Page last updated: 2024-08-17

carbon tetrachloride and dimethylnitrosamine

carbon tetrachloride has been researched along with dimethylnitrosamine in 67 studies

Research

Studies (67)

Timeframe	Studies, this research(%)	All Research%
pre-1990	39 (58.21)	18.7374
1990's	14 (20.90)	18.2507
2000's	7 (10.45)	29.6817
2010's	7 (10.45)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Shires, TK	1
Chopra, P; Das, PK; Dhar, A; Mital, I; Nayak, NC	1
Das, PK; Mittal, A; Mohanty, M; Nayak, NC	1
Chopra, P; Das, PK; Dhar, A; Nayak, NC	1
Mitchell, JR; Potter, WZ; Sasame, HA; Thorgeirsson, SS	1
Parkin, R; Stoddart, DJ; Waynforth, HB	1
Bragaglia, RB; Grilli, S; Prodi, G	1
Farber, E; Gruenstein, M; Parker, S	1
Pound, AW	1
Lawson, TA; Pound, AW	3
Khan, S; Lauriault, VV; O'Brien, PJ	1
Kato, K; Koga, N; Maeda, S; Oka, M; Saito, T	1
Blankenship, LJ; Clawson, GA; Rhame, JG; Wilkinson, DS	1
Iwai, M; Miyashita, T; Shimazu, T; Takeda, A	1
Brady, JF; Gapac, JM; Li, Y; Ning, SM; Wang, MH; Xiao, F; Yang, CS	1
Fujiwara, K; Mochida, S; Ogata, I; Tomiya, T	1
Baraona, E; Hernández-Muñoz, R; Lieber, CS; Ma, XL	1
Fujiwara, K; Hirata, K; Ogata, I; Ohta, Y	1
Furihata, C; Matsushima, T; Sawada, S	1
Braye, S; Fleming, J; Karran, S; McLaren, M; Taylor, I	1
Höfer, M; Lee, KS; Lie, TS; Nakajima, Y; Nakano, H; Otani, Y	1
Mori, H; Tanaka, T; Williams, GM	1
Iwai, M; Shimazu, T	1
Fujiwara, K; Masaki, N; Ogata, I; Ohta, Y; Oka, H; Oka, Y; Sato, Y; Takatsuki, K	1
Fujiwara, K; Hirata, K; Masaki, N; Ogata, I; Ohta, Y; Oka, H; Oka, Y; Sato, Y; Yamada, S	1
Kazachkov, VI; Litvinov, NN; Voronin, VM	2
Baldaeva, LL; Bonashevskaia, TI; Fetisov, VV; Lamentova, TG; Shamarin, AA	1
Landon, EJ; Naukam, RJ; Rama Sastry, BV	1
Sudoh, A; Umezu, K; Yuasa, S	1
Anders, MW; Aniya, Y	1
Kärki, NT; Saarni, HU; Sotaniemi, EA; Stengård, J	1
Saarni, HU; Sotaniemi, EA; Stengård, JH	1
Adams, JD; Lauterburg, BH; Mitchell, JR	1
Hughes, H; Mitchell, JR; Smith, CV	1
Mostafa, MH; Ruchirawat, M; Shank, RC; Weisburger, EK	1
Barbin, A; Bartsch, H; Béréziat, JC	1
Mostafa, MH; Ruchirawat, M; Weisburger, EK	1
Wang, GM	1
Asakura, S; Daimon, H; Fukuda, T; Furihata, C; Ogura, K; Sawada, S; Yamatsu, K	1
Arai, M; Fujiwara, K; Hirata, K; Masaki, N; Matsui, A; Mochida, S; Nagoshi, S; Ohno, A; Tomiya, T; Yamaoka, M	1
Miyamoto, K	1
Asakura, H; Ichida, T; Komoriya, Y; Matsuda, Y; Matsumoto, K; Nakamura, T; Nishiyama, E; Yamada, A	1
Fujise, N; Higashio, K; Masunaga, H; Shiota, A; Yamashita, Y; Yasuda, H	1
Fujise, N; Higashio, K; Masunaga, H; Ogawa, H; Shiota, A; Yamashita, Y; Yasuda, H	1
Fujiwara, K; Ogata, I; Tomiya, T	1
Inoue, K; Mizuoka, H; Shikata, N; Takasu, M; Tsubura, A; Yang, J	1
Calès, P; Fort, J; Kaassis, M; Moal, F; Oberti, F; Pilette, C; Veal, N; Vuillemin, E	1
Hirakawa, K; Ikebe, T; Ikeda, K; Kaneda, K; Kawada, N; Nakatani, K; Sowa, M; Wang, YQ	1
Butterworth, BE; Mirsalis, JC	1
Cai, WM; Liu, RH; Weng, HL	1
Casini, A; Ceni, E; Crabb, DW; Galli, A; Mello, T; Ridolfi, F; Salzano, R; Surrenti, C; Svegliati-Baroni, G; Trozzi, L	1
BORNSTEIN, S; HALBREICH, A; MAGER, J	2
Chen, R; Lei, JX; Li, SN; Xiang, P; Yu, WH; Zhang, XM; Zhao, DC	1
Kato, H; Katoh, M; Minami, K; Nakajima, M; Narahara, M; Saito, T; Sugiyama, H; Tomita, H; Yokoi, T	1
Chun, J; Fujita, R; Iitsuka, S; Ikeda, H; Inoue, Y; Ishii, I; Kume, Y; Nishikawa, T; Ohtomo, N; Omata, M; Shimosawa, T; Tanoue, Y; Tomiya, T; Watanabe, N; Yatomi, Y	1
Hu, Y; Jian, P; Liu, C; Liu, P; Peng, J; Sun, M; Tao, Q; Wu, JZ; Yang, W	1
Jin, L; Shan, W; Shu, D; Wang, H; Wang, T; Wu, J; Xiong, S; Zhang, S	1
Li, W; Pu, XP; Sun, H; Sun, Y; Wang, YH; Yang, YF; Zhao, X; Zheng, XY	1
Choi, MK; Han, JM; Kim, HG; Lee, JS; Park, HJ; Son, CG; Wang, JH	1
Bak, J; Cheong, KO; Chung, HY; Je, NK; Kim, KW; Lee, C; Moon, JO; Shin, DS; Yoon, S	1

