carbon tetrachloride has been researched along with curcumin in 51 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (1.96) | 18.2507 |
| 2000's | 13 (25.49) | 29.6817 |
| 2010's | 34 (66.67) | 24.3611 |
| 2020's | 3 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Kuttan, R; Soni, KB; Soudamini, KK; Unnikrishnan, MC | 1 |
| Jeon, CH; Kim, J; Ko, G; Park, EJ; Sohn, DH | 1 |
| Kamalakkannan, N; Menon, VP; Rajasekharan, KN; Rukkumani, R; Varma, PS; Viswanathan, P | 1 |
| Fang, L; He, YJ; Lü, X; Sheng, Y; Shu, JC | 1 |
| Moreno, MG; Muriel, P; Reyes-Gordillo, K; Segovia, J; Shibayama, M; Vergara, P | 1 |
| Fang, L; He, YJ; Lu, X; Shu, JC; Wang, HL; Ye, GR | 1 |
| Abu-Rizq, HA; Afzal, M; Mansour, MH; Safer, AM | 1 |
| Imura, T; Kitamoto, D; Oku, H; Takahashi, M; Takara, K; Wada, K | 1 |
| Chao, JC; Chu, CC; Lin, YH; Tsai, YH; Wu, SJ | 1 |
| Moreno, MG; Muriel, P; Reyes-Gordillo, K; Segovia, J; Shibayama, M; Tsutsumi, V; Vergara, P | 1 |
| Priya, S; Sudhakaran, PR | 1 |
| He, YJ; Lv, X; Shu, JC; Wang, LX; Ye, GR | 1 |
| Muriel, P; Rivera-Espinoza, Y | 1 |
| Chang, CC; Chao, JC; Tam, KW; Tsai, YH; Wu, SJ | 1 |
| Barik, A; Priyadarsini, KI; Singh, BG; Singh, U | 1 |
| Ao, Y; Bai, J; Gao, AM; Li, RW; Li, XH; Liu, L; Ping, J; Qin, HQ; Wang, H; Wei, XN | 1 |
| Abdalla, AM; Abdelwahab, SA; Mahmoud, AM; Mahmoud, ME; Morsy, MA | 1 |
| Chen, WX; Kong, DS; Lu, Y; Ma, J; Ni, CY; Ni, GX; Wang, AY; Zhang, F; Zhang, XJ; Zhang, XP; Zheng, SZ | 1 |
| Tu, CT; Wang, JY; Xu, BL; Yao, QY; Zhang, SC; Zhou, CH | 1 |
| Chen, WX; Kong, DS; Lu, Y; Ma, J; Ni, GX; Wang, AY; Zhang, F; Zhang, XP; Zhang, ZL; Zheng, SZ | 1 |
| Liu, HC; Tu, CT; Wang, JY; Xu, BL; Yao, QY; Zhang, SC | 1 |
| Al-Olayan, EM; Hassan, ZK | 1 |
| Chen, W; Guo, Y; Kong, D; Ni, W; Wang, Y; Zhang, S; Zhang, Y; Zhang, Z; Zheng, S | 1 |
| Chen, B; Dong, P; Gao, S; Guo, Y; Liao, Y; Lin, Z; Lu, Z; Shi, L; Wu, C; Yu, F; Zheng, J | 1 |
| Kakkar, V; Kaur, IP; Khullar, N; Singh, N | 1 |
| Chen, L; Kong, D; Lu, C; Lu, Y; Zhang, F; Zhang, X; Zhang, Z; Zheng, S | 1 |
| Abu-Rizq, HA; Afzal, M; Mansour, MH | 1 |
| Gong, M; He, X; Hu, Y; Li, R; Luo, S; Ma, X; Wang, J; Wang, R; Xiao, X; Zhang, P; Zhao, Y | 1 |
| Cao, L; Ding, W; Du, J; Jia, R; Liu, Y; Shen, Y; Yin, G; Zhao, C | 1 |
| Can, M; Hismiogullari, AA; Hismiogullari, SE; Karaca, O; Kus, I; Paksoy, S; Seyrek, K; Sunay, FB; Yavuz, O | 1 |
| Chen, DZ; Chen, RC; Chen, YP; Dong, JJ; Du, SJ; Feng, WK; Huang, SS; Liang, G; Wang, XD; Wu, H; Xu, LM; Yang, YP; Yu, ZP | 1 |
| Abdel Baky, NA; Al-Rasheed, NM; Ali, HM; El-Orabi, NF; Fadda, LM; Yacoub, HI | 1 |
| Ali, N; Chakraborty, S; Choudhury, ST; Das, N; Ghosh, D; Ghosh, S | 1 |
| Chen, J; Huang, R; Liu, Y; Pan, Z; Sun, Z; Wang, G; Wang, J; Wu, C; Wu, H; Xia, J; Xiong, Y; Yan, X; Zhang, Z | 1 |
| Chae, HJ; Choi, MK; Jung, HW; Kim, SW; Kim, YJ; Kwon, HJ; Lee, GH; Lee, HY | 1 |
| Bi, Q; Huang, L; Li, C; Li, Z; Liu, S; Shen, Q; Xie, J | 1 |
