carbon tetrachloride has been researched along with lignans in 49 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (6.12) | 18.7374 |
| 1990's | 10 (20.41) | 18.2507 |
| 2000's | 11 (22.45) | 29.6817 |
| 2010's | 21 (42.86) | 24.3611 |
| 2020's | 4 (8.16) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, DF; Hattori, M; Namba, T; Xu, GJ; Yang, XW | 1 |
| Liu, GT | 2 |
| Lesca, P; Liu, KT | 1 |
| Chen, JX; Jin, HQ; Xie, JX; Yang, JH; Zhang, CZ; Zhou, J | 1 |
| Akamatsu, T; Akimoto, K; Hirose, N; Kitagawa, Y; Shimizu, S; Sugano, M; Yamada, H | 1 |
| Ip, SP; Ko, KM; Li, PC; Mak, DH; Poon, MK | 2 |
| Che, CT; Ip, SP; Ko, KM; Kong, YC; Ng, KH; Poon, MK | 1 |
| Ip, SP; Ko, KM | 1 |
| Che, CT; Ip, SP; Ko, KM; Ma, CY | 1 |
| Ko, KM; Mak, DH | 1 |
| Li, RC; Lin, KF; Yeung, RY; Zhu, M | 1 |
| Cho, JH; Kim, HS; Kim, YC; Lee, EJ; Sung, SH | 1 |
| Kang, SY; Kim, SY; Kim, YC; Lee, EJ; Park, HY; Sung, SH; Yu, YU | 1 |
| Arikawa, J; Endoh, D; Hayashi, M; Kon, Y; Okui, T; Ozawa, S; Yamato, O | 1 |
| Chiu, PY; Ko, KM; Mak, DH; Poon, MK | 1 |
| Chiu, PY; Ko, KM; Mak, DH; Poon, MK; Tang, MH | 1 |
| Jang, YP; Kim, CJ; Kim, JW; Kim, SH; Kim, YC; Sung, SH | 1 |
| Chiu, PY; Ko, KM; Tang, MH | 1 |
| Cao, AH; King, RG; Vo, LT | 1 |
| Chiu, PY; Ko, KM; Leung, HY; Poon, MK; Siu, AH | 1 |
| Chang, CY; Chen, JR; Chen, YL; Huang, CC; Huang, GC; Li, JS; Tsi, D; Yang, SC | 1 |
| Han, T; Jiao, L; Khalid, R; Qin, LP; Yan, F; Zhang, H; Zhang, QY | 1 |
| Dai, C; Hao, H; Kang, A; Li, J; Liang, Y; Sun, S; Wang, G; Xie, L; Xie, T; Xie, Y; Zheng, X | 1 |
| Che, CT; Chen, Y; Ip, SP; Ko, KM; Lai, PB; Mao, QQ; Ng, EW; Poon, TC; Xian, YF | 1 |
| Chen, N; Chiu, PY; Ko, KM; Leong, PK; Leung, H | 1 |
| Aburada, M; Shimada, T; Teraoka, R | 1 |
| Choi, YH; Hong, JT; Hwang, DY; Hwang, IS; Kang, BC; Kim, JE; Kwak, MH; Lee, YJ | 1 |
| Ding, J; Liu, CM; Ma, JQ; Zhang, L | 1 |
| Fan, TY; Hao, XJ; He, T; Huang, LJ; Liu, S; Mu, SZ; Shi, JZ; Wang, QY; Yan, C | 1 |
| Jyothilakshmi, V; Krithika, R; Verma, RJ | 1 |
| Guo, C; Hao, H; Kang, A; Wang, G; Wang, H; Xie, Y | 1 |
| Ahmad, A; Al-Dosari, M; Al-Sohaibani, M; Al-Yahya, M; AlSaid, M; Mothana, R; Rafatullah, S; Raish, M | 1 |
| Chen, H; Han, J; Li, J; Shen, B; Shen, C; Shen, G; Xu, P; Yuan, H | 1 |
| Liu, L; Lv, D; Zhu, CQ | 1 |
| Mishra, SH; Nagar, PA; Rajpara, A; Sethiya, NK; Shah, P | 1 |
| Jyothilakshmi, V; Krithika, R; Prashantha, K; Verma, RJ | 1 |
| Cao, LP; Du, JL; Jia, R; Liu, YJ; Xu, P; Yin, GJ | 1 |
| Abdel-Kader, MS; Amer, ME; El Sohafy, SM; El Toumy, SA; ElSohly, MA; Metwally, AM; Omar, AA; Radwan, MM | 1 |
| Ashour, ML; El-Beshbishy, HA; Singab, AN; Sobeh, M; Wink, M; Youssef, FS | 1 |