Trials

1 trial(s) available for carbon tetrachloride and dimethylnitrosamine

Article	Year
Animal experiment and clinical study of effect of gamma-interferon on hepatic fibrosis. World journal of gastroenterology, 2001, Volume: 7, Issue:1 Topics: Animals; Antineoplastic Agents; Biopsy; Carbon Tetrachloride; Dimethylnitrosamine; Disease Models, Animal; Female; Hepatitis B, Chronic; Humans; Hyaluronic Acid; Hydroxyproline; Interferon-gamma; Liver; Liver Cirrhosis; Liver Function Tests; Male; Rats; Rats, Sprague-Dawley; Recombinant Proteins	2001

Article

Year

Animal experiment and clinical study of effect of gamma-interferon on hepatic fibrosis.

World journal of gastroenterology, 2001, Volume: 7, Issue:1

Topics: Animals; Antineoplastic Agents; Biopsy; Carbon Tetrachloride; Dimethylnitrosamine; Disease Models, Animal; Female; Hepatitis B, Chronic; Humans; Hyaluronic Acid; Hydroxyproline; Interferon-gamma; Liver; Liver Cirrhosis; Liver Function Tests; Male; Rats; Rats, Sprague-Dawley; Recombinant Proteins

2001

Other Studies

66 other study(ies) available for carbon tetrachloride and dimethylnitrosamine

Article	Year
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Lipoperoxidative effects on liver rough microsomal membranes and the ribosome-membrane complex: studies in vitro and in vivo with chemical carcinogens and carbon tetrachloride. Laboratory investigation; a journal of technical methods and pathology, 1978, Volume: 38, Issue:6 Topics: Aflatoxins; Amino Acids; Animals; Carbon Tetrachloride; Carcinogens; Dimethylnitrosamine; In Vitro Techniques; Liver; Male; Membrane Lipids; Membranes; Microsomes, Liver; NADP; p-Dimethylaminoazobenzene; Potassium; Rats; Ribosomes	1978
Increase in serum alpha foetoprotein level in hepatic regeneration of the rat. Effects of age and of magnitude of regenerative activity. British journal of experimental pathology, 1975, Volume: 56, Issue:2 Topics: Age Factors; alpha-Fetoproteins; Animals; Carbon Tetrachloride; Counterimmunoelectrophoresis; Diffusion; Dimethylnitrosamine; Fetal Proteins; Hepatectomy; Liver; Liver Regeneration; Male; Mitosis; Rats	1975
Cellular basis of induced alpha-fetoprotein synthesis by hepatocytes of adult mouse after hepatotoxic injury and partial hepatectomy. International journal of cancer, 1978, Aug-15, Volume: 22, Issue:2 Topics: alpha-Fetoproteins; Animals; Carbon Tetrachloride; Cell Division; Dimethylnitrosamine; Female; Hepatectomy; Liver; Liver Regeneration; Male; Mice; Time Factors	1978
Diverse mechanisms of hepatocellular injuries due to chemicals: evidence in rats administered carbon tetrachloride or dimethylnitrosamine. British journal of experimental pathology, 1975, Volume: 56, Issue:2 Topics: Age Factors; Animals; Animals, Newborn; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; Fetus; Glucose-6-Phosphatase; Hepatectomy; Liver; Liver Diseases; Necrosis; Nitrosamines; Phenobarbital; Rats; Triglycerides	1975
Biochemical changes after hepatic injury by allyl alcohol and N-hydroxy-2-acetylaminofluorene. Chemico-biological interactions, 1976, Oct-02, Volume: 15, Issue:2 Topics: Acetaminophen; Allyl Compounds; Aniline Hydroxylase; Animals; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Cytochromes; Cytosol; Dimethylnitrosamine; Ethylmorphine-N-Demethylase; Fluorenes; Furosemide; Glucose-6-Phosphatase; Hydroxyacetylaminofluorene; Liver; Liver Regeneration; Male; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Nitrogenase; Proteins; Rats	1976
The effect of a protein-free diet, a sugar diet and of carbon tetrachloride administration on the toxicity and rate of metabolism of dimethylnitrosamine in different rat strains. British journal of experimental pathology, 1977, Volume: 58, Issue:2 Topics: Animals; Carbon Tetrachloride; Dietary Carbohydrates; Dimethylnitrosamine; Nitrosamines; Protein Deficiency; Rats; Rats, Inbred Strains	1977