| Du, C; Feng, B; Lei, W; Pan, W; Wang, J; Wang, XJ; Wang, Y | 1 |
| Abdallah, HM; Abdel-Naim, AB; Ahmed, OAA; Al-Sawahli, MM; Algandaby, MM; Ashour, OM; Fahmy, UA; Hattori, M | 1 |
| Dai, C; Li, J; Liu, Q; Peng, X; Qiu, J | 1 |
| Khan, H; Nabavi, SM; Ullah, H | 1 |
| Hargrove, MW; Healy, JC; Martin, JS; Moore, AN; Phillips, CN; Pickich, MB; Roberts, MD | 1 |
| Abo-Zaid, MA; Ismail, AH; Shaheen, ES | 1 |
| Abbasnezhad, A; Abdolkarimi, B; Al-Jamal, HA; Alimoghaddam, K; Almanaitytė, M; An, C; Arro, J; Asmaa, MJS; Baek, SK; Bell, K; Bi, H; Bowman, DMJS; Boya, P; Bozorov, TA; Bressan, V; Burša, J; Cao, H; Cao, Y; Cecconi, F; Chahardouli, B; Chen, HH; Chen, J; Chen, L; Chen, Y; Choe, G; Choghakhori, R; Cousins, P; Cuenca, J; Ding, MX; Ding, Y; Du, H; El-Neanaey, WA; Fan, P; Fazeli Moghadam, E; Fei, Z; Fu, XY; Fuji, S; Ghadyani Nejad, L; Ghahremani, MH; Ghaleb, AM; Ghallab, OM; Grus, F; Gu, X; Guo, C; Gutierrez, B; Habibi, M; Hahn, MA; Han, D; Han, JJ; Hassan, R; Hayati, A; Hayter, M; He, P; Higeno, A; Hino, A; Ho, HL; Hong, SK; Huang, H; Hussain, FA; Hussein, AR; Hwang, SI; Idota, A; Ishikawa, J; Javadzadeh Shahshahani, H; Jiang, J; Jiang, L; Jiang, Y; Johan, MF; Jurevičius, J; Kang, Y; Kim, HJ; Kim, JK; Kim, SY; Koike, M; Kuang, X; Lee, HJ; Li, DX; Li, H; Li, L; Li, S; Li, Y; Liang, Z; Liu, C; Liu, H; Liu, J; Liu, L; Liu, X; Lokaj, P; Londo, J; Long, C; Lu, Y; Luo, G; Ma, X; Mačianskienė, R; Maeng, CH; Mao, Y; Masaie, H; Min, S; Mohamed Abu-Shelou, S; Mohammadi, S; Moudr, J; Mousavi, SA; Mu, H; Naemi, R; Nakata, K; Nekoohesh, L; Nguyen, HC; Nguyen, TL; Nikbakht, M; Ning, J; Niu, ML; Oka, C; Palese, A; Pan, XM; Park, TS; Pásek, M; Pham, DC; Ragab, AE; Ramadan, MZ; Riyaphan, J; Rodriguez-Muela, N; Rosignol, I; Rostami, S; Ryffel, B; Salumbides, EJ; Schmelter, C; Shamsuddin, S; Sharp, BR; Shen, H; Shen, Y; Sierra-Filardi, E; Sun, C; Sun, H; Swelem, RS; Tada, Y; Tang, H; Tao, W; Togbe, D; Trinh, TK; Trivikram, TM; Ubachs, W; Vaezi, M; Vaverka, J; Von Elert, E; Wang, B; Wang, H; Wang, N; Wang, R; Wang, X; Wang, Y; Wang, Z; Watson, R; Wcisło, P; Wen, XJ; Weng, CF; Wollin, L; Wu, LL; Wu, W; Xi, J; Xi, X; Xia, B; Xiong, JH; Xu, B; Xu, Y; Yahaya, BH; Yamasaki, T; Yan, B; Yan, J; Yang, J; Yang, R; Yang, Y; Yao, J; Yin, L; Yoshida, H; Yu, J; Yu, S; Yuan, Y; Zare, S; Zhang, DY; Zhang, H; Zhang, M; Zhang, P; Zhang, Q; Zhang, W; Zhang, WS; Zhang, X; Zhang, Y; Zhong, GY; Zhong, H; Zhou, P; Zhou, Q; Zhou, X; Zhou, Z; Zhu, H | 1 |
| Al-Tamimi, J; Alhazza, IM; Ebaid, H; Habila, M; Hassan, I; Omar, MS; Rady, A | 1 |
| Hou, XH; Qian, W; Wang, JP; Xu, KS; Yang, L | 1 |
| Bilehal, D; Kim, HK; Kim, YH; Lee, DS; Lee, HS; Li, L; Li, W | 1 |
| Gao, J; Hu, S; Liu, J; Xie, J; Yang, L; Zhang, Z | 1 |
| Chakraborty, B; Sengupta, M; Sharma, GD | 1 |
| Jun, W; Kim, JC; Kim, K; Kim, MS; Kim, Y; Lee, J; Lee, YH; Yoon, HG; You, Y | 1 |
| Devaraj, S; Ismail, S; Ramanathan, S; Yam, MF | 1 |