| Chicca, A; de Gottardi, A; Gertsch, J; Hampe, J; Moghadamrad, S; Patsenker, E; Petrucci, V; Semmo, N; Stickel, F | 1 |
| Cao, Y; Chen, Q; Li, Y; Sun, S; Zhang, G; Zhang, H; Zhang, J | 1 |
| Fu, XH; Gu, J; Huang, SY; Liu, W; Shi, LL; Shi, YC | 1 |
| Chen, Q; Dahan, A; Tan, W; Wei, L; Xue, J; Zhang, G; Zhang, H | 1 |
| Feng, JM; Gao, GC; Huang, X; Wu, JM; Wu, Z; Xu, JB; Yuan, MJ; Zhang, Y; Zheng, YX; Zhou, HY | 1 |
| Ahmed Hamza, A; Ashour, ML; El-Beshbishy, HA; Singab, ANB; Wink, M; Youssef, FS | 1 |
| Chen, G; Deng, LL; Hao, XJ; Li, J; Mu, SZ; Wang, DP; Xie, XD | 1 |
| Fu, K; Gong, L; Li, Y; Liu, Y; Ma, C; Peng, C; Wang, C | 1 |
2 review(s) available for carbon tetrachloride and lignans
| Article | Year |
|---|---|
Effects of some compounds isolated from Chinese medicinal herbs on hepatic microsomal cytochrome P-450 and their potential biological consequences.
Topics: Acetaminophen; Alkaloids; Animals; Carbon Tetrachloride; Carcinogens; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drugs, Chinese Herbal; Enzyme Induction; Humans; Isoquinolines; Lignans; Lignin; Liver | 1991 |
[Biochemical and pharmacologic effects of wuweizi (Schizandra chinensis (Turcz.) Baill.) and its chemical contents on animal livers].
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cyclooctanes; Cytochrome P-450 Enzyme System; Drugs, Chinese Herbal; Lignans; Liver; Mitochondria, Liver; Polycyclic Compounds | 1988 |
47 other study(ies) available for carbon tetrachloride and lignans
| Article | Year |
|---|---|
Anti-lipid peroxidative effect of an extract of the stems of Kadsura heteroclita and its major constituent, kadsurin, in mice.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Cyclooctanes; Dioxoles; Drugs, Chinese Herbal; Glutathione; Lignans; Lipid Peroxidation; Liver; Male; Mice; Superoxide Dismutase | 1992 |
Pharmacological properties of Dibenzo[a,c]cyclooctene derivatives isolated from Fructus Schizandrae Chinensis III. Inhibitory effects on carbon tetrachloride-induced lipid peroxidation, metabolism and covalent binding of carbon tetrachloride to lipids.
Topics: Animals; Carbon Tetrachloride; China; Cyclooctanes; Dioxoles; Lignans; Lipid Metabolism; Lipid Peroxides; Male; Mice; Mice, Inbred DBA; Microsomes, Liver; NADP; Oxygen Consumption; Plants, Medicinal; Polycyclic Compounds | 1982 |
[Synthesis of Schizandrin C analogs (author's transl)].
Topics: Animals; Carbon Tetrachloride; China; Cyclooctanes; Cycloparaffins; Lignans; Mice; Plant Extracts; Plants, Medicinal; Polycyclic Compounds | 1981 |
Protective effects of sesamin against liver damage caused by alcohol or carbon tetrachloride in rodents.