An in vitro study on the interaction between dimethylnitrosamine and nucleic acids via a microsomal system. Gan, 1977, Volume: 68, Issue:2 Topics: Animals; Carbon Tetrachloride; Dimethylnitrosamine; DNA; Ethionine; Female; Guanine; Hydrolysis; In Vitro Techniques; Magnetic Resonance Spectroscopy; Methylamines; Microsomes, Liver; Monomethylhydrazine; Nitrosamines; Polycyclic Compounds; Rats	1977
The resistance of putative premalignant liver cell populations, hyperplastic nodules, to the acute cytotoxic effects of some hepatocarcinogens. Cancer research, 1976, Volume: 36, Issue:11 Pt 1 Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Carcinogens; Cell Transformation, Neoplastic; Dimethylnitrosamine; DNA; Drug Resistance; Ethionine; Hyperplasia; Liver; Liver Neoplasms; Male; Precancerous Conditions; Proteins; Rats; Rats, Inbred F344; RNA	1976
The effect of a dose of dimethylnitrosamine on the toxicity of a subsequent dose and on the toxicity of carbon tetrachloride in mice. British journal of experimental pathology, 1975, Volume: 56, Issue:3 Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; Drug Interactions; Lethal Dose 50; Liver; Male; Mice; Nitrosamines; Time Factors	1975
Protection by carbon tetrachloride against the toxic effects of dimethylnitrosamine in mice. British journal of experimental pathology, 1975, Volume: 56, Issue:1 Topics: Animals; Carbon Tetrachloride; Dimethylnitrosamine; Lethal Dose 50; Liver; Male; Mice; Microsomes, Liver; Necrosis; Nitrosamines; Oxidoreductases, N-Demethylating; Time Factors	1975
Reduction of carbon tetrachloride toxicity by prior administration of a single small dose in mice and rats. British journal of experimental pathology, 1975, Volume: 56, Issue:2 Topics: Animals; Carbon Tetrachloride; Dimethylnitrosamine; Ether; Lethal Dose 50; Liver; Male; Mice; Premedication; Promethazine; Rats; Time Factors	1975
Partial hepatectomy and toxicity of dimethyl-nitrosamine and carbon tetrachloride, in relation to the carcinogenic action of dimethylnitrosamine. British journal of cancer, 1975, Volume: 32, Issue:5 Topics: Animals; Carbon Tetrachloride; Dimethylnitrosamine; Hepatectomy; Kidney Neoplasms; Lethal Dose 50; Liver Neoplasms; Male; Mice; Microsomes, Liver; Mitosis; Nitrosamines; Rats	1975
Hepatocyte cytotoxicity induced by various hepatotoxins mediated by cytochrome P-450IIE1: protection with diethyldithiocarbamate administration. Chemico-biological interactions, 1992, Volume: 81, Issue:3 Topics: Animals; Carbon Disulfide; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Disulfiram; Ditiocarb; Liver Diseases; Male; Microsomes, Liver; NADP; Oxidoreductases, N-Demethylating; Pyrazoles; Rats; Rats, Inbred Strains	1992
A modified colorimetric MTT assay adapted for primary cultured hepatocytes: application to proliferation and cytotoxicity assays. Bioscience, biotechnology, and biochemistry, 1992, Volume: 56, Issue:9 Topics: Carbon Tetrachloride; Cell Count; Cell Division; Cells, Cultured; Colorimetry; Dimethylnitrosamine; Galactosamine; Liver; Tetrazolium Salts; Thiazoles; Toxicology	1992
Nuclear enlargement induced by hepatocarcinogens alters ploidy. Cancer research, 1992, Mar-01, Volume: 52, Issue:5 Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Cell Nucleus; Dimethylnitrosamine; Diploidy; Liver; Male; Polyploidy; Rats; Rats, Inbred Strains; Thioacetamide	1992
Single administration of hepatotoxic chemicals transiently decreases the gap-junction-protein levels of connexin 32 in rat liver. European journal of biochemistry, 1991, Feb-26, Volume: 196, Issue:1 Topics: Alanine Transaminase; Animals; Carbon Tetrachloride; Connexins; Dimethylnitrosamine; DNA; Dose-Response Relationship, Drug; Liver; Liver Regeneration; Male; Membrane Proteins; Rats; Rats, Inbred Strains	1991
Effects of disulfiram on hepatic P450IIE1, other microsomal enzymes, and hepatotoxicity in rats. Toxicology and applied pharmacology, 1991, Volume: 108, Issue:2 Topics: Animals; Carbon Tetrachloride; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Disulfiram; Ditiocarb; Liver; Male; Microsomes, Liver; Oxidoreductases, N-Demethylating; Oxygenases; Rats; Rats, Inbred Strains	1991
