carbon tetrachloride has been researched along with methotrexate in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (42.86) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 6 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Schaffner, F | 1 |
| Riely, CA | 1 |
| Lin, S; Saito, H; Shiga, J; Yohro, T | 1 |
| Roschlau, G | 1 |
| Yoshino, T | 1 |
| Mørland, J; Vonen, B | 1 |
| Allen, RL; Billington, D; Osypiw, JC | 1 |
| Chan, ES; Chen, JF; Cronstein, BN; Delano, DL; Desai, A; Fernandez, P; Friedman, SL; Montesinos, MC; Pillinger, MH; Reiss, AB; Schwarzschild, MA; Yee, H | 1 |
| Chung, BC; Jung, BH; Kumar, BS; Kwon, OS | 1 |
1 review(s) available for carbon tetrachloride and methotrexate
| Article | Year |
|---|---|
Hepatic drug metabolism and adverse hepatic drug reactions.
Topics: Adaptation, Biological; Animals; Biotransformation; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cholestasis; Chronic Disease; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Endoplasmic Reticulum; Enzyme Induction; Free Radicals; Glucose-6-Phosphatase; Halothane; Humans; Liver; Methotrexate; Microsomes, Liver; Oxyphenisatin Acetate; Rats; Vinyl Chloride | 1975 |
13 other study(ies) available for carbon tetrachloride and methotrexate
| Article | Year |
|---|---|
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Drugs and what they do to the liver.
Topics: Adrenal Cortex Hormones; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Humans; Liver; Methotrexate; Pyrrolizidine Alkaloids; Tetracycline; Vitamin A | 1978 |
Acute hepatotoxicity induced by hepatotoxins in Suncus murinus.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Ethanol; Galactosamine; Gallbladder; Liver; Male; Methotrexate; Mice; Rats; Rats, Inbred Strains; Shrews; Species Specificity | 1986 |
[Possibilities of protraction of murine viral hepatitis. An experimental study].
Topics: Amyloidosis; Animals; Carbon Tetrachloride; Chronic Disease; Female; Freund's Adjuvant; Hepatitis, Animal; Male; Methotrexate; Mice; Mice, Inbred Strains; Murine hepatitis virus; Spleen; Splenectomy; Virulence | 1972 |
The clinical and experimental studies on the metabolism of folic acid using tritiated folic acid. 3. Plasma clearance in man and organ distribution in rat following intravenous administration of tritiated folic acid.
Topics: Acute Disease; Animals; Body Weight; Bone Marrow; Carbon Tetrachloride; Chronic Disease; Folic Acid; Hematologic Diseases; Humans; Injections, Intravenous; Kidney; Leukemia; Liver; Liver Diseases; Methotrexate; Rats; Spleen; Tritium | 1968 |
Isolated rat hepatocytes in suspension: potential hepatotoxic effects of six different drugs.
Topics: Acetaminophen; Adenosine Triphosphate; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Cell Survival; Chemical and Drug Induced Liver Injury; Ethanol; Fentanyl; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Methotrexate; Oxytetracycline; Protein Biosynthesis; Rats; Valine | 1984 |
Subpopulations of rat hepatocytes separated by Percoll density-gradient centrifugation show characteristics consistent with different acinar locations.
Topics: 1-Naphthylisothiocyanate; Acetaminophen; Alanine Transaminase; Animals; Carbon Tetrachloride; Cell Separation; Cell Survival; Cells, Cultured; Centrifugation, Density Gradient; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; L-Lactate Dehydrogenase; Liver; Malate Dehydrogenase; Male; Methotrexate; Pyruvate Kinase; Rats; Rats, Wistar | 1994 |
Adenosine A(2A) receptors play a role in the pathogenesis of hepatic cirrhosis.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Animals; Blotting, Western; Caffeine; Carbon Tetrachloride; Cell Line; Chromatography, High Pressure Liquid; Ethanol; Hepatocytes; Humans; Liver Cirrhosis; Matrix Metalloproteinases, Membrane-Associated; Methotrexate; Mice; Mice, Inbred C57BL; Rats; Receptor, Adenosine A2A; Reverse Transcriptase Polymerase Chain Reaction; Thioacetamide; Triazines; Triazoles | 2006 |
Discovery of common urinary biomarkers for hepatotoxicity induced by carbon tetrachloride, acetaminophen and methotrexate by mass spectrometry-based metabolomics.
Topics: Acetaminophen; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bile Acids and Salts; Biomarkers; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chromatography, Liquid; Discriminant Analysis; Liver; Male; Mass Spectrometry; Metabolome; Metabolomics; Methotrexate; Multivariate Analysis; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Steroids | 2012 |