Topics: Administration, Inhalation; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Dioxoles; Ethanol; Fatty Acid Desaturases; Fatty Acids; Lignans; Lipid Metabolism; Liver Diseases; Male; Mice; Microsomes, Liver; Rats; Rats, Wistar | 1993 |
Enhancement of hepatic glutathione regeneration capacity by a lignan-enriched extract of fructus schisandrae in rats.
Topics: Animals; Carbon Tetrachloride; Female; Glutathione; Lignans; Liver; Rats; Rats, Sprague-Dawley; Time Factors | 1995 |
Schisandrin B protects against carbon tetrachloride toxicity by enhancing the mitochondrial glutathione redox status in mouse liver.
Topics: Alanine Transaminase; Animals; Antioxidants; Carbon Tetrachloride; Cyclooctanes; Enzyme Inhibitors; Female; Free Radicals; Glutathione; Glutathione Disulfide; Glutathione Reductase; Lignans; Mice; Mice, Inbred BALB C; Mitochondria, Liver; Oxidation-Reduction; Polycyclic Compounds | 1996 |
Effects of Schisandrin B and alpha-tocopherol on lipid peroxidation, in vitro and in vivo.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Chlorides; Cyclooctanes; Erythrocyte Membrane; Female; Ferric Compounds; Humans; In Vitro Techniques; Lignans; Lipid Peroxidation; Liver; Membrane Lipids; Mice; Mice, Inbred BALB C; Polycyclic Compounds; Vitamin E | 1996 |
The crucial antioxidant action of schisandrin B in protecting against carbon tetrachloride hepatotoxicity in mice: a comparative study with butylated hydroxytoluene.
Topics: Alanine Transaminase; Animals; Antioxidants; Butylated Hydroxytoluene; Carbon Tetrachloride; Cyclooctanes; Female; Lignans; Liver; Mice; Mice, Inbred BALB C; NADP; Polycyclic Compounds | 1996 |
Methylenedioxy group as determinant of schisandrin in enhancing hepatic mitochondrial glutathione in carbon tetrachloride-intoxicated mice.
Topics: Alanine Transaminase; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cyclooctanes; Drugs, Chinese Herbal; Female; Glutathione; Lignans; Mice; Mice, Inbred BALB C; Mitochondria, Liver; Polycyclic Compounds; Structure-Activity Relationship | 1997 |
Alterations in susceptibility to carbon tetrachloride toxicity and hepatic antioxidant/detoxification system in streptozotocin-induced short-term diabetic rats: effects of insulin and Schisandrin B treatment.
Topics: Alanine Transaminase; Animals; Antioxidants; Blood Glucose; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cyclooctanes; Diabetes Mellitus, Experimental; Glucosephosphate Dehydrogenase; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Insulin; Lignans; Liver; Liver Diseases; Male; Microsomes; Mitochondria, Liver; Oxidation-Reduction; Polycyclic Compounds; Rats; Rats, Sprague-Dawley; Streptozocin | 1997 |
Evaluation of the protective effects of Schisandra chinensis on Phase I drug metabolism using a CCl4 intoxication model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Area Under Curve; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cyclooctanes; Fruit; Hong Kong; Lignans; Liver; Liver Diseases; Male; Medicine, Chinese Traditional; Molecular Probes; Oxidation-Reduction; Plant Extracts; Plants, Medicinal; Polycyclic Compounds; Rats; Rats, Sprague-Dawley; Seeds | 1999 |
Sauchinone, a lignan from Saururus chinensis, attenuates CCl4-induced toxicity in primary cultures of rat hepatocytes.
