carbon tetrachloride has been researched along with metallothionein in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (13.64) | 18.7374 |
| 1990's | 9 (40.91) | 18.2507 |
| 2000's | 4 (18.18) | 29.6817 |
| 2010's | 6 (27.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cagen, SZ; Klaassen, CD | 1 |
| Etienne, AT; Webb, M | 1 |
| Min, KS; Onosaka, S; Tanaka, K; Terano, Y | 1 |
| Lui, EM; Suntres, ZE | 1 |
| Cousins, RJ; Schroeder, JJ | 1 |
| Min, K; Nomura, H; Onosaka, S; Tanaka, K | 1 |
| Hojo, H; Sasaki, M; Sato, M | 1 |
| Carlson, GP; DiSilvestro, RA | 1 |
| Itoh, N; Kimura, T; Kitagawa, I; Kobayashi, M; Muto, N; Nakanishi, H; Tanaka, K | 1 |
| Klaassen, CD; Liu, J | 1 |
| Hartley, DP; Liu, J; Liu, Y | 1 |
| Cabré, M; Camps, J; del Castillo, D; Ferré, N; Folch, J; Hernàndez, M; Joven, J; Paternain, JL | 1 |
| Kanelli, H; Koutselinis, AS; Margeli, AP; Spiliopoulou, CA; Theocharis, SE | 1 |
| Cousins, RJ; Davis, SR; Samuelson, DA | 1 |
| Cabré, M; Camps, J; Ferré, N; Joven, J; Paternáin, JL | 1 |
| Jiang, Y; Kang, YJ | 1 |
| Domitrović, R; Jakovac, H | 1 |
| Kaneko, M; Mori, M; Nagamine, T; Nakazato, K | 1 |
| Cheng, M; Jiang, H; Nie, F; Wang, Y; Zhang, B | 1 |
| Nonogaki, T; Onosaka, S; Usuda, H; Yoshioka, H | 1 |
| Fukuishi, N; Nonogaki, T; Onosaka, S; Usuda, H; Yoshioka, H | 1 |
| Fukaya, S; Miura, N; Nagatsu, A; Nonogaki, T; Onosaka, S; Yoshioka, H | 1 |
1 review(s) available for carbon tetrachloride and metallothionein
| Article | Year |
|---|---|
Induction of metallothionein as an adaptive mechanism affecting the magnitude and progression of toxicological injury.
Topics: Adaptation, Physiological; Animals; Cadmium; Carbon Tetrachloride; Liver; Metallothionein; Mice; Rats | 1998 |
21 other study(ies) available for carbon tetrachloride and metallothionein
| Article | Year |
|---|---|
Protection of carbon tetrachloride-induced hepatotoxicity by zinc: role of metallothionein.
Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Cytosol; Lipid Metabolism; Male; Metalloproteins; Metallothionein; Microsomes, Liver; Rats; Time Factors; Zinc | 1979 |
Studies on the toxicity and metabolism of cadmium-thionein.
Topics: Animals; Cadmium; Carbon Tetrachloride; Female; In Vitro Techniques; Kidney Cortex; Lethal Dose 50; Liver; Metalloproteins; Metallothionein; Plants, Toxic; Pyrrolizidine Alkaloids; Rabbits; Rats; Senecio; Time Factors | 1977 |
Induction of metallothionein synthesis by menadione or carbon tetrachloride is independent of free radical production.
Topics: Animals; Carbon Tetrachloride; Free Radicals; Lipid Peroxidation; Liver; Male; Metallothionein; Mice; Phenobarbital; Vitamin E; Vitamin K | 1992 |
Biochemical mechanism of metallothionein--carbon tetrachloride interaction in vitro.
Topics: Animals; Binding Sites; Cadmium; Carbon Radioisotopes; Carbon Tetrachloride; Dithiothreitol; Drug Interactions; Male; Metallothionein; Microsomes, Liver; Rats; Rats, Inbred Strains; Zinc | 1990 |
Interleukin 6 regulates metallothionein gene expression and zinc metabolism in hepatocyte monolayer cultures.
Topics: Animals; Carbon Tetrachloride; Cell Survival; Cells, Cultured; Dexamethasone; Gene Expression; Interleukin-1; Interleukin-6; Kinetics; Liver; Male; Metallothionein; Rats; Rats, Inbred Strains; Recombinant Proteins; RNA, Messenger; Transcription, Genetic; Zinc | 1990 |
Release of hepatic cadmium by carbon tetrachloride treatment.
Topics: Animals; Cadmium; Carbon Tetrachloride; Kidney; Liver; Male; Metallothionein; Rats; Time Factors; Tissue Distribution | 1981 |
Antioxidative roles of metallothionein and manganese superoxide dismutase induced by tumor necrosis factor-alpha and interleukin-6.
Topics: Acute-Phase Proteins; Animals; Antioxidants; Carbon Tetrachloride; Cytokines; Dexamethasone; Free Radical Scavengers; Gene Expression Regulation, Enzymologic; Glutathione Peroxidase; Interleukin-6; Interleukins; Kidney; Liver; Liver Cirrhosis, Experimental; Male; Metallothionein; Oxidative Stress; Paraquat; Rats; Rats, Wistar; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 1995 |
Effects of mild zinc deficiency, plus or minus acute phase response, on CCl4 hepatotoxicity.
