carbon tetrachloride has been researched along with beta-escin in 39 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.56) | 18.7374 |
| 1990's | 10 (25.64) | 18.2507 |
| 2000's | 8 (20.51) | 29.6817 |
| 2010's | 18 (46.15) | 24.3611 |
| 2020's | 2 (5.13) | 2.80 |
| Authors | Studies |
|---|---|
| Brixová, E; Cizová, M; Ulicná, O; Valachová, A | 1 |
| Ding, Y; Huang, DK; Shen, JP; Zhang, XL; Zhang, YD; Zhu, SH | 1 |
| Chuang, CH; Lin, CC; Liu, SY; Yen, MH | 1 |
| Cui, JC; Liu, AJ; Wang, BX | 1 |
| Deltour, P; Fernandez, Y; Fernandez-Lopez, JA; Mitjavila, S; Periquet, A; Subirade, I | 1 |
| Choi, KJ; Kim, SC; Lee, JH; Park, HJ; Park, KH; Park, KM; Rhee, MH; Song, YB | 1 |
| Chun, YJ; Jeong, TC; Kim, HJ; Kim, SI; Park, JD; Roh, JK | 1 |
| Itoh, N; Kimura, T; Kitagawa, I; Kobayashi, M; Muto, N; Nakanishi, H; Tanaka, K | 1 |
| Arao, T; Kinjo, J; Miyao, H; Nohara, T; Udayama, M | 1 |
| Jeong, HG; Park, HY | 1 |
| Chen, HH; Chen, JC; Chen, LD; Tsai, CC; Wang, WC | 1 |
| Sun, H; Tao, S; Wang, Y; Zhao, Y | 1 |
| Baiuomy, AR; El-Sayed, MM; Marzouk, MS; Mohamed, MA; Moharram, FA | 1 |
| Arun, M; Asha, VV | 1 |
| Cheng, YA; Dang, SS; Li, ZF; Liu, ZG; Song, P; Wang, BF | 1 |
| Chao, JC; Chu, CC; Lin, YH; Tsai, YH; Wu, SJ | 1 |
| Achudume, AC; Ogunyemi, KE | 1 |
| Chen, LJ; Dai, LL; He, CM; Huang, CQ; Peng, XD; Yang, B | 1 |
| Jew, SS; Kim, SH; Kim, YC; Lee, ES; Lee, MK; Lim, DY; Park, HG; Ryu, JH; Sung, SH; Yang, H | 1 |
| Chang, CC; Chao, JC; Tam, KW; Tsai, YH; Wu, SJ | 1 |
| Kondeva-Burdina, MS; Krasteva, IN; Mitcheva, MK; Nikolov, SD; Simeonova, RL; Vitcheva, VB | 1 |
| Guo, ML; Lou, Z; Wang, Y; Wu, QB | 1 |
| He, M; Huang, Q; Huang, R; Lin, X; Zhang, S; Zheng, L | 1 |
| Krasteva, I; Mitcheva, M; Nikolov, S; Simeonova, R; Vitcheva, V | 1 |
| Dong, D; Han, X; Peng, J; Qi, Y; Tang, X; Xu, Y; Yin, L; Zhang, S | 1 |
| Jiang, H; Liu, XC; Wang, YZ; Xue, X | 1 |
| Han, X; Liu, K; Peng, J; Qi, Y; Xu, L; Xu, Y; Yin, L; Yu, H; Zheng, L | 1 |
| Chen, Y; Huang, L; Li, J; Miao, Y; Sun, H; Yang, J; Zhao, Y; Zhou, W | 1 |
| Fang, H; Qiu, X; Sun, Y; Wang, J; Wang, X; Wang, Z; Xia, Z; Zhang, F | 1 |
| Al-Dosari, MS; Al-Rehaily, AJ; Al-Sohaibani, M; AlSaid, MS; Arbab, AH; Parvez, MK; Rafatullah, S; Zaroug, EE | 1 |
| Dong, D; Peng, J; Qi, Y; Xu, L; Yin, L | 1 |
| He, Q; Lei, F; Lei, X; Li, R; Tan, H | 1 |
| Li, Q; Wang, Z; Wei, D; Wen, Z; Xiang, M; Zhang, F; Zhou, Y | 1 |
| Bian, M; Chen, A; Chen, X; Jin, H; Shao, J; Wang, F; Zhang, C; Zhang, F; Zheng, S | 1 |
| Chen, Y; Li, Y; Lin, L; Que, R; Shen, Y; Yan, N | 1 |
| Chen, J; Jiang, X; Sui, M; Yang, H; Zhu, Y | 1 |
| Bian, H; Li, L; Li, Q; Qi, J; Xu, J; Zhou, J | 1 |
| Chen, Y; Li, Y; Lin, L; Liu, X; Que, R; Shi, Z; Zhang, K; Zhou, M | 1 |
| Chen, Y; Li, Y; Lin, L; Que, R; Zhang, N; Zhou, M | 1 |
39 other study(ies) available for carbon tetrachloride and beta-escin
| Article | Year |
|---|---|
[The effect of beta-escin on metabolism in experimental liver steatosis in rats].
