carbon tetrachloride has been researched along with methoxsalen in 2 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beaune, P; Descatoire, V; Labbe, G; Larrey, D; Letteron, P; Pessayre, D | 1 |
| Amouyal, G; Carrion-Pavlov, Y; Degott, C; Descatoire, V; Geneve, J; Labbe, G; Larrey, D; Letteron, P; Pessayre, D; Tinel, M | 1 |
2 other study(ies) available for carbon tetrachloride and methoxsalen
| Article | Year |
|---|---|
Suicide inactivation of cytochrome P-450 by methoxsalen. Evidence for the covalent binding of a reactive intermediate to the protein moiety.
Topics: Animals; Carbon Monoxide; Carbon Tetrachloride; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Heme; Kinetics; Methoxsalen; Microsomes, Liver; Mixed Function Oxygenases; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Precipitin Tests; Protein Binding; Rats; Rats, Inbred Strains; Spectrum Analysis; Ultraviolet Rays | 1989 |
The drug methoxsalen, a suicide substrate for cytochrome P-450, decreases the metabolic activation, and prevents the hepatotoxicity, of carbon tetrachloride in mice.
Topics: Alanine Transaminase; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Lipid Peroxides; Liver Diseases; Male; Methoxsalen; Mice; Mice, Inbred ICR; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Necrosis | 1987 |