Minor contribution of hepatocytes to collagen production in normal and early fibrotic rat livers. Hepatology (Baltimore, Md.), 1991, Volume: 14, Issue:2 Topics: Amino Acids; Animals; Carbon Tetrachloride; Collagen; Dimethylnitrosamine; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Male; Protein Biosynthesis; Rats; Rats, Inbred F344; Reference Values; Serum Albumin; Time Factors	1991
High levels of acetaldehyde in nonalcoholic liver injury after threonine or ethanol administration. Hepatology (Baltimore, Md.), 1989, Volume: 10, Issue:6 Topics: Acetaldehyde; Alcohol Oxidoreductases; Animals; Carbon Tetrachloride; Dimethylnitrosamine; Ethanol; Fatty Liver; Glycine Hydroxymethyltransferase; Liver; Liver Cirrhosis, Experimental; Male; Mitochondria, Liver; Rats; Rats, Inbred Strains; Threonine; Threonine Dehydratase	1989
Hepatic sinusoidal cell destruction in the development of intravascular coagulation in acute liver failure of rats. The Journal of pathology, 1989, Volume: 158, Issue:2 Topics: Animals; Carbon Tetrachloride; Cell Survival; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; Disseminated Intravascular Coagulation; Endothelium, Vascular; Fibrin; Liver; Liver Diseases; Male; Microscopy, Electron; Rats	1989
In vivo short-term assays of repair and replication of rat liver DNA. Journal of cancer research and clinical oncology, 1989, Volume: 115, Issue:4 Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Dimethylnitrosamine; DNA; DNA Repair; DNA Replication; Liver; Male; Rats; Rats, Inbred F344	1989
Changes in blood flow, portal pressure and shunting during the development of cirrhosis in response to beta-blockade. Gut, 1987, Volume: 28, Issue:6 Topics: Adrenergic beta-Antagonists; Animals; Carbon Tetrachloride; Dimethylnitrosamine; Liver; Liver Cirrhosis, Experimental; Male; Portal Vein; Rats; Rats, Inbred Strains; Regional Blood Flow; Venous Pressure	1987
Alteration of thymus and of immune regulatory-antifibroblast factors in acute and chronic hepatic damage. Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1987, Volume: 187, Issue:3 Topics: Acute Disease; Animals; Carbon Tetrachloride; Cell Count; Cell Division; Chronic Disease; Dimethylnitrosamine; Fibroblasts; Liver Cirrhosis, Experimental; Liver Extracts; Lymphocyte Culture Test, Mixed; Male; Rats; Rats, Inbred Lew; Rats, Inbred Strains; T-Lymphocytes; Thymus Gland	1987
Enhancement of dimethylnitrosamine-initiated hepatocarcinogenesis in hamsters by subsequent administration of carbon tetrachloride but not phenobarbital or p,p'-dichlorodiphenyltrichloroethane. Carcinogenesis, 1987, Volume: 8, Issue:9 Topics: Animals; Carbon Tetrachloride; Cocarcinogenesis; Cricetinae; DDT; Dimethylnitrosamine; Liver Neoplasms, Experimental; Male; Mesocricetus; Phenobarbital; Species Specificity	1987
Effects of ventromedial and lateral hypothalamic stimulation on chemically-induced liver injury in rats. Life sciences, 1988, Volume: 42, Issue:19 Topics: Alanine Transaminase; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Denervation; Dimethylnitrosamine; Electric Stimulation; Hypothalamus; Hypothalamus, Middle; Liver; Liver Diseases; Male; Rats; Rats, Inbred Strains; Sympathetic Nervous System	1988
Exchange blood transfusion for acute hepatic failure: its limited availability depending on the type of injury in rats. Artificial organs, 1988, Volume: 12, Issue:3 Topics: Acute Disease; Alanine Transaminase; Animals; Blood Coagulation; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; Exchange Transfusion, Whole Blood; Liver; Liver Diseases; Male; Protein Biosynthesis; Rats; Rats, Inbred Strains	1988
Intravascular coagulation in acute liver failure in rats and its treatment with antithrombin III. Gut, 1988, Volume: 29, Issue:8 Topics: Animals; Antithrombin III; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; Liver; Liver Diseases; Male; Microscopy, Electron; Rats; Rats, Inbred Strains; Thrombosis	1988