| Agu, CE; Chukwu, IJ; Nnedu, EB; Uchendu, IK | 1 |
3 review(s) available for carbon tetrachloride and curcumin
| Article | Year |
|---|---|
Pharmacological actions of curcumin in liver diseases or damage.
Topics: Animals; Carbon Tetrachloride; Cholestasis; Curcuma; Curcumin; Humans; Iron; Liver; Liver Cirrhosis; Liver Cirrhosis, Biliary; Liver Diseases; Thioacetamide | 2009 |
Mechanistic insights of hepatoprotective effects of curcumin: Therapeutic updates and future prospects.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Curcumin; Diethylnitrosamine; Hexachlorocyclohexane; Humans; Liver; Metals, Heavy; Oxidative Stress; Protective Agents | 2019 |
Topics: Action Potentials; Adolescent; Adult; Aged; Alanine Transaminase; Analgesics; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Apoptosis; Arrhythmias, Cardiac; Atrial Fibrillation; Biological Transport; Biomarkers; Blood Gas Analysis; Blood-Brain Barrier; Blotting, Western; Bone and Bones; Bone Marrow; Bone Neoplasms; Brain; Breast Neoplasms; Calcium; Carbon Tetrachloride; Cartilage, Articular; Case-Control Studies; CD59 Antigens; CDC2 Protein Kinase; Celastrus; Cell Cycle; Cell Division; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chemical Fractionation; Colitis, Ulcerative; Colon; Computer Simulation; Curcumin; Cyclin B1; Cymenes; Cytokines; Dextran Sulfate; Dipeptidyl Peptidase 4; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Ectodysplasins; Electroencephalography; Endothelial Cells; Epithelial Cells; Epithelial-Mesenchymal Transition; Exosomes; Female; Flavonoids; G2 Phase; Gene Expression Regulation; Glial Cell Line-Derived Neurotrophic Factor; Heart Atria; Heart Conduction System; Heart Ventricles; HeLa Cells; Hemodynamics; Humans; Image Interpretation, Computer-Assisted; Indoles; Inflammation; Interleukin-1beta; Interleukin-6; Iridoid Glycosides; Ki-1 Antigen; Lens, Crystalline; Lifting; Liver; Liver Cirrhosis; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Microelectrodes; Middle Aged; Models, Cardiovascular; Multiparametric Magnetic Resonance Imaging; Myeloid Differentiation Factor 88; NADPH Oxidase 1; Neoplasm Grading; NF-kappa B; Osteoarthritis; Osteoblasts; Osteoclasts; Oxidative Stress; Oxygen; Patch-Clamp Techniques; PC-3 Cells; Permeability; Peroxidase; Plant Extracts; Plant Leaves; Prostate; Prostatic Neoplasms; Protective Agents; Proto-Oncogene Proteins c-akt; Psychophysics; Purpura, Thrombocytopenic, Idiopathic; Rabbits; Rats; Rats, Sprague-Dawley; Recovery of Function; Retrospective Studies; RNA, Long Noncoding; ROC Curve; Safety; Shoes; Signal Transduction; Sodium; Sonication; Spinal Cord; Spinal Cord Injuries; Syringa; Tight Junctions; Tissue Inhibitor of Metalloproteinase-1; Toll-Like Receptor 2; Transforming Growth Factor beta2; Transient Receptor Potential Channels; Tumor Microenvironment; Tumor Necrosis Factor-alpha; Umbilical Cord; Up-Regulation; Ventricular Function; Young Adult | 2016 |
