicals; L-Lactate Dehydrogenase; Lipid Metabolism; Liver; Male; Mice; Mice, Inbred ICR; NADP; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroprusside; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances

2000
Cytochrome P450 2E1 dependent catalytic activity and lipid peroxidation in rat blood lymphocytes.
    Life sciences, 2002, Oct-11, Volume: 71, Issue:21

    Topics: Acetone; Animals; Antibodies, Blocking; Carbon Tetrachloride; Cytochrome P-450 CYP2E1; Enzyme Inhibitors; Ethanol; Isoenzymes; Lipid Peroxidation; Lymphocytes; Male; Microsomes, Liver; NADP; Pyrazoles; Rats; Rats, Wistar

2002
[The activity of DPNH- and TPNH-related microsomal enzymes in the carbon tetrachloride-damaged mouse liver].
    Acta biologica et medica Germanica, 1962, Volume: 9

    Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Dihydrolipoamide Dehydrogenase; Liver Diseases; Mice; NAD; NADP; Oxidoreductases

1962
THE CONVERSION OF CARBON TETRACHLORIDE AND CHLOROFORM TO CARBON DIOXIDE BY RAT LIVER HOMOGENATES.
    Canadian journal of biochemistry, 1964, Volume: 42

    Topics: Benzoates; Carbon Dioxide; Carbon Tetrachloride; Chloroform; Chloromercuribenzoates; Coenzymes; Glutathione; Liver; NAD; NADP; Oxidation-Reduction; Pharmacology; Research

1964
A NOTE ON THE RELATIVE TOXIC ACTIVITIES OF TETRACHLOROMETHANE AND TRICHLORO-FLUORO-METHANE ON THE RAT.
    Biochemical pharmacology, 1965, Volume: 14

    Topics: Blood; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemistry, Physical; Chloroform; Fluorides; Glucuronidase; Hepatitis; Methane; NADP; Necrosis; Rats; Research; Solvents; Toxicology

1965
Effect of purified saponin mixture from Astragalus corniculatus on enzyme- and non-enzyme-induced lipid peroxidation in liver microsomes from spontaneously hypertensive rats and normotensive rats.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2010, Volume: 17, Issue:5

    Topics: Animals; Antioxidants; Ascorbic Acid; Astragalus Plant; Carbon Tetrachloride; Disease Models, Animal; Iron Compounds; Lipid Peroxidation; Malondialdehyde; Microsomes, Liver; NADP; Oxidative Stress; Plant Extracts; Rats; Rats, Inbred SHR; Rats, Wistar; Saponins; Spectrophotometry

2010
Effect of functional groups on antioxidant properties of substituted selenoethers.
    Free radical research, 2011, Volume: 45, Issue:4

    Topics: Antioxidants; Carbon Tetrachloride; Chromatography, High Pressure Liquid; DNA Damage; Ethers; Free Radical Scavengers; Glutathione; Glutathione Peroxidase; Molecular Mimicry; NADP; Oxidation-Reduction; Plasmids; Pulse Radiolysis; Selenic Acid; Selenium; Selenium Compounds; Solutions

2011
NOX1/nicotinamide adenine dinucleotide phosphate, reduced form (NADPH) oxidase promotes proliferation of stellate cells and aggravates liver fibrosis induced by bile duct ligation.
    Hepatology (Baltimore, Md.), 2011, Sep-02, Volume: 54, Issue:3

    Topics: Animals; Carbon Tetrachloride; Cell Cycle Proteins; Cell Proliferation; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p27; Forkhead Transcription Factors; Hepatic Stellate Cells; Ligation; Liver Cirrhosis, Experimental; Mice; NADH, NADPH Oxidoreductases; NADP; NADPH Oxidase 1; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Reactive Oxygen Species; Signal Transduction

2011
Protective effect of bixin on carbon tetrachloride-induced hepatotoxicity in rats.
    Biological research, 2014, Sep-29, Volume: 47

    Topics: Animals; Antioxidants; Bixaceae; Carbon Tetrachloride; Carotenoids; Chemical and Drug Induced Liver Injury; Glutathione; Glutathione Reductase; Lipid Peroxidation; Liver; Male; Malondialdehyde; NADP; Oxidative Stress; Plant Extracts; Rats, Wistar; Reactive Oxygen Species; Transaminases

2014
Vitamin D3-induced hypercalcemia increases carbon tetrachloride-induced hepatotoxicity through elevated oxidative stress in mice.
    PloS one, 2017, Volume: 12, Issue:4

    Topics: Adenosine Triphosphate; Animals; Body Weight; Calcium; Carbon Tetrachloride; Cholecalciferol; Cytochrome P-450 CYP2E1; Hypercalcemia; Lipid Peroxidation; Liver; Male; Malondialdehyde; Mice; NADP; Oxidative Stress

2017