[Carcinogenesis-modifying properties of aniline, carbon tetrachloride, benzene and ethanol]. Eksperimental'naia onkologiia, 1986, Volume: 8, Issue:2 Topics: Aniline Compounds; Animals; Benzene; Carbon Tetrachloride; Dimethylnitrosamine; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Female; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Neoplasms, Experimental; Time Factors	1986
[Possibility of predicting the hepatotoxic and neurotoxic effects of a number of chemical substances by morphological indices]. Gigiena i sanitariia, 1986, Issue:6 Topics: Animals; Carbon Monoxide; Carbon Tetrachloride; Dimethylnitrosamine; Dose-Response Relationship, Drug; Environmental Exposure; Liver; Male; Microscopy, Electron; Nervous System; Prognosis; Rats; Time Factors	1986
Effects of calcium channel blocking agents on calcium and centrilobular necrosis in the liver of rats treated with hepatotoxic agents. Biochemical pharmacology, 1986, Feb-15, Volume: 35, Issue:4 Topics: Acetaminophen; Animals; Calcium; Calcium Channel Blockers; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chloroform; Dimethylnitrosamine; Liver; Male; Microsomes, Liver; Necrosis; Rats; Rats, Inbred Strains; Thioacetamide	1986
Change of hepatic histamine content during hepatic fibrosis. Biochemical pharmacology, 1985, Jun-01, Volume: 34, Issue:11 Topics: Animals; Carbon Tetrachloride; Collagen; Dimethylnitrosamine; Histamine; Histamine N-Methyltransferase; Liver; Male; Rats; Rats, Inbred Strains	1985
Alteration of hepatic glutathione S-transferases and release into serum after treatment with bromobenzene, carbon tetrachloride, or N-nitrosodimethylamine. Biochemical pharmacology, 1985, Dec-15, Volume: 34, Issue:24 Topics: Animals; Bromobenzenes; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Cytosol; Dimethylnitrosamine; Ethanol; Glutathione Transferase; Liver; Male; Phenobarbital; Rats; Rats, Inbred Strains	1985
Medroxyprogesterone acetate improvement of the hepatic drug-metabolizing enzyme system in rats after chemical liver injury. Biochemical pharmacology, 1983, Mar-15, Volume: 32, Issue:6 Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; Disease Models, Animal; Enzyme Induction; Female; Liver Regeneration; Medroxyprogesterone; Medroxyprogesterone Acetate; Microsomes, Liver; Protein Biosynthesis; Rats; Rats, Inbred Strains	1983
Effects of medroxyprogesterone acetate on hepatic glucose metabolism and microsomal enzyme activity in rats with normal and altered liver. Pharmacology, 1984, Volume: 28, Issue:1 Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Female; Glucose; Glucose-6-Phosphatase; Liver Diseases; Liver Glycogen; Medroxyprogesterone; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Rats; Rats, Inbred Strains	1984
Plasma glutathione disulfide as an index of oxidant stress in vivo: effects of carbon tetrachloride, dimethylnitrosamine, nitrofurantoin, metronidazole, doxorubicin and diquat. Research communications in chemical pathology and pharmacology, 1984, Volume: 46, Issue:3 Topics: Animals; Carbon Tetrachloride; Dimethylnitrosamine; Diquat; Doxorubicin; Glutathione; Glutathione Disulfide; Male; Metronidazole; Nitrofurantoin; Oxidation-Reduction; Rats; Rats, Inbred Strains	1984
[Characteristics of aniline, lead nitrate, carbon tetrachloride and formaldehyde as modifiers of chemical carcinogenesis]. Voprosy onkologii, 1984, Volume: 30, Issue:4 Topics: Aniline Compounds; Animals; Carbon Tetrachloride; Dimethylnitrosamine; Dose-Response Relationship, Drug; Drug Interactions; Female; Formaldehyde; Lead; Mice; Neoplasms, Experimental; Nitrates; Time Factors	1984
Free radicals in vivo. Covalent binding to lipids. Molecular pharmacology, 1984, Volume: 26, Issue:1 Topics: Acetaminophen; Animals; Bromobenzenes; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemistry; Dimethylnitrosamine; Free Radicals; Furans; Furosemide; Lipid Metabolism; Liver; Male; Mice; Mice, Inbred ICR; Rats; Rats, Inbred Strains	1984