1 trial(s) available for carbon tetrachloride and curcumin
| Article | Year |
|---|---|
Effects of curcumin on antioxidative activities and cytokine production in Jian carp (Cyprinus carpio var. Jian) with CCl4-induced liver damage.
Topics: Animals; Carbon Tetrachloride; Carps; Curcumin; Cytokines; Fish Proteins; Gene Expression Regulation; Liver; RNA, Messenger; Tumor Necrosis Factor-alpha | 2015 |
47 other study(ies) available for carbon tetrachloride and curcumin
| Article | Year |
|---|---|
Inhibition of lipid peroxidation and cholesterol levels in mice by curcumin.
Topics: Animals; Carbon Tetrachloride; Cholesterol; Curcumin; Cyclophosphamide; Lipid Peroxidation; Lipid Peroxides; Male; Mice; Paraquat | 1992 |
Protective effect of curcumin in rat liver injury induced by carbon tetrachloride.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Curcumin; Dose-Response Relationship, Drug; Hydroxyproline; Liver; Liver Diseases; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley | 2000 |
Comparative effects of curcumin and an analogue of curcumin in carbon tetrachloride-induced hepatotoxicity in rats.
Topics: Animals; Carbon Tetrachloride; Curcumin; Diarylheptanoids; Free Radicals; Glutathione; Lipid Peroxidation; Liver; Male; Rats; Rats, Wistar | 2005 |
[Prophylactic effect of curcumin on hepatic fibrosis and its relationship with activated hepatic stellate cells].
Topics: Animals; Apoptosis; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Curcumin; Enzyme Inhibitors; Hepatocytes; Liver Cirrhosis, Experimental; Rats; Rats, Sprague-Dawley | 2006 |
Curcumin protects against acute liver damage in the rat by inhibiting NF-kappaB, proinflammatory cytokines production and oxidative stress.
Topics: Active Transport, Cell Nucleus; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Biomarkers; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cell Nucleus; Cholestasis; Curcumin; Cytokines; Inflammation Mediators; Liver; Male; Necrosis; NF-kappa B; Oxidative Stress; Rats; Rats, Wistar | 2007 |
[The study of therapeutic effects of curcumin on hepatic fibrosis and variation of correlated cytokine].
Topics: Alanine Transaminase; Animals; Becaplermin; Carbon Tetrachloride; Curcumin; Cytokines; Drugs, Chinese Herbal; Hyaluronic Acid; Liver Cirrhosis, Experimental; Male; Phytotherapy; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Rats; Rats, Sprague-Dawley; Salvia miltiorrhiza; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha | 2007 |
Cyto-protective and immunomodulating effect of Curcuma longa in Wistar rats subjected to carbon tetrachloride-induced oxidative stress.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Curcuma; Curcumin; Cytoprotection; Hepatocytes; Immunity; Immunologic Factors; Liver; Oxidative Stress; Plant Extracts; Rats; Rats, Wistar; T-Lymphocytes | 2008 |
Characterization and bioavailability of liposomes containing a ukon extract.