Topics: Acute-Phase Reaction; Animals; Carbon Tetrachloride; Cell Membrane; Chemical and Drug Induced Liver Injury; Glucose-6-Phosphatase; L-Iditol 2-Dehydrogenase; Liver; Male; Metallothionein; Rats; Rats, Sprague-Dawley; Zinc | 1994 |
Metallothionein-independent hepatoprotection by zinc and sakuraso-saponin.
Topics: Animals; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Liver; Male; Metallothionein; Mice; Mice, Inbred Strains; Saponins; Transaminases; Zinc | 1997 |
Protection against carbon tetrachloride hepatotoxicity by oleanolic acid is not mediated through metallothionein.
Topics: Animals; Carbon Tetrachloride; Dose-Response Relationship, Drug; Drug Interactions; Liver; Male; Metallothionein; Mice; Mice, Knockout; Oleanolic Acid; Rats; Rats, Sprague-Dawley | 1998 |
Inhibition of hepatic cell nuclear DNA fragmentation by zinc in carbon tetrachloride-treated rats.
Topics: Animals; Carbon Tetrachloride; DNA Fragmentation; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Male; Metallothionein; Rats; Rats, Wistar; Zinc | 1999 |
Metallothionein and heat shock protein expression during acute liver injury and regeneration in rats.
Topics: Animals; Carbon Tetrachloride; Heat-Shock Proteins; Immunohistochemistry; Liver; Liver Regeneration; Male; Metallothionein; Rats; Rats, Wistar; Thioacetamide | 2000 |
Metallothionein expression protects against carbon tetrachloride-induced hepatotoxicity, but overexpression and dietary zinc supplementation provide no further protection in metallothionein transgenic and knockout mice.
Topics: Alanine Transaminase; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Dietary Supplements; Female; Gene Expression Regulation; Liver; Liver Diseases; Male; Metallothionein; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Microscopy; Oxidative Stress; Time Factors; Zinc | 2001 |
The antioxidant and hepatoprotective effects of zinc are related to hepatic cytochrome P450 depression and metallothionein induction in rats with experimental cirrhosis.
Topics: Administration, Oral; Animals; Carbon Tetrachloride; Catalase; Cytochrome P-450 Enzyme System; Enzyme Induction; Lipid Peroxidation; Liver; Liver Cirrhosis, Experimental; Male; Metallothionein; Rats; Rats, Wistar; Superoxide Dismutase; Zinc | 2001 |
Metallothionein gene therapy for chemical-induced liver fibrosis in mice.
Topics: Animals; Carbon Tetrachloride; Enzyme Activation; Fibrinolysis; Genetic Therapy; Liver Cirrhosis; Metallothionein; Mice; Mice, Knockout | 2004 |
Antifibrotic activity of anthocyanidin delphinidin in carbon tetrachloride-induced hepatotoxicity in mice.
Topics: Animals; Anthocyanins; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Down-Regulation; Drug-Related Side Effects and Adverse Reactions; Fibrosis; Hepatic Stellate Cells; Liver; Liver Cirrhosis; Male; Matrix Metalloproteinase 9; Metallothionein; Mice; Mice, Inbred BALB C; Olive Oil; Plant Oils; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha | 2010 |
The anti-apoptotic effect of fucoxanthin on carbon tetrachloride-induced hepatotoxicity.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Cell Line; Cell Survival; Chemical and Drug Induced Liver Injury; Heme Oxygenase-1; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Metallothionein; Protective Agents; Rats; Rats, Inbred F344; Rats, Wistar; Xanthophylls | 2013 |
Dietary supplementation of blueberry juice enhances hepatic expression of metallothionein and attenuates liver fibrosis in rats.
Topics: Actins; Animals; Beverages; Blueberry Plants; Carbon Tetrachloride; Collagen Type III; Dietary Supplements; Drugs, Chinese Herbal; Gene Expression; Liver; Liver Cirrhosis, Experimental; Male; Malondialdehyde; Metallothionein; Rats; Superoxide Dismutase; Up-Regulation | 2013 |
Carbon tetrachloride-induced lethality in mouse is prevented by multiple pretreatment with zinc sulfate.
Topics: Alanine Transaminase; Animals; Biomarkers; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Free Radical Scavengers; Injections, Intraperitoneal; Injections, Subcutaneous; Lethal Dose 50; Male; Metallothionein; Mice, Inbred Strains; Zinc Sulfate | 2016 |
Carbon Tetrachloride-Induced Nephrotoxicity in Mice Is Prevented by Pretreatment with Zinc Sulfate.
Topics: Animals; Blood Urea Nitrogen; Carbon Tetrachloride; Creatinine; Kidney; Kidney Diseases; Male; Malondialdehyde; Metallothionein; Mice; Zinc Sulfate | 2016 |
Suppressive Effect of Kampo Formula "Juzen-taiho-to" on Carbon Tetrachloride-Induced Hepatotoxicity in Mice.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Calcium; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Drugs, Chinese Herbal; Liver; Male; Malondialdehyde; Medicine, Kampo; Metallothionein; Mice; Phytotherapy | 2016 |