[Studies on comprehensive evaluation of toxic liver injury (author's transl)]. Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences, 1981, Volume: 99 Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; Hematologic Tests; Liver; Liver Diseases; Male; p-Dimethylaminoazobenzene; Rats; Rats, Inbred Strains	1981
Inhibitory effects of carbon tetrachloride on dimethylnitrosamine metabolism and DNA alkylation. Carcinogenesis, 1983, Volume: 4, Issue:5 Topics: Alkylation; Animals; Carbon Tetrachloride; Diet; Dimethylnitrosamine; DNA; Dose-Response Relationship, Drug; Indoles; Male; Rats	1983
Evaluation of DNA damage by the alkaline elution technique in liver, kidneys and lungs of rats and hamsters treated with N-nitrosodialkylamines. Carcinogenesis, 1983, Volume: 4, Issue:5 Topics: Animals; Carbon Tetrachloride; Cricetinae; Diethylnitrosamine; Dimethylnitrosamine; DNA; Kidney; Liver; Lung; Male; Mesocricetus; Nitrosamines; Rats; Tetraethylammonium Compounds	1983
Effect of indole on N-nitrosodimethylamine demethylase in rats treated with carbon tetrachloride. Food and cosmetics toxicology, 1981, Volume: 19, Issue:6 Topics: Animals; Body Weight; Carbon Tetrachloride; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Indoles; Liver; Male; Microsomes, Liver; Organ Size; Oxidoreductases, N-Demethylating; Rats; Time Factors	1981
Biochemical alterations in hepatic tissue of ethionine and N-nitrosodimethylamine treated mice, and in a transplantable tumor of rat. Drug and chemical toxicology, 1980, Volume: 3, Issue:1 Topics: Animals; Bromobenzenes; Carbon Tetrachloride; Dimethylnitrosamine; DNA; Ethionine; Female; Liver; Liver Neoplasms, Experimental; Male; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Neoplasm Transplantation; Rats; Time Factors; tRNA Methyltransferases	1980
Effects of dietary restriction on induction of unscheduled DNA synthesis (UDS) and replicative DNA synthesis (RDS) in rat liver. Mutation research, 1994, Volume: 322, Issue:4 Topics: Animals; Carbon Tetrachloride; Cells, Cultured; Dimethylnitrosamine; DNA Repair; DNA Replication; Energy Intake; Liver; Male; Microsomes, Liver; Organ Size; Rats; Rats, Inbred F344; S Phase	1994
Use of prostaglandin I2 analog in treatment of massive hepatic necrosis associated with endothelial cell injury and diffuse sinusoidal fibrin deposition. Digestive diseases and sciences, 1995, Volume: 40, Issue:1 Topics: Animals; Antithrombin III; Capillaries; Carbon Tetrachloride; Cells, Cultured; Dimethylnitrosamine; Endothelium, Vascular; Endotoxins; Epoprostenol; Fibrin; Liver; Liver Diseases; Male; Necrosis; Peptide Hydrolases; Portal Pressure; Propionibacterium acnes; Prothrombin Time; Rats; Rats, Inbred F344	1995
[Experimental study on changes of the pulmonary vessels in the cirrhotic rats]. Nihon Geka Gakkai zasshi, 1995, Volume: 96, Issue:1 Topics: Animals; Carbon Tetrachloride; Dimethylnitrosamine; Hemodynamics; Hypertension, Pulmonary; Liver Cirrhosis, Experimental; Liver Function Tests; Male; Mononuclear Phagocyte System; Pulmonary Artery; Rats; Rats, Wistar	1995
Preventive and therapeutic effects in rats of hepatocyte growth factor infusion on liver fibrosis/cirrhosis. Hepatology (Baltimore, Md.), 1997, Volume: 26, Issue:1 Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Body Weight; Carbon Tetrachloride; Dimethylnitrosamine; Fibrinogen; Hepatocyte Growth Factor; Humans; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Male; Organ Size; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Serum Albumin; Survival Rate	1997
Deleted form of hepatocyte growth factor (dHGF) increases the number of platelets in rats with liver cirrhosis. Liver, 1997, Volume: 17, Issue:4 Topics: Animals; Carbon Tetrachloride; Dimethylnitrosamine; Dose-Response Relationship, Drug; Hepatocyte Growth Factor; Liver; Liver Cirrhosis, Experimental; Male; Organ Size; Platelet Count; Prothrombin Time; Rats; Rats, Wistar; Spleen; Thrombocytopenia	1997
Effects of the deleted form of hepatocyte growth factor on serum hyaluronate levels in rats with liver cirrhosis. The Journal of veterinary medical science, 1998, Volume: 60, Issue:3 Topics: Animals; Carbon Tetrachloride; Dimethylnitrosamine; Hepatocyte Growth Factor; Humans; Hyaluronic Acid; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Liver Function Tests; Male; Organ Size; Prothrombin Time; Rats; Rats, Wistar; Recombinant Proteins; Sequence Deletion	1998