Topics: Animals; Blood Glucose; Carbon Tetrachloride; Escin; Fatty Liver; Glycogen; Hydrazines; Lipid Metabolism; Male; Rats; Rats, Wistar | 1994 |
[Effects of astragalus (ASI, SK) on experimental liver injury].
Topics: Acetaminophen; Alanine Transaminase; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Galactosamine; Glucosides; Glutathione; Male; Malondialdehyde; Mice; Microsomes, Liver; Rats; Saponins; Triterpenes | 1992 |
Evaluation of root quality of Bupleurum species by TLC scanner and the liver protective effects of "xiao-chai-hu-tang" prepared using three different Bupleurum species.
Topics: Animals; Calibration; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chromatography, Thin Layer; Drugs, Chinese Herbal; Liver; Liver Diseases; Male; Oleanolic Acid; Plant Extracts; Rats; Rats, Inbred Strains; Sapogenins; Saponins | 1991 |
[The effect of saponin isolated from stems and leaves of ginseng on experimental liver injury].
Topics: Animals; Carbon Tetrachloride; Fatty Liver; Liver; Male; Mice; Mice, Inbred Strains; Panax; Plants, Medicinal; Rats; Saponins; Sulfobromophthalein; Thioacetamide | 1983 |
Ca-efflux, from direct membrane injury by CCl4, is elicited by amphiphilic vehicles in vitro.
Topics: Animals; Calcium; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Electron Spin Resonance Spectroscopy; Ethanol; Homeostasis; Intracellular Membranes; Liver; Liver Diseases; Male; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Saponins; Solvents | 1993 |
Effect of ginsenoside Rb1 on rat liver phosphoproteins induced by carbon tetrachloride.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Carbon Tetrachloride; Ginsenosides; Glycogen; Liver; Male; Microsomes, Liver; Molecular Weight; Panax; Phosphoproteins; Phosphorylation; Plants, Medicinal; Protein Kinase C; Rats; Rats, Wistar; Saponins; Sulfonamides | 1996 |
Protection of rat liver microsomes against carbon tetrachloride-induced lipid peroxidation by red ginseng saponin through cytochrome P450 inhibition.
Topics: Animals; Carbon Tetrachloride; Cytochrome P-450 CYP2E1 Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Kinetics; Lipid Peroxidation; Male; Microsomes, Liver; NADP; Panax; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Saponins | 1997 |
Metallothionein-independent hepatoprotection by zinc and sakuraso-saponin.
Topics: Animals; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Liver; Male; Metallothionein; Mice; Mice, Inbred Strains; Saponins; Transaminases; Zinc | 1997 |
Kaikasaponin III and soyasaponin I, major triterpene saponins of Abrus cantoniensis, act on GOT and GPT: influence on transaminase elevation of rat liver cells concomitantly exposed to CCl4 for one hour.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbohydrate Sequence; Carbon Tetrachloride; Liver; Male; Medicine, Chinese Traditional; Molecular Sequence Data; Oleanolic Acid; Plants, Medicinal; Rats; Rats, Wistar; Saponins | 1998 |
The prevention of carbon tetrachloride-induced hepatotoxicity in mice by alpha-hederin: inhibiton of cytochrome P450 2E1 expression.