Topics: Biological Availability; Carbon Tetrachloride; Curcuma; Curcumin; Gastric Juice; Intestines; Liposomes; Liver; Particle Size; Plant Extracts | 2008 |
Curcumin or saikosaponin a improves hepatic antioxidant capacity and protects against CCl4-induced liver injury in rats.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Curcumin; Glutathione; Lipids; Liver; Liver Diseases; Male; Oleanolic Acid; Rats; Rats, Sprague-Dawley; Saponins; Superoxide Dismutase | 2008 |
Curcumin prevents and reverses cirrhosis induced by bile duct obstruction or CCl4 in rats: role of TGF-beta modulation and oxidative stress.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cholestasis; Curcumin; Dose-Response Relationship, Drug; Drug Interactions; Liver Cirrhosis, Experimental; Male; Oxidative Stress; Rats; Rats, Wistar; Transforming Growth Factor beta | 2008 |
Curcumin-induced recovery from hepatic injury involves induction of apoptosis of activated hepatic stellate cells.
Topics: Animals; Apoptosis; Biomarkers; Carbon Tetrachloride; Curcumin; Liver; Male; Rats; Rats, Sprague-Dawley | 2008 |
Curcumin prevents liver fibrosis by inducing apoptosis and suppressing activation of hepatic stellate cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Carbon Tetrachloride; Curcumin; Hepatic Stellate Cells; In Situ Nick-End Labeling; Lipid Peroxidation; Liver Cirrhosis; Male; Rats; Rats, Sprague-Dawley | 2009 |
Curcumin and saikosaponin a inhibit chemical-induced liver inflammation and fibrosis in rats.
Topics: Animals; Anti-Inflammatory Agents; Bupleurum; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Collagen; Curcuma; Curcumin; Cytokines; Dietary Supplements; Drug Therapy, Combination; Fibrosis; Hydroxyproline; Inflammation; Liver; Male; NF-kappa B; Oleanolic Acid; Phytotherapy; Plant Extracts; Plant Roots; Random Allocation; Rats; Rats, Sprague-Dawley; Rhizome; Saponins; Transforming Growth Factor beta1 | 2010 |
Reactions of reactive oxygen species (ROS) with curcumin analogues: Structure-activity relationship.
Topics: Biphenyl Compounds; Carbon Tetrachloride; Curcumin; Diarylheptanoids; Free Radical Scavengers; Free Radicals; Hydroxyl Radical; Peroxides; Picrates; Pulse Radiolysis; Reactive Oxygen Species; Singlet Oxygen; Spectrum Analysis; Structure-Activity Relationship; Superoxides | 2011 |
Indole-3-carbinol enhances the resolution of rat liver fibrosis and stimulates hepatic stellate cell apoptosis by blocking the inhibitor of κB kinase α/inhibitor of κB-α/nuclear factor-κB pathway.
Topics: Animals; Apoptosis; Bile Ducts; Carbon Tetrachloride; Curcumin; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Hepatic Stellate Cells; I-kappa B Kinase; I-kappa B Proteins; Indoles; Liver; Liver Cirrhosis; Male; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Protein Array Analysis; Rats; Rats, Wistar; Signal Transduction; Solvents; Swine; Transfection | 2011 |
Protective effects of curcumin, α-lipoic acid, and N-acetylcysteine against carbon tetrachloride-induced liver fibrosis in rats.
Topics: Acetylcysteine; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Bilirubin; Carbon Tetrachloride; Curcumin; gamma-Glutamyltransferase; Glutathione; Liver Cirrhosis; Male; Malondialdehyde; Matrix Metalloproteinase 13; Rats; Rats, Wistar; Thioctic Acid; Transforming Growth Factor alpha | 2012 |
Acupuncture combined with curcumin attenuates carbon tetrachloride-induced hepatic fibrosis in rats.