Transforming growth factor alpha levels in liver and blood correlate better than hepatocyte growth factor with hepatocyte proliferation during liver regeneration. The American journal of pathology, 1998, Volume: 153, Issue:3 Topics: Animals; Apoptosis; Carbon Tetrachloride; Cell Division; Dimethylnitrosamine; Disease Models, Animal; Hepatocyte Growth Factor; Liver; Liver Regeneration; Male; Mitotic Index; Necrosis; Phenobarbital; Rats; Rats, Sprague-Dawley; Transforming Growth Factor alpha	1998
Biphasic effect of colchicine on acute liver injury induced by carbon tetrachloride or by dimethylnitrosamine in mice. Journal of hepatology, 1999, Volume: 31, Issue:5 Topics: Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; bcl-X Protein; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Colchicine; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Lipid Peroxidation; Liver; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; Necrosis; Proto-Oncogene Proteins c-bcl-2	1999
Spleno-renal shunt blood flow is an accurate index of collateral circulation in different models of portal hypertension and after pharmacological changes in rats. Journal of hepatology, 2000, Volume: 32, Issue:3 Topics: Animals; Carbon Tetrachloride; Collateral Circulation; Dimethylnitrosamine; Disease Models, Animal; Hemodynamics; Hypertension, Portal; Ligation; Male; Octreotide; Portal Vein; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Reproducibility of Results; Somatostatin; Splenorenal Shunt, Surgical; Vasoconstrictor Agents	2000
Inhibition of hepatic stellate cell proliferation and activation by the semisynthetic analogue of fumagillin TNP-470 in rats. Hepatology (Baltimore, Md.), 2000, Volume: 32, Issue:5 Topics: Actins; Angiogenesis Inhibitors; Animals; Carbon Tetrachloride; Cell Division; Cells, Cultured; Cyclin-Dependent Kinases; Cyclins; Cyclohexanes; Dimethylnitrosamine; Liver; Liver Cirrhosis; Male; Muscle, Smooth; O-(Chloroacetylcarbamoyl)fumagillol; Platelet-Derived Growth Factor; Rats; Rats, Inbred F344; Receptor, Platelet-Derived Growth Factor beta; Sesquiterpenes	2000
Detection of unscheduled DNA synthesis in hepatocytes isolated from rats treated with genotoxic agents: an in vivo- in vitro assay for potential carcinogens and mutagens. Carcinogenesis, 1980, Volume: 1, Issue:7 Topics: 2-Acetylaminofluorene; Animals; Autoradiography; Carbon Tetrachloride; Carcinogens; Cell Nucleus; Cytoplasm; Dimethylnitrosamine; DNA; DNA Repair; Dose-Response Relationship, Drug; Hepatocytes; Kinetics; Male; Mutagens; Rats; Rats, Inbred F344; Thymidine; Tritium	1980
Antidiabetic thiazolidinediones inhibit collagen synthesis and hepatic stellate cell activation in vivo and in vitro. Gastroenterology, 2002, Volume: 122, Issue:7 Topics: Animals; Benzhydryl Compounds; Bile Ducts; Carbon Tetrachloride; Cell Division; Cells, Cultured; Collagen; Dimethylnitrosamine; DNA; Epoxy Compounds; Fibronectins; Hypoglycemic Agents; Ligation; Liver; Liver Cirrhosis; Male; Phenols; Pioglitazone; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors	2002
ANTIDOTAL EFFECT OF AMINOACETONITRILE AGAINST THE BIOCHEMICAL INJURY OF THE MICROSOMAL AMINO-ACID INCORPORATING SYSTEM INDUCED IN VIVO BY CARBON TETRACHLORIDE OR DIMETHYLNITROSAMINE. Biochemical and biophysical research communications, 1965, Feb-17, Volume: 18 Topics: Amino Acids; Aminoacetonitrile; Antidotes; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cyanides; Dimethylnitrosamine; Hepatitis; Leucine; Liver; Microsomes; Nitrosamines; Pharmacology; Rats; Research; Toxicology	1965
ENHANCEMENT OF THE POLYURIDYLIC ACID-DIRECTED PHENYLALANINE POLYMERIZATION IN LIVER-MICROSOME PREPARATIONS FROM RATS TREATED WITH CARBON TETRACHLORIDE OR DIMETHYLNITROSAMINE. Biochimica et biophysica acta, 1965, Apr-19, Volume: 95 Topics: Amino Acids; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; Hepatitis; Microsomes; Nitrosamines; Phenylalanine; Poly U; Polymerization; Polynucleotides; Rats; Research; Toxicology; Uracil Nucleotides	1965