Topics: Animals; Carbon Tetrachloride; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Drugs, Chinese Herbal; Injections, Intraperitoneal; Injections, Subcutaneous; Liver; Male; Mice; Mice, Inbred BALB C; Microsomes, Liver; Oleanolic Acid; Saponins | 1998 |
Therapeutic effect of gypenoside on chronic liver injury and fibrosis induced by CCl4 in rats.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury, Chronic; Disease Models, Animal; Drugs, Chinese Herbal; Hypolipidemic Agents; Liver Cirrhosis, Experimental; Male; Poisons; Rats; Rats, Wistar; Saponins | 2000 |
[The further studies on the pharmacological actions of Bupleurum smithii var. parvifolium].
Topics: Analgesics; Animals; Bupleurum; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Drugs, Chinese Herbal; Female; Immunoglobulin G; Liver; Liver Diseases; Male; Mice; Phytotherapy; Saponins | 1998 |
Phytochemical constituents and hepatoprotective activity of Viburnum tinus.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Drug Evaluation, Preclinical; Iridoids; Lipid Peroxides; Liver; Male; Molecular Structure; Nitric Oxide; Oleanolic Acid; Plant Extracts; Plants, Medicinal; Protective Agents; Rats; Saponins; Viburnum | 2005 |
Preliminary studies on antihepatotoxic effect of Physalis peruviana Linn. (Solanaceae) against carbon tetrachloride induced acute liver injury in rats.
Topics: Animals; Antioxidants; Biomarkers; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Flavonoids; Glutathione; Hexanes; India; Lethal Dose 50; Liver; Liver Diseases; Male; Malondialdehyde; Phenols; Physalis; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Saponins; Solvents; Water | 2007 |
Inhibitory effects of saikosaponin-d on CCl4-induced hepatic fibrogenesis in rats.
Topics: Alanine Transaminase; Animals; Carbon Tetrachloride; Hyaluronic Acid; Laminin; Liver; Liver Cirrhosis, Experimental; Male; Oleanolic Acid; Rats; Rats, Sprague-Dawley; Saponins; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2007 |
Curcumin or saikosaponin a improves hepatic antioxidant capacity and protects against CCl4-induced liver injury in rats.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Curcumin; Glutathione; Lipids; Liver; Liver Diseases; Male; Oleanolic Acid; Rats; Rats, Sprague-Dawley; Saponins; Superoxide Dismutase | 2008 |
Effects of the extracts of Pycanthus angolensis against chemically induced acute hepatotoxicity.
Topics: Alkaloids; Animals; Antioxidants; Bile Acids and Salts; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cholesterol; Glutathione; Liver; Male; Plant Extracts; Plants; Rats; Rats, Wistar; Saponins | 2007 |
Relationship between anti-fibrotic effect of Panax notoginseng saponins and serum cytokines in rat hepatic fibrosis.
Topics: Animals; Carbon Tetrachloride; Cytokines; Disease Models, Animal; Liver Cirrhosis; Male; Panax notoginseng; Rats; Rats, Sprague-Dawley; Saponins | 2009 |
Asiatic acid derivatives protect primary cultures of rat hepatocytes against carbon tetrachloride-induced injury via the cellular antioxidant system.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Cells, Cultured; Hepatocytes; Male; Rats; Rats, Wistar; Saponins; Triterpenes | 2009 |
Curcumin and saikosaponin a inhibit chemical-induced liver inflammation and fibrosis in rats.
Topics: Animals; Anti-Inflammatory Agents; Bupleurum; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Collagen; Curcuma; Curcumin; Cytokines; Dietary Supplements; Drug Therapy, Combination; Fibrosis; Hydroxyproline; Inflammation; Liver; Male; NF-kappa B; Oleanolic Acid; Phytotherapy; Plant Extracts; Plant Roots; Random Allocation; Rats; Rats, Sprague-Dawley; Rhizome; Saponins; Transforming Growth Factor beta1 | 2010 |
Effect of purified saponin mixture from Astragalus corniculatus on enzyme- and non-enzyme-induced lipid peroxidation in liver microsomes from spontaneously hypertensive rats and normotensive rats.