Topics: Acupuncture Therapy; Animals; Carbon Tetrachloride; Combined Modality Therapy; Curcumin; Extracellular Matrix; Humans; Liver Cirrhosis; Male; Random Allocation; Rats; Rats, Sprague-Dawley | 2012 |
Protective effects of curcumin against hepatic fibrosis induced by carbon tetrachloride: modulation of high-mobility group box 1, Toll-like receptor 4 and 2 expression.
Topics: Animals; Base Sequence; Carbon Tetrachloride; Curcumin; DNA Primers; HMGB1 Protein; Liver Cirrhosis; Male; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Toll-Like Receptor 2; Toll-Like Receptor 4 | 2012 |
Acupuncture combined with curcumin disrupts platelet-derived growth factor β receptor/extracellular signal-regulated kinase signalling and stimulates extracellular matrix degradation in carbon tetrachloride-induced hepatic fibrosis in rats.
Topics: Acupuncture Therapy; Animals; Carbon Tetrachloride; Combined Modality Therapy; Curcumin; Extracellular Matrix; Extracellular Signal-Regulated MAP Kinases; Humans; Liver Cirrhosis; Male; Rats; Rats, Sprague-Dawley; Receptor, Platelet-Derived Growth Factor beta; Signal Transduction | 2012 |
Inhibition by curcumin of multiple sites of the transforming growth factor-beta1 signalling pathway ameliorates the progression of liver fibrosis induced by carbon tetrachloride in rats.
Topics: Animals; Carbon Tetrachloride; Curcuma; Curcumin; Disease Progression; Down-Regulation; Humans; Liver Cirrhosis; Male; Phosphorylation; Plant Extracts; Rats; Rats, Sprague-Dawley; Signal Transduction; Smad Proteins; Transforming Growth Factor beta1 | 2012 |
Curcumin reorganizes miRNA expression in a mouse model of liver fibrosis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbon Tetrachloride; Curcumin; Disease Models, Animal; Gene Expression Regulation; Liver Cirrhosis; Mice; MicroRNAs; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2012 |
Curcumin modulates cannabinoid receptors in liver fibrosis in vivo and inhibits extracellular matrix expression in hepatic stellate cells by suppressing cannabinoid receptor type-1 in vitro.
Topics: Animals; Carbon Tetrachloride; Curcumin; Extracellular Matrix; Extracellular Matrix Proteins; Gene Expression Regulation; Hepatic Stellate Cells; Liver Cirrhosis; Male; Models, Molecular; Protein Conformation; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1 | 2013 |
Curcumin up-regulates phosphatase and tensin homologue deleted on chromosome 10 through microRNA-mediated control of DNA methylation--a novel mechanism suppressing liver fibrosis.
Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Carbon Tetrachloride; Cell Proliferation; Cells, Cultured; Chromosome Deletion; Chromosomes, Human, Pair 10; Curcumin; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; Gene Expression Regulation; Hepatic Stellate Cells; Humans; Liver Cirrhosis; Luciferases; Male; MicroRNAs; Promoter Regions, Genetic; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering | 2014 |
Attenuation of carbon tetrachloride-induced hepatic injury with curcumin-loaded solid lipid nanoparticles.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Carbon Tetrachloride; Curcumin; Glutathione; Lipids; Liver; Liver Diseases; Male; Malondialdehyde; Nanoparticles; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2014 |
Curcumin attenuates angiogenesis in liver fibrosis and inhibits angiogenic properties of hepatic stellate cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Carbon Tetrachloride; Cell Proliferation; Cells, Cultured; Curcumin; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Hepatic Stellate Cells; Liver Cirrhosis; Male; Neovascularization, Pathologic; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Xenograft Model Antitumor Assays | 2014 |
Curcuma longa attenuates carbon tetrachloride-induced oxidative stress in T-lymphocyte subpopulations.
Topics: Animals; Antigens, CD; Carbon Tetrachloride; Cell Proliferation; Cell Survival; Curcuma; Curcumin; Interleukin-2 Receptor alpha Subunit; Male; Oxidative Stress; Plant Extracts; Rats, Wistar; Receptors, Cell Surface; Receptors, Transferrin; T-Lymphocyte Subsets; Thymocytes | 2015 |
Curcumin protects against CCl4-induced liver fibrosis in rats by inhibiting HIF-1α through an ERK-dependent pathway.