Bone marrow-derived mesenchymal stem cells protect against experimental liver fibrosis in rats. World journal of gastroenterology, 2005, Jun-14, Volume: 11, Issue:22 Topics: Animals; Bone Marrow Cells; Carbon Tetrachloride; Cell Differentiation; Dimethylnitrosamine; Hematopoietic Stem Cell Transplantation; Hepatocytes; Liver Cirrhosis; Male; Mesoderm; Rats; Rats, Inbred F344	2005
Relationship between hepatic gene expression profiles and hepatotoxicity in five typical hepatotoxicant-administered rats. Toxicological sciences : an official journal of the Society of Toxicology, 2005, Volume: 87, Issue:1 Topics: Acetaminophen; Alkaline Phosphatase; Animals; Bromobenzenes; Carbon Tetrachloride; Dimethylnitrosamine; Gene Expression Profiling; L-Lactate Dehydrogenase; Liver; Male; Rats; Rats, Sprague-Dawley; Thioacetamide	2005
Sphingosine 1-phosphate regulates regeneration and fibrosis after liver injury via sphingosine 1-phosphate receptor 2. Journal of lipid research, 2009, Volume: 50, Issue:3 Topics: Animals; Carbon Tetrachloride; Dimethylnitrosamine; Female; Hepatocytes; Liver; Liver Cirrhosis; Liver Regeneration; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Proliferating Cell Nuclear Antigen; Receptors, Lysosphingolipid; Sphingosine; Sphingosine-1-Phosphate Receptors	2009
Kupffer cells are associated with apoptosis, inflammation and fibrotic effects in hepatic fibrosis in rats. Laboratory investigation; a journal of technical methods and pathology, 2010, Volume: 90, Issue:12 Topics: Animals; Apoptosis; Carbon Tetrachloride; Collagen Type I; Dimethylnitrosamine; Fibrosis; Hepatic Stellate Cells; Inflammation; Kupffer Cells; Lipopolysaccharides; Liver Cirrhosis; Male; Random Allocation; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha	2010
Liposomal oxymatrine in hepatic fibrosis treatment: formulation, in vitro and in vivo assessment. AAPS PharmSciTech, 2014, Volume: 15, Issue:3 Topics: Alkaloids; Animals; Carbon Tetrachloride; Chemistry, Pharmaceutical; Cytoprotection; Dimethylnitrosamine; Drug Carriers; Kinetics; Liposomes; Liver; Liver Cirrhosis, Experimental; Male; Mice, Inbred ICR; Protective Agents; Quinolizines; Solubility; Technology, Pharmaceutical; Vitamin E	2014
Two xanthones from Swertia punicea with hepatoprotective activities in vitro and in vivo. Journal of ethnopharmacology, 2014, May-14, Volume: 153, Issue:3 Topics: Acetaminophen; Animals; Aspartate Aminotransferases; Bilirubin; Carbon Tetrachloride; Cell Survival; Dimethylnitrosamine; Glutathione; Hep G2 Cells; Humans; L-Lactate Dehydrogenase; Liver; Liver Cirrhosis; Male; Malondialdehyde; Protective Agents; Rats, Wistar; Reactive Oxygen Species; Serum Albumin; Superoxide Dismutase; Swertia; Xanthones	2014
Comparison of TGF-β, PDGF, and CTGF in hepatic fibrosis models using DMN, CCl4, and TAA. Drug and chemical toxicology, 2016, Volume: 39, Issue:1 Topics: Animals; Carbon Tetrachloride; Connective Tissue Growth Factor; Dimethylnitrosamine; Disease Models, Animal; Immunohistochemistry; Lipid Peroxidation; Liver Cirrhosis, Experimental; Male; Platelet-Derived Growth Factor; Rats; Rats, Sprague-Dawley; Thioacetamide; Transforming Growth Factor beta	2016
Hepatoprotective effects of zingerone on carbon tetrachloride- and dimethylnitrosamine-induced liver injuries in rats. Archives of pharmacal research, 2016, Volume: 39, Issue:2 Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Antioxidants; Aspartate Aminotransferases; Biomarkers; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytoprotection; Dimethylnitrosamine; Guaiacol; Hep G2 Cells; Hepatic Stellate Cells; Humans; Hydroxyproline; Inflammation Mediators; Lipid Peroxidation; Liver; Liver Cirrhosis, Experimental; Male; Mitogen-Activated Protein Kinases; Oxidative Stress; Rats, Sprague-Dawley; Signal Transduction	2016