Topics: Animals; Benzopyrans; Carbon Tetrachloride; Catalase; Cells, Cultured; Dioxoles; Drug Interactions; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Lignans; Liver; Magnoliopsida; Male; Malondialdehyde; Protective Agents; Rats; Rats, Wistar; Superoxide Dismutase | 2000 |
Antioxidant lignans from Machilus thunbergii protect CCl4-injured primary cultures of rat hepatocytes.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Cells, Cultured; Hepatocytes; Lignans; Lipid Peroxidation; Male; Plants, Medicinal; Rats; Rats, Wistar; Structure-Activity Relationship | 2000 |
Protective effect of a lignan-containing flaxseed extract against CCl(4)-induced hepatic injury.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; DNA Damage; Drug Administration Schedule; Flax; Glutathione; Lignans; Liver; Liver Diseases; Necrosis; Plant Extracts; Rats; Rats, Inbred Strains | 2002 |
In vivo antioxidant action of a lignan-enriched extract of Schisandra fruit and an anthraquinone-containing extract of Polygonum root in comparison with schisandrin B and emodin.
Topics: Alanine Transaminase; alpha-Tocopherol; Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cyclooctanes; Emodin; Female; Fruit; Glutathione; L-Iditol 2-Dehydrogenase; Lignans; Mice; Mice, Inbred BALB C; Mitochondria, Liver; Phytotherapy; Plant Extracts; Plant Roots; Polycyclic Compounds; Polygonum; Random Allocation; Schisandra | 2002 |
Hepatoprotective mechanism of schisandrin B: role of mitochondrial glutathione antioxidant status and heat shock proteins.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Carbon Tetrachloride; Cyclooctanes; Dioxoles; Enzyme Inhibitors; Female; Free Radicals; Glutathione; Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Lignans; Liver; Mice; Mice, Inbred BALB C; Mitochondria; Models, Chemical; Molecular Chaperones; Neoplasm Proteins; Oxidative Stress; Polycyclic Compounds; Time Factors | 2003 |
Hepatoprotective dibenzylbutyrolactone lignans of Torreya nucifera against CCl4-induced toxicity in primary cultured rat hepatocytes.
Topics: Animals; Carbon Tetrachloride; Cells, Cultured; Furans; Hepatocytes; Lignans; Male; Plant Bark; Plant Extracts; Rats; Rats, Wistar; Taxaceae | 2003 |
Hepatoprotective action of schisandrin B against carbon tetrachloride toxicity was mediated by both enhancement of mitochondrial glutathione status and induction of heat shock proteins in mice.
Topics: Analysis of Variance; Animals; Antioxidants; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cyclooctanes; Female; Glutathione; Heat-Shock Proteins; Lignans; Liver; Mice; Mice, Inbred BALB C; Mitochondria, Liver; Polycyclic Compounds; Time Factors | 2003 |
Honokiol protects against carbon tetrachloride induced liver damage in the rat.
Topics: Animals; Bilirubin; Biphenyl Compounds; Carbon Tetrachloride; Hepatic Veno-Occlusive Disease; Lignans; Liver; Liver Cirrhosis, Experimental; Magnolia; Male; Microscopy, Confocal; Rats; Rats, Long-Evans | 2005 |
Schisandrin B decreases the sensitivity of mitochondria to calcium ion-induced permeability transition and protects against carbon tetrachloride toxicity in mouse livers.
Topics: Animals; Calcium; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cell Membrane Permeability; Cyclooctanes; Cytochromes c; Female; Ions; Lignans; Membrane Potentials; Mice; Mice, Inbred BALB C; Mitochondria, Liver; Molecular Structure; Polycyclic Compounds; Reactive Oxygen Species; Time Factors | 2007 |
Effect of schisandrin B and sesamin mixture on CCl(4)-induced hepatic oxidative stress in rats.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cyclooctanes; Dioxoles; Drug Combinations; Drugs, Chinese Herbal; Glutathione; Glutathione Peroxidase; Lignans; Liver; Liver Diseases; Male; Oxidative Stress; Polycyclic Compounds; Rats; Rats, Sprague-Dawley; Silymarin; Superoxide Dismutase | 2009 |
Synergistic hepatoprotective effect of Schisandrae lignans with Astragalus polysaccharides on chronic liver injury in rats.