Topics: Animals; Carbon Tetrachloride; Cell Proliferation; Curcumin; Hypoxia-Inducible Factor 1, alpha Subunit; Liver; Liver Cirrhosis; Liver Function Tests; Male; MAP Kinase Signaling System; Protective Agents; Rats; Rats, Sprague-Dawley; Signal Transduction | 2014 |
The protective effect of curcumin administration on carbon tetrachloride (CCl4)-induced nephrotoxicity in rats.
Topics: Acute Kidney Injury; Animals; Antioxidants; Carbon Tetrachloride; Curcumin; Kidney; Male; Protective Agents; Rats; Rats, Wistar | 2015 |
Cannabinoid receptors are involved in the protective effect of a novel curcumin derivative C66 against CCl4-induced liver fibrosis.
Topics: Animals; Carbon Tetrachloride; Curcumin; Cytoprotection; Gene Expression Regulation; Hepatic Stellate Cells; JNK Mitogen-Activated Protein Kinases; Liver; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Protein Transport; Receptors, Cannabinoid; Signal Transduction | 2016 |
New mechanism in the modulation of carbon tetrachloride hepatotoxicity in rats using different natural antioxidants.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Curcumin; Drug Therapy, Combination; Liver; Liver Cirrhosis, Experimental; Liver Function Tests; Male; Rats, Sprague-Dawley; Silymarin; Vitamin E | 2016 |
Vesicular (liposomal and nanoparticulated) delivery of curcumin: a comparative study on carbon tetrachloride-mediated oxidative hepatocellular damage in rat model.
Topics: Animals; Antioxidants; Apoptosis; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Curcumin; Disease Models, Animal; Drug Delivery Systems; Female; Hepatocytes; Liposomes; Liver; Mitochondria; Nanoparticles; Necrosis; Oxidative Stress; Rats; Reactive Oxygen Species | 2016 |
Curcumin protects against liver fibrosis by attenuating infiltration of Gr1hi monocytes through inhibition of monocyte chemoattractant protein-1.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens, Ly; Carbon Tetrachloride; Chemokine CCL2; Curcumin; Disease Models, Animal; Flow Cytometry; Humans; Immunohistochemistry; Inflammation; Liver; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Monocytes; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha | 2016 |
Turmeric extract and its active compound, curcumin, protect against chronic CCl4-induced liver damage by enhancing antioxidation.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Curcuma; Curcumin; Glutathione; Lipid Peroxidation; Lipids; Liver; Male; Oxidative Stress; Plant Extracts; Protective Agents; Rats; Rats, Sprague-Dawley; Reproducibility of Results | 2016 |
Highly Selective Targeting of Hepatic Stellate Cells for Liver Fibrosis Treatment Using a d-Enantiomeric Peptide Ligand of Fn14 Identified by Mirror-Image mRNA Display.
Topics: Animals; Carbon Tetrachloride; Cell Line; Curcumin; Endocytosis; Hepatic Stellate Cells; Humans; Liposomes; Liver; Liver Cirrhosis; Male; Mice; Peptides; RNA, Messenger; TWEAK Receptor | 2017 |
Enhanced efficacy of curcumin with phosphatidylserine-decorated nanoparticles in the treatment of hepatic fibrosis.
Topics: Animals; Carbon Tetrachloride; Curcumin; Hepatocyte Growth Factor; Liver; Liver Cirrhosis; Macrophages; Male; Matrix Metalloproteinases; Nanoparticles; Nanostructures; Phosphatidylserines; Rats; Rats, Sprague-Dawley | 2018 |
Curcumin-Zein Nanospheres Improve Liver Targeting and Antifibrotic Activity of Curcumin in Carbon Tetrachloride-Induced Mice Liver Fibrosis.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Curcumin; Drug Delivery Systems; Liver; Liver Cirrhosis; Male; Mice; Nanospheres; Oxidative Stress; Zein | 2016 |
Curcumin Attenuates on Carbon Tetrachloride-Induced Acute Liver Injury in Mice via Modulation of the Nrf2/HO-1 and TGF-β1/Smad3 Pathway.
