Compounds > carbon tetrachloride
Page last updated: 2024-08-17

carbon tetrachloride and metformin

carbon tetrachloride has been researched along with metformin in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (77.78)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Dai, J; Fan, K; Ge, P; He, X; Hu, K; Lin, L; Wu, K; Zhang, L1
Callegari, E; Gramantieri, L; Guerriero, P; Negrini, M; Pinton, P; Rimessi, A; Sabbioni, S; Shankaraiah, RC; Silini, EM1
Abd El-Fattah, EE; Abd-Eldayem, MA; Abdelhamid, AM; Abou-Elrous, M; Amin, NA; El-Ahwany, E; Gaafar, AGA; Girgis, S; Gobba, NA; Hafez, AM; Saber, S; Shahien, MA; Shata, A; Youssef, ME1
Ahmed, AA; Ahmed, MA; El-Bakry, MH; Hasan, A; Omar, ZMM1

Other Studies

9 other study(ies) available for carbon tetrachloride and metformin

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Metformin mitigates carbon tetrachloride-induced TGF-β1/Smad3 signaling and liver fibrosis in mice.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 90

    Topics: Actins; Animals; Antioxidants; Carbon Tetrachloride; Collagen Type I; Heme Oxygenase-1; Hepatic Stellate Cells; Liver; Liver Cirrhosis; Male; Metformin; Mice; Mice, Inbred BALB C; NAD(P)H Dehydrogenase (Quinone); Phosphorylation; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta1; Up-Regulation

2017
Metformin prevents liver tumourigenesis by attenuating fibrosis in a transgenic mouse model of hepatocellular carcinoma.
    Oncogene, 2019, Volume: 38, Issue:45

    Topics: Animals; Carbon Tetrachloride; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Disease Models, Animal; Fibrosis; Humans; Hypoglycemic Agents; Liver Neoplasms, Experimental; Male; Metformin; Mice; Mice, Transgenic; MicroRNAs

2019
Blunting p38 MAPKα and ERK1/2 activities by empagliflozin enhances the antifibrotic effect of metformin and augments its AMPK-induced NF-κB inactivation in mice intoxicated with carbon tetrachloride.
    Life sciences, 2021, Dec-01, Volume: 286

    Topics: Adenylate Kinase; AMP-Activated Protein Kinases; Animals; Benzhydryl Compounds; Carbon Tetrachloride; Drug Therapy, Combination; Female; Glucosides; Hepatocytes; Liver; Liver Cirrhosis; Male; MAP Kinase Signaling System; Metformin; Mice; Mice, Inbred BALB C; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Primary Cell Culture; Signal Transduction; Transcription Factor RelA

2021
Metformin versus silymarin as hepatoprotective agents in mice fibrotic model caused by carbon tetrachloride.
    Annales pharmaceutiques francaises, 2022, Volume: 80, Issue:5

    Topics: Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Liver; Liver Cirrhosis; Metformin; Mice; Oxidative Stress; Silymarin

2022