Topics: Animals; Astragalus propinquus; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chronic Disease; Drug Synergism; Drug Therapy, Combination; Enzymes; Fatty Liver; Fruit; Lignans; Liver; Male; Malondialdehyde; Phytotherapy; Plant Extracts; Plant Roots; Polysaccharides; Protective Agents; Rats; Rats, Sprague-Dawley; Schisandra | 2009 |
Integral pharmacokinetics of multiple lignan components in normal, CCl4-induced hepatic injury and hepatoprotective agents pretreated rats and correlations with hepatic injury biomarkers.
Topics: Alanine Transaminase; Animals; Area Under Curve; Aspartate Aminotransferases; Biomarkers; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP3A; Dioxoles; Disease Models, Animal; Down-Regulation; Female; Fruit; Herb-Drug Interactions; Lignans; Male; Phytotherapy; Plant Extracts; Protective Agents; Rats; Rats, Sprague-Dawley; Reference Values; Schisandra | 2010 |
A proteomic approach in investigating the hepatoprotective mechanism of Schisandrin B: role of raf kinase inhibitor protein.
Topics: Animals; Apoptosis; Blotting, Western; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cyclooctanes; Electrophoresis, Gel, Two-Dimensional; Extracellular Signal-Regulated MAP Kinases; Lignans; Male; MAP Kinase Kinase Kinases; Mice; Mice, Inbred BALB C; Phosphatidylethanolamine Binding Protein; Polycyclic Compounds; Protective Agents; Proteins; Proteome; Proteomics; Proto-Oncogene Proteins c-raf; Signal Transduction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Statistics, Nonparametric | 2011 |
Schisandrin B elicits a glutathione antioxidant response and protects against apoptosis via the redox-sensitive ERK/Nrf2 pathway in AML12 hepatocytes.
Topics: Animals; Antioxidants; Apoptosis; Butadienes; Carbon Tetrachloride; Cell Line; Cyclooctanes; Cytoprotection; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression; Glutathione; Hepatocytes; Lignans; MAP Kinase Kinase 4; Mice; Mice, Inbred BALB C; NF-E2-Related Factor 2; Nitriles; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Polycyclic Compounds; Reactive Oxygen Species; RNA, Small Interfering; Signal Transduction; Vitamin K 3 | 2011 |
The molecular mechanisms of the hepatoprotective effect of gomisin A against oxidative stress and inflammatory response in rats with carbon tetrachloride-induced acute liver injury.
Topics: Actins; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cyclooctanes; Dioxoles; Interleukin-1beta; Lignans; Lipid Peroxidation; Male; Malondialdehyde; NF-kappa B; Nitric Oxide Synthase Type II; Oxidative Stress; Protective Agents; Rats; Rats, Wistar; RNA, Messenger; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Tumor Necrosis Factor-alpha | 2012 |
Protective effects of gomisin A isolated from Schisandra chinensis against CCl(4)-induced hepatic and renal injury.
Topics: Acute Kidney Injury; Analysis of Variance; Animals; Apoptosis; Body Weight; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cyclooctanes; Dioxoles; Kidney; Lignans; Liver; MAP Kinase Signaling System; Organ Size; Phosphorylation; Protective Agents; Rats; Rats, Sprague-Dawley; Schisandra | 2013 |
Hepatoprotective properties of sesamin against CCl4 induced oxidative stress-mediated apoptosis in mice via JNK pathway.
Topics: Animals; Apoptosis; Carbon Tetrachloride; Caspase 3; Chemical and Drug Induced Liver Injury; Dioxoles; Enzyme Activation; Lignans; Liver; Male; MAP Kinase Kinase 4; Mice; Mice, Inbred ICR; Oxidative Stress; Phosphorylation; Reactive Oxygen Species | 2014 |
Synthesis and the hepatoprotective activity of dibenzocyclooctadiene lignan derivatives.