Topics: Animals; Carbon Tetrachloride; Caspase 3; Caspase 9; Chemical and Drug Induced Liver Injury; Curcumin; Cytokines; Disease Models, Animal; Gene Expression Regulation; Heme Oxygenase-1; Liver Function Tests; Male; Mice; NF-E2-Related Factor 2; Oxidative Stress; Protective Agents; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta1 | 2018 |
Effect of curcumin supplementation on serum expression of select cytokines and chemokines in a female rat model of nonalcoholic steatohepatitis.
Topics: Animals; Anti-Inflammatory Agents; Carbon Tetrachloride; Chemokine CCL5; Chemokine CX3CL1; Curcumin; Diet, Western; Dietary Supplements; Disease Models, Animal; Drug Administration Schedule; Female; Gene Expression Regulation; Humans; Interleukin-13; Interleukin-17; Interleukin-2; Liver; Non-alcoholic Fatty Liver Disease; Rats; Rats, Wistar; Treatment Outcome | 2019 |
Immunomodulatory effect of curcumin on hepatic cirrhosis in experimental rats.
Topics: Animals; Carbon Tetrachloride; Curcumin; Immunity; Liver Cirrhosis; Rats | 2020 |
Curcumin-containing Silver Nanoparticles Prevent Carbon Tetrachloride- induced Hepatotoxicity in Mice.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Curcumin; Liver; Male; Metal Nanoparticles; Mice; Mice, Inbred C57BL; Silver | 2021 |
[Effects of extracts of Rhizoma curcumae on angiotensin II and its type 1 receptor expression in rat liver fibrosis induced by CCl4].
Topics: Angiotensin II; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Curcuma; Drugs, Chinese Herbal; Liver Cirrhosis, Experimental; Male; Phytotherapy; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1 | 2006 |
The protective effects of Curcuma longa Linn. extract on carbon tetrachloride-induced hepatotoxicity in rats via upregulation of Nrf2.
Topics: Animals; Carbon Tetrachloride; Curcuma; Cytoprotection; Injections, Intraperitoneal; Liver; Male; NF-E2-Related Factor 2; Plant Extracts; Rats; Rats, Sprague-Dawley; Up-Regulation | 2010 |
Downregulation effects of beta-elemene on the levels of plasma endotoxin, serum TNF-alpha, and hepatic CD14 expression in rats with liver fibrosis.
Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; China; Curcuma; Disease Models, Animal; Down-Regulation; Endotoxins; Injections, Intraperitoneal; Lipopolysaccharide Receptors; Liver; Liver Cirrhosis; Male; Plant Preparations; Rats; Rats, Wistar; Sesquiterpenes; Tumor Necrosis Factor-alpha | 2011 |
Hepatoprotective and immunomodulatory properties of aqueous extract of Curcuma longa in carbon tetra chloride intoxicated Swiss albino mice.
Topics: Animals; Aspartate Aminotransferases; Bilirubin; Carbon Tetrachloride; Cell Adhesion; Curcuma; Cytotoxicity, Immunologic; Immunologic Factors; Liver; Macrophages, Peritoneal; Male; Mice; Nitric Oxide; Peroxidase; Plant Extracts; Protective Agents | 2011 |
Hepatoprotective effects of fermented Curcuma longa L. on carbon tetrachloride-induced oxidative stress in rats.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Curcuma; Fermentation; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley | 2014 |
Investigation of antioxidant and hepatoprotective activity of standardized Curcuma xanthorrhiza rhizome in carbon tetrachloride-induced hepatic damaged rats.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Curcuma; Hexanes; Lipid Peroxidation; Liver; Male; Plant Extracts; Rats; Rats, Sprague-Dawley; Rhizome | 2014 |
Combination of aqueous extracts of Curcuma longa (turmeric) and some calcium channel blockers synergistically improves CCl4-induced nephrotoxicity in albino rats.
Topics: Acute Kidney Injury; Amlodipine; Animals; Antioxidants; Calcium Channel Blockers; Carbon Tetrachloride; Curcuma; Disease Models, Animal; Drug Synergism; Kidney; Male; Mice; Nifedipine; Oxidative Stress; Plant Extracts; Rats, Wistar | 2020 |