Topics: Animals; Antioxidants; Ascorbic Acid; Astragalus Plant; Carbon Tetrachloride; Disease Models, Animal; Iron Compounds; Lipid Peroxidation; Malondialdehyde; Microsomes, Liver; NADP; Oxidative Stress; Plant Extracts; Rats; Rats, Inbred SHR; Rats, Wistar; Saponins; Spectrophotometry | 2010 |
A novel hepatoprotective saponin from Celosia cristata L.
Topics: Animals; Carbon Tetrachloride; Celosia; Chemical and Drug Induced Liver Injury; Dimethylformamide; Dose-Response Relationship, Drug; Liver; Mice; Mice, Inbred ICR; Molecular Structure; Random Allocation; Saponins | 2010 |
Hepatoprotective effects of total saponins isolated from Taraphochlamys affinis against carbon tetrachloride induced liver injury in rats.
Topics: Animals; Apocynaceae; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Liver; Liver Function Tests; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Sprague-Dawley; Saponins | 2012 |
Protective effects of a purified saponin mixture from Astragalus corniculatus Bieb., in vivo hepatotoxicity models.
Topics: Acetaminophen; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Astragalus Plant; Biotransformation; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Glutathione; L-Lactate Dehydrogenase; Liver; Liver Function Tests; Male; Malondialdehyde; Plant Extracts; Rats; Rats, Wistar; Saponins; Silymarin | 2013 |
Protective effects of the total saponins from Rosa laevigata Michx fruit against carbon tetrachloride-induced acute liver injury in mice.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chromatography, Liquid; Cytochrome P-450 CYP2E1; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Gene Expression Regulation; Liver; Male; Mice; Microscopy, Electron, Transmission; Protective Agents; Rosa; Saponins | 2013 |
[Effect of Panax notoginseng saponins on cytokines in liver fibrosis rats].
Topics: Animals; Carbon Tetrachloride; Colchicine; Cytokines; Disease Models, Animal; Gene Expression Regulation; Liver; Liver Cirrhosis, Experimental; Male; NF-kappa B; Panax notoginseng; Random Allocation; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Saponins; Tumor Necrosis Factor-alpha | 2013 |
Protective effects of the total saponins from Dioscorea nipponica Makino against carbon tetrachloride-induced liver injury in mice through suppression of apoptosis and inflammation.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Dioscorea; Male; Mice; Plant Extracts; Saponins | 2014 |
Antioxidant activities of saponins extracted from Radix Trichosanthis: an in vivo and in vitro evaluation.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Drugs, Chinese Herbal; L-Lactate Dehydrogenase; Male; Mice; Oxidative Stress; Plant Extracts; Saponins | 2014 |
The protective effect of Esculentoside A on experimental acute liver injury in mice.
Topics: Animals; Apoptosis; Carbon Tetrachloride; Cell Proliferation; Chemical and Drug Induced Liver Injury; Immunohistochemistry; In Situ Nick-End Labeling; Inflammation; Interleukin-1beta; Interleukin-6; Mice; Oleanolic Acid; Oxidative Stress; Reactive Oxygen Species; Saponins; Signal Transduction; Sincalide | 2014 |
Hepatoprotective and antiviral efficacy of Acacia mellifera leaves fractions against hepatitis B virus.
Topics: Acacia; Animals; Antioxidants; Antiviral Agents; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Hep G2 Cells; Hepatitis B virus; Humans; Plant Extracts; Plant Leaves; Rats; Saponins; Tannins | 2015 |
Protective Effect of the Total Saponins from Rosa laevigata Michx Fruit against Carbon Tetrachloride-Induced Liver Fibrosis in Rats.