Topics: Carbon Tetrachloride; Cell Survival; Cyclooctanes; Dose-Response Relationship, Drug; Humans; Lignans; Liver; Molecular Conformation; Structure-Activity Relationship | 2014 |
Phyllanthin inhibits CCl4-mediated oxidative stress and hepatic fibrosis by down-regulating TNF-α/NF-κB, and pro-fibrotic factor TGF-β1 mediating inflammatory signaling.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Down-Regulation; Female; Hep G2 Cells; Humans; Lignans; Lipid Peroxidation; Liver; Liver Cirrhosis; Mice; NF-kappa B; Oxidative Stress; Phyllanthus; Plant Extracts; Protective Agents; RNA, Messenger; Signal Transduction; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha | 2016 |
Reversing effects of lignans on CCl4-induced hepatic CYP450 down regulation by attenuating oxidative stress.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Cyclooctanes; Cytochrome P-450 Enzyme System; Dioxoles; Down-Regulation; Hep G2 Cells; Humans; Lignans; Liver; Liver Diseases; Male; Oxidative Stress; Plant Extracts; Polycyclic Compounds; Rats; Rats, Sprague-Dawley; Schisandra | 2014 |
Evaluation of the effectiveness of Piper cubeba extract in the amelioration of CCl4-induced liver injuries and oxidative damage in the rodent model.
Topics: Animals; Antioxidants; Biphenyl Compounds; Carbon Tetrachloride; Catalase; Chemical and Drug Induced Liver Injury; Cytokines; Disease Models, Animal; Ethanol; Free Radical Scavengers; Lignans; Liver; Male; Malondialdehyde; Oxidative Stress; Phytochemicals; Picrates; Piper; Plant Extracts; Protective Agents; Rats, Wistar; RNA, Messenger; Sulfhydryl Compounds | 2015 |
Hepatoprotective effects of lignans extract from Herpetospermum caudigerum against CCl₄-induced acute liver injury in mice.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cucurbitaceae; Furans; Glutathione; Glutathione Peroxidase; Lignans; Liver; Malondialdehyde; Mice; Phytotherapy; Plant Extracts; Protective Agents; Seeds; Superoxide Dismutase | 2015 |
Sesamin ameliorates oxidative liver injury induced by carbon tetrachloride in rat.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Dioxoles; Disease Models, Animal; Lignans; Lipid Peroxidation; Male; Oxidative Stress; Rats; Rats, Wistar | 2015 |
Antioxidant and hepatoprotective effects of mixed micellar lipid formulation of phyllanthin and piperine in carbon tetrachloride-induced liver injury in rodents.
Topics: Administration, Oral; Alkaloids; Animals; Antioxidants; Benzodioxoles; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chemistry, Pharmaceutical; Cytochrome P-450 Enzyme Inhibitors; Glutathione; Glutathione Peroxidase; Lignans; Lipid Peroxidation; Lipids; Liver; Male; Piperidines; Plant Extracts; Polyunsaturated Alkamides; Protective Agents; Rats; Rats, Wistar; Silymarin | 2015 |
Mechanism of protective effect of phyllanthin against carbon tetrachloride-induced hepatotoxicity and experimental liver fibrosis in mice.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Collagen; Female; Lignans; Liver Cirrhosis; Liver Function Tests; Mice; Molecular Docking Simulation; Phyllanthus; Protective Agents; Protein Binding; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta1 | 2015 |
Protective action of the phyllanthin against carbon tetrachloride-induced hepatocyte damage in Cyprinus carpio.
Topics: Animals; Carbon Tetrachloride; Carps; Cell Survival; Fish Diseases; Hepatocytes; Lignans; Liver; Protective Agents | 2016 |
Cornigerin, a new sesqui-lignan from the hepatoprotective fractions of Cynara cornigera L.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chemical Fractionation; Cynara; Lignans; Male; Plant Extracts; Rats, Wistar | 2016 |
Eremophila maculata-Isolation of a rare naturally-occurring lignan glycoside and the hepatoprotective activity of the leaf extract.
Topics: Animals; Antioxidants; Australia; Carbon Tetrachloride; Cardiac Glycosides; Female; Furans; Glycosides; Hep G2 Cells; Hepatocytes; Humans; Lignans; Liver; Male; Molecular Docking Simulation; Oxidative Stress; Phytotherapy; Plant Extracts; Plant Leaves; Rats, Sprague-Dawley; Scrophulariaceae; Silymarin; Tumor Necrosis Factor-alpha | 2016 |
4-O'-methylhonokiol protects from alcohol/carbon tetrachloride-induced liver injury in mice.
Topics: Animals; Biphenyl Compounds; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Endocannabinoids; Lignans; Liver; Liver Cirrhosis; Liver Diseases, Alcoholic; Magnolia; Male; Mice, Inbred C57BL; Protective Agents | 2017 |
Schisandrin B attenuates CCl
Topics: Animals; Carbon Tetrachloride; Cyclooctanes; Lignans; Liver Cirrhosis; Male; Molecular Structure; NF-E2-Related Factor 2; Polycyclic Compounds; Rats; Rats, Wistar; Signal Transduction; Smad Proteins; Transforming Growth Factor beta | 2017 |
[Protective effect and mechanism of total lignans from Tibetan medicinal Herpetospermum seeds on carbon tetrachloride-induced liver fibrosis in rats].
Topics: Animals; Carbon Tetrachloride; Cucurbitaceae; Lignans; Liver; Liver Cirrhosis; Male; Rats; Rats, Sprague-Dawley; Seeds; Tibet | 2017 |
Transcriptomic analyses reveal the molecular mechanisms of schisandrin B alleviates CCl
Topics: Animals; Apoptosis; Carbon Tetrachloride; Cyclooctanes; Down-Regulation; Endoplasmic Reticulum Stress; Gene Expression Profiling; Lignans; Liver; Liver Cirrhosis; Male; Medicine, Chinese Traditional; Polycyclic Compounds; Rats; Rats, Wistar; RNA; Schisandra; Sequence Analysis, RNA; Signal Transduction; Transcriptome; Up-Regulation | 2019 |
Lignans from Schisandra chinensis ameliorate alcohol and CCl
Topics: Animals; Antioxidants; Apoptosis; Carbon Tetrachloride; Cell Line; Chemical and Drug Induced Liver Injury; Computer Simulation; Disease Models, Animal; Hepatic Stellate Cells; Hepatocytes; Humans; Lignans; Liver Diseases, Alcoholic; Male; Mice; Mice, Inbred C57BL; Plant Extracts; Receptor, Endothelin B; Schisandra | 2020 |
Pinoresinol-4-O-β-D-glucopyranoside: a lignan from prunes (Prunus domestica) attenuates oxidative stress, hyperglycaemia and hepatic toxicity in vitro and in vivo.
Topics: alpha-Amylases; alpha-Glucosidases; Animals; Antioxidants; Blood Glucose; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Diabetes Mellitus, Experimental; Fruit; Glucosides; Glycoside Hydrolase Inhibitors; Insulin; Lignans; Liver; Male; Mice; Molecular Docking Simulation; Oxidative Stress; Plant Extracts; Prunus domestica; Streptozocin | 2020 |
Hepatoprotective Constituents of Total Dibenzocyclooctadiene Lignans from
Topics: Animals; Carbon Tetrachloride; Cell Survival; Cells, Cultured; Cluster Analysis; Cyclooctanes; Least-Squares Analysis; Lignans; Liver; Mice; Molecular Structure; Protective Agents; Schisandra | 2021 |
Hepatoprotective effect of phillygenin on carbon tetrachloride-induced liver fibrosis and its effects on short chain fatty acid and bile acid metabolism.
Topics: Animals; Bile Acids and Salts; Carbon Tetrachloride; Fatty Acids, Volatile; Lignans; Liver; Liver Cirrhosis; Mice; Mice, Inbred C57BL | 2022 |