Topics: Actins; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Collagen; Down-Regulation; Fibronectins; Fruit; Glutathione; Hydroxyproline; Liver; Liver Cirrhosis; Male; Malondialdehyde; Matrix Metalloproteinases; Oxidative Stress; Rats; Rats, Sprague-Dawley; Rosa; Saponins; Signal Transduction; Superoxide Dismutase | 2015 |
Trillin Reduces Liver Chronic Inflammation and Fibrosis in Carbon Tetrachloride (CCl4) Induced Liver Injury in Mice.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; Carbon Tetrachloride; Dioscorea; Enzyme-Linked Immunosorbent Assay; Hepatitis; Humans; Injections, Intraperitoneal; Interleukin-1beta; Interleukin-6; Liver Cirrhosis; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; NF-kappa B; Saponins; Superoxide Dismutase; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2016 |
Astragaloside Alleviates Hepatic Fibrosis Function via PAR2 Signaling Pathway in Diabetic Rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus, Experimental; Gene Expression Regulation; Interleukin-1beta; Interleukin-6; Liver Cirrhosis; Male; Protein Kinase C-epsilon; Rats; Rats, Sprague-Dawley; Receptor, PAR-2; Saponins; Signal Transduction; Streptozocin; Transforming Growth Factor beta1; Triterpenes; Tumor Necrosis Factor-alpha | 2017 |
Magnesium isoglycyrrhizinate promotes the activated hepatic stellate cells apoptosis via endoplasmic reticulum stress and ameliorates fibrogenesis in vitro and in vivo.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Carbon Tetrachloride; Cell Line; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Cyclin-Dependent Kinase Inhibitor p27; eIF-2 Kinase; Endoplasmic Reticulum Stress; Gene Expression Regulation; Hepatic Stellate Cells; Liver; Liver Cirrhosis; Male; Mice; Mice, Inbred ICR; Oncogene Proteins; Saponins; Signal Transduction; Triterpenes; Unfolded Protein Response | 2017 |
Saikosaponin‑d alleviates carbon‑tetrachloride induced acute hepatocellular injury by inhibiting oxidative stress and NLRP3 inflammasome activation in the HL‑7702 cell line.
Topics: Apoptosis; Carbon Tetrachloride; Cell Line; Cell Survival; Chemical and Drug Induced Liver Injury; Cytokines; Inflammasomes; Inflammation Mediators; Liver; Malondialdehyde; NLR Family, Pyrin Domain-Containing 3 Protein; Oleanolic Acid; Oxidative Stress; Saponins | 2018 |
Magnesium isoglycyrrhizinate ameliorates liver fibrosis and hepatic stellate cell activation by regulating ferroptosis signaling pathway.
Topics: Animals; Carbon Tetrachloride; Cell Death; Cell Line; Chemical and Drug Induced Liver Injury; Cytoprotection; Dose-Response Relationship, Drug; Heme Oxygenase (Decyclizing); Hepatic Stellate Cells; Iron; Iron Overload; Lipid Peroxidation; Liver; Liver Cirrhosis, Experimental; Male; Oxidation-Reduction; Rats, Sprague-Dawley; Saponins; Signal Transduction; Time Factors; Triterpenes | 2018 |
The inhibition of Hippo/Yap signaling pathway is required for magnesium isoglycyrrhizinate to ameliorate hepatic stellate cell inflammation and activation.
Topics: Adaptor Proteins, Signal Transducing; Animals; Anti-Inflammatory Agents; Becaplermin; Carbon Tetrachloride; Cell Cycle Proteins; Chemical and Drug Induced Liver Injury; Cytokines; Hepatic Stellate Cells; Hippo Signaling Pathway; Inflammation Mediators; Liver; Liver Cirrhosis, Experimental; Male; Mice, Inbred C57BL; NF-kappa B; Phosphoproteins; Protein Serine-Threonine Kinases; Saponins; Signal Transduction; Triterpenes; YAP-Signaling Proteins | 2018 |
Saikosaponin-d protects against liver fibrosis by regulating the estrogen receptor-β/NLRP3 inflammasome pathway.
Topics: Animals; Carbon Tetrachloride; Cells, Cultured; Estrogen Receptor beta; Inflammasomes; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Oleanolic Acid; Protective Agents; Saponins | 2021 |
Saikosaponin-d alleviates hepatic fibrosis through regulating GPER1/autophagy signaling.
Topics: Animals; Autophagy; Carbon Tetrachloride; Cells, Cultured; China; Fibrosis; Hepatic Stellate Cells; Humans; Liver; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Oleanolic Acid; Receptors, Estrogen; Receptors, G-Protein-Coupled; Saponins; Signal Transduction; Transforming Growth Factor